LRR8_g-1

Species: S.moellendorffii
Alias: LRR8_g-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_g-1.AA Protein None 729 None Fasta, JSON
LRR8_g-1.NA RNA None 2190 None Fasta, JSON
LRR8_g-1.kin_dom Protein Kinase Domain None 102 None Fasta, JSON

Protein domain

Protein domains of LRR8_g-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_g-1.AA LRRNT_2 29-73 41 2.9e-15 52.5 Pfam 1-46 (46) Show / Hide
Range on Protein: 29-73
Range on HMM: 1-46/46
Sequence Identity: 41% (20 aa)

ANPDVDTLLRIKSYIL--DP-LNKLESWKIESSQASAAPCSWLGITCD
.| |...||..|| .   || ...|.||.  ||  .. .||| |.|||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSS--DSDCCSWTGVTCD

LRR_1 LRR8_g-1.AA LRR_1 93-115 33 0.881582 6.94 Pfam 1-26 (26) Show / Hide
Range on Protein: 93-115
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

VIIAIDLSS-S--NLSGTISPE-IGSL
 .  .|||.    ||.|.|.|. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 117-139 44 0.000186 19.97 Pfam 1-26 (26) Show / Hide
Range on Protein: 117-139
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ALQSLNLAH-N--NFTGPIPPS-LAQC
 ||.|.| . |  |.|| |||| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 141-164 39 0.002586 15.92 Pfam 1-26 (26) Show / Hide
Range on Protein: 141-164
Range on HMM: 1-26/26
Sequence Identity: 39% (11 aa)

SLKHLNLSD-N--ALS-EKIPAVLFTGL
.|.||.||. |   |. . ||   | .|
NLQHLDLSGCNCCNLTGH-IPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 166-188 29 7.513271 3.64 Pfam 1-26 (26) Show / Hide
Range on Protein: 166-188
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLETVDFWI-N--SLTGTIPRE-VGYS
.|.. |.   |  .|||.|| .     
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 190-212 48 2.5e-05 23.06 Pfam 1-26 (26) Show / Hide
Range on Protein: 190-212
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

RLEHLDLGG-N--YLEGSIPAE-LFNL
.|.||||.| |   |.|.|| . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 214-236 37 0.000324 19.12 Pfam 1-26 (26) Show / Hide
Range on Protein: 214-236
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLRYLTLAG-N--SLVGSIPEE-ISKL
.|..| | | |  .|.|.||.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 238-260 29 0.003397 15.5 Pfam 1-26 (26) Show / Hide
Range on Protein: 238-260
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RLEWIYLGY-N--QLNGSIPRG-IGSL
.|. ..|.. |  .| |.|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 263-286 44 0.003062 15.66 Pfam 1-26 (26) Show / Hide
Range on Protein: 263-286
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

SLLHLDLVF-N--DLSGPIPGDSIANL
.| ||||   |   |.| || ... ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 288-310 37 0.002471 15.99 Pfam 1-26 (26) Show / Hide
Range on Protein: 288-310
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLEYLFLYT-N--RLSGEIPAS-LGRL
.|..| |   |  .|.|.|| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 312-334 40 0.006589 14.48 Pfam 1-26 (26) Show / Hide
Range on Protein: 312-334
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLISLDLSN-N--TLSGAIPGS-LADI
.| .||||. |   |.| || | .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 336-358 33 0.033846 11.96 Pfam 1-26 (26) Show / Hide
Range on Protein: 336-358
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

TLEIVNLFQ-N--NLSGPVPVS-FSAM
.|.. .|   |  ||.| .| | | ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 369-391 37 0.002439 16.01 Pfam 1-26 (26) Show / Hide
Range on Protein: 369-391
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLQILSLQQ-N--SIEGEIPAS-IFQL
.||.|.|.  |  ...|.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 393-415 25 65.574709 0.3 Pfam 1-26 (26) Show / Hide
Range on Protein: 393-415
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ALVELQLGA-N--EFRGEIPAT-IGEA
 | .| |.  |   . |.||   .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 417-439 40 0.000417 18.73 Pfam 1-26 (26) Show / Hide
Range on Protein: 417-439
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

LLTELDLSG-N--HLSGGIPSQ-IGHC
 |..||||| |  .|.| ||.  . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 441-463 37 0.021344 12.67 Pfam 1-26 (26) Show / Hide
Range on Protein: 441-463
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLVSIDLSE-N--MFTGFIPAS-LGHI
.| ..|||  |   .|| || | . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 465-487 37 0.028961 12.2 Pfam 1-26 (26) Show / Hide
Range on Protein: 465-487
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

TLSTLDLSR-N--LLEGGIPAT-LASM
.| .||||. |   |.| ||   . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR8_g-1.AA LRR_1 489-513 28 0.011005 13.69 Pfam 1-26 (26) Show / Hide
Range on Protein: 489-513
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

SLEFLNISE-N--RLSGAFPSSGALSAI
.|. |..|  |  .|.| .|.| .. . 
NLQHLDLSGCNCCNLTGHIPPS-CF-NL

Kinase LRR8_g-1.AA TKL 607-693 25 3.6e-13 43.77 In-house 80-174 (364) Show / Hide
Range on Protein: 607-693
Range on HMM: 80-174/364
Sequence Identity: 25% (27 aa)

SRLRHENVAKVLGICTGKES-------------AMVLFQHLPQGSLASVLFPGEKPDAGALGWNERYDICLGTARGLAFLHS-RP-----ERILHGSLSP
|||||.|. . .|.|.  ..              .   .  | ||| ..|            |. | ...|..|||...||| .|       |.|  | .
SRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKS

HSVFLD
. ...|
KNILVD

Kinase LRR8_g-1.AA TK 598-693 11 1.9e-09 27.03 In-house 87-274 (486) Show / Hide
Range on Protein: 598-693
Range on HMM: 87-274/486
Sequence Identity: 11% (22 aa)

ELMRRMEAVS--RLRHENVAKVLGICTGK------------ESAMVLFQHLPQGS----LASVLF--PGEKPD---------------------------
|... |.  .   ..|.|. . .|.|| .            |  |..  . | |.    | . |   .... .                           
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

------------------------------------------AGALGWNERYDICLGTARGLAFLHSRPE----RILHGSLSPHSVFLD
                                           . |   ..  .|.  |.|...|||..     .. |. |  . . ..
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVG

Kinase LRR8_g-1.AA IRAK 603-675 32 2.6e-09 29.34 In-house 54-127 (317) Show / Hide
Range on Protein: 603-675
Range on HMM: 54-127/317
Sequence Identity: 32% (24 aa)

MEAVSRLRHENVAKVLGICTGKESAMVLFQHLPQGSLASVLFPGEKPDA-GALGWNERYDICLGTARGLAFLHS
... .|.||.|.  ..| ||. .     .. .| |||   |      ..  .| |  | .||.|||.|. |||.
LKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQ

Kinase LRR8_g-1.AA TKL-ciliate2 598-682 31 1.1e-07 21.13 In-house 42-122 (273) Show / Hide
Range on Protein: 598-682
Range on HMM: 42-122/273
Sequence Identity: 31% (27 aa)

ELMRRMEAVSRLRHENVAKVLGICTGKESAMVLFQHLPQGSLASVLFPGEKPDAGALGWNERYDICLGTARGLAFLHSRPERILH
. .   .|.  ||| |.   || ||      ...    .||| |.|   . .    | | .|  | |  |||  .|||    |.|
DFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVR----LTWEDRRRIALDIARGVHYLHSSNPPIIH

Kinase LRR8_g-1.AA EGFR 584-639 19 2e-07 20.49 In-house 33-87 (258) Show / Hide
Range on Protein: 584-639
Range on HMM: 33-87/258
Sequence Identity: 19% (11 aa)

VKRFLRSSGLGSDSELMRRMEAVSRLRHENVAKVLGICTGKESAMVLFQHLPQGSL
.| .  ..|  .  |... . .. ...|... ..||.| ...  ..  | .| |.|
IKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQ-MQLVTQYMPYGCL

Kinase LRR8_g-1.AA TK-Unique 584-700 20 5e-07 20.42 In-house 35-174 (294) Show / Hide
Range on Protein: 584-700
Range on HMM: 35-174/294
Sequence Identity: 20% (28 aa)

VKRFLRSSGLGSDSELMRRMEAVSRLR-HENVAKVLGICTGK-ESAMVLFQHLPQGSLASVLF---------------------PGEKPDAGALGWNERY
||   ... . ........ .  . |  |.|. . ||.|| . |. | .. ..|.|.| . |                      . .||   ..     |
VKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLY

DICLGTARGLAFLHSRPERILHGSLSPHSVFLDVSSRPKL
 .. . |.|...|.| ...| |. |. . |.|    . |.
HFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKI

Kinase LRR8_g-1.AA UTK 602-676 26 7.3e-07 19.51 In-house 54-137 (296) Show / Hide
Range on Protein: 602-676
Range on HMM: 54-137/296
Sequence Identity: 26% (22 aa)

RMEAV-----SRLR-HENVAKVLGICTGKESAMVLFQHLPQGSLASVLF-PGEKPD-AGALGWNE-RYDICLGTARGLAFLHSR
..||      .... |.||....|.||  |  |..  . ..|.|.|.|   ...|. ....  .. | . ..  |||...|||.
MEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSC

Kinase LRR8_g-1.AA Pkinase_Tyr 607-677 24 2e-06 22.34 Pfam 58-131 (270) Show / Hide
Range on Protein: 607-677
Range on HMM: 58-131/270
Sequence Identity: 24% (19 aa)

SRL-RHENVAKVLGICT-GKES--AMVLFQHLPQGSLASVLFPGEKP--DAGALGWNERYDICLGTARGLAFLHSRP
. | .|.|. . .|.||  .|.   .. . . | |.| . |    |.  | ..|   .  ..|.  |.|...|.|..
KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL---RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN

Kinase LRR8_g-1.AA MLK 604-693 22 3e-06 17.77 In-house 57-161 (291) Show / Hide
Range on Protein: 604-693
Range on HMM: 57-161/291
Sequence Identity: 22% (24 aa)

EAVSRLRHEN----VAKVLGICTGKES-AMVLFQHLPQGSLASVL---FP-------GEKPDAGALGWNERYDICLGTARGLAFLHS-RPERILHGSLSP
. ...|.|.|    . ...|.|.  ..   .. . .. |||..||    .       ..|  ..        ...|  |||...|||  |  | |  | .
RHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKS

HSVFLD
| . .|
HNILID

Kinase LRR8_g-1.AA DRK 597-682 23 7e-06 16.0 In-house 42-123 (258) Show / Hide
Range on Protein: 597-682
Range on HMM: 42-123/258
Sequence Identity: 23% (20 aa)

SELMRRMEAVSRLRHENVAKVLGICTGKESAMVLFQHLPQGSLASVLFPGEKPDAGALGWNERYDICLGTARGLAFLHSRPERILH
.|. |  .  ..||| |.   .| |.   .  .    .| |||...|      ..  . |  .  . .  |.|. .||..   |.|
NEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH----DESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIH

Kinase LRR8_g-1.AA Ror 604-639 30 4.2e-05 16.69 In-house 54-89 (308) Show / Hide
Range on Protein: 604-639
Range on HMM: 54-89/308
Sequence Identity: 30% (11 aa)

EAVSRLRHENVAKVLGICTGKESAMVLFQHLPQGSL
.....| | |. . ||.|| ...   ||  ...| |
MLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDL

TyrKc LRR8_g-1.AA TyrKc 579-725 13 0.000494 -157.42 SMART 13-280 (280) Show / Hide
Range on Protein: 579-725
Range on HMM: 13-280/280
Sequence Identity: 13% (38 aa)

GNVFS--------VKRFLRSSGLGSDSELMRRMEAVSRL--RHENVAKVLGICTGK-------ESAMVLFQHLPQGSLASVL-FPGEKPDAGALGWNERY
| |.         ||    ..      ..|| ..  ..|  .|.|. . .|.|| .       |  |... . | |.| . |  ...|     | . .  
GEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-----LCMKDLL

DICLGTARGLAFLHSRP--------------------------------------------------ER------------ILHG---------------
..|.  |.| ..|||..                                                  ..            | .|               
SFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCM

------------S-----LSPHSVFLDVSSR-----PKL---------LVEFATLEGHCCYLAPGN----KELPEFF
                  .|.  |. .| ..     |.            |  ..   |.   | .    .|. |.|
WEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF