Gene LRR8_t (S.moellendorffii)
LRR8_t
Species: S.moellendorffii
Alias: LRR8_t
External Links:
Annotation:
Sequence
Protein domains of LRR8_t.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRRNT_2 | LRR8_t.AA | LRRNT_2 | 47-87 | 43 | 6.1e-16 | 54.69 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 47-87 Range on HMM: 1-46/46 Sequence Identity: 43% (20 aa) ASQDAVNLLALKLDIV--DG-LGYLSDWKGST--TTPCSWTGVTCD ...|. |||.| .. |. .|.||.|. |. ...||||||||| HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD |
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| LRR_1 | LRR8_t.AA | LRR_1 | 91-113 | 25 | 18.520172 | 2.25 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 91-113 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) QISSLNLAS-M--NLTGRVNEN-IGLL .. .|.| . |||| . .. . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 115-137 | 33 | 0.002128 | 16.22 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 115-137 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) SLSVLNLSD-N--SLSGDLPLA-MTSL .| .|.||. | .|.|..| .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 139-161 | 37 | 0.007551 | 14.27 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 139-161 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) NLDTLDISE-N--QFTGRLTNA-IANL || .||.| | ..|| . . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 163-185 | 25 | 13.3883 | 2.75 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 163-185 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) LLTFFSAHD-N--NFTGPLPSQ-MARL |. . . | |.|| .|. | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 187-209 | 40 | 0.05162 | 11.31 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 187-209 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) DLELLDLAG-S--YFSGSIPPE-YGNL |. ||| | ..|.|||. || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 211-233 | 48 | 0.000115 | 20.71 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 211-233 Range on HMM: 1-26/26 Sequence Identity: 48% (13 aa) KLKTLKLSG-N--LLTGEIPAE-LGNL .|..| ||| | |||.|| . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 235-257 | 40 | 0.126479 | 9.93 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 235-257 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) ELNHLELGY-N--NYSGGIPRE-FGKL | || |.. | | .| || . | .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 259-281 | 37 | 0.011149 | 13.67 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 259-281 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) QLEYLDMSL-T--GLSGSIPAE-MGNL .|..||.| . |.|.|| . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 283-305 | 25 | 4.498659 | 4.43 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 283-305 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) QCHTVFLYK-N--RLSGILPPE-IGNM . . | | .|.| .||. . |. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 307-329 | 44 | 0.000596 | 18.18 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 307-329 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) GLMSLDISD-N--QLSGPIPES-FSRL | .||.|. | .|.| ||.| | | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 331-353 | 37 | 0.231366 | 9.0 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 331-353 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RLTLLHLMM-N--NLNGSIPEQ-LGEL .|. |.| | || |.||. . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 355-377 | 33 | 0.013114 | 13.42 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 355-377 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) NLETLSVWN-N--LITGTIPPR-LGHT ||..|.. . | .||.|||. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 403-424 | 37 | 0.025934 | 12.37 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 403-424 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLIKLELFS-N--SLTGTIPD--MTNC .| .| | . | .|||.||. |. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 379-402 | 25 | 0.794584 | 7.1 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 379-402 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) SLSWIDVSS-N--LISGEIPRGICKGG .| .|.|. | ..|.|| ... . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 434-448 | 31 | 72.263305 | 0.15 | Pfam | 9-26 (26) | Show / Hide |
Range on Protein: 434-448 Range on HMM: 9-26/26 Sequence Identity: 31% (6 aa) D-N--HLSGPIPAA-FGAM . | .|.| || | .. GCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 450-472 | 37 | 0.020395 | 12.74 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 450-472 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) NLTRLELSK-N--WLNGSIPED-ISAA ||..| || | | |.||.. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 474-496 | 33 | 0.057646 | 11.14 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 474-496 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) RLAFIDISS-N--RLEGSIPPR-VWSI .| .|.|. | .|.|.|||. . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 498-520 | 37 | 0.75436 | 7.18 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 498-520 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) QLQELHAAG-N--ALSGELTPS-VANA .||.|. | | |.|.. || | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 522-544 | 37 | 0.054373 | 11.23 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 522-544 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RMLVLDLSE-N--KLQGPIPPE-IVYC . .|||| | .|.| |||. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 546-568 | 33 | 0.018382 | 12.9 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 546-568 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) KLVTLNLRK-N--TLSGQIPVA-LALL .| .|.|. | |.|.|| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 570-592 | 40 | 0.039044 | 11.74 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 570-592 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) VLSVLDLSW-N--SLQGRIPAQ-FSQS | .|||| | .|.| || | . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_t.AA | LRR_1 | 594-614 | 30 | 0.166137 | 9.51 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 594-614 Range on HMM: 1-26/26 Sequence Identity: 30% (8 aa) SLEDFNVSY-N--SLSGQLPTS--GL .|. ..|. | .|.|..| | .| NLQHLDLSGCNCCNLTGHIPPSCFNL |
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| Kinase | LRR8_t.AA | TKL | 731-998 | 21 | 4.6e-63 | 215.83 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 731-998
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)
IGKGGMGVVYKAEMAS---------GEVVALKQLCNNKESYYTD-------------------------QGFLSEVKVLGGIRHRNIVRLLGYCSNHHT-
||.|| |.|||.. |..|| |.. . .. |. . . |.... .|| |||...||| .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------DMLLYEYMPNGSLSDLLHGQKNSSSLLADWVARYNIAMGVAQGLAYLHHDCF----PHVIIHRDVKSSNILLDHNMD-----------
.. .||.|.||| ..|| | | ..|...|.|..||| . . . ||||| ||.|||.| |.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA
---ARVADFGLAKLIEARES--------------------MSVVAGSYGYIAPEYAYTM----------------KVREKGDIYSYGVVLLELLTGKRPI
. ..||||.. .. ... . . |.... ||| . . || |.||.|.|| |.||..||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY
EPEFGEGSNIVDWVHSK-LRKGRLVEVLDWSIG----------CCESVREEMLLVLRVAMLCTSRAPRDRPTMRDVVSML
. . . . | . .. ... .. | | .|... ..| . .. | . |..||.. .... |
YDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSM---KKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | LRR8_t.AA | IRAK | 726-928 | 35 | 3.3e-55 | 189.75 | In-house | 2-223 (317) | Show / Hide |
Range on Protein: 726-928 Range on HMM: 2-223/317 Sequence Identity: 35% (80 aa) RDKNIIGKGGMGVVYKAEMASGE-VVALKQLCNNKESYYT--DQGFLS---EVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPNGSLSDLLHGQKNSS | ||.|| |.||.... . ..| | | ..... . .| |.. |.||. .|| ||| |.|||. | |.||||||| | |..|... HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC SL--LADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLI---EARESMSV-------VAGSYGYIAPEYAY--TMK .. | | | |. | | |. .|| . |||.|.||.||||| .. . .||||. ...|. .. | |. | .||. . . . PPKPLS-WHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ VREKGDIYSYGVVLLELLTGKRP | |.|| |.||||.||| |. LTKKTDVYSFGIVLLEVLTGCRA |
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| Kinase | LRR8_t.AA | MLK | 725-928 | 29 | 2.2e-49 | 169.45 | In-house | 1-235 (291) | Show / Hide |
Range on Protein: 725-928 Range on HMM: 1-235/291 Sequence Identity: 29% (70 aa) IRDKNIIGKGGMGVVYKAEMASGE----VVALKQLCNNK----ESYYTDQGFLSEVKVLGGIRHRN----IVRLLGYCSNH-HTDMLLYEYMPNGSLSDL |. . .||.|..|.|.|... . .||.|. .. ..| .. | |.. | ..|.| |....| |... . .. ||...|||... IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHGQK----------NSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDH------NMDARVADFGLAKLIEARES-MSVVAGSYG |||.. . .. | |.|. .|.|..||| . |. ||||| ||.|||.|. .......|||... . ... | ||.| LHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYLHSMA-PKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA YIAPEY---AYTMKVREKGDIYSYGVVLLELLTGKRP . ||| . |. || |..|.|||| |.||.. | WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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| Kinase | LRR8_t.AA | TKL-Unique | 727-928 | 34 | 5e-42 | 145.93 | In-house | 1-233 (290) | Show / Hide |
Range on Protein: 727-928
Range on HMM: 1-233/290
Sequence Identity: 34% (81 aa)
DKNIIGKGGMGVVYKAEMASGEVVALKQLC-NNKESYYTDQGFLSEVKVLGGIR-HRNIVRLLGYCS----NHHTDMLLYEYMPNGSLSDLLH-----GQ
. | || ||.|.|||.. . |. ||.||. |.. | | | .||... .. | |||.. ||| . ||.| ||| |.||
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN
KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHN-----MDARVADFGLAKLIE--ARESMS--------VVAGSYGYIAPEY
|.... .. |...| .|||. |||| | ||||| ||||.|.| | . ....||||.|. ... . .. ||. ..|||
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV
AYT--MKVREKGDIYSYGVVLLELLTGKR------P
. || |.||.|.|| |..|.|. |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
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| Kinase | LRR8_t.AA | Dicty4-Unclassified | 725-928 | 33 | 4.3e-41 | 138.46 | In-house | 1-207 (263) | Show / Hide |
Range on Protein: 725-928 Range on HMM: 1-207/263 Sequence Identity: 33% (73 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKESYY--TDQGFLSEVKVLGGIRHRNIVRLLGYCSNH----HTDMLLYEYMPNGSLSDLLH---GQ |. |||| . |.| | || | . || . | |. || .|| | | | |.. ||| | | . | |. | | . | IQIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE KNSSSLLAD--WVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGSYGYIAPEYAYTMKVREKGDIY .. . | | .. .|. .|||...|| .||||.||||||.| . ...||||.. |. | .|| .|| | |.| QQQPIKLDDTLIIK---YAFDIAQGMQHLHT----RNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVY SYGVVLLELLTGKRP ||...| ||.|| | SYAMMLYELATGDEP |
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| Kinase | LRR8_t.AA | Pkinase | 725-926 | 27 | 8.7e-41 | 145.3 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 725-926 Range on HMM: 1-209/293 Sequence Identity: 27% (61 aa) IRDKNIIGKGGMGVVYKAEMASGEV-VALKQLCNNKESYYTDQGFLS--EVKVLGGIRHRNIVRLLGYCSNHHTDML-LYEYMPNG----SLSDLLH-GQ .. . .||.|..|.|||. . . ||.|... .|. || . |.... ..| |||||.... . .... ||...| .|.|... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDA----RVADFGLAKL--IEARESMSVVAGSYGYIAPEYAY-TMKVRE ... . . .|... ... ...||.|.| |||||.|..|||.|.|.. ...||||||. . . |....|...|.||| . HGCFY-FSEWECK-FYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP KGDIYSYGVVLLELLTGK | |..|.|..| |.|.|. KVDMWSCGCILYEMLCGR |
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| Kinase | LRR8_t.AA | Dicty4 | 725-928 | 34 | 4e-38 | 124.86 | In-house | 1-216 (277) | Show / Hide |
Range on Protein: 725-928 Range on HMM: 1-216/277 Sequence Identity: 34% (75 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKES--YYTDQGFLSEVKVLGGIRHRNIVRLLGYCS----NHHTDMLLYEYMPNGSLSDLLHG--QK | ..||||. | |||. | || | | |... .. . |. ||. .. ||| ||. ..|.| . . . |||| |.| ||| INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE NSSSLLADWVARYN---IAMGVAQGLAYLHH-DCFPHVIIHRDVKSSNILLDHNMDARVADFGLAK----LIEARESMSVVAGSYGYIAPEYAYTMKVRE .| || . .| .|.|...|| .. |||||| ||.|.| | |. . |.||||.. .. .. ..|. .. ||| | QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP---VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE KGDIYSYGVVLLELLTGKRP | | ||.| || |.||.. | KADVYSFGIVLWEILTRQEP |
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| Kinase | LRR8_t.AA | LISK | 730-928 | 27 | 8.5e-38 | 120.25 | In-house | 1-238 (296) | Show / Hide |
Range on Protein: 730-928 Range on HMM: 1-238/296 Sequence Identity: 27% (67 aa) IIGKGGMGVVYKAEMA-SGEVVALKQLCN-----NKESYYTDQGFLSEVKVLGGIRHRNIVRLLGYCSN-HHTDMLLYEYMPNGSLSDLLHGQKNSSSLL .||||. | ||| . .|.|.|.|.. . |...| .| ||... .||.|||. | | . ... ||. | | ..|. . .. | EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKF--MLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL ADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHN----MDARVADFGLAKLIEARE---------------------------------- | | .|| ..|.|..||| . ||||| || |.|.. | ..|.|||.|.... .. P-WPQRVKIALDIACGMSYLHSMN----IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQR --SMSVVAGSYGYIAPEYAYTMKVREKGDIYSYGVVLLELLTGKRP .|... |. ||| .. |. |..|.|.||.|. |.... KRRMTIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA |
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| Kinase | LRR8_t.AA | TK | 725-998 | 15 | 5.8e-37 | 120.91 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 725-998
Range on HMM: 1-486/486
Sequence Identity: 15% (77 aa)
IRDKNIIGKGGMG---VVYKAEMASG--------------------------EVVALKQLCNNKESYYT-DQG--------------FLSEVKVLGG--I
|. . .|.| | .|||.|. .. . || |.| .. . . ...| |..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
RHRNIVRLLGYCSNHHTD------------MLLYEYMPNGS----LSDLLHGQKN---------------------------------------------
.| |||||.|.|. . . |.. ||||.|. | | |. ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
---------SSSLLADWVARYN----------------IAMGVAQGLAYLHHDCFPHV---IIHRDVKSSNILLDHNMD-----------ARVADFG---
.. ..| . . . ... .|.|..||| . ..|||. |.|...|. ...||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----LAKLIEARESMSVVAGSYG---------------------------YIAPEYAY---------TMKVREKGDIYSYGVVLLELLT-GKRPIEPEF
||. |. .. .. . .. . ||| . | .| |..|.||.. |..| |. | ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
GEGSNIV----DWVHSKLRKG-RL--------VEVLDWS--IGCCE----SVREEM-----LLVLRVAMLCTSRAPRDRPTMRDVVSML
.. . | .||.| || . . .|.. .. .. . | .. |.||||.......|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | LRR8_t.AA | STE | 725-928 | 23 | 2.6e-33 | 114.99 | In-house | 1-267 (359) | Show / Hide |
Range on Protein: 725-928 Range on HMM: 1-267/359 Sequence Identity: 23% (65 aa) IRDKNIIGKGGMGVVYKAEMA----------------SGEVVALKQLCNNKES---------------YYTDQGFLSEVKVLGGIR--HRNIVRLLGYCS .. .||||. |.|||| .||..| ||. .... | .| |.|.. . | |||. .|.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF NH-------HTDMLLYEYMPNGSLSDLLH---GQKNSSSLL--------ADWVARYNIAMGVAQG-LAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVA . .. . |||..|||.|... | ... .. ...|. |. . .| |.||| |||||.|..|||| . . KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY--ICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLC DFGLAKLIEA-----------------RESMSVVAGSYGYIAPEYAYTMKVR------EKGDIYSYGVVLLELLTGKRP |||... .. . ..|. . ||| .. .| ||.| | ...|..||| | DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP |
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| Kinase | LRR8_t.AA | S_TKc | 725-1005 | 22 | 1.3e-32 | 115.57 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 725-1005 Range on HMM: 1-231/231 Sequence Identity: 22% (66 aa) IRDKNIIGKGGMGVVYKAEMAS-GEVVALKQLCNNKESYYTDQGFLSEVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPN--GSLSDLLHGQKN--SS . ..||||..|.|||. . |..||.|.. . ...|...| .| |||.|.... . . . ||... |.| |... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR SLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGSYGYIAPEYAYTMKVRE-KGDIYSYGVV . . .||. .. ....|.|.| |||||.| .|||||. ..|||||... . . |. |.||| . | |..| |.. FPFPE-HARFYMYQ-ICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI LLELLTGKRPIEPEFGEGSNIVDWVHSKLRKGRLVEVLDWSIGCCESVREEMLLVLRVAMLCTSRAPRDRPTMRDVVS--MLIEAQPRR | |.|.|. | . . . . . .. . | . |..||| .. ..| . | LYEMLCGYPPFP----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | LRR8_t.AA | Pkinase_Tyr | 725-928 | 26 | 4.5e-27 | 92.33 | Pfam | 1-214 (270) | Show / Hide |
Range on Protein: 725-928 Range on HMM: 1-214/270 Sequence Identity: 26% (60 aa) IRDKNIIGKGGMGVVYKAEMA-----SGEVVALKQLCNNKESYYTDQG-----FLSEVKVLGGI-RHRNIVRLLGYCS-NHHT--DMLLYEYMPNGSLSD |. .|.| |.|||... . || | | .. ..... |..|.|.. . .| |||||.| |. .. ||||.|.| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD LLHGQKNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEARESMSVVAGS-----YGYIAPEYAYTMK |. .. .. . .... .|.|..||. .||||. |.|...|. ....|||||..|. . ..... ||| ..| YLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK VREKGDIYSYGVVLLELLT-GKRP .| |..|.||.. |..| |. | FTTKSDVWSFGVLMWEIFTYGEQP |
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| Kinase | LRR8_t.AA | LRRK | 771-928 | 32 | 1.6e-25 | 87.21 | In-house | 107-282 (351) | Show / Hide |
Range on Protein: 771-928 Range on HMM: 107-282/351 Sequence Identity: 32% (59 aa) EVKVLGGIRHRNIVRLLGYCSNHHTDMLLYEYMPNGSLSDLLHGQKNSS-SLLA-D--WVARYNIAMGVAQGLAYLHHDCFPHV--IIHRDVKSSNILL- || .. . .| ||| |.|.| .. .. ||.|.|.|...|| |... . . . | .. ||. .| |..||| | ||||| || |||| EVWIMSHLNHPNIVSLKGFCIHPL--CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS----HNPPIIHRDLKSPNILLW --D---------HNMDARVADFGLAKLIEARES--MSVVAGSYGYIAPEYAYTM---KVREKGDIYSYGVVLLELLTGK-RP . .. | .||||. . . . . . | |. ||| . || |.||.|..| ||||.. .| SSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP |
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| Kinase | LRR8_t.AA | TyrKc | 725-998 | 22 | 7.1e-23 | 83.24 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 725-998 Range on HMM: 1-280/280 Sequence Identity: 22% (69 aa) IRDKNIIGKGGMGVVYKAEMASGEVVALKQLCNNKESYYTDQGFLSEVKVLGGI--RHRNIVRLLGYCSNH-------HTDMLLYEYMPNGSLSDLLHGQ |. . ..| | |.|||... . || | | ... . |..| ... . .| |||||.|.|. . . |.. ||||.|.| | |. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH KNSSSLLADWVARYNIAMGVAQGLAYLHHDCFPHVIIHRDVKSSNILLDHNMDARVADFGLAKLIEAR-------ESMSV----VA---GSYGYIAPEYA .. . ... .|.| .|||. .|||| |.|...| ....||||.. |. . .. . . ||| RPK----LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI YTMKVREKGDIYSYGVVLLELLTGKRPIEPEFG------EGSNIVDWVHSKLRKGRLVEVLDWSIGCCESVREEM------LLVLRVAMLCTSRAPRDRP . | .| |..|.||.. |..| . .| | . . .. .| . | . ... . | . .. | . | ||| NYGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----------P-MSFVCCPDEMYQIMKQCWHEDPEDRP TMRDVVSML |...... . TFSEIHECF |
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| Kinase | LRR8_t.AA | LRRK | 725-755 | 18 | 1.5e-05 | 15.55 | In-house | 1-59 (351) | Show / Hide |
Range on Protein: 725-755 Range on HMM: 1-59/351 Sequence Identity: 18% (11 aa) IRDKNIIGKGGMG-VVYKAEMAS---------------------------GEVVALKQL .. . ||.|| | .||.|.. . .. || |.. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW |
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| Kinase | LRR8_t.AA | LRRK | 978-1000 | 26 | 0.001176 | 8.79 | In-house | 329-351 (351) | Show / Hide |
Range on Protein: 978-1000 Range on HMM: 329-351/351 Sequence Identity: 26% (6 aa) MLCTSRAPRDRPTMRDVVSMLIE ..| . |..||.. ..|. | . QHCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | LRR8_t.AA | MLK | 985-998 | 42 | 0.016349 | 4.69 | In-house | 278-291 (291) | Show / Hide |
Range on Protein: 985-998 Range on HMM: 278-291/291 Sequence Identity: 42% (6 aa) PRDRPTMRDVVSML |..||..| .|. | PHKRPSFRQIVQHL |
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| Kinase | LRR8_t.AA | LISK | 974-998 | 28 | 0.018168 | 3.6 | In-house | 272-296 (296) | Show / Hide |
Range on Protein: 974-998 Range on HMM: 272-296/296 Sequence Identity: 28% (7 aa) LRVAMLCTSRAPRDRPTMRDVVSML |.... |.. |..||. ..|. | LDLCFDCCKYDPKNRPSFKEIVQWL |
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| Kinase | LRR8_t.AA | Dicty4-Unclassified | 980-998 | 36 | 0.024983 | 3.74 | In-house | 245-263 (263) | Show / Hide |
Range on Protein: 980-998 Range on HMM: 245-263/263 Sequence Identity: 36% (7 aa) CTSRAPRDRPTMRDVVSML | . |. |||| ... | CWHNDPNKRPTMNQIIQYL |
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| Kinase | LRR8_t.AA | Pkinase_Tyr | 985-998 | 42 | 0.054624 | 7.36 | Pfam | 257-270 (270) | Show / Hide |
Range on Protein: 985-998 Range on HMM: 257-270/270 Sequence Identity: 42% (6 aa) PRDRPTMRDVVSML | ||||.......| PEDRPTFSEIHEQL |
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