Gene LRR8_d-1 (S.moellendorffii)

LRR8_d-1

Species: S.moellendorffii
Alias: LRR8_d-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_d-1.AA Protein None 1017 None Fasta, JSON
LRR8_d-1.NA RNA None 3054 None Fasta, JSON
LRR8_d-1.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of LRR8_d-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_d-1.AA LRRNT_2 73-112 43 7.4e-11 38.18 Pfam 1-46 (46) Show / Hide 
Range on Protein: 73-112
Range on HMM: 1-46/46
Sequence Identity: 43% (20 aa)

LLDDQHVLLLTKASLQ--DP-LEQLKGWTNR---SSICSWRGVTCD
. ||   ||  |.||.  || . .|. |..    |. |||.|||||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8_d-1.AA LRR_1 143-165 40 0.014177 13.3 Pfam 1-26 (26) Show / Hide 
Range on Protein: 143-165
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLTLLNLEN-N--NLQGWIPPQ-IANH
.|. |.| . |  ||.| |||  . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 167-190 32 0.971773 6.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 167-190
Range on HMM: 1-26/26
Sequence Identity: 32% (9 aa)

LLEELHLGG-N--PLAPASIPEQ-LCCL
 |..|.|.| |  .| .  ||.  .  |
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 192-213 29 0.270387 8.76 Pfam 1-26 (26) Show / Hide 
Range on Protein: 192-213
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLRVLELDS-S--NLHGSIPG--CYGN
.|..| |..    || |.||   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 216-238 33 0.318047 8.51 Pfam 1-26 (26) Show / Hide 
Range on Protein: 216-238
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RMEKLLLKE-N--FLTGPIPDS-LSRM
. ..| |   |   ||| ||.| .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 240-262 51 0.000903 17.54 Pfam 1-26 (26) Show / Hide 
Range on Protein: 240-262
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

ALQELDLAA-N--TLTGPIPPS-LGSL
 ||.|||   |   ||| |||| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 264-286 40 0.000393 18.82 Pfam 1-26 (26) Show / Hide 
Range on Protein: 264-286
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLRILYLWQ-N--QLSGRVPPH-LGNL
||..|.|   |  .|.| .||  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 288-309 25 45.621199 0.86 Pfam 1-26 (26) Show / Hide 
Range on Protein: 288-309
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

MLECFDVAN-N--GLGGELPR--ELKL
 |.  |. . |   | |..|     .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 311-333 29 0.051957 11.3 Pfam 1-26 (26) Show / Hide 
Range on Protein: 311-333
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RLENVSLAD-N--NFSGTIPAS-LGSS
.|.  .| . |  |..|.|| | . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 335-357 44 0.002156 16.2 Pfam 1-26 (26) Show / Hide 
Range on Protein: 335-357
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

LIRHLDLHD-N--NLTGEIPSG-VCQL
 ..|||| . |  ||||.||..   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 359-381 29 0.566879 7.62 Pfam 1-26 (26) Show / Hide 
Range on Protein: 359-381
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

DLQKIFLAT-N--KFEGEIPHC-LGAL
 ||.. |   |  ...|.||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 383-405 40 0.062317 11.02 Pfam 1-26 (26) Show / Hide 
Range on Protein: 383-405
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELEVIGFMK-N--NLSGSIPPS-FQHL
 |... .   |  ||.|.|||| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 407-429 40 0.004463 15.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 407-429
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLHILDVSE-N--NLSGAIPPE-LGMM
.| .||.|  |  ||.| |||. .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 431-453 40 0.00217 16.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 431-453
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLEVLFVHY-N--NLAGSIPPQ-LGNL
.|..| . . |  || |.|||  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 455-477 25 0.128132 9.91 Pfam 1-26 (26) Show / Hide 
Range on Protein: 455-477
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

LLKNFDVAY-N--RLEGVIPEE-LGGM
 |.  |. . |  .|.| ||.. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 479-502 25 7.913778 3.56 Pfam 1-26 (26) Show / Hide 
Range on Protein: 479-502
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ELSIFHLAS-N--KLTGKFPRLSMRDM
 | . .| . |  .|||..|  .   .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 504-526 37 0.420495 8.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 504-526
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

MLNLLDLSF-N--YLTGELPAV-LETS
 |  ||||  |   |||..|   .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 528-550 29 0.004237 15.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 528-550
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLVKLNLAS-N--RLSGTLPLQ-LGQL
.| .|.| . |  .|.|..|   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 552-574 33 0.004731 14.99 Pfam 1-26 (26) Show / Hide 
Range on Protein: 552-574
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLTDLDLSS-N--FFVGDVPAL-ISGC
||. ||||. |   ..|..|   . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 576-591 31 0.383953 8.22 Pfam 1-19 (26) Show / Hide 
Range on Protein: 576-591
Range on HMM: 1-19/26
Sequence Identity: 31% (6 aa)

SLTTLNLSR-N--SFQGRL
.|..|.||. |  ...| .
NLQHLDLSGCNCCNLTGHI
LRR_1 LRR8_d-1.AA LRR_1 598-620 29 0.159789 9.57 Pfam 1-26 (26) Show / Hide 
Range on Protein: 598-620
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

KLSIVDVSH-N--RLHGEIPLA-IGQS
.| . |.|. |  .| |.||   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-1.AA LRR_1 622-644 37 0.017565 12.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 622-644
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLLKLDLSY-N--DLSGSVPAF-CKKI
|| .||||. |   |.|..|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR8_d-1.AA TKL 738-994 20 1.3e-55 191.12 In-house 1-364 (364) Show / Hide 
Range on Protein: 738-994
Range on HMM: 1-364/364
Sequence Identity: 20% (78 aa)

ICRGR-NNVYKGVLKG---------GIRVAVKEVQSED--------------------------HSHVAEFDAEVA-TLGNIRHRNVVKLLASCTNKKS-
| .|.   ||||...|         |  ||||   |..                           |.  .|  |..  . ..|| |.|.....|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------HLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITGIAEGLAYLHHDYG-----PKVVHRDVKCDNILLDAEMK------------
            . .|.|..| |.|...||          |..|. .. .|| |..||| .       |...||| | .|||.|  ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PRLGDFGLAKLLREDKPSTASK------------------LAGTHGYIAPEYA-----YT-----------LKVDERADVYSFGIVVLEVLTGKMATW
  . ..||||.. . ... .....                    || .. |||       ||           .. .|..||||||||  |.||..    
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

RDATNDLDLVEWV---------KLMPVEELALEMG----------AEEQCYKLVLEIALACVEKSPSLRPTMQIVVDRL
     |..  ...         ..  .. | ...            ...| . . ...  | .  |. ||..| ...||
--PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR8_d-1.AA IRAK 733-929 34 4.4e-46 159.43 In-house 2-220 (317) Show / Hide 
Range on Protein: 733-929
Range on HMM: 2-220/317
Sequence Identity: 34% (76 aa)

SKDNLICRGR-NNVYKGVLKGGI-RVAVK----EVQSEDHSHVAEFDA---EVATLGNIRHRNVVKLLASCTNKKSHLLVYEFMPLGNLRDLLHGKMARS
.|||.|  |    ||.|..|.    .|||    .. ..  .|  .|..   |. ..  .|| |.| |.. ||    | |||..|| | |.| |..  .  
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

F--SLGWDKRVEIITGIAEGLAYLHHDYGPK--VVHRDVKCDNILLDAEMKPRLGDFGLAKL-----LREDKPS---TASKLAGTHGYIAPEYAY--TLK
    | | .|..|  |.| |. .|| . .|.  . |.|.|  |||||. . | ..||||.        .|. ..    .|.. ||  | .||. .  . .
PPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VDERADVYSFGIVVLEVLTG
   . ||||||||.||||||
LTKKTDVYSFGIVLLEVLTG
Kinase LRR8_d-1.AA TK 745-994 14 4.9e-40 131.4 In-house 18-486 (486) Show / Hide 
Range on Protein: 745-994
Range on HMM: 18-486/486
Sequence Identity: 14% (69 aa)

VYKGVLKGG--------------------------IRVAVKEVQSEDHSHVAEFDA--------------EVATLGNIR-----HRNVVKLLASCTNKKS
|||| ..|.                          ..|||| . ..|... .|| .              |.. .   .     | |.|.|.. || ...
VYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEP

------------HLLVYEFMPLGN----LRDLLHGKMARSFS----------------------------------------------------------
             ..| |.||.|.    ||| |. .  . .                                                           
KPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDL

--------------LGWDKRVEIITGIAEGLAYLHHD----YGPKVVHRDVKCDNILLDAEMK-----------PRLGDFGLAK-----LLREDKPSTAS
              |    .. .   ||.|..|||        ...||||. . |.|.. ...            ...||||..     | |.. ...  
LQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDY

KLAGTHG----------------------------YIAPEYAY---------TLKVDERADVYSFGIVVLEVLTGKMATWRD-ATN--------DLDLVE
  ....|                            . |||            . |  .  ||.|||... |..|   ...    .|        . ...|
YRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVME

WVKLM-------PVE--ELALEMGAEEQCY--------------KLVLEIALACVEKSPSLRPTMQIVVDRL
 ..         . .  .  ..| . ..|               ... .. . | .. |. |||.. ....|
YLRRGGRLCRSGL-NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_d-1.AA Pkinase 745-930 26 3.5e-37 132.56 Pfam 15-209 (293) Show / Hide 
Range on Protein: 745-930
Range on HMM: 15-209/293
Sequence Identity: 26% (54 aa)

VYKGVLKGG-IRVAVKEVQSEDHSHVAEFDA-----EVATLGNIRHRNVVKLLASCTNKKSHLLVYEFMPLG----NLRDLLHGKMARSFSLGWDKRVEI
|||.. ||  ..||||..  . | .  .  .     |.. . ...| |.|.|. ....|..  .| |... |     | |...... ..|.. ..    .
VYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY

ITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKP----RLGDFGLAKLLREDKPSTASKLAGTHGYIAPEYAY-TLKVDERADVYSFGIVVLEVLTG
.. |..||.|.|     ...|||.| .|||.| .. .    ...||||||.... . | .. ..|| .|.|||      . . ..|..|.|... |.|.|
MYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCG

K
.
R
Kinase LRR8_d-1.AA TKL-Unique 744-994 28 1.3e-34 119.56 In-house 12-290 (290) Show / Hide 
Range on Protein: 744-994
Range on HMM: 12-290/290
Sequence Identity: 28% (80 aa)

NVYKGVLKGGIRVAVKEVQ-SEDHS--HVAEFDAEVATLGNIR-HRNVVKLLASCT----NKKSHLLVYEFMPLGNLRDLLH------GKMARSFSLGWD
.||||. . |. ||.|     || |   . ||  || .. ... | |.|.. . |.      .   .| |..|.|.|.|.||         ...  | . 
QVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQ

KRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAE-----MKPRLGDFGLAKLLREDKPSTASKL--------AGTHGYIAPEYAYT--LKVDERA
.|| ..  || |. ||||  .| . ||| |  |.|.| .     .. .. ||||.|..  .  .|.. .         |.  ..|||       . .| .
QRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKS

DVYSFGIVVLEVLTGKM-ATWRDATNDLDLVEWVKLMPV--EELALEMGAEEQCYKLVLEIALACVEKSPSLRPTMQIVVDRL
||||||||. | .|.|   |..    ..|  .| ..  .  |.. .. .  . | |   ..  .|    || ||. . .. ||
DVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIP--NHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase LRR8_d-1.AA MLK 745-931 24 6.6e-32 108.02 In-house 15-234 (291) Show / Hide 
Range on Protein: 745-931
Range on HMM: 15-234/291
Sequence Identity: 24% (55 aa)

VYKGVLKGGI----RVAVKEVQSEDHSHVAE-------FDAEVATLGNIRHRN----VVKLLASCTNKKSH-LLVYEFMPLGNLRDLLHGKMA-------
|.||. .. .     ||||.| ..    ...       |. |.  |  ..|.|    ...... |..  .| ..| |... | | ..|||.         
VWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANH

---RSFSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDA------EMKPRLGDFGLAKLLREDKPSTASKLAGTHGYIAPEY---AYTLK
   ...    |  . . . .|.|..||| .  ....||| |  |||.|.      ... .  |||... . . . ..  . |||  . |||    .   |
NQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEK

VDERADVYSFGIVVLEVLTGKM
..| .||.|.|.|  |.||...
YSEKCDVWSWGVVLWEMLTREV
Kinase LRR8_d-1.AA RIPK 753-930 28 3e-30 100.25 In-house 18-225 (290) Show / Hide 
Range on Protein: 753-930
Range on HMM: 18-225/290
Sequence Identity: 28% (59 aa)

GIRVAVKEVQSED------HSHVAEFDAEVATLGNIRHRNVVKLLASCTNKKS------HLLVYEFMPLGNLRDLLHGKMA-RSFSLGWDKRVEIITGIA
| .||.| . .         . . .   |.. . ..|....|...  |  ..         .| |.|. |.| ..|| |.    . . |. |  .|  |.
GDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEIS

EGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRED--KP---------STASKLA-GTHGYIAPEYAY--TLKV----DERADVYSFGI
.|  || |. .| . ||| |  |||.|...   . |||||. ..    .          |..||.  ||. |..||       |     ..  |||||.|
CGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAI

VVLEVLTGK
|. ||||.|
VMWEVLTQK
Kinase LRR8_d-1.AA Dicty4 745-930 32 8.8e-30 96.63 In-house 15-214 (277) Show / Hide 
Range on Protein: 745-930
Range on HMM: 15-214/277
Sequence Identity: 32% (66 aa)

VYKGVLKGGIRVAVKEV--QSED--HSHVAEFDAEVATLGNIRHRNVVKLLASCT----NKKSHLLVYEFMPLGNLRDLLHG---KMARSFSLGWDKRVE
||||  . |. ||||      ..   .   || .||. ...||| |..... .||    .. . . | |.|| |||  |||        | .| |  .  
VYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKR

---IITGIAEGLAYLHH-DYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLREDKPSTA--SKLAGTHGYIAPEYAYTLKVDERADVYSFGIVVLEVL
   .   .| |...||  .  | ..||| | .|.| |. ..   .||||... ....  ..  .  .|| .. |||       .| |||||||||  | |
AMRMAFDAARGMNWLHCCN--PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEIL

TGK
|..
TRQ
Kinase LRR8_d-1.AA LISK 745-994 24 1.8e-29 92.76 In-house 10-296 (296) Show / Hide 
Range on Protein: 745-994
Range on HMM: 10-296/296
Sequence Identity: 24% (72 aa)

VYKGVLK-GGIRVAVKEVQS-----EDHSHVAEFDAEVATLGNIRHRNVVKLLASCTN-KKSHLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITG
|||| ..  |  .|.|. ..     .| .    .. ||... |.||.|.|.    | . ...  .| |..  |.|...|. .  ... | |..|| | ..
VYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPWPQRVKIALD

IAEGLAYLHHDYGPKVVHRDVKCDNILLDAE----MKPRLGDFGLAKLLREDK-----------------------------PSTASK----LAGTHGYI
||.|..|||     ...||| |  |.|..       . ...|||.|... ...                             ..   |      ||    
IACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTICGTPYWM

APEYAYTLKVDERADVYSFGIVVLEVLTGKMATW----RDA--TNDLDLVEWVKLMPVEELALEMGAEEQCYKLVLEIALACVEKSPSLRPTMQIVVDRL
|||     . ||..||.|||||..|  |.. |.     |..    .||. |  .... .          .| .  |.... |..  |. ||.   .|..|
APEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPD----------DCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase LRR8_d-1.AA STE 745-930 20 3.3e-29 100.34 In-house 15-265 (359) Show / Hide 
Range on Protein: 745-930
Range on HMM: 15-265/359
Sequence Identity: 20% (53 aa)

VYKGVLKG----------------GIRVAVKEVQSED-----------------HSHVAEFDAEVATLGNIR--HRNVVKLLASCTNK-------KSHLL
|||.. .                 | ..|.|..  |.                 |. . ..  |. .. . .  | |.|| . .. ..        .  .
VYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWI

VYEFMPLGNLRDLLHGKMARSFSLG----------WDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLREDKP-----
. |.|. | |.|... |. . ..|            .    |.  | .|| |..|. .  ..|||.|..||||       | |||... | .. .     
CMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSN

-------STASK---LAGTHGYIAPEYAYT------LKVDERADVYSFGIVVLEVLTGK
       ....|   ..||  . |||           . |...|..|.|....| .|||
NIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LRR8_d-1.AA Pkinase_Tyr 744-885 28 4e-27 92.48 Pfam 14-164 (270) Show / Hide 
Range on Protein: 744-885
Range on HMM: 14-164/270
Sequence Identity: 28% (44 aa)

NVYKGVLK-----GGIRVAVKEVQSEDHSHV----AEFDAEVATLGNI-RHRNVVKLLASCT-NKKS--HLLVYEFMPLGNLRDLLHGK--MARSFSLGW
.||||..|     ..| |||| .  |...|     ..| .|.... .. .| |.|.|.. ||  ...  ...| |.||.|.|.| |. .    ..... .
EVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

DKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRED
   ... . ||.|..||.     . .|||. . |.|.. ... . .|||||... .|
--LLQMCWQIAKGMEYLESK---NCIHRDLAARNCLVTENNVVKICDFGLARDIYND
Kinase LRR8_d-1.AA DRK 753-928 31 1.9e-26 86.64 In-house 22-197 (258) Show / Hide 
Range on Protein: 753-928
Range on HMM: 22-197/258
Sequence Identity: 31% (56 aa)

GIRVAVKEVQS--ED-HSHVAEFDAEVATLGNIRHRNVVKLLASCTNKKSHLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITGIAEGLAYLHHDY
|. ||||      ..    . ||  |.  . . || |..  . .|.|  . . . |.||.| |   ||     | .. |  .  .   .| |. |||   
GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH---DESIEMDWPLMKQMMFDCAKGMIYLHC-C

GPKVVHRDVKCDNILLDAEMKPRLGDFGLAK-LLREDKPSTASKLAGTHGYIAPEYAYTLKVDERADVYSFGIVVLEVLT
 | ..||| | .| | |   .    ||||.    .     .|    || . .|||        | ||||||.||  |..|
NPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase LRR8_d-1.AA TyrKc 738-994 23 6e-25 90.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 738-994
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

ICRGRN-------NVYKGVLKGGIRVAVKEVQSEDHSHVAEFDAEVATLGNI--RHRNVVKLLASCTNK-------KSHLLVYEFMPLGNLRDLLHGKMA
|  |.         ||||..|  | |||| ....    ...|  |   . ..  .| |.|.|.. || .       . ...| |.||.|.|.| |. .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RSFSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRED------KPSTASKL-AGTHG-----YIAPEYAYTLK
.   | ... ... . ||.| .|||.    ...|||  . |.|....   . .||||.. . .|      |    .|   |...       |||   . |
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VDERADVYSFGIVVLEVLTGKMATWRDA----TNDLDLVEWVK---LMPVEELALEMGAEEQ----CYKLVLEIALACVEKSPSLRPTMQIVVDRL
  .  ||.|||..  |..|  .  . .      .. ...|.||    ||  . ..    .      | . . .| . | .  |. |||.. .....
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc LRR8_d-1.AA S_TKc 732-995 21 3.8e-23 84.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 732-995
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

ESKDNLICRGRN-NVYKGVLKG-GIRVAVKEVQSEDHSHVAEFDAEVATLGNIRHRNVVKLLASCTNKKSHLLVYEFMPL--GNLRDLLHGKMA----RS
  . ..| .|    |||.. |. | .||.|..          .  |.. | . .| |.|||. .. . ..  .| |...   |.|.|... .      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLREDKPSTASKLAGTHGYIAPEYAYTLKVDE-RADVYSFGIV
|.  .     ..  |...|.|.|     ...|||.| .|||||      ..|||||..|        . . ||  |.|||     . .  ..|..|.|..
FPE-H--ARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

VLEVLTGKMATWRDATNDLDLVEWVKLMPVEELALEMGAEEQCYKLVLEIALACVEKSPSLRPTMQIVV-------DRLN
. | |.|.   .    ..  . . ..                  . ....   | .| |. ||| ..         .   
LYEMLCGYPPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase LRR8_d-1.AA DRK 976-996 38 0.000851 8.78 In-house 238-258 (258) Show / Hide 
Range on Protein: 976-996
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CVEKSPSLRPTMQIVVDRLNG
| .  |. ||.|| .. ||  
CWNEDPQHRPSMQECLERLEA
Kinase LRR8_d-1.AA Dicty4 976-996 26 0.009194 5.24 In-house 255-277 (277) Show / Hide 
Range on Protein: 976-996
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CVEKSPSLRPTMQIVVDR--LNG
| ...|. ||... .. |  |. 
CWDHDPQHRPSFEEIIQRRILEH
Kinase LRR8_d-1.AA Pkinase_Tyr 971-994 25 0.828784 3.36 Pfam 247-270 (270) Show / Hide 
Range on Protein: 971-994
Range on HMM: 247-270/270
Sequence Identity: 25% (6 aa)

EIALACVEKSPSLRPTMQIVVDRL
.. . | .. |. |||.. .. .|
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR8_d-1.AA Pkinase_Tyr 915-931 44 3.698087 1.16 Pfam 196-213 (270) Show / Hide 
Range on Protein: 915-931
Range on HMM: 196-213/270
Sequence Identity: 44% (8 aa)

DVYSFGIVVLEVLT-GKM
||.|||..  |..| |..
DVWSFGVLMWEIFTYGEQ