Gene LRR8_s-2 (S.moellendorffii)
LRR8_s-2
Species: S.moellendorffii
Alias: LRR8_s-2
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LRR8_s-2.AA | Protein | None | 1035 | None | Fasta, JSON |
| LRR8_s-2.NA | RNA | None | 3108 | None | Fasta, JSON |
| LRR8_s-2.kin_dom | Protein Kinase Domain | None | 214 | None | Fasta, JSON |
Protein domains of LRR8_s-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRRNT_2 | LRR8_s-2.AA | LRRNT_2 | 42-82 | 36 | 7e-12 | 41.5 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 42-82 Range on HMM: 1-46/46 Sequence Identity: 36% (17 aa) GSDQVVAMLALKSGIVDRYDR----LASWKSSD--KSPCGWEGVECV .|.. | ||.||...| .|. |.||..|. ..| |.||.| HNDDGQALLAFKSSLND-SDPHHGVLSSWNPSSSDSDCCSWTGVTCD |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 135-158 | 29 | 0.296121 | 8.62 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 135-158 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) NLVSLELQR-N-PSMGGALPAN-LSAL || .| |.. | ... | .| . . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 160-182 | 44 | 0.003602 | 15.41 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 160-182 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) LLQHLDLSF-D--PFTGTIPEE-LGGL ||||||| ..||.||.. . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 184-206 | 40 | 0.008163 | 14.15 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 184-206 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) NLQRLLLWSC---KLEGPLPSS-IGEL |||.| | .| .|.| .|.| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 208-230 | 40 | 0.011592 | 13.61 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 208-230 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) SLTNLTLSY-N--NLGPELPES-LRNL .|. | ||. | || ...|.| . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 232-254 | 37 | 0.037309 | 11.81 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 232-254 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) TLQSLKCGGC---GLSGRIPSW-LGDL .||.| .|| |.| ||.. . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 256-278 | 33 | 0.037796 | 11.79 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 256-278 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) KLDFLELTY-N--SLSGDIPVA-ILGL .| | | . | .|.|.|| . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 280-302 | 37 | 0.023224 | 12.54 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 280-302 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) KLTKLELYN-N--LLTGGIPRE-IAGL .|..| | . | ||| || . . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 304-326 | 37 | 0.000983 | 17.41 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 304-326 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLTDLDLSS-N--SLSGSIPEE-IASI .|. ||||. | .|.|.||.. . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 328-350 | 33 | 0.997345 | 6.75 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 328-350 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) GLALIHLWN-N--SLTGAVPRG-IANL | ..| . | .||| .| . . || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 352-374 | 33 | 10.394168 | 3.14 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 352-374 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) ALYDVGLFQ-N--RLTGKLPPD-MGSL | | | .|||..||. .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 376-395 | 46 | 0.008006 | 14.18 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 376-395 Range on HMM: 1-26/26 Sequence Identity: 46% (12 aa) SLQIFDVSS-N--NLSGEIPR---NL .||. |.|. | ||.|.|| || NLQHLDLSGCNCCNLTGHIPPSCFNL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 400-422 | 29 | 0.815494 | 7.06 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 400-422 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) RLWRLMLFQ-N--SFSGGIPPE-LGSC .| .| | | ...| |||. . .. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 424-443 | 30 | 8.174862 | 3.51 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 424-443 Range on HMM: 1-26/26 Sequence Identity: 30% (8 aa) SLIRVRIFG-N--SLSGAVPP---GL .| . . | | .|.| .|| .| NLQHLDLSGCNCCNLTGHIPPSCFNL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 448-470 | 29 | 6.772021 | 3.8 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 448-470 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) LMVILDISD-N--QLEGAIDPA-IAKS .||.|. | .|.| | | . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 472-494 | 33 | 0.472634 | 7.9 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 472-494 Range on HMM: 1-26/26 Sequence Identity: 33% (9 aa) RLEMLRIFG-N--QLGGELPRS-MGRL .|. | . | | .| |..| | | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 496-518 | 37 | 0.001414 | 16.85 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 496-518 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLNQLNASG-N--QLTGSIPSE-IAQC .| |. || | .|||.||.. . .. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 520-542 | 37 | 0.002008 | 16.31 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 520-542 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLTYLFLDG-N--KLQGPIPGE-IGEL .|..| |.| | .|.| || . . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 544-566 | 37 | 0.001752 | 16.52 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 544-566 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RLQYLSLAR-N--SLSGSIPGE-VGEL .||.|.| . | .|.|.|| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 568-590 | 48 | 3.8e-05 | 22.43 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 568-590 Range on HMM: 1-26/26 Sequence Identity: 48% (13 aa) NLISLDLSE-N--QLSGRIPPE-LGKL || .|||| | .|.| |||. . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| LRR_1 | LRR8_s-2.AA | LRR_1 | 594-616 | 25 | 1.946774 | 5.72 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 594-616 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) EFTHFNVSY-N--RLTGSVPFD-VNSA .| ..|. | .|||..| . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
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| Kinase | LRR8_s-2.AA | TKL | 731-1008 | 23 | 9.3e-57 | 194.87 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 731-1008
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)
IGCGGAGKVYKASLKN---------GQCLAVKKLWSSSGGKDTTSSSG------------------WDYG-FQAEIESLGRIRHVNIVRLLCCCSNGET-
|| || |.|||. ... |. ||||. | . ..| .| | . || .. |.|| |||... .| ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------NVLVYDYMPNGSLGDLLHSKKGGVLDWSARYRAALGAAHGLAYLHHDCV-----PQILHRDVKSNNILLSEDFD--------------
.|..|.|.||| ..|| |. | | ||..| |..||| . |.|.||| ||.|||. |..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC
GLLADFGLARLLEGSSSGENGG-----------GYSVSSLPG-SLGYIAPEYA----------------HKLKVNEKSDIYSYGVVLLELLTGRRPVDAG
..||||.| ...|.. . .. . . .. .. .... ||| .... .||.|.||.|.|| |.||..|| .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY
FGDDGM------DIVRWVCAKIQ--SRDDVIK-VFDPRIVGASPRDMMLVLKIALHCTSEVPANRPSMREVVRML
.. . .. .|| | . .... . .. . . | . . |.. .| .. | .|||. |.. |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | LRR8_s-2.AA | IRAK | 726-940 | 37 | 1.4e-50 | 174.4 | In-house | 2-225 (317) | Show / Hide |
Range on Protein: 726-940 Range on HMM: 2-225/317 Sequence Identity: 37% (86 aa) DEDNVIGCGGAGKVYKASLKNGQ-CLAVKKLWSSSGGKDTTSSSGWDYGFQA---EIESLGRIRHVNIVRLLCCCSNGETNVLVYDYMPNGSLGDLLHSK ..||.|| || | ||.. .|| ||||| . .| . . ||. |.... |.|| ||| |. |. .. |||.||||||| | |. HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKE----MADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQ KG-GV---LDWSARYRAALGAAHGLAYLHHDC--VPQILHRDVKSNNILLSEDFDGLLADFGLARLLEGSSSGENGGGY---SVSSLPGSLGYIAPEYAH .| . | | | ..|.| |. .|| . .| | |.|.|| |||| ..| ..||||.| |. . | .| . |.. | .||. DGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPII-HGDIKSANILLDQHFTPKICDFGLHRFGH-PASHKEKQTYTCMMTSHVRGTTWYMPPEFIR --KLKVNEKSDIYSYGVVLLELLTGRRPVD . . |.|.|| |.||||.|||.|.|. DPQGQLTKKTDVYSFGIVLLEVLTGCRAVY |
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| Kinase | LRR8_s-2.AA | MLK | 725-938 | 27 | 7.9e-37 | 125.33 | In-house | 1-235 (291) | Show / Hide |
Range on Protein: 725-938 Range on HMM: 1-235/291 Sequence Identity: 27% (67 aa) LDEDNVIGCGGAGKVYKASLKNGQ----CLAVKKLWSSSGGKDTTSSSGWDYGFQAEIESLGRIRHVN----IVRLLCCCSNGETN-VLVYDYMPNGSLG ... .|| |. |||.|. .| .|||. . .. | ... . |. |.. | ...| | |.... .|.. . . ..| |...||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKR-VRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY DLLHSKKG------------GVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSE------DFDGLLADFGLARLLEGSSSGENGGGYS-V ..||.... .| | . . || |.|..||| . ...| ||| || |||..| . . .|||..| . . . . NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQM-------C-TNM SSLPGSLGYIAPEY---AHKLKVNEKSDIYSYGVVLLELLTGRRP | .|.. . ||| . |..||.|..|.|||| |.||.. | MSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
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| Pkinase | LRR8_s-2.AA | Pkinase | 725-936 | 24 | 1.3e-35 | 126.96 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 725-936 Range on HMM: 1-209/293 Sequence Identity: 24% (57 aa) LDEDNVIGCGGAGKVYKASLKNGQC-LAVKKLWSSSGGKDT------TSSSGWDYGFQAEIESLGRIRHVNIVRLLCCCSNGETNVLVYDYMPNG----S . .|| |. |.|||. |. .. |||... .. .. . .||. . |..| |||||.... .. .| .|...| . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMD LGDLLHSKKGGVL--DWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDG----LLADFGLARLLEGSSSGENGGGYSVSSLPGSLGYIA | |... ...|.. .. . .. . ||.|.| |.|||.|. |||.... . ..|||||.... . . ... |...|.| LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMA PEYAH-KLKVNEKSDIYSYGVVLLELLTGR || . |.|..|.|..| |.|.|| PEVIRGGQYYGPKVDMWSCGCILYEMLCGR |
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| Kinase | LRR8_s-2.AA | S_TKc | 725-1015 | 21 | 4.5e-34 | 120.42 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 725-1015 Range on HMM: 1-231/231 Sequence Identity: 21% (66 aa) LDEDNVIGCGGAGKVYKASLKN-GQCLAVKKLWSSSGGKDTTSSSGWDYGFQAEIESLGRIRHVNIVRLLCCCSNGETNVLVYDYMPN--GSLGDLLHSK . ..|| |. |||||. |. |. |.|.. .. ||. | . .| |||.|. .. . . .| .|... |.| |..... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR KG------GVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGLLADFGLARLLEGSSSGENGGGYSVSSLPGSLGYIAPEYAHKLK .. . ..| . . .|.|.| .|.|||.| ||||.| ..||||||.| ... |.. |.||| . GRHGLRFPFPE-HARFY--MYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---G VNE-KSDIYSYGVVLLELLTGRRPVDAGFGDDGMDIVRWVCAKIQSRDDVIKVFDPRIVGASPRDMMLVLKIALHCTSEVPANRPSMREVVR--MLKDVD . |.|..| |..| |.|.|. | . . . . . .. . . . .| |..||. |. . .. . YGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCH PSL | . PWF |
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| Kinase | LRR8_s-2.AA | TKL-Unique | 729-938 | 28 | 3.7e-32 | 110.78 | In-house | 3-233 (290) | Show / Hide |
Range on Protein: 729-938
Range on HMM: 3-233/290
Sequence Identity: 28% (69 aa)
NVIGCGGAGKVYKASLKNGQCLAVKKLW-SSSGGKDTTSSSGWDYGFQAEIESLGRIR-HVNIVRLLCCCS----NGETNVLVYDYMPNGSLGDLLHS--
|.|| ||.|.|||. .| |.|.. .. .. . | |. . ... | |||.. | .| .|.| ||| |.||
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQE------FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN
------KKGGVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSED-----FDGLLADFGLARLLEGS---SSGEN-GGGYSVSSLPGSLGY
.. |... |.. |. .| |. |||| | |.||| || |.|.... . ..||||.... . ...|. |.. .. ||. .
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTR--NQTRCGSFRW
IAPEYAHK--LKVNEKSDIYSYGVVLLELLTGRR------P
.||| . .||||.||.|.|| |..|. . |
MAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
|
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| Kinase | LRR8_s-2.AA | RIPK | 731-938 | 29 | 8.8e-31 | 102.11 | In-house | 1-227 (290) | Show / Hide |
Range on Protein: 731-938
Range on HMM: 1-227/290
Sequence Identity: 29% (68 aa)
IGCGGAGKVYKASLKNGQCLAVKKLWSSSGGKDTTSSSGWDYGFQAEIESLGRIRHVNIVRLLCCCSNGET------NVLVYDYMPNGSLGDLLHSKKG-
.| || |.|.|| . ..|| . . . . | . . ..|. .||... | | .| ||.|||| ..||.|
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPY
--GVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGLLADFGLARLLEGSSSGENGG----GYSVSSLP--GSLGYIAPEYAH--K
. |. | | . | || |. | |.||| | |||. .| .|||||| ...|.|. .|| |.. | | |..||
QHHPDPWPLRCRMIHEISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN
LKV----NEKSDIYSYGVVLLELLTGRRP
| ..|.|.||...|. |.||.. |
KKPIKVVTPKYDVYSFAIVMWEVLTQKHP
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| Kinase | LRR8_s-2.AA | Dicty4 | 725-938 | 31 | 1.6e-26 | 85.57 | In-house | 1-216 (277) | Show / Hide |
Range on Protein: 725-938 Range on HMM: 1-216/277 Sequence Identity: 31% (72 aa) LDEDNVIGCGGAGKVYKASLKNGQCLAVKKLWSSSGG--KDTTSSSGWDYGFQAEIESLGRIRHVNIVRLLCCCS----NGETNVLVYDYMPNGSLGDLL .. .. || |. |.|||.. . |. ||||| . . .. .. | .|.. .. ||| ||. .. | . .. . | ||| |.| || INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNE------FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL HS-----KKGGVLDWSARYR---AALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGLLADFGLAR-LLEGSSSGENGGGYSVSSLPGSLGYIAPE |. .. |||. . | |. || |...|| | | |.||| || |.| .... .||||.. .... . | .. |. .. ||| HDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDN-----QMTACGTPCWMAPE YAHKLKVNEKSDIYSYGVVLLELLTGRRP . |||.| ||.| || |.||. | VMMHQPYNEKADVYSFGIVLWEILTRQEP |
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| Kinase | LRR8_s-2.AA | TK | 725-938 | 16 | 4.1e-26 | 83.89 | In-house | 1-394 (486) | Show / Hide |
Range on Protein: 725-938
Range on HMM: 1-394/486
Sequence Identity: 16% (65 aa)
LDEDNVIGCGGAG---KVYKASLKNG--------------------------QCLAVKKLWSSSGGKDTTSSS-------GWDYG-----FQAEIESLG-
. ...| | | .|||. .... . ||| | . .. .. | | . .|.. .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDG---GEDFLEEAEEMKMMCH
-RIRHVNIVRLLCCCSNGET------------NVLVYDYMPNGS----LGDLLHSKKGG-----------------------------------------
.| |||||. .|. ||. .| |||.|. | | |......
SLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEE
---------------------------------VLDWSARYRAALGAAHGLAYLHHD----CVPQILHRDVKSNNILLSEDFD-----------GLLADF
|. . .. .| |..||| ... |||. |.|..|. .|||
QDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADF
G--------LARLLEGSSSGENGGGYSVSSLPGS---------------LG-----YIAPEYAH---------KLKVNEKSDIYSYGVVLLELLT-GRRP
| ||| .. .. ..|... .. | . ||| . | .|||..|.||.. |..| |. |
GLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
|
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| Kinase | LRR8_s-2.AA | STE | 725-938 | 21 | 6.9e-25 | 84.88 | In-house | 1-267 (359) | Show / Hide |
Range on Protein: 725-938 Range on HMM: 1-267/359 Sequence Identity: 21% (60 aa) LDEDNVIGCGGAGKVYKASLKN----------------GQCLAVKKLWSSSGGKDTTS---------SSGWDY-GFQAEIESLGRIR--HVNIVRLLCCC .. .|| |. |.|||| .. |. |.|.. .. . . . . .. ||. . . . | |||. ..|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY SNG-------ETNVLVYDYMPNGSLGDLLHSKKGGV--------------LDWSARYRAALGAAHG-LAYLHHDCVPQILHRDVKSNNILLSEDFDGLLA .. .. .. ||..||| |....|.| .. |.. . .| |.||| | |||.|. |||| |. FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYI--CRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLC DFGLARLLEGSSSGENGGG-------YSVS----SLPGSLGYIAPEYAHK------LKVNEKSDIYSYGVVLLELLTGRRP |||.. |. |... . . .. . .. |. . ||| . . ..|.||.| | ...|..||. | DFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP |
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| Kinase | LRR8_s-2.AA | LRRK | 804-940 | 31 | 6.2e-23 | 77.95 | In-house | 132-284 (351) | Show / Hide |
Range on Protein: 804-940 Range on HMM: 132-284/351 Sequence Identity: 31% (53 aa) LVYDYMPNGSLGDLLHSKK-GG------VLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGL------------LADFGLAR---- .| .|.|.|.| ..||.|| | ...|. ... || | |..|| |.. | |.||| || |||| . .. .||||. | MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQC LLEG--SSSGENGGGYSVSSLPGSLGYIAPEYAHK---LKVNEKSDIYSYGVVLLELLTGR-RPVD ...| . ...| |. ||| . .||.|.||.|..| ||||.. .| | FHMGVAKGCVGN------------PGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD |
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| Kinase | LRR8_s-2.AA | Pkinase_Tyr | 725-938 | 27 | 4.3e-19 | 65.29 | Pfam | 1-214 (270) | Show / Hide |
Range on Protein: 725-938 Range on HMM: 1-214/270 Sequence Identity: 27% (64 aa) LDEDNVIGCGGAGKVYKASLK-----NGQCLAVKKLWSSSGGKDTTSSS--GWDYGFQAEIESLGRI-RHVNIVRLLCCCS-NGET--NVLVYDYMPNGS . . ..| | |.|||. .| ... |||.| ..... | | .|.. . . .| |||||. .|. || .| |||.|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCRED--FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD LGDLLHSK--KGGVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGLLADFGLARLLEGSSSGENGGGY-SVSS-LPGSLGYIAPE | | |... .. |. . .. | |..||. . |||. |.|..|.. .||||||.. .| . | ... . ||| LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI------YNDDYYYRKRGGGKLPIKWMAPE YAHKLKVNEKSDIYSYGVVLLELLT-GRRP . | ..|||..|.||.. |..| |. | CINYGKFTTKSDVWSFGVLMWEIFTYGEQP |
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| Kinase | LRR8_s-2.AA | TyrKc | 725-1008 | 24 | 9.6e-18 | 64.2 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 725-1008 Range on HMM: 1-280/280 Sequence Identity: 24% (73 aa) LDEDNVIGCGGAGKVYKASLKNGQCLAVKKLWSSSGGKDTTSSSGWDYGFQAEIESLGRI--RHVNIVRLLCCCSNG-------ETNVLVYDYMPNGSLG . . ..|.| |.|||. .| . |||.| ... | |.. . .. .| |||||. .|. . | .| |||.|.| ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK DLLHSKKGGVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLSEDFDGLLADFGLARLLEGS-SSGENGGGYSVS---SLP--GSLGYIAPE | |..... | .. .. .| | .|||. .. ||| |.|..|.. .||||.| .. ..||.. |... . . ||| DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE YAHKLKVNEKSDIYSYGVVLLELLT-GRRPVDA-GFGDDGMDIVRWVCAKIQSRDDVIKVFD--PRIVGASPRDMMLVLKIALHCTSEVPANRPSMREVV . | ..|||..|.||.. |..| | | . | . | ....... . . | . ... . .| . | | |..||...|.. CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYP-MS--FVCCPDEMYQIMKQCWHEDPEDRPTFSEIH RML . . ECF |
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| Kinase | LRR8_s-2.AA | LISK | 812-895 | 25 | 1.5e-16 | 50.06 | In-house | 82-182 (296) | Show / Hide |
Range on Protein: 812-895 Range on HMM: 82-182/296 Sequence Identity: 25% (27 aa) GSLGDLLHSK--KGGVLDWSARYRAALGAAHGLAYLHHDCVPQILHRDVKSNNILLS----EDFDGLLADFGLARLLEGSS--------------SGENG | | ..|... . .| |. | . ||. | |..||| . |.||| ||.|.|.. ... ..|||.||... .. ..|. GDLHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDND GGYS .... MPMK |
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| Kinase | LRR8_s-2.AA | LISK | 917-938 | 36 | 5.9e-07 | 18.43 | In-house | 217-238 (296) | Show / Hide |
Range on Protein: 917-938 Range on HMM: 217-238/296 Sequence Identity: 36% (8 aa) NEKSDIYSYGVVLLELLTGRRP .|..|..|.|.||.|. |.... DESCDVFSFGIVLCEIITRVKA |
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| Kinase | LRR8_s-2.AA | LRRK | 989-1010 | 31 | 0.000128 | 12.25 | In-house | 330-351 (351) | Show / Hide |
Range on Protein: 989-1010 Range on HMM: 330-351/351 Sequence Identity: 31% (7 aa) HCTSEVPANRPSMREVVRMLKD || .. | .||.. ..| |.. HCWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | LRR8_s-2.AA | TK | 986-1008 | 21 | 0.000129 | 10.55 | In-house | 464-486 (486) | Show / Hide |
Range on Protein: 986-1008 Range on HMM: 464-486/486 Sequence Identity: 21% (5 aa) IALHCTSEVPANRPSMREVVRML . . | .. |. ||........| LMQQCWHYDPEDRPTFSQLHEQL |
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| Kinase | LRR8_s-2.AA | LRRK | 725-755 | 22 | 0.000143 | 12.07 | In-house | 1-59 (351) | Show / Hide |
Range on Protein: 725-755 Range on HMM: 1-59/351 Sequence Identity: 22% (13 aa) LDEDNVIGCGGAG-KVYKASLKN---------------------------GQCLAVKKL | . . || || | .||.| ... .| |.||. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW |
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| Kinase | LRR8_s-2.AA | MLK | 990-1008 | 42 | 0.000724 | 9.45 | In-house | 273-291 (291) | Show / Hide |
Range on Protein: 990-1008 Range on HMM: 273-291/291 Sequence Identity: 42% (8 aa) CTSEVPANRPSMREVVRML | .. |..|||.|..| | CWNQDPHKRPSFRQIVQHL |
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| Kinase | LRR8_s-2.AA | LISK | 730-755 | 44 | 0.004 | 5.77 | In-house | 1-27 (296) | Show / Hide |
Range on Protein: 730-755 Range on HMM: 1-27/296 Sequence Identity: 44% (12 aa) VIGCGGAGKVYKASLK-NGQCLAVKKL .|| |. ||||| ... || |.|.. EIGKGFFGKVYKGTHRQTGQVMAIKMI |
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| Kinase | LRR8_s-2.AA | LISK | 984-1008 | 40 | 0.005749 | 5.25 | In-house | 272-296 (296) | Show / Hide |
Range on Protein: 984-1008 Range on HMM: 272-296/296 Sequence Identity: 40% (10 aa) LKIALHCTSEVPANRPSMREVVRML |.....|.. | |||| |.|. | LDLCFDCCKYDPKNRPSFKEIVQWL |
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| Kinase | LRR8_s-2.AA | Dicty4 | 990-1010 | 30 | 0.058958 | 2.51 | In-house | 255-277 (277) | Show / Hide |
Range on Protein: 990-1010 Range on HMM: 255-277/277 Sequence Identity: 30% (7 aa) CTSEVPANRPSMREVVRM--LKD | .. | .|||. |.. | CWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | LRR8_s-2.AA | IRAK | 987-1008 | 27 | 0.096119 | 2.16 | In-house | 296-317 (317) | Show / Hide |
Range on Protein: 987-1008 Range on HMM: 296-317/317 Sequence Identity: 27% (6 aa) ALHCTSEVPANRPSMREVVRML |. |. . ..|..|..|. | ACCCGHHRANRRCDMAWVMQQL |
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| Kinase | LRR8_s-2.AA | Pkinase_Tyr | 995-1008 | 35 | 0.151456 | 5.86 | Pfam | 257-270 (270) | Show / Hide |
Range on Protein: 995-1008 Range on HMM: 257-270/270 Sequence Identity: 35% (5 aa) PANRPSMREVVRML |..||...|....| PEDRPTFSEIHEQL |
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