Gene LRR8x_d (S.moellendorffii)

LRR8x_d

Species: S.moellendorffii
Alias: LRR8x_d
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8x

Sequence

Name Sequence Type Origin Length Description Download
LRR8x_d.AA Protein None 825 None Fasta, JSON
LRR8x_d.NA RNA None 2478 None Fasta, JSON
LRR8x_d.kin_dom Protein Kinase Domain None 115 None Fasta, JSON

Protein domain

Protein domains of LRR8x_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8x_d.AA LRRNT_2 22-64 34 1.7e-05 20.76 Pfam 1-46 (46) Show / Hide 
Range on Protein: 22-64
Range on HMM: 1-46/46
Sequence Identity: 34% (16 aa)

AMKDAYSLLQFRSTIWN-DT-YMSLRNWYLSF-SGDACSWKGVSCS
.  |. .||.|.| . . |    .|..|  |  ..| |||.||.|.
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8x_d.AA LRR_1 92-114 33 0.013547 13.37 Pfam 1-26 (26) Show / Hide 
Range on Protein: 92-114
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ELTVLDLSN-N--SFMGGIPTQ-ISRC
 |..||||. |  .. | ||   .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 116-138 21 53.29821 0.62 Pfam 1-26 (26) Show / Hide 
Range on Protein: 116-138
Range on HMM: 1-26/26
Sequence Identity: 21% (6 aa)

ELTEFNVAY-N--LLT-ADVPLE-LGFL
 |.. .. . |   ||   .| . .  |
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 140-162 40 0.001918 16.38 Pfam 1-26 (26) Show / Hide 
Range on Protein: 140-162
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

KLKVLRIND-N--NLYGILPPT-FSNL
.|..| ... |  || | .||  | ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 164-186 28 31.526027 1.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 164-186
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

HLAHLSVAG-N--MLSGYPFET--ISIL
.| ||.. | |   |.|. .    .  |
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 188-235 21 0.16722 9.5 Pfam 1-26 (26) Show / Hide 
Range on Protein: 188-235
Range on HMM: 1-26/26
Sequence Identity: 21% (11 aa)

NLEFLDLSS-N--KFKGSVLNQTVVNWPKLAKFIARANNFDNVLPAT-LGNL
||. ||||. |  .. |.                         .|   . ||
NLQHLDLSGCNCCNLTGH-------------------------IPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 237-259 33 0.00057 18.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 237-259
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALQELDISQ-N--SIQGTIPDK-INKC
 ||.||.|  |  ...|.||.  . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 261-283 33 0.226902 9.03 Pfam 1-26 (26) Show / Hide 
Range on Protein: 261-283
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLVIMNLSC-N--ALSGAIPSA-VGEI
|| . .||. |   |.| ||.      
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 285-307 21 10.062235 3.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 285-307
Range on HMM: 1-26/26
Sequence Identity: 21% (6 aa)

TLSVLDLRA-N--SFN-SGLPTG-INGY
.| .|||.  |  ..  . .| . . . 
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 309-330 33 0.049648 11.37 Pfam 1-26 (26) Show / Hide 
Range on Protein: 309-330
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLVRLQVSR-N--NFL-AIPDD-LATL
|| .| .|. |  |.   ||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 332-354 29 0.524382 7.74 Pfam 1-26 (26) Show / Hide 
Range on Protein: 332-354
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

NILDVDISQ-N--HLEGVIPST-LGTM
|.   |.|  |  .|.| ||.  .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 356-378 28 0.534698 7.71 Pfam 1-26 (26) Show / Hide 
Range on Protein: 356-378
Range on HMM: 1-26/26
Sequence Identity: 28% (8 aa)

RVLSLNFSY-N--NLS-SNIPPQ-IGDC
.  .|..|. |  ||. . |||  .  .
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 380-402 33 0.339386 8.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 380-402
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLSVLDLSH-N--LL-KEIIPYTIIKM
.| .||||. |   | ..| | .. ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 404-426 37 0.000237 19.6 Pfam 1-26 (26) Show / Hide 
Range on Protein: 404-426
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLECLNLSE-N--HLSGRLPEE-FGYL
.|. |.||  |  .|.| .|.. |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 428-450 37 0.057272 11.15 Pfam 1-26 (26) Show / Hide 
Range on Protein: 428-450
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

ELTELDVSG-N--AIGGTIPAA-IGTL
 |..||.|| |   . |.||   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8x_d.AA LRR_1 452-471 42 0.060327 11.07 Pfam 1-26 (26) Show / Hide 
Range on Protein: 452-471
Range on HMM: 1-26/26
Sequence Identity: 42% (11 aa)

RLTFLDLAF-N--KLSGIIPT---NL
.|. |||   |  .|.| ||    ||
NLQHLDLSGCNCCNLTGHIPPSCFNL
Kinase LRR8x_d.AA TKL 566-816 16 1.5e-34 121.09 In-house 1-364 (364) Show / Hide 
Range on Protein: 566-816
Range on HMM: 1-364/364
Sequence Identity: 16% (63 aa)

IGSSALCTVYKAELSD---------GLEVAVKVLSPEY--------------------------YGSNRRSFSMEAKMFAKVLHPNIVKVVGCCNSVNM-
||| . ..|||...           | .||||... ..                          .  .|  .  |..|  .  |||||. .|.|.. .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VALVSELMPNGSLEKHLYAGEVCDLTWIQRLDIILGIAEAVAYMHHEW------ESLLWCDFRTRSILLDALFK--------------
             ..| |..|.|||. .|         | ||....|.|| ...|.| ..        .. .|  .. ||.|  ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PHISNYRIAGNPSSEE---------------------NLPPA--------EYMFSSIRTREG----------------DVFSYGVLILEVLTRISPQGDV
. |. . .. . | ..                     . ..         | .  .. ..|                 ||.|.|... |.|||  |  | 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

S---WQGGLALWVQQFYPTTLSDILDPQIMEL-------KHHHTSIVLCTELALLCTQESPQERPTMSDVVHML
    ....  . ....     .. | | | .         . ..      .|.  | .. |..||....... |
PYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR8x_d.AA TK 560-674 14 1.8e-19 61.26 In-house 1-251 (486) Show / Hide 
Range on Protein: 560-674
Range on HMM: 1-251/486
Sequence Identity: 14% (37 aa)

FSSINYIGSSALC---TVYKAELSDGL--------------------------EVAVKVLSPEYYGSNRRSFS----------------MEAKMFAK-VL
   .. .|. . .   .|||.|. ..                           .||||.| ..   | .. |                 .|.||.   ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVKVVG-CCNSVNM-----------VALVSELMPNGS----LEKHLY--AGEVCD-----------------------------------------
 |||||. .| |. ....           . .| |.||.|.    | ..|    ..  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWIQRLDIILGIAEAVAYMH
                               ||  |.| . . ||.. .|.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH
Kinase LRR8x_d.AA MLK 560-674 19 1.3e-17 57.79 In-house 1-141 (291) Show / Hide 
Range on Protein: 560-674
Range on HMM: 1-141/291
Sequence Identity: 19% (28 aa)

FSSINYIGSSALCTVYKAELSDGL----EVAVKVLSPEY-----YGSNRRSFSMEAKMFAKVLHPN----IVKVVGCCNSV-NMVALVSELMPNGSLEKH
.    .|||.. . |.|..    .    .||||    .       .. .. | ||.. .... |||    |....|.|..  . ...|.| ...|||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYAGEV------------CDLTWIQRLDIILGIAEAVAYMH
|....                .  . ... | .|....| |
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLH
Kinase LRR8x_d.AA TKL-Unique 562-693 27 8.4e-17 55.92 In-house 1-146 (290) Show / Hide 
Range on Protein: 562-693
Range on HMM: 1-146/290
Sequence Identity: 27% (40 aa)

SINYIGSSALCTVYKAELSDGLEVAVKVLSP--EYYGSNRRSFSMEAKMFAKVL-HPNIVKVVGCCN----SVNMVALVSELMPNGSLEKHLYA------
 .| ||... ..|||..   | .||.|...|  .   . .. |..| .   |   |||||. .| |     . .   .|.| .| ||| ..|        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--GEVCDLTWIQRLDIILGIAEAVAYMHHEWESLLWCDFRTRSILLD
   . |.|.. ||..... || .  | ||.    . .| .....|.|
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVD
Kinase LRR8x_d.AA Pkinase_Tyr 573-674 28 3e-16 55.67 Pfam 14-128 (270) Show / Hide 
Range on Protein: 573-674
Range on HMM: 14-128/270
Sequence Identity: 28% (34 aa)

TVYKAELS-----DGLEVAVKVLSPEYYGSN---RRSFSMEAKMFAKV-LHPNIVKVVGCCN-----SVNMVALVSELMPNGSLEKHLYAG--EVCDLTW
.|||...      ....||||.| .|.. .    |..|  |||.  .   |||||. .|.|      .   . .| |.||.|.| ..| .   .   || 
EVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQPLTM

IQRLDIILGIAEAVAYMH
 . |.. . ||.. .| .
KDLLQMCWQIAKGMEYLE
Kinase LRR8x_d.AA IRAK 560-674 30 1.9e-15 51.34 In-house 1-126 (317) Show / Hide 
Range on Protein: 560-674
Range on HMM: 1-126/317
Sequence Identity: 30% (39 aa)

FSSINYIGSSALCTVYKAELSDGLE--VAVKVLSPEY---YGSNRRSFSM---EAKMFAKVLHPNIVKVVGCCNSVNMVALVSELMPNGSLEKHLYAGE-
|.  | ||. .  .||.... ....  .||| |  .     .. ...|     | |  ..  ||||| . | |       || ..|||||||  | .   
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDG

VCD---LTWIQRLDIILGIAEAVAYMH
 |    |.|.||..| .|.| .. . |
QCPPKPLSWHQRCSICWGTACGIQFLH
Kinase LRR8x_d.AA TyrKc 560-816 20 1.3e-14 13.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 560-816
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FSSINYIGSSALCTVYKAELSDGLEVAVKVLSPEYYGSNRRSFSMEAKMFAKV--LHPNIVKVVGCCNSV-------NMVALVSELMPNGSLEKHL-YAG
 . .  .|. | ..|||....  ..||||.| ..     |. |  ||..  |.   |||||. .|.| .          . .| |.||.|.| ..| . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

EVCDLTWIQRLDIILGIAEAVAYMHHEWESLLWCDFRTRSILLDALF------------KPHI-------SNYRIAGNPSSEENLP----PAEYMFSSIR
.   |.. . |.. . ||.  .| |.    .   |  .| .|... .              .        . || ..  ..   ||    . | .. .. 
PK--LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TREGDVFSYGVLILEVLTR-ISPQGD-----VSWQGGLALWVQQFYPTTLSDILDPQIMELKHH-------HTSIVLCTELALLCTQESPQERPTMSDVV
| . ||.|.||.. |..|.  .|  .     .|.|              . .. .   |.  ..       . .  . . . . | .| | .|||.|...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ------------EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIH

HML
. .
ECF
Kinase LRR8x_d.AA Pkinase 573-677 18 4e-13 47.5 Pfam 14-128 (293) Show / Hide 
Range on Protein: 573-677
Range on HMM: 14-128/293
Sequence Identity: 18% (22 aa)

TVYKAELSDGLE-VAVKVLSPEYYGS--NRRSFS-MEAKMFAKVLHPNIVKVVGCCNSVNMVALVSELMPNG----SLEKHLY---AGEVCDLTWIQRLD
.|||.   .  . ||||... .   |  ... .  .|... ... |||||.  ... . . . .| |....|    .|  ..     | .  ... .  .
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKF

IILGIAEAVAYMHHEW
... |.....|.| ..
YMYQILRGLEYCHSMG
Kinase LRR8x_d.AA TK-Unique 560-646 27 7.4e-13 40.78 In-house 1-96 (294) Show / Hide 
Range on Protein: 560-646
Range on HMM: 1-96/294
Sequence Identity: 27% (26 aa)

FSSINYIGSSALCTVYKAELSD-------GLEVAVKVLSPEYYGSNRRSFSMEAKMFAKVL-HPNIVKVVGCCNSV-NMVALVSELMPNGSLEKHL
.   ..||. |  .|...|..           |||| |  .  .  .. |  |..|. ..  |||||. .||| .  . . .. | .|.|.|...|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYL
Kinase LRR8x_d.AA UTK 566-674 28 1.7e-10 32.13 In-house 7-135 (296) Show / Hide 
Range on Protein: 566-674
Range on HMM: 7-135/296
Sequence Identity: 28% (37 aa)

IGSSALCTVYKAELSD----GLE--VAVKVLSPEYYGSNRRS----FSMEAK---MFAKVL-HPNIVKVVGCCNSVNMVALVSELMPNGSLEKHLY-AGE
.|. |  .|.||.. .    ..|  |||||....  .   .     | .||.   | ...  |||....|| | .    ..|.|.|.||.| . |  ...
LGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRP

VCD-----LTWIQRLDIILGIAEAVAYMH
 ..     ||  |||.  . ||....|.|
TPPACPHWLTLHQRLCMAWDIARGMQYLH
Kinase LRR8x_d.AA S_TKc 560-819 17 6.3e-10 -31.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 560-819
Range on HMM: 1-231/231
Sequence Identity: 17% (48 aa)

FSSINYIGSSALCTVYKAELSD-GLEVAVKVLSPEYYGSNRRSFSMEAKMFAKVLHPNIVKVVGCCNSVNMVALVSELMPN--GSLEKHLYAGEV--CD-
.  .. ||. |  .|||.   . | .||.|...        ...  | ..  |  ||||||  ... . . . .| |....  |.| ...        . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTWIQRLDIILGIAEAVAYMHHEWESLLWCDFRTRSILLDALFKPHISNYRIAGNPSSEENLPPAEYM----FSSIRTREGDVFSYGVLILEVLTRISP
 ..  .   ..  |..|..|.|      . .|     ||||      |.   .|            .||    . .  ... |. | |... | |..  |
PFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL--TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPP

QGDVSWQGGLALWVQQFYPTTLSDILDPQIMELKHHHTSIVLCTELALLCTQESPQERPTMSDVVH------MLQRI
         ...  ..                      |  ..  .   | |  |..|||  .. .      . . .
FP------QMQMMFKKIG--------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR8x_d.AA STE 560-644 23 1.1e-09 30.51 In-house 1-126 (359) Show / Hide 
Range on Protein: 560-644
Range on HMM: 1-126/359
Sequence Identity: 23% (29 aa)

FSSINYIGSSALCTVYKAELSD----------------GLEVAVKVLSPEYYG----------------SNRRSFSMEAKMFAKVL--HPNIVKVVGCCN
.  |  ||. |  |||||   .                |  .|.|... |                   ... .. .| |.  |    ||||||  ||. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SV-------NMVALVSELMPNGSLEK
         . . .. |.|..|||..
KEGHNHKNDDELWICMEYMDGGSLDD
Kinase LRR8x_d.AA Eph 585-672 34 5e-09 26.31 In-house 34-120 (264) Show / Hide 
Range on Protein: 585-672
Range on HMM: 34-120/264
Sequence Identity: 34% (30 aa)

VAVKVLSPEYYGSNRRSFSMEAKMFAKVLHPNIVKVVGCCNSVNMVALVSELMPNGSLEKHLYAGEVCDLTWIQRLDIILGIAEAVAY
||.| |   |  . |. |  ||       ||||..  |   . . |  | | | |||| . |   .   .|.|| . .. ||| .  |
VAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG-QFTVIQLVGMLRGIASGMKY
Kinase LRR8x_d.AA LISK 565-674 27 9.6e-08 21.03 In-house 1-118 (296) Show / Hide 
Range on Protein: 565-674
Range on HMM: 1-118/296
Sequence Identity: 27% (32 aa)

YIGSSALCTVYKAELS-DGLEVAVKVLSPE----YYGSNRRSFSMEAKMFAKVLHPNIVKVVGCCNS-VNMVALVSELMPNGSLEKHLYAGE--VCDLTW
 ||. .   ||| ..  .| ..|.| ..      .. .... .  | .|  .  |||||. .| |        .| |..  | |.  | . .  . .|.|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

IQRLDIILGIAEAVAYMH
 ||..| |.||.. .| |
PQRVKIALDIACGMSYLH
Kinase LRR8x_d.AA TK 731-816 17 2.7e-07 19.68 In-house 376-486 (486) Show / Hide 
Range on Protein: 731-816
Range on HMM: 376-486/486
Sequence Identity: 17% (22 aa)

DVFSYGVLILEVLT--RISPQGDVSWQGGLALWVQQFYPTTLSDILDPQIMELKHH---------------HTSI--VLCT------------------E
||.|.|||. |..|  .  . |..| |.  .            .  . ..||.                  .     ..|.                  .
DVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD-----------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYD

LALLCTQESPQERPTMSDVVHML
| . | .. |..|||.|.....|
LMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8x_d.AA TK-Unique 798-816 42 1.8e-05 14.94 In-house 276-294 (294) Show / Hide 
Range on Protein: 798-816
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CTQESPQERPTMSDVVHML
|.|..|.|||. ....|.|
CWQWEPEERPSFRQIKHRL
Kinase LRR8x_d.AA UTK 793-816 37 0.002201 7.44 In-house 273-296 (296) Show / Hide 
Range on Protein: 793-816
Range on HMM: 273-296/296
Sequence Identity: 37% (9 aa)

ELALLCTQESPQERPTMSDVVHML
.| . | . .|||||.. |.|  .
RLMHRCWHYDPQERPDFEDLVQQM
Kinase LRR8x_d.AA MLK 731-745 60 0.002218 7.74 In-house 218-232 (291) Show / Hide 
Range on Protein: 731-745
Range on HMM: 218-232/291
Sequence Identity: 60% (9 aa)

DVFSYGVLILEVLTR
||.|.||.. |.|||
DVWSWGVVLWEMLTR
Kinase LRR8x_d.AA LISK 731-748 44 0.002902 6.23 In-house 221-238 (296) Show / Hide 
Range on Protein: 731-748
Range on HMM: 221-238/296
Sequence Identity: 44% (8 aa)

DVFSYGVLILEVLTRISP
||||.|.. .|  ||. .
DVFSFGIVLCEIITRVKA
Kinase LRR8x_d.AA Pkinase_Tyr 793-816 33 0.003933 11.23 Pfam 247-270 (270) Show / Hide 
Range on Protein: 793-816
Range on HMM: 247-270/270
Sequence Identity: 33% (8 aa)

ELALLCTQESPQERPTMSDVVHML
.| ..| .. |..|||.|.....|
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR8x_d.AA Eph 793-816 33 0.007315 5.29 In-house 241-264 (264) Show / Hide 
Range on Protein: 793-816
Range on HMM: 241-264/264
Sequence Identity: 33% (8 aa)

ELALLCTQESPQERPTMSDVVHML
.|.| | |  ...||. ...| .|
QLMLDCWQKDRNHRPHFQQIVSIL
Kinase LRR8x_d.AA TK-Unique 729-744 50 0.020011 4.32 In-house 219-234 (294) Show / Hide 
Range on Protein: 729-744
Range on HMM: 219-234/294
Sequence Identity: 50% (8 aa)

EGDVFSYGVLILEVLT
..|| |.|||. |..|
KSDVWSFGVLMWEIFT
Kinase LRR8x_d.AA IRAK 731-744 64 0.043109 3.41 In-house 206-219 (317) Show / Hide 
Range on Protein: 731-744
Range on HMM: 206-219/317
Sequence Identity: 64% (9 aa)

DVFSYGVLILEVLT
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DVYSFGIVLLEVLT
Kinase LRR8x_d.AA MLK 798-816 31 0.095828 1.99 In-house 273-291 (291) Show / Hide 
Range on Protein: 798-816
Range on HMM: 273-291/291
Sequence Identity: 31% (6 aa)

CTQESPQERPTMSDVVHML
| .. | .||... .|  |
CWNQDPHKRPSFRQIVQHL
Kinase LRR8x_d.AA UTK 727-745 42 0.117851 1.44 In-house 218-236 (296) Show / Hide 
Range on Protein: 727-745
Range on HMM: 218-236/296
Sequence Identity: 42% (8 aa)

TREGDVFSYGVLILEVLTR
|.  ||.|.||.  |..|.
TTKSDVWSFGVVCWEIWTW
Kinase LRR8x_d.AA TKL-Unique 803-816 35 0.123431 1.76 In-house 277-290 (290) Show / Hide 
Range on Protein: 803-816
Range on HMM: 277-290/290
Sequence Identity: 35% (5 aa)

PQERPTMSDVVHML
|..||. ....| |
PSQRPSFDEIIHRL
Kinase LRR8x_d.AA LISK 793-816 29 0.141159 0.66 In-house 273-296 (296) Show / Hide 
Range on Protein: 793-816
Range on HMM: 273-296/296
Sequence Identity: 29% (7 aa)

ELALLCTQESPQERPTMSDVVHML
.|.. |.   | .||. ...|. |
DLCFDCCKYDPKNRPSFKEIVQWL
Kinase LRR8x_d.AA Pkinase 727-748 27 1.517253 3.01 Pfam 190-211 (293) Show / Hide 
Range on Protein: 727-748
Range on HMM: 190-211/293
Sequence Identity: 27% (6 aa)

TREGDVFSYGVLILEVLTRISP
... |..|.|... |.|..  |
GPKVDMWSCGCILYEMLCGRPP
Kinase LRR8x_d.AA Pkinase_Tyr 731-745 53 5.598291 0.55 Pfam 196-210 (270) Show / Hide 
Range on Protein: 731-745
Range on HMM: 196-210/270
Sequence Identity: 53% (8 aa)

DVFSYGVLILEVLTR
|| |.|||. |..|.
DVWSFGVLMWEIFTY