LRRI_a-2

Species: S.moellendorffii
Alias: LRRI_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRRIa

Sequence

Name Sequence Type Origin Length Description Download
LRRI_a-2.AA Protein None 886 None Fasta, JSON
LRRI_a-2.NA RNA None 2658 None Fasta, JSON
LRRI_a-2.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of LRRI_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRRI_a-2.AA LRR_1 420-442 29 1.050526 6.67 Pfam 1-26 (26) Show / Hide
Range on Protein: 420-442
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RIIELNLSS-S--GLKGTISLS-ITKL
.. .|.||.     | |.|. | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRRI_a-2.AA LRR_1 444-465 33 0.002008 16.31 Pfam 1-26 (26) Show / Hide
Range on Protein: 444-465
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HLTKIYLDN-N--ALTGRVPD--FSSL
.|....|.. |   ||| .|.  | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

Kinase LRRI_a-2.AA TKL 598-863 22 2.6e-64 219.98 In-house 1-364 (364) Show / Hide
Range on Protein: 598-863
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

IGEGSFGPVYYGCLPN---------GVEVAVKVLSSNSKQGY---------------------------QEFQTEIDILSVVHHKNLVPFLGYCTQKSK-
||.|.|| || | . .         | .||||...|.. .                             ...  || ..|  .| |.|.|.|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LILVYEFLSNGTLREHLYGEGKRYPTLSWKTRLGIALDAAQGLEYLHT----SCNLH--IIHRDVKTSNILLSFDMV-----------
            | .|.|. ..|.|...|           |  |. .|||.|.|..|||.    .|     ||||| |..|||.  ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKLSDFGLSKFYD---SNKASHVSTG--------------IKGTPGYLDPEYHSYS----------------RLTEKSDVYSFGVVLFEIVCGREPL
   .|..|||||.| .   .....  ...              . |||... ||    .                  .||.||||||.||.||.....  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-P

NFTLLEEQIVLS---EWACKELEKGNLRTVIDPSLS-----DYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
 . . .......   |.  .   . .||  |.|  .        ...   . . . .| .  |. ||...... .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LRRI_a-2.AA IRAK 592-792 34 4.6e-59 202.53 In-house 1-221 (317) Show / Hide
Range on Protein: 592-792
Range on HMM: 1-221/317
Sequence Identity: 34% (77 aa)

SNFKRVIGEGSFGPVYYGCLPNGV-EVAVK----VLSSNSKQGYQEFQT---EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKR
..  ..|||| || || | . |    .|||    . ... ..  |.||.   |. ...  .|.|.||..||||. ... |||....||.|.  | . .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

YP--TLSWKTRLGIALDAAQGLEYLHTSC-NLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFY--DSNKASHVS-----TGIKGTPGYLDPEYHS--YSR
 |   ||| .|. |.. .| |...||.      |||.|.|..||||  ....|..||||  |    |.| ....       ..||  |. ||.      .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKSDVYSFGVVLFEIVCGR
|| |.||||||.|| |.. |.
LTKKTDVYSFGIVLLEVLTGC

Kinase LRRI_a-2.AA TKL-Unique 594-789 32 1.6e-48 167.54 In-house 1-222 (290) Show / Hide
Range on Protein: 594-789
Range on HMM: 1-222/290
Sequence Identity: 32% (73 aa)

FKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQG---YQEFQTEIDILSVVH-HKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLY------G
|  .||||..|.|| |   .| .||.|... |...     |||  |. .... | |.|.| . |||.    . .....| |... |.|...|        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

EGKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFD-----MVAKLSDFGLSKFYDSNKASHVS-------TGIKGTPGYLDPEYH
  ..  .|... |. .|.|.|||..|||..    ||||| |.||.|.. .     . .|..||||||| ... .. ..       .. .|.. .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SY--SRLTEKSDVYSFGVVLFEIV
.   .  .|||||||||.|| ||.
RMNFCQYSEKSDVYSFGIVLWEIA

Kinase LRRI_a-2.AA Dicty4 593-794 36 4.9e-48 158.38 In-house 2-216 (277) Show / Hide
Range on Protein: 593-794
Range on HMM: 2-216/277
Sequence Identity: 36% (79 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVL-SSNSK---QGYQEFQTEIDILSVVHHKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLYG---EG
|.   ||.|||| || |    | |||||.| . | .      .||  |..|..   | |.. |.|.||    ...|.  | |... |.| . |     | 
NIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

KRYPTLSWKTRLG---IALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHV-STGIKGTPGYLDPEYHSYSRLTEKSD
.   .|.| ...    .|.|||.|. .|| .||  ||||| |..|.| . ....| .|||||.     .      .. .|||..  ||     . .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGVVLFEIVCGREP
||||| ||.||. . ||
VYSFGIVLWEILTRQEP

Kinase LRRI_a-2.AA TK 592-794 17 1.7e-47 156.8 In-house 1-394 (486) Show / Hide
Range on Protein: 592-794
Range on HMM: 1-394/486
Sequence Identity: 17% (71 aa)

SNFKRVIGEGSFG---PVYYGCLPNG--------------------------VEVAVKVLSSNSKQGYQEFQT-----------------EIDILS--VV
  . ...||| ||    || | . ..                          ..||||.| . . .  .||.                  |. ...  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNLVPFLGYCTQKSK------------LILVYEFLSNGT----LREHLYGEGKRYPT-----------------------------------------
||.|.| ..|.|||.              ...| |. ..|     ||..|    ..  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWKTRLGIALDAAQGLEYLHTSCNL----HIIHRDVKTSNILLSFDMV-----------AKLSDFGLS
                               |. ...| .....|.|.|||| |.|     ...|||. . |.|.. ..|           .|..|||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH-SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------FYDSNKASHVSTGIKGTPG-------------------------YLDPEYHS---------YSRLTEKSDVYSFGVVLFEIVC-GREP
.        .. ..   .... .||..                         .. ||            | . |.||||.||||...||.  |.||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

Kinase LRRI_a-2.AA Pkinase 592-794 30 1.9e-44 158.22 Pfam 1-211 (293) Show / Hide
Range on Protein: 592-794
Range on HMM: 1-211/293
Sequence Identity: 30% (66 aa)

SNFKRVIGEGSFGPVYYGCLPNGVE-VAVKVLSSNSKQGYQEFQT-----EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNG----TLREHLYGEG
  ..|.||.|||| || ..  .  . ||||...   ..  .. ||     || |.  ..|.| | ...... |... .| |.. .|     | ... .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

KRYPTL--SWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVA----KLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHS-YSRLTE
.|. ..  |...   ...  ..||||.|      |||||.| .|||.. ...     |..||||.|..| .  ..  |.. |||.|. || .  ..  . 
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVYSFGVVLFEIVCGREP
|.|..|.|..|.| .||| |
KVDMWSCGCILYEMLCGRPP

Kinase LRRI_a-2.AA Pkinase_Tyr 593-794 31 9e-44 148.87 Pfam 2-214 (270) Show / Hide
Range on Protein: 593-794
Range on HMM: 2-214/270
Sequence Identity: 31% (70 aa)

NFKRVIGEGSFGPVYYGCLP-----NGVEVAVKVLSSNSKQGY---QEFQTEIDILSVV-HHKNLVPFLGYCT-QKSK--LILVYEFLSNGTLREHLYGE
 | ...|||.|| || | .      ....||||.|  .. .     ..|  |. |..   ||.|.| ..| || |.    ...| |.  .| |...|   
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--GKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASH-VSTG-----IKGTPGYLDPEYHSYSRL
  .|. .|...   |..... |.|.|||.      .||||. . |.|.. ..|.| .||||..    |.    ...|     || ..    ||  .|.. 
REDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMA----PECINYGKF

TEKSDVYSFGVVLFEIVC-GREP
|.||||.||||...||.  |..|
TTKSDVWSFGVLMWEIFTYGEQP

Kinase LRRI_a-2.AA TyrKc 592-863 25 9.2e-44 152.63 SMART 1-280 (280) Show / Hide
Range on Protein: 592-863
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

SNFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQGYQEFQTEIDILSVV--HHKNLVPFLGYCTQK-------SKLILVYEFLSNGTLREHLYGEGK
  .....||| || || | .   ..||||.| ...    ..|  |. |.. .  ||.|.| ..|.|||.         | .| |. ..| |...|   ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSN------KASHVSTGIKGTPG-----YLDPEYHSYSR
.   |..|. | .....|.| ||||     ..||||  . |.|.. . ..| ||||||.. ..       |   .... ||. .      . ||   |..
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKSDVYSFGVVLFEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDP-----SLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
 |.||||.||||...||    ..      ..  .  . . . ...|. .   .      .       .  .. .. ..| .. |. ||..|... ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LRRI_a-2.AA Dicty5 593-794 33 1.1e-38 130.77 In-house 2-202 (260) Show / Hide
Range on Protein: 593-794
Range on HMM: 2-202/260
Sequence Identity: 33% (69 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNS--KQGYQEFQTEIDILSVVH--HKNLVPFLGYCTQKSKL-ILVYEFLSNGTLREHLYGEGK-RYPT
 |  .|  |. | || |   .|  ||.||.|.        .||. |. |.|..   | |.. ..|  ..  |    | |. .||.|.. |    |     
SFHDWIASGASGRVYNGIY-KGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTEKSDVYSFGVVLF
... ..| .|.|.||....|| | |  |||||.|  |.|.  .  .|. ||| | | |  .  |  . . ||. .  .|       ..| ||||||.||.
IAYFQQLHMAIDIAQSMRHLH-SMN--IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRY--HMTMHV-GTQCWMACELFNGQPYHQKCDVYSFGIVLW

EIVCGREP
|.    ||
EMFTRKEP

Kinase LRRI_a-2.AA Ciliate-E2 592-792 21 1.3e-38 130.18 In-house 1-293 (365) Show / Hide
Range on Protein: 592-792
Range on HMM: 1-293/365
Sequence Identity: 21% (63 aa)

SNFKRVIGEGSFGPVYYGCL---PN------------------GVEVAVKVLSSNSKQGYQEFQTEIDILSVVH----------------HKNLVPFLGY
 .| ..||.|.|| ||...    ..                  .| .  . . ...|.. ...  ||.|.  ..                |.|.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CT--QKSKLILVYEFLSNGTLREHLY---GEGKRYPT----LSWKTRLGIALDAAQ---------------GLEYLHTSCNLHIIHRDVKTSNILLSFDM
    ..... || |... |.|.....      .  ..    ...| .. |    .|               .|||||   |  ||||| | .|||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF----

VAKLSDFGLSKFYDSN----------------KASHVSTGIK-------------GTPGYLDPEYHSYSR---------LTEKSDVYSFGVVLFEIVCGR
  |..||||||.|| .                   ....|.              |||||. || ...            ..|.|..|.||.|.| ..|.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK





Kinase LRRI_a-2.AA MLK 592-794 27 2.3e-38 130.72 In-house 1-235 (291) Show / Hide
Range on Protein: 592-794
Range on HMM: 1-235/291
Sequence Identity: 27% (67 aa)

SNFKRVIGEGSFGPVYYGCLPNGV----EVAVKVLSSNSKQGYQE-------FQTEIDILSVVHHKN----LVPFLGYCTQK-SKLILVYEFLSNGTLRE
 .|...||.|||| |. |   |      .||||   ..     ..       |..|. .|... |.|     ..|.| |.|  ... .| |....| | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYG-EGKRYP---------TLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSF------DMVAKLSDFGLSK-FYDS--NKASHVSTGIK
 |.| ..| ..         . .    . .||. |.|..|||      ||||| | .|||..       ....| .|||.|. ....  |.     .. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNM-----MSNA

GTPGYLDPEY---HSYSRLTEKSDVYSFGVVLFEIVCGREP
||. .  ||       .. .||.||.|.|||| |.. ...|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase LRRI_a-2.AA S_TKc 592-867 23 5.1e-38 133.54 SMART 1-231 (231) Show / Hide
Range on Protein: 592-867
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

SNFKRVIGEGSFGPVYYGCLPN-GVEVAVKVLSSNSKQGYQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSN--GTLREHLYGEGKRYPT--
  . |.||.|.|| || .   . | .||.|...       . .. ||.||.  ||.|.| .....   ..| .| |....  |.|....   |.. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTE-KSDVYSFGVVL
..  .   ..   ...|||.|   ...|||||.| .||||.   . |..||||....         | . ||| |. ||       .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDPSLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVI-----QLREAI
.| .||. |       .. .. .  .                          ...  ||| .. | .||    .        . . .
YEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRRI_a-2.AA LRRK 592-794 26 1.8e-37 130.14 In-house 1-282 (351) Show / Hide
Range on Protein: 592-794
Range on HMM: 1-282/351
Sequence Identity: 26% (78 aa)

SNFKRVIGEGSFG-PVYYGCLPN---------------------------GVEVAVKVLSS----------NSKQ------------------------G
  . . ||.|.|| .|| . . .                           . .||.|..            ||                           
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKRY-----PTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNI
..||. |. |.|  .| |.|. .|.| .   |..| |....|.| ..|  . .       . .|| ..| |||. | |.|||| |.|  ||||| |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL-SF-----------DMVAKLSDFGLSK--FYDSNK-ASHVSTGIKGTPGYLDPEYHSY---SRLTEKSDVYSFGVVLFEIVCGR-EP
|| |.           ...||..|||.|   ... .. |.    |  |.||.. ||   |   .  |||.|.||||..|.|.. ..  |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAK----GCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase LRRI_a-2.AA TK-Unique 592-790 27 1.3e-36 123.85 In-house 1-234 (294) Show / Hide
Range on Protein: 592-790
Range on HMM: 1-234/294
Sequence Identity: 27% (66 aa)

SNFKRVIGEGSFGPVYYGCLPN-------GVEVAVKVLS-SNSKQGYQEFQTEIDILSVVH-HKNLVPFLGYCTQKS-KLILVYEFLSNGTLREHLYGEG
.....|||||.||.|. | . .        . |||| |  .....  |.|  || ... .  |.|.| .||.|| ..    ...|....|.|. .|   .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------KRYPT---LSWKTRLGIALDAAQGLEYLHT-SCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSK-FYDSNKASHVSTGIKG
                   ...|    .| |. . .| . |.|.|||.   ..   .|||. ..|.||. | |.|..|||...  |. |..   ... . 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI--VHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGR

TPG-YLDPEYHS--YSRL-TEKSDVYSFGVVLFEIVC
.|  .. ||. .  .    |.||||.||||...||..
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase LRRI_a-2.AA TK 832-863 21 0.001092 7.39 In-house 454-486 (486) Show / Hide
Range on Protein: 832-863
Range on HMM: 454-486/486
Sequence Identity: 21% (7 aa)

ENAALKVL-EVARKCVERSPHRRPNMSTVVIQL
.... ... .. ..| .. | .||..|... ||
PHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRRI_a-2.AA MLK 844-863 35 0.001984 7.91 In-house 272-291 (291) Show / Hide
Range on Protein: 844-863
Range on HMM: 272-291/291
Sequence Identity: 35% (7 aa)

KCVERSPHRRPNMSTVVIQL
.| .  ||.||... .| .|
QCWNQDPHKRPSFRQIVQHL

Kinase LRRI_a-2.AA IRAK 823-863 26 0.012579 5.33 In-house 277-317 (317) Show / Hide
Range on Protein: 823-863
Range on HMM: 277-317/317
Sequence Identity: 26% (11 aa)

IDPSLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
||.  .. ..| ... . .|  |...   ||. |  |. ||
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL

Kinase LRRI_a-2.AA TK-Unique 845-863 26 0.160449 1.16 In-house 276-294 (294) Show / Hide
Range on Protein: 845-863
Range on HMM: 276-294/294
Sequence Identity: 26% (5 aa)

CVERSPHRRPNMSTVVIQL
|  ..|. ||. .... .|
CWQWEPEERPSFRQIKHRL

Kinase LRRI_a-2.AA Pkinase_Tyr 843-863 33 2.817645 1.56 Pfam 250-270 (270) Show / Hide
Range on Protein: 843-863
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

RKCVERSPHRRPNMSTVVIQL
..| .  | .|| .| .. ||
KQCWHYDPEDRPTFSEIHEQL