Gene PERK_d (S.moellendorffii)

PERK_d

Species: S.moellendorffii
Alias: PERK_d
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: PERK

Sequence

Name Sequence Type Origin Length Description Download
PERK_d.AA Protein None 501 None Fasta, JSON
PERK_d.NA RNA None 1506 None Fasta, JSON
PERK_d.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of PERK_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PERK_d.AA IRAK 125-397 33 6.8e-85 288.34 In-house 1-317 (317) Show / Hide 
Range on Protein: 125-397
Range on HMM: 1-317/317
Sequence Identity: 33% (108 aa)

FSRANLLGEGGFGCVYKGFLHGGQ-VVAVKQLRDGSR----QGEREFRA---EVEIISRVHHRHLVSLVGYCIEDAQRLLVYDFVPNGTLEHHLHGEGRT
|...|..|||||||||.| ...   ..||| |. .      . ...|..   |... .| .| ..|.| |||.|  .  |||.. |||.||  |.. . .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

VM----DWPTRLKIASGSARGLAYLHEDCHPR--IIHRDIKSSNILLDNNFDAQVSDFGLAKLA----SDTYTHV----TTRVMGTFGYLAPEYAS--TG
..     |..|..|..|.|.|. .||.. ||   |||.||||.||||| .| .  .||||.       .  .. .    | .| ||  |..||.    .|
CPPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

KLTEKSDVYSFGVVLLELITGRRPVDTT--QPVGKDSLVE------------------------WARPYLMQAIENGDLGGVVDERLANYNENEMLRMVE
.|| |.||||||.||||..||.|.|..    . ... |.|                        || |  || .|       .|.| .  ..|. . |  
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEK-----FIDHRMPPCPPNMEKEMCQ

AAAACVRHSARERPRMAEVVPAL
.|  |. | |..|. ||.|.  |
CACCCGHHRANRRCDMAWVMQQL
Kinase PERK_d.AA TKL 131-397 22 2.2e-70 240.16 In-house 1-364 (364) Show / Hide 
Range on Protein: 131-397
Range on HMM: 1-364/364
Sequence Identity: 22% (88 aa)

LGEGGFGCVYKGFLHG---------GQVVAVKQLRDGSRQGE---------------------------REFRAEVEIISRVHHRHLVSLVGYCIEDAQ-
.|.||||.|||| ..|         |..||||...  . . .                            ... |. ..|| .| ..|...|||..  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYDFVPNGTLEHHLHGEGRTVMDWPTRLKIASGSARGLAYLHEDCH-----PRIIHRDIKSSNILLDNNFD--------------
              .|....|.|.|.|.||        |. |...| . |||..||| .       | |||||.||.|||.|.|.               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AQVSDFGLAKLA----SDTYTHVTTR--------------VMGTFGYLAPEYAS----------------TGKLTEKSDVYSFGVVLLELITGRRPVDTT
. ..||||..      ... |  |..              . ||....|||                    .. .||.||||||.|| |..|..|     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

QPVGKDSLVEWARPYLMQAIEN--------GDLGGVVDERLA-------------NYNENEMLRMVEAAAACVRHSARERPRMAEVVPAL
             ||  .  .          .. .|.|..|                ... . .| . .  |  | ...|| . |..  |
-------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase PERK_d.AA TKL-Unique 127-324 34 2e-50 173.81 In-house 1-233 (290) Show / Hide 
Range on Protein: 127-324
Range on HMM: 1-233/290
Sequence Identity: 34% (80 aa)

RANLLGEGGFGCVYKGFLHGGQVVAVKQLR---DGSRQGEREFRAEVEIISRVH-HRHLVSLVGYCI----EDAQRLLVYDFVPNGTLEHHLHG------
  |..||||.| ||||  . |  ||.||.    | | . ..||. || .... | |  .| ..|||.      ... .| ...| |.|  .||       
FWNKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--EGRTVMDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNN-----FDAQVSDFGLAKLAS-DTYTHVT-------TRVMGTFGYLAPEYA
  .  . ...  |.|.|   |.|. |||    | |||||.||||.|.|||     . ....||||.|..| .. . ..       . ..|.| ..|||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

ST--GKLTEKSDVYSFGVVLLELITGRR------P
.    . .|||||||||.|| |..|. .      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase PERK_d.AA LRRK 125-326 29 2.6e-49 170.16 In-house 1-284 (351) Show / Hide 
Range on Protein: 125-326
Range on HMM: 1-284/351
Sequence Identity: 29% (84 aa)

FSRANLLGEGGFG-CVYKGFLHG---------------------------GQVVAVKQLRDG---------------------SRQGE------------
. . ...|.||||  ||.. . |                           .| ||.|..  .                     | |.|            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-REFRAEVEIISRVHHRHLVSLVGYCIEDAQRLLVYDFVPNGTLEHHLH---GEGR----TVMDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNI
 |||| || |.|. .| ..|||.|.||.   . .| ...|.|.| |.||     |.    ....| ..||||   |.|..||| ...| ||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL---D---------NNFDAQVSDFGLAKLASDTYTH-VTTRVMGTFGYLAPEYASTG---KLTEKSDVYSFGVVLLELITGR-RPVD
||   .         ..  | ..|||.  .   .... |. .. |..|..|||    .     |||.|.||||..| ||.|.. .| |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase PERK_d.AA TK 125-324 17 2e-45 149.81 In-house 1-394 (486) Show / Hide 
Range on Protein: 125-324
Range on HMM: 1-394/486
Sequence Identity: 17% (70 aa)

FSRANLLGEGGFG---CVYKGFLHGG--------------------------QVVAVKQLRDGSRQGEREFRA--------------EVEIISRVH----
    . |||| ||    |||| ..|.                          . ||||.|..|. . ..||..              |.|...  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRHLVSLVGYCIEDAQ------------RLLVYDFVPNGT----LEHHLH--GEGRTV-----------------------------------------
 | ..|.|.|.| ...              ..|  ..|.|     | ..|.   ....                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------MDWPTRLKIASGSARGLAYLHED----CHPRIIHRDIKSSNILLDNNFD-----------AQVSDFGLA
                               .. ...| ..   |.|..|||.       ....|||.   |.|...|             . ..||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----LASDTYTHVTTRVMGTFG----------------------------YLAPEYAS---------TGKLTEKSDVYSFGVVLLELIT-GRRP
.     || | | .   ..... |                            ..|||            .|| |.||||.||||.. |. | |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase PERK_d.AA Pkinase_Tyr 125-324 30 6.2e-44 149.42 Pfam 1-214 (270) Show / Hide 
Range on Protein: 125-324
Range on HMM: 1-214/270
Sequence Identity: 30% (67 aa)

FSRANLLGEGGFGCVYKGFLH-----GGQVVAVKQLRDGSRQGE---REFRAEVEIISRV-HHRHLVSLVGYCI-EDAQ--RLLVYDFVPNGTLEHHLHG
 .    |||| || |||| ..     ... |||| |..|. . .   ..| .|..| .   || ..|.|.| |. .. .   ..|  ..|.| | ..|. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E--GRTVMDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAKLA-SDTYT-HVTTRVMGTFGYLAPEYASTGKLTEKSDV
   ..   . .. |...   |.|..||..     .||||.   |.|...|. . ..|||||..  .| |  ....  .     .|||  ..|| |.||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSFGVVLLELIT-GRRP
.||||.. |..| |. |
WSFGVLMWEIFTYGEQP
Kinase PERK_d.AA Dicty4 125-324 33 5.7e-43 141.26 In-house 1-216 (277) Show / Hide 
Range on Protein: 125-324
Range on HMM: 1-216/277
Sequence Identity: 33% (74 aa)

FSRANLLGEGGFGCVYKGFLHGGQVVAVKQL---RDGSRQGE-REFRAEVEIISRVHHRHLVSLVGYCI----EDAQRLLVYDFVPNGTLEHHLHG----
  . ...|.|.|| ||||    |. |||| |    ..... .  |||.||.| .   | ... . |.|.    .    . |  ..| |.|.  ||     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

-EGRTVMDWPTRLK---IASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAK-LASDTYTHV-TTRVMGTFGYLAPEYASTGKLTEKS
   .. .|||....   .|   |||...||. | |.|||||.||.|.| | |. . |.||||..    ..     .. . || .. |||       .||.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVLLELITGRRP
|||||| || |. |.  |
DVYSFGIVLWEILTRQEP
Kinase PERK_d.AA Pkinase 125-322 28 1.5e-42 151.53 Pfam 1-209 (293) Show / Hide 
Range on Protein: 125-322
Range on HMM: 1-209/293
Sequence Identity: 28% (62 aa)

FSRANLLGEGGFGCVYKGFLHGGQV-VAVKQLRDGSRQG--EREFRA--EVEIISRVHHRHLVSLVGYCIEDAQRLLVYDFVPNG----TLEHHLHGEGR
. .   .|.|.||||||.  .| .  ||||...  ..    ... |   |..|  |..| . | | ... ..    .| .....|     | ...... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TVM--DWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDA----QVSDFGLAKLA-SDTYTHVTTRVMGTFGYLAPEYAS-TGKLTEKSD
...  .. .  ...   .|||.|.|.    .|||||.|..|||.||| .      ..||||||..    ..  ||.. || .|.|||      . . |.|
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC-GTPWYMAPEVIRGGQYYGPKVD

VYSFGVVLLELITGR
..|.|..| |...||
MWSCGCILYEMLCGR
Kinase PERK_d.AA MLK 125-324 27 6.4e-42 143.23 In-house 1-235 (291) Show / Hide 
Range on Protein: 125-324
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

FSRANLLGEGGFGCVYKGFLHGGQ----VVAVKQLR----DGSRQG--EREFRAEVEIISRVHHRH----LVSLVGYCIEDAQ-RLLVYDFVPNGTLEHH
.     .|.|.|| |.||  ..      .||||. |    | |. .   ..|. |... ... |.      . ..| |... .  ..|  ....| | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHGEGR------------TVMDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDN------NFDAQVSDFGLAKLASDTYTHVTTRVMGTFGY
|||.               |.|    ...|   |||..|||..  . |||||.||.|||.|.      . .. ..|||...  ...     .  .||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

LAPEY---ASTGKLTEKSDVYSFGVVLLELITGRRP
 |||    .  .| .||.||.|.|||| |..|.. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase PERK_d.AA Dicty4-Unclassified 128-324 32 5.5e-37 124.18 In-house 4-207 (263) Show / Hide 
Range on Protein: 128-324
Range on HMM: 4-207/263
Sequence Identity: 32% (68 aa)

ANLLGEGGFGCVYKGFLHGGQVVAVKQLRDGSRQGE----REFRAEVEIISRVHHRHLVSLVGYCIED----AQRLLVYDFVPNGTLEHHLH---GEGRT
   .|.| |  |.||   |   |||| . ... .       .|..||||   . |  || . ||||      .    |  | . |.|    |    |   
DQFIGKGHFSKVHKGNWKGKD-VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

VMDWPT--RLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAKLASDTYTHVTTRVMGTFGYLAPEYASTGKLTEKSDVYSFGVV
 .       .|.|   |.|...||      .|||||||||||.| .| . . |||..   . ...   | . ||    .||       . ||||||....
PIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN--MTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LLELITGRRP
| ||.||  |
LYELATGDEP
Kinase PERK_d.AA TK-Unique 125-320 24 6.9e-37 124.77 In-house 1-234 (294) Show / Hide 
Range on Protein: 125-320
Range on HMM: 1-234/294
Sequence Identity: 24% (58 aa)

FSRANLLGEGGFGCVYKGFLHG-------GQVVAVKQLRDGSRQGE-REFRAEVEIISRVH-HRHLVSLVGYCIEDA-QRLLVYDFVPNGTLEHHLHGEG
.   ...||| ||.|..| . |        ..||||.|.|.... . ..|  | .. . .  | ..|...|.|...  . .... ..|.|.|.|.|.  .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

RT-----------------VMDWPTR-LK------IASGSARGLAYLHE--DCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAKLASD--TYTHVTTRVM
..                  .. .|  ..      .| . |.|..||..  .   .|.|||. ..|.|| ... . ..|||.|.  ..   |   ... .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRK---KIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

GTFGYLAPEYAS--TGKL-TEKSDVYSFGVVLLELIT
    ..|||. .  .|   |.||||.||||.. |. |
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase PERK_d.AA TyrKc 125-397 25 1.5e-36 128.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 125-397
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FSRANLLGEGGFGCVYKGFLHGGQVVAVKQLRDGSRQGEREFRAEVEIISRV--HHRHLVSLVGYCIED-------AQRLLVYDFVPNGTLEHHLHGEGR
 .    |||| || |||| .   . |||| |....   ...|. | .| ...  || ..| |.|.|...        . ..|  ..|.| | ..|.  ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TVMDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAKLASDT--------YTHV----TTRVMGTFGYLAPEYASTGKLT
.   ... |...   |.| .|||.    ..||||.   |.|...|. . .|||||..   |         | ..     .. |     .|||   .|| |
K-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKSDVYSFGVVLLELIT-GRRPVDT---TQPVGKDSLVEWARPYLMQAIENGDLGGVVDERLANYNENEM------LRMVEAAAACVRHSARERPRMAEV
.||||.||||.. |. | |  |        ..  . ..|. .   .  .   |.              .|        | .    | .. . .||...|.
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY--------------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

VPAL
.  .
HECF
Kinase PERK_d.AA S_TKc 125-397 22 2.5e-36 127.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 125-397
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FSRANLLGEGGFGCVYKGFLHG-GQVVAVKQLRDGSRQGEREFRAEVEIISRVHHRHLVSLVGYCIEDAQRLLVYDFVPN--GTLEHHLHGEGR----TV
.   ...|.|.||.|||.  .. |..||.|...       . .| |..| .. || ..| | ... .     .| .....  |.| ....  ||     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MDWPTRLKIASGSARGLAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFGLAKLASDTYTHVTTRVMGTFGYLAPEYASTGKLTE-KSDVYSFGVVLL
..  .  ...   ...|.|.|.  | .|||||.| .|||||.     ..|||||..         | . ||  |.|||     . .  |.|..|.|..| 
FPE-HARFYMYQICCALEYCHS--H-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELITGRRPVDTTQPVGKDSLVEWARPYLMQAIENGDLGGVVDERLANYNENEMLRMVEAAA----ACVRHSARERPRMAEVV---------PAL
|...|. | .                 ... |                         . |      | .   ..||   |.          | .
EMLCGYPPFP-------------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PERK_d.AA STE 125-324 20 3.1e-33 114.75 In-house 1-267 (359) Show / Hide 
Range on Protein: 125-324
Range on HMM: 1-267/359
Sequence Identity: 20% (57 aa)

FSRANLLGEGGFGCVYKGFLHG----------------GQVVAVKQLR-DGSR----------------QGEREFRAEVEIISRVH--HRHLVSLVGYCI
. .   .|.|.|| |||.  |                 |...|.||.. . ..                . . ..  |..| .. .  | . |   |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EDA-------QRLLVYDFVPNGTLE---HHLHGEGR---------TVMDWPTRLKIASGSARG-LAYLHEDCHPRIIHRDIKSSNILLDNNFDAQVSDFG
 .        .  ..  ....|.|.   .| .| |.         .... .   .|.    .| |.|||.     |||||||..||||     .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAKLASD---------------TYTHVTTRVMGTFGYLAPEYAST------GKLTEKSDVYSFGVVLLELITGRRP
...  .|               |    .. . ||  . |||  .       .. ..|.|..|.| ...|..||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase PERK_d.AA TK 360-397 12 0.01128 3.93 In-house 450-486 (486) Show / Hide 
Range on Protein: 360-397
Range on HMM: 450-486/486
Sequence Identity: 12% (5 aa)

RLANYNENEMLRMVEA-AAACVRHSARERPRMAEVVPAL
|     ....  ...     | .. ...||...... .|
RM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase PERK_d.AA MLK 384-397 28 0.158671 1.22 In-house 278-291 (291) Show / Hide 
Range on Protein: 384-397
Range on HMM: 278-291/291
Sequence Identity: 28% (4 aa)

ARERPRMAEVVPAL
...|| ....|. |
PHKRPSFRQIVQHL