Gene RLCK-OS3_c-2 (S.moellendorffii)

RLCK-OS3_c-2

Species: S.moellendorffii
Alias: RLCK-OS3_c-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK-OS3

Sequence

Name Sequence Type Origin Length Description Download
RLCK-OS3_c-2.AA Protein None 354 None Fasta, JSON
RLCK-OS3_c-2.NA RNA None 1065 None Fasta, JSON
RLCK-OS3_c-2.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of RLCK-OS3_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK-OS3_c-2.AA TKL 20-297 18 2.6e-59 203.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-297
Range on HMM: 1-364/364
Sequence Identity: 18% (75 aa)

LGSGSAGLVHKGVLPS---------GQLVAIKHIDK-----------------------------EKKADTFFQEVESLSKVRHPNLVSLLGYCQSFEG-
.|||. | |.||..           |. ||.| . .                             ..  ... .|. ..|. ||||.|...|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YYLVYEFCANGNLWQWLFGDRPPLTWEERLNIAVGSARGLFFLHTNVG-----GAIIHRDVKPTNILLNDNME--------------A
            ...|.|.| .|.|.  |        |. |...| . |||. .||..        .||||| |. |||...|..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLSDFGLSKFITMEESHVFTE------------------VKGTSGYLDPEYMS----------------RGQLTLASDIYSFGIVLLQLVSGRRSIDFAL
|..|||||.|......   |.                  . || ... || .                  .. . ..|.|||||||  .....|      
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR------

QHRYSLVRAVSGNHFTQSSLPFL-LFQAQRV------AERGSDIHKFADPLMDRKFS--------AAAALKIVEIAVFCTAQSSYDRPTIKEINETL
                    |.  .   ...      ..   ...|.  |...   .          .   . ...  | ..   .||. .|| ..|
--------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RLCK-OS3_c-2.AA IRAK 14-212 34 3.4e-54 186.37 In-house 1-225 (317) Show / Hide 
Range on Protein: 14-212
Range on HMM: 1-225/317
Sequence Identity: 34% (78 aa)

FSSENYLGSGSAGLVHKGVLPSGQ-LVAIK------HIDKEKKADTFFQ---EVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANGNLWQWLFGDR--
|. .| .|.|  | | .|..      .|.|       .  ...   | |   |...... ||||.|.|.|||   . . |||.. .|| |   | .    
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-PP--LTWEERLNIAVGSARGLFFLHTNV-GGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFI----TMEESHV----FTEVKGTSGYLDPEYMS--RGQ
 ||  |.|  |. |. |.|.|. |||.|  . .|||.|.|. |||| .....|..||||  |      .| . .       |.||  |. ||..    ||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTLASDIYSFGIVLLQLVSGRRSID
||  .|.|||||||| ...|.|  .
LTKKTDVYSFGIVLLEVLTGCRAVY
Kinase RLCK-OS3_c-2.AA Pkinase 14-208 27 8.4e-42 148.89 Pfam 1-209 (293) Show / Hide 
Range on Protein: 14-208
Range on HMM: 1-209/293
Sequence Identity: 27% (59 aa)

FSSENYLGSGSAGLVHKGVLPSGQL-VAIKHIDKEKKADTFFQ------EVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANG----NLWQWLF-GDR
.  .  .|||| | | |..  . .  ||.| |.|... . . |      |.. . ...||| | |......   .|.| |.| .|     |. ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PPL--TWEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEA----KLSDFGLSKFITMEESHVFTEVKGTSGYLDPEYMS-RGQLTLASDI
 ..  ...|  ...   .||| ..| .    |||||.|| |||...|..     |..||||.|..    .. .| . ||..|. ||    .   . ..|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGIVLLQLVSGR
.|.|..| ....||
WSCGCILYEMLCGR
Kinase RLCK-OS3_c-2.AA MLK 14-208 24 8.7e-34 114.63 In-house 1-233 (291) Show / Hide 
Range on Protein: 14-208
Range on HMM: 1-233/291
Sequence Identity: 24% (57 aa)

FSSENYLGSGSAGLVHKGVLPSGQL-----VAIKHID--------KEKKADTFFQEVESLSKVRHPN----LVSLLGYCQSFEG-YYLVYEFCANGNLWQ
.  . ..|||| | |.||.   ...     ||.| ..        ..  .. | .|.. |....|||     . ..| |.. .  ...| |.|..| |  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFGDRP-------------PLTWEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLND------NMEAKLSDFGLSKFITMEESHVFTEVKGTSG
 | | |.               . .  .|.|.  |||. .|| .   .||||| |. |||. .      .. .| .|||.|....  .    .  .||  
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLDPEYM---SRGQLTLASDIYSFGIVLLQLVSGR
.  ||       .. . ..|..|.|.|| ......
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase RLCK-OS3_c-2.AA TKL-Unique 18-201 30 3.7e-33 114.36 In-house 3-218 (290) Show / Hide 
Range on Protein: 18-201
Range on HMM: 3-218/290
Sequence Identity: 30% (67 aa)

NYLGSGSAGLVHKGVLPSGQLVAIKHIDK-EKKA----DTFFQEVESLSKVR-HPNLVSLLGYCQ----SFEGYYLVYEFCANGNLWQWLF---------
| .|.|..| | ||. . |  |||| . . |..     ..|  ||  ..| . |||.| . |||     .   ...| |.|  |.|   |          
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

GDRPPLTWEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLNDN-----MEAKLSDFGLSKFITMEESHVFT--------EVKGTSGYLDPEYMSR
 .  .|... |...|   |.|. .||.. .  ||||| |..|.|.. |     . .|..||||||| . .    ..        ...|.  .. || ...
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GQLTLASDIYSFGIVL
   | .  ||.|||||||
NFCQYSEKSDVYSFGIVL
Kinase RLCK-OS3_c-2.AA Ciliate-E2 14-209 19 8.4e-32 106.44 In-house 1-294 (365) Show / Hide 
Range on Protein: 14-209
Range on HMM: 1-294/365
Sequence Identity: 19% (60 aa)

FSSENYLGSGSAGLVHKGVL------------------------PSGQLVAIKHIDK-----EKKADTFFQEVE----------SLSKVRHPNLVSLLGY
.   . .|.|. | | |.                            ....|.| . |      |. .  ..|..           |... |||.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CQ--SFEGYYLVYEFCANGNLWQ-----WLFG------DRPPLTWEERLNIAVGSAR---------------GLFFLHTNVGGAIIHRDVKPTNILLNDN
 |  . . .||| |.|  |.|..     ...       |  ..|..|...|    ..               .| .|| .    ||||| || |||.   
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF---

MEAKLSDFGLSKFITME---ESHVFTEVK----------------------------GTSGYLDPEYMSRGQ---------LTLASDIYSFGIVLLQLVS
   |..||||||... .   ..| . . |                            || ||. ||  ....          . ..||.|.|..| ....
--IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GRR
|..
GKP
Kinase RLCK-OS3_c-2.AA S_TKc 14-278 22 1.8e-30 108.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

FSSENYLGSGSAGLVHKGVLPS-GQLVAIKHIDKEKKADTFFQEVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCAN--GNLWQWLFGDRPP-----LT
.   . .|.|. | |.|..  . |..|||| |.     ... .|.. |.| .|||.| |....|. . .|.| |.| .  |.| . .   ...     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITMEESHVFTEVKGTSGYLDPEYMSRGQLTL-ASDIYSFGIVLLQL
  .   ..   ...| ..| . |  |||||.|| ||||..  . |..||||....        | . ||  |. || .   . .  ..|..|.|..|  .
E-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VSGRRSIDFALQHRYSLVRAVSGNHFTQSSLPFLLFQAQRVAERGSDIHKFADPLMDRK----FSAAAALK----IVEIAVF
..|.   .  .|  . ...                          ..   | . ....      .|  ||.    |     |
LCGYPPFP-QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK-OS3_c-2.AA Dicty4 14-205 31 1.9e-30 98.85 In-house 1-211 (277) Show / Hide 
Range on Protein: 14-205
Range on HMM: 1-211/277
Sequence Identity: 31% (67 aa)

FSSENYLGSGSAGLVHKGVLPSGQLVAIKHI--DKEK-KADT---FFQEVESLSKVRHPNLVSLLGYCQ----SFEGYYLVYEFCANGNLWQWLFG----
   |. .|.|| | |.||    |. ||.|    ....  ...   | .||. ..| ||||.. ..|.|       .    | |..  |||   |      
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--DRPPLTWEERLN---IAVGSARGLFFLHT-NVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITMEESHVF--TEVKGTSGYLDPEYMSRGQLTLA
  .. .| |. ..    .|   |||.  ||. |.   ||||| |. |.|  .|. .| .|||||. .  .|.| .  . ..|| ..  || |     . .
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

SDIYSFGIVLLQLV
.| ||||||| ...
ADVYSFGIVLWEIL
Kinase RLCK-OS3_c-2.AA STE 14-208 20 2.1e-30 104.59 In-house 1-265 (359) Show / Hide 
Range on Protein: 14-208
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FSSENYLGSGSAGLVHKGVLP----------------SGQLVAIKHIDKEK-------------------KADTFFQEVESLSKVR--HPNLVSLLGYCQ
.     .|.|. | |.|..                  .|...||| ...|.                   . . . .|.. ..| .  ||| |  .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SF-------EGYYLVYEFCANGNLWQWLF---GDRPPLTW---------EERL-NIAVGSARG-LFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFG
         .  ... |....| | . .    |   ||.          |. .  |..   .| | .|| .    |||||.|| ||||     .||.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKFITME--------------ESH-VFTEVKGTSGYLDPEYMSR------GQLTLASDIYSFGIVLLQLVSGR
... .| .               .    . . ||  .  || ...      .. .  .||.|.|.... .. |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase RLCK-OS3_c-2.AA TK 14-206 15 2.2e-30 98.47 In-house 1-389 (486) Show / Hide 
Range on Protein: 14-206
Range on HMM: 1-389/486
Sequence Identity: 15% (59 aa)

FSSENYLGSGSAG---LVHKGVLPSG--------------------------QLVAIKHIDKE--KKADTFFQ--------------EVESLSKVR----
   .. ||.|  |    |.|| . ..                          . ||.| . ..    .. ||.              |.| ... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVSLLGYCQSFEG------------YYLVYEFCANGN----LWQWLFGDRPP--------------------------------------------
 |||.|.|.|.|   |.            ...| |....|.    | ..|   ||.                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWEERLNIAVGSARGLFFLHTN--VGG--AIIHRDVKPTNILLNDNME-----------AKLSDFG--
                               || ...| ...  |.|. .|| .    .   ..|||.   |.|...|.            .|..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSKFITMEESHVFTEVKGTSG-------------------------YLDPEYMS---------RGQLTLASDIYSFGIVLLQLVS
      |.. |  ..  . .. .||..                         .. || .           |  | .||..|||...  ...
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase RLCK-OS3_c-2.AA LRRK 14-209 23 9.1e-30 102.48 In-house 1-281 (351) Show / Hide 
Range on Protein: 14-209
Range on HMM: 1-281/351
Sequence Identity: 23% (67 aa)

FSSENYLGSGSAG-LVHKGVLPS---------------------------GQLVAIKHIDKE------------------------------------KK
. .|. .|.|. | .|... . .                           .| |||| ....                                    ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ADTFFQEVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANGNLWQWLF---GDR-----PPLTWEERLNIAVGSARGLFFLHTNVGGA--IIHRDVKPT
  .| .||  .|. .|||.|||.|.|  .. . .| |.  .|.| . |.    |.     . ..|  .| ||.  |.|. .|| .      ||||| |. 
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH---NPPIIHRDLKSP

NILL---N---------DNMEAKLSDFGLSK-FITMEESHVFTEVKGTSGYLDPEYMSRG---QLTLASDIYSFGIVLLQLVSGR-R
||||   .         ... ||..|||.|  | .   . |.  . |. |.. || |  .   . |  .|.||||..|  |.... .
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase RLCK-OS3_c-2.AA Pkinase_Tyr 20-201 28 8.7e-27 91.34 Pfam 7-204 (270) Show / Hide 
Range on Protein: 20-201
Range on HMM: 7-204/270
Sequence Identity: 28% (58 aa)

LGSGSAGLVHKGVLP-----SGQLVAIKHIDKEKKADT------FFQEVESLSKV-RHPNLVSLLGYCQ-SFEG--YYLVYEFCANGNLWQWLFGD---R
||.|. | |.||..       .. ||.| . ||.  .       |..|.. ...  .|||.|.|.| |    |   .|.| |....|.|   |      .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

PPLTWEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITMEESH-VFTE-----VKGTSGYLDPEYMSRGQLTLASDIY
.||| .. |....  |.|. .|. .    .||||.   |.|...|. .| .||||.. |. ..   . ..     .| ..    || .. |  | .||..
QPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMA----PECINYGKFTTKSDVW

SFGIVL
|||...
SFGVLM
Kinase RLCK-OS3_c-2.AA TyrKc 14-297 22 3.1e-17 55.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-297
Range on HMM: 1-280/280
Sequence Identity: 22% (74 aa)

FSSENYLGSGSAGLVHKGVLPSGQLVAIKHIDKEKKADTFFQEVESLSKV--RHPNLVSLLGYCQSF-------EGYYLVYEFCANGNLWQWLFGDRPPL
 . .  ||.|  | |.||..   . ||.| . ...    | .| . ..|.  .|||.| |.|.| .        | ...| |....|.| . |   || |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TWEERLNIAVGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITME-------ESHVFTE---VK--GTSGYLDPEYMSRGQLTLAS
.... |....  |.|  .|| .    .||||    |.|...|  .| ||||||..|. .       .  . .|    |       . || .  |  | .|
CMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIYSFGIVL-----------LQL----VSGRRSIDFALQHRYSLVRAV----SGNHFTQSSLPFLLFQAQRVAERGSDIHKFADPLMDRKFSAAAALKIV
|..|||...                  .| .. | .  | ..    .     |                                     |   .  .. 
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------F-VCCPDEMY

EIAVFCTAQSSYDRPTIKEINETL
.|   | .    |||| .|| | .
QIMKQCWHEDPEDRPTFSEIHECF
Kinase RLCK-OS3_c-2.AA ULK 14-93 26 1e-15 52.31 In-house 1-104 (324) Show / Hide 
Range on Protein: 14-93
Range on HMM: 1-104/324
Sequence Identity: 26% (28 aa)

FSSENYLGSGSAG-LVHKGV-LPS---GQLVAIKHIDKEKKAD------------TFFQEVESLSKVR---HPN--LVSLLGYCQSFEG--YYLVYEFCA
..  . ||.|| |  |.||    .   .|.||.| ||| |  .             . .|.. . |     |||   | |. ....     .|...|.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGNL
 |.|
GGDL
Kinase RLCK-OS3_c-2.AA ULK 131-208 25 5.5e-15 49.68 In-house 147-249 (324) Show / Hide 
Range on Protein: 131-208
Range on HMM: 147-249/324
Sequence Identity: 25% (26 aa)

IIHRDVKPTNILLNDN------------MEAKLSDFGLSKFIT--MEESHVFTEVK------GTSGYLDPE-YMSRG---QLT-LASDIYSFGIVLLQLV
||||| || |||....              .|..|||..|..   ..|  .... .      ||  |  |.  ...|   . .   .||.|.|... ...
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGR
 |.
YGK
Kinase RLCK-OS3_c-2.AA IRAK 269-297 13 0.221283 0.86 In-house 289-317 (317) Show / Hide 
Range on Protein: 269-297
Range on HMM: 289-317/317
Sequence Identity: 13% (4 aa)

ALKIVEIAVFCTAQSSYDRPTIKEINETL
....   |. |...    |.....  ..|
EKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase RLCK-OS3_c-2.AA Pkinase_Tyr 286-297 66 7.447903 0.13 Pfam 259-270 (270) Show / Hide 
Range on Protein: 286-297
Range on HMM: 259-270/270
Sequence Identity: 66% (8 aa)

DRPTIKEINETL
|||| .|| | |
DRPTFSEIHEQL