Gene RLCK-OS3_c-1 (S.moellendorffii)

RLCK-OS3_c-1

Species: S.moellendorffii
Alias: RLCK-OS3_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK-OS3

Sequence

Name Sequence Type Origin Length Description Download
RLCK-OS3_c-1.AA Protein None 352 None Fasta, JSON
RLCK-OS3_c-1.NA RNA None 1059 None Fasta, JSON
RLCK-OS3_c-1.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of RLCK-OS3_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK-OS3_c-1.AA TKL 18-295 18 9e-62 211.54 In-house 1-364 (364) Show / Hide 
Range on Protein: 18-295
Range on HMM: 1-364/364
Sequence Identity: 18% (75 aa)

LGSGSAGLVHKGVLPS---------GQLVAIKHIDK-----------------------------EKKADTFFQEVESLSKVRHPNLVSLLGYCQSFEG-
.|||. | |.||..           |. ||.| . .                             ..  ... .|. ..|. ||||.|...|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YYLVYEFCANGNLWQWLFGDRPPLTWEERLNIALGSARGLFFLHTNVG-----GAIIHRDVKPTNILLNDNME--------------A
            ...|.|.| .|.|.  |        |. |...||. |||. .||..        .||||| |. |||...|..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLSDFGLSKFITMEESHVFTE------------------VKGTSGYLDPEYMS----------------RGQLTLASDIYSFGIVLLQLVSGRKPIDFNL
|..|||||.|......   |.                  . || ... || .                  .. . ..|.|||||||  ......      
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR------

QHRYSLVRAVSGNHFTQSSLPFL-LSQAQRV------AERGSDIHKFADPLMDRKFS--------AAAALKIVEIAVFCTAQSSNDRPTIKEINETL
                    |.  .   ...      ..   ...|.  |...   .          .   . ...  | ..  ..||. .|| ..|
--------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RLCK-OS3_c-1.AA IRAK 12-295 28 7.6e-58 198.5 In-house 1-317 (317) Show / Hide 
Range on Protein: 12-295
Range on HMM: 1-317/317
Sequence Identity: 28% (92 aa)

FSSENYLGSGSAGLVHKGVLPSGQ-LVAIK------HIDKEKKADTFFQ---EVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANGNLWQWLFGDR--
|. .| .|.|  | | .|..      .|.|       .  ...   | |   |...... ||||.|.|.|||   . . |||.. .|| |   | .    
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-PP--LTWEERLNIALGSARGLFFLHTNV-GGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFI----TMEESHV----FTEVKGTSGYLDPEYMS--RGQ
 ||  |.|  |. |..|.|.|. |||.|  . .|||.|.|. |||| .....|..||||  |      .| . .       |.||  |. ||..    ||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTLASDIYSFGIVLLQLVSGRKPIDFNLQHRYSLVRAVSGNHFTQSSLPFLLS--------QAQRVAERGSDIHKFADPLMDRKFSAAAALKIVEIAVFC
||  .|.|||||||| ...|... . .  . | |.  .. .    ..|   .|         |     |  .. || |..|      . ....   |. |
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRM-PPCPPNMEKEMCQCACCC

TAQSSNDRPTIKEINETL
...  | |.....  ..|
GHHRANRRCDMAWVMQQL
Kinase RLCK-OS3_c-1.AA Pkinase 12-206 27 1.8e-42 151.28 Pfam 1-209 (293) Show / Hide 
Range on Protein: 12-206
Range on HMM: 1-209/293
Sequence Identity: 27% (59 aa)

FSSENYLGSGSAGLVHKGVLPSGQL-VAIKHIDKEKKADTFFQ------EVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANG----NLWQWLF-GDR
.  .  .|||| | | |..  . .  ||.| |.|... . . |      |.. . ...||| | |......   .|.| |.| .|     |. ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PPL--TWEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEA----KLSDFGLSKFITMEESHVFTEVKGTSGYLDPEYMS-RGQLTLASDI
 ..  ...|  ....  .||| ..| .    |||||.|| |||...|..     |..||||.|..    .. .| . ||..|. ||    .   . ..|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGIVLLQLVSGR
.|.|..| ....||
WSCGCILYEMLCGR
Kinase RLCK-OS3_c-1.AA MLK 12-208 24 3.9e-35 119.39 In-house 1-235 (291) Show / Hide 
Range on Protein: 12-208
Range on HMM: 1-235/291
Sequence Identity: 24% (59 aa)

FSSENYLGSGSAGLVHKGVLPSGQL-----VAIKHID--------KEKKADTFFQEVESLSKVRHPN----LVSLLGYCQSFEG-YYLVYEFCANGNLWQ
.  . ..|||| | |.||.   ...     ||.| ..        ..  .. | .|.. |....|||     . ..| |.. .  ...| |.|..| |  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFGDRP-------------PLTWEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLND------NMEAKLSDFGLSKFITMEESHVFTEVKGTSG
 | | |.               . .  .|.||  |||. .|| .   .||||| |. |||. .      .. .| .|||.|....  .    .  .||  
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLDPEYM---SRGQLTLASDIYSFGIVLLQLVSGRKP
.  ||       .. . ..|..|.|.|| ...... |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase RLCK-OS3_c-1.AA TKL-Unique 16-199 30 3.8e-34 117.88 In-house 3-218 (290) Show / Hide 
Range on Protein: 16-199
Range on HMM: 3-218/290
Sequence Identity: 30% (67 aa)

NYLGSGSAGLVHKGVLPSGQLVAIKHIDK-EKKA----DTFFQEVESLSKVR-HPNLVSLLGYCQ----SFEGYYLVYEFCANGNLWQWLF---------
| .|.|..| | ||. . |  |||| . . |..     ..|  ||  ..| . |||.| . |||     .   ...| |.|  |.|   |          
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

GDRPPLTWEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLNDN-----MEAKLSDFGLSKFITMEESHVFT--------EVKGTSGYLDPEYMSR
 .  .|... |...|.  |.|. .||.. .  ||||| |..|.|.. |     . .|..||||||| . .    ..        ...|.  .. || ...
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GQLTLASDIYSFGIVL
   | .  ||.|||||||
NFCQYSEKSDVYSFGIVL
Kinase RLCK-OS3_c-1.AA Ciliate-E2 12-208 20 4.6e-33 110.84 In-house 1-295 (365) Show / Hide 
Range on Protein: 12-208
Range on HMM: 1-295/365
Sequence Identity: 20% (61 aa)

FSSENYLGSGSAGLVHKGVL------------------------PSGQLVAIKHIDK-----EKKADTFFQEVE----------SLSKVRHPNLVSLLGY
.   . .|.|. | | |.                            ....|.| . |      |. .  ..|..           |... |||.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CQ--SFEGYYLVYEFCANGNLWQ-----WLFG------DRPPLTWEERLNIALGSAR---------------GLFFLHTNVGGAIIHRDVKPTNILLNDN
 |  . . .||| |.|  |.|..     ...       |  ..|..|...|    ..               .| .|| .    ||||| || |||.   
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF---

MEAKLSDFGLSKFITME---ESHVFTEVK----------------------------GTSGYLDPEYMSRGQ---------LTLASDIYSFGIVLLQLVS
   |..||||||... .   ..| . . |                            || ||. ||  ....          . ..||.|.|..| ....
--IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GRKP
|. |
GKPP
Kinase RLCK-OS3_c-1.AA S_TKc 12-258 22 7e-33 116.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-258
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

FSSENYLGSGSAGLVHKGVLPS-GQLVAIKHIDKEKKADTFFQEVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCAN--GNLWQWLFGDRPP-----LT
.   . .|.|. | |.|..  . |..|||| |.     ... .|.. |.| .|||.| |....|. . .|.| |.| .  |.| . .   ...     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITMEESHVFTEVKGTSGYLDPEYMSRGQLTL-ASDIYSFGIVLLQL
  .   ..   ...| ..| . |  |||||.|| ||||..  . |..||||....        | . ||  |. || .   . .  ..|..|.|..|  .
E-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VSGRKPIDFNLQHRYSLVRAVSGNHFTQSSLPFLLSQAQRV--AERGSDIHKFA-------DPLM
..|. | . ..|  . ...       ... .  ....  ..  ..| .    ..       .| .
LCGYPPFP-QMQMMFKKIG-------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK-OS3_c-1.AA TK 12-208 15 4.6e-31 100.78 In-house 1-394 (486) Show / Hide 
Range on Protein: 12-208
Range on HMM: 1-394/486
Sequence Identity: 15% (61 aa)

FSSENYLGSGSAG---LVHKGVLPSG--------------------------QLVAIKHIDKE--KKADTFFQ--------------EVESLSKVR----
   .. ||.|  |    |.|| . ..                          . ||.| . ..    .. ||.              |.| ... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVSLLGYCQSFEG------------YYLVYEFCANGN----LWQWLFGDRPP--------------------------------------------
 |||.|.|.|.|   |.            ...| |....|.    | ..|   ||.                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWEERLNIALGSARGLFFLHTN--VGG--AIIHRDVKPTNILLNDNME-----------AKLSDFG--
                               || ...| ...  |.|. .|| .    .   ..|||.   |.|...|.            .|..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSKFITMEESHVFTEVKGTSG-------------------------YLDPEYMS---------RGQLTLASDIYSFGIVLLQLVS-GRKP
      |.. |  ..  . .. .||..                         .. || .           |  | .||..|||...  ... |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase RLCK-OS3_c-1.AA STE 12-206 20 2.7e-30 104.24 In-house 1-265 (359) Show / Hide 
Range on Protein: 12-206
Range on HMM: 1-265/359
Sequence Identity: 20% (55 aa)

FSSENYLGSGSAGLVHKGVLP----------------SGQLVAIKHIDKEK-------------------KADTFFQEVESLSKVR--HPNLVSLLGYCQ
.     .|.|. | |.|..                  .|...||| ...|.                   . . . .|.. ..| .  ||| |  .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SF-------EGYYLVYEFCANGNLWQWLF---GDRPPLTW---------EERL-NIALGSARG-LFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFG
         .  ... |....| | . .    |   ||.          |. .  |.    .| | .|| .    |||||.|| ||||     .||.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKFITME--------------ESH-VFTEVKGTSGYLDPEYMSR------GQLTLASDIYSFGIVLLQLVSGR
... .| .               .    . . ||  .  || ...      .. .  .||.|.|.... .. |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase RLCK-OS3_c-1.AA LRRK 12-210 24 4.3e-30 103.64 In-house 1-284 (351) Show / Hide 
Range on Protein: 12-210
Range on HMM: 1-284/351
Sequence Identity: 24% (70 aa)

FSSENYLGSGSAG-LVHKGVLPS---------------------------GQLVAIKHIDKE------------------------------------KK
. .|. .|.|. | .|... . .                           .| |||| ....                                    ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ADTFFQEVESLSKVRHPNLVSLLGYCQSFEGYYLVYEFCANGNLWQWLF---GDR-----PPLTWEERLNIALGSARGLFFLHTNVGGA--IIHRDVKPT
  .| .||  .|. .|||.|||.|.|  .. . .| |.  .|.| . |.    |.     . ..|  .| |||  |.|. .|| .      ||||| |. 
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH---NPPIIHRDLKSP

NILL---N---------DNMEAKLSDFGLSK-FITMEESHVFTEVKGTSGYLDPEYMSRG---QLTLASDIYSFGIVLLQLVSGR-KPID
||||   .         ... ||..|||.|  | .   . |.  . |. |.. || |  .   . |  .|.||||..|  |....  | |
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase RLCK-OS3_c-1.AA Pkinase_Tyr 18-199 28 6.9e-27 91.68 Pfam 7-204 (270) Show / Hide 
Range on Protein: 18-199
Range on HMM: 7-204/270
Sequence Identity: 28% (58 aa)

LGSGSAGLVHKGVLP-----SGQLVAIKHIDKEKKADT------FFQEVESLSKV-RHPNLVSLLGYCQ-SFEG--YYLVYEFCANGNLWQWLFGD---R
||.|. | |.||..       .. ||.| . ||.  .       |..|.. ...  .|||.|.|.| |    |   .|.| |....|.|   |      .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

PPLTWEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITMEESH-VFTE-----VKGTSGYLDPEYMSRGQLTLASDIY
.||| .. |....  |.|. .|. .    .||||.   |.|...|. .| .||||.. |. ..   . ..     .| ..    || .. |  | .||..
QPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMA----PECINYGKFTTKSDVW

SFGIVL
|||...
SFGVLM
Kinase RLCK-OS3_c-1.AA TyrKc 12-295 23 1.3e-17 62.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-295
Range on HMM: 1-280/280
Sequence Identity: 23% (75 aa)

FSSENYLGSGSAGLVHKGVLPSGQLVAIKHIDKEKKADTFFQEVESLSKV--RHPNLVSLLGYCQSF-------EGYYLVYEFCANGNLWQWLFGDRPPL
 . .  ||.|  | |.||..   . ||.| . ...    | .| . ..|.  .|||.| |.|.| .        | ...| |....|.| . |   || |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TWEERLNIALGSARGLFFLHTNVGGAIIHRDVKPTNILLNDNMEAKLSDFGLSKFITME-------ESHVFTE---VK--GTSGYLDPEYMSRGQLTLAS
.... |....  |.|  .|| .    .||||    |.|...|  .| ||||||..|. .       .  . .|    |       . || .  |  | .|
CMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIYSFGIVLLQLVS-GRKPID------FNLQHRYSLVRAVSGNHFTQS----SLPFLLSQAQRVAERGSDIHKFADPLMDRKFSAAAALKIVEIAVFCTA
|..|||...  . . | .|         . |. . .|..       ..    |                             |   .  .. .|   | .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------F-VCCPDEMYQIMKQCWH

QSSNDRPTIKEINETL
   .|||| .|| | .
EDPEDRPTFSEIHECF
Kinase RLCK-OS3_c-1.AA ULK 129-208 25 6.5e-16 52.1 In-house 151-255 (329) Show / Hide 
Range on Protein: 129-208
Range on HMM: 151-255/329
Sequence Identity: 25% (27 aa)

IIHRDVKPTNILLNDN------------MEAKLSDFGLSKFIT-M-EESHVFTEVK------GTSGYLDPE-YMSRG---QLT-LASDIYSFGIVLLQLV
||||| || |||....            . .|..|||..|...   .|  ...  .      ||  |  |.  ...|   . .   .||.|.|... ...
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGRKP
 |. |
YGKPP
Kinase RLCK-OS3_c-1.AA ULK 129-208 25 7.3e-16 52.83 In-house 147-251 (324) Show / Hide 
Range on Protein: 129-208
Range on HMM: 147-251/324
Sequence Identity: 25% (27 aa)

IIHRDVKPTNILLNDN------------MEAKLSDFGLSKFIT--MEESHVFTEVK------GTSGYLDPE-YMSRG---QLT-LASDIYSFGIVLLQLV
||||| || |||....              .|..|||..|..   ..|  .... .      ||  |  |.  ...|   . .   .||.|.|... ...
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

SGRKP
 |. |
YGKYP
Kinase RLCK-OS3_c-1.AA ULK 12-91 26 1e-15 52.31 In-house 1-104 (324) Show / Hide 
Range on Protein: 12-91
Range on HMM: 1-104/324
Sequence Identity: 26% (28 aa)

FSSENYLGSGSAG-LVHKGV-LPS---GQLVAIKHIDKEKKAD------------TFFQEVESLSKVR---HPN--LVSLLGYCQSFEG--YYLVYEFCA
..  . ||.|| |  |.||    .   .|.||.| ||| |  .             . .|.. . |     |||   | |. ....     .|...|.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGNL
 |.|
GGDL
Kinase RLCK-OS3_c-1.AA ULK 12-91 25 3.7e-15 49.44 In-house 1-107 (329) Show / Hide 
Range on Protein: 12-91
Range on HMM: 1-107/329
Sequence Identity: 25% (27 aa)

FSSENYLGSGSAGLVHKGV-LPS----GQLVAIKHIDKEK-KADT-----------FFQEVESLSKVR--------HPNLVSLLGYCQSFEG--YYLVYE
..  . ||.|| | |.||    .    ...||.| |||.| . .            . .|.. . |          ||| | |. ....     .|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCANGNL
.|  |.|
YCNGGDL
Kinase RLCK-OS3_c-1.AA TK 277-295 36 0.032988 2.34 In-house 468-486 (486) Show / Hide 
Range on Protein: 277-295
Range on HMM: 468-486/486
Sequence Identity: 36% (7 aa)

CTAQSSNDRPTIKEINETL
| .   .|||| ... | |
CWHYDPEDRPTFSQLHEQL
Kinase RLCK-OS3_c-1.AA LRRK 277-297 23 0.064891 2.54 In-house 331-351 (351) Show / Hide 
Range on Protein: 277-297
Range on HMM: 331-351/351
Sequence Identity: 23% (5 aa)

CTAQSSNDRPTIKEINETLEA
| ..  ..||.  .| ..|. 
CWQHDPKKRPHFSQIVKRLSQ
Kinase RLCK-OS3_c-1.AA TKL-Unique 277-295 31 0.19888 1.02 In-house 272-290 (290) Show / Hide 
Range on Protein: 277-295
Range on HMM: 272-290/290
Sequence Identity: 31% (6 aa)

CTAQSSNDRPTIKEINETL
| .. . .||.  || . |
CWHHDPSQRPSFDEIIHRL
Kinase RLCK-OS3_c-1.AA Pkinase_Tyr 279-295 47 3.120117 1.41 Pfam 254-270 (270) Show / Hide 
Range on Protein: 279-295
Range on HMM: 254-270/270
Sequence Identity: 47% (8 aa)

AQSSNDRPTIKEINETL
..  .|||| .|| | |
HYDPEDRPTFSEIHEQL