Gene RLCK3_b-2 (S.moellendorffii)

RLCK3_b-2

Species: S.moellendorffii
Alias: RLCK3_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK3

Sequence

Name Sequence Type Origin Length Description Download
RLCK3_b-2.AA Protein None 423 None Fasta, JSON
RLCK3_b-2.NA RNA None 1272 None Fasta, JSON
RLCK3_b-2.kin_dom Protein Kinase Domain None 326 None Fasta, JSON

Protein domain

Protein domains of RLCK3_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK3_b-2.AA IRAK 88-310 37 9.9e-60 204.75 In-house 1-233 (317) Show / Hide 
Range on Protein: 88-310
Range on HMM: 1-233/317
Sequence Identity: 37% (92 aa)

FHRTHWLGEGGFGCVYKGFIKVNR-TDGTESKVEVAVK---QLNGKGLQGHKE-WLS---EIRYLGVVDDPNLVKLIGYCLEDDPRGVQMLLVYEFMPKG
||. . .|||||||||.| .| .  .        .|||   . .     .|..  ..   |....     ||.| | |||.| .    .  |||..|| |
FHKDNRIGEGGFGCVYRGQWKNTTGI--------YAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQ----CHCLVYPYMPNG

SLEGHLFRRG---PP-VLPWEARVKIALGTARGLAYLHEEL-QIQIIYRDFKTSNILLDDSFGPKLSDFGLARLG---PEGGDSHV----TTAVVGTVGY
|||  |  ..   ||  |.|  |..|..|||.|. .||.    . || .| |..|||||. | ||..||||.| |   ..  .. .    |  |.||  |
SLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWY

AAPEYVH--TGHLTAKSDVWSFGVVLLELLTGRKALDKNRPKNEQ
 .||.    .| || |.|| |||.||||.|||..| ...||....
MPPEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYY
Kinase RLCK3_b-2.AA TKL 94-371 21 3.5e-57 196.28 In-house 1-364 (364) Show / Hide 
Range on Protein: 94-371
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGEGGFGCVYKGFIKV-----NRTDGTESKVEVAVKQLNGKGLQGH---------------------------KEWLSEIRYLGVVDDPNLVKLIGYCLE
.|.||||.||||  .      .   .  .  .||||... .  . .                           ..   ||. .   . ||.|...|||..
IGSGGFGEVYKGKWRGWGGKCP---S-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCC

DDPRG---------VQMLLVYEFMPKGSLEGHLFRRGPPVLPWEARVKIALGTARGLAYLHEEL-----QIQIIYRDFKTSNILLDDSFG----------
 ....          |. .|.|..|.|||. .|         |. |...||..|||..||| .        .||.|| |..|||.|. .           
PPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PKLSDFGLAR-LGPEGGDSHVTTA----------------VVGTVGYAAPEYV----------------HTGHLTAKSDVWSFGVVLLELLTGRKA
    .|..||||.| . ..|....  |.                ..|| .. |||                  . .  . |.||.|||.|| |.||... 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

LDKNRPKNEQRLLEWVKP-------YISTSRKFHLIMDPSLEG----HYPLQAAQKMASLAASCLTRQPKARPKMSALVEGL
     |  ..   ...         ..  ... .. ..|  .       . .. . |..|.  |    |..|| .. ... |
-----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RLCK3_b-2.AA Pkinase 88-362 23 5.7e-47 167.17 Pfam 1-282 (293) Show / Hide 
Range on Protein: 88-362
Range on HMM: 1-282/293
Sequence Identity: 23% (75 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQLNGKGLQGHKEW-----LSEIRYLGVVDDPNLVKLIGYCLEDDPRGVQMLLVYEFMPKG---
.|.   .|.|.||||||.  | ..        .||||... .  . ....     ||||...  .. || |.|.... .    .  . .| |....|   
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYV

-SLEGHLF-RRGPPV-LPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDDSFGP----KLSDFGLARLGPEGGDSHVTTAVVGTVGYAAPEY
 .|  ..  .|. .. ....   .... ..|||.|.|..    ||.|| | .|||.|.   .    |..|||||..      .. .| ..|| .|.||| 
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV

VH-TGHLTAKSDVWSFGVVLLELLTGRKALDKNRPKNEQRLLEWVK----PYISTSRKFHLIMDPSLEGHYPLQAA-------------------QKMAS
.    . . |.|.||.|..| |.|.||             .. . .    . ..   .. .||.| |. ..|                       . . .
IRGGQYYGPKVDMWSCGCILYEMLCGR-------------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LAASCLTRQPKARP
.  .||.. || ||
FIKWCLCKDPKKRP
Kinase RLCK3_b-2.AA S_TKc 88-375 23 1.1e-42 149.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 88-375
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQLNGKGLQGHKEWLSEIRYLGVVDDPNLVKLIGYCLEDDPRGVQMLLVYEFMPK--GSLEGHL
..    .|.|.||.|||.  |        .. .||.|...       .  ..||. |   . ||.|||.... .       . .| |...   |.|  ..
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYI

FRRGPPV----LPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDDSFGPKLSDFGLARLGPEGGDSHVTTAVVGTVGYAAPEYVHTGHLTAK
 .||..     .|     ...  ....|.|.|.    .||.|| | .|||||.    |..||||||.          | ..||  | ||| .  |. ..|
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCK

SDVWSFGVVLLELLTGRKALDKNRPKNEQRLLEWVKPYISTSRKFHLIMDPSLEGHYPLQAAQKMASLAASCLTRQPKARPKMSALVE-----GLKQVL
.|.||.|..| |.|.|.   .     ..|.... ..                          . . ..   ||.. |. ||    . .      . . .
CDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK3_b-2.AA TK 88-296 17 1.6e-37 122.8 In-house 1-389 (486) Show / Hide 
Range on Protein: 88-296
Range on HMM: 1-389/486
Sequence Identity: 17% (67 aa)

FHRTHWLGEGGFG---CVYKGFIKVNRTD------------------GTESKVEVAVKQLNGKGLQGHKEWLS-----------------EIRYLG--VV
 .  . |||| ||    ||||  .  . .                  ... |..||||.|  .  .  .| .                  |.  .   . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DDPNLVKLIGYCLEDDPR--------GVQMLLVYEFMPKGS----LEGHLFRRGPP--------------------------------------------
. ||.|.|.|.|....|.        .  ...| |.||.|.    |  .| .. |.                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------VLPWEARVKIALGTARGLAYLHEELQI----QIIYRDFKTSNILLDDSFG-----------PKLSDFG--
                               |. . .. ...  |.|..||| ....    ... ||  . |.|....              |..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH-SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARLGPEGGDSHVTTAVVGTVG------------------------YAAPEYVH---------TGHLTAKSDVWSFGVVLLELLT
      |||  ....| ....   ....                        . ||| .          .|. | |||||||||.. |..|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase RLCK3_b-2.AA Dicty4-Unclassified 88-297 31 9.3e-35 116.44 In-house 1-204 (263) Show / Hide 
Range on Protein: 88-297
Range on HMM: 1-204/263
Sequence Identity: 31% (69 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQLNGKGLQGH----KEWLSEIRYLGVVDDPNLVKLIGYCLEDDPRGVQMLLVYEFMPKGSLEG
      .|.| |  |.||  |           .|||| .|    .      .. . |.  || .  |||||. |||.        |  | |||.|| |  
IQIDQFIGKGHFSKVHKGNWKGK---------DVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFE

HLF-----RRGPPVLPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDDSFGPKLSDFGLARLGPEGGDSHVTTAVVGTVGYAAPEYVHTGHL
        .  |  |     .|.|.  |.|...||      .| || | ||||.|  |  |  |||..|   .       |.. ||.   .||       
VIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISR---VIDFNFNMTTIAGTPKWESPECLMHESY

TAKSDVWSFGVVLLELLTG
. ||||.|....| ||.||
NQKSDVYSYAMMLYELATG
Kinase RLCK3_b-2.AA TyrKc 88-371 26 3.3e-31 110.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 88-371
Range on HMM: 1-280/280
Sequence Identity: 26% (80 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQLNGKGLQGHKEWLSEIRYLGVV--DDPNLVKLIGYCLED-------DPRGVQMLLVYEFMPK
 .  . |||| || ||||  |          ..|||| |.      ... ..|.| .  .  . ||.|.|.|.|...       .|    ...| |.||.
ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP----LMIVMEYMPH

GSLEGHLFRRGPPVLPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDDSFGPKLSDFGLARLGPEG------GDSHVTT---AVV--GTVGY
|.|  .| ...|  |...  .....  |.| .|||.    ..| ||  . |.|... .  | |||||.| . ..      .|  ...          .  
GDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

AAPEYVHTGHLTAKSDVWSFGVVLLELLTGRKALDKN---RPKNEQRLLEWVKPYISTSRKFHLIMDPSLEGHYPLQAAQKMASLAASCLTRQPKARPKM
 |||   .|  | |||||||||.. |..|  .    .   .... |...|.||      .  .    | .   .   . ..| ..  .|  ..|. || .
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS--F-VCCPDEMYQIMKQCWHEDPEDRPTF

SALVEGL
|...| .
SEIHECF
Kinase RLCK3_b-2.AA TK-Unique 88-296 27 1.7e-30 102.43 In-house 1-234 (294) Show / Hide 
Range on Protein: 88-296
Range on HMM: 1-234/294
Sequence Identity: 27% (65 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKV-EVAVKQLN-GKGLQGHKEWLSEIRYLGVVD-DPNLVKLIGYCLEDDPRGVQMLLVYEFMPKGSLEGH
.     .||| ||.|..|  .| .......|   ||||.|. .  .. ... |.||. .  ..  ||.|...|.| ..|    ......|..|.|.|...
LEVGDVIGEGAFGQVWRG--EVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD---EPWMIIMEYCPCGNLQHY

LFRRGPP---------------VLPWEAR---VK------IALGTARGLAYLHEELQIQIIYRDFKTSNILLDDSFGPKLSDFGLARLGPEGGDSHVT-T
| ...|.               . | . |   ..      .| . |.|..||.. .  .|..||  ..|.|| . .  |..|||.|| .  .|.   . .
LRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLAS-QRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCS

AVVGTVGYAAPEYVH--TGHL-TAKSDVWSFGVVLLELLT
     . . |||.    .|.  | |||||||||.. |..|
QGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase RLCK3_b-2.AA Dicty4 88-297 30 1.8e-30 98.95 In-house 1-213 (277) Show / Hide 
Range on Protein: 88-297
Range on HMM: 1-213/277
Sequence Identity: 30% (69 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQL--NGKG--LQGHKEWLSEIRYLGVVDDPNLVKLIGYCLEDDPRGVQ--MLLVYEFMPKGSL
  ..  .|.|.|| ||||  .           ||||| |  .  .  .   .| . |.  ..    ||.... |.|.   ||     |. | |.||||.|
INIEQRIGKGSFGEVYKGTWRGK---------EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTA--PRSHPGKMCIVTEYMPKGNL

EGHLFRR------GPPVLPWEARVK---IALGTARGLAYLHEELQI-QIIYRDFKTSNILLDDSFGPKLSDFGLARLGPEGGDSHV-TTAVVGTVGYAAP
.  | .           |.|. . .   .|. .|||...||.   .  || || |..|.| |...  | .||||...  .. |    .....||... ||
Y-SLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC--CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAP

EYVHTGHLTAKSDVWSFGVVLLELLTG
|       . |.|| ||| || |.||.
EVMMHQPYNEKADVYSFGIVLWEILTR
Kinase RLCK3_b-2.AA TKL-Unique 90-297 29 3.3e-30 103.82 In-house 1-224 (290) Show / Hide 
Range on Protein: 90-297
Range on HMM: 1-224/290
Sequence Identity: 29% (68 aa)

RTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQLNG---KGLQGHKEWLSEIRYLGVVD-DPNLVKLIGYCLEDDPRGVQMLLVYEFMPKGSLEGHL
    .||||.| ||||  .         . .||.||..    . ..  .|  .|.. . . .  ||.|...|||  . .   .| .| |..| |||  .|
FWNKIGEGGYGQVYKGKWR---------GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL

FR--------RGPPVLPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDDS-----FGPKLSDFGLARLGPEGGDSHVT-------TAVVGTV
 .        .    |... |||.|.  |.|. ||| .    || || |.||.|.|       .  |..||||...     .. ..       . ..|. 
HQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF

GYAAPEYVHT--GHLTAKSDVWSFGVVLLELLTG
 ..|||       . . ||||.|||.|| |..|.
RWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase RLCK3_b-2.AA STE 88-298 23 5.9e-29 99.44 In-house 1-265 (359) Show / Hide 
Range on Protein: 88-298
Range on HMM: 1-265/359
Sequence Identity: 23% (65 aa)

FHRTHWLGEGGFGCVYKGFIK----VNRTDGTE-----SKVEVAVKQLN---GKGLQGH------------KEW---LSEIRYLGVVD--DPNLVKLIGY
. .   .|.|.|| |||.  .     .   | .     ... .|.||.|    .  . .            .|.   | ||. .   .   || || .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

CLEDDPR---GVQMLLVYEFMPKGSLE---GHLFRRGPP---------VLPWEARVKIALGTARG-LAYLHEELQIQIIYRDFKTSNILLDDSFGPKLSD
.. ...    . .  .. |.|. |||.    | . .| |         ..| .   .|.  . .| |.|||.     || || | .||||      ||.|
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCD

FGLAR-LGPEGG------------DSH-VTTAVVGTVGYAAPEYVHT------GHLTAKSDVWSFGVVLLELLTGR
||..  | ...             ..   .. .|||  . ||| .        .. ..|.|.||.| ...|..||.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase RLCK3_b-2.AA MLK 88-298 28 1.3e-28 96.49 In-house 1-233 (291) Show / Hide 
Range on Protein: 88-298
Range on HMM: 1-233/291
Sequence Identity: 28% (70 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTE-SKVEVAVKQLN----GKGLQG--HKEWLSEIRYLGVVDDPN----LVKLIGYCLEDDPRGVQMLLVYEFM
.   .|.|.|.|| |.||  .     ... .  .||||. .     |.  .   ..   |.| | ... ||     ... | ||..   . . ..| |..
IQFHEWIGSGSFGKVWKGRWR-----NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQP---PCHFCIVMEYC

PKGSLEGHL--FRRGPP----------VLPWEARVKIALGTARGLAYLHEELQIQIIYRDFKTSNILLDD------SFGPKLSDFGLARLGPEGGDSHVT
..|||   |   | ..           | . .  ...||  |||..|||.... .|| || | .|||.|.          | .|||..|      | | .
EGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR------DWHQM

----TAVVGTVGYAAPEYV---HTGHLTAKSDVWSFGVVLLELLTGR
    .   ||. . |||       .  . |.||||.|||| |.||..
CTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase RLCK3_b-2.AA LRRK 150-302 31 2.2e-24 83.14 In-house 117-284 (351) Show / Hide 
Range on Protein: 150-302
Range on HMM: 117-284/351
Sequence Identity: 31% (57 aa)

PNLVKLIGYCLEDDPRGVQMLLVYEFMPKGSLEGHLF--RRGP-----PVLPWEARVKIALGTARGLAYLHEELQIQ--IIYRDFKTSNILLDDSFGP--
||.|.|.|.|..  |    . .| |..| |.|  .|.  .. .     ....|  . ||||  |.|..|||        ||.|| |. ||||  |  .  
PNIVSLKGFCIH--P----LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSPNILLWSSPQNHS

----------KLSDFGLAR----LGPEGGDSHVTTAVVGTVGYAAPEYVHTG---HLTAKSDVWSFGVVLLELLTGR-KALD
          |..|||. |    ....     |.  .||. |. ||| .  .     | |.|. |||..| ||||..  . |
PNYPNAHVCAKIADFGISRMFQCFHMG-----VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase RLCK3_b-2.AA Pkinase_Tyr 88-214 29 5.7e-24 81.81 Pfam 1-129 (270) Show / Hide 
Range on Protein: 88-214
Range on HMM: 1-129/270
Sequence Identity: 29% (40 aa)

FHRTHWLGEGGFGCVYKGFIKVNRTDGTESKVEVAVKQL-NGKGLQG--HKEWLSEIRYLGVV-DDPNLVKLIGYCL-EDDPRGVQMLLVYEFMPKGSLE
 .  . |||| || ||||  |    |. . |..|||| | .|   .   ... ..|.. .    . ||.|.|.| |. ...|   |...| |.||.|.| 
ITFGKKLGEGAFGEVYKGTWKG---DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLL

GHLFRR--GPPVLPWEARVKIALGTARGLAYLHE
 .| ..  ... |. .  .....  |.|..||..
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase RLCK3_b-2.AA Pkinase_Tyr 229-299 35 1.7e-08 29.41 Pfam 141-213 (270) Show / Hide 
Range on Protein: 229-299
Range on HMM: 141-213/270
Sequence Identity: 35% (26 aa)

NILLDDSFGPKLSDFGLARLGPEGGDS-HVTTAVVGTVGYAAPEYVHTGHLTAKSDVWSFGVVLLELLT-GRK
|.|.....  | .||||||.  . .   ....     .   |||  ..|  | |||||||||.. |..| |..
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQ
Kinase RLCK3_b-2.AA TK 346-371 34 0.002278 6.3 In-house 461-486 (486) Show / Hide 
Range on Protein: 346-371
Range on HMM: 461-486/486
Sequence Identity: 34% (9 aa)

MASLAASCLTRQPKARPKMSALVEGL
.. |  .|  ..|. || .|.|.| |
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RLCK3_b-2.AA LRRK 346-373 35 0.002306 7.74 In-house 324-351 (351) Show / Hide 
Range on Protein: 346-373
Range on HMM: 324-351/351
Sequence Identity: 35% (10 aa)

MASLAASCLTRQPKARPKMSALVEGLKQ
. .|  .| . .|| ||..|  |. |.|
YQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase RLCK3_b-2.AA LRRK 88-127 19 0.00269 7.5 In-house 1-60 (351) Show / Hide 
Range on Protein: 88-127
Range on HMM: 1-60/351
Sequence Identity: 19% (12 aa)

FHRTHWLGEGGFG-CVYKGFIKVNR---------------------TDGTESKVEVAVKQLN
. .   .|.||||  ||..  |...                      ..  .  .||.|..|
LKIEEQIGRGGFGTFVYRA--KWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN
Kinase RLCK3_b-2.AA IRAK 341-371 19 0.011797 5.43 In-house 287-317 (317) Show / Hide 
Range on Protein: 341-371
Range on HMM: 287-317/317
Sequence Identity: 19% (6 aa)

QAAQKMASLAASCLTRQPKARPKMSALVEGL
. ...|...|  |. .  . |..|   .. |
NMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase RLCK3_b-2.AA Pkinase_Tyr 339-371 27 0.038882 7.86 Pfam 238-270 (270) Show / Hide 
Range on Protein: 339-371
Range on HMM: 238-270/270
Sequence Identity: 27% (9 aa)

PLQAAQKMASLAASCLTRQPKARPKMSALVEGL
|  . ... .|  .|   .|. || .|...| |
PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RLCK3_b-2.AA TK-Unique 344-371 28 0.041852 3.2 In-house 267-294 (294) Show / Hide 
Range on Protein: 344-371
Range on HMM: 267-294/294
Sequence Identity: 28% (8 aa)

QKMASLAASCLTRQPKARPKMSALVEGL
. | .|  ||... |. ||  ....  |
HEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RLCK3_b-2.AA Dicty4-Unclassified 348-371 29 0.063583 2.33 In-house 240-263 (263) Show / Hide 
Range on Protein: 348-371
Range on HMM: 240-263/263
Sequence Identity: 29% (7 aa)

SLAASCLTRQPKARPKMSALVEGL
.|   |.   |. || |   .. |
KLIKWCWHNDPNKRPTMNQIIQYL
Kinase RLCK3_b-2.AA MLK 346-371 26 0.112876 1.74 In-house 266-291 (291) Show / Hide 
Range on Protein: 346-371
Range on HMM: 266-291/291
Sequence Identity: 26% (7 aa)

MASLAASCLTRQPKARPKMSALVEGL
...|   |    |. ||...  |. |
WKKLMKQCWNQDPHKRPSFRQIVQHL