Gene RLCK33_a (S.moellendorffii)

RLCK33_a

Species: S.moellendorffii
Alias: RLCK33_a
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK33

Sequence

Name Sequence Type Origin Length Description Download
RLCK33_a.AA Protein None 601 None Fasta, JSON
RLCK33_a.NA RNA None 1806 None Fasta, JSON
RLCK33_a.kin_dom Protein Kinase Domain None 213 None Fasta, JSON

Protein domain

Protein domains of RLCK33_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK33_a.AA TKL 243-449 23 5.5e-52 179.03 In-house 1-284 (364) Show / Hide 
Range on Protein: 243-449
Range on HMM: 1-284/364
Sequence Identity: 23% (69 aa)

IGEGSYGHVYKGTLHR----------TNVAVKVLRHDSWQGPQEFEQE--------VRKLTRISKISNKHGKIKVEVL---SRLHHPHIVLLLG------
||.|..| ||||...           . ||||... .. .   . .||              ... . .  . ..|..   |||.||.||...|      
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSD-M-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP

---------GNPEKKCLVYEYLENGSLEDRLFCKDDSPPISCLTRYQIAVEVGTALLFLHKAKP-----QPIVLRDLKPSNILLDKNYN-----------
         |.. . |.|.|| ..|||...|             | ..| ..  .. .||  .|      ||. ||||..|||.|.|..           
CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---SKISDVGLARFMPGDA-----------------TSVRSTSPVGTFAYIDPEY----------------QREGSFNAKSDVFAFGIILLQLLT
    ||.| ||.||| ..                  .. .. ...||...  ||                 ....... |.||..|||.|  .||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILT
Kinase RLCK33_a.AA IRAK 299-449 39 1.5e-36 127.1 In-house 54-219 (317) Show / Hide 
Range on Protein: 299-449
Range on HMM: 54-219/317
Sequence Identity: 39% (65 aa)

VEVLSRLHHPHIVLLLG--GNPEKKCLVYEYLENGSLEDRLFCKD-DSPP--ISCLTRYQIAVEVGTALLFLHKAKPQ-PIVLRDLKPSNILLDKNYNSK
..|..|..||.|| |.|    ... ||||.|. |||||||| | | . ||   |  .|  |.   . .. ||| . |  ||  .| |..|||||.. . |
LKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPK

ISDVGLARFM----PGDATSV---RSTSPVGTFAYIDPEYQR--EGSFNAKSDVFAFGIILLQLLT
|.| ||.||        ....   .    .|| .|  ||. |   |    |.||. ||| || .||
ICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLT
Kinase RLCK33_a.AA MLK 237-449 27 1.2e-34 117.68 In-house 1-231 (291) Show / Hide 
Range on Protein: 237-449
Range on HMM: 1-231/291
Sequence Identity: 27% (68 aa)

FSENNKIGEGSYGHVYKGTLHRTN-----VAVKVLRHDSWQGPQE-------FEQEVRKLTRISKISNKHGKIKVEVLSRLHHPHIVLLLGG---NPEKK
. .  .||.||.| |.||. . ..     ||||  |..     ..       ||.|.|.| ..|.  |              || |. ..|.   .| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNN--------------HPCIIQFYGVCLQPPCHF

CLVYEYLENGSLEDRLFCKDDSPP-----------ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLD------KNYNSKISDVGLARFMPG
|.| ||.|.||| . |  ... .            ..     ..|. .  .. .||. .|.||. ||||..|||.|      .. . ||.| |..|..  
CIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQ

D-ATSVRSTSPVGTFAYIDPEY--Q-REGSFNAKSDVFAFGIILLQLLT
  ..    .|  ||.|.  ||   | |.. .. |.||. .|..| ..||
MCTN---MMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase RLCK33_a.AA Pkinase 237-453 27 1.7e-30 108.88 Pfam 1-211 (293) Show / Hide 
Range on Protein: 237-453
Range on HMM: 1-211/293
Sequence Identity: 27% (63 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLRHDSWQGPQEFEQEVRKLTRISKISNKHGKIKVEVLSRLHHPHIVLLLGGN--PEKKCLVYEYLENG-
.    |||.||.| |||.. . |.  ||||... .  . ... .. .|                .... ||.||.|| |..    . . ..| ||.|.| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL

---SLEDRLFCKDDSPPI--SCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS----KISDVGLARFMPGDATSVRSTSPVGTFAYID
   .| |..   ... ..  |  .   .. ..  .| ..|.     |. |||||.|||.|.|..     ||.| |||...     ..  |...||  |. 
YVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMA

PEYQR-EGSFNAKSDVFAFGIILLQLLTATSP
||  |       |.|....|.|| ..|.   |
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase RLCK33_a.AA LRRK 301-449 30 4.9e-27 92.69 In-house 110-277 (351) Show / Hide 
Range on Protein: 301-449
Range on HMM: 110-277/351
Sequence Identity: 30% (53 aa)

VLSRLHHPHIVLLLGGNPEKKCLVYEYLENGSLEDRLFCKDDSP------PISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILL---D-----
..|.|.||.|| |.|   .  |.| ||. .|.| ..|. |  ..       ||  ....||...  .. .||...| ||. ||||. ||||   .     
IMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNILLWSSPQNHSP

----KNYNSKISDVGLARFMPGDATSVRST---SPVGTFAYIDPEYQREG---SFNAKSDVFAFGIILLQLLT
     ... ||.| |. | |    ......     ||.. .  ||  |..   ... |.|...||.||  |||
NYPNAHVCAKIADFGISR-MF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase RLCK33_a.AA RIPK 243-453 28 2.1e-26 86.99 In-house 1-227 (290) Show / Hide 
Range on Protein: 243-453
Range on HMM: 1-227/290
Sequence Identity: 28% (68 aa)

IGEGSYGHVYKGT--LHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNKHGKIKVEVLSRLHHPHIVLLLGGNPEK--------KCLVYEYLENGS
.| |. | |.| .   ... ||.|.      . .   .||. .. .  |. .|           | . ||| ..|   ..          .| || ||||
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMYQKEEAKHMHK-----------LRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGS

LEDRLFCKD--DSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--AT---------SVRSTSPVGTFA
|.. |  |     .|.    |  . .|.  .  .||  .| ||  |||||.|||.| |.. ||.| ||| .| .    .         | .|  . || .
LWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNP-PIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLS

YIDPEYQREGSFNA------KSDVFAFGIILLQLLTATSP
|..||  |..  ..      |.||  |.|.. ..||   |
YMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase RLCK33_a.AA TKL-Unique 299-444 29 1.1e-24 84.08 In-house 46-218 (290) Show / Hide 
Range on Protein: 299-444
Range on HMM: 46-218/290
Sequence Identity: 29% (52 aa)

VEVLSRLH-HPHIVLLLGGNP----EKK--CLVYEYLENGSLEDRLF-------CKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNIL
| ....|| || ||.. |.        .  |.| ||.. ||| | |           .. ... . |...|  .  .. .||  .|  |  ||||.||.|
VNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFL

LDKN-----YNSKISDVGLARFMPGDATSVRS-------TSPVGTFAYIDPEYQRE--GSFNAKSDVFAFGIIL
.| |     .| ||.|.||..|   . ..  .       ....|.| .. ||  |     .. ||||..|||.|
VDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL
Kinase RLCK33_a.AA Dicty4 299-449 29 2e-23 75.12 In-house 49-212 (277) Show / Hide 
Range on Protein: 299-449
Range on HMM: 49-212/277
Sequence Identity: 29% (48 aa)

VEVLSRLHHPHIVLLLGG------NPEKKCLVYEYLENGSLEDRLFC------KDDSPPISCLTR-YQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILL
|. .. . ||.|.|..|       .|.| | | ||.  |.|.  |        . .... .  .|  ..|  .   .  ||   |  |. ||||..|.| 
VHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV

DKNYNSKISDVGLAR-FMPGDATSVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLT
|||.. |..| ||.. . ..   .   ....|| ..  ||  .. ..| |.||. |||.| ..||
DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILT
Kinase RLCK33_a.AA TK 237-449 17 1.9e-22 71.39 In-house 1-389 (486) Show / Hide 
Range on Protein: 237-449
Range on HMM: 1-389/486
Sequence Identity: 17% (70 aa)

FSENNKIGEGSYG---HVYKGTLHR---------------------------TNVAVKVLRHDSWQGPQEFEQ-------EVRKLTRISKISNKHG----
    .|.||| .|    ||||....                           | ||||.|. .. . ..||..       .              |    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDG--------------GEDFL

--KIKVEVLS--RLHHPHIVLLLG----GNP----------EKKCLVYEYLENGS----LEDRLF-----------------------------------
      ....   .|||.|| |.|    | |          |  ..| || ..|.    | | |                                    
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

------------------CKDDSPPISCLTRYQ-------------------IAVEVGTALLFLHKAKP---QPIVLRDLKPSNILLDKNYN--------
                   ||..||..    .|                   ... .  .. .||. .    | .| |||   |.|...|..        
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGC

---SKISDVG--------LARFMPGDATSVRSTSPVGT------------------------FAYIDPEYQREGS---------FNAKSDVFAFGIILLQ
    ||.| |        ||| .. |   .|..|. ..                        . .  ||  ...          |  ||||..||. .  
GPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWE

LLT
..|
IFT
Kinase RLCK33_a.AA CZAK 299-453 30 1.4e-20 71.61 In-house 51-221 (279) Show / Hide 
Range on Protein: 299-453
Range on HMM: 51-221/279
Sequence Identity: 30% (53 aa)

VEVLSRLHHPHIVLLLG----GNPEKKCLVYEYLENGSLEDRLFCKDDSPPISC--LTRYQIAVEVGTALLFLHK-AKPQPIVLRDLKPSNILLDKNYN-
| ..| | || .|  ||    ..|. .| | |. . |||  | .  | .  .      . ..|. .     .||   || ||. |||  .||||| .|  
VSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSL--RRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTP

------------SKISDVGLARFMPGDATSVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLTATSP
             ||.| || | |   ..    |. .|  ..  ||     ..  |.||. ||.||  ..|   |
KNPVVSSRQDIICKINDFGLSREMMEQPFEM--TQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQP
Kinase RLCK33_a.AA S_TKc 237-521 22 1.5e-19 72.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 237-521
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FSENNKIGEGSYGHVYKGTLHR--TNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNKHGKIKVEVLSRLHHPHIVLLLGGNP-EKKCLVYEYLEN--G
.   .|||.|..| |||.. ..    ||.|...                         .| .  ...|.. |||.|| |..    .. ..| ||...  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLG

SLEDRLFCKDDSPP---ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGDATSVRSTSPVGTFAYIDPEYQRE
.| |..  .   ..   ..  .   .. ..  || ..|. .   |. |||||.|||||.  . ||.| ||||..         |. .||  |. ||    
DLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--

GSFNA-KSDVFAFGIILLQLLTATSPVGIIHKVSTAVDQGHLMEILDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQ-MLETMNHLFR
 ...  |.|. ..|.||  .|.   |           ..  .....             ..  .  .| ..  ..||    .||  .. ..| . 
-GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK33_a.AA TyrKc 237-513 22 2.4e-16 41.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 237-513
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNKHGKIKVEVLSRL--HHPHIVLLLGG--NP-------EKKCLVY
 . . |.||| .| |||||.  ..||||.|..|.    ..| .| |                  ....|  |||.|| |.|    .       |  ..| 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREAR------------------IMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EYLENGSLEDRL-FCKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--------ATSVRS--TSP
|| ..|.| |.|  ....   ..  .  .... .     .||.    ... |||   |.|...|.  |||| ||.|.   |          ....   . 
EYMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

-VGTFAYIDPEYQREGSFNAKSDVFAFGIIL--LQLLTATSPVG------IIHKVSTAVDQGHLMEILDT-----SAGEWPLAAATQLACIGLNCAEVQR
 .       ||  ..| |. ||||..||. .  .  . .. . |          |   |.||. |.. .      .       . . .  | . | . . 
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDP

KNRPELENVLQML
..||  ... . .
EDRPTFSEIHECF
Kinase RLCK33_a.AA CAMK 242-338 16 4.1e-13 37.89 In-house 1-152 (425) Show / Hide 
Range on Protein: 242-338
Range on HMM: 1-152/425
Sequence Identity: 16% (27 aa)

KIGEGSYGHVYKGTLHRTN--------------VAVKVLRHD-------------------------SW---QGPQEFEQEVRKLTRISKISNKHGKIKV
..|.||.| |....  .|.              ||.|..  .                         .|   .  .....|.. . ....|.|       
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

EVLSRLHHPHIVLLLG--------------GNPEK--------KCLVY---EYLENGSLEDRLF
    .|.||.|. |.                . .|         ..|    || ..| | |.||
----KLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLF
Kinase RLCK33_a.AA CAMK 373-453 23 1.8e-12 35.75 In-house 200-333 (425) Show / Hide 
Range on Protein: 373-453
Range on HMM: 200-333/425
Sequence Identity: 23% (31 aa)

IVLRDLKPSNILLDKN-----------------YNSKISDVGLARFMPGDATSV---------------------RSTSPVGTFAYID-PEYQR------
|| ||||| |||||.|                 .| ||.| |.|......  .                        . ..|| .|.  ||  .      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EGSFNAKSDVFAFGIILLQLLTATSP
        .   . |.|. . |.||  .|. ..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP
Kinase RLCK33_a.AA IRAK 237-267 45 1.6e-10 33.63 In-house 1-33 (317) Show / Hide 
Range on Protein: 237-267
Range on HMM: 1-33/317
Sequence Identity: 45% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLR
|...|.|||| .| ||.| .. |   .||| |.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLK
Kinase RLCK33_a.AA Pkinase_Tyr 237-288 27 1.9e-09 32.65 Pfam 1-62 (270) Show / Hide 
Range on Protein: 237-288
Range on HMM: 1-62/270
Sequence Identity: 27% (17 aa)

FSENNKIGEGSYGHVYKGTLH------RTNVAVKVLRHDSWQG---PQEFEQEVRKLTRI-S
 . . |.|||..|.|||||..      .. ||||.|.... .     ..| .|.. .. . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH
Kinase RLCK33_a.AA TKL-Unique 241-282 44 2.1e-08 25.92 In-house 3-47 (290) Show / Hide 
Range on Protein: 241-282
Range on HMM: 3-47/290
Sequence Identity: 44% (20 aa)

NKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQ---EFEQEVR
||||||.|| ||||. ... ||.|..   . . ..   ||| ||.
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVN
Kinase RLCK33_a.AA Dicty4 237-266 50 5.1e-08 23.01 In-house 1-30 (277) Show / Hide 
Range on Protein: 237-266
Range on HMM: 1-30/277
Sequence Identity: 50% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVL
    ..||.||.| |||||   . ||||.|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKL
Kinase RLCK33_a.AA LRRK 237-266 15 1.4e-07 22.89 In-house 1-59 (351) Show / Hide 
Range on Protein: 237-266
Range on HMM: 1-59/351
Sequence Identity: 15% (9 aa)

FSENNKIGEGSYG-HVYKGTLHR----------------------------TNVAVKVL
. ....||.|..|  ||.... .                            ..||.|..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW
Kinase RLCK33_a.AA Pkinase_Tyr 299-442 28 5e-06 20.99 Pfam 54-202 (270) Show / Hide 
Range on Protein: 299-442
Range on HMM: 54-202/270
Sequence Identity: 28% (44 aa)

VEVLSRL-HHPHIVLLLGGNP--EKK---CLVYEYLENGSLEDRLFCK-DDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS
..... | |||.|| |.|     ..    ..| || ..|.| | |  . .| .|..  .  |.....  .. .|.  .   .. |||   |.|...|   
AKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVV

KISDVGLARFM-PGDAT-SVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGI
||.| |||| . . |    .|. ..        ||  ..| |. |||| .||.
KICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGV
Kinase RLCK33_a.AA CZAK 237-281 27 0.000396 11.07 In-house 1-51 (279) Show / Hide 
Range on Protein: 237-281
Range on HMM: 1-51/279
Sequence Identity: 27% (14 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQE------FEQEV
.     ||.| .| |||.    . ||.| .  ..     |      |. ||
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEV
Kinase RLCK33_a.AA IRAK 473-513 17 0.067979 2.7 In-house 277-317 (317) Show / Hide 
Range on Protein: 473-513
Range on HMM: 277-317/317
Sequence Identity: 17% (7 aa)

LDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQML
.|  .. .| . .  ...  . |..   ..|.. . |.| |
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Ubox RLCK33_a.AA Ubox 533-595 33 2.8e-21 77.93 SMART 1-72 (72) Show / Hide 
Range on Protein: 533-595
Range on HMM: 1-72/72
Sequence Identity: 33% (24 aa)

LFLCPILQEVMEYPVIASDG--YTYEYDAIIRWLQK---SDASPMTNLRL-ENKNLTPN---RVVRSAICEW
 |.|||  |.|. |||...|  .||.  .| .||..    . .|||.  | . ..|.||    .....| .|
EFCCPISLEIMKDPVILPSGKGQTYDRRCIEKWLKEGGQHGTCPMTRQPLPTHEDLIPNKTGHALKPKIQHW
U-box RLCK33_a.AA U-box 529-597 30 1.2e-15 47.18 Pfam 1-76 (81) Show / Hide 
Range on Protein: 529-597
Range on HMM: 1-76/81
Sequence Identity: 30% (23 aa)

AAPTLFLCPILQEVMEYPVIASDG-YTYEYDAIIRWLQK-----SDASPMT-NLRLENKNLTPNRVVRSAICEWRA
 .|  |.|||  | |  |||...| .||.  .| |.|..     .  .|.. .  |   .|.||. .. .| .| .
DIPDEFCCPIMWELMKDPVILPSGKITYDRSTIERHLLSEAWGRDHTDPFNGRQPLTHDMLIPNYELKEKIDHWLE