Gene RLCK4_a-2 (S.moellendorffii)

RLCK4_a-2

Species: S.moellendorffii
Alias: RLCK4_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK4

Sequence

Name Sequence Type Origin Length Description Download
RLCK4_a-2.AA Protein None 355 None Fasta, JSON
RLCK4_a-2.NA RNA None 1068 None Fasta, JSON
RLCK4_a-2.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of RLCK4_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK4_a-2.AA TKL 57-325 22 1.1e-59 204.59 In-house 1-364 (364) Show / Hide 
Range on Protein: 57-325
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

IGQGGFGTVYYGKLRD---------GTPVAVKRAKKNAFEARLS-------------------------TEFKSELSMLSRVEHMNLVRLFGYCDGKDE-
||.||||.|| ||.|          |..||||. |..    . .                          ... |. |.||  | |.|.. |||   .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RALVVEYVPNGNLREHLDVLRGTVLPFATRIDILVDVAHALTYLHYYAD-----EPIIHRDVKSSNILLTHSFR--------------
             ..| ||.|.|.|...|         .  |...  |.| .. |||          |||||| ||.|||.   ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKVADFGFSRAGPMDVDATHVSTE----------------VKGTAGYLDTEYL-----YTK-----------KLTPKSDVYSFGIVMVETMTARRPIELK
.|..|||.||   .. . .. .|                 . || ...  | |     ||.           . ..|.||||||||. | .| .|     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

RSGEERVTIRWAWKKFE--------------EGNILQILDPNLEKHPE-------IAPTMEKLAELAFRCAAPSRKERPSMQEVSQQL
            ....               .....  | | .  ...         .... ...|. .| ..  ..|||.||. ..|
-----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase RLCK4_a-2.AA IRAK 51-250 34 1.4e-52 180.99 In-house 1-219 (317) Show / Hide 
Range on Protein: 51-250
Range on HMM: 1-219/317
Sequence Identity: 34% (76 aa)

YSPSRKIGQGGFGTVYYGKLRDGT-PVAVK--RAKKNAFEARLSTEFKS---ELSMLSRVEHMNLVRLFGYCDGKDERALVVEYVPNGNLREHLDVLRG-
......||.||||.|| |...  | ..|||  .. ..  .  .  .| .   ||  ..|  | |.| | ||| . ..  || .| ||| |.  |  . | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-TV--LPFATRIDILVDVAHALTYLHYYA-DEPIIHRDVKSSNILLTHSFRAKVADFGFSRAG-PMDVDATHVS-----TEVKGTAGYLDTEYLY--TKK
 .   |.  .|..|.   | .. .||      ||||.|.||.||||   | .| .|||  | | |  .   ...       |.||. |.  |...  ...
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTPKSDVYSFGIVMVETMT
||.|.||||||||  |. |
LTKKTDVYSFGIVLLEVLT
Kinase RLCK4_a-2.AA TKL-Unique 53-254 30 2.2e-45 157.11 In-house 1-233 (290) Show / Hide 
Range on Protein: 53-254
Range on HMM: 1-233/290
Sequence Identity: 30% (71 aa)

PSRKIGQGGFGTVYYGKLRDGTPVAVKRAKK-NAFEARLSTEFKSELSMLSRVE-HMNLVRLFGYCD----GKDERALVVEYVPNGNLREHLDV------
.. |||.||.|.|| || | |.|||.|. .. . .. ... ||..|.. ... . | |.|...|||        .. .|.||.| |.|...|.       
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--LRGTVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHS-----FRAKVADFGFSRAGPMDVDATHV------STEVKGTAGYLDTEYL
   . . |... |...  |.| .. ||| .    ||||| ||||.|..       ...|..|||.|.    . . |         ....|.. ..  | |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

YT--KKLTPKSDVYSFGIVMVETMTARR------P
    .. . ||||||||||. |  |  .      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase RLCK4_a-2.AA TK 51-250 17 1.5e-38 126.32 In-house 1-389 (486) Show / Hide 
Range on Protein: 51-250
Range on HMM: 1-389/486
Sequence Identity: 17% (70 aa)

YSPSRKIGQGGFG---TVYYGKLRDG--------------------------TPVAVKRAKKN-AFEARLSTE--------------FKSELSMLS--RV
    .|.|.| ||   .|| |..|..                          ||||||  |.  | ...   .              . .|..|..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

EHMNLVRLFGYCDGKDE------------RALVVEYVPNGN----LREHLDVLRGT--------------------------------------------
.| |.|||.|.|  ...              .|.||.|.|.    ||..|   |..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------VLPFATRIDILVDVAHALTYLHYYADEPI----IHRDVKSSNILLTHSFR-----------AKVADFGFS
                               |. .... . ...| .. |||    |      .|||.   |.|.... .           .|.|||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------RAGPMDVDATHVSTEVKGTAG-------------------------YLDTEYLY---------TKKLTPKSDVYSFGIVMVETMT
      .|  .. |   .... .||..                         ..  | |          ..| |.||||.|||..| | .|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase RLCK4_a-2.AA TyrKc 51-325 24 6.2e-36 126.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 51-325
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YSPSRKIGQGGFGTVYYGKLRDGTPVAVKRAKKNAFEARLSTEFKSELSMLSRV--EHMNLVRLFGYCDGK-------DERALVVEYVPNGNLREHLDVL
 .  .|.| | ||.|| |...  ..||||  |..|       .| .|.......  .| |.|||.|.|  .       .   .|.||.|.|.|...|   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RGTVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHSFRAKVADFGFSRAGPMD------VDATHVST--EVK--GTAGYLDTEYLYTKK
|.. |. .. ... ...|    |||   . ..||||    |.|... ...|..||| ||..  |       |  ....    |       .  | . ..|
RPK-LCMKDLLSFCWQIACGMEYLH---SKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTPKSDVYSFGIVMVETMTARRPIELKRSGEER--VTIRWAWKKFEEGNILQILDPNLEKHPEI----APTMEKLAELAFRCAAPSRKERPSMQEVSQQL
 |.||||.|||..| | .|     .   .|..   .. . . .. ..|. . . . ..   | .    .|  ... ..  .| .   ..||...|. ...
FTTKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCP--DEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RLCK4_a-2.AA Pkinase 51-252 27 1.1e-35 127.25 Pfam 1-209 (293) Show / Hide 
Range on Protein: 51-252
Range on HMM: 1-209/293
Sequence Identity: 27% (59 aa)

YSPSRKIGQGGFGTVYYGKLRDG-TPVAVKRAKKNAFEARLSTEFKS--ELSMLSRVEHMNLVRLFGYCDGKDERALVVEYVPNG----NLREHLDVLRG
|   ||||.|.||.|| .. ..    ||||. ||   .     .     |.... |. | | |||....  ||.  .| ||...|     | ... . |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TVL--PFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHSFRA----KVADFGFSRAGPMDVDATHVSTEVKGTAGYLDTEYLY-TKKLTPKS
...  .  . ....  .. .| |.|      |||||.|..|||. .        |..|||...         .  | . || .|.  | .   .. .||.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGIVMVETMTAR
|..|.|... | .. |
DMWSCGCILYEMLCGR
Kinase RLCK4_a-2.AA S_TKc 51-328 21 7e-35 123.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 51-328
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

YSPSRKIGQGGFGTVYYGKLRD-GTPVAVKRAKKNAFEARLSTEFKSELSMLSRVEHMNLVRLFGYCDGKDERALVVEYVPN--GNLREHLDVLRG----
|   ||||.|.||.|| .. .. |  ||.|. |           ...|...|..  | |.|.|.....  |.  .| ||...  |.|.....  ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

TVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHSFRAKVADFGFSRAGPMDVDATHVSTEVKGTAGYLDTEYLYTKKLTP-KSDVYSFG
 ..|  .   ..  .. || |.|   .  |||||.| .||||..  . |..|||..|            | . ||  |.  | |   . .. |.|..|.|
FPFPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

IVMVETMTARRPIELKRSGEERVTIRWAWKKFEEGNILQILDPNLEKHPEIAPTMEKLAELAFRCAAPSRKERPSMQEVSQ------QLTLI
... | .. . | .     .. ....                             . . ..  .|     ..||.  |. |      .   .
CILYEMLCGYPPFP-----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RLCK4_a-2.AA UTK 51-250 25 9.4e-32 105.9 In-house 1-235 (296) Show / Hide 
Range on Protein: 51-250
Range on HMM: 1-235/296
Sequence Identity: 25% (61 aa)

YSPSRKIGQGGFGTVYYGKLRDGT------PVAVKRAKKNAFEARLST---EFKSELS---MLSRVE-HMNLVRLFGYCDGKDERALVVEYVPNGNLRE-
  ..|..||| ||.|. ..... .       |||| ... |.  . ..   .|  |     |..... |.|..|| |.|      ..|.|| .||.||  
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

----HLDVL-RGTVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHS-------FRAKVADFG---FSRAGP-------MDVDATHVSTE
    . ..  ... |   .|..  .|.|... |||      ..|||.   |.|....         .|.||||   .||. .       .. .    ...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLH---SCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH

-----VKGTAGYLDTEYLYTK-KLTPKSDVYSFGIVMVETMT
     .. .|     | |.   . | ||||.|||.|. |..|
QDRWPIRWMA----PEALTHHTRFTTKSDVWSFGVVCWEIWT
Kinase RLCK4_a-2.AA Dicty4 51-244 31 4.6e-31 100.97 In-house 1-206 (277) Show / Hide 
Range on Protein: 51-244
Range on HMM: 1-206/277
Sequence Identity: 31% (67 aa)

YSPSRKIGQGGFGTVYYGKLRDGTPVAVKRA---KKNAFEARLSTEFKSELSMLSRVEHMNLVRLFGYCD----GKDERALVVEYVPNGNLREHLDVLRG
.    .||.|.||.|| |. | |. |||| .   . |..|..| .||. | . ..   | |.. . |.|      . .   | ||.| |||   . .|. 
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENML-NEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL---YSLLHD

--------TVLPFATRID---ILVDVAHALTYLHY-YADEPIIHRDVKSSNILLTHSFRAKVADFGFSRAGPMDVDATH-VSTEVKGTAGYLDTEYLYTK
        . |.. ...    .  |.|  ...||    .  ||||| ||.|.|   ..|.||.|||.|.    . | .   .| ..||...   | .  .
KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT-ACGTPCWMAPEVMMHQ

KLTPKSDVYSFGIV
  . |.||||||||
PYNEKADVYSFGIV
Kinase RLCK4_a-2.AA Pkinase_Tyr 51-201 28 5.8e-30 102.09 Pfam 1-160 (270) Show / Hide 
Range on Protein: 51-201
Range on HMM: 1-160/270
Sequence Identity: 28% (46 aa)

YSPSRKIGQGGFGTVYYGKLR-----DGTPVAVKRAKKNAFEARL--STEFKSELSMLSRV-EHMNLVRLFGYCD-GKDE--RALVVEYVPNGNLREHLD
 .  .|.|.| ||.|| |...     ...|||||   |.    .   . .| .|.....    | |.||| | |   ..     .|.||.|.|.|...| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VL--RGTVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHSFRAKVADFGFSRA
     .  |.  . ... ...| .. ||.   . ..||||.   |.|.|... .|..||| .|.
KHREDKQPLTMKDLLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase RLCK4_a-2.AA TK-Unique 55-250 26 2.2e-29 98.57 In-house 5-234 (294) Show / Hide 
Range on Protein: 55-250
Range on HMM: 5-234/294
Sequence Identity: 26% (62 aa)

RKIGQGGFGTVYYGKLRDGT-------PVAVKRAKKNAFEARLSTEFKSELSMLSRVE-HMNLVRLFGYCDGKD-ERALVVEYVPNGNLREHLDVLRG--
..||.| ||.|. |... ..        ||||  |.|| . . . .|..|..|.. .  | |.|...|.|  .|    .. ||.|.|||. .|   |.  
DVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQ-DFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAM

----------------TVLPFATRID------ILVDVAHALTYLHY--YADEPIIHRDVKSSNILLTHSFRAKVADFGFSRAGPMDVDATHVSTE--VKG
                .  |. . |.      .....| .. ||.   .    |.|||. ..|.|||. ...|..|||..| .    .  .....   . 
RQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK---IVHRDLCARNVLLTEDKVCKICDFGMARDVYT--NGVYSMMCSQGRI

TAGYLDTEYLY--TKKL-TPKSDVYSFGIVMVETMT
   ..  |.|.  ..   |.||||.|||..| | .|
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase RLCK4_a-2.AA Dicty4-Unclassified 54-250 33 1.6e-27 91.28 In-house 4-203 (263) Show / Hide 
Range on Protein: 54-250
Range on HMM: 4-203/263
Sequence Identity: 33% (69 aa)

SRKIGQGGFGTVYYGKLRDGTPVAVKRAKKNAFEAR--LSTEFKSELSMLSRVEHMNLVRLFGYC-DG---KDERALVVEYVPNGNLREHLD---VLRGT
 . ||.| |  |. |  . |  ||||    | | .|  .  .|| |  .|  . | |||.. |||      |     | |  . ||| |  .     .  
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

VLPFAT--RIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTHSFRAKVADFGFSRAGPMDVDATHVSTEVKGTAGYLDTEYLYTKKLTPKSDVYSFG
 .       | .  |.|  . .||      .||||.||||||.   | .|.|||| ||     .| .   | . ||      | |     . ||||||..
PIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRV----IDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

IVMVETMT
... | .|
MMLYELAT
Kinase RLCK4_a-2.AA MLK 51-200 28 2.6e-27 91.85 In-house 1-181 (291) Show / Hide 
Range on Protein: 51-200
Range on HMM: 1-181/291
Sequence Identity: 28% (52 aa)

YSPSRKIGQGGFGTVYYGKLRDGTP-----VAVKRAKKNAFEARLSTE-----FKSELSMLSRVEHMN----LVRLFGYCDGKDE-RALVVEYVPNGNLR
   ...|| |.|| |. |. | ..      |||||.. ..| .  .|.     |. |   |... | |     ... | |       ..| ||...| | 
IQFHEWIGSGSFGKVWKGRWR-NKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

EHLDVLRG------------TVLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNILLTH------SFRAKVADFGFSR
. |   |.             | ...  ... ...|... |||. |  |||||| ||.|||...         .|..||| ||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
Kinase RLCK4_a-2.AA LRRK 51-201 24 8.9e-26 88.16 In-house 1-229 (351) Show / Hide 
Range on Protein: 51-201
Range on HMM: 1-229/351
Sequence Identity: 24% (56 aa)

YSPSRKIGQGGFG-TVYYGKLRD---------------------------GTPVAVKRAKK--------------------------------NAFEARL
    ..||.|||| .|| .|.|.                           ...||.|  ..                                 .. .| 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

STEFKSELSMLSRVEHMNLVRLFGYCDGKDERALVVEYVPNGNLREHLDVLRGT-------VLPFATRIDILVDVAHALTYLHYYADEPIIHRDVKSSNI
  ||  |....|. .| |.| |.|.|   . ...| ||.|.|.| ..|   . .       ...  ... | ...| .. |||  .. |||||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL-THS-----------FRAKVADFGFSR--A
|| ...             ||.|||| ||  .
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQ
Kinase RLCK4_a-2.AA IRAK 298-325 28 9.1e-05 13.02 In-house 290-317 (317) Show / Hide 
Range on Protein: 298-325
Range on HMM: 290-317/317
Sequence Identity: 28% (8 aa)

EKLAELAFRCAAPSRKERPSMQEVSQQL
.... .| .|..   ..|..| .| |||
KEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase RLCK4_a-2.AA UTK 298-325 28 0.000694 9.18 In-house 269-296 (296) Show / Hide 
Range on Protein: 298-325
Range on HMM: 269-296/296
Sequence Identity: 28% (8 aa)

EKLAELAFRCAAPSRKERPSMQEVSQQL
. . .|  || ...  |||..... ||.
HPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RLCK4_a-2.AA LRRK 235-254 42 0.001569 8.34 In-house 262-282 (351) Show / Hide 
Range on Protein: 235-254
Range on HMM: 262-282/351
Sequence Identity: 42% (9 aa)

KSDVYSFGIVMVETMTAR-RP
|.|.||||... | .| . .|
KVDCYSFGMILWELLTRQHHP
Kinase RLCK4_a-2.AA Pkinase_Tyr 229-250 54 0.004069 11.18 Pfam 188-209 (270) Show / Hide 
Range on Protein: 229-250
Range on HMM: 188-209/270
Sequence Identity: 54% (12 aa)

TKKLTPKSDVYSFGIVMVETMT
..| | ||||.|||..| | .|
YGKFTTKSDVWSFGVLMWEIFT
Kinase RLCK4_a-2.AA TK 297-325 20 0.00627 4.8 In-house 447-486 (486) Show / Hide 
Range on Protein: 297-325
Range on HMM: 447-486/486
Sequence Identity: 20% (8 aa)

M-----------EKLAELAFRCAAPSRKERPSMQEVSQQL
|           | ...|  .| ..  ..||..... .||
MRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RLCK4_a-2.AA MLK 235-254 45 0.011255 5.26 In-house 216-235 (291) Show / Hide 
Range on Protein: 235-254
Range on HMM: 216-235/291
Sequence Identity: 45% (9 aa)

KSDVYSFGIVMVETMTARRP
|.||.|.|.|. | .| . |
KCDVWSWGVVLWEMLTREVP
Kinase RLCK4_a-2.AA Dicty4-Unclassified 307-325 31 0.035259 3.22 In-house 245-263 (263) Show / Hide 
Range on Protein: 307-325
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CAAPSRKERPSMQEVSQQL
|   . . ||.| .. | |
CWHNDPNKRPTMNQIIQYL
Kinase RLCK4_a-2.AA Dicty4 313-327 35 0.041666 3.02 In-house 261-277 (277) Show / Hide 
Range on Protein: 313-327
Range on HMM: 261-277/277
Sequence Identity: 35% (6 aa)

KERPSMQEVSQQ--LTL
. |||..|..|.  |  
QHRPSFEEIIQRRILEH
Kinase RLCK4_a-2.AA MLK 313-325 38 0.069979 2.47 In-house 279-291 (291) Show / Hide 
Range on Protein: 313-325
Range on HMM: 279-291/291
Sequence Identity: 38% (5 aa)

KERPSMQEVSQQL
..|||.... |.|
HKRPSFRQIVQHL
Kinase RLCK4_a-2.AA TK-Unique 311-325 33 0.173646 1.04 In-house 280-294 (294) Show / Hide 
Range on Protein: 311-325
Range on HMM: 280-294/294
Sequence Identity: 33% (5 aa)

SRKERPSMQEVSQQL
...||||  .. ..|
EPEERPSFRQIKHRL
Kinase RLCK4_a-2.AA Pkinase_Tyr 306-325 30 4.788051 0.78 Pfam 251-270 (270) Show / Hide 
Range on Protein: 306-325
Range on HMM: 251-270/270
Sequence Identity: 30% (6 aa)

RCAAPSRKERPSMQEVSQQL
.| ..  ..||...|. .||
QCWHYDPEDRPTFSEIHEQL