Gene SD21_a (S.moellendorffii)

SD21_a

Species: S.moellendorffii
Alias: SD21_a
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD21

Sequence

Name Sequence Type Origin Length Description Download
SD21_a.AA Protein None 450 None Fasta, JSON
SD21_a.NA RNA None 1353 None Fasta, JSON
SD21_a.kin_dom Protein Kinase Domain None 268 None Fasta, JSON

Protein domain

Protein domains of SD21_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SD21_a.AA TKL 112-376 22 7.9e-64 218.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 112-376
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGTGGFGGVYEGVLPD---------GRKVAVKKLES---TGQGK-------------------------KQFYAEVAILGTIHHWNLVKLLGFCSEGLN-
.| |||| || |..           |. |||||. |       |                         ...  |. ..  ..| |.|...|.| .. . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEHMENGSLDKWIYQDCVEQKVLNWEQRMEIMLGMARGLAYLHE----ECVEK--IIHLDIKPQNILLNEDLV-----------
              .|.| ...|||   .           |.||. ..|..|||..|||      |  |  ||| |.|..|||..|..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKVADFGLSRLMSRDQSYVMTT------------------MRGTPGYLAPEWLLEA----------------AITEKSDVYSFGVVLLEVISGRRNF
   .|..|||||| ||....  .|                    .|||...||| | ..                  .||.||||||.|| |.....| .
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

SRVS-EREKFYLPAYALELVTQE-KDMELVDP-------RLKGKCDEAIVRTVIRIAFQCLQENGSSRPSMGKVVQML
.    . ..|  | . ....    | . .  |       . .  . . . . ..... .| ... ..|||. .... |
YDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHK-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SD21_a.AA Pkinase 107-304 28 2.9e-56 198.01 Pfam 2-209 (293) Show / Hide 
Range on Protein: 107-304
Range on HMM: 2-209/293
Sequence Identity: 28% (61 aa)

NFSKVLGTGGFGGVYEGVLPDGRK-VAVKKLESTGQGKKQFYA-----EVAILGTIHHWNLVKLLGFCSEGLNRLLVYEHMENG----SLDKWIYQDCVE
 . ...| |.|| ||...  . .| ||||...  .. ... ..     |..|.  ..| | |.|.... .. .  .| |..|.|    .|  .|     .
HIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--WR

QKVL--NWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNEDLVA----KVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLL-EAAITEKSD
....   ...   .|. ..|||.|.|..   .||| |.||.|||.... .     |..||||.....   ...|||  |||.|.|||...    .. |.|
HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGVVLLEVISGR
..|.|..| |...||
MWSCGCILYEMLCGR
Kinase SD21_a.AA IRAK 107-376 30 2.5e-51 176.84 In-house 2-317 (317) Show / Hide 
Range on Protein: 107-376
Range on HMM: 2-317/317
Sequence Identity: 30% (98 aa)

NFSKVLGTGGFGGVYEGVLPDGRK--VAVKKLE-----STGQGKKQFYA---EVAILGTIHHWNLVKLLGFCSEGLNRLLVYEHMENGSLDKWIYQDCVE
. . ..| |||| || |.. ..    .|||||      |... ...| .   |. .. ...| |.| |.|.|.|. .  |||. | ||||       |  
HKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL--WCQD

-QKV---LNWEQRMEIMLGMARGLAYLHEEC-VEKIIHLDIKPQNILLNEDLVAKVADFGLSRLM---S--RDQSY--VMT-TMRGTPGYLAPEWLL--E
 |     | | || .| .| |.|. .||.      ||| |||. |||| .....| .|||| |     |   .|.|   || . |||  |..|| .    
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

AAITEKSDVYSFGVVLLEVISGRRNFSRVSE-REKFYLPAYALELVTQEK-------------------------DMELVDPRLKGKCDEAIVRTVIRIA
  .| |.||||||.|||||..|.|    ... .|  ||  .  |.  ...                         ..|.   .... |... .      |
GQLTKKTDVYSFGIVLLEVLTGCRAV--YDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCA

FQCLQENGSSRPSMGKVVQML
 .|. .    |..| .|.| |
CCCGHHRANRRCDMAWVMQQL
Kinase SD21_a.AA TKL-Unique 108-303 30 4.9e-46 159.26 In-house 1-224 (290) Show / Hide 
Range on Protein: 108-303
Range on HMM: 1-224/290
Sequence Identity: 30% (70 aa)

FSKVLGTGGFGGVYEGVLPDGRKVAVKKLE----STGQGKKQFYAEVAILGTIH-HWNLVKLLGFCS----EGLNRLLVYEHMENGSLDKWIYQ------
|....|.||.| || |. . | .||.|...    |  . .. |. || .. ..| | |.|.. |.|        |. .| | .. |||.. . |      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

DCVEQKVLNWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNED-----LVAKVADFGLSRLMSRD--QSYVMT------TMRGTPGYLAPEWL
   . . ||..||. . . .|.|. ||| .    |||.|.|..|.|....     . .|..|||||.. |..   .. .       |  |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LE--AAITEKSDVYSFGVVLLEVISG
    . ..|||||||||.|| | ...
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD21_a.AA MLK 107-304 28 1.6e-44 152.36 In-house 2-233 (291) Show / Hide 
Range on Protein: 107-304
Range on HMM: 2-233/291
Sequence Identity: 28% (67 aa)

NFSKVLGTGGFGGVYEGVLPDGRK-----VAVKKLE-------STGQGKKQFYAEVAILGTIHHWN----LVKLLGFCSE-GLNRLLVYEHMENGSLDKW
.|....| |.|| |. |.   ..      ||||. .       .|.  ...|  |. .|  . | |     ....| |.. . . ..| | .|.|||   
QFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IYQDCV-------EQK---VLNWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNE------DLVAKVADFGLSRLMSRDQSYVMTTMRGTPGY
..           .||   |   .. | ..| .|||..|||.. . .||| |.|..|||. |      ....|..|||.|| ... .   |. ..||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

LAPEWL---LEAAITEKSDVYSFGVVLLEVISGR
 ||| .    .   .||.||.|.|||| |.....
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
S_TKc SD21_a.AA S_TKc 106-376 24 2.6e-42 147.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 106-376
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

DNFSKVLGTGGFGGVYEGVLPD-GRKVAVKKLESTGQGKKQFYAEVAILGTIHHWNLVKLLGFCSEGLNRLLVYEHMEN--GSLDKWIYQDCV--EQKVL
  . ...| |.|| || ..  . ||.||.|..       .... |..||   || |.|||.... .  .  .| |....  |.| . | .      ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNEDLVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEAAITE-KSDVYSFGVVLLE
.  .   .|  ....|.|.|.    .||| |.||.||||.|  . |..||||.|..        ||. ||| |.||| |     .  |.|..|.|..| |
PE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

VISGRRNFSRVSEREKFYLPAYALELVTQEKDMELVDPRLKGKCDEAIVRTVIRIAFQCLQENGSSRPSMGKVVQ---------ML
 ..|.  |.          ..  ....                      . .. .  .||| . . ||.  .. |          .
MLCGYPPFP---------QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD21_a.AA Dicty4 107-299 33 3.3e-42 138.68 In-house 2-209 (277) Show / Hide 
Range on Protein: 107-299
Range on HMM: 2-209/277
Sequence Identity: 33% (71 aa)

NFSKVLGTGGFGGVYEGVLPDGRKVAVKKLESTGQGK-----KQFYAEVAILGTIHHWNLVKLLGFCS----EGLNRLLVYEHMENGSLDKWIYQ---DC
|. . .|.|.|| || |    | .|||||| .. |.      . | .||.|.. | | |.....| |     .    . | | |  |.| . .     . 
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

VEQKVLNWEQRME---IMLGMARGLAYLHE-ECVEKIIHLDIKPQNILLNEDLVAKVADFGLSRLMSRDQ--SYVMTTMRGTPGYLAPEWLLEAAITEKS
 . . | |. .     ...  |||...||.  .|  |||.|.|. |.|  .....||.|||||..| ..   .  ..|. |||.. ||| . . . .||.
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVLLE
|||||| || |
DVYSFGIVLWE
Kinase SD21_a.AA TK 106-376 15 4.3e-42 138.42 In-house 1-486 (486) Show / Hide 
Range on Protein: 106-376
Range on HMM: 1-486/486
Sequence Identity: 15% (77 aa)

DNFSKVLGTGGFG---GVYEGVLPDGR--------------------------KVAVKKLEST-GQGKKQFYA--------------EVAILGTIH----
  . |.|| | ||    ||.| . ...                          .|||| | .. .. ...| .              |....   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HWNLVKLLGFCSEGLN------------RLLVYEHMENGS----LDKWIYQDCVEQKV-----------------------------------------
 | |.|.|.| |..| .             ..| |.|..|.    |...  .   . .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNWEQRMEIMLGMARGLAYLHEECVE---KIIHLDIKPQNILLNEDLV-----------AKVADFG---
                               |. .|.. ...  |.|..|||.  .|   ...| |.   |.|..|..|           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRLMSRDQSYVMTTMRGTPG-------------------------YLAPEWLLEAA---------ITEKSDVYSFGVVLLEVIS-GRRNFSRVS
     |.| . .|. |. .. .||..                         ..||| |..            |.||||.||||.. |. . |.  .    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

EREKFYL---PAYALELVTQ----------EKDMELVDPRLKGKCD--------EAIVRTVI-RIAFQCLQENGSSRPSMGKVVQML
  ..      ..  .|....          |    .  |. .. .|        .    ... ..  || ... . ||..  ....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SD21_a.AA Pkinase_Tyr 107-302 30 6.3e-41 139.24 Pfam 2-209 (270) Show / Hide 
Range on Protein: 107-302
Range on HMM: 2-209/270
Sequence Identity: 30% (65 aa)

NFSKVLGTGGFGGVYEGVLP-----DGRKVAVKKL--ESTGQG--KKQFYAEVAILGTI-HHWNLVKLLGFCS-EGLN--RLLVYEHMENGSLDKWIYQD
 | |.|| | || ||.|..      .. .||||.|   .. .   .. | .|..|. .. || |.|.|.| |. .|     ..| |.|..|.|..   . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

CVEQKVLNWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNEDLVAKVADFGLSRLMSRDQSY-VMTTMRGTPG-YLAPEWLLEAAITEKSDVY
. ... |. ..  .. .  |.|..||..     .|| |.   |.|..|..|.|..||||.|..  |  | ....    |   .||| . .   |.||||.
REDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SFGVVLLEVIS
||||.. |...
SFGVLMWEIFT
Kinase SD21_a.AA TyrKc 106-376 25 9e-39 136.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 106-376
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

DNFSKVLGTGGFGGVYEGVLPDGRKVAVKKLESTGQGKKQFYAEVAILGTI--HHWNLVKLLGFCSEG-------LNRLLVYEHMENGSLDKWI-YQDCV
  . |.|| | || ||.|..   ..||||.| .    .. |. |  |.  .  || |.|.|.| |...          ..| |.|..|.|.. . .    
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

EQKVLNWEQRMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNEDLVAKVADFGLSRLMSRD-------QSYVMTTMRGTPG-----YLAPEWLLEAA
    |....  ....  |.| .|||.    ..|| |.   |.|..|....|..||||||    |       . |.... .|. .      .||| . .  
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

ITEKSDVYSFGVVLLEVIS-GRRNFSRVSEREKFYLPAYALELVTQEKDMELVDPRLKGKCDEAI-----VRTVIRIAFQCLQENGSSRPSMGKVVQML
 |.||||.||||.. |. . |    . . ..  .  .. ..|.| | . |.  .  .     . .        . .|  || .|. ..||..  ... .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SD21_a.AA Dicty4-Unclassified 107-303 33 1.6e-37 126.02 In-house 2-204 (263) Show / Hide 
Range on Protein: 107-303
Range on HMM: 2-204/263
Sequence Identity: 33% (70 aa)

NFSKVLGTGGFGGVYEGVLPDGRKVAVKKLESTGQGKK-----QFYAEVAILGTIHHWNLVKLLGFCSEGLNR-------LLVYEHMENGSLDKWIY-QD
   . .| | |  |. |.   |. |||||. .            | .||.||| | | ||||. | |   .|          | | |  | |   |  . 
QIDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC---INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

CVEQKVLNWEQ--RMEIMLGMARGLAYLHEECVEKIIHLDIKPQNILLNEDLVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEAAITEKSDVY
   |. .  .    . . .  |.|...||      .|| |||  |||.  .  .|.||||.||  .  .   |||  |||   .|| |   . . |||||
SEQQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN--MTTIAGTPKWESPECLMHESYNQKSDVY

SFGVVLLEVISG
|....| | . |
SYAMMLYELATG
Kinase SD21_a.AA CAMK 111-297 16 1.8e-37 117.8 In-house 1-324 (425) Show / Hide 
Range on Protein: 111-297
Range on HMM: 1-324/425
Sequence Identity: 16% (54 aa)

VLGTGGFGGVYEGVLP-DG------------RKVAVKKLEST-----------------------------GQGKKQFYAEVAILGT-------IHHWNL
.||.|.|| |....   ..            .|||.| .. .                             .. .|... |..|. .       ..| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLGFCSEGLN-------------------RLLVY---EHMENG----SLDKWIYQD------------CVEQKVLNWEQRMEIMLGMARGLAYLHEEC
.||. .   . .                     .|    |....|     |  .| .             . | . .. ..   ..  .. ...|.|.  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS--

VEKIIHLDIKPQNILLNED-----------------LVAKVADFGLSRLMSRDQSYV----------------------MTTMRGTPGYLA-PEWLL---
  .|.|.|.|| ||||...                    |..|||... . .....                       |.|. |||.| | ||.|.   
-HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------EAAITEKSDVYSFGVVL
           .  ...|.|. | ||.|
HCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase SD21_a.AA Ciliate-E2 106-305 21 8.1e-35 116.94 In-house 1-294 (365) Show / Hide 
Range on Protein: 106-305
Range on HMM: 1-294/365
Sequence Identity: 21% (65 aa)

DNFSKVLGTGGFGGVYEG-VLPDGRKVA---------------------VKKLESTGQGKKQFYAEVAILGTIH----------------HWNLVKLLGF
 .| |..|.|.|| ||.. |  .....|                     . .     ....|.  |  |. .|.                | |..|.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CS--EGLNRLLVYEHMENGSLDKWIYQDCVEQ-------KVLNWEQRMEIMLGMAR---------------GLAYLHEECVEKIIHLDIKPQNILLNEDL
       |  || |  . |.| ..|.. .  .       | ...... .||   ..               .| |||..   .||| ||||.|||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN--NIIHRDIKPENILF----

VAKVADFGLSR----------------LMSRDQSYVMTTMR---------------GTPGYLAPEWLLEAA---------ITEKSDVYSFGVVLLEVISG
  |..|||||.                ..   ...  .| .               |||||.||| |              ..|.|..|.||.| | ..|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

RR
..
KP
Kinase SD21_a.AA LRRK 107-307 23 2e-32 112.01 In-house 2-283 (351) Show / Hide 
Range on Protein: 107-307
Range on HMM: 2-283/351
Sequence Identity: 23% (69 aa)

NFSKVLGTGGFG-GVYEGVLPD---------------------------GRKVAVKKLEST-------------------------------GQGKKQFY
 . . .| ||||  || . . .                           . .||.||.. .                               ....   .
KIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAF

A----EVAILGTIHHWNLVKLLGFCSEGLNRLLVYEHMENGSLDKWIYQDCVEQK------VLNWEQRMEIMLGMARGLAYLHEECVEK--IIHLDIKPQ
     ||.|. . .| |.|.|.||| . |   .| | . .|.|.. . ..  . .      ...|  . .|.|  |.|..|||     .  ||| | |. 
REFRHEVWIMSHLNHPNIVSLKGFCIHPL--CMVMEYAPHGDLYHFL-HNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSP

NILL---N---------EDLVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEA---AITEKSDVYSFGVVLLEVISGR-RNF
||||   .         .. .||.||||.||. . ... |  .. |.||..||| . .      |||.|.||||..| | .... . |
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPF
Kinase SD21_a.AA MLK 357-376 40 0.000709 9.48 In-house 272-291 (291) Show / Hide 
Range on Protein: 357-376
Range on HMM: 272-291/291
Sequence Identity: 40% (8 aa)

QCLQENGSSRPSMGKVVQML
|| ... ..|||.  .|| |
QCWNQDPHKRPSFRQIVQHL
Kinase SD21_a.AA Dicty4 358-378 30 0.016287 4.4 In-house 255-277 (277) Show / Hide 
Range on Protein: 358-378
Range on HMM: 255-277/277
Sequence Identity: 30% (7 aa)

CLQENGSSRPSMGKVVQM--LEG
|. .. ..|||.  ..|   || 
CWDHDPQHRPSFEEIIQRRILEH
Kinase SD21_a.AA Dicty4-Unclassified 358-376 31 0.020753 4.02 In-house 245-263 (263) Show / Hide 
Range on Protein: 358-376
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CLQENGSSRPSMGKVVQML
|. .    ||.| ...| |
CWHNDPNKRPTMNQIIQYL
Kinase SD21_a.AA LRRK 357-378 27 0.034822 3.51 In-house 330-351 (351) Show / Hide 
Range on Protein: 357-378
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

QCLQENGSSRPSMGKVVQMLEG
.| |..  .||.. ..|. |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase SD21_a.AA Pkinase_Tyr 357-376 25 2.779595 1.58 Pfam 251-270 (270) Show / Hide 
Range on Protein: 357-376
Range on HMM: 251-270/270
Sequence Identity: 25% (5 aa)

QCLQENGSSRPSMGKVVQML
|| ... . ||..  ....|
QCWHYDPEDRPTFSEIHEQL