Gene SD21_n (S.moellendorffii)

SD21_n

Species: S.moellendorffii
Alias: SD21_n
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD21

Sequence

Name Sequence Type Origin Length Description Download
SD21_n.AA Protein None 823 None Fasta, JSON
SD21_n.NA RNA None 2472 None Fasta, JSON
SD21_n.kin_dom Protein Kinase Domain None 209 None Fasta, JSON

Protein domain

Protein domains of SD21_n.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin SD21_n.AA B_lectin 77-178 35 1.3e-35 123.99 Pfam 1-137 (137) Show / Hide 
Range on Protein: 77-178
Range on HMM: 1-137/137
Sequence Identity: 35% (48 aa)

INQIVWTANRN---VPV-----SQADNLIFQD-DGNVILFGPR-G---LPVWST--GTN-GTDAQ--TLRLLDSGNLVVQ-DSR--NRTLWES--FAHPT
   .||.|||.    ||     ...  |..|. ||| .|. .  |    |||||  .|. .. |   .....||||||.  |..  |..||.|  | |||
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DVIVVGQKLQR------GMK----LTSKRSTT--DFS
| . .|.|| .      .|.    ||| .|.|  |.|
DTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin SD21_n.AA B_lectin 39-152 27 9.5e-21 76.17 SMART 1-126 (126) Show / Hide 
Range on Protein: 39-152
Range on HMM: 1-126/126
Sequence Identity: 27% (35 aa)

HWVDNQGQFMQSASGNF-ILTFFYSSRNQYYLSVVLGAAIN---QIVWTA--NRNVPVSQ---ADNLIFQDDGNVILFGPRGLPVWSTGTN-GTDAQTLR
  . ..||.  | .. | .   |..  .| ..... .   |   ..|| |  ||..||.       | .|.||| ...   . ||||..|. ..   ...
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQWCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNGNYVAV

LLDSGNLVVQDSR----NRTLWESFAHP
|.|.||.|. |.     ....|.|| ||
LQDDGNFVIYDPDDNDSGNFIWQSFDHP
PAN_AP SD21_n.AA PAN_AP 336-413 19 0.000326 19.89 SMART 1-85 (85) Show / Hide 
Range on Protein: 336-413
Range on HMM: 1-85/85
Sequence Identity: 19% (17 aa)

PQDFQFQDLDTNLFYFANQ--FATPASAVTLQDCKRLCTENCSCTTGFFNTTSGSCYLSN-TVKLGSFD-------STNGGFQTFIKA
..|..|  ..     |. .  .     ...|..|...| .||||.   ..  ...|.|.. . .||. .         |.|.  ..| 
CCDDCFVRMPNMKL-FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase SD21_n.AA TKL 493-769 21 1.2e-56 194.53 In-house 1-364 (364) Show / Hide 
Range on Protein: 493-769
Range on HMM: 1-364/364
Sequence Identity: 21% (84 aa)

LGGGGFGSVYEGTLPD---------KSKVAVKQLES---IGQGK-------------------------KEFRAEVATIGSIHHVNLVRLRGFCSEGTH-
.| |||| || |..              ||||.. |       |                         .... |.  . ...| |.|.. |.| .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLARGSLDKSLFNESSSQLLSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHE----DCRER--IIHCDIKPENILLDEHF
              .|.|.  .|||   |                       |. | ..||..|||. |||      |.    |||.|.|..|||.||..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENW

T--------------AKVSDFGLAKLMNREQSHVFTT------------------MRGTRGYLAPEWLLNT----------------AISEKSDVYSFGM
|              .|..||||.. |.....   |                    .|| ...||| | ..                  |||.||||||.
TNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

VLLEIVSGRKNFDPNETSDKWYIPAYAF---KQAEVGALVELLDARLKGHSNE-------EQV-VKAVKIALWCIQEEMHLRPSIGKVVQML
|| ||.....       .| .|.| ...   ..  ... .. |   .. . ..       ...     |.. .| ... . |||  .... |
VLWEILTRCR-----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SD21_n.AA Pkinase 489-697 27 4e-48 171.0 Pfam 3-209 (293) Show / Hide 
Range on Protein: 489-697
Range on HMM: 3-209/293
Sequence Identity: 27% (63 aa)

FSKKLGGGGFGSVYEGTLPDKSK-VAVKQLESIGQGKKEFRA-----EVATIGSIHHVNLVRLRGFCSEGTHRLLVYEFLARG----SLD----KSLFNE
. .|.| |.||.||...  . .| ||||...  .. ... ..     |..   ...| | |||.... ...|  .| |..  |    .|           
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-----

SSSQLLSDSPVNQQPPVVL--DWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTA----KVSDFGLAKLM-NREQSHVFTTMRGTRGYL
             .   ..  ....  .... ..||| |.|.    .|||.|.||||||.|.. .     |..||||||.. .  .|  .||  ||..|.
-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYM

APEWLL-NTAISEKSDVYSFGMVLLEIVSGR
|||... .. .. |.|..|.| .| | ..||
APEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase SD21_n.AA TKL-Unique 489-696 31 3.5e-46 159.75 In-house 1-224 (290) Show / Hide 
Range on Protein: 489-696
Range on HMM: 1-224/290
Sequence Identity: 31% (73 aa)

FSKKLGGGGFGSVYEGTLPDKSKVAVKQLE----SIGQGKKEFRAEVATIGSIH-HVNLVRLRGFCS----EGTHRLLVYEFLARGSLDKSLFNESSSQL
|..|.|.||.|.|| |. . ...||.||..    |  . ..||. || ..  .| | |.|.. |.|        .. .| |.. .|||..         .
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYD---------V

LSDSPVNQ---QPPVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEH-----FTAKVSDFGLAKLMNREQSHVFT--------TMRGT
|...  |     .   |..  |...|.  |.|. |||      |||.|.|. |.|.|..     . .|..||||.|. ...    ..        |  |.
LHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGS

RGYLAPEWLLN--TAISEKSDVYSFGMVLLEIVSG
  ..||| | .  . .||||||||||.|| ||...
FRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD21_n.AA Dicty4 489-694 35 5.7e-45 148.02 In-house 3-211 (277) Show / Hide 
Range on Protein: 489-694
Range on HMM: 3-211/277
Sequence Identity: 35% (78 aa)

FSKKLGGGGFGSVYEGTLPDKSKVAVKQLESIGQGK-----KEFRAEVATIGSIHHVNLVRLRGFCS----EGTHRLLVYEFLARGSLDKSLFNESSSQL
. ...|.|.||.|| ||   | .|||| | .  |.      .|||.||.  ..| | |.. . | |     .    . | |.. .|.| .         |
IEQRIGKGSFGEVYKGTWRGK-EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYS---------L

LSDSPVNQQPPVVLDWDTRYN---IALGTARGLVYLHE-DCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVF--TTMRGTRGYLAPEWLL
| | |  ||. . ||| ..     .|. .|||. .||. ..  .||| |.|. |.| |.....||.||||...| .. .| .  .|. || .. ||| . 
LHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM

NTAISEKSDVYSFGMVLLEIV
. .  ||.||||||.|| ||.
HQPYNEKADVYSFGIVLWEIL
Kinase SD21_n.AA LRRK 487-701 23 1.2e-38 134.36 In-house 1-284 (351) Show / Hide 
Range on Protein: 487-701
Range on HMM: 1-284/351
Sequence Identity: 23% (70 aa)

NGFSKKLGGGGFG-SVYEGTLPD---------------------------KSKVAVKQLESIG-----------------------------------QG
  . ...| |||| .|| ... .                            ..||.|... ..                                     
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

KKEFRAEVATIGSIHHVNLVRLRGFCSEGTHRLLVYEFLARGSLDKSLFNESSSQLLSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRER--II
  ||| ||. . . .| |.| | ||| .  .. .| |..  |.|.. |.|...... .  .       ...| ... |||  |.|. |||   . .  ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGF-HFMK------AHISWMLKLKIALQIAKGMEYLH---SHNPPII

HCDIKPENILL---D---------EHFTAKVSDFGLAKLMNREQSHVFTTMRGTRGYLAPEWLLNT---AISEKSDVYSFGMVLLEIVSGR-KNFD
|.| |..||||   .         .| .||..|||.  .    .. |. .. |. |..||| . ..     .||.|.|||||.| |.....   ||
HRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase SD21_n.AA MLK 487-697 29 6.7e-37 125.58 In-house 1-233 (291) Show / Hide 
Range on Protein: 487-697
Range on HMM: 1-233/291
Sequence Identity: 29% (69 aa)

NGFSKKLGGGGFGSVYEGTLPDKS----KVAVKQLE----SIGQG---KKEFRAEVATIGSIHHVN----LVRLRGFCSEGTH-RLLVYEFLARGSLDKS
  |....| |.||.|. |.   |      ||||. .    ....    ...|. |.     . | |     ....| |.. ..  ..| |... |||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LFNESSSQLLSDSPVNQQP-PVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDE------HFTAKVSDFGLAKLMNREQSHVFTTMRGT
| ...|    .    ..|.  .| | |   |.||  |||. |||.. .  ||| |.|. |||.||      | |.|..|||... ... .    . ..||
LHGARSKWMDAN---HNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGT

RGYLAPEWL---LNTAISEKSDVYSFGMVLLEIVSGR
  . ||| .    ..  |||.||.|.|.|| |.....
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase SD21_n.AA Pkinase_Tyr 489-698 28 8.7e-35 118.44 Pfam 3-213 (270) Show / Hide 
Range on Protein: 489-698
Range on HMM: 3-213/270
Sequence Identity: 28% (65 aa)

FSKKLGGGGFGSVYEGTLP-----DKSKVAVKQL--ESIGQG--KKEFRAEVATIGSI-HHVNLVRLRGFCS-EGTH--RLLVYEFLARGSLDKSLFNES
| |||| | ||.||.||.      .| .|||| |   .  .   ...| .|...  .. || |.||| | |. .| .   ..| |. . |.|.. | . .
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

SSQLLSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVFTTMRGTRG---YLAPEWL
             ..  |.  .  ....  |.|. ||..     .|| |.   |.|..| ...|..|||||...  .    ...  |..     .||| .
------------EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECI

LNTAISEKSDVYSFGMVLLEIVS-GRK
 .   ..||||.||| .. ||.. |..
NYGKFTTKSDVWSFGVLMWEIFTYGEQ
Kinase SD21_n.AA RIPK 493-706 24 3.4e-34 113.92 In-house 1-234 (290) Show / Hide 
Range on Protein: 493-706
Range on HMM: 1-234/290
Sequence Identity: 24% (62 aa)

LGGGGFGSVYEGTLPDKSKVAVKQLES--------IGQGKKEFRAEVATIGSIHHVNLVRLRGFCSEG-----TH-RLLVYEFLARGSLDKSLFNESSSQ
.|||||| |.  .  .   ...|              | ...   |..   .. . . |.. ||| .           .| |. . ||| . |  ...  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPY-

LLSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRE-RIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVFT-------------TMR-GT
        |..|. ..   |  .   ...|  |||  .    ||| | ||||||.| .| .|..|||||.  ....||...               | ||
--------QHHPDPWPLRCR--MIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLAT--WMMWSHSHQDRCNQREVYSMKSKNRWGT

RGYLAPEWLL--NTAI----SEKSDVYSFGMVLLEIVSGRKNFDPNETS
  |..|| ..  | .     ..|.|||||..|. |. .... . . ...
LSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCM
Kinase SD21_n.AA IRAK 586-698 41 6.7e-34 117.58 In-house 99-222 (317) Show / Hide 
Range on Protein: 586-698
Range on HMM: 99-222/317
Sequence Identity: 41% (51 aa)

NQQPPVVLDWDTRYNIALGTARGLVYLHEDC-RERIIHCDIKPENILLDEHFTAKVSDFGLAKLM----NREQSHV----FTTMRGTRGYLAPEWLL--N
.| ||  | | .|  |..|||.|. .||..     ||| |||. |||||.|||.| .||||.       ..|.. .      . |||  |..|| .    
GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

TAISEKSDVYSFGMVLLEIVSGRK
  .. |.|||||| ||||...|..
GQLTKKTDVYSFGIVLLEVLTGCR
Kinase SD21_n.AA TK 489-769 15 1.2e-32 106.13 In-house 3-486 (486) Show / Hide 
Range on Protein: 489-769
Range on HMM: 3-486/486
Sequence Identity: 15% (75 aa)

FSKKLGGGGFG---SVYEGTLPDKS--------------------------KVAVKQLESI-GQGKKEFRA--------------EVATIGSIH-----H
. |||| | ||    ||.|.. ...                          .||||.| .  .. ..||..              |.. .   .     |
LGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHH

VNLVRLRGFCSEG------------THRLLVYEFLARGS----LDKSLF-NESSSQLLSDSPVNQQPPVV------------------------------
 |.||| | |..|             . ..| |. . |.    |.. |  .    |  .|.| ||.....                              
PNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDD

-----------------------------LDWDTRYNIALGTARGLVYLHED----CRERIIHCDIKPENILLDEHFT-----------AKVSDFG----
                             |.  ..  ...  |.|. |||.        ...| |.   |.|..|. .           .|..|||    
DLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LAKLMNREQSHVFTTMRGTRG-------------------------YLAPEWLL---------NTAISEKSDVYSFGMVLLEIVS-GRKNFDPNET
    ||. .....  . .. .||..                         ..||| |.         .   ..||||.||| .. ||.. |.. . .. .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

SDKWYI---PAYAFKQAEV-------GALVE-----LLDARLKGHSN--------EEQVVKAVKI-ALWCIQEEMHLRPSIGKVVQML
...  .   ..  ... .        | | .     .  .. .. .         ..   ... .  . | ...   ||.   ....|
NQDVWKDGDNQEVMEYLRRGGRLCRSG-L-NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SD21_n.AA Dicty4-Unclassified 489-696 33 2.3e-32 108.12 In-house 3-204 (263) Show / Hide 
Range on Protein: 489-696
Range on HMM: 3-204/263
Sequence Identity: 33% (72 aa)

FSKKLGGGGFGSVYEGTLPDKSKVAVKQLESIGQGKK-----EFRAEVATIGSIHHVNLVRLRGFCSEG-THR---LLVYEFLARGSLDKSLFNESSSQL
  . .| | |  |. |    |  |||| . .           .|..||.  ||| | |||...| |     |.     | ||. .| |           .
IDQFIGKGHFSKVHKGNWKGK-DVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL---------FEV

LSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVFTTMRGTRGYLAPEWLLNTAISE
    |  || |. ||      .|.  |.|. .||   |. .|| |||  |||.| || .|. |||..      .    ||  ||    .|| |   .   
IHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN--MTTIAGTPKWESPECLMHESYNQ

KSDVYSFGMVLLEIVSG
||||||..|.| | . |
KSDVYSYAMMLYELATG
Kinase SD21_n.AA S_TKc 487-769 23 1.3e-28 102.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 487-769
Range on HMM: 1-231/231
Sequence Identity: 23% (70 aa)

NGFSKKLGGGGFGSVYEGTLPD-KSKVAVKQLESIGQGKKEFRAEVATIGSIHHVNLVRLRGFCSEGTHRLLVYEFLAR--GSLDKSLFNESSSQLLSDS
  . .|.| |.||.|| ..  . . .||.|..       . .| |..   . || |.|.| ... . .|  .| |..    |.|          ... . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL---------FDYIKKR

PVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVFTTMRGTRGYLAPEWLLNTAISE-KSD
. .  . .    ..|. ..  ....| |.|.    .|||.|.|||||||||  . |..|||||...        ||. ||. |.||| |     .  |.|
GRHGLRFPFPE-HARF-YMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCD

VYSFGMVLLEIVSGRKNFDPNETSDKWYIPAYAFKQAEVGALVELLDARLKGHSNEEQVVKAVKIALWCIQEEMHLRPSIGKVVQ---------ML
..|.| .| | ..|.  |.          ..  ||.                         |  .   | | .   ||.. .. |          .
WWSCGCILYEMLCGYPPFP---------QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD21_n.AA DRK 494-694 34 1.3e-28 94.06 In-house 8-196 (258) Show / Hide 
Range on Protein: 494-694
Range on HMM: 8-196/258
Sequence Identity: 34% (72 aa)

GGGGFGSVYEGTLPDKSKVAVKQLESIGQG----KKEFRAEVATIGSIHHVNLVRLRGFCSEGTHRLLVYEFLARGSLDKSLFNESSSQLLSDSPVNQQP
| |..| |. ||    ..|||| |           .||. |.  .    | | .   | | .    . . |.. |||| . | .||              
GRGNYGEVFRGTWRG-TQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDES--------------

PVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNREQSHVFT-TMRGTRGYLAPEWLLNTAISEKSDVYSFGM
 . .||  .  ...  |.|. |||  |   ||| | |  | | |||.  ||.||||.    . ..| |. || || .  ||| | |    || |||||. 
-IEMDWPLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAI

VLLEIV
|| |.|
VLWECV
Kinase SD21_n.AA TyrKc 489-769 23 9.1e-26 92.85 SMART 3-280 (280) Show / Hide 
Range on Protein: 489-769
Range on HMM: 3-280/280
Sequence Identity: 23% (73 aa)

FSKKLGGGGFGSVYEGTLPDKSKVAVKQLESIGQGKKEFRAEVATIGSI--HHVNLVRLRGFCSEG-------THRLLVYEFLARGSLDKSL-FNESSSQ
. |||| | || ||.||.    .|||| | .    ...|. |     ..  || |.||| | |...          ..| |. . |.|.. |  ..    
LGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

LLSDSPVNQQPPVVLDWDTRYNIALGTARGLVYLHEDCRERIIHCDIKPENILLDEHFTAKVSDFGLAKLMNRE----QSHVFTTMR---GTRG-----Y
              | ...  ....  |.|  |||.    ..|| |.   |.|..| .|.|.|||||..    .     |.   ...   |...      
--------------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

LAPEWLLNTAISEKSDVYSFGMVLLEIVSGRKNFDPNETSDKWYIPAYAFKQAEVGALVELLDARLKGHSNEE-----QVVKAVKIALWCIQEEMHLRPS
.||| .     ..||||.||| .. || .  .   |...           . .|| ..|.  . . . .....        .  .| ..| .|. . ||.
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT

IGKVVQML
   ... .
FSEIHECF
Kinase SD21_n.AA IRAK 489-567 33 4e-13 42.99 In-house 1-90 (317) Show / Hide 
Range on Protein: 489-567
Range on HMM: 1-90/317
Sequence Identity: 33% (30 aa)

FSK--KLGGGGFGSVYEGTLPDKS-KVAVKQLE-----SIGQGKKEFRA---EVATIGSIHHVNLVRLRGFCSEGTHRLLVYEFLARGSL
|.|  ..| |||| || | .  .   .||| |      |... ...|..   |. .  ...| |.| | |.|.|.    |||.... |||
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSL
Kinase SD21_n.AA Dicty4-Unclassified 750-769 30 0.071635 2.15 In-house 244-263 (263) Show / Hide 
Range on Protein: 750-769
Range on HMM: 244-263/263
Sequence Identity: 30% (6 aa)

WCIQEEMHLRPSIGKVVQML
||  ..   ||.. ...| |
WCWHNDPNKRPTMNQIIQYL