Gene SD21_m (S.moellendorffii)
SD21_m
Species: S.moellendorffii
Alias: SD21_m
External Links:
Annotation:
Sequence
Protein domains of SD21_m.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | SD21_m.AA | TKL | 36-305 | 21 | 4.2e-65 | 222.6 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 36-305
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)
LGNGGFGQVYEGFLKD---------GSRVAVKVLKEWSTQGE---------------------------KEFKAEVISMAGIHHKNVIPFKGYCTSRR--
.| ||||.|| | .. | ||||..|. . . . .... |. .| ..| |...|.|||.. .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-------------ILVYEFMVNGSLDKWLFAEPGKERLLDWPKRYEIAVGMARGLTYLHEECT-----QQIIHLDIKPENILLDENFS------------
.|.|.. .||| | |..| .| ..|||. ||| . . .||| |.|..|||.|||.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD
--PKVTDFGLSKLVDRDKA------------------RVVTNMRGTPGYLAPEWLNSNA---------------PVSTKVDVYSFGIVLLELICGRESFQ
.|..|||||. ..... . .|||...||| |. . . |.|.||||||||| |......
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---
ISSSKSSEEWY-LPPWASK------LVAEGRGLELVDTHLNEEVEY----FYQDQA-NRAIQTALCCIQQDPSNRPSMSRVLQML
.| .|. . . ....... . .. .. ... . .. . .| ..||..|||....|. |
--------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Pkinase | SD21_m.AA | Pkinase | 30-305 | 23 | 1.3e-52 | 185.89 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 30-305 Range on HMM: 1-293/293 Sequence Identity: 23% (76 aa) KNFSTKLGNGGFGQVYEGFLKDGSR-VAVKVLKEWSTQGEKEFKA-----EVISMAGIHHKNVIPFKGYCT--SRRILVYEFMVNG----SLDKWLFAEP . |.| |.||.||.. |. .. ||||..| .. ... .. |. |. ..|.|.. ...... .. .| |.. .| .| .. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-- GKERLL--DWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDENFSP----KVTDFGLSKLVDRDKARVVTNMRGTPGYLAPEWLNSNAPVSTK ... . .. .. ..||| |.|.. ||| |.||||||.|.| . |..||||.|..| . . | |||.|.|||..... . ..| WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK VDVYSFGIVLLELICGRESFQISSSKSSEEWYLPPWASK----------LVAEGRGLELVDTHLNE-EVEYFYQDQA-----------NRAIQTALCCIQ ||..|.|..| |..||| ||. .. .... .| .| .. .. ||. .. ... .|.. VDMWSCGCILYEMLCGR----------------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLC QDPSNRPSMSRVLQM--L .||. ||. .|| . KDPKKRPTAEQILQHPWF |
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| Kinase | SD21_m.AA | IRAK | 31-228 | 37 | 3.2e-51 | 176.5 | In-house | 2-221 (317) | Show / Hide |
Range on Protein: 31-228 Range on HMM: 2-221/317 Sequence Identity: 37% (82 aa) NFSTKLGNGGFGQVYEGFLKDGS-RVAVKVLKEWS----TQGEKEFKA---EVISMAGIHHKNVIPFKGYCTSRRI--LVYEFMVNGSLDKWLFAEPGKE . . ..| |||| || | .| .||| ||| .. ...| . |. ... ..|.|. |. |||| | |||..| |||| | . | HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC RL--LDWPKRYEIAVGMARGLTYLHEEC-TQQIIHLDIKPENILLDENFSPKVTDFGLSKLV----DRDKARV----VTNMRGTPGYLAPEWLN-SNAPV . | |..| .|. | |.|. .||. ||| |||. |||||..| || .|||| .. |. . . ||| |..|| .. PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL STKVDVYSFGIVLLELICGR ..|.|||||||||||.. |. TKKTDVYSFGIVLLEVLTGC |
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| Kinase | SD21_m.AA | TKL-Unique | 32-225 | 33 | 3.6e-46 | 159.72 | In-house | 1-222 (290) | Show / Hide |
Range on Protein: 32-225 Range on HMM: 1-222/290 Sequence Identity: 33% (74 aa) FSTKLGNGGFGQVYEGFLKDGSRVAVKVLKE---WSTQGEKEFKAEVISMAGIH-HKNVIPFKGYCT------SRRILVYEFMVNGSLDKWLF------A |. |.| ||.|||| | . |. ||.|.... | . ..||. || | .| |.|. . |||. .....| |.. |||.. | FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN EPGKERLLDWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDEN-----FSPKVTDFGLSKLVDRDKARVVTNM--------RGTPGYLAPEWL .. |.. .|. .| .|.|. ||| . . |||.|.|. |.|.|.| .. |. ||||||. ... . ... |.. ..||| | NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL NSN-APVSTKVDVYSFGIVLLELI ..| . |.|.||||||||| |.. RMNFCQYSEKSDVYSFGIVLWEIA |
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| Kinase | SD21_m.AA | Dicty4 | 31-235 | 35 | 3.3e-42 | 138.66 | In-house | 2-223 (277) | Show / Hide |
Range on Protein: 31-235 Range on HMM: 2-223/277 Sequence Identity: 35% (80 aa) NFSTKLGNGGFGQVYEGFLKDGSRVAVKVL---KEWSTQGE-KEFKAEVISMAGIHHKNVIPFKGYCT------SRRILVYEFMVNGSLDKWLFA---EP |. ..| |.||.|| | . |. ||||.| .. . . . .||..|| |. | | |.. |.|.|| .. | |.| |.| . | . | NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ GKERLLDWPKRYE---IAVGMARGLTYLHEECTQQIIHLDIKPENILLDENFSPKVTDFGLSKLVDRDKARVV--TNMRGTPGYLAPEWLNSNAPVSTKV .. |||| . .| |||...||. |. |||.|.|. |.| |.|. ||.|||||.. ... . . |||.. ||| . .. | |. QQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ-PYNEKA DVYSFGIVLLELICGRESFQ--ISS ||||||||| |. . | .| ... DVYSFGIVLWEILTRQEPYQKHHMP |
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| S_TKc | SD21_m.AA | S_TKc | 30-309 | 23 | 3.5e-42 | 147.37 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 30-309 Range on HMM: 1-231/231 Sequence Identity: 23% (70 aa) KNFSTKLGNGGFGQVYEGFLKD-GSRVAVKVLKEWSTQGEKEFKAEVISMAGIHHKNVIPFKGYCT-SRRILVYEFMVN--GSLDKWLFAEPG--KERLL . |.| |.||.|| . |. | .||.|..| . .. |. . ||.|.. ..... .. .| |.. . |.| . . .. . . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF DWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDENFSPKVTDFGLSKLVDRDKARVVTNMRGTPGYLAPEWLNSNAPVST-KVDVYSFGIVLL . .. ....| |.|. ..||| |.||||||||| |..||||.... | . ||| |.||| | . .. |.|..|.|..| PE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY ELICGRESFQISSSKSSEEWYLPPWASKLVAEGRGLELVDTHLNEEVEYFYQDQANRAIQTALCCIQQDPSNRPSMSRVLQ-----MLEGVI |..||. |. . |.. |.. | | ||..||. .|| .. . EMLCGYPPFP-----------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | SD21_m.AA | TK | 30-305 | 16 | 2.2e-39 | 129.2 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 30-305
Range on HMM: 1-486/486
Sequence Identity: 16% (83 aa)
KNFSTKLGNGGFG---QVYEGFLKDGS--------------------------RVAVKVLKEWSTQGEKEFKA----------------EVISMAG---I
. ||| | || .||.| ..... .||||.||| ... ..||.. |...|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
HHKNVIPFKGYCTSR--------------RILVYEFMVNGS----LDKWLFAEPGKERL-----------------------------------------
||.|.. . |.|| ..| |.| .|. |...| . ..|..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LDWPKRYEIAVGMARGLTYLHEE----CTQQIIHLDIKPENILLDENFS-----------PKVTDFG--
|. . . ... |.|. |||. |...| |. |.|..|| |..|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
------LSKLVDRDKARVVTNMRGTPG-------------------------YLAPEWLNSNAP--------VSTKVDVYSFGIVLLELIC-GRESFQ--
|.. ...|. .... .||.. ..||| ||.. . .|| ||.|||... |. |.| .
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG
ISS-----SKSSEEWYLPPWASKLVAEGRGLELVDTHLNE----------EVEYFYQ----DQAN--------------RAIQT-ALCCIQQDPSNRPSM
.|. . | ... | .| . ||.| .. ... ... ..| . ||. ||..
MSNQDVWKD------------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTF
SRVLQML
| ....|
SQLHEQL
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| Kinase | SD21_m.AA | MLK | 30-229 | 26 | 1.3e-37 | 128.04 | In-house | 1-234 (291) | Show / Hide |
Range on Protein: 30-229 Range on HMM: 1-234/291 Sequence Identity: 26% (63 aa) KNFSTKLGNGGFGQVYEGFLKDGSR-----VAVKVLK---EWSTQGE----KEFKAEVISMAGIHHKN----VIPFKGYCTSR---RILVYEFMVNGSLD .|....|.|.||.|. | . . . |||| . . . . . ..|. |. . . |.| .|.|.| |.. .| |.. .||| IQFHEWIGSGSFGKVWKGRWR-NKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY KWLFAEPGKER----------LLDWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDE------NFSPKVTDFGLSKLVDRDKARVVTNMRGTP | ....|. | .|. .|||. |||.. ..||| |.|. |||.|| . |..|||.|. . . . ....||. NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY GYLAPEWL--NSNAPVSTKVDVYSFGIVLLELICGRE . ||| . . ..| |.||.|.|.|| |.. ... AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV |
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| Kinase | SD21_m.AA | CAMK | 35-228 | 16 | 1.4e-35 | 111.63 | In-house | 1-331 (425) | Show / Hide |
Range on Protein: 35-228
Range on HMM: 1-331/425
Sequence Identity: 16% (56 aa)
KLGNGGFGQVYEGFLK-DG------------SRVAVKVLK---------------------------EW-STQGEKEFKAEVISMAG-------IHHKNV
.|| |.||.|.... | .. .||.|... .| . . .|... |. | ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IPFKGYCTS---------------------RRILVY---EFMVNG----SLDKWLFAEPGKE-----------RLLDWPKRYEIAVGMARGLTYLHEECT
| . . . . ..| |.. .| | .. . ... . .. . .. .. |.|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS---
QQIIHLDIKPENILLDEN-----------------FSPKVTDFGLSKLVDRDK----------------------ARVVTNMRGTPGYLA-PEWLNS---
. |.|.|.||||||||.| . |..|||... .|... . . |||.| | ||.||.
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH
----------NAPVSTKVDVYSFGIVLLELICGR
. ... |.|. | |..| . ||.
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY
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| Kinase | SD21_m.AA | STE | 30-228 | 21 | 6.6e-34 | 117.15 | In-house | 1-265 (359) | Show / Hide |
Range on Protein: 30-228
Range on HMM: 1-265/359
Sequence Identity: 21% (61 aa)
KNFSTKLGNGGFGQVYEGFLKD----------------GSRVAVKVLK----------------EWSTQGEK-EFKAEVISMAGIH--HKNVIPFKGYCT
. |.|.|.||.|| . .. | ..|.|... |.. . |. ... |. | . |.|.. . |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
---------SRRILVYEFMVNGSLDKWLFA--EPGK-------------ERLLDWPKRYEIAVGMARG-LTYLHEECTQQIIHLDIKPENILLDENFSPK
. .. |.| .||||. . ..|| | .. . |.. .| | |||. ||| |||| |||| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY-----ICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VK
VTDFGLSKLVDRDKA---------------RVVTNMRGTPGYLAPEWLNS-----NAPVSTKVDVYSFGIVLLELICGR
.|||... .. . | . . ||| . ||| .. . . .||.|..|.|....|...|.
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
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| Kinase | SD21_m.AA | RIPK | 36-231 | 28 | 9.7e-34 | 112.34 | In-house | 1-228 (290) | Show / Hide |
Range on Protein: 36-231 Range on HMM: 1-228/290 Sequence Identity: 28% (68 aa) LGNGGFGQVYEGFLKD-GSRVAVKVLKEWS------TQGEKEFKAEVISMAGIHHKNVIPFKGYCTSR--------RILVYEFMVNGSLDKWLFAEPG-- .| ||||.|. . .. | .||.|. . | ... | |. |. . .... | .| | .| |.| |||| . | ... VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ -KERLLDWPKR--YEIAVGMARGLTYLHEECTQQ--IIHLDIKPENILLDENFSPKVTDFGLSK-----LVDRDKA-----RVVTNMR--GTPGYLAPEW . .... | .||..|| ||| .. |||.| ||||||.| || |. ||||.. . |. . . || |..|| HHPDPWPLRCRMIHEISCGMC----YLHS---MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEH LN--SNAP---VSTKVDVYSFGIVLLELICGRESF .. .| |..| |||||.||. |. ... . FRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPY |
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| Kinase | SD21_m.AA | LRRK | 30-225 | 23 | 9.6e-31 | 105.98 | In-house | 1-276 (351) | Show / Hide |
Range on Protein: 30-225 Range on HMM: 1-276/351 Sequence Identity: 23% (65 aa) KNFSTKLGNGGFG-QVYEGFLKD---------------------------GSRVAVKVLKEW----------------------------------STQG . ..| |||| || . ... .. ||.|... .. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA EKEFKAEVISMAGIHHKNVIPFKGYCTSRRILVYEFMVNGSLDKWLFAEPGKER-----LLDWPKRYEIAVGMARGLTYLHEECTQQ--IIHLDIKPENI || || | . .| |... ||.| . ...| |.. .|.|.. |... .. ..| ...||. |.|. ||| . ||| | |..|| FREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSPNI LL---D---------ENFSPKVTDFGLSKLVDRDKARVVTNMRGTPGYLAPEWLNSN--APVSTKVDVYSFGIVLLELI || . .. |. |||.| . .. |. . |.||..||| .. | ..|||.||||..| ||. LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELL |
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| Kinase | SD21_m.AA | Pkinase_Tyr | 31-232 | 29 | 1.5e-30 | 104.07 | Pfam | 2-217 (270) | Show / Hide |
Range on Protein: 31-232 Range on HMM: 2-217/270 Sequence Identity: 29% (65 aa) NFSTKLGNGGFGQVYEGFLK-----DGSRVAVKVLKEWSTQGE---KEFKAEVISMAGI-HHKNVIPFKGYCT--SRR---ILVYEFMVNGSLDKWLFAE | ||| | ||.||.| .| .. ||||.||| ... . ..| .|. | . ||.|.. . | || .. ..| |.| .|.|.. | . TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH PGKERLLDWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDENFSPKVTDFGLSKLV-DRDKA-RVVTNMRGTPGYLAPEWLNSNAPVSTKVDV .. |. . .... |.|. ||.. .|| |. |.|..||. |..||||.... . | |. .. . .||| .| . .|| || REDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV YSFGIVLLELIC-GRES-FQ .|||... |.. |.. .. WSFGVLMWEIFTYGEQPTYP |
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| Kinase | SD21_m.AA | TyrKc | 30-305 | 25 | 1.4e-26 | 95.53 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 30-305 Range on HMM: 1-280/280 Sequence Identity: 25% (76 aa) KNFSTKLGNGGFGQVYEGFLKDGSRVAVKVLKEWSTQGEKEFKAEVISMAGI--HHKNVIPFKGYCT---------SRRILVYEFMVNGSLDKWLFAEPG . |||.| ||.||.| .| ||||.||| . ...| | | . ||.|.. . |.|| .| |.| .|.|.. | . . ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP KERLLDWPKRYEIAVGMARGLTYLHEECTQQIIHLDIKPENILLDENFSPKVTDFGLSKLVDRD------KARVVT----NMR--GTPGYLAPEWLNSNA | | ... .... |.| |||. ..|| |. |.|..||. |..|||||. .. | | .. . . .||| . K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG PVSTKVDVYSFGIVLLELI-CGRESFQI---SSSKSSEEWYLPPWASKLVAEGRGLELVDTHLNEEVEYFYQDQANRAIQTALCCIQQDPSNRPSMSRVL .|| ||.|||... |. | . .| .| . ..| .|. .. . .. . . . . ..| . ||..||..| . KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQE------VIEYVKQGYRMPQPPNDY-P-MSF-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIH QML . . ECF |
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| Kinase | SD21_m.AA | MLK | 286-305 | 45 | 2.7e-05 | 14.45 | In-house | 272-291 (291) | Show / Hide |
Range on Protein: 286-305 Range on HMM: 272-291/291 Sequence Identity: 45% (9 aa) CCIQQDPSNRPSMSRVLQML .| .|||..|||.. ..| | QCWNQDPHKRPSFRQIVQHL |
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| Kinase | SD21_m.AA | Dicty4 | 287-307 | 39 | 0.000424 | 9.76 | In-house | 255-277 (277) | Show / Hide |
Range on Protein: 287-307 Range on HMM: 255-277/277 Sequence Identity: 39% (9 aa) CIQQDPSNRPSMSRVLQM--LEG | ||..|||.. ..| || CWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | SD21_m.AA | LRRK | 287-307 | 38 | 0.000452 | 10.28 | In-house | 331-351 (351) | Show / Hide |
Range on Protein: 287-307 Range on HMM: 331-351/351 Sequence Identity: 38% (8 aa) CIQQDPSNRPSMSRVLQMLEG | |.|| .||..| ... |. CWQHDPKKRPHFSQIVKRLSQ |
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| Kinase | SD21_m.AA | TKL-Unique | 287-305 | 42 | 0.001653 | 8.45 | In-house | 272-290 (290) | Show / Hide |
Range on Protein: 287-305 Range on HMM: 272-290/290 Sequence Identity: 42% (8 aa) CIQQDPSNRPSMSRVLQML | .|||.||| . .. | CWHHDPSQRPSFDEIIHRL |
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| Kinase | SD21_m.AA | Pkinase_Tyr | 285-305 | 33 | 0.011514 | 9.65 | Pfam | 250-270 (270) | Show / Hide |
Range on Protein: 285-305 Range on HMM: 250-270/270 Sequence Identity: 33% (7 aa) LCCIQQDPSNRPSMSRVLQML . | ..||..||..| ....| KQCWHYDPEDRPTFSEIHEQL |
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| Kinase | SD21_m.AA | IRAK | 282-305 | 37 | 0.046559 | 3.29 | In-house | 294-317 (317) | Show / Hide |
Range on Protein: 282-305 Range on HMM: 294-317/317 Sequence Identity: 37% (9 aa) QTALCCIQQDPSNRPSMSRVLQML | |.|| . .|..| |.| | QCACCCGHHRANRRCDMAWVMQQL |
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