Gene SD-2b_a-2 (S.moellendorffii)

SD-2b_a-2

Species: S.moellendorffii
Alias: SD-2b_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD2b2

Sequence

Name Sequence Type Origin Length Description Download
SD-2b_a-2.AA Protein None 882 None Fasta, JSON
SD-2b_a-2.NA RNA None 2649 None Fasta, JSON
SD-2b_a-2.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of SD-2b_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin SD-2b_a-2.AA B_lectin 130-230 29 6.7e-23 80.26 Pfam 1-137 (137) Show / Hide 
Range on Protein: 130-230
Range on HMM: 1-137/137
Sequence Identity: 29% (41 aa)

PATVVWRATEK-----L----VHQGAYLNFTE-DGNLELSDRD-G-SL--VWCT--GTAGSGA-Q--ILALEAPGNLVLRT-RN--GTLVWQS--FDHPT
. |||| |        .    . ... | ... |||| |.| . | |   || |  .|.|||.    .. .   |||||..  |  .. .|||  |||||
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DALFPQQQLKP------GMK----LVASVSSE--NTQ
| ..| . |        .|.    |... |..  .. 
DTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin SD-2b_a-2.AA B_lectin 82-204 26 9.4e-12 46.29 SMART 1-126 (126) Show / Hide 
Range on Protein: 82-204
Range on HMM: 1-126/126
Sequence Identity: 26% (37 aa)

RNVLELQKDGEIQAA-----FGFTSRSMTWAVLYSLSAYLVAQPNDEKAQVITPATVVWRA---TEKLVHQG---AYLNFTEDGNLELSDRDGSLVWCTG
.|.|   .            .|| .  |    .. .  |   . .        . |||| |   ....|| |   .||....|||| . |  .. || ..
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ---WCNGIWYKNISNK--------QRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSN

TA-GSGAQILALEAPGNLVLRTRN----GTLVWQSFDHP
|. ..|  .. |   ||.|..  .    |  .|||||||
TTRNNGNYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
B_lectin SD-2b_a-2.AA B_lectin 274-303 21 5.697202 1.47 Pfam 36-72 (137) Show / Hide 
Range on Protein: 274-303
Range on HMM: 36-72/137
Sequence Identity: 21% (8 aa)

SLKIYGQN-G-TV--LWSS-QAFSPVT--DATGFQLL
.| .| .. | .|  .||.    |. .   ..  |..
NLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQ
Kinase SD-2b_a-2.AA TKL 558-829 24 1.6e-66 227.3 In-house 1-364 (364) Show / Hide 
Range on Protein: 558-829
Range on HMM: 1-364/364
Sequence Identity: 24% (94 aa)

IGSGGFGSVYEGVLPD---------GSRVAVKRLENSN----------------------------QGRRQFKVEVKVIGSIHHKNLVRLKGFCSQRPC-
||||||| || |..           |  ||||..   |                            . | ....|.... ...| |.|...|.| . || 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YFLVYEYIANGSLDRWIFKAKAAAAALDWDTRFRVVEDIARGLAYLHE----ECSTK--VLHLDIKPQNILLDESFG-----------
            ...|.||. .|||   .           |. |.| . |||||..|||      |  |  ..| |.|..|||.|| .            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---VKIADFGLSRMVE---QGEMSTVMTM--------------IRGTPGYMAPEWLQ-----------------LRVSDKLDVYSFGIVALEVATGLQAL
   .||.||||||...   . ...  ..|              ..|||..|||| |.                 .  | | ||||||||  |..|. .  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

HTCVSCETSPRFLAAWGYMKLRA----GEMVEMVDAKLRKEIYESTSR-------RSQAERLLKIGMWCIQPDPRQRPRMVEVVKML
           .   . .. . .     ...  .| .|| .| .  ..        .  ... |. ..| ..||..|| . |..| |
----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SD-2b_a-2.AA IRAK 554-753 38 1e-51 178.14 In-house 1-225 (317) Show / Hide 
Range on Protein: 554-753
Range on HMM: 1-225/317
Sequence Identity: 38% (88 aa)

FSK--KIGSGGFGSVYEGVLPDGSR--VAVKRLENS-----NQGRRQFKV---EVKVIGSIHHKNLVRLKGFCSQRPCYFLVYEYIANGSL-DRWIFKAK
|.|  .||.|||| || |.. ..    .|||.| .      |. ...|     |.||  ...|.|.| | |.|..|.|. |||.|..|||| ||    . 
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDG

AAA-AALDWDTRFRVVEDIARGLAYLHEEC-STKVLHLDIKPQNILLDESFGVKIADFGLSRMV---EQGEMSTV---MT-MIRGTPGYMAPEWLQ---L
. .  .| | .|. . . .|.|. .||.    | . | |||. |||||. |  ||.|||| |     .  | .|.   ||  .|||  ||.|| .     
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

RVSDKLDVYSFGIVALEVATGL-QAL
. . |.|||||||| |||.||. ...
QLTKKTDVYSFGIVLLEVLTGCRAVY
Kinase SD-2b_a-2.AA Pkinase 554-749 28 4.2e-51 180.88 Pfam 3-208 (293) Show / Hide 
Range on Protein: 554-749
Range on HMM: 3-208/293
Sequence Identity: 28% (61 aa)

FSKKIGSGGFGSVYEGVLPDGSR-VAVKRLENSNQGRRQFKV-----EVKVIGSIHHKNLVRLKGFCSQRPCYFLVYEYIANG----SLDRWIFKAKAAA
. .|||||.||.||...  . .. ||||... ...   . .      |...  ...|.| |||....  .. . .| ||  .|    .| ..|     . 
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--WRH

AAL--DWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGV----KIADFGLSRMVEQGEMSTVMTMIRGTPGYMAPEWLQ--LRVSDKLD
 ..  ....  ...  |.|||.|.|..   ...| |.||.|||.|.   .    ||.||||.. ..    .. || . |||.|||||...     . | |
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGIVALEVATG
..|.|..  |...|
MWSCGCILYEMLCG
Kinase SD-2b_a-2.AA TKL-Unique 554-749 32 1.5e-44 154.36 In-house 1-224 (290) Show / Hide 
Range on Protein: 554-749
Range on HMM: 1-224/290
Sequence Identity: 32% (74 aa)

FSKKIGSGGFGSVYEGVLPDGSRVAVKRLEN----SNQGRRQFKVEVKVIGSIH-HKNLVRLKGFCS----QRPCYFLVYEYIANGSLDRWIF------K
|..|||.||.|.|| |. . |. ||.|....    ||. .. |. ||...  .| |.|.|.. |.|     . | ...| ||.  |||.  .        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

AKAAAAALDWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDES-----FGVKIADFGLSRMVEQGEMSTVM-------TMIRGTPGYMAPEWL
  .    |..  | . ..|||.|. ||| .  . ..|.|.|..|.|.|.      . .||.|||||.   .   .|.        .   |.. .|||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QL---RVSDKLDVYSFGIVALEVATG
       | | ||||||||  | ||.
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD-2b_a-2.AA MLK 552-742 30 5.7e-42 143.4 In-house 1-225 (291) Show / Hide 
Range on Protein: 552-742
Range on HMM: 1-225/291
Sequence Identity: 30% (69 aa)

KGFSKKIGSGGFGSVYEGVLPDGSR-----VAVKRLE-------NSNQGRRQFKVEVKVIGSIHHKN----LVRLKGFCSQRPC-YFLVYEYIANGSLDR
  |...||||.||.|. |.   . .     ||||| .        .   ...|. |..    . |.|     ....| |.| || ...| ||...||| .
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WIFKAKAAAA----------ALDWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDE------SFGVKIADFGLSRMVEQGEMSTVMTMIRGTP
 .  |.   .            | |  ..   ..|||..|||..   .. | |.|..|||.||         .||.|||.||.. | .  | |.  .||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYMAPEWL----QLRVSDKLDVYSFGIV
 .|||| .      ..| | ||.|.|.|
AWMAPEVIQQFRCEKYSEKCDVWSWGVV
Kinase SD-2b_a-2.AA Dicty4 554-749 35 3.3e-38 125.16 In-house 3-213 (277) Show / Hide 
Range on Protein: 554-749
Range on HMM: 3-213/277
Sequence Identity: 35% (75 aa)

FSKKIGSGGFGSVYEGVLPDGSRVAVKRLENSNQGR-----RQFKVEVKVIGSIHHKNLVRLKGFCS----QRPCYFLVYEYIANGSLDRWIFK---AKA
. ..||.|.||.|| |    |. |||| | | ||.        |. ||.  ..| | |.. ..| |     . .    | ||   |.| . . .    . 
IEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

AAAALDWDTRFR---VVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFGLSRMVEQGEMSTV--MTMIRGTPGYMAPEWLQLRV-SDKLD
    ||| .. |      |.|||...||. | . ..|.|.|. |.| |... ||..|||||..   .|. .   ||.. |||..|||| .. .    | |
QSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC-GTPCWMAPEVMMHQPYNEKAD

VYSFGIVALEVATG
|||||||  | .|.
VYSFGIVLWEILTR
Kinase SD-2b_a-2.AA S_TKc 552-836 23 3.1e-37 130.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 552-836
Range on HMM: 1-231/231
Sequence Identity: 23% (70 aa)

KGFSKKIGSGGFGSVYEGVLPD-GSRVAVKRLENSNQGRRQFKVEVKVIGSIHHKNLVRLKGFCSQRPCYFLVYEYIAN--GSLDRWIFKAKAAAAA--L
  . .|||.|.||.|| ..  . | .||.|..       .... |...  . ||.|.|.|....    ....| ||. .  |.| . | | .       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFGLSRMVEQGEMSTVMTMIRGTPGYMAPEWLQLRVSD-KLDVYSFGIVALE
.  .  ...  |...|.|.|.     ..| |.||.||||||   .||.||||.| .         | . ||| ||||| |    .  | |..|.|..  |
PE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYE

VATGLQALHTCVSCETSPRFLAAWGYMKLRAGEMVEMVDAKLRKEIYESTSRRSQAERLLKIGMWCIQPDPRQRPRMVEVVK--MLEGATPVM
 ..|    .            . .  ..                            . .. . . | | ||..||   |. .  ..  . | .
MLCGYPPFP---------QMQMMFKKIG---------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD-2b_a-2.AA STE 554-749 23 8.3e-37 127.53 In-house 1-264 (359) Show / Hide 
Range on Protein: 554-749
Range on HMM: 1-264/359
Sequence Identity: 23% (64 aa)

FSK--KIGSGGFGSVYEGVLPD----------------GSRVAVKRLENSNQG------------------RRQFKVEVKVIGSIH--HKNLVRLKGFCS
. .  |||.|.||.|| ..  .                | ..|.|... .|.                   . |.. |.|.    .  |.| |.  | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-------QRPCYFLVYEYIANGSLDRWIFKAKAAAAALD----------WDTRFRVVEDIARG-LAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFG
       ..   ... ||...||||  | . .     |.           .   ... .| .| |.|||.     . | ||||.||||     ||..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSRMVEQG--------------EMSTVMTMIRGTPGYMAPEWLQLRVSD-------KLDVYSFGIVALEVATG
..  ...                |.   . . ||| .|||| .| . ..       | |..|.|....| |||
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATG
Kinase SD-2b_a-2.AA RIPK 558-749 30 2.4e-35 117.91 In-house 1-224 (290) Show / Hide 
Range on Protein: 558-749
Range on HMM: 1-224/290
Sequence Identity: 30% (70 aa)

IGSGGFGSVYEGVLPDGSRVAVKRLENSNQ--------GRRQFKVEVKVIGSIHHKNLVRLKGFCSQR-----PC-YFLVYEYIANGSLDRWIFKAKA--
.|.|||| |.  .  .   ...|   .. .         | . | |.|   .. ... |...||| .      .  | .| || .||||     ..|   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWH-FLHTKWPY

AAAALDWDTRFRVVEDIARGLAYLHEECSTK--VLHLDIKPQNILLDESFGVKIADFGLSRMVEQGEMSTVMT--------MI-----R-GTPGYMAPEW
    . |. |.| .  |..|  |||   | .  ..|.| ||.|||.|  | ||||||||.      ..|....         .     | ||  ||.|| 
QHHPDPWPLRCRMIHEISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWM---MWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEH

LQ----LR---VSDKLDVYSFGIVALEVATG
.      .   |. | |||||.||  || |.
FRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQ
Kinase SD-2b_a-2.AA LISK 557-745 28 2.6e-35 112.02 In-house 1-231 (296) Show / Hide 
Range on Protein: 557-745
Range on HMM: 1-231/296
Sequence Identity: 28% (67 aa)

KIGSGGFGSVYEGVLP-DGSRVAVKRLE------NSNQGRRQFKVEVKVIGSIHHKNLVRLKGFCSQ-RPCYFLVYEYIANGSLDRWIFKAKAAAAALDW
.||.|.||.|| | .  .|. .|.| ..      | .  .. .. ||... .. |.| |.  | | .    ...| |||  | | . ... .     | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

DTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDES----FGVKIADFGLSRMVEQGEMS---------------------------------TVM
. | .   |||.|..|||   | ...| | | .|.|..|.    . .|..|||. ||... . |                                   |
PQRVKIALDIACGMSYLH---SMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TMIRGTPGYMAPEWL-QLRVSDKLDVYSFGIVALE
|.  |||  |||| | .   ... ||.||||| .|
TIC-GTPYWMAPEMLLGQSYDESCDVFSFGIVLCE
Kinase SD-2b_a-2.AA LRRK 552-742 25 2.9e-32 111.41 In-house 1-271 (351) Show / Hide 
Range on Protein: 552-742
Range on HMM: 1-271/351
Sequence Identity: 25% (70 aa)

KGFSKKIGSGGFG-SVYEGVLPD---------------------------GSRVAVKRLEN----------SNQG-------------------------
  . ..||.|||| .|| . . .                           .. ||.| ..           .. .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

RRQFKVEVKVIGSIHHKNLVRLKGFCSQRPCYFLVYEYIANGSLDRWIFKAKAAA-----AALDWDTRFRVVEDIARGLAYLHEECSTK--VLHLDIKPQ
 | |  || .. . .| |.| ||||| . .|  .| ||. .|.|.. ... |  .     | ..| .. ... .||.|..|||   | .  ..| | |. 
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSP

NILL---D---------ESFGVKIADFGLSRMVEQGEMSTVMTMIRGTPGYMAPEWLQ----LRVSDKLDVYSFGIV
||||   .         .   .||||||.|||  |   ..|     |.||.|||| ..       ..| |.||||..
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMI
Kinase SD-2b_a-2.AA Dicty4-Unclassified 554-749 36 9.4e-32 106.0 In-house 3-204 (263) Show / Hide 
Range on Protein: 554-749
Range on HMM: 3-204/263
Sequence Identity: 36% (76 aa)

FSKKIGSGGFGSVYEGVLPDGSRVAVKRL-ENSNQGR----RQFKVEVKVIGSIHHKNLVRLKGFC----SQRPCYFLVYEYIANGSLDRWIF-KAKAAA
  . || | |  |. |.   |  |||| . ||. . |      || || . ||| | |||...| |    | .  .  | | .  | |   |  |     
IDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

AALDWDT--RFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFGLSRMVEQGEMSTVMTMIRGTPGYMAPEWLQLRV-SDKLDVYSFG
  .  |     ..  |||.|...||   .  . | |||  |||.|  | .||||||.|| .   .    || | |||   .|| |       | ||||..
QPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

IVALEVATG
..  | |||
MMLYELATG
Kinase SD-2b_a-2.AA Pkinase_Tyr 554-742 31 1.3e-28 97.54 Pfam 3-203 (270) Show / Hide 
Range on Protein: 554-742
Range on HMM: 3-203/270
Sequence Identity: 31% (64 aa)

FSKKIGSGGFGSVYEGVLP-----DGSRVAVKRL-ENSNQG---RRQFKVEVKVIGSI-HHKNLVRLKGFCS-QRPC--YFLVYEYIANGSLDRWIFKAK
| ||.|.| ||.||.|..      ..  |||| | |.. .    |. |  |.|.  .. ||.|.||| | |. |.    ...| || ..|.|.    | .
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

AAAAALDWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFGLSRMVEQGEMS-TVMTMIRGTPGYMAPE-WLQLRVSDKLDVYS
    .|.  .      .||.|..||..       | |.   |.|..|.. |||.||||.| ..  .   .. .  .     |||| .   . . | ||.|
EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGIV
||..
FGVL
Kinase SD-2b_a-2.AA TyrKc 554-829 25 1.1e-25 92.55 SMART 3-280 (280) Show / Hide 
Range on Protein: 554-829
Range on HMM: 3-280/280
Sequence Identity: 25% (79 aa)

FSKKIGSGGFGSVYEGVLPDGSRVAVKRLENSNQGRRQFKVEVKVIGSI--HHKNLVRLKGFCSQR-------PCYFLVYEYIANGSLDRWIFKAKAAAA
. ||.|.| || ||.|..     |||| | ..   |. |  | ..  ..  ||.|.||| | |.|        . ...| || ..|.|.  . | .    
LGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

ALDWDTRFRVVEDIARGLAYLHEECSTKVLHLDIKPQNILLDESFGVKIADFGLSRMVEQG-------EMSTV----MTM----IRGTPGYMAPEWLQLR
 | ...      .||.| .|||.    .. | |.   |.|..| . |||.|||||| .. .       .. ..     .     ||     |||| .. .
-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR----WMAPECINYG

V-SDKLDVYSFGIVALEVATGLQALHTC-----VSCETSPRFLAAWGYMKLRAGEMVEMVDAKLRKEIYESTSRRSQAERLLKIGMWCIQPDPRQRPRMV
. . | ||.|||..  |. |  |  .       .| .   ... . ..|.  .    .|             . .  .|    |  .| . || .||.. 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMS------------FVCCPDEMYQ-IMKQCWHEDPEDRPTFS

EVVKML
|... .
EIHECF
Kinase SD-2b_a-2.AA MLK 811-829 36 0.00015 11.85 In-house 273-291 (291) Show / Hide 
Range on Protein: 811-829
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CIQPDPRQRPRMVEVVKML
| ..||..|| . ..|. |
CWNQDPHKRPSFRQIVQHL
Kinase SD-2b_a-2.AA Dicty4-Unclassified 810-829 40 0.001074 8.49 In-house 244-263 (263) Show / Hide 
Range on Protein: 810-829
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCIQPDPRQRPRMVEVVKML
||   ||. || | .... |
WCWHNDPNKRPTMNQIIQYL
Kinase SD-2b_a-2.AA Dicty4 810-831 37 0.002186 7.35 In-house 254-277 (277) Show / Hide 
Range on Protein: 810-831
Range on HMM: 254-277/277
Sequence Identity: 37% (9 aa)

WCIQPDPRQRPRMVEVVKM--LEG
||  .|| .|| . |...   || 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase SD-2b_a-2.AA LRRK 809-831 39 0.003879 6.93 In-house 329-351 (351) Show / Hide 
Range on Protein: 809-831
Range on HMM: 329-351/351
Sequence Identity: 39% (9 aa)

MWCIQPDPRQRPRMVEVVKMLEG
..| | ||..|| . ..|| |. 
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase SD-2b_a-2.AA Pkinase_Tyr 811-829 36 0.013647 9.4 Pfam 252-270 (270) Show / Hide 
Range on Protein: 811-829
Range on HMM: 252-270/270
Sequence Identity: 36% (7 aa)

CIQPDPRQRPRMVEVVKML
| ..|| .||.. |.. .|
CWHYDPEDRPTFSEIHEQL
Kinase SD-2b_a-2.AA LISK 802-829 32 0.019754 3.48 In-house 269-296 (296) Show / Hide 
Range on Protein: 802-829
Range on HMM: 269-296/296
Sequence Identity: 32% (9 aa)

ERLLKIGMWCIQPDPRQRPRMVEVVKML
. .|.. ..|.  ||. ||   |.|. |
PPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase SD-2b_a-2.AA TKL-Unique 811-829 42 0.180551 1.17 In-house 272-290 (290) Show / Hide 
Range on Protein: 811-829
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CIQPDPRQRPRMVEVVKML
|  .|| |||   |... |
CWHHDPSQRPSFDEIIHRL