Gene SD2b2_i (S.moellendorffii)

SD2b2_i

Species: S.moellendorffii
Alias: SD2b2_i
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD2b2

Sequence

Name Sequence Type Origin Length Description Download
SD2b2_i.AA Protein None 607 None Fasta, JSON
SD2b2_i.NA RNA None 1824 None Fasta, JSON
SD2b2_i.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of SD2b2_i.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SD2b2_i.AA TKL 289-569 21 1.7e-58 200.68 In-house 1-364 (364) Show / Hide 
Range on Protein: 289-569
Range on HMM: 1-364/364
Sequence Identity: 21% (86 aa)

LGEGGFGMVFKGNLSD---------GTTVAVKRMDV------------------------EIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPS-
.|.|||| |.||..           |..||||.. .                        . . .   ..... |.... ..|| |.||. |.|. .|. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------SLLVYEYMSNGALDKWIFRKDSRFLDWSQRHQVAVDVARGLTYLHE----GCREQ--VLHLDIKPQNILLDENLR-------------
              .|.||...| |   .         |.||.. | |.|||. |||     .|.    ..| |.|..|||.|||..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-ARIADFGLSKLAERGKSYAVTA------------------MRGTPGYMAPEWL-----------------HTKVTDRTDVYSFGIVLLELLSSRKSLEI
 . |.|||||.  .. ..   |.                   .|||..|||| |                 . . . ..||||||||| |.|. ..    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

QKHSSSVASTSAASSSSASSQGVFILGHTAARLFHSGDV-------------STLVDRGLEVDLS--------------VAERFTKIALWCIQEDSAKRP
                                 ..  .              .  .|.||   .               . ... |.. .| ..|  |||
--------------------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP

SIGNALAML
|    |  |
SFQEILKRL
Kinase SD2b2_i.AA IRAK 283-480 36 7.6e-48 165.28 In-house 1-219 (317) Show / Hide 
Range on Protein: 283-480
Range on HMM: 1-219/317
Sequence Identity: 36% (80 aa)

FAKKSMLGEGGFGMVFKGNLSDGT-TVAVKRMDVEIEGS-NEGQQQFKA---EVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGAL-DKWIFRKDS
|.|   .|||||| |..| ..  | ..|||.   . . | ||  |.| .   |. .  ..|| |.| | |.|. ..   |||.||.||.| |    .. .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

RF---LDWSQRHQVAVDVARGLTYLHEGC-REQVLHLDIKPQNILLDENLRARIADFGLSKL-----AERGKSY---AVTAMRGTPGYMAPEWLH---TK
     | | ||. ..   |.|. .||.      . | |||. |||||... . |.||||        .    .|    .   |||  ||.|| .     .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VTDRTDVYSFGIVLLELLS
 | .||||||||||||.|.
LTKKTDVYSFGIVLLEVLT
Kinase SD2b2_i.AA Pkinase 283-569 21 6.4e-46 163.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 283-569
Range on HMM: 1-293/293
Sequence Identity: 21% (73 aa)

FAKKSMLGEGGFGMVFKG-NLSDGTTVAVKRMDVEIEGSNEGQQQFK-AEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNG----ALDKWIFRKDS
. ... .|.|.|| |.|. . ..| .||||..... | |.. |. .. .|.    ...| | |.|....  ...  .| ||. .|     |  .| ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RFL--DWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDENLRA----RIADFGLSKLAERGKSYAVTAMRGTPGYMAPEW-L-HTKVTDRTDV
. .  .. .   ..  ..||| |.|. .   ..| |.||.|||.|.|       .|.||||.|...  ..   |   |||.|||||. . ... . . |.
GCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGIVLLELLSSRKSLEIQKHSSSVASTSAASSSSASSQGVFILGHTAARLFHSG------DVSTLVDRGLEVDLSVA---------------------
.|.|..| |.|. |                                     .| .       |   ...| .. .|.                       
WSCGCILYEMLCGR------------------------------------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF

----ERFTKIALWCIQEDSAKRPSIGNALAM--L
    | . ..  ||.. | .|||..  .|    .
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase SD2b2_i.AA Dicty4 283-479 32 4.8e-44 144.89 In-house 1-211 (277) Show / Hide 
Range on Protein: 283-479
Range on HMM: 1-211/277
Sequence Identity: 32% (70 aa)

FAKKSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEG-SNEGQQQFKAEVLSIGSIRHYNLVQLRGFCI----HGPSSLLVYEYMSNGALDKWIFRK---
 .. . .|.|.|| |.||.   |. |||| .    .. . .  . |..||   ..||| |.... | |.    | .. . | |||. | | . . ..   
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYS-LLHDKPS

---DSRFLDWSQRHQ---VAVDVARGLTYLHE-GCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAV--TAMRGTPGYMAPEWLHTKV-TD
   .|  |||. . .    | |.|||...||.  ..  ..|.|.|. |.| |.|.|. ..|||||..  ....     ... |||..|||| .  .  . 
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

RTDVYSFGIVLLELL
  ||||||||| |.|
KADVYSFGIVLWEIL
Kinase SD2b2_i.AA TKL-Unique 287-481 30 1.7e-41 144.15 In-house 3-224 (290) Show / Hide 
Range on Protein: 287-481
Range on HMM: 3-224/290
Sequence Identity: 30% (70 aa)

SMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIR-HYNLVQLRGFCI----HGPSSLLVYEYMSNGALDKWIFR--------
. .||||.| |.||    |. ||.|.  .. . |||  | |. ||  .  .. | |.|.. |.|.    . | . .| ||.. | |.. . .        
NKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

KDSRFLDWSQRHQVAVDVARGLTYLHEGCREQ--VLHLDIKPQNILLDEN-----LRARIADFGLSKLAERGKSYAVT--------AMRGTPGYMAPEWL
...  |...|| . | |.|.|. |||   ...  ..|.|.|..|.|.|.|     ....|.||||||.. .     ..           |.. .|||| |
NNNCKLNMQQRVKMAIDIAQGMYYLH---HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

HT---KVTDRTDVYSFGIVLLELLSS
     . .   ||||||||| |....
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD2b2_i.AA MLK 283-480 27 2.4e-40 137.67 In-house 1-231 (291) Show / Hide 
Range on Protein: 283-480
Range on HMM: 1-231/291
Sequence Identity: 27% (65 aa)

FAKKSMLGEGGFGMVFKGNLSDGT----TVAVKRMDVEIEGSNEG----QQQFKAEVLSIGSIRHYN----LVQLRGFCIHGPS-SLLVYEYMSNGALDK
.  .  .|.|.|| |.||.    .    .||||| . .|. .       |..|. |.     ..| |     .|..| |.  |.  ..| ||...| |  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WIFRKDS------------RFLDWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDE------NLRARIADFGLSK-LAERGKSYAVTAMRGTP
 .  ..|            |  | ..  . |...|||. |||.  . .. | |.|..|||.||      .. ..|.|||.|. . ...     . ..||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYMAPEWL----HTKVTDRTDVYSFGIVLLELLS
 .|||| .    ..|..   ||.|.|.|| |.|.
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase SD2b2_i.AA S_TKc 283-569 21 2.6e-36 127.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 283-569
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

FAKKSMLGEGGFGMVFKGNLSD-GTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSN--GALDKWIFRKDSRF-
. .   .|.|.|| |.|.   . |  ||.|...          .... |.    . .| |.|.| ... .  .  .| ||...  | | . | .. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPGYMAPEWLHTKVTD-RTDVYSFGIV
   ..  .   ..  ....| |.|.    ...| |.||.||||||  .  |.||||...         | . ||| ||||| |  . .  . |..|.|..
RFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

LLELLSSRKSLEIQKHSSSVASTSAASSSSASSQGVFILGHTAARLFHSGDVSTLVDRGLEVDLSVAERFTKIALWCIQEDSAKRPSIGNALA-------
| |.|. .   .                     |   .. .                          . .  .   | | | .|||..  ||.       
LYEMLCGYPPFP---------------------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

--ML
   .
HPWF
Kinase SD2b2_i.AA LRRK 283-480 23 1.5e-35 123.27 In-house 1-277 (351) Show / Hide 
Range on Protein: 283-480
Range on HMM: 1-277/351
Sequence Identity: 23% (67 aa)

FAKKSMLGEGGFG-MVFKGNLSD---------------------------GTTVAVKRMDVE-------------------------------IEGSNEG
. . ...|.||||  |..... .                           ...||.| ....                               .|.. . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGALDKWIFRKD-SRF------LDWSQRHQVAVDVARGLTYLHEGCREQ--VLHLDIKPQ
 . |  ||  . . .| |.|.| ||||| .   .| ||...|.|.. .. |  ..|      ..|. ....|...|.|. |||   .    ..| | |. 
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSP

NILL---D---------ENLRARIADFGLSK-LAERGKSYAVTAMRGTPGYMAPEWLH----TKVTDRTDVYSFGIVLLELLS
||||   .         ..  | |||||.|       .. ..  . |.||.|||| .        |. .|.||||..| |||.
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase SD2b2_i.AA Pkinase_Tyr 283-480 29 4.6e-34 115.98 Pfam 1-209 (270) Show / Hide 
Range on Protein: 283-480
Range on HMM: 1-209/270
Sequence Identity: 29% (63 aa)

FAKKSMLGEGGFGMVFKGNLS-----DGTTVAVKRMDVEIEGSNEGQ---QQFKAEVLSIGSI-RHYNLVQLRGFCI-HGPS--SLLVYEYMSNGALDKW
  .  .|||| ||.|.|| .      ....|||| .    ||. . |   . | .|.    .. .| |.|.| | |. .| .   ..| ||| .| |.. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IFRK--DSRFLDWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPG---YMAPE-WLHTKVTD
  ..  | . |. ..  | ....|.|. ||..       | |.   |.|..||. ..|.||||... .    | ...  |..     |||| . . | | 
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTT

RTDVYSFGIVLLELLS
 .||.|||... |...
KSDVWSFGVLMWEIFT
Kinase SD2b2_i.AA TK 283-480 16 1.6e-33 109.16 In-house 1-389 (486) Show / Hide 
Range on Protein: 283-480
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

FAKKSMLGEGGFG---MVFKGNLSDG--------------------------TTVAVKRMDVEIEGSNEGQQQ--------------FKAEVLSIGS--I
      |||| ||   .|.|| . ..                          |.|||| .  . . | | ...              . .|     .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHYNLVQLRGFCIHG------------PSSLLVYEYMSNGA----LDKWIF--RKDSRF-----------------------------------------
.| |.|.| | | .|            .  ..| |||..|     |...    |.. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWSQRHQVAVDVARGLTYLHEG----CREQVLHLDIKPQNILLDENLR-----------ARIADFG--
                               |.  |..  ....|.|. |||.        .. | |.   |.|..||..           ..|||||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSKLAERGKSYAVTAMRGTPG-------------------------YMAPEWLHTKV----------TDRTDVYSFGIVLLELLS
      |..  .... | ..  .||..                         .|||| | ..|          |  .||.|||... |...
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD2b2_i.AA DRK 290-479 36 7.8e-33 108.56 In-house 8-196 (258) Show / Hide 
Range on Protein: 290-479
Range on HMM: 8-196/258
Sequence Identity: 36% (70 aa)

GEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGALDKWIFRKDSRFLDWSQRHQVAV
| |..| || |    || ||||..    .   .  . |. |.  .   || | .|  | |   |. . . |||. | | . |   .|  .||. . | . 
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYN-ILHDESIEMDWPLMKQMMF

DVARGLTYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSK--LAERGKSYAVTAMRGTPGYMAPEWLHTKV-TDRTDVYSFGIVLLELL
|.|.|..||| .|   ..| | |  | | ||. .  .||||||      . .  | |.  |||.  ||| |     |   |||||.||| |..
DCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase SD2b2_i.AA Dicty4-Unclassified 286-479 34 4.3e-31 103.71 In-house 4-202 (263) Show / Hide 
Range on Protein: 286-479
Range on HMM: 4-202/263
Sequence Identity: 34% (71 aa)

KSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSN-EGQQQFKAEVLSIGSIRHYNLVQLRGFCIHG----PSSLLVYEYMSNGALDKWIF-----RKD
   .|.| |  | |||   |  |||| .         |  | ||.||   ||| | |||...| ||           | | |  | |   |      .. 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

SRFLDWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPGYMAPEWL-HTKVTDRTDVYSFGIV
.  ||      .| |.|.|. .||      . | |||  |||.| .  ..|||||.|   .    .  |.  |||   .|| | |   . . ||||....
PIKLDDTLIIKYAFDIAQGMQHLHT---RNFIHRDIKSSNILMDKHFNIKIADFGISRVID--FNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LLELL
| ||.
LYELA
Kinase SD2b2_i.AA STE 283-479 21 3.6e-30 103.76 In-house 1-262 (359) Show / Hide 
Range on Protein: 283-479
Range on HMM: 1-262/359
Sequence Identity: 21% (57 aa)

FAKKSMLGEGGFGMVFKGNLSD----------------GTTVAVKRMDVEIEGS--------------NEGQQQFKAEVLSIGSIR--HYNLVQLRGFCI
. . ...|.|.|| |.|.   .                |. .|.|.|..| . .              .| .||.. |.      .  | | |.  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HG-------PSSLLVYEYMSNGALDKWIFRKDSRFLD------------WSQRHQVAVDVARG-LTYLHEGCREQVLHLDIKPQNILLDENLRARIADFG
..        .  .. |||..| ||. | .| ... .             ||   ..... .| | |||.     . | ||||.||||     . ..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKLAERG-------------KSYA-VT-AMRGTPGYMAPEWLH-------TKVTDRTDVYSFGIVLLELL
...  .               .. .  .  . ||| .|||| .         . . . |..|.|....|..
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase SD2b2_i.AA TyrKc 283-569 21 4.2e-27 97.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 283-569
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

FAKKSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSI--RHYNLVQLRGFCIHG-------PSSLLVYEYMSNGALDKWIFR
  .. .|||| || |.|| ..  ..|||| .  .       .. |  |     ..  .| |.|.| | |...       .  ..| |||..|.|.. . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KDSRFLDWSQRHQVAVDVARGLTYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERG-------KSYAVTAMRGTPG-----YMAPEWL-HT
.  . | ... .. ....|.|  |||.    .. | |.   |.|..||....|.|||||.  . .       . | ..  .|. .      |||| . . 
HRPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KVTDRTDVYSFGIVLLELLSSRKSLEIQ-----KHSSSVASTSAASSSSASSQG----VFILGHTAARLFHSGDVSTLVDRGLEVDLSVAERFTKIALWC
| |  .||.|||... |...  ..         .  . |     .       .                                    .| .. | ..|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------FVCCPDEMYQ-IMKQC

IQEDSAKRPSIGNALAML
 .|| ..||.  .    .
WHEDPEDRPTFSEIHECF
Kinase SD2b2_i.AA Dicty4-Unclassified 539-569 25 0.018058 4.23 In-house 233-263 (263) Show / Hide 
Range on Protein: 539-569
Range on HMM: 233-263/263
Sequence Identity: 25% (8 aa)

SVAERFTKIALWCIQEDSAKRPSIGNALAML
..   . |   ||  .|  |||..      |
NCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase SD2b2_i.AA DRK 551-571 42 0.086114 1.89 In-house 238-258 (258) Show / Hide 
Range on Protein: 551-571
Range on HMM: 238-258/258
Sequence Identity: 42% (9 aa)

CIQEDSAKRPSIGNALAMLEG
|  ||   |||    |  || 
CWNEDPQHRPSMQECLERLEA
Kinase SD2b2_i.AA TK 547-569 21 0.110409 0.55 In-house 464-486 (486) Show / Hide 
Range on Protein: 547-569
Range on HMM: 464-486/486
Sequence Identity: 21% (5 aa)

IALWCIQEDSAKRPSIGNALAML
. . | ..| ..||.    . .|
LMQQCWHYDPEDRPTFSQLHEQL