Gene SD2b2_h (S.moellendorffii)

SD2b2_h

Species: S.moellendorffii
Alias: SD2b2_h
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD2b2

Sequence

Name Sequence Type Origin Length Description Download
SD2b2_h.AA Protein None 630 None Fasta, JSON
SD2b2_h.NA RNA None 1893 None Fasta, JSON
SD2b2_h.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of SD2b2_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SD2b2_h.AA TKL 313-592 21 1.4e-59 204.23 In-house 1-364 (364) Show / Hide 
Range on Protein: 313-592
Range on HMM: 1-364/364
Sequence Identity: 21% (86 aa)

LGEGGFGMVFKGNLSD---------GTTVAVKRMDV------------------------EIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPS-
.|.|||| |.||..           |..||||.. .                        . . .   ..... |.... ..|| |.||. |.|. .|. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------SLLVYEYMSNGALDKWIFPKDSRFLDWSQRHQVAVDVARGLAYLHE----GCREQ--VLHLDIKPQNILLDENLR-------------
              .|.||...| |   .         |.||.. | |.|||..|||     .|.    ..| |.|..|||.|||..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-ARIADFGLSKLAERGKSYAVTA------------------MRGTPGYMAPEWL-----------------HTKVTDRTDVYSFGIVLLELLSSRKSLEI
 . |.|||||.  .. ..   |.                   .|||..|||| |                 . . . ..||||||||| |.|. ..    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

QKHSSSVASTSGASSSASSQGVFILGHTAARLFHSGDV-------------ATLVDRDLEVDLS--------------VAERFAKIGLWCIQEDPAKRPS
                                ..  .              .  .|. |   .               . ....|.  .| ..|| ||||
-------------------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS

IGNALAML
    |  |
FQEILKRL
Kinase SD2b2_h.AA IRAK 307-504 36 5.3e-47 162.46 In-house 1-219 (317) Show / Hide 
Range on Protein: 307-504
Range on HMM: 1-219/317
Sequence Identity: 36% (80 aa)

FAKKSMLGEGGFGMVFKGNLSDGT-TVAVKRMDVEIEGS-NEGQQQFKA---EVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGALDKWIFPKD-S
|.|   .|||||| |..| ..  | ..|||.   . . | ||  |.| .   |. .  ..|| |.| | |.|. ..   |||.||.||.|       | .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

RF---LDWSQRHQVAVDVARGLAYLHEGC-REQVLHLDIKPQNILLDENLRARIADFGLSKL-----AERGKSY---AVTAMRGTPGYMAPEWLH---TK
     | | ||. ..   |.|. .||.      . | |||. |||||... . |.||||        .    .|    .   |||  ||.|| .     .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VTDRTDVYSFGIVLLELLS
 | .||||||||||||.|.
LTKKTDVYSFGIVLLEVLT
Pkinase SD2b2_h.AA Pkinase 307-592 22 7.2e-46 163.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 307-592
Range on HMM: 1-293/293
Sequence Identity: 22% (72 aa)

FAKKSMLGEGGFGMVFKG-NLSDGTTVAVKRMDVEIEGSNEGQQQFK-AEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNG----ALDKWIFPKDS
. ... .|.|.|| |.|. . ..| .||||..... | |.. |. .. .|.    ...| | |.|....  ...  .| ||. .|     |  .|  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RFL--DWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDENLRA----RIADFGLSKLAERGKSYAVTAMRGTPGYMAPEW-L-HTKVTDRTDV
. .  .. .   ..  ..|||.|.|. .   ..| |.||.|||.|.|       .|.||||.|...  ..   |   |||.|||||. . ... . . |.
GCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGIVLLELLSSRKSLEIQKHSSSVASTSGASSSASSQGVFILGHT------AARLFHSGDVATLVDRDLEVDLSVA-----------------ERFAK
.|.|..| |.|.                           | ..  .         .  .  .  . ...| . . |.                  | . .
WSCGCILYEMLC---------------------------GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

IGLWCIQEDPAKRPSIGNALAM--L
.  ||.. ||.|||..  .|    .
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase SD2b2_h.AA Dicty4 307-503 32 1.1e-42 140.23 In-house 1-211 (277) Show / Hide 
Range on Protein: 307-503
Range on HMM: 1-211/277
Sequence Identity: 32% (70 aa)

FAKKSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEG-SNEGQQQFKAEVLSIGSIRHYNLVQLRGFCI----HGPSSLLVYEYMSNGALDKWIFP----
 .. . .|.|.|| |.||.   |. |||| .    .. . .  . |..||   ..||| |.... | |.    | .. . | |||. | | . .      
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

-KDSRFLDWSQRHQ---VAVDVARGLAYLHE-GCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAV--TAMRGTPGYMAPEWLHTKV-TDR
 ..|  |||. . .    | |.|||...||.  ..  ..|.|.|. |.| |.|.|. ..|||||..  ....     ... |||..|||| .  .  .  
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

TDVYSFGIVLLELL
 ||||||||| |.|
ADVYSFGIVLWEIL
Kinase SD2b2_h.AA MLK 307-504 27 7.4e-41 139.48 In-house 1-231 (291) Show / Hide 
Range on Protein: 307-504
Range on HMM: 1-231/291
Sequence Identity: 27% (65 aa)

FAKKSMLGEGGFGMVFKGNLSDGT----TVAVKRMDVEIEGSNEG----QQQFKAEVLSIGSIRHYN----LVQLRGFCIHGPS-SLLVYEYMSNGALDK
.  .  .|.|.|| |.||.    .    .||||| . .|. .       |..|. |.     ..| |     .|..| |.  |.  ..| ||...| |  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WIFPKDS------------RFLDWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDE------NLRARIADFGLSK-LAERGKSYAVTAMRGTP
 .  ..|            |  | ..  . |...|||..|||.  . .. | |.|..|||.||      .. ..|.|||.|. . ...     . ..||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYMAPEWL----HTKVTDRTDVYSFGIVLLELLS
 .|||| .    ..|..   ||.|.|.|| |.|.
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase SD2b2_h.AA TKL-Unique 311-505 30 1.4e-40 140.83 In-house 3-224 (290) Show / Hide 
Range on Protein: 311-505
Range on HMM: 3-224/290
Sequence Identity: 30% (70 aa)

SMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIR-HYNLVQLRGFCI----HGPSSLLVYEYMSNGALDKWIFP--------
. .||||.| |.||    |. ||.|.  .. . |||  | |. ||  .  .. | |.|.. |.|.    . | . .| ||.. | |.. .          
NKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

KDSRFLDWSQRHQVAVDVARGLAYLHEGCREQ--VLHLDIKPQNILLDEN-----LRARIADFGLSKLAERGKSYAVT--------AMRGTPGYMAPEWL
...  |...|| . | |.|.|. |||   ...  ..|.|.|..|.|.|.|     ....|.||||||.. .     ..           |.. .|||| |
NNNCKLNMQQRVKMAIDIAQGMYYLH---HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

HT---KVTDRTDVYSFGIVLLELLSS
     . .   ||||||||| |....
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD2b2_h.AA S_TKc 307-592 21 5.7e-37 130.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 307-592
Range on HMM: 1-231/231
Sequence Identity: 21% (65 aa)

FAKKSMLGEGGFGMVFKGNLSD-GTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSN--GALDKWIFPKDSRF-
. .   .|.|.|| |.|.   . |  ||.|...          .... |.    . .| |.|.| ... .  .  .| ||...  | | . |  . ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPGYMAPEWLHTKVTD-RTDVYSFGIV
   ..  .   ..  ....|.|.|.    ...| |.||.||||||  .  |.||||...         | . ||| ||||| |  . .  . |..|.|..
RFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

LLELLSSRKSLEIQKHSSSVASTSGASSSASSQGVFILGHTAARLFHSGDVATLVDRDLEVDLSVAERFAKIGLWCIQEDPAKRPSIGNALA--------
| |.|. .   .                    |   .. .                          . .  .   | | ||.|||..  ||.        
LYEMLCGYPPFP--------------------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

-ML
  .
PWF
Kinase SD2b2_h.AA LRRK 307-504 23 1.4e-36 126.9 In-house 1-277 (351) Show / Hide 
Range on Protein: 307-504
Range on HMM: 1-277/351
Sequence Identity: 23% (67 aa)

FAKKSMLGEGGFG-MVFKGNLSD---------------------------GTTVAVKRMDVE-------------------------------IEGSNEG
. . ...|.||||  |..... .                           ...||.| ....                               .|.. . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGALDKWIF-PKDSRF------LDWSQRHQVAVDVARGLAYLHEGCREQ--VLHLDIKPQ
 . |  ||  . . .| |.|.| ||||| .   .| ||...|.|.. .. .| ..|      ..|. ....|...|.|..|||   .    ..| | |. 
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSP

NILL---D---------ENLRARIADFGLSK-LAERGKSYAVTAMRGTPGYMAPEWLH----TKVTDRTDVYSFGIVLLELLS
||||   .         ..  | |||||.|       .. ..  . |.||.|||| .        |. .|.||||..| |||.
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT
Kinase SD2b2_h.AA TK 307-504 16 7.1e-34 110.37 In-house 1-389 (486) Show / Hide 
Range on Protein: 307-504
Range on HMM: 1-389/486
Sequence Identity: 16% (65 aa)

FAKKSMLGEGGFG---MVFKGNLSDG--------------------------TTVAVKRMDVEIEGSNEGQQQ--------------FKAEVLSIGS--I
      |||| ||   .|.|| . ..                          |.|||| .  . . | | ...              . .|     .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHYNLVQLRGFCIHG------------PSSLLVYEYMSNGA----LDKWIF--PKDSRF-----------------------------------------
.| |.|.| | | .|            .  ..| |||..|     |...    ... .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWSQRHQVAVDVARGLAYLHEG----CREQVLHLDIKPQNILLDENLR-----------ARIADFG--
                               |.  |..  ....|.|..|||.        .. | |.   |.|..||..           ..|||||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSKLAERGKSYAVTAMRGTPG-------------------------YMAPEWLHTKV----------TDRTDVYSFGIVLLELLS
      |..  .... | ..  .||..                         .|||| | ..|          |  .||.|||... |...
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD2b2_h.AA Pkinase_Tyr 307-504 29 3.3e-33 113.11 Pfam 1-209 (270) Show / Hide 
Range on Protein: 307-504
Range on HMM: 1-209/270
Sequence Identity: 29% (63 aa)

FAKKSMLGEGGFGMVFKGNLS-----DGTTVAVKRMDVEIEGSNEGQ---QQFKAEVLSIGSI-RHYNLVQLRGFCI-HGPS--SLLVYEYMSNGALDKW
  .  .|||| ||.|.|| .      ....|||| .    ||. . |   . | .|.    .. .| |.|.| | |. .| .   ..| ||| .| |.. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IFPK--DSRFLDWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPG---YMAPE-WLHTKVTD
   .  | . |. ..  | ....|.|..||..       | |.   |.|..||. ..|.||||... .    | ...  |..     |||| . . | | 
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTT

RTDVYSFGIVLLELLS
 .||.|||... |...
KSDVWSFGVLMWEIFT
Kinase SD2b2_h.AA DRK 314-503 36 9.4e-32 104.84 In-house 8-196 (258) Show / Hide 
Range on Protein: 314-503
Range on HMM: 8-196/258
Sequence Identity: 36% (70 aa)

GEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSIRHYNLVQLRGFCIHGPSSLLVYEYMSNGALDKWIFPKDSRFLDWSQRHQVAV
| |..| || |    || ||||..    .   .  . |. |.  .   || | .|  | |   |. . . |||. | | . |   .|  .||. . | . 
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYN-ILHDESIEMDWPLMKQMMF

DVARGLAYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSK--LAERGKSYAVTAMRGTPGYMAPEWLHTKV-TDRTDVYSFGIVLLELL
|.|.|. ||| .|   ..| | |  | | ||. .  .||||||      . .  | |.  |||.  ||| |     |   |||||.||| |..
DCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase SD2b2_h.AA Dicty4-Unclassified 310-503 34 5e-31 103.48 In-house 4-202 (263) Show / Hide 
Range on Protein: 310-503
Range on HMM: 4-202/263
Sequence Identity: 34% (71 aa)

KSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSN-EGQQQFKAEVLSIGSIRHYNLVQLRGFCIHG----PSSLLVYEYMSNGALDKWIF-----PKD
   .|.| |  | |||   |  |||| .         |  | ||.||   ||| | |||...| ||           | | |  | |   |       . 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

SRFLDWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERGKSYAVTAMRGTPGYMAPEWL-HTKVTDRTDVYSFGIV
.  ||      .| |.|.|...||      . | |||  |||.| .  ..|||||.|   .    .  |.  |||   .|| | |   . . ||||....
PIKLDDTLIIKYAFDIAQGMQHLHT---RNFIHRDIKSSNILMDKHFNIKIADFGISRVID--FNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LLELL
| ||.
LYELA
Kinase SD2b2_h.AA STE 307-503 21 7e-30 102.74 In-house 1-262 (359) Show / Hide 
Range on Protein: 307-503
Range on HMM: 1-262/359
Sequence Identity: 21% (57 aa)

FAKKSMLGEGGFGMVFKGNLSD----------------GTTVAVKRMDVEIEGS--------------NEGQQQFKAEVLSIGSIR--HYNLVQLRGFCI
. . ...|.|.|| |.|.   .                |. .|.|.|..| . .              .| .||.. |.      .  | | |.  | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HG-------PSSLLVYEYMSNGALD-----KWIFPKDSR-------FLDWSQRHQVAVDVARG-LAYLHEGCREQVLHLDIKPQNILLDENLRARIADFG
..        .  .. |||..| ||     |.. .|.         ... ||   ..... .| |.|||.     . | ||||.||||     . ..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LSKLAERG-------------KSYA-VT-AMRGTPGYMAPEWLH-------TKVTDRTDVYSFGIVLLELL
...  .               .. .  .  . ||| .|||| .         . . . |..|.|....|..
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase SD2b2_h.AA TyrKc 307-592 19 5e-26 93.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 307-592
Range on HMM: 1-280/280
Sequence Identity: 19% (67 aa)

FAKKSMLGEGGFGMVFKGNLSDGTTVAVKRMDVEIEGSNEGQQQFKAEVLSIGSI--RHYNLVQLRGFCIHG-------PSSLLVYEYMSNGALDKWI-F
  .. .|||| || |.|| ..  ..|||| .  .       .. |  |     ..  .| |.|.| | |...       .  ..| |||..|.|.. .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PKDSRFLDWSQRHQVAVDVARGLAYLHEGCREQVLHLDIKPQNILLDENLRARIADFGLSKLAERG-------KSYAVTAMRGTPG-----YMAPEWL-H
...   | ... .. ....|.| .|||.    .. | |.   |.|..||....|.|||||.  . .       . | ..  .|. .      |||| . .
HRPK--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

TKVTDRTDVYSFGIVL------------------------LELLSSRKSLEIQKH----SSSVASTSGASSSASSQGVFILGHTAARLFHSGDVATLVDR
 | |  .||.|||...                        .|.. ... ... ..    |                                        
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------------

DLEVDLSVAERFAKIGLWCIQEDPAKRPSIGNALAML
         .   .| ..| .|||..||.  .    .
---F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SD2b2_h.AA Dicty4-Unclassified 573-592 40 0.000341 10.22 In-house 244-263 (263) Show / Hide 
Range on Protein: 573-592
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCIQEDPAKRPSIGNALAML
||  .|| |||..      |
WCWHNDPNKRPTMNQIIQYL
Kinase SD2b2_h.AA DRK 574-594 47 0.000601 9.3 In-house 238-258 (258) Show / Hide 
Range on Protein: 574-594
Range on HMM: 238-258/258
Sequence Identity: 47% (10 aa)

CIQEDPAKRPSIGNALAMLEG
|  |||  |||    |  || 
CWNEDPQHRPSMQECLERLEA
Kinase SD2b2_h.AA TK 572-592 28 0.013812 3.63 In-house 466-486 (486) Show / Hide 
Range on Protein: 572-592
Range on HMM: 466-486/486
Sequence Identity: 28% (6 aa)

LWCIQEDPAKRPSIGNALAML
. | ..||..||.    . .|
QQCWHYDPEDRPTFSQLHEQL
Kinase SD2b2_h.AA MLK 574-592 42 0.339143 0.06 In-house 273-291 (291) Show / Hide 
Range on Protein: 574-592
Range on HMM: 273-291/291
Sequence Identity: 42% (8 aa)

CIQEDPAKRPSIGNALAML
| ..||.||||    .  |
CWNQDPHKRPSFRQIVQHL