Gene SD2b2_c-1 (S.moellendorffii)

SD2b2_c-1

Species: S.moellendorffii
Alias: SD2b2_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD2b2

Sequence

Name Sequence Type Origin Length Description Download
SD2b2_c-1.AA Protein None 856 None Fasta, JSON
SD2b2_c-1.NA RNA None 2571 None Fasta, JSON
SD2b2_c-1.kin_dom Protein Kinase Domain None 211 None Fasta, JSON

Protein domain

Protein domains of SD2b2_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin SD2b2_c-1.AA B_lectin 100-201 35 5.7e-33 114.87 Pfam 1-137 (137) Show / Hide 
Range on Protein: 100-201
Range on HMM: 1-137/137
Sequence Identity: 35% (49 aa)

TQRIIWEANRE---DPV-----GLNATLSLAS-DGDLVLRDRD-G-RL--VWST--GTANRG--ATRVEVVRETGNLVVF--RN--NTILWQS--FDRPT
 | . | |||.   .||     . |.||.. . ||.||| | . | .   ||||  .|...|  .  . .  ..||||..   |  |..||||  || ||
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DTLMAGQVLRP------GMR----LQSRRSRT--DPS
||.  |. |.       .|.    | |..| |  |||
DTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin SD2b2_c-1.AA B_lectin 56-175 25 3.8e-20 74.16 SMART 1-126 (126) Show / Hide 
Range on Protein: 56-175
Range on HMM: 1-126/126
Sequence Identity: 25% (34 aa)

QDDYGATTRMTGFFSGV-YNLGFVNSTPDRYTLAVLMNVDSGFPTTQRIIWEA--NREDPVGL---NATLSLASDGDLVLRDRDGRLVWSTGTANRGATR
. . .   .  .. |    .|||.. ..   .. .. .  |.   .....| |  ||. ||     ...|.. ||| ||. |  .| |||..|...    
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ-WCNGIWYKNISNK--QRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNGNY

VEVVRETGNLVVFRNN-----TILWQSFDRP
| |....||.|.....      ..||||| |
VAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
PAN_AP SD2b2_c-1.AA PAN_AP 383-460 18 0.000386 19.16 SMART 1-85 (85) Show / Hide 
Range on Protein: 383-460
Range on HMM: 1-85/85
Sequence Identity: 18% (16 aa)

IESLEFVPVPGVEHFSSKY----VNGSQVTIDECRGRCLRNCSCSAFFFWEESNSCFTVDNTGTLQRVS------TQSHVGYIKATRI
 . . || .|...  .|          .....||. .||.|||| .| . . . .|   .... |....      ..  .|..   ..
CCDDCFVRMPNMKL-FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase SD2b2_c-1.AA TKL 540-805 22 1.2e-61 211.11 In-house 1-364 (364) Show / Hide 
Range on Protein: 540-805
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

LGTGGFGGVYEGTLPD---------GRTVAVKKLEG---TGQGK-------------------------KEFYAEVAVLGSLHHWNLVKLLGFCSEGSN-
.| |||| || |..           |..|||||.         |                         ...  |. .. .|.| |.|...|.| .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEHMTNGSLDKWIYQDSEKNLMVLGWKQRIEIVLGMARGLAYLHEECM-----QRIIHLDIKPQNILLDKSFV-----------
              .|.| . .|||   .            | ||. ..|..|||..||| .         ||| |.|..|||.|. .            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKVADFGLSRLMSRDQSYVMTT------------------MRGTPGYLAPEWLLEA----------------SITEKSDVYSFGVVLLEVISGRKCF
   .|..|||||| ||....  .|                    .|||...||| | ..                . .||.||||||.|| |...... .
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

SRVS-ETEKFYLPSFCLELVQQG-RDMDVVDPRISS-----QADEGEVVRAIRIAFLCLQENASARPSMGSVVQML
.    ....|  | | ..... . . .    | | .     .  .    . ....  | ......|||.  ... |
YDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase SD2b2_c-1.AA Pkinase 534-733 27 5.5e-58 203.74 Pfam 1-209 (293) Show / Hide 
Range on Protein: 534-733
Range on HMM: 1-209/293
Sequence Identity: 27% (59 aa)

GNFSKLLGTGGFGGVYEGTLPDGRT-VAVKKLEGTGQGKKEFYA-----EVAVLGSLHHWNLVKLLGFCSEGSNRLLVYEHMTNG----SLDKWIYQDSE
  . . .| |.|| ||...  . .  ||||...  .. ... ..     |.... .|.| | |.|.... ....  .| |.. .|    .|  .|  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KNLMVLGWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVA----KVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLL-EASITEKSD
.... . ... . ... ..|||.|.|..   .||| |.||.|||.|.  .     |..||||.....   ...|||  |||.|.|||...    .. |.|
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGVVLLEVISGR
..|.|..| |...||
MWSCGCILYEMLCGR
Kinase SD2b2_c-1.AA IRAK 535-743 38 2.4e-52 180.24 In-house 2-232 (317) Show / Hide 
Range on Protein: 535-743
Range on HMM: 2-232/317
Sequence Identity: 38% (89 aa)

NFSKLLGTGGFGGVYEGTLPDGRT--VAVKKLE-----GTGQGKKEFYA---EVAVLGSLHHWNLVKLLGFCSEGSNRLLVYEHMTNGSL-DKWIYQDSE
. . ..| |||| || | . .. |  .|||||       ... ...| .   |. |. ...| |.| |.|.|.|...  |||. |.|||| |    ||  
HKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

KNLMVLGWKQRIEIVLGMARGLAYLHEEC-MQRIIHLDIKPQNILLDKSFVAKVADFGLSRLM---S--RDQSY--VMT-TMRGTPGYLAPEWLL--EAS
  .  | | ||..| .| |.|. .||.      ||| |||. |||||. |..| .|||| |     |   .|.|   || . |||  |..|| .      
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ITEKSDVYSFGVVLLEVISGR-KCFSRVSETE
.| |.||||||.|||||..|.    ....|..
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHY
Kinase SD2b2_c-1.AA TKL-Unique 536-732 31 1.4e-45 157.72 In-house 1-224 (290) Show / Hide 
Range on Protein: 536-732
Range on HMM: 1-224/290
Sequence Identity: 31% (72 aa)

FSKLLGTGGFGGVYEGTLPDGRTVAVKKLE----GTGQGKKEFYAEVAVLGSLH-HWNLVKLLGFCS----EGSNRLLVYEHMTNGSLDKWIYQ-----D
|....|.||.| || |. . |  ||.|...       . ..||. || ..  || | |.|.. |.|       .|. .| | .  |||.. . |      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

SEKNLMVLGWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKS-----FVAKVADFGLSRLMSRD--QSYVMT------TMRGTPGYLAPEWL
  .| . | ..||. ... .|.|. ||| .    |||.|.|..|.|.|       . .|..|||||.. |..   .. .       |  |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LE--ASITEKSDVYSFGVVLLEVISG
    . ..|||||||||.|| | ...
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD2b2_c-1.AA Dicty4 535-728 35 1e-43 143.78 In-house 2-209 (277) Show / Hide 
Range on Protein: 535-728
Range on HMM: 2-209/277
Sequence Identity: 35% (75 aa)

NFSKLLGTGGFGGVYEGTLPDGRTVAVKKLEGTGQGK-----KEFYAEVAVLGSLHHWNLVKLLGFCS----EGSNRLLVYEHMTNGSLDKWIYQ-DSEK
|. ...|.|.|| || ||   |  ||||||  . |.      .|| .||. .... | |.....| |     . .  . | | |  |.| . .    ||.
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

NLMV-LGWKQRIE---IVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSRLMSRDQ--SYVMTTMRGTPGYLAPEWLLEASITEKSD
  .. | |  ..    . .  |||...||. |  .|||.|.|. |.| ||....||.|||||..| ..   .  ..|. |||.. ||| . . . .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGVVLLE
||||| || |
VYSFGIVLWE
Kinase SD2b2_c-1.AA Pkinase_Tyr 535-734 31 2.3e-41 140.72 Pfam 2-213 (270) Show / Hide 
Range on Protein: 535-734
Range on HMM: 2-213/270
Sequence Identity: 31% (69 aa)

NFSKLLGTGGFGGVYEGTLP-----DGRTVAVKKL-EGTGQG---KKEFYAEVAVLGSL-HHWNLVKLLGFCS-EGSN--RLLVYEHMTNGSLDKWIYQD
 | | || | || ||.||.      .. .||||.| ||. .    ...| .|.... .| || |.|.|.| |. .|     ..| |.| .|.|..   . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

SEKNLMVLGWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSRLMSRDQSY-VMTTMRGTPG-YLAPEWLLEASITEKSDV
.  .   |  |. ... .  |.|..||..   ...|| |.   |.|.....|.|..||||.|..  |  | ....    |   .||| . .   |.||||
R-EDKQPLTMKDLLQMCWQIAKGMEYLES---KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YSFGVVLLEVIS-GRK
.||||.. |... |..
WSFGVLMWEIFTYGEQ
Kinase SD2b2_c-1.AA Dicty4-Unclassified 535-732 36 4.2e-41 138.49 In-house 2-204 (263) Show / Hide 
Range on Protein: 535-732
Range on HMM: 2-204/263
Sequence Identity: 36% (76 aa)

NFSKLLGTGGFGGVYEGTLPDGRTVAVKKL-EGTGQGK----KEFYAEVAVLGSLHHWNLVKLLGFCSEG----SNRLLVYEHMTNGSLDKWIY-QDSEK
   . .| | |  |. |    |. |||||. |.  .      ..| .||..|||. | ||||. | |       |    | | |  | |   |  . ||.
QIDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

NLMVLGWKQ--RIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEASITEKSDVYSF
.   .       | . .  |.|...||      .|| |||  |||.|| | .|.||||.||  .  .   |||  |||   .|| |   | . ||||||.
Q-QPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN--MTTIAGTPKWESPECLMHESYNQKSDVYSY

GVVLLEVISG
...| | . |
AMMLYELATG
S_TKc SD2b2_c-1.AA S_TKc 534-805 24 4.5e-41 143.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 534-805
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

GNFSKLLGTGGFGGVYEGTLPD-GRTVAVKKLEGTGQGKKEFYAEVAVLGSLHHWNLVKLLGFCSEGSNRLLVYEHMTN--GSLDKWIYQDSEKNL-MVL
  . ...| |.|| || ..  . || ||.|..       . .. |...| . || |.|||.... . ..  .| |.. .  |.| . | .   . |  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEASITE-KSDVYSFGVVLLE
   .   ..  ....|.|.|.   ..||| |.||.|||||.  . |..||||.|..        ||. ||| |.||| |   . .  |.|..|.|..| |
PE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

VISGRKCFSRVSETEKFYLPSFCLELVQQGRDMDVVDPRISSQADEGEVVRAIRIAFLCLQENASARPSMGSVVQ---------ML
 ..|.  |.   . . | .                                |. .   ||| . . ||.   . |          .
MLCGYPPFP--QMQMMFKKIG---------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD2b2_c-1.AA MLK 534-746 26 2.2e-40 137.85 In-house 1-247 (291) Show / Hide 
Range on Protein: 534-746
Range on HMM: 1-247/291
Sequence Identity: 26% (66 aa)

GNFSKLLGTGGFGGVYEGTLPDGRT-----VAVKKLE-------GTGQGKKEFYAEVAVLGSLHHWN----LVKLLGFCSE-GSNRLLVYEHMTNGSLDK
 .|.. .| |.|| |. |.   ...     ||||. .        |.  ...|  |.  |  | | |     ....| |.. ... ..| | . .|||  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WIYQ---------DSEKNLMVLGWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLD------KSFVAKVADFGLSRLMSRDQSYVMTTMRGTPG
 ..            .||  |    . . . | .|||..|||..  . ||| |.|..|||.|      .  ..|..|||.|| ... .   |. ..||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLAPEWL---LEASITEKSDVYSFGVVLLEVISGRKCFS-RVSETEKFY
. ||| .    .   .||.||.|.|||| |.....  ..  ... . ..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAW
Kinase SD2b2_c-1.AA TK 534-731 17 2.7e-39 128.86 In-house 1-389 (486) Show / Hide 
Range on Protein: 534-731
Range on HMM: 1-389/486
Sequence Identity: 17% (70 aa)

GNFSKLLGTGGFG---GVYEGTLPDGR--------------------------TVAVKKLE-GTGQGKKEFYA-----------------EVAVLGS--L
  . | || | ||    ||.|.. ...                          .|||| |  |... ..|| .                 | ... .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHWNLVKLLGFCSEGSN------------RLLVYEHMTNGS----LDKWIYQDSEKNLM-----------------------------------------
|| |.|.|.| |..| .             ..| |.| .|.    |...  . ..|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------VLGWKQRIEIVLGMARGLAYLHEE----CMQRIIHLDIKPQNILLDKSFV-----------AKVADFG--
                               |  .|.. . .  |.|..|||.       |...| |.   |.|.... |           .|.||||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LSRLMSRDQSYVMTTMRGTPG-------------------------YLAPEWLLEAS---------ITEKSDVYSFGVVLLEVIS
      |.| . .|. |. .. .||..                         ..||| |..            |.||||.||||.. |. .
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD2b2_c-1.AA RIPK 540-737 27 8.9e-37 122.84 In-house 1-229 (290) Show / Hide 
Range on Protein: 540-737
Range on HMM: 1-229/290
Sequence Identity: 27% (64 aa)

LGTGGFGGVYEGTLPDGRTVAVKKL-EGTG-------QGKKEFYAEVAVLGSLHHWNLVKLLGFCSEG-----SN-RLLVYEHMTNGSLDKWIYQDSEKN
.| |||| |.  .  . .....||   .         | ...   |.. . .| . . |...||| .      ..   .| | | |||| .     ... 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

LMVLGWKQRIEIVLGMARGLAYLHEECMQ-RIIHLDIKPQNILLDKSFVAKVADFGLS--RLMSRDQS--------YVMTTMR--GTPGYLAPEWLL--E
   . |. |  ..  ...|  |||  .|.  |||.| ||.|||.|  | .|.|||||.  . .|  ..        | |.     ||  |..|| ..  .
HHPDPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

ASI----TEKSDVYSFGVVLLEVISGRKCFS
..     |.|.|||||..|. || .... ..
KKPIKVVTPKYDVYSFAIVMWEVLTQKHPYE
Kinase SD2b2_c-1.AA LRRK 534-733 23 1.8e-36 126.54 In-house 1-279 (351) Show / Hide 
Range on Protein: 534-733
Range on HMM: 1-279/351
Sequence Identity: 23% (68 aa)

GNFSKLLGTGGFG-GVYEGTLPD---------------------------GRTVAVKKLEGT-------------------------------GQGKKEF
  . ...| ||||  || ... .                           . .||.||.. .                               .... . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YA----EVAVLGSLHHWNLVKLLGFCSEGSNRLLVYEHMTNGSLDKWIYQDSEKNL----MVLGWKQRIEIVLGMARGLAYLHEECMQR--IIHLDIKPQ
.     ||... .|.| |.|.|.||| .   . .| | ...|.|.. .   ..  .     ...|  ...|.|  |.|..|||    ..  ||| | |. 
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSP

NILLDKS------------FVAKVADFGLSRLMSRDQSYVMTTMRGTPGYLAPEWLLEA---SITEKSDVYSFGVVLLEVISGR
|||| .|             .||.||||.||. . ... |  .. |.||..||| . .    . |||.|.||||..| | ....
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase SD2b2_c-1.AA TyrKc 534-805 26 4.7e-35 123.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 534-805
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

GNFSKLLGTGGFGGVYEGTLPDGRTVAVKKLEGTGQGKKEFYAEVAVLGSL--HHWNLVKLLGFCSEG-------SNRLLVYEHMTNGSLDKWIYQDSEK
  . | || | || ||.||.   ..||||.|      ...|. |  .. .|  || |.|.|.| |...          ..| |.| .|.|.. .    .|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

NLMVLGWKQRIEIVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSRLMSRD-------QSYVMTTMRGTPG-----YLAPEWLLEAS
    | .|. ... .  |.| .|||.    ..|| |.   |.|... ...|..||||||    |       . |.... .|. .      .||| . .  
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

ITEKSDVYSFGVVLLEVISGRKCFSRVSETEKFYLPSFCLELVQQG-RDMDVVD--PRISSQADEGEVVRAIRIAFLCLQENASARPSMGSVVQML
 |.||||.||||.. |. .  .      . . .  ..  .|.|.|| | .   .  | .|.   .        |   | .|... ||..  ... .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYP-MSF--VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase SD2b2_c-1.AA DRK 541-730 35 1.8e-32 107.34 In-house 8-196 (258) Show / Hide 
Range on Protein: 541-730
Range on HMM: 8-196/258
Sequence Identity: 35% (70 aa)

GTGGFGGVYEGTLPDGRTVAVKKLEGTGQG----KKEFYAEVAVLGSLHHWNLVKLLGFCSEGSNRLLVYEHMTNGSLDKWIYQDSEKNLMVLGWKQRIE
| |..| |. ||   |  ||||.|           .||  |. ..  | | | .  .| | . .  . . | |  ||| .    .|    . . |  .. 
GRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDES----IEMDWPLMKQ

IVLGMARGLAYLHEECMQRIIHLDIKPQNILLDKSFVAKVADFGLSR--LMSRDQSYVMTTMRGTPGYLAPEWLLEASITEKSDVYSFGVVLLEVI
. .  |.|. |||  |   ||| | |  | | | ..  ||||||||      ...   | || |||.  ||| | .   ||| |||||..|| |..
MMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAM-TMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase SD2b2_c-1.AA DRK 787-807 38 0.000349 10.11 In-house 238-258 (258) Show / Hide 
Range on Protein: 787-807
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CLQENASARPSMGSVVQMLEG
|. |. . ||||  ... || 
CWNEDPQHRPSMQECLERLEA
Kinase SD2b2_c-1.AA TK 787-805 21 0.00116 7.3 In-house 468-486 (486) Show / Hide 
Range on Protein: 787-805
Range on HMM: 468-486/486
Sequence Identity: 21% (4 aa)

CLQENASARPSMGSVVQML
| ..... ||..  ....|
CWHYDPEDRPTFSQLHEQL
Kinase SD2b2_c-1.AA MLK 787-805 36 0.003372 7.1 In-house 273-291 (291) Show / Hide 
Range on Protein: 787-805
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CLQENASARPSMGSVVQML
| ..... |||. ..|| |
CWNQDPHKRPSFRQIVQHL
Kinase SD2b2_c-1.AA LRRK 786-807 27 0.01719 4.61 In-house 330-351 (351) Show / Hide 
Range on Protein: 786-807
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCLQENASARPSMGSVVQMLEG
.| |..   ||.. ..|. |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase SD2b2_c-1.AA Dicty4-Unclassified 787-805 31 0.031295 3.4 In-house 245-263 (263) Show / Hide 
Range on Protein: 787-805
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CLQENASARPSMGSVVQML
|. .    ||.|  ..| |
CWHNDPNKRPTMNQIIQYL
Kinase SD2b2_c-1.AA Dicty4 787-807 30 0.088696 1.91 In-house 255-277 (277) Show / Hide 
Range on Protein: 787-807
Range on HMM: 255-277/277
Sequence Identity: 30% (7 aa)

CLQENASARPSMGSVVQM--LEG
|. .. . |||.  ..|   || 
CWDHDPQHRPSFEEIIQRRILEH
Kinase SD2b2_c-1.AA Pkinase_Tyr 786-805 20 0.281175 4.95 Pfam 251-270 (270) Show / Hide 
Range on Protein: 786-805
Range on HMM: 251-270/270
Sequence Identity: 20% (4 aa)

LCLQENASARPSMGSVVQML
.| ..... ||..  ....|
QCWHYDPEDRPTFSEIHEQL