LZK_a-2

Species: S.moellendorffii
Alias: LZK_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: LZK

Sequence

Name Sequence Type Origin Length Description Download
LZK_a-2.AA Protein None 281 None Fasta, JSON
LZK_a-2.NA RNA None 846 None Fasta, JSON
LZK_a-2.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of LZK_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LZK_a-2.AA TKL 13-270 29 3e-84 286.21 In-house 1-364 (364) Show / Hide
Range on Protein: 13-270
Range on HMM: 1-364/364
Sequence Identity: 29% (108 aa)

LGSGTYGTVYHGKWRG----------TDVAIKRIKA---SCFEGRPVE---------------RDRLILDFWREAG-TLSKLHHPNVVAFYGVVPDGPGG
.|||..|.||.|||||          .|||.|..|    ..|.    |                 . . .| .|    .|.|.|||.| |.|.. ..|.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

T-----------LATVTEYMVNGS-LKQVLQKKDRTIDRRKRLLIATDAAFGMEYLHG--------KNIVHFDLKCENLLVN--MR-------DPHRPV-
.           |. |.||. .|| | ...          .|. .| |.| ||.|||         ..|.| ||| .|.||.  ..       .|  .. 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

CKVGDLGLSKVKRQTM--------------------VSGGVRGTLPWMAPELLSTS--------------SCMVSERVDVFSFGIVMWELLTGEEPYANM
||..|.|||... |..                     .. ..||. |||||.|  .              .   ||..||.|||||.||.||...||...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

HYG---------AIIGGIVSNTLRPPIP------------NWCEPAWRSLMERCWDADPSARPSFAEIASEL
.|          ... ..... ||||||            . | | ...||..|||.||..|||| || ..|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LZK_a-2.AA MLK 7-270 36 2.4e-79 269.91 In-house 1-291 (291) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-291/291
Sequence Identity: 36% (108 aa)

LEEIRELGSGTYGTVYHGKWRGTD-----VAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPN----VVAFYGVVPDGPGGTLATVTEYMVNGSL
... . .|||..| |. |.||..|     ||.||..|. |    .. .  . || .|.  |..| |||    ...||||  . |   .. |.||. .|||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF--DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSL

KQVL-------------QKKDRTIDRRKRLLIATDAAFGMEYLHGKN---IVHFDLKCENLLVN---MRDPHRPVCKVGDLGLSKVKRQT---MVSGGVR
  ||             || ||..|    . .|.. | ||.||| .    |.|.|||  |.|.      | |  ..|. | |.|. . |.   | |   .
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMMS--NA

GTLPWMAPELLST-SSCMVSERVDVFSFGIVMWELLTGEEPYANMHY-GAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASEL
||. ||||| ..   . ..|| .||.|.|.|.||.||.|.||.....  ||. ... | ||||||. | . | .||..||..||. ||||..| ..|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase LZK_a-2.AA Dicty4 7-272 36 5.6e-73 242.76 In-house 1-277 (277) Show / Hide
Range on Protein: 7-272
Range on HMM: 1-277/277
Sequence Identity: 36% (108 aa)

LEEIRELGSGTYGTVYHGKWRGTDVAIKRI---KASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYG--VVPDGPGGTLATVTEYMVNGSLKQVL
.    ..|.| .|.|| |.|||..||.|     .   .|        .. .| .|.  ..|. |||.. |.|    |    |..  |||||  |.|  .|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDE-------NMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL

QK------KDRTID--RRKR-LLIATDAAFGMEYLHGKN--IVHFDLKCENLLVNMRDPHRPVCKVGDLGLSK-VKRQTMVSG---GVRGTLPWMAPELL
 .      .  ..|  ..|| ...| ||| || .||. |  |.| |||  ||||   | .  | ||.|.|||.  |. .. .    .. ||  |||||  
HDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV---DKNWRV-KVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPE--

STSSCMVSER----VDVFSFGIVMWELLTGEEPYA--NMHYGAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASE--LRS
    .|....    .||.||||| ||.||..|||.   | |  .. ....  ||||||.|| | |..|...||| ||. ||||.|| ..  | .
----VMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase LZK_a-2.AA TyrKc 7-270 30 7e-72 246.03 SMART 1-280 (280) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-280/280
Sequence Identity: 30% (92 aa)

LEEIRELGSGTYGTVYHGKWRGTDVAIKRIKASCFEGRPVERDRLILDFWREAGTLSKL--HHPNVVAFYGVVPDGPG-----GTLATVTEYMVNGSLKQ
.. ...||.| .|.||.|.|. ..||.| .|...           . || |||  ..||  ||||.|..|||. .. .     . |  |.||| .|.||.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

VLQKKDRTIDRRKRLLIATDAAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPVCKVGDLGLSKVKRQT--------MVSG----GVR--GTLPWMAPEL
 |.|. ...  .. | .....| |||||| ||..| || . | ||. .     ..|..| |||.             . .     | .    . ||||| 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LSTSSCMVSERVDVFSFGIVMWELLT-GEEPYAN-----MHYGAIIGGIVSNTLRPPIPN-------WCEPAWRSLMERCWDADPSARPSFAEIASEL
.    .. ..  ||.|||..|||..| |..|| .     |    .|  . .   .|. ||        | ..  ..|..||..||. ||.|.|| ...
I--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LZK_a-2.AA Pkinase_Tyr 7-270 32 1.2e-71 243.33 Pfam 1-270 (270) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-270/270
Sequence Identity: 32% (93 aa)

LEEIRELGSGTYGTVYHGKWR------GTDVAIKRIKASCFEG-RPVERDRLILDFWREAGTLSKL-HHPNVVAFYGVVP--DGPGGTLATVTEYMVNGS
.. ...||.| .|.||.|.|.      ...||.| .| .. .         .. || ||| ....| ||||.| .|||.   ..|.  .  |.||| .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN------CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGD

LKQVLQKK---DRTIDRRKRLLIATDAAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPVCKVGDLGLSKVK-----RQTMVSGGVRGTLPWMAPELLST
|.  |.|.   .. ..    | .... | |||||. ||..| || . | ||.    .  |.|..| ||..         . ..|| .   .||||| ...
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT----ENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINY

SSCMVSERVDVFSFGIVMWELLT-GEEP-YANMHYGAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASEL
.    ..  || |||..|||..| ||.| |..|    ..  |  .  | |.|  | .   .|| .||..||. ||.|.|| ..|
GK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase LZK_a-2.AA TKL-Unique 10-270 34 1.9e-70 240.34 In-house 2-290 (290) Show / Hide
Range on Protein: 10-270
Range on HMM: 2-290/290
Sequence Identity: 34% (102 aa)

IRELGSGTYGTVYHGKWRGTDVAIKRIKA-SCFEGRPVERDRLILDFWREAGTLSKLH-HPNVVAFYGVVPD--GPGGTLATVTEYMVNGSLKQVLQ---
.  .|.|.||.||.|||||..||||...  . ..       ... .| .|  ...||| |||.| ..|.  |   . . .  |.||.  |||  ||.   
WNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSN------EMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN

------KKDRTIDRRKRLLIATDAAFGMEYLHGKN--IVHFDLKCENLLVNMRDPHRPVC-KVGDLGLSKVKR--QTMVSG--------GVRGTLPWMAP
      ..  ...  .|. .| |.| ||.||| ..  | |.|||  |.||. . .  ..  |. | ||||..    .| ..        .. |.. ||||
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

ELLSTSSCMVSERVDVFSFGIVMWELLTGEE------PYANMHYGAIIGGIVS--NTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASEL
|.|. . |. || .||.|||||.||..|..       || .|   ...  . .    .|||||| |..  | |...||. ||| |||| || ..|
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase LZK_a-2.AA TK 7-270 19 2.6e-65 217.64 In-house 1-486 (486) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-486/486
Sequence Identity: 19% (97 aa)

LEEIRELGSGTYG---TVYHGKWRG---------------------------TDVAIKRIKASCFEGRPVERDRLILD---------FWREAGTLS--KL
.. ...||.| .|   .|| |.|||                           |.||.| .|. . .    ..|. . |         ...|.  ..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPNVVAFYGVVPDGPG----------GTLATVTEYMVNGS----LKQVLQKKDRT--------------------------------------------
||||.| .|||. .| .          . .  |.||| .|.    |.. |.|....                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IDRRKRLLIATDAAFGMEYLHGK------NIVHFDLKCENLLVNMRDPHR-------PVCKVGDLGLSK
                               .. . .| .. ..| |||||| |      |.|| || . | ||. ... .       ||||..| |||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

VKR-----------QTMVSGGVRGTLP------------------------WMAPELLSTS-------SCMVSERVDVFSFGIVMWELLT-GEEPYAN-M
...              .... ....|                        ||||| | .            ..  ||.|||..|||..| |.|||.  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

H-------------YGAIIGG---------IVSNTLRPPIPNWCE--------------PAWRSLMERCWDADPSARPSFAEIASEL
.             .  .  |          | . .|.| |  |               ...  || .||..||. ||.|... ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LZK_a-2.AA S_TKc 7-273 25 3.3e-59 203.92 SMART 1-231 (231) Show / Hide
Range on Protein: 7-273
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

LEEIRELGSGTYGTVYHGKWRG--TDVAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVN--GSLKQVLQ
 | .|..|.|..|.|| .....    ||||.||                ...||   |.| ||||.| .|.|  |   . |  |.||. .  |.|.....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIK

KKDR-----TIDRRKRLLIATDAAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPVCKVGDLGLSKVKRQTMVSGGVRGTLPWMAPELLSTSSCMVSE-R
|. |      ..      ..   . ..||.| ..|.| ||| ||.|..       . |..| ||...         . ||. .||||.|       .  .
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCK

VDVFSFGIVMWELLTGEEPYANMHYGAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIAS-E-----LRSM
.|. |.|....|.|.|. |.   .. ...  |.             |  ......|.. ||. ||.  |.   |        .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LZK_a-2.AA LRRK 7-272 26 2.6e-58 200.02 In-house 1-351 (351) Show / Hide
Range on Protein: 7-272
Range on HMM: 1-351/351
Sequence Identity: 26% (94 aa)

LEEIRELGSGTYG-TVYHGKWRGTDVAIKRIKASCFEG-------------RPVERDRLILD--------------------------------------
|.. ...|.|..| .|| .||||  |. .|. .. ..               .|  . ...|                                      
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

---FWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVNGSLKQVLQKKDRT--------IDRRKRLLIATDAAFGMEYLHGKN--IVHFDLKCEN
   | .|.  .|.|.|||.|  .|.  . |   |. |.||. .|.| ..|..| ..        |..  .| ||.. | |||||| .|  |.| ||| .|
FREFRHEVWIMSHLNHPNIVSLKGFCIH-P---LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPN

LLV-NMRDPH-------RPVCKVGDLGLSK--VKRQTMVSGGVRGTLPWMAPELLS---TSSCMVSERVDVFSFGIVMWELLTGE-EPYANMH----Y--
 |.  . ..|         ..|..| |.|      .. |  |. |.  ||||| .    ....  .| ||..|||...|||||..  |. ..     .  
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEY--TEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQW

GAIIGGIVSNTLRPPIPNW-CEP-----AWRSLMERCWDADPSARPSFAEIASELRS
  .|  .... |||.||.  | |        .|.. ||..||  ||.| .| . | .
MEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase LZK_a-2.AA Pkinase 7-270 23 2.6e-56 198.21 Pfam 1-293 (293) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-293/293
Sequence Identity: 23% (72 aa)

LEEIRELGSGTYGTVYHGKWRGTD--VAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVNG----SLKQV
.. .| .|||..|.||.....||   ||.|.|| .  |   ... .. |   .|.  . .|.|||.| .|... |  .. .  |.||. .|    .|. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDY

LQ-KKDRTI--DRRKRLLIATDAAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPVC----KVGDLGLSK---VKRQTMVSGGVRGTLPWMAPELLSTSS
.. ......  . .    ...  . |.||.| ..|.| ||| ||.|..     ....    |..| ||.|     ...    .. ||...||||..  ..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDN----NGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIR-GG

CMVSERVDVFSFGIVMWELLTGEEPYANM------HYGAIIGGIVSNTLRPPIPNWCE-------------------PAWRSLMERCWDADPSARPSFAE
 . . .||..|.|....|.|.|. |. .          ..|  | .  |. ..|.||.                   .. ......|.. ||. ||....
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

IASE--L
|     .
ILQHPWF

Kinase LZK_a-2.AA DRK 14-272 36 2.6e-56 189.2 In-house 8-258 (258) Show / Hide
Range on Protein: 14-272
Range on HMM: 8-258/258
Sequence Identity: 36% (96 aa)

GSGTYGTVYHGKWRGTDVAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVNGSLKQVLQKKDRTIDRRKR
| | || |. | |||| ||.|. ..       ..   .. .| ||.  ...| |||.. | |     |      ..|||  ||| ..|      .|   .
GRGNYGEVFRGTWRGTQVAVKMLFNHN-----INDENFLNEFHREINLMCQLRHPNICQFMGTCNNPP--DICICMEYMPRGSLYNILHDESIEMDWPLM

LLIATDAAFGMEYLHGKN--IVHFDLKCENLLVNMRDPHRPVCKVGDLGLSK----VKRQTMVSGGVRGTLPWMAPELLSTSSCMVSERVDVFSFGIVMW
. .. |.| || |||. |  |.| |||  ||||   | |  | || | |||     .| ..     . ||  | ||| |   .    |  ||.||.|| |
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLV---DEHWQV-KVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVL--RNQRYTEKADVYSFAIVLW

ELLTGEEPYANMHYGAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASELRS
|..| . ||. |    ..  .    .|||.| || | .  || .||. ||. |||. |.   | .
ECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase LZK_a-2.AA HH498 7-270 32 5.9e-56 175.71 In-house 1-284 (284) Show / Hide
Range on Protein: 7-270
Range on HMM: 1-284/284
Sequence Identity: 32% (96 aa)

LEEIRELGSGTYGTVYHGKWRGTDVAIKRIKASCFEGRPVE-----RDRLILDFWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVNGSLKQVL
.|  .  ||| .| || |.||.  ||.|| .|. | .   .     .|...    ||.  ...| ||.||.| .   | |   .| ||.|  ||||  .|
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAF-CCKSDSYQWIVDMFC----REVSIMCRLNHPCVVQFVYACCDDP-SQFAIVTQYCDNGSLFSIL

----------------QK-KDRTIDRRKRLLIATDAAFGMEYLHG---KNIVHFDLKCENLLVNMRDPHRPVCKVGDLGLSKVKRQ----TMVS--GGVR
                ||  .| .|   .. |. | | ||.|||    . |.| ||   | |.  .| |    .| | | |  ...    .| .  |  |
NTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-EDGH---AVVADFGESRFVCDMHDDNMTKQPGNLR

GTLPWMAPELLSTS-SCMVSERVDVFSFGIVMWELLTGEEPYANMHYGAIIGGIVSNTLRPPIPNW----CEPAWRSLMERCWDADPSARPSFAEIASEL
    |||||   .| .   |. |||||.....||..|.| |..     |    .     |||||.         | .|. .||.. |. ||.|..|   |
----WMAPEV--FSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL





Kinase LZK_a-2.AA Shk 6-270 36 9.1e-51 174.98 In-house 2-264 (269) Show / Hide
Range on Protein: 6-270
Range on HMM: 2-264/269
Sequence Identity: 36% (103 aa)

DLEEIRELGSGTYGTVYHGKWRGTDVAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYGVVPDGPGGTLATVTEYMVNGSLKQVLQKKD
. |..  ||.| .|.|| |. || .||.|  .   |.           .|  |    ||. |||.. | |     | | .  ||| |  |.|   |  . 
NREDF--LGQGSFGKVYKGRCRGKEVAVKVMHKQNFD------ENTMTSFRKEVHIMSKIFHPNICLFMGACTSQP-GKCMIVTELMPKGNLEKLLHDQM

RTID--RRKR-LLIATDAAFGMEYLHG--KNIVHFDLKCENLLV--NMRDPHRPVCKVGDLGLSK-VKRQTMVSG---GVRGTLPWMAPELLSTSSCMVS
 . .    || .... ||| ||  |||   ||.| |||  ||||  |.|       ||.| |.|.  |. .| .    |  ||  ||||| .        
VKKPFILYKRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWR------VKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNH--PYN

ERVDVFSFGIVMWELLTGEEPYA--NMHYGAIIGGIVSNTLRPPIPNWCEPAWRSLMERCWDADPSARPSFAEIASE--L
| .||.||||. ||.|| .|||      |     .|.   .|||||. | .  . | ..||| .|. ||||.|| ..  |
EKADVYSFGIILWEILTCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRIL

Kinase LZK_a-2.AA CZAK 7-219 35 5.8e-43 149.05 In-house 1-225 (279) Show / Hide
Range on Protein: 7-219
Range on HMM: 1-225/279
Sequence Identity: 35% (81 aa)

LEEIRELGSGTYGTVYHGKWRGTDVAIKRIKASCFEGRPVERDRLILDFWREAGTLSKLHHPNVVAFYGV-VPDGPGGTLATVTEYMVNGSLKQVLQKKD
|.  .. | | .| || . |||.||||| |    |      ..  .  | .| . .||| |||.| | |.   |||      |.|.|  ||| . |  . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENM--FQKEVSIMSKLCHPNCVQFLGACSEDGP-NHHCIVMEWMGGGSLRRLLTDHY

RTIDR--RKRLLIATDAAFGMEYLHG--KN--IVHFDLKCENLLVNMR-DPHRP--------VCKVGDLGLS-KVKRQTMVSGGVRGTLPWMAPELLSTS
  .      .. .| | | || |||.  |   |.| ||   | | .   .|  |        .||. | |||   . |        | |.|||||     
FYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGE

SCMVSERVDVFSFGIVMWELLTGEEPYANM
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NY--TEKVDVYSFGMILWCIITCDQPYQNM

Kinase LZK_a-2.AA CZAK 234-270 42 1.3e-10 34.93 In-house 240-279 (279) Show / Hide
Range on Protein: 234-270
Range on HMM: 240-279/279
Sequence Identity: 42% (17 aa)

RPPIPNWCEPAWR---SLMERCWDADPSARPSFAEIASEL
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RPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL