Gene MLK-p1_d-1 (S.moellendorffii)

MLK-p1_d-1

Species: S.moellendorffii
Alias: MLK-p1_d-1
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-plant1

Sequence

Name Sequence Type Origin Length Description Download
MLK-p1_d-1.AA Protein None 960 None Fasta, JSON
MLK-p1_d-1.NA RNA None 2883 None Fasta, JSON
MLK-p1_d-1.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of MLK-p1_d-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLK-p1_d-1.AA Dicty4 724-936 47 6.7e-109 364.26 In-house 45-277 (277) Show / Hide 
Range on Protein: 724-936
Range on HMM: 45-277/277
Sequence Identity: 47% (111 aa)

FLRKVRLMRRMRHPNVVLFMGAVT----RPPNLSIVTEFLPRGSLFKLIHR------PSNQVD--ERRR-LRMALDVAKGMNYLHSSTPMIVHRDLKSPN
|.. | .|   ||||..||||| |     |. ..||||..|.|.|..|.|       .| . |   ..| .|||.|.|.|||.||...| |.|||||| |
FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHN

LLVDKNWVVKVCDFGLSR-MKHHTFLSS--KSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWH--GMNSMQVVGAVGFQNRRLDIPADM
|||||||.|||||||||. || |. ..   ....||| ||||||....| |||.|||||| .|||..| | |    .|. ||.| ||.    |. ||.. 
LLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWC

DPAIAKIIQECWQNDPALRPTFHEIMDS--LRP
.| ... ||.|| .||  ||.| ||     |  
PPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLK-p1_d-1.AA TKL 668-934 30 2.3e-106 359.65 In-house 1-364 (364) Show / Hide 
Range on Protein: 668-934
Range on HMM: 1-364/364
Sequence Identity: 30% (118 aa)

IGLGSYGEVYRGEWHG----------TEVAIKKFLNQDI----------------SGDALEEFITEVESNHHGKFFFYKAFFFLRKVRLMRRMRHPNVVL
|| |..||||.|.|.|          ..||.|||  ..                 |             . . ..     ||. . ...|.| ||||.|.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYS---------D-M-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQ

FMGAVTRPPN-------------LSIVTEFLPRGSLFKLIHRPSNQVDERRRLRMALDVAKGMNYLHSST------PMIVHRDLKSPNLLVDKNWV----
|||....||.             | ||.|. |.|||. ..|         .|.|.|||.|.|||||||..      | |.||||||.|.|||.||     
FMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSN

----------VKVCDFGLSRMKHHTFLSSKS-------------------QAGTPEWMAPEVLRNE----------------PSNEKSDVYSFGVILWEL
          .|.|||||||...... ....                   | ||| ||||||||..                . .||.||||||..|||.
YMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI

ATLQQPWHGMNSMQVV---------GAVGFQNRRLDIP------------ADMDPAIAKIIQECWQNDPALRPTFHEIMDSL
.| ..|......|...           |.  ..|. ||             |..| ..|..|.||. ||  ||.| ||.. |
LTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLK-p1_d-1.AA DRK 724-936 45 3.5e-96 325.86 In-house 44-258 (258) Show / Hide 
Range on Protein: 724-936
Range on HMM: 44-258/258
Sequence Identity: 45% (99 aa)

FLRKVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPSNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCD
| | . || . ||||...|||. . ||   |..|..||||| .  | .| . |  ....|..|.||||.|||...| |.|||||| ||||| .| ||| |
FHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVAD

FGLSR----MKHHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWQN
||||     .| |.|   .   ||| | |||||||..  || |||||...|||..| | |  ||. .||| .||    |. .|.   |  .. ...||  
FGLSTRFKKHKQHKF--AMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNE

DPALRPTFHEIMDSLRP
||  ||.. |..  |  
DPQHRPSMQECLERLEA
Kinase MLK-p1_d-1.AA TKL-Unique 728-934 38 1.6e-87 297.07 In-house 46-290 (290) Show / Hide 
Range on Protein: 728-934
Range on HMM: 46-290/290
Sequence Identity: 38% (94 aa)

VRLMRRMR-HPNVVLFMGAVT----RPPNLSIVTEFLPRGSLFKLIH---------RPSNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLV
|..| . . |||.|..||. .     |||..||.|..|.||| ...|         ....  .  .|..||.|.|.||.|||.. | | ||||||.|.||
VNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLV

DKN-----WVVKVCDFGLSRMKHHT---FLSSK------SQAGTPEWMAPEVLRN--EPSNEKSDVYSFGVILWELATLQQ------PWHGMNSMQVVGA
| |     | .|.||||||. .      ... .      .  |.. ||||||||.  .  .|||||||||..|||.|| ..      | .||.. |.  .
DNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEM

VGF--QNRRLDIPADMDPAIAKIIQECWQNDPALRPTFHEIMDSL
| .   | |. || .. . . ..||.||  ||  ||.| ||  .|
VHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLK-p1_d-1.AA MLK 728-934 35 1.1e-79 271.07 In-house 56-291 (291) Show / Hide 
Range on Protein: 728-934
Range on HMM: 56-291/291
Sequence Identity: 35% (84 aa)

VRLMRRMRHPN----VVLFMGAVTRPPN-LSIVTEFLPRGSLFKLIHRPSN-------------QVDERRRLRMALDVAKGMNYLHSSTP-MIVHRDLKS
.|. |...|||    .. |.|. ..||. . ||.|... |||. ..|  ..              .|    .. ||..|.||.||||  | .|.||||||
CRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKS

PNLLVD------KNWVVKVCDFGLSRMKHHTFLS-SKSQAGTPEWMAPEVL---RNEPSNEKSDVYSFGVILWELATLQQPWH-GMNSMQVVGAVGFQNR
.|.|.|      .. ..|.||||.||..|..  .   |.|||. ||||||.   |.|. .||.||.|.||.|||. | . | . ....|..   |.  . 
HNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGL

RLDIPADMDPAIAKIIQECWQNDPALRPTFHEIMDSL
|. || . .. ..| ...||. ||. ||.| .|.  |
RPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLK-p1_d-1.AA Shk 728-934 46 4.5e-79 269.0 In-house 47-264 (269) Show / Hide 
Range on Protein: 728-934
Range on HMM: 47-264/269
Sequence Identity: 46% (102 aa)

VRLMRRMRHPNVVLFMGAVT-RPPNLSIVTEFLPRGSLFKLIHRPSNQVD--ERRR-LRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCD
| .| . .|||..||||| |  |  ..||||  |.|.| ||.| .  . .    .| .||..| | ||| ||.| . |.|||||. |||||.||.|||||
VHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILYKRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCD

FGLSR-MKHHTFLSS--KSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWH--GMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWQ
||.|  || |. |.   |...||| ||||||. | | |||.|||||| ||||..| | |      .  . . |.     |  ||.|  .   . || || 
FGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWEILTCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWD

NDPALRPTFHEIMDS--L
 .|  || | ||     |
HNPQRRPSFNEIIQRRIL
Kinase MLK-p1_d-1.AA LRRK 662-936 28 5.3e-71 242.19 In-house 1-351 (351) Show / Hide 
Range on Protein: 662-936
Range on HMM: 1-351/351
Sequence Identity: 28% (106 aa)

LRVGDRIGLGSYG-EVYRGEWHG----------------------------TEVAIKKFLNQ--------DISGDALEEFITEVESNHHG----------
|. .  || |..| .|||..| |                            ..|||||..          .               |  .          
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCN---------------NSNNNNNLNNNNSE

--------KFFFYKAFFFLRK-VRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPS-NQ------V-DERRRLRMALDVAKGMNYLHSS
          .. .||  .|. | .|....|||.|  .|   .|  | .|.|..| |.| ...| .. ..      . .   .|. ||..||||.||||.
QVEDMDQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH

TPMIVHRDLKSPNLLV---D---------KNWVVKVCDFGLSRMKHHTFLS--SKSQAGTPEWMAPEVLR---NEPSNEKSDVYSFGVILWELATLQ-QP
.|.|.|||||||| |.   .          . ..|..|||.|||   .|..   |   |.| |||||..|   .|  .||.|.||||.||||| |.| .|
NPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

WHGMN-------SMQVVGAVGFQNRRLDIPAD-MDP-----AIAKIIQECWQNDPALRPTFHEIMDSLRP
  ...         |.  ..    .|  || . . |        . ||.|||.||  ||.| .| . |  
FDEHDFFDHMQWMEQIEDKI-IEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLK-p1_d-1.AA Pkinase 662-934 24 4.1e-66 230.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 662-934
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

LRVGDRIGLGSYGEVYRGEWHGTE--VAIKKFLNQDISGDALEEFI-TEVESNHHGKFFFYKAFFFLRKVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEF
...| .|| ||.|.||.. ..||.  ||.|..  .... . ... . .                   . ...|.|..|||.| . ......... .|.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEY

LPRG----SLFKLIH-RPSNQV--DERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVV----KVCDFGLSRMK-HHTFLSSKSQAGTPEW
.. |    .|| .|. . .. .  .|.   .... ...|..|.||    |.|||||. |.|.|.| ..    |.|||||.. . .      .. .|||..
CEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

MAPEVLR-NEPSNEKSDVYSFGVILWELATLQQPWHGM------NSMQVVGAVGFQNRRLDIPADMD-------------------PAIAKIIQECWQND
|||||.| ...   |.|..|.|.||.|... . |. |       . ||..  ..    . |.| . .                   ..  ..|  |.. |
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PALRPTFHEIMDS--L
|. |||...|. .  .
PKKRPTAEQILQHPWF
Kinase MLK-p1_d-1.AA TyrKc 662-934 29 2.7e-61 210.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 662-934
Range on HMM: 1-280/280
Sequence Identity: 29% (90 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGDALEEFITEVESNHHGKFFFYKAFFFLRKVRLMRRM--RHPNVVLFMGAVTRP-------PNL
.. |. .| | .||||.|.|  ..||.|.  .                              |.|  |.|..   .|||.| . |..| .       . |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

SIVTEFLPRGSLFKLIHRPSNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHT-FL----SSKSQAG--TPE
 ||.|. | |.| . .... ...  .  | .....|.||.||||    ..||||   | ||..| .||..||||||  ..        . .....     
MIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

------WMAPEVLRNEPSNEKSDVYSFGVILWELATL-QQPWHG-----MNSMQVVGAVGFQNRRLDIPAD--------MDPAIAKIIQECWQNDPALRP
      |||||...    ..||||.|||| .||. |. |||. |     |.  .|.  |  | .|...|..        . ... .|...||. ||. ||
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

TFHEIMDSL
|| || . .
TFSEIHECF
Kinase MLK-p1_d-1.AA Dicty4-Unclassified 724-934 37 3.9e-61 208.13 In-house 45-263 (263) Show / Hide 
Range on Protein: 724-934
Range on HMM: 45-263/263
Sequence Identity: 37% (84 aa)

FLRKVRLMRRMRHPNVVLFMGAVTRP----PNLSIVTEFLPRGSLFKLIH-RPSNQ-----VDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLV
|.. | ..  . ||| |   |.   |      . ||.||...| || .|| .|| |      |.   ...|.|.|.|| .||.    ..|||.|| |.|.
FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILM

DKNWVVKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWHGMN-SMQVVGAVGFQNRRLDIPADMDPAIAKI
||.  .|. |||.||    .|      |||| | .||.|. |  | ||||||....|.||||   |. .    | .   |     |  ||   |. . | 
DKHFNIKIADFGISRVIDFNFNMT-TIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKL

IQECWQNDPALRPTFHEIMDSL
|  || |||  |||. .| . |
IKWCWHNDPNKRPTMNQIIQYL
Kinase MLK-p1_d-1.AA TKL-ciliate2 724-935 38 4.9e-60 198.92 In-house 43-273 (273) Show / Hide 
Range on Protein: 724-935
Range on HMM: 43-273/273
Sequence Identity: 38% (90 aa)

FLRKVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPSNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLK----------------
|.     |  .||||.|.|.|| |. || .|. |.  ||||. |.   . ..    | |.|||.|.|. ||||| | |.|||||                
FVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITL

----SPNLLVDKNWVVKVCDFGLSRMK-HHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIP
    | |.||| |   |. |||  |.|    ..  |   ||  ||||||..     || ||.|...||||.|    |. ..    |   |  .| |  ||
IKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNK--IGTYQWMAPEVIKAFYYTEKADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIP

ADMDPAIAKIIQECWQNDPALRPTFHEIMDSLR
 .  | .| ..| ||.|.  |||.| ||.  | 
KNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase MLK-p1_d-1.AA Pkinase_Tyr 724-934 34 1.6e-59 202.18 Pfam 50-270 (270) Show / Hide 
Range on Protein: 724-934
Range on HMM: 50-270/270
Sequence Identity: 34% (77 aa)

FLRKVRLMRRM-RHPNVVLFMGAVT--RPP-NLSIVTEFLPRGSLFKLIHRP---SNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKN
|.| ...|. . .|||.| ..|..|  . | .. ||.|. | |.| .  ...    ....  . | |....||||.||.|    ..||||   | ||..|
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTEN

WVVKVCDFGLSRMKHHTFLSSKS-QAGT-----PEWMAPEVLRNEPSNEKSDVYSFGVILWELATL-QQP-WHGMNSMQVVGAVGFQNRRLDIPADMDPA
 |||.|||||.|     .  .   ....       |||||....   ..||||.|||| .||. |. .|| . ||   .|. ... ...|...| .  . 
NVVKICDFGLARDI---YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDE

IAKIIQECWQNDPALRPTFHEIMDSL
| .....||. ||. |||| ||   |
IYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLK-p1_d-1.AA S_TKc 662-942 24 3.2e-59 203.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 662-942
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

LRVGDRIGLGSYGEVYRGEWHG--TEVAIKKFLNQDISGDALEEFITEVESNHHGKFFFYKAFFFLRKVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFL
 .... || |..|.||.. ...   .||||.                                 ..| ...... .|||.| . ..     .| .|.|..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYC

PR--GSLFKLIHRPSNQ-----VDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVL
.   |.||..|..   .      .| .  ...  ......|.||    |.|||||  |.|.|.  ..|.|||||.|         ... |||..||||||
DGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL

RNEPSNE-KSDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWQNDPALRPTFHEIMD-SLRPFQRPVI
   . .  |.|..|.|.||.|... . |..  . ...   .|            .|    .|. |.| ||. |||  |..   .   . | .
---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MLK-p1_d-1.AA CZAK 724-934 35 3.3e-52 179.78 In-house 47-279 (279) Show / Hide 
Range on Protein: 724-934
Range on HMM: 47-279/279
Sequence Identity: 35% (82 aa)

FLRKVRLMRRMRHPNVVLFMGAVTRPP--NLSIVTEFLPRGSLFKLIHRPSNQVDE--RRRLRMALDVAKGMNYLHS-STP-MIVHRDLKSPNLLVDKNW
|.. |  |   .|||.| |.|| .       .||.|.   ||| .|    .. .      .. ||.|.|.||||||   .|  |.|||| | | | | . 
FQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSY

V-------------VKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIPAD
               |. |||||| .        .  |   |||||.   |   ||.|||||| |||.. |  ||  .|  |       . | |. .|  
TPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQP

MDPAIA---KIIQECWQNDPALRPTFHEIMDSL
|||      ..|  ||   | .||.| .|.. |
MDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase MLK-p1_d-1.AA Dicty4 662-709 48 1e-18 59.17 In-house 1-50 (277) Show / Hide 
Range on Protein: 662-709
Range on HMM: 1-50/277
Sequence Identity: 48% (24 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKF--LNQDISGDALEEFITEVE
. ...||| ||.||||.| | |.|||.||.  .||. . . |.||  ||.
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVH
Kinase MLK-p1_d-1.AA DRK 662-709 46 1e-15 49.71 In-house 1-49 (258) Show / Hide 
Range on Protein: 662-709
Range on HMM: 1-49/258
Sequence Identity: 46% (23 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDIS-GDALEEFITEVE
  .| ||| |.||||.|| | ||.||.|.  |  |   . | ||  |..
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREIN
Kinase MLK-p1_d-1.AA TKL-Unique 664-708 47 1.6e-14 47.8 In-house 1-46 (290) Show / Hide 
Range on Protein: 664-708
Range on HMM: 1-46/290
Sequence Identity: 47% (22 aa)

VGDRIGLGSYGEVYRGEWHGTEVAIKKFL-NQDISGDALEEFITEV
..  || |.||.||.|.|.|..||||.|  | |.| . ..||. ||
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEV
Kinase MLK-p1_d-1.AA MLK 662-708 23 2.8e-10 31.99 In-house 1-59 (291) Show / Hide 
Range on Protein: 662-708
Range on HMM: 1-59/291
Sequence Identity: 23% (14 aa)

LRVGDRIGLGSYGEVYRGEWHGTE-----VAIKKFL---NQDISG-----DALEEFITEV
...   || ||.|.|..|.|....     ||.|..      |.|      ...|... ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHL
Kinase MLK-p1_d-1.AA CZAK 662-690 51 1.6e-09 30.91 In-house 1-29 (279) Show / Hide 
Range on Protein: 662-690
Range on HMM: 1-29/279
Sequence Identity: 51% (15 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKK
| .|  || | .||||.. | |. ||||.
LKFGQTIGQGFFGEVYKAYWRGKDVAIKI
Kinase MLK-p1_d-1.AA Pkinase_Tyr 662-709 26 1.9e-09 32.64 Pfam 1-55 (270) Show / Hide 
Range on Protein: 662-709
Range on HMM: 1-55/270
Sequence Identity: 26% (15 aa)

LRVGDRIGLGSYGEVYRGEWH------GTEVAIKKFLNQDISGDA--LEEFITEVE
.. |  .| |..||||.|.|.      ...||.|.  ... . ..  .|.|. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAK
Kinase MLK-p1_d-1.AA Dicty4-Unclassified 662-709 32 2.3e-08 24.75 In-house 1-50 (263) Show / Hide 
Range on Protein: 662-709
Range on HMM: 1-50/263
Sequence Identity: 32% (16 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGD--ALEEFITEVE
...   || |   .|..| | | .||.|||     .     ...|  |||
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVE
Kinase MLK-p1_d-1.AA Shk 662-709 35 1e-06 20.49 In-house 1-48 (269) Show / Hide 
Range on Protein: 662-709
Range on HMM: 1-48/269
Sequence Identity: 35% (17 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGDALEEFITEVE
    | .| ||.| || |   | |||.|. . |  .   . .|  ||.
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVH
Kinase MLK-p1_d-1.AA TKL-ciliate2 662-691 40 6e-06 15.22 In-house 1-30 (273) Show / Hide 
Range on Protein: 662-691
Range on HMM: 1-30/273
Sequence Identity: 40% (12 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKF
| .  .|  | || .|.  |  . ||.|||
LEIQNKITEGGYGIIYKAKWREIVVAVKKF