Gene MLKz_g-2 (S.moellendorffii)

MLKz_g-2

Species: S.moellendorffii
Alias: MLKz_g-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLKz

Sequence

Name Sequence Type Origin Length Description Download
MLKz_g-2.AA Protein None 408 None Fasta, JSON
MLKz_g-2.NA RNA None 1227 None Fasta, JSON
MLKz_g-2.kin_dom Protein Kinase Domain None 336 None Fasta, JSON

Protein domain

Protein domains of MLKz_g-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLKz_g-2.AA TKL 63-319 24 5.7e-80 271.99 In-house 1-364 (364) Show / Hide 
Range on Protein: 63-319
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

LGEGAHGKVYEGKYRD----------LSVAVKIIQVGD-TPEDV---------------------AKARSRFVREVAMLSKVQHKNLVKFIG--------
.|.|. |.|| ||.|             ||||.. . .   ..                       ..| ....|. |.|. .| |.|.|.|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-ACEEP------MVLVTELLSGNSLRKYLVNLRPHRMELEQAITFALEIAQVMDCLHANG--------IIHRDLKPDNLLLTAD-------------QKS
 .|..|      . .|.|. .| ||. ||         ..| . .||.||. |. ||...        |||||||..|.|.  .             .  
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKLADFGLAREE----SVTEMMTA----------------ETGTYRWMAPELYSTVTLRNG--------EKKHYNQKVDVYSFAIVLWELLTNRMPFEGM
.|..||||.|.     . . .||.                . ||.||||||.    .  .         ... |..|.|||||.|||||.|| . |....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

SNLQAA---------YAAAFKNVRPSHPE----------SEKLPEELVFILQSCWAEDPSVRPNFAQVVRML
 . .           . .. |. ||  |.           .  |...  ..| ||..||. ||.| ...  |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLKz_g-2.AA TKL-Unique 59-319 31 5.8e-77 262.0 In-house 1-290 (290) Show / Hide 
Range on Protein: 59-319
Range on HMM: 1-290/290
Sequence Identity: 31% (95 aa)

VGSKLGEGAHGKVYEGKYRDLSVAVKIIQVGDTPEDVAKARSRFVREVAMLSKVQ-HKNLVKFIGACE----EPM--VLVTELLSGNSLRKYLV------
...|.|||. |.|| ||.|  .||.|.. .    .   . .  | .||  ..| . |.|.|...|.|      |    .|.| ..|.||...|       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

--NLRPHRMELEQAITFALEIAQVMDCLHANG--IIHRDLKPDNLLLTAD----QKSVKLADFGLAREES-VTEMMTAET---------GTYRWMAPELY
  | . . . ..| ...|. |||.|. || ..  |||||||. |.|.. .    . ..|..||||..  |  ..| . |          |..||||||. 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

STVTLRNGEKKHYNQKVDVYSFAIVLWELLTNRM------PFEGMSNLQAAYAAAF--KNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVRML
. .       ..|..|.|||||.|||||..|.        |..||.  | . ....  .| ||  |..  .|.|.  ..| ||. ||| ||.| ...  |
RMNF------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNH--CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLKz_g-2.AA MLK 57-319 29 3.1e-73 249.61 In-house 1-291 (291) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-291/291
Sequence Identity: 29% (88 aa)

LLVGSKLGEGAHGKVYEGKYRDLS-----VAVKIIQVGDTPEDVAKA---RSRFVREVAMLSKVQHKN----LVKFIGACEEP---MVLVTELLSGNSLR
...  ..|.|. |||. |..|        ||||..   ..  |....   .  | .|.  |....|.|     ..| |.| .|    ..|.| ..| || 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRA-RIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

KYLVNLRP------------HRMELEQAITFALEIAQVMDCLHANG---IIHRDLKPDNLLLTA-----DQKSVKLADFGLAREESVTEM---MTAETGT
 .| . |.             .. ...|...|| .|. |. ||..    |||||||. |.|...     ... .| .|||..|.  ...|   |.   ||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD--WHQMCTNMMSNAGT

YRWMAPELYSTVTLRNGEKKHYNQKVDVYSFAIVLWELLTNRMPFE-GMSNLQAAYAAAFKNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVR
|.|||||  .       .   |. |.||.|...||||.|| ..|.. .......|. .| .. || .| .   || .   .. || .||. ||.|.|.| 
YAWMAPEVIQQ-----FRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST--CPEHWKKLMKQCWNQDPHKRPSFRQIVQ

ML
 |
HL
Kinase MLKz_g-2.AA S_TKc 57-323 25 2.5e-69 237.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 57-323
Range on HMM: 1-231/231
Sequence Identity: 25% (73 aa)

LLVGSKLGEGAHGKVYEGKYRD--LSVAVKIIQVGDTPEDVAKARSRFVREVAMLSKVQHKNLVKFIGACE-EPMVLVTELLSG--NSLRKYLVNLRPHR
  .. |.|.|| |||| .. ..    ||.|||              .. ||...|.| .|.|.||...... . . .|.|...|   .|..|... ..|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG

----MELEQAITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQKSVKLADFGLAREESVTEMMTAETGTYRWMAPELYSTVTLRNGEKKHYNQ-KVDV
    .   .|  .. .|.. .. .| .|||||||||.|.||.     .|..||||||.       |   ||  .||||.            .|.  |.|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL-----------GYGKCKCDW

YSFAIVLWELLTNRMPFEGMSNLQAAYAAAFKNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVR-----MLTAFL
.|. ..|.|.|. . ||.        ... ||...         ..|.  ... |.  ||. ||   .. .     ..  ..
WSCGCILYEMLCGYPPFP-------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MLKz_g-2.AA TyrKc 57-319 28 3.7e-66 227.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-280/280
Sequence Identity: 28% (86 aa)

LLVGSKLGEGAHGKVYEGKYRDLSVAVKIIQVGDTPEDVAKARSRFVREVAMLSKV--QHKNLVKFIGACE---------EPMVLVTELLSGNSLRKYLV
.  | |||||| |.||.|... . |||| .. .         |  | ||  ...|.  .|.|.|...|.|          ||. .|.|. .. .|..|| 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NLRPHRMELEQAITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQKSVKLADFGLAREESVT-------EMMTA-----ET--GTYRWMAPELYSTVT
. ||.   ... . |.. ||. |. || ...|||||   | |.....  || .||||.|.           .. ..     .     .||||||      
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----

LRNGEKKHYNQKVDVYSFAIVLWELLTN-RMPFEG-----MSNLQAAYAAAFKNVRPSHPE-----SEKLPEELVFILQSCWAEDPSVRPNFAQVVRML
     .. .. | ||.|| ...||..|.  .| .|     ||| ..       . .|  |.     .   |.|.  | ..||.|||. ||.|..... .
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLKz_g-2.AA Pkinase 57-319 23 3.8e-61 214.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-293/293
Sequence Identity: 23% (73 aa)

LLVGSKLGEGAHGKVYEGKYRDLS--VAVKIIQVGDTPEDVAKARSRFVREVAMLSKVQHKNLVKFIGACEEP--MVLVTELLSGN----SLRKYLV--N
. .|.|.|.|. |.||... .. .  |||||| . .. ... ... |  .|.... ...|.| |......|..  . .|.|.. |     .|  |.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

LRPHRMELEQAITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQKSV----KLADFGLARE--ESVTEMMTAETGTYRWMAPELYSTVTLRNGEKKHY
 ..  .. .... ....|.. .. .|..|||||||||.|.|.  ..  .    |..|||||.   .   . ||  .||...||||.         . ..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------GGQYY

NQKVDVYSFAIVLWELLTNRMPFEGM---SNLQAAYAAAFKNVRPSHPESEKLP---------------------EELVFILQSCWAEDPSVRPNFAQVV
 .|||..|. ..|.|.|. | || |     |    ..  ... .|  ....  .                     ||.  .. .|.. ||. ||...|..
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

RM--L
    .
QHPWF
Kinase MLKz_g-2.AA TK 57-319 18 3.4e-60 200.16 In-house 1-486 (486) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-486/486
Sequence Identity: 18% (92 aa)

LLVGSKLGEGAHG---KVYEGKYRDL---------------------------SVAVKIIQVGDTPEDVAKARS------------RFVREVAMLS--KV
. .| |||||. |   .||.|..|..                            ||||..  ||. .. ..               ....| .|..  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHKNLVKFIGAC--------------EEPMVLVTELLS-GN---SLRKYLVNLRP---------------------------------------------
.|.|.|...|.|              .||. .|.|. . |.   |||.|| . ||                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------HRMELEQAITFALEIAQVMDCLHAN------GIIHRDLKPDNLLLTADQK----------SVKLADFG---
                             |.. ..| . ... ||. |  ||..      ...||||   | |.. . .           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAREESVTEMMTAETGTYR---------------------------WMAPELYSTVTLRNGE-KKHYNQKVDVYSFAIVLWELLT-NRMPFEG-M
     |||.    .  .. .. ..                           |||||   . . .  | ....  | ||.|| ...||..|  ..|. | |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN--------LQAAYAAA-----------------FKNVRPSHPES---------EKLPEELVFILQSCWAEDPSVRPNFAQVVRML
||        .|  .                    .   .| |  .         .. |||.  ..|.||..||. ||.|.|....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MLKz_g-2.AA Pkinase_Tyr 57-319 30 9.1e-58 196.26 Pfam 1-270 (270) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-270/270
Sequence Identity: 30% (86 aa)

LLVGSKLGEGAHGKVYEGKYR------DLSVAVKIIQVGDTPEDVAKARSRFVREVAMLSKV-QHKNLVKFIGACE---EP--MVLVTELLSGNSLRKYL
.  | |||||| |.||.|...      .. ||||..  | ..|.    |  | ||......  .|.|.|...|.|    ||  . .|.|.  . .|..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

VNL--RPHRMELEQAITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQKSVKLADFGLAREESVTEMM-TAETGTY---RWMAPE--LYSTVTLRNGE
 .    ...  ... . ....||. |. |.....|||||   | |.| .   || .||||||    ..   .. .|.    .|||||   |.        
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-------

KKHYNQKVDVYSFAIVLWELLT-NRMP-FEGMSNLQAAYAAAFKNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVRML
   .. | ||.|| ...||..|  ..| ..|||| .   . . .. |   |  |. |.|.  ....||..||. || |......|
---FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLKz_g-2.AA Dicty4 57-321 31 4.7e-55 182.13 In-house 1-277 (277) Show / Hide 
Range on Protein: 57-321
Range on HMM: 1-277/277
Sequence Identity: 31% (93 aa)

LLVGSKLGEGAHGKVYEGKYRDLSVAVKII---QVGDTPEDVAKARSRFVREVAMLSKVQHKNLVKFIGACE----EP--MVLVTELLSGNSLRKYLVN-
. .....|.|. |.|| |. |   ||||.    ....     ..  . | .||. ..| .| |...| |||     .|  |. |||...  .| . | . 
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFD----ENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDK

--LRPHRMELE-----QAITFALEIAQVMDCLHA-N-GIIHRDLKPDNLLLTADQKSVKLADFGLAR----EESVTEMMTAETGTYRWMAPELYSTVTLR
      . .|.     .|.  |. .|. |  ||. |  |||||||..|||  .. . || .||||..    .|. .  ...  ||  |||||      ..
PSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWR-VKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEV-----MM

NGEKKHYNQKVDVYSFAIVLWELLTNRMPFE--GMSNLQAAYAAAFKNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVRM--LTA
.   . ||.|.|||||.|||||.||   |.   .|.  |.. | . |  ||. | .   |  .   .| || .||..|| |....    | .
H---QPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDW--CPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLKz_g-2.AA LRRK 57-321 25 6.2e-54 185.5 In-house 1-351 (351) Show / Hide 
Range on Protein: 57-321
Range on HMM: 1-351/351
Sequence Identity: 25% (92 aa)

LLVGSKLGEGAHG-KVYEGKYRD----------------------------LSVAVKIIQVG--------------------------DTP----EDVAK
|  ....|.|. | .|| .|.|.                             .||.|.. ..                          | .    || ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

ARSRFVREVAMLSKVQHKNLVKFIGACEEPMVLVTELLSGNSLRKYLVNLRPHR-------MELEQAITFALEIAQVMDCLHANG--IIHRDLKPDNLLL
| . | .||...|. .| |.|. .| | .|. .|.|...  .| ..| | . ..       .     .  ||.||  |. || .   |||||||..| ||
AFREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

-TAD----------QKSVKLADFGLAR-EESVTEM--MTAETGTYRWMAPELYSTVTLRNGEKKHYNQKVDVYSFAIVLWELLTNR-MPFEGMS------
 . .          .  .|.||||. |   ... |      .|. .|||||     ..|.. .. |..|||.|||...|||||| .  ||....      
WSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPE-----IMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQ

-NLQAAYAAAFKNVRPSHPESEKLPE-----ELVFILQSCWAEDPSVRPNFAQVVRMLTA
 . |    .  .  ||. |..   |.     ..   .|.||..||  || | |.|  |  
WMEQIE-DKIIEGLRPTIPQH-YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLKz_g-2.AA UTK 57-319 27 1e-53 182.13 In-house 1-296 (296) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-296/296
Sequence Identity: 27% (84 aa)

LLVGSKLGEGAHGKVYEGKYRD----LSVAVKIIQVGDTPEDVAKARS---RFVREVA---MLSKVQ-HKNLVKFIGAC--EEPMVLVTELLSGNSLRKY
.  | .||.|| | |.......      .... . | .. .|  ...    .| .| .   |..... | |.....| |  |||. .|||. .. .||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LVNLRPHRM------ELEQAITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQ------KSVKLADFG---LAREES---------VTEMMTAE-TGT
| . ||  .       |.| . .|. ||  |  ||  |..||||   | |....        ..|.||||   ..|. .          ... .|   . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

--YRWMAPELYSTVTLRNGEKKHYNQKVDVYSFAIVLWELLTN-RMPFEGMSNLQAAYAAAFKN-VRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQ
   |||||| .   |       .. .| ||.|| .|.||..|. |.|..|||| |.. .   ..  |.  |..   |...  ....||. ||. ||.| .
WPIRWMAPEALTHHT-------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWD--CPHPVYRLMHRCWHYDPQERPDFED

VVRML
.|  .
LVQQM
Kinase MLKz_g-2.AA HH498 57-319 30 2.3e-53 167.36 In-house 1-284 (284) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-284/284
Sequence Identity: 30% (89 aa)

LLVGSKLGEGAHGKVYEGKYRDLSVAVKIIQVGDTPEDVA---KARSRFVREVAMLSKVQHKNLVKFIGAC---EEPMVLVTELLSGNSLRKYL------
.    | | |. |||| |..|   ||||        .        . .|.||| .... .| . |.|..||   .  . .||.  .. ||   |      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

-----VNLRPHR-----MELEQAITFALEIAQVMDCLHA---NGIIHRDLKPDNLLLTADQKSVKLADFGLAR--EESVTEMMTAETGTYRWMAPELYST
      |    .     | |    | ....|. |. ||      ||||||   | |. .| ..|  ||||  |  ..   . ||   |  |||||| .| 
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAV-VADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQ

VTLRNGEKKHYNQKVDVYSFAIVLWELLTNRMPFEGMSNLQAAYAAAFKNVRPSHPES--EKLPEELVFILQSCWAEDPSVRPNFAQVVRML
 .        |  ||||.|.|...||..| ..||       ||   |..  ||  | .   ..|   . ..| ||   |. || |.|.|..|
CQ-------KYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase MLKz_g-2.AA STE 58-314 20 8.9e-53 181.65 In-house 1-350 (359) Show / Hide 
Range on Protein: 58-314
Range on HMM: 1-350/359
Sequence Identity: 20% (74 aa)

LVG-SKLGEGAHGKVYEGKYRDLS-----------------VAVKIIQVGDT-PEDVA------------KARSRFVREVAMLSKVQ--HKNLVKFIGAC
. | .|.|.|| |.|| ..... .                 .|.|.. . .  ..|              . . .. .|. ...| .  |.| ||..|..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

EEP---------MVLVTELLSGNSLRKYLV-NLRP-----------HRMELEQAITFALEIAQV-MDCLHANGIIHRDLKPDNLLLTADQKSVKLADFGL
.             .. |...| ||.. .  .  .           ||.. .| .... .| .  .. || ..|||||.||.| ||      |||.|||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGV

AR--EESVT---------------EMMTAETGTYRWMAPELYS--TVTLRNGEKKHYNQKVDVYSFAIVLWELLTNRMPFEGMSNLQAAYAAAFK-----
.   ..|..               .. .  .||  |||||  .  . . |   .|.|. |.|..|. ....|..| . |.  |....| ....|.     
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R---DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

---------NVRPSHPE-----------------SEKLPEELVFILQSCWAEDPSVRPNFAQ
         .  |. |.                 ..|. .|.   .. |   ||. ||.  |
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase MLKz_g-2.AA Dicty4-Unclassified 57-319 31 1.9e-51 174.46 In-house 1-263 (263) Show / Hide 
Range on Protein: 57-319
Range on HMM: 1-263/263
Sequence Identity: 31% (89 aa)

LLVGSKLGEGAHGKVYEGKYRDLSVAVKIIQVGDTPEDVAKAR----SRFVREVAMLSKVQHKNLVKFIGACEEP------MVLVTELL-SGNSLRKYLV
. .   .|.|.  ||. |  .   ||||..      |   |.|      | .||..|  .|| ||||  |.|  |      |. |.|.. .|| .   ..
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFN-----ENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFE--VI

N----LRPHRMELEQ--AITFALEIAQVMDCLHANGIIHRDLKPDNLLLTADQKSVKLADFGLAREESVTEMMTAETGTYRWMAPELYSTVTLRNGEKKH
.     .   . |.    | .|..||| |  ||   .||||.|  |.|.  .   .| ||||..|. . .  ||.  || .| .||      |. .|   
HSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFN-IKIADFGISRVIDFNFNMTTIAGTPKWESPEC-----LM-HE--S

YNQKVDVYSFAIVLWELLTNRMPFEGMS-NLQAAYAAAFKNVRPSHPESEKLPEELVFILQSCWAEDPSVRPNFAQVVRML
|||| ||||.|..|.||.|   |. .    . ||   . |  ||  |..   .  .      || .||  || . |..  |
YNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDN--CDNFWKKLIKWCWHNDPNKRPTMNQIIQYL