Gene LmjF30.1000 (L.major)

LmjF30.1000

Species: L.major
Alias: LmajK007, LmjF30.1000
External Links:
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF30.1000.AA Protein None 612 None Fasta, JSON
LmjF30.1000.kin_dom Protein Kinase Domain None 410 None Fasta, JSON

Protein domain

Protein domains of LmjF30.1000.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF30.1000.AA AGC 57-368 16 3.1e-46 116.37 In-house 35-333 (395) Show / Hide 
Range on Protein: 57-368
Range on HMM: 35-333/395
Sequence Identity: 16% (67 aa)

VKIVS---KIQVLQQGKVQSVMNE------------KATLQRLAP---------FPYVVR-LYGTAQSEDE--LYFVLEWLP----------HGDLLQHI
.|...   ||. ... .|. .|.|            .  |...            |..|. |. . |..|   ||||.| .|           ..|..|.
MKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHL

R-YVAQERVRQYNEEEAAAGSTASMSSPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALR---CLDFHDIQLITAQ-------LVLALEHT
.                                                                   |   ..|   .. ..|.       .|||||. 
QGR-----------------------------------------------------------------RKEGRFDEERARFYAAEMQKICGCIVLALEYL

AD-RGVVLRD-LKPENVAFDEKYRACLLDFDTADLGGAEN--------------------------MPETNGGVACPPPVDAAAVDEAESSNGGGGDAAA
 . .|.. || |||||. .||.   .| ||  .  |  ..                          .                                 
HSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN---------------------------------

ENGGASSSARRRRRLTVSQ--------IHSMRRRTASFCG--TAHYVSPEMVGECKWSFSSDLWA--LGALVYELVYGEHLFSGMT----------QFEV
       . ......   .        . . | || .|||  |..|..||..     ... | |.  ||.| ||...|   |.| .          ..|.
-------K-CNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEM

LQKVVHGTYV
 ||. .| |.
FQKIMNGRYF
Kinase LmjF30.1000.AA Ciliate-E2 57-435 13 8.1e-36 120.43 In-house 52-365 (365) Show / Hide 
Range on Protein: 57-435
Range on HMM: 52-365/365
Sequence Identity: 13% (63 aa)

VKIVSKIQVLQQGKVQSVM----------NEKATLQRLAPFPYVVRLYGTAQ--SEDELYFVLEWLPHGDLLQHIRYVAQERVRQYNEEEAAAGSTASMS
.||..| |. |. .....|          |||  |..|  .|.....| . |  ... .|.|.| . .|||...|.   . |  . .             
MKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN-HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-------------

SPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALRCLDFHDIQLITAQLVL---------------ALEHTADRG-VVLRDLKPENVAFDEK
                                      . .  ...   |. |..|..                |||.   .. .. ||.||||. |   
--------------------------------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

YRACLLDFDTAD--------------------------------LGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRRRLT
   .. || ..                                 .                                                       
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ-------------------------------------------------------

VSQIHSMRRRTASFCGTAHYVSPEMVGECK---------WSFSSDLWALGALVYELVYGEHLFSGMTQFEVLQKVVHGTYVERQELFPRINFADDADGEA
          . ..|||..|..||...  |         .....|.|.|| . ||...|.. |                                   . 
----IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------------------------------QQ

EQCCGGRRFA-----------------------AVKDFIQR----LLLTDPQKRLGVHPDTHRFDATALRRHALF
... .  .|                         .||.|..    .|  ||.||..        ..  .  |  |
QIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--------GWEQILNHPWF
Kinase LmjF30.1000.AA CAMK 31-415 13 5.7e-26 80.07 In-house 1-414 (425) Show / Hide 
Range on Protein: 31-415
Range on HMM: 1-414/425
Sequence Identity: 13% (72 aa)

PLGSGAISQVVQCRLRCAA----------APLLPVVVKIVSKIQVL-------------------------QQGKVQSVMNEKATLQRLAP------FPY
 ||.|. ..|  |. .                  | .||..| ..                          .. . ..|..| . ...|         | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VVRLYG---------------TAQS-----EDELYFVL---EWLPHG----DLLQHIRYV-------AQERVRQYNEEEAAAGSTASMSSPGTVAGGTTG
...||                | .      ....|.|.   |  . |    ||...|.         .|                               
IIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQ-------------------------------

SAPDGPPVAEASASTGPSKRATAIPASSTALRC--LDFHDIQLITAQLVLALEHTADRGVVLRDLKPENVAFDEK-----------------YRACLLDF
                             . ..  .. .. . .  |.. |...  ....| |||||||. .|..                 .   . ||
--------------------------FDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF

DTA-------------DLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRRRLTVSQIHSMRRRTAS--------FCGTAH
  |             |  |.| | ..             ..                                         | .        |||| .
GFANKFDPGENNFMCSDYKGGE-M-HN-------------QW-----------------------------------------TTPTEGQKMKTFCGTPE

YVS-PEMVGECK--------------WSFSSDLWALGALVYELVYGEHLFSGM-------------TQFEVLQKVVHGTYVERQELFPRINFADDADGEA
|.. ||..  ..               ....| |..| . | .. |.  | |              .. | ..|.  | |    . |. |          
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN--Y----

EQCCGGRRFAA-------------VKDFIQRLLLTDPQKRL
     |  .               .||.|...| .||.||.
-----GPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRM
Kinase LmjF30.1000.AA PDK1 198-363 23 7e-26 75.82 In-house 116-257 (307) Show / Hide 
Range on Protein: 198-363
Range on HMM: 116-257/307
Sequence Identity: 23% (44 aa)

TAQLVLALEHTADRGVVLRDLKPENVAFDEKYRACLLDFDTA---DLGGAE----------NMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGG
.|....||||  ..|.. |||||||.  |.. .  . || ||    .  ..            .                                    
AAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQ------------------------------------

ASSSARRRRRLTVSQIHSMR-------RRTASFCGTAHYVSPEMVGECKWSFSSDLWALGALVYELVYGEHLFSGM-----TQFEVLQKVV
             ..  .|         | .||.||| |||||.  .   . |.|.|||| ..| .| |   | ||     ... ..||..
-------------QHNKGMDKPEEDKQTRCKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIM
S_TKc LmjF30.1000.AA S_TKc 26-425 16 9.1e-25 89.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-425
Range on HMM: 1-231/231
Sequence Identity: 16% (68 aa)

LGTGIPLGSGAISQVVQCRLRCAAAPLLPVVVKIVSKIQVLQQGKVQSVMNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPH--GDLLQHIRYVA
   . ..|.|| ..| .|| .        | .||..          .....| . |..    |..|.||.. |. |.||.|.| ...  |||...|.   
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

QERVRQYNEEEAAAGSTASMSSPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALRCLDFHDIQLITAQLVLALEHTADRGVVLRDLKPENV
 .. |                                                          . ..  ... ...|...|||.  ..|.. |||||||.
RHGLR----------------------------------------------------------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENI

AFDEKYRACLLDFDTADLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRRRLTVSQIHSMRRRTASFCGTAHYVSPEMVG
 .||  .  . ||  | .                                                                   .|||| .|..||.. 
LLDE--HIKICDFGLARQL-----------------------------------------------------------------TTFCGTPWYMAPEVL-

ECKWSF-SSDLWALGALVYELVYGEHLFSGMTQFEVLQKVVHGTYVERQELFPRINFADDADGEAEQCCGGRRFAAVKDFIQRLLLTDPQKRLGVHPDT-
  .... ..| |..| ..||...|. .|.  .......|..                                   .||||...|  ||.||...     
--GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------HRFD
       | . 
DEWDIKCHPWF
Kinase LmjF30.1000.AA Ciliate-E2-Unclassified 56-416 14 1.3e-24 82.36 In-house 28-342 (352) Show / Hide 
Range on Protein: 56-416
Range on HMM: 28-342/352
Sequence Identity: 14% (63 aa)

VVKIVSKIQVLQQGKVQSV---MNEKATLQRL------------------APFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHIRY-----------VA
. |. .|||.  | .....   |||. .....                   | |..|... . |... .|.|.| ...|||.|.|.            . 
AMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFH

QERVRQYNEEEAAAGSTASMSSPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALRCLDFHDIQ--LITAQLVLALEHTADRG-VVLRDLKP
. . |.  .|..|..                                                       ..   ..||....||.    . .. ||.||
NMKQRKIFTEQQAKY-------------------------------------------------------KKAKFYFAQILQGLEYLHHKNNIIHRDIKP

ENVAFDEKY---RACLLDFDTA-----------DLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRRRLTVSQIHSM-RR
||. ||..    . .. ||  .           .                                                      .   ..    . 
ENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQ-----------------------------------------------------Q--QKMQIWKQQ

RTASFCGTAHYV----SPEMVGECKWS----FSSDLWALGALVYELVYGEHLFSGMTQFE--------VLQ----KVVHGTYVERQELFPRIN---FADD
.. .||||  |     .||. .... .    ...| |.|| . ||...|.. |.. .. .        . .    | ..    ...  ||  .   . ..
MMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKH

ADGEAEQCCGGRRFAAVKDFIQRLLLTDPQKRLG
 . ||. ..         |..|..|  .| ||..
WSPEAKDFIN--------DLLQKMLKKNPNKRIT
Kinase LmjF30.1000.AA RSK 197-343 21 6.6e-19 66.0 In-house 109-205 (278) Show / Hide 
Range on Protein: 197-343
Range on HMM: 109-205/278
Sequence Identity: 21% (33 aa)

ITAQLVLALEHTADRGVVLRDLKPENVAFDE---KYRACLLDFDTADLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRR
. |..|||.||  ..|.. |||||||. .|.     .  | ||. . ..                                                   
YMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---------------------------------------------------

RLTVSQIHSMRRRTASFCGTAHYVSPEMVG----ECKWSFSSDLWALGALVYEL
        ..  .| .||.|..|. |||.     ..  . . |.| ||.| ||.
------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEM
Kinase LmjF30.1000.AA MSK 192-343 20 2.3e-17 55.23 In-house 101-203 (277) Show / Hide 
Range on Protein: 192-343
Range on HMM: 101-203/277
Sequence Identity: 20% (32 aa)

HDIQLITAQLVLALEHTADRGVVLRDLKPENVAFDEK---YRACLLDFDTADLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSS
.  . | ..||.|..|  ..|.. |||||||. ||..    .  | ||  | |  ...   ..                                     
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKS------------------------------------

ARRRRRLTVSQIHSMRRRTASFCGTAHYVSPEMVG----ECK-WSFSSDLWALGALVYEL
                     .|.| || .|||.     .    . . |.| ||.. |..
---------------------PCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTM
Pkinase LmjF30.1000.AA Pkinase 26-236 18 2.7e-15 55.15 Pfam 1-156 (293) Show / Hide 
Range on Protein: 26-236
Range on HMM: 1-156/293
Sequence Identity: 18% (42 aa)

LGTGIPLGSGAISQVVQCRLRCAAAPLLPVVVKIVSKIQVLQQGKVQSVM-NEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHG----DLLQHIR
. .| ..|||. ..| .|. .        |.|||..|     . ... .  .| . ..||   |..||||.. ...|..|.|.|....|    ||  .|.
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

YVAQERVRQYNEEEAAAGSTASMSSPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALRCL--DFHDIQLITAQLVLALEHTADRGVVLRDL
                                                                . .|.  . .... .  |.. .||.  ..|.. |||
T--------------------------------------------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL

KPENVAFDEKYRA----CLLDF
||||. .|...      .. ||
KPENILIDNNGHIDACVKICDF
Kinase LmjF30.1000.AA PDK1 57-120 39 5.1e-15 41.95 In-house 33-100 (307) Show / Hide 
Range on Protein: 57-120
Range on HMM: 33-100/307
Sequence Identity: 39% (27 aa)

VKIVSKIQVLQQGKVQSVMNEKATLQRLAP----FPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHIR
.|| .| . . . ||  |  || ....|.     .| .|.||.| |.|  ||||||  |.||||  ..
IKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK
Kinase LmjF30.1000.AA Pkinase 309-435 20 3.4e-14 51.26 Pfam 170-293 (293) Show / Hide 
Range on Protein: 309-435
Range on HMM: 170-293/293
Sequence Identity: 20% (29 aa)

SFCGTAHYVSPEMVG-ECKWSFSSDLWALGALVYELVYGEHLFSGM------TQFEVLQKVVH-GTYVERQELFPRINFADDADGEAEQCCGGRRF----
.|||| .|..|| .    ... ..| |..| ..||.. |. .|.|       .| ...... .  .  ..... .. .|  . . . .     . .    
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTFH

---AAVKDFIQRLLLTDPQKRLGVHPDTHRFDATALRRHALF
    . |||| ..|  ||.||..         |. .  |  |
NWSEECKDFIKWCLCKDPKKRPT---------AEQILQHPWF
Kinase LmjF30.1000.AA AktR 306-346 42 4.3e-12 43.13 In-house 160-201 (268) Show / Hide 
Range on Protein: 306-346
Range on HMM: 160-201/268
Sequence Identity: 42% (18 aa)

RTASFCGTAHYVSPEMVGE-CKWSFSSDLWALGALVYELVYG
.. ||||| .|..|||. .     .|.|.||.|...||.|.|
KAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTG
Kinase LmjF30.1000.AA PKC 304-346 39 7.5e-11 31.23 In-house 154-196 (262) Show / Hide 
Range on Protein: 304-346
Range on HMM: 154-196/262
Sequence Identity: 39% (17 aa)

RRRTASFCGTAHYVSPEMVGECKWSFSSDLWALGALVYELVYG
...|..||||  |..|| . . . ..| | ||.| | ||.  |
GDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAG
Kinase LmjF30.1000.AA Delta 199-352 18 7.6e-11 35.44 In-house 107-202 (259) Show / Hide 
Range on Protein: 199-352
Range on HMM: 107-202/259
Sequence Identity: 18% (29 aa)

AQLVLALEHTADRGVVLRDLKPENVAFDEKYRACLLDFDTADLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRRRRLTVS
. ....|.    .|.. |||| .||  |                                                         |    |     .   
CEIICGLQFLHKKGIIYRDLKLDNVLLDCD-------------------------------------------------------GHIKIA--DFGMCKE

QIHSMRRRTASFCGTAHYVSPEMVGECKWSFSSDLWALGALVYELVYGEHLFSG
..     .. .||||  |..||..   |...| | |. | |.||.. |   |.|
NMYGE-KKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPFHG
Kinase LmjF30.1000.AA MSK 57-130 28 2.6e-10 31.05 In-house 29-106 (277) Show / Hide 
Range on Protein: 57-130
Range on HMM: 29-106/277
Sequence Identity: 28% (22 aa)

VKIVSKIQVLQQGKVQSV-MNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHIR---YVAQERVRQY
.||.||. |.|. |...  . | ..|...   |..| |... |.. ..| |.| .  | |. |||   .   ...|..
MKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMI
Kinase LmjF30.1000.AA PKC 57-119 33 3.2e-10 29.16 In-house 29-91 (262) Show / Hide 
Range on Protein: 57-119
Range on HMM: 29-91/262
Sequence Identity: 33% (21 aa)

VKIVSKIQVLQQGKVQSVMNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHI
.|.. |  ..|   | ..|.||  |   .  |. . |. . |..| |.||.|..  |||  ||
IKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHI
TyrKc LmjF30.1000.AA TyrKc 26-403 13 4.9e-10 -60.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-403
Range on HMM: 1-280/280
Sequence Identity: 13% (57 aa)

LGTGIPLGSGAISQVVQCRLRCAAAPLLPVVVKIVSKIQVLQQGKVQSVMNEKATLQRL-APFPYVVRLYGTAQSE-------DELYFVLEWLPHGDLLQ
.  |  ||.||  .|......      ..| || . .        ..  |.|   . .|    | .||||| . ..       . |. |.|  |||||..
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HIRYVAQERVRQYNEEEAAAGSTASMSSPGTVAGGTTGSAPDGPPVAEASASTGPSKRATAIPASSTALRCLDFHDIQLITAQLVLALEHTADRGVVLRD
..|.   .                                                               |   |   .  |     |. ...... ||
YLRKHRPK---------------------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRD

LKPENVAFDEKYRACLLDFDTADLGGAENMPETNGGVACPPPVDAAAVDEAESSNGGGGDAAAENGGASSSARRR-------RRLTVS-------QIHSM
|   |.  .|..                                                            . .       | ..         .  ..
LAARNCLVGENH------------------------------------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRK

R-RRTASFCGTAHYVSPEMVGECKWSFSSDLWALGALVYELV-YGEHLFSG-----MTQFEVLQKVVHGTYVERQEL-FPRI----NFADDADGEAEQCC
. .. . .       .||   ..| .. || |. | . .|.  ||.   .|     |. .||...| .| . .. .   | .      ..  .   .||.
KEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQ-IMKQCW

GGR-----RFAAVKDFI
        .|.......
HEDPEDRPTFSEIHECF
Kinase LmjF30.1000.AA Delta 57-119 34 5.9e-09 28.5 In-house 29-91 (259) Show / Hide 
Range on Protein: 57-119
Range on HMM: 29-91/259
Sequence Identity: 34% (22 aa)

VKIVSKIQVLQQGKVQSVMNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHI
.| . |  ||.   |.. | |.  |   .  |.. .|. | |....|.||.|.|  |||. ||
IKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHI
Kinase LmjF30.1000.AA AGC 400-435 39 8e-07 12.11 In-house 359-395 (395) Show / Hide 
Range on Protein: 400-435
Range on HMM: 359-395/395
Sequence Identity: 39% (15 aa)

KDFIQRLLLTDPQKRLGVHPDTHRFD--ATALRRHALF
||.|..||  || |||| ....   |  |  ...|  |
KDLIKKLLCKDPEKRLGCGGNDFG-DKGAEEIKNHPWF
Kinase LmjF30.1000.AA RSK 57-120 29 8.2e-07 21.32 In-house 29-93 (278) Show / Hide 
Range on Protein: 57-120
Range on HMM: 29-93/278
Sequence Identity: 29% (19 aa)

VKIVSKIQVLQQGK-VQSVMNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHIR
.|...|  . |  | .  .| |   |.|    | .|.|. . | |..|| ..| .. |.|. |..
MKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQ
Kinase LmjF30.1000.AA AktR 58-120 23 8.5e-07 22.62 In-house 31-93 (268) Show / Hide 
Range on Protein: 58-120
Range on HMM: 31-93/268
Sequence Identity: 23% (15 aa)

KIVSKIQVLQQGKVQSVMNEKATLQRLAPFPYVVRLYGTAQSEDELYFVLEWLPHGDLLQHIR
|...|    .. . . . .|.  .. .. .|  |.|. . |... |.|..|  | |.|.||..
KMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLK
Pkinase_Tyr LmjF30.1000.AA Pkinase_Tyr 26-120 30 3e-06 21.76 Pfam 1-99 (270) Show / Hide 
Range on Protein: 26-120
Range on HMM: 1-99/270
Sequence Identity: 30% (30 aa)

LGTGIPLGSGAISQVVQCRLR-CAAAPLLPVVVKIVSKIQVLQQGKVQSVMNEKATLQRLAPFPYVVRLYGTAQ-SEDE--LYFVLEWLPHGDLLQHIR
.  |  ||.||  .|...... .   . .|| ||..      .| . .. |.| ...  |   | .|||||     ..   .| |.|  |||||| . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
APH LmjF30.1000.AA APH 28-242 11 3.1e-05 18.72 Pfam 1-205 (248) Show / Hide 
Range on Protein: 28-242
Range on HMM: 1-205/248
Sequence Identity: 11% (27 aa)

TGIPLGSGAISQVVQCRLRCAAAPLLPVVVKIVSKIQVLQQGKVQSVMNEKATLQRLAPF-P--YVVRLYGTAQSEDELYFVLEWLPHGDLLQHIRYVA-
.. |...|. .......         ..|... ..         ... .| . |..||.  .  .| |.... . ....... ....  .  .  |  . 
WWRPISGGWSNRTYYRTTDD-R---PRYVLRRYPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLMEWLPGEDLWRW-HA

QERVRQYNEEEAAAGSTASM-SSPGTVAGGTTGSAPDGPPVAEASASTGPS----KRATAIPASSTALRCLDFHD---IQLITAQLVLALEHTAD-RGVV
. . ....  ||.|   | . ...                   . . ....    ... ....   ... ....|   .. . ..|  .|| . . ....
LHCAQRPALLEALARFLARLHQVDPP-----------------DCPFAWWGRWRLYHWRQLMDWCRCWVDPEWFDEDRQWWLWQRLWAWLEAHWPPPCWC

LRDLKPENVAFD--EKYRAC--LLDFDTADLG
 .|..| || .|  .    .  ..|.|.| .|
HGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG
Kinase LmjF30.1000.AA MSK 397-419 52 0.000346 10.05 In-house 248-270 (277) Show / Hide 
Range on Protein: 397-419
Range on HMM: 248-270/277
Sequence Identity: 52% (12 aa)

AAVKDFIQRLLLTDPQKRLGVHP
.. ||.||.||  ||.||||. .
PDAKDLIQWLLTKDPKKRLGMND
Kinase LmjF30.1000.AA PKC 400-435 27 0.000576 8.55 In-house 228-262 (262) Show / Hide 
Range on Protein: 400-435
Range on HMM: 228-262/262
Sequence Identity: 27% (10 aa)

KDFIQRLLLTDPQKRLGVHPDTHRFDATALRRHALF
.. .. ..  .|.||||.||...   . . |.|..|
VSICKGFMTKNPEKRLGCHPQQEE-GEQDIREHPFF
Kinase LmjF30.1000.AA AktR 400-416 61 0.00129 10.29 In-house 236-253 (268) Show / Hide 
Range on Protein: 400-416
Range on HMM: 236-253/268
Sequence Identity: 61% (11 aa)

KDFIQ-RLLLTDPQKRLG
||.|| .||  .|.||||
KDLIQRKLLCKNPNKRLG
Kinase LmjF30.1000.AA RSK 400-435 41 0.001356 9.44 In-house 247-278 (278) Show / Hide 
Range on Protein: 400-435
Range on HMM: 247-278/278
Sequence Identity: 41% (15 aa)

KDFIQRLLLTDPQKRLGVHPDTHRFDATALRRHALF
||.|...|  ||.||||  |.    ||  ...|. |
KDLIRKMLHRDPHKRLGCGPQ----DAEEIKQHPWF
Kinase LmjF30.1000.AA PDK1 399-435 27 0.009749 3.63 In-house 273-307 (307) Show / Hide 
Range on Protein: 399-435
Range on HMM: 273-307/307
Sequence Identity: 27% (10 aa)

VKDFIQRLLLTDPQKRLGVHPDTHRFDATALRRHALF
.|| ...||  || .||.  .    ..  ....|  |
AKDLVKKLLVRDPNDRLTSCDECGGYQ--QIKAHPFF
Kinase LmjF30.1000.AA Delta 400-435 36 0.037249 3.5 In-house 228-259 (259) Show / Hide 
Range on Protein: 400-435
Range on HMM: 228-259/259
Sequence Identity: 36% (13 aa)

KDFIQRLLLTDPQKRLGVHPDTHRFDATALRRHALF
|| ...|.  ||.|||||    ..  .  .|.| .|
KDCLKKLFERDPEKRLGV----QYCPKGDIRQHCFF
Kinase LmjF30.1000.AA AktR 199-222 52 0.05042 4.12 In-house 108-132 (268) Show / Hide 
Range on Protein: 199-222
Range on HMM: 108-132/268
Sequence Identity: 52% (13 aa)

AQLVLALEHTADR-GVVLRDLKPEN
|| .||||.  ..  .. |||||||
AQILLALEYLHQHMNIIYRDLKPEN