Gene LmjF35.1050 (L.major)

LmjF35.1050

Species: L.major
Alias: LmjF35.1050, LmajK018
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Unique

Sequence

Name Sequence Type Origin Length Description Download
LmjF35.1050.AA Protein None 489 None Fasta, JSON
LmjF35.1050.kin_dom Protein Kinase Domain None 308 None Fasta, JSON

Protein domain

Protein domains of LmjF35.1050.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF35.1050.AA CAMK 32-334 22 1.8e-87 281.85 In-house 1-425 (425) Show / Hide 
Range on Protein: 32-334
Range on HMM: 1-425/425
Sequence Identity: 22% (103 aa)

LLGKGGFSEVLAVRHIPTG------------EIRALKVMMRSALV--------------------------GKKGEMVAHEKEILRR-------TCHPAI
 ||.|.|..|  ..|. |.            .  | |.. .. |                           .|. ..| .| ||...         || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLHEAVQ------------TPDK--------VYFAL---NLMNE-----DLFEFIVRN---------------KTVNEGLSRAIMHQLMSGIAYLHEQS
| |.|. .            | .|        .|. .    ..       |||..||..               . ..|   | ...|. |...|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKPENILIN--------VVVKSDAKNAANDDSESVPHVEGLQVMSDINSIPLEQLNVE--------VKIADFGLAKVVME---------------
|||||.||||||..        | . .|                                  |        .||.|||.|.....               
IVHRDLKPENILLDDNNDDSDPV-E-HD----------------------------------EIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEM

---------WDVCSTPCGTSFYIA-PEVIRG-----IEEQGAKPLCTNQRLVKSVDVWSAGVVFYVLLCGRPPFHGQVRT--------GQDRRELLRRID
          . ..|.|||  |.| |||..|      . . |  .....   ...|.||.||. |..|||.||| |  .         |.. .||...| 
HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ-N-A-TDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIM

HGVLFNPNHG------------WDSISAE--------AKNLILKMLDQESSKRITSEEVLRHPFF
 |    | .             ||.|| |        .|.|| |||  . .||.| |..|.||..
KGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF35.1050.AA S_TKc 27-334 26 4.1e-84 286.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-334
Range on HMM: 1-231/231
Sequence Identity: 26% (87 aa)

VNHGKLLGKGGFSEVLAVRHIPTGEIRALKVMMRSALVGKKGEMVAHEKEILRRTCHPAIITLHEAVQTPDKVYFALNLMNE---DLFEFIVRNKT----
   ....|||.|..|  .||. ||.| |.|..          |..  | .||..  || |..|... |. |..|. . ...    |||..|.....    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILINVVVKSDAKNAANDDSESVPHVEGLQVMSDINSIPLEQLNVEVKIADFGLAKVVMEWDVCS
   .|   | .|.|. ....|.|.. |.|||.||||||..                                        ..||.|||||...      .
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------------------------HIKICDFGLARQL------T

TPCGTSFYIAPEVIRGIEEQGAKPLCTNQRLVK-SVDVWSAGVVFYVLLCGRPPFHGQVRTGQDRRELLRRIDHGVLFNPNHGWDSISAEAKNLILKMLD
| ||| .|.||||.                  | ..|.|| |...| .|||.|||.       .  .....|               | |||..| |.|.
TFCGTPWYMAPEVL---------------GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------------SPEAKDFIRKCLQ

QESSKRITSEEVLR-------HPFF
 . .||.|  |.|.       ||.|
KDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF35.1050.AA Pkinase 27-334 28 4.5e-79 273.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-334
Range on HMM: 1-293/293
Sequence Identity: 28% (98 aa)

VNHGKLLGKGGFSEVLAVRHIPTGEIRALKVMMRSALVGKKGEMVAH--EKEILRRTCHPAIITLHEAVQTPDKVYFALNLMNE-----DLFEFIV--RN
   |. .|.|.|..|   .|. ||.| |.|.. ..    .| .  ..  | .|..| .|| |..|.......|..|. . ...      |||..|   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTV--NEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILIN--VVVKSDAKNAANDDSESVPHVEGLQVMSDINSIPLEQLNVEVKIADFGLAKV--VM
...   |   . .| |. .|..|.|...|.|||.|||||||.   ....                                    |||.||||||.    
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-----------------------------------CVKICDFGLAKQFDY-

EWDVCSTPCGTSFYIAPEVIRGIEEQGAKPLCTNQRLVKSVDVWSAGVVFYVLLCGRPPFHGQ--VRTGQDRRELLRRIDHGVLFNPNHGWDSIS-----
    ..|.|||..|.||||||           ..|   ..||.||.|...| .||||||| |.    .  | .....|| .. |  .   |.|||     
NNS-MTTFCGTPWYMAPEVIR-----------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFR

------------AEAKNLILKMLDQESSKRITSEEVLRHPFF
             |.| .| ..|..  .||.| |..| ||.|
HWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF35.1050.AA Ciliate-E2 27-334 21 1.6e-58 199.52 In-house 1-365 (365) Show / Hide 
Range on Protein: 27-334
Range on HMM: 1-365/365
Sequence Identity: 21% (92 aa)

VNHGKLLGKGGFS-----EVLAVRHIP------------------TGEIRALKVMMRS---ALVGKKGEM---------VAHEKEILRRTCHPAIITLHE
 .  |..|.|.|.     .|  |..                    .. | |.|.|. .   ..  .. .|            ||.||..  || || ..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE

AVQ--TPDKVYFALNLMNE-DLFEFIVRNKT-----------VNEGLSRAIMHQLMS---------------GIAYLHEQS-IVHRDIKPENILINVVVK
. |  . ...|. . . .  |||..|  ||.            .|   . || |. .               .. |||..  |.||||||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

SDAKNAANDDSESVPHVEGLQVMSDINSIPLEQLNVEVKIADFGLAKVVMEW--------------------------------DVCSTPCGTSFYIAPE
                                     .||.||||.| . .                                 ..  | |||  | |||
-------------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE

VIRGIEEQGAKPLCTNQRLVKSVDVWSAGVVFYVLLCGRPPFHGQVRTGQDRRELLRRIDHG--VLFNPNH-------------GWDSISAEAKNLILK-
...| ....     . ..  ...|.||.||..| .|.|.|||               .. .   . |....              |...| |.|.|| | 
ILNGKKYDNQ---QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---MLDQESSKRIT-SEEVLRHPFF
   ||. . .||||  |..| ||.|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF35.1050.AA CAMK-Unique 27-334 21 4.8e-54 176.72 In-house 1-363 (363) Show / Hide 
Range on Protein: 27-334
Range on HMM: 1-363/363
Sequence Identity: 21% (85 aa)

VNHGKLLGKGGFSEVLAVRHIPTGEIRALKVMMRSALVGKKGEM------------------VAHEKEILRRTCHPAIITLHEA----VQTPD-------
.  ....|.|.|..|. .  . || ..| |.    .   ||.                       | .|...  || || | .     .....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KVYFALNLMNED-LFEFIVR--------------------NKTVNE--GLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILINVVVK-SDAK
        . |  . . ..  ||. |..                    .   .|   ... || .| | .||.|.|.|||||.|.|||...  .|  .  
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN--

NAANDDSESVPHVEGLQVMSDINSIPLEQLNVEVKIADFGLAKVVMEWDVCS---TPCGTSFYIAPEVI--RGIEEQGAKPLCTNQRLVKSV----DVWS
                         |   .|  .|..||||.. . .  .|.   | |||. |.|||.   ... |     .  .|. .  .    | ||
--------------------HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWS

AGVVFYVLLCGRPPFHGQVRTGQDR------RELLRRIDHGVL-FNPNHGWDS---ISAEAKNLILKMLDQESSKRITSEEVLRHPFF
 ||. | .|||.||| ...    ||       |....|  | .   ..  |..   || |||... . .  . ..|....| | |...
LGVIMYYMLCGCPPFDCEC---EDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase LmjF35.1050.AA Ciliate-E2-Unclassified 28-334 22 3.7e-51 175.69 In-house 2-352 (352) Show / Hide 
Range on Protein: 28-334
Range on HMM: 2-352/352
Sequence Identity: 22% (91 aa)

NHGKLLGKGGFSEVLAVRHIPTGEIRALKVMMRSALVG------KKGEMVAHEKEILRR------------------TCHPAIITLHEAVQTPDKVYFAL
. .| .|.|||..|  ..|. .... |.| |. .  .       |. |..  .||. ..                    || |. .... |. ...|. .
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

NLMNE-DLFEFIVRNKT-----------------VNEGLSR-----AIMHQLMSGIAYLHEQS-IVHRDIKPENILINVVVKSDAKNAANDDSESVPHVE
 ...  ||...|  .|.                 . |  ..      .. |. .|. |||..  |.||||||||||..   |                  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------------------

GLQVMSDINSIPLEQLNVEVKIADFGLAK----------------VVMEWDVCSTPCGTSFYI----APEVIRG--IEEQGAKPLCTNQRLVKSVDVWSA
                | ..||.|||..|                 .   . ..| |||  |.    ||||..|   ... |          ...|.|| 
----------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----------YKCDIWSL

GVVFYVLLCGRPPFHGQVRTGQD-----------RRELLRRIDHGVLFNPNHGW----DSISAEAKNLIL----KMLDQESSKRITSEEVLRHPFF
||..| .| |..|| .. .. ..           | .|.. |  . ...|.. |    . .| |||..|     |||.   .|||| |..| ||.|
GVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF35.1050.AA CAMK1 198-334 37 4.8e-43 122.93 In-house 149-276 (276) Show / Hide 
Range on Protein: 198-334
Range on HMM: 149-276/276
Sequence Identity: 37% (53 aa)

EVK--IADFGLAKVVMEWD-VCSTPCGTSFYIAPEVIRGIEEQGAKPLCTNQRLVKSVDVWSAGVVFYVLLCGRPPFHGQVRTGQD-RRELLRRIDHGVL
..|  ||||||.| . . . . .|.|||  |.||||. ...   .|| .      |..|.||.||..|.|||| |||      . .   ||.. |  . .
KIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPYD------KACDMWSIGVITYILLCGYPPFY-----DENVDNELFEKIKKCEY

FNPNHGWDSISAE-AKNLILKMLDQESSKRITSEEVLRHPFF
  |.  ||.|| . ||..| .||. . .||.| |..|.||..
EFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase LmjF35.1050.AA AGC 199-334 21 1.5e-42 106.63 In-house 194-395 (395) Show / Hide 
Range on Protein: 199-334
Range on HMM: 194-395/395
Sequence Identity: 21% (47 aa)

VKIADFGLAKVVM---------------------------------------------------EWDVCSTPCG--TSFYIAPEVIRGIEEQGAKPLCTN
.|..||||.|..|                                                   . | ..| ||  |  |.|||..              
IKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------------

QRLVKSVDVWS--AGVVFYVLLCGRPPFHGQ------VRTGQDRRELLRRID-------HGVLFNPNH-----GWDSISAEAKNLILKMLDQESSKRIT-
    |..| ||   |...| .|.|.|||.|.           .. |.  .|        ..| |...      .....| |||.|| |.|  . .||.. 
--YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGC

---------SEEVLRHPFF
          ||. .||.|
GGNDFGDKGAEEIKNHPWF
Kinase LmjF35.1050.AA AGC 27-157 25 5.9e-42 105.06 In-house 1-189 (395) Show / Hide 
Range on Protein: 27-157
Range on HMM: 1-189/395
Sequence Identity: 25% (48 aa)

VNHGKLLGKGGFSEVLAVRHI------PTGEIRALKVMMRSA-LVGKKGEMVAHE---------------KEILRRTC----------HPAIIT-LHEAV
 .  |..|||.|..|  ||.        ||.. |.||.  .   | ||  ||.|                ..|| .            || |.  || . 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPDK--VYFALNLMN----------E-DLFEFIV---RNKTVNEGLSRAIMHQ-------LMSGIAYLHE-QSIVHRD-IKPENILIN
|..|.  .|| . .|.            .||  .    .... .|  .| .. .       . ... |||. . |.||| .||||||..
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLD
Kinase LmjF35.1050.AA RAD53 25-157 34 2.1e-34 99.49 In-house 1-143 (305) Show / Hide 
Range on Protein: 25-157
Range on HMM: 1-143/305
Sequence Identity: 34% (50 aa)

YDVNHGKLLGKGGFSEVLAVRHIPTGE------IRALKVMMRSALVGKKGEMVAHEKEILRRTCHPAIITLHEAVQTP-DKVYFALNLMNE-DLFEFIVR
|...  | ||.|.|..|. .    |..      | . |  .|.  . || . |  | |||..  || || ... ..|| . .|. | ||.  .||..|| 
YYMS--KELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVS

NKT----VNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILIN
||.    ..|  ....  |.  .. |||.. |.|||.||||||.|
NKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCN
Kinase LmjF35.1050.AA DCAMKL 25-157 31 4.3e-34 103.04 In-house 1-149 (279) Show / Hide 
Range on Protein: 25-157
Range on HMM: 1-149/279
Sequence Identity: 31% (48 aa)

YDVNHGKLLGKGGFSEVLAVRHIPTG-EIRALKV-----------------MMRSALVGKKGEMVAHEKEILRRTCHPAIITLHEAVQTPDKVYFALNLM
|..  |.. |.| |. |  .||  || .  |.|.                   .... ||   |.  | .|...  || || |.|.. |... |  . . 
YQI--GRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKE-HMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYV

NE-DLFEFIVRNKTVNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILIN
   |||. |. |  . |  ....|..| . . |||| .|||||||||| |..
QGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVC
Kinase LmjF35.1050.AA CAMK1 25-155 33 5e-34 96.27 In-house 1-140 (276) Show / Hide 
Range on Protein: 25-155
Range on HMM: 1-140/276
Sequence Identity: 33% (48 aa)

YDVNHGKLLGKGGFSEVLAVRHIPT---GEIRALKVMM-RSALVGKKG---EMVAHEKEILRRT---CHPAIITLHEAVQTPDKVYFALNLMNE-DLFEF
| .  || .|.| ||||  . |. |   |.  |.|..  .... .|.    |..  | ||...     || || ..|  ......|. ..|..  .||. 
YEF--GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

IVRNKTVNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENIL
|| ..  .|   | ||.|. | . |.|.. |||||.||||.|
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL
Kinase LmjF35.1050.AA RAD53 199-334 38 7.6e-34 97.8 In-house 166-305 (305) Show / Hide 
Range on Protein: 199-334
Range on HMM: 166-305/305
Sequence Identity: 38% (58 aa)

VKIADFGLAKVVMEWDVCSTPCGTSFYIAPEVIR--------GIEEQGAKPLCTNQRLV---KSVDVWSAGVVFYVLLCGRPPFHGQVRTGQ--DRRELL
.||.||||.|.| |  .  | |||  | |||||.        . ||   .        |   |.||.||.|.. |..|||.|||   .  .|    . | 
IKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITSKGHNCYHENEERQVQ--------VGYTKKVDCWSMGCILYICLCGYPPF--SDDYTQEMHCMQLF

RRIDH-GVLFNPNHGWDSISAEAKNLILKMLDQESSKRITSEEVLRHPFF
  |   | .. |   ||.|| |||.|| .||  .  ||.| .|.|.|| .
EQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM
Kinase LmjF35.1050.AA RSK 198-334 33 2.1e-32 113.97 In-house 145-278 (278) Show / Hide 
Range on Protein: 198-334
Range on HMM: 145-278/278
Sequence Identity: 33% (50 aa)

EVKIADFGLAKV-VME-WDVCSTPCGTSFYIAPEVIRGIEEQGAKPLCTNQR-LVKSVDVWSAGVVFYVLLCGRPPFHG--QVRTGQDRRELLRRIDHGV
..|. |||..|  . .      |.|.|  |.|||...  . |        |.   |..|.|| ||. | .| |.|||.|  .    ..| |...|| .| 
HIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-Q--------QGGHDKACDWWSLGVLMYEMLTGCPPFQGPND----NNRKEIMKRIQKGK

LFNPNHG-WDSISAEAKNLILKMLDQESSKRIT-----SEEVLRHPFF
 |..... |...|.|||.|| |||  . .||..      ||...||.|
-FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase LmjF35.1050.AA CAMKL 27-156 30 8.3e-30 92.18 In-house 1-160 (297) Show / Hide 
Range on Protein: 27-156
Range on HMM: 1-160/297
Sequence Identity: 30% (49 aa)

VNHGKLLGKGGFSEVLAVRH-IPTGEIRALKVMMRSALVGKKGEM-------------VAHEKEILRRTC---HPAIITLHEAVQTPDK------VYFAL
 . || ||||.|..|   .| . |||  | |.. .. .  .   .             .  | .|...     || || |.| ..||..      .|  .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

NLM--NE-DLFEFIVRN----KTVNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILI
 .    | |||..||..    .   |.  | .  |..|...|.|.. ||||||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILL
Kinase LmjF35.1050.AA CAMKL 199-334 27 2.7e-27 84.03 In-house 168-297 (297) Show / Hide 
Range on Protein: 199-334
Range on HMM: 168-297/297
Sequence Identity: 27% (40 aa)

VKIADFGLAKVVME-----WDVCSTPCGTSFYIAPEVIRG-IEEQGAKPLCTNQRLVKSVDVWSAGVVFYVLLCGRPPFHGQVRT--GQDRRELLRRIDH
.||.|||..   ..      . ..| ||.  | |||.. |  ..  ...          ||.||.||. |...||. || ..     |.|   .|.... 
IKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPK----------VDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIM

GVLFNPNHGWDSISAEAKNLILKMLDQESSKRITSEEVLRHPFF
.  ..|.. | ..| ....|| |||    .||.| .....||..
CG-YYPPI-WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase LmjF35.1050.AA DCAMKL 252-334 43 2e-24 72.4 In-house 200-279 (279) Show / Hide 
Range on Protein: 252-334
Range on HMM: 200-279/279
Sequence Identity: 43% (36 aa)

VDVWSAGVVFYVLLCGRPPFHGQVRTGQDRRELLRRIDHGVLFNPNHGWDSISAEAKNLILKMLDQESSKRITSEEVLRHPFF
||.|.|||. |.|||| ||| ..   ..|  ||   |  | .  |   || ||. ||.|| .||  .  || |.|... ||  
VDIWAAGVILYILLCGFPPFRSP---DNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase LmjF35.1050.AA RSK 30-157 34 8.4e-24 84.09 In-house 1-138 (278) Show / Hide 
Range on Protein: 30-157
Range on HMM: 1-138/278
Sequence Identity: 34% (47 aa)

GKLLGKGGFSEVLAVRHI---PTGEIRALKVMMRSALVGKK--GEMVAHEKEILRRTC-HPAIITLHEAVQTPDKVYFALNLMN-EDLFEFIVRNKT---
 |.||.||. .|  .| .    || | | ||  .. .| ..   . .  | .|| |.  || |.|||.| ||..|.|  . ...  .||. . . |.   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

VNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILIN
  |   ...| .. . . .||.| |.|||.|||||| .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYD
Kinase LmjF35.1050.AA DCAMKL 197-232 40 1.7e-10 28.3 In-house 156-192 (279) Show / Hide 
Range on Protein: 197-232
Range on HMM: 156-192/279
Sequence Identity: 40% (15 aa)

VEVKIADFGLAKVVME-WDVCSTPCGTSFYIAPEVIR
...| .|||||..| . . . .| |||  |.|||...
KSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM
Kinase LmjF35.1050.AA TyrKc 27-334 18 5.9e-10 -61.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-334
Range on HMM: 1-280/280
Sequence Identity: 18% (63 aa)

VNHGKLLGKGGFSEVLAVRHIPTGEIRALKVMMRSALVGKKGEMVAHEKEILRRT--CHPAIITLHEAVQTP-------DKVYFALNLM-NEDLFEFIVR
.  || || | | ||   . .   .  | |..  .|      |.  .| .|...    || |. |. .. ..       . ..  . .| . || ... .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NKT-VNEGLSRAIMHQLMSGIAYLHEQSIVHRDIKPENILINVVVKSDAKNAANDDSESVPHVEGLQVMSDINSIPLEQLNVEVKIADFGLAKVVMEW--
..  ..      ...|  .| .|||.. ..|||.   |.|..                                         |||.||||.. . .   
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------------------TVKISDFGLSRDIYDDDQ

-----DVCST---PCGTS----FYIAPEVIRGIEEQGAKPLCTNQRLVKSVDVWSAGVVFY-VLLCGRPPFHGQVRTGQDRRELLRRIDHG-VLFNPNHG
     |. ..    .| .       |||.|        .  .| .      |||| ||. . ..  | .|  |..    . .|.......|  .  | ..
QGESKDYYRKKEHKGGKTMLPIRWMAPECI-------NYGKFTTK-----SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPND

WDS-----ISAEAKNLILKMLDQESSKRITSEEVLRHPFF
         ..|  .....  . . ..| | .|.  | .|
Y-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF