Gene LmjF35.0490 (L.major)
LmjF35.0490
Species: L.major
Alias: LmjF35.0490, LmajK029
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF35.0490.AA | Protein | None | 1677 | None | Fasta, JSON |
| LmjF35.0490.kin_dom | Protein Kinase Domain | None | 755 | None | Fasta, JSON |
Protein domains of LmjF35.0490.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | LmjF35.0490.AA | S_TKc | 25-779 | 9 | 3.6e-53 | 183.89 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 25-779
Range on HMM: 1-231/231
Sequence Identity: 9% (76 aa)
YVVGHRLGEGAYGSVYVVKYLPSGDRFALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISEAMVMQALEHP
| .. .|.||.|.|| .. .| ..|.||. ..|..| ... ||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------------------------------EHIRREIQILKK-HHP
HVVKFYKFLNSTTAFYFVMELAEG--GKLLDLILSKSY------FAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDGRLLVCDFGFSSKIAK
..||.| . . . .|.|||...| | |.|.| .. . | | .|| |..|...|..|||..|. | ||| ||.||.. .. .||||.. ..
NIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--
ENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWSSFSTSSSSASHTSSC
----------------------------------------------------------------------------------------------------
SGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLASATNSHKH
----------------------------------------------------------------------------------------------------
KWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSAAHQPLRH
----------------------------------------------------------------------------------------------------
LRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDADVGEFGP
----------------------------------------------------------------------------------------------------
PVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILGTSTPCKS-------QLIIVDPFQQDLWSAGV
.| | . | ... | || |.
----------------------------------------------------------------------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGC
ILFFMLTGRLPFEGRDEEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQIIA-------NPWF
||. ||.|. ||. ........| || |. .. ..| .|..|||. .. . |||
ILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||
| Kinase | LmjF35.0490.AA | AGC | 25-690 | 6 | 9.4e-51 | 128.34 | In-house | 1-266 (395) | Show / Hide |
Range on Protein: 25-690
Range on HMM: 1-266/395
Sequence Identity: 6% (51 aa)
YVVGHRLGEGAYGSVYVVKYL------PSGDRFALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISE----
. . .|.|..| || |. .|. .|.|.|.|.. . . | ......|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKH--------------------------------------KIVIKKKNMVEHTMTEHWKQ
--------AMVMQALE----------HPHVVK-FYKFLNSTTA--FYFVMELAE---------GG-KLLDLIL---SKSYFAEDEARMYFQQ-------L
... . || .|| . . . |||||... || |. . . .| |..|| |. . .
DQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCI
ISAIDYCHR-NGVAHKD-LKAENLLLSDDGRLLVCDFGFSSKIAKEN--------------------------------------IDDPEQTIGTGGNAA
..|..| |. .|. | | || ||.|| .|| . .|||.. .. ... .
VLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMS-------------
LLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWSSFSTSSSSASHTSSCSGSLARGWRRKAAEVVS
----------------------------------------------------------------------------------------------------
SKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLASATNSHKHKWVSPTSGLNKVGEGLS
----------------------------------------------------------------------------------------------------
ILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSAAHQPLRHLRTNAPSQARVPSPSSG
----------------------------------------------------------------------------------------------------
MSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDADVGEFGPPVTAFDRDAVGAPPLPL
----------------------------------------------------------------------------------------------------
PVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILG----TSTPC
| ... . . |.| |
----------------------------------------Q--E-DDTTR-KKRDRTWTFC
|
|||||||||
| Kinase | LmjF35.0490.AA | CAMKL | 25-693 | 8 | 1e-50 | 160.01 | In-house | 1-193 (297) | Show / Hide |
Range on Protein: 25-693
Range on HMM: 1-193/297
Sequence Identity: 8% (59 aa)
YVVGHRLGEGAYGSVYVVKY-LPSGDRFALKILQKQDLFT-------SSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISEAM
| .| ||.|..| | . . | . | ||. |. . | .. . | |.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG--------------------------------QKH---ESDM-RIRREIQ
VMQALE---HPHVVKFYKFLNSTTA------FYFVMELAEGGK--LLDLILSKSY----FAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDG
|. | ||...|.| . . .| |||...|| |.| | .. . . |.||| ||.|..||..|||..|..| |.|.||.||...|
IMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENG
--RLLVCDFGFSSKIA-KENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTAT
. ..||||| .. .
NNNIKIIDFGFSNMYRPC----------------------------------------------------------------------------------
PWSSFSTSSSSASHTSSCSGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSL
----------------------------------------------------------------------------------------------------
HRAGSTHSLASATNSHKHKWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFS
----------------------------------------------------------------------------------------------------
VGGEAEEGPSAAHQPLRHLRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRP
----------------------------------------------------------------------------------------------------
GTKDGGAVSDADVGEFGPPVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILGTSTPCKSQ
| |. .| .
------------------------------------------------------------------------------------IFGPGQKLKTF
|
|||||||||
| Kinase | LmjF35.0490.AA | CAMK | 30-689 | 7 | 2.2e-50 | 160.16 | In-house | 1-270 (425) | Show / Hide |
Range on Protein: 30-689
Range on HMM: 1-270/425
Sequence Identity: 7% (55 aa)
RLGEGAYGSVYVVKYLPSG------------DRFALKILQKQDLFT-------SSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTF---
||.|..| |. .. .. ..| ||. |. | . .. .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSN------------------------------C-Y-KIDKSKCKHRYC
------EQQIISEAMVMQA-------LEHPHVVKFYKFLNS-------------------TTAFYFVM---ELAEGG----KLLDLILSKSY--------
.... .| .|. | ||...|.| . . .. .|.|| |...|| |.| | ....
WRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQF
-------FAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDD-----------------GRLLVCDFGFSSKIAKEN----------------ID
| |.||| ||.|..||..||| ....| ||| ||.||.|. . . ..||||. |. . . .
DIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW-
DPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWSSFSTSSSSASHTSSCSGSL
----------------------------------------------------------------------------------------------------
ARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLASATNSHKHKWVS
----------------------------------------------------------------------------------------------------
PTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSAAHQPLRHLRTN
----------------------------------------------------------------------------------------------------
APSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDADVGEFGPPVTA
----------------------------------------------------------------------------------------------------
FDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILGTSTP
.||
------------------------------------------------------------------TTP
|
|||||||||
| Kinase | LmjF35.0490.AA | CAMK1 | 25-690 | 8 | 2.6e-44 | 126.7 | In-house | 1-174 (276) | Show / Hide |
Range on Protein: 25-690
Range on HMM: 1-174/276
Sequence Identity: 8% (58 aa)
YVVGHRLGEGAYGSVYVVKYLPS---GDRFALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFE---QQIISEAMVM
|..| ..|.|| . || .. . |. .|.|.. | ...| . ... | .|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-----------------------------------------KKFMKKKDMQKQEALENEIEIM
Q---ALEHPHVVKFYKFLNSTTAFYFVMELAEGGKLLDLILSKSYFAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDD--GRLLV---CDFGF
. . ||...||| . |.. ||.|||| || |.| |. | .. |..|| .|..||. |.| .|..| ||| ||||..| . .. .|||
KKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGL
SSKIA-KENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWSSFSTSSSS
| .. .||
SKIFDHDEN-------------------------------------------------------------------------------------------
ASHTSSCSGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLAS
----------------------------------------------------------------------------------------------------
ATNSHKHKWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSA
----------------------------------------------------------------------------------------------------
AHQPLRHLRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDA
----------------------------------------------------------------------------------------------------
DVGEFGPPVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILGTSTPC
.|.|
---------------------------------------------------------------------------LMKTAC
|
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| Kinase | LmjF35.0490.AA | Pkinase | 25-253 | 23 | 3.1e-41 | 146.86 | Pfam | 1-181 (293) | Show / Hide |
Range on Protein: 25-253 Range on HMM: 1-181/293 Sequence Identity: 23% (56 aa) YVVGHRLGEGAYGSVYVVKYLPSGDRFALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISEAMVMQALEHP |..| ..|.|..|.|| . .|...|.||. |.. . .. . ||. .|. | || YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----------------------------------------SEIQIMKRLNHP HVVKFYKFLNSTTAFYFVMELAEGG----KLLDLIL--SKSYF--AEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDGRL----LVCDFGFSS ..|..| . . . |.|||..||| | |.| .. | |.|...|. |......|||..|. | ||| ||.|....| . .||||.. NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK KIAKENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPE .. . . . ||..| .|| QFD------------------Y-NNS-MTTFCGTPWYMAPE |
|||||||||
| Kinase | LmjF35.0490.AA | MARK | 109-690 | 6 | 2.5e-40 | 129.63 | In-house | 44-166 (262) | Show / Hide |
Range on Protein: 109-690
Range on HMM: 44-166/262
Sequence Identity: 6% (41 aa)
QQIISEAMVMQALEHPHVVKFYKFLN--STTA-FYFVMELAEGGKLLDLILSK--SYFAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDG--
. . .|. .|. |.||...|... .. .|..||.|.|| |.| | .. . |.||| .|.|..||. |||.....| |.|.||.|. ..|
KNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNH
RLLVCDFGFSSKIAKENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAFVGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWS
.||||| .| ..
NIKIIDFGFSICIPPGQK----------------------------------------------------------------------------------
SFSTSSSSASHTSSCSGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRA
----------------------------------------------------------------------------------------------------
GSTHSLASATNSHKHKWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGG
----------------------------------------------------------------------------------------------------
EAEEGPSAAHQPLRHLRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTK
----------------------------------------------------------------------------------------------------
DGGAVSDADVGEFGPPVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQPRSNSSSQILGTSTPC
.| |
------------------------------------------------------------------------------------LNTFC
|
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| Kinase | LmjF35.0490.AA | AMPK | 111-211 | 39 | 4.2e-39 | 113.79 | In-house | 46-147 (254) | Show / Hide |
Range on Protein: 111-211 Range on HMM: 46-147/254 Sequence Identity: 39% (40 aa) IISEAMVMQALEHPHVVKFYKFL-NSTTAFYFVMELAEGGKLLDLILSKSYFAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDGRLLVCDFG | .| .. . |||... | . ..| .. ||| . || | | | .. |.||. .||| ||...||||....| ||| ||||| .. .. . ||| IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFG FS | LS |
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| Kinase | LmjF35.0490.AA | Ciliate-E2-Unclassified | 25-686 | 6 | 6.2e-38 | 129.17 | In-house | 1-225 (352) | Show / Hide |
Range on Protein: 25-686
Range on HMM: 1-225/352
Sequence Identity: 6% (46 aa)
YVVGHRLGEGAYGSVYVVKYLPSGDRF----------------------------ALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAP
| ... .|.|..|.|| .. . . ......| . . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-K-------------------------------
VPTVAALAKTFEQQIISEAMVMQA----LEHPHVVKFYKFLNSTTAFYFVMELAEGGKLLDLILSKSY-----------------FAEDEAR-----MYF
. || . ||..||.. ... .|.|||..|||.|.. | ... | | .|. ||
---------------Y--NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYF
QQLISAIDYCHRNG-VAHKDLKAENLLLSDDG---RLLVCDFGFSSKIAKENIDDPEQTIGTGGNAALLDTINNGGMFGTLHYTSPEAVMASSQQWKLAF
|......|.|... . | |.| ||.|....| .. ..|||.|.|. . | .| ..
AQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQ-----------------------------------------
VGNMAVPAETLGIPEDQQQGGPARYSPSSTATPWSSFSTSSSSASHTSSCSGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGT
----------------------------------------------------------------------------------------------------
AHKLSADKRRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLASATNSHKHKWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHA
----------------------------------------------------------------------------------------------------
KPPQEKQTAIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSAAHQPLRHLRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPT
----------------------------------------------------------------------------------------------------
AAGAAKLSTHSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDADVGEFGPPVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHK
.
---------------------------------------------------------------------------------------------------Q
HHHHRHRQPRSNSSSQILGT
. ..... .... ||
---QKMQIWKQQMMWTFCGT
|
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| Kinase | LmjF35.0490.AA | Ciliate-E2 | 25-253 | 17 | 1.5e-35 | 119.48 | In-house | 1-257 (365) | Show / Hide |
Range on Protein: 25-253
Range on HMM: 1-257/365
Sequence Identity: 17% (56 aa)
YVVGHRLGEGAYGSVYVV-KYLPSGDR----------------------FALKILQKQDLFTS-SGIYPV-----AYYDADGGAAPWEAEGAESHPLGGA
| . .|.|..|||| . ... . .|.||..|.... . |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCF------------------------
PVPTVAALAKTFEQQIISEAMVMQALEHPHVVKFYKFLN--STTAFYFVMELAEGGKLLDLILSK-----------SYFAEDEARMYFQQLIS-------
. .| | ... | ||...|.| . ... .|.|||...|| |.|.| .. || | |.. ...|...
-----------Y-KKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAE
--------AIDYCHRNG-VAHKDLKAENLLLSDDGRLLVCDFGFSSKIAKENID--------------DPEQTIGTGGNAALLDTINNGGMF--------
|. |.| .. . | |.| ||.|. . ..|||.| |. ..|.. | . |.| . .
FYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD-------------QIIQQNMFN
---GTLHYTSPE
||..| .||
TICGTPGYMAPE
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| Kinase | LmjF35.0490.AA | RSK | 29-211 | 20 | 1.6e-31 | 111.03 | In-house | 1-154 (278) | Show / Hide |
Range on Protein: 29-211 Range on HMM: 1-154/278 Sequence Identity: 20% (41 aa) HRLG-EGAYGSVYVVKYL---PSGDRFALKILQKQDLFTS--SGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISEAMVMQALE ... .|.||.|.... .| .| |.|.| . .. . | .... . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD------------------------------------------TRHTMTERNILERCQ -HPHVVKFYKFLNSTTAFYFVMELAEGGKLLDLILSKSY---FAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSD---DGRLLVCDFGFS || .|. . . .| .||. .|| |.. .. . . | ||||..|. ....|... | |. | ||| || |. | .|.. ..||||. QHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFC |
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| Kinase | LmjF35.0490.AA | TSSK | 117-211 | 37 | 8.6e-30 | 94.94 | In-house | 68-170 (289) | Show / Hide |
Range on Protein: 117-211 Range on HMM: 68-170/289 Sequence Identity: 37% (39 aa) VMQA-LEHPHVVKFYKFLNSTT-AFYFVMELAEGGKLLDLILSK------SYFAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDGRLLVCDF .| | ||....|| .. .. |.|||.||.| ||. | . |..|| | |..||..||| .|.| ||| ||.||...... || IMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDF GFS ||. GFA |
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| Kinase | LmjF35.0490.AA | CAMK | 703-779 | 26 | 1.1e-29 | 92.28 | In-house | 316-425 (425) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 316-425/425 Sequence Identity: 26% (29 aa) DLWSAGVILFFMLTGRLPFEGR-------------DEEETLHLIQVNEFAFADEE------------AQRISPA--------ARRLVAQMLAPEPTDRPT | ||.||||..||.|..||.| ...|... |. .. | ... .|| .. |. .|| ..|..|.| DMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMT IEQIIANPWF |||. . ||. IEQCLNHPWM |
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| Kinase | LmjF35.0490.AA | CAMKL | 698-779 | 30 | 1.2e-24 | 75.48 | In-house | 213-297 (297) | Show / Hide |
Range on Protein: 698-779 Range on HMM: 213-297/297 Sequence Identity: 30% (27 aa) DPFQQDLWSAGVILFFMLTGRLPFEGRDE------EETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQIIANPWF | .. | ||.||||..|..|.|||.. . . . .... . . ..| .|.| .|| . |..||||.|| ||. DGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | LmjF35.0490.AA | AGC | 703-779 | 22 | 8.1e-24 | 57.08 | In-house | 285-395 (395) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 285-395/395 Sequence Identity: 22% (25 aa) DLWS--AGVILFFMLTGRLPFEGR----------DEEETLHLIQVNEFAFADEEA------------QRISPAARRLVAQMLAPEPTDRPT--------- | || |.... ||||. || | ...|. ..|. .... ... . .|| |. |. ..| ..|..|.. DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDK -IEQIIANPWF .|.| . ||| GAEEIKNHPWF |
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| Kinase | LmjF35.0490.AA | TSSK | 698-779 | 33 | 5.4e-23 | 72.3 | In-house | 206-289 (289) | Show / Hide |
Range on Protein: 698-779 Range on HMM: 206-289/289 Sequence Identity: 33% (28 aa) DPFQQDLWSAGVILFFMLTGRLPFEG--RDEEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQIIANPWF ||.. | || ||||. |..|..|| .. |. .| ...| . ||.... |...||.|.|. ||.|..|....| DPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | LmjF35.0490.AA | Ciliate-E2 | 703-779 | 29 | 5.9e-22 | 72.14 | In-house | 278-365 (365) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 278-365/365 Sequence Identity: 29% (28 aa) DLWSAGVILFFMLTGRLPFEGRDEEETLHLIQVNEFAFADEE--------------AQRISPAARRLVAQ----MLAPEPTDRPT-IEQIIANPWF |.||.||||..||.|..|| . |. ... | .| . .|. . | . || .| |.| .|||. .||| DIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | LmjF35.0490.AA | MARK | 703-779 | 34 | 1.9e-21 | 67.02 | In-house | 188-262 (262) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 188-262/262 Sequence Identity: 34% (27 aa) DLWSAGVILFFMLTGRLPFEGRD--EEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQIIANPWF | || ||.|.||..|..||.| . ..| |. .. . . .|. .| |. ..| . | .|||||.| ||. DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | LmjF35.0490.AA | Ciliate-E2-Unclassified | 703-779 | 28 | 3.1e-20 | 66.9 | In-house | 252-352 (352) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 252-352/352 Sequence Identity: 28% (29 aa) DLWSAGVILFFMLTGRLPFEGRDEEE----------------TLHLIQVNEFAFADEEA----QRISPAARRLVA----QMLAPEPTDRPTIEQIIANPW | || ||||..||.|..||.....|. . |. ... | .. ...|| | .. .|| | |.|.|||. || DIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPW F | F |
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| Kinase | LmjF35.0490.AA | RSK | 703-779 | 34 | 3.4e-20 | 70.75 | In-house | 194-278 (278) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 194-278/278 Sequence Identity: 34% (29 aa) DLWSAGVILFFMLTGRLPFEG---RDEEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPT-----IEQIIANPWF |.|| ||... ||||..|| | . .|.. || ..| . .. | .|..|. |. .|| .| .|.. .|.| ..||| DWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | LmjF35.0490.AA | CAMK1 | 703-779 | 32 | 3.3e-18 | 49.49 | In-house | 198-276 (276) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 198-276/276 Sequence Identity: 32% (26 aa) DLWSAGVILFFMLTGRLPFEGRD-EEETLHLIQVNEFAFADEEAQRISPA-ARRLVAQMLAPEPTDRPTIEQIIANPWF |.||.|||....|.| || . . ..| . .| |. | . || | .. .|| ..|. |.|.||... ||. DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | LmjF35.0490.AA | Pkinase | 703-779 | 28 | 4.3e-18 | 65.06 | Pfam | 194-293 (293) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 194-293/293 Sequence Identity: 28% (29 aa) DLWSAGVILFFMLTGRLPFEGR------DEEETLHLIQVNEFAFADEEAQRIS-----------------PAARRLVAQMLAPEPTDRPTIEQIIANPWF | ||.|.||. ||.||.|| |. |. . . .| .. | .. .|| .... .. .|.. |..|||.||| ||| DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | LmjF35.0490.AA | AMPK | 703-779 | 37 | 1.1e-17 | 49.14 | In-house | 182-254 (254) | Show / Hide |
Range on Protein: 703-779 Range on HMM: 182-254/254 Sequence Identity: 37% (29 aa) DLWSAGVILFFMLTGRLPFEGRDEEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQIIANPWF |.|| ||||. || |.|||. . . | |. . .|| |. |. .|| . |. | ||..| . ||| DIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKF----LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | LmjF35.0490.AA | TyrKc | 25-783 | 6 | 3e-09 | -73.07 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 25-783
Range on HMM: 1-280/280
Sequence Identity: 6% (55 aa)
YVVGHRLGEGAYGSVYVVKYLPSGDRFALKILQKQDLFTSSGIYPVAYYDADGGAAPWEAEGAESHPLGGAPVPTVAALAKTFEQQIISEAMVMQAL--E
. |. |||||.| || .. | | |.. .. ...|| .| | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------------------------------------------REDFMREARIMCKLGGH
HPHVVKFYKFLNST-------TAFYFVMELAEGGKLLDLILSKSY-FAEDEARMYFQQLISAIDYCHRNGVAHKDLKAENLLLSDDGRLLVCDFGFSSKI
||..|..| . . |||....| |.| . .. . .. . | . .| |.... | || | | |...... ..||| | .|
HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDI
AKE-NIDDPEQTIGTGGNAALLDTINN----GGMF-GTLHYTSPEAVMAS-------------------------SQQ-----WKLAFVGNMAVPAETLG
. . . |.. || . . ..||. . . . . | . . .
YDDDQQG------------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP
IPED----QQQGGPARYSPSSTATPWSSFSTSSSSASHTSSCSGSLARGWRRKAAEVVSSKHWKARGKISGKGSGASLRTSNSTSLIDEAGTAHKLSADK
.|..
QPPNDYPMS-------------------------------------------------------------------------------------------
RRVRPDSLTPLPSATEAAAPGSSLHRAGSTHSLASATNSHKHKWVSPTSGLNKVGEGLSILVKSLMGSNGSSSGGHHHHHHSHDSHARSSHAKPPQEKQT
----------------------------------------------------------------------------------------------------
AIVVRSSADAKAKLKRTSSTAAFSVGGEAEEGPSAAHQPLRHLRTNAPSQARVPSPSSGMSPAVSPNTSSFASPRFHESVAAAAACIADSPTAAGAAKLS
----------------------------------------------------------------------------------------------------
THSSPAGSPTDSKSVITSPARHRPGTKDGGAVSDADVGEFGPPVTAFDRDAVGAPPLPLPVPPTTASTLKAPNSSSAPPRTLHHCHQAHEHKHHHHRHRQ
----------------------------------------------------------------------------------------------------
PRSNSSSQILGTSTPCKSQLIIVDPFQQDLWSAGVILFFMLTGRLPFEGRDEEETLHLIQVNEFAFADEEAQRISPAARRLVAQMLAPEPTDRPTIEQII
| . ... .. | . .| |||| ..|
-----------------------------------------------------------------F-----VCCPDEMYQIMKQCWHEDPEDRPTFSEI-
ANPWFRRDL
....
-----HECF
|
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| Kinase | LmjF35.0490.AA | MARK | 25-62 | 28 | 2e-06 | 16.98 | In-house | 1-38 (262) | Show / Hide |
Range on Protein: 25-62 Range on HMM: 1-38/262 Sequence Identity: 28% (11 aa) YVVGHRLGEGAYGSVYVVKYLPSGDRFALKILQKQDLF | .. .|.|.|. |... ...| ..|.||..|..|. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLN |
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| Kinase | LmjF35.0490.AA | AMPK | 25-59 | 40 | 4.7e-05 | 11.02 | In-house | 1-35 (254) | Show / Hide |
Range on Protein: 25-59 Range on HMM: 1-35/254 Sequence Identity: 40% (14 aa) YVVGHRLGEGAYGSVYVVKYLPSGDRFALKILQKQ |..| .|||..| | . . | |.||| || YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQ |
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| Kinase | LmjF35.0490.AA | TSSK | 25-41 | 47 | 0.000977 | 8.12 | In-house | 1-17 (289) | Show / Hide |
Range on Protein: 25-41 Range on HMM: 1-17/289 Sequence Identity: 47% (8 aa) YVVGHRLGEGAYGSVYV | ||. .|.|.|. ||. YNVGKKIGHGSYAKVYC |
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| Kinase | LmjF35.0490.AA | Pkinase_Tyr | 109-153 | 32 | 0.001658 | 12.5 | Pfam | 48-96 (270) | Show / Hide |
Range on Protein: 109-153 Range on HMM: 48-96/270 Sequence Identity: 32% (16 aa) QQIISEAMVMQAL-EHPHVVKFYKFLN-STTA--FYFVMELAEGGKLLD . ..|| .| | ||..|..| | |||....| ||| EDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD |
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| Kinase | LmjF35.0490.AA | Pkinase_Tyr | 25-40 | 56 | 0.136772 | 6.01 | Pfam | 1-16 (270) | Show / Hide |
Range on Protein: 25-40 Range on HMM: 1-16/270 Sequence Identity: 56% (9 aa) YVVGHRLGEGAYGSVY . |. |||||.|.|| ITFGKKLGEGAFGEVY |
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| Efhand | LmjF35.0490.AA | efhand | 936-964 | 31 | 0.000825 | 18.36 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 936-964 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) VLETAFRKVDSDGYGCITRDQVRDMLTTL |. .|...| || | |... ..|...| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | LmjF35.0490.AA | efhand | 1035-1063 | 17 | 2.091883 | 5.9 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 1035-1063 Range on HMM: 1-29/29 Sequence Identity: 17% (5 aa) QLRTAFNSLDESHRGVIQLHQVQRVFERC .|. .|. .| . | | . ....... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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