Gene LmjF22.1170 (L.major)

LmjF22.1170

Species: L.major
Alias: LmajK034, LmjF22.1170
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CIPK

Sequence

Name Sequence Type Origin Length Description Download
LmjF22.1170.AA Protein None 938 None Fasta, JSON
LmjF22.1170.kin_dom Protein Kinase Domain None 183 None Fasta, JSON

Protein domain

Protein domains of LmjF22.1170.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF22.1170.AA CAMK 318-420 21 1.8e-24 75.16 In-house 271-425 (425) Show / Hide 
Range on Protein: 318-420
Range on HMM: 271-425/425
Sequence Identity: 21% (34 aa)

AQGERLHELRGTRHTVA-PEVLRG-------------ESYDPYLADAWALGVVLYFMLNRGRYPHDGA----------------STLRHILHGRVR-PSR
..|. ...  || . .| ||||.|             . |... .| |..||.||.||  |..| .|                  ... |. |. . |. 
TEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPP

P----------------------GLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
.                       .   . ||....||  ||.|. .. .| ||..
YFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF22.1170.AA MARK 334-420 37 7.8e-24 74.94 In-house 173-262 (262) Show / Hide 
Range on Protein: 334-420
Range on HMM: 173-262/262
Sequence Identity: 37% (35 aa)

APEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDGAS----TL-RHILHGRVR-PSRPGLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
|||.. .. || . .| |.||||||||.  |..| ||..    .| . ||.|. . |..  ..  . .|..|||.  ||||  .. |. ||..
APEIFLKKPYDGPKVDIWSLGVVLYFMVC-GYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase LmjF22.1170.AA CAMKL 334-420 28 8.1e-22 66.28 In-house 201-297 (297) Show / Hide 
Range on Protein: 334-420
Range on HMM: 201-297/297
Sequence Identity: 28% (29 aa)

APEVLRG--ESYDPYLADAWALGVVLYFMLNRGRYPHDGAST----------LRHILHGRVRPSRP-GLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
|||.. |  ..|| . .| |..||.||.|.  |..| |...           .. |  |  .|  .  ..  . || ...||  ||.|  .. |. ||..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVC-GYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase LmjF22.1170.AA Pkinase 320-420 23 1.1e-19 70.64 Pfam 166-293 (293) Show / Hide 
Range on Protein: 320-420
Range on HMM: 166-293/293
Sequence Identity: 23% (31 aa)

GERLHELRGTRHTVAPEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDGA---------STLRHILHGRVRPSRP--------------------GLP
.. .. . ||.. .||||.|| .|... .| |..|..|| ||. || | .|.           .. |...... ..|                     ..
NS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWS

SVALDLVSRLLQGSPEERLPVDAILTHPFF
. ..|.....|.  |..|.  . || ||.|
EECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF22.1170.AA Ciliate-E2 269-420 19 1.3e-19 63.97 In-house 147-365 (365) Show / Hide 
Range on Protein: 269-420
Range on HMM: 147-365/365
Sequence Identity: 19% (45 aa)

IRDLFEQAVK---------------GVSHLHQYN-VVHTGIAPDHLLVGTNGLLRISNMVSCCFCAQG--------------------------------
|.....| ..               .. .||. | ..|  | |. .|.     . |. .  . .. .                                 
IKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQ

ERLHELRGTRHTVAPEVLRGESYDP--------YLADAWALGVVLYFMLNRGRYPHDGASTLRHILHGRVRPSRP-----------------GLPSVALD
.  . . || . .|||.|.|..||         | .| |.|||.||.||  |..|      .. |. . .. . |                  ..  . |
NMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-GKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKD

LVSR----LLQGSPEERLP-VDAILTHPFF
| ..    .||  ||.|.   . || ||.|
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF22.1170.AA GIN4 273-420 28 4.3e-18 54.0 In-house 140-293 (293) Show / Hide 
Range on Protein: 273-420
Range on HMM: 140-293/293
Sequence Identity: 28% (44 aa)

FEQAVKGVSHLHQYNVVHTGIAPDHLLVGTNGL-LRISNMVSCCFCAQGERLHELRGTRHTVAPEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDGA
| | . |||  | .|..|  . |. ||.      ..|          ... |.   |  |  |||.  |  |. . .| |. ||.|. .|  |. | |  
FRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLT-GHLPFDEE

-----STLRHILHGRVR-PSRPGLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
       |  . .|.   ||   . . | ||....|   || |. .  || ||  
DGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDILKHPLI
Kinase LmjF22.1170.AA TSSK 333-420 31 1.1e-16 51.23 In-house 195-289 (289) Show / Hide 
Range on Protein: 333-420
Range on HMM: 195-289/289
Sequence Identity: 31% (30 aa)

VAPEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDG-----ASTLRHIL-HGRVRPS--RPGLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
.|||.|||  ||| ..| |..||.|| |.. |. | |         |. .  |..  |   .... . . ||....|| .| .|. ...|. |.  
AAPEILRGIPYDPKWYDVWSMGVILYIMVC-GCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase LmjF22.1170.AA AGC 328-420 23 2.2e-16 37.41 In-house 267-395 (395) Show / Hide 
Range on Protein: 328-420
Range on HMM: 267-395/395
Sequence Identity: 23% (32 aa)

G--TRHTVAPEVLRGESYDPYLADAWA--LGVVLYFMLNRGRYPHDGA-------------STLRHIL------HGRVRPSR---------PGLPSVALD
|  | . .|||.|    |. . .| |.  ||...| ||  |. |  |               .   |.      . .|.  .         . . . | |
GPCTPEYMAPEIL----YG-KACDWWSFGLGCLMYEML-TGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKD

LVSRLLQGSPEERLP----------VDAILTHPFF
|...||.  ||.||           .. |  ||.|
LIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase LmjF22.1170.AA Ciliate-E2-Unclassified 321-420 24 2.3e-15 49.74 In-house 217-352 (352) Show / Hide 
Range on Protein: 321-420
Range on HMM: 217-352/352
Sequence Identity: 24% (34 aa)

ERLHELRGTRHTV----APEVLRGESYDP---YLADAWALGVVLYFMLNRGRYPHDGAS-------------------TLRHILHGRVRPSR-------P
....   ||  .     |||||.|. ||    | .| |.|||.||.||  |.|| .. .                    .. |. . .  .         
QMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF-GYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPK

GLPSVALDLVS----RLLQGSPEERLPVDAILTHPFF
...  | |...    ..|.  |..|.  . || ||.|
HWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF22.1170.AA SNRK 267-420 28 9.5e-15 44.46 In-house 99-254 (254) Show / Hide 
Range on Protein: 267-420
Range on HMM: 99-254/254
Sequence Identity: 28% (46 aa)

SLIRDLFEQAVKGVSHLHQYNVVHTGIAPDHLL-VGTNGLLRISNMVSCCFCAQGERLHELRGTRHTVAPEVLRGESYDPYLADAWALGVVLYFMLNRGR
.| |  | | .. ..  ||  |||  . |.  .     |. ..           ||.|.   |     |||.| |.|||    | |.|||.|| ||  |.
DLARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILY-MLVCGQ

YPHDGAS---TLRHILHGRVR-PSRPGLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
 | . |    ||  |.  .   |..  .     ||. ..|.  |. |  .. |  |.. 
APFQEANDSETLTMIMDCKYTVPDH--VSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase LmjF22.1170.AA S_TKc 18-420 12 2.6e-12 3.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-420
Range on HMM: 1-231/231
Sequence Identity: 12% (50 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEAQWMWNRVAESIRVQRTLPKNKYVLEMVECFESNTSVYMLMRLFPSMNITKLFTDAAARA
||..|..  | |  . ..|||. || .. . . .                                                                  
YEILRKIGKGAF-GKVYKCRHKKTGRIVAIKIIK------------------------------------------------------------------

KLLSCLQAMPQAPAHSSAAATSTGSPTTEPEKTAEGTPHRKLSRLRALPAIDPTTPITPQVTSSITPSATSALKSVSSRGLKTNMRTPSASAAESQSSGH
                                                                                             | |   .
----------------------------------------------------------------------------------------EHIRREIQILKK

GTEEAADANEFFLRGRGKQESTPSTAASTMAI--ASVNAFLGTAVPSH----VPLSLIRDLFEQAVKGVSHLHQYNVVHTGIAPDHLLVGTNGLLRISNM
        |   | .     .        .     ..  ..    .       |   .| .. | .... ..|. ...|  . |. .|. .   . |.  
-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDF

VSCCFCAQGERLHELRGTRHTVAPEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDGASTLRHILHGRVRPSRPGLPSVALDLVSRLLQGSPEERLPV
 ....       . . ||.. .|||||   .|..  .| |..|..|| ||  |. | .   ..  ...  .       .. |.|.....||  ||.|. .
GLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA

DAILT-------HPFF
  .|.       ||.|
-EALQDEWDIKCHPWF
Kinase LmjF22.1170.AA SAK 270-420 25 2.7e-10 31.0 In-house 103-254 (254) Show / Hide 
Range on Protein: 270-420
Range on HMM: 103-254/254
Sequence Identity: 25% (40 aa)

RDLFEQAVKGVSHLHQYNVVHTGIAPDHLLVGTNGLLRISNM-VSCCFCAQGERLHELRGTRHTVAPEVLRGESYDPYLADAWALGVVLYFMLNRGRYPH
|....| | |.  ||  ...|  ..   .|.  .  ..|    .        |.   . ||   ..||.    .     .| |.|| .|| .|  || | 
RHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHG-LQSDVWSLGCMLYTLL-IGRPPF

DG---ASTLRH-ILHGRVRPSRPGLPSVALDLVSRLLQGSPEERLPVDAILTHPFF
|     .||   ..   . |.   |   | ||. ..|.  |.||. ....| ||| 
DTDAVKNTLNKVMMAEYIMPAH--LSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase LmjF22.1170.AA TyrKc 18-420 10 1e-05 -130.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-420
Range on HMM: 1-280/280
Sequence Identity: 10% (47 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEAQWMWNRVAESIRVQRTL-PKNKYVLEMVECFESN-------TSVYMLMRLFPSMNITKL
 .||..|  | | .. .... .       . |  | . ..|        . .|. . | .... .. .. .  .          ....| .         
ITLGKKLGEGAF-GEVYKGTWK-------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY---------

FTDAAARAKLLSCLQAMPQAPAHSSAAATSTGSPTTEPEKTAEGTPHRKLSRLRALPAIDPTTPITPQVTSSITPSATSALKSVSSRGLKTNMRTPSASA
    ..   |.. |..                                                                                    
----MPHGDLKDYLRKHRPK--------------------------------------------------------------------------------

AESQSSGHGTEEAADANEFFLRGRGKQESTPSTAASTMAIASVNAFLGTAVPSHVPLSLIRDLFEQAVKGVSHLHQYNVVHTGIAPDHLLVGTNGLLRIS
                                                      ....   .   |. .| ..||. |..|  .|    ||| |.  .||
------------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKIS

NMVSCCFCAQG-------ERLHELR--GTR--HTV---APEVLRGESYDPYLADAWALGVVLYFMLNRGRYPHDG--------ASTLRHILHGRVRPSRP
    . .   .       .  .     |..    .   |||...   . .   | |. ||... .. .|  |. |        .  .... .|. .|  |
DFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP

G--------LPSVALDLVSRLLQGSPEERLPVDAILTHPFF
          |.   .. ..  .  ||.|    .|  | .|
NDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF22.1170.AA SAK 18-100 26 3.3e-05 13.39 In-house 1-80 (254) Show / Hide 
Range on Protein: 18-100
Range on HMM: 1-80/254
Sequence Identity: 26% (22 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEAQWMWNRVAESIRVQRTLPKNKYVLEMVECFESNTSVYMLMRL
|. . .|  | | |  |  . | |.    ... ||... ..  | .|| . ...   | |   .||. . || |  ||. . .
YQVQHLLGKGGFACVYR-AKCIHTHQEVAIKMIDKKLMQKTG-MVQRVRNEVEIHCQL-KHPSILELYNYFEDNNYVYLVLEM
Kinase LmjF22.1170.AA TSSK 270-290 47 0.000232 10.2 In-house 126-146 (289) Show / Hide 
Range on Protein: 270-290
Range on HMM: 126-146/289
Sequence Identity: 47% (10 aa)

RDLFEQAVKGVSHLHQYNVVH
| .| | |..| ..| .||||
RKWFRQMVSAVKYCHSHNVVH
Kinase LmjF22.1170.AA SNRK 18-58 36 0.000548 8.64 In-house 1-40 (254) Show / Hide 
Range on Protein: 18-58
Range on HMM: 1-40/254
Sequence Identity: 36% (15 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEA
|.| . |  | |    .| ||. || .  |.| ||  . |.
YDLEKTLGRGHFAV-VKLARHVFTGEKVAVKVIDKTKMDEV
Kinase LmjF22.1170.AA CAMKL 18-73 25 0.012539 4.04 In-house 1-61 (297) Show / Hide 
Range on Protein: 18-73
Range on HMM: 1-61/297
Sequence Identity: 25% (16 aa)

YELGRVLATGDFDCRTRLCRH-ITTGVRYVVRVYDKRVLAEAQWMWNR------VAESIRVQR
|..|..| .| |    .|..| .|||... . ..||. . . .||...       .   |..|
YRIGKTLGKGSF-GKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRR
Kinase LmjF22.1170.AA CAMK 34-290 8 0.014201 3.31 In-house 11-202 (425) Show / Hide 
Range on Protein: 34-290
Range on HMM: 11-202/425
Sequence Identity: 8% (28 aa)

RLCRHI-TTG-----------VRYVVRVYDKRVLAE------------------------AQWMWNRVAESIRVQRTLPK------NKYVLEMVECFES-
.||.|. |||           ... . ..||. | .                         . .  .|   |.. ..| .       . .. . | .|. 
KLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDP

------------------NTSVYMLM---------RLFPS----------------MNITKLFTDAAARAKLLSCLQAMPQAPAHSSAAATSTGSPTTEP
                  .. .|| |          ||                                                              
HYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQ-------------------------------------------

EKTAEGTPHRKLSRLRALPAIDPTTPITPQVTSSITPSATSALKSVSSRGLKTNMRTPSASAAESQSSGHGTEEAADANEFFLRGRGKQESTPSTAASTM
                                                                                                    
----------------------------------------------------------------------------------------------------

AIASVNAFLGTAVPSH--VPLSLIRDLFEQAVKGVSHLHQYNVVH
         .  | ..  .. .  | .| | . .| ..|. |.||
---------FDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVH
Kinase LmjF22.1170.AA CAMKL 270-290 38 0.024615 3.09 In-house 130-150 (297) Show / Hide 
Range on Protein: 270-290
Range on HMM: 130-150/297
Sequence Identity: 38% (8 aa)

RDLFEQAVKGVSHLHQYNVVH
| .| | | .|...|. ..||
RRYFRQIVSAVNYCHSHGIVH
Kinase LmjF22.1170.AA Pkinase 18-98 25 0.054435 8.12 Pfam 1-79 (293) Show / Hide 
Range on Protein: 18-98
Range on HMM: 1-79/293
Sequence Identity: 25% (21 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEAQWMWNRV-AESIRVQRTLPKNKYVLEMVECFESNTSVYMLM
|..||..  | |  . ..|.|. || ...| . .||   . ... .|  .| |.. . | . ...... ..||.....|| |
YHIGRKIGSGSF-GCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSE-IQIMKRL-NHPNIVRLYDWFEDKDHIYMVM
Kinase LmjF22.1170.AA Ciliate-E2 77-98 25 0.060183 2.45 In-house 90-113 (365) Show / Hide 
Range on Protein: 77-98
Range on HMM: 90-113/365
Sequence Identity: 25% (6 aa)

KNKYVLEMVECFE--SNTSVYMLM
.......|.|||.  .....|. |
NHPNIIKMYECFQEKDDNNIYLVM
Kinase LmjF22.1170.AA MARK 270-290 42 0.166774 0.88 In-house 107-127 (262) Show / Hide 
Range on Protein: 270-290
Range on HMM: 107-127/262
Sequence Identity: 42% (9 aa)

RDLFEQAVKGVSHLHQYNVVH
| .| | | .|. .|. |.||
RRIFRQIVSAVNYCHSKNIVH
Kinase LmjF22.1170.AA MARK 18-61 27 0.208255 0.56 In-house 1-43 (262) Show / Hide 
Range on Protein: 18-61
Range on HMM: 1-43/262
Sequence Identity: 27% (12 aa)

YELGRVLATGDFDCRTRLCRHITTGVRYVVRVYDKRVLAEAQWM
|...... .| . .  .|..|. ||... . .|.|  | . |||
YKMLKTIGHGSY-AKVKLACHKHTGRKVAIKIYEKFKLNDPQWM
Kinase LmjF22.1170.AA Pkinase 269-290 18 1.033245 3.6 Pfam 110-131 (293) Show / Hide 
Range on Protein: 269-290
Range on HMM: 110-131/293
Sequence Identity: 18% (4 aa)

IRDLFEQAVKGVSHLHQYNVVH
... . | ..|. ..|. ...|
CKFYMYQILRGLEYCHSMGIIH