Gene LmjF34.3020 (L.major)

LmjF34.3020

Species: L.major
Alias: LmjF34.3020, LmajK044
External Links:
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
LmjF34.3020.AA Protein None 940 None Fasta, JSON
LmjF34.3020.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of LmjF34.3020.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF34.3020.AA TTBK 358-587 50 3.6e-107 362.35 In-house 27-257 (257) Show / Hide 
Range on Protein: 358-587
Range on HMM: 27-257/257
Sequence Identity: 50% (118 aa)

EVCIKVE--QENKNVLRLEALALKKVQPCPQVVRYLGSGCTNGMNYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPS
.| ||||  |  | ||..|   ||| | |. | |. | |  .  ||.||. .| |||.|||    |.|.. |||. ||  | .|. .|..|  |||||||
QVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPS

NFVTGLPGTPDHTTCYLIDFGLARRFRRSNGEIRPPRENAGFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWRKYKEKDDIGRCKEESIS
||  |.        ||..||||||..  . ||.||||| |||||| ||||. .|  ||.|| |||||| .|||||. | ||||| | ||..|. ||.   
NFAMGRNPS-TCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDH

PHLVRNLPREFQPFLAHLQTLRYEDEPDYDLL
. |. ..| ||. |..|.. | ||| ||| |.
RMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase LmjF34.3020.AA CK1 307-587 26 2.6e-88 299.69 In-house 1-339 (339) Show / Hide 
Range on Protein: 307-587
Range on HMM: 1-339/339
Sequence Identity: 26% (97 aa)

WIIINRIGAGSFG-ETFAA-----MEVDGPAEEADSLTVAAENLKLLENLPPAEERNEVCIKVEQENKN---VLRLEALALKKV----------------
| ..  || |.|| . . .     . .... ..                     .  |. .||| .. .    ...|.  ..|                 
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPY---------------------KGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKH

-----QPCPQVVRYLGSGCTNG-MNYLVMEKLGSNLAELRR--RSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPG----------
     ..|| ...|  .|....  ||.||. || || .||.  |   . |.  |.|. .. .| |.. .|| | .||||||.||. |. .          
FCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHE

-TPDHTTCYLIDFGLAR-RFRRSNG------------EIRPPRE---NAGFRG-TSRYASVASHHHRELGRVDDLWSLLFMLVEFATGT--LPWRKYKEK
  ..| . |.||||.|| ..|...|            ..|||||   ..|||| | ||.|...| ..|.||.|||||...||.|.  ||  |||.. |..
WNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDE

DD-----IGRCKEESISPHLVRN------------LPREFQPFLAHLQTLRYEDEPDYDLL
.      ... |.|.|.  .  .            .|.|| ... .. .|.|.|.|||. .
MKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase LmjF34.3020.AA TTBKL 357-591 32 1.2e-81 275.37 In-house 25-288 (288) Show / Hide 
Range on Protein: 357-591
Range on HMM: 25-288/288
Sequence Identity: 32% (86 aa)

NEVCIKVEQENK-----NVLRLEALALKKVQ--PCPQVVRYLGSGCTNGMNYLVMEKLGSNLAELRRRSQHGT-FNIYTTLKAGVSCLTAIRGVHDLGLV
... ...|. |.     ... .|.  |.| |  ..| . . ..|| . . |..||. .| ||  ||......  |.  |..  |. || |.. .|| | .
KDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFI

HRDIKPSNFVTGLPG--TPDHTTCYLIDFGLARRFRRSNGEI-----------RPPRE---NAGFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFAT
|||.||.|...|. .  ...  . ||||||.||......||            |.||.    |.|||| ||.|.. | ..|.||.|||||...|..|.. 
HRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHC

GTLPWRKYKEKDDIGRCKEESISPHLVRN------LPREFQPFLAHLQTLRYEDEPDYDLLLTLM
| |||.  ..|..|.  |....   |  .      .|.|| .|  || .||| |.|||. .. ..
G-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase LmjF34.3020.AA Worm6 361-587 32 2.7e-61 209.97 In-house 31-279 (279) Show / Hide 
Range on Protein: 361-587
Range on HMM: 31-279/279
Sequence Identity: 32% (81 aa)

IKVEQ----ENKNVLRLEALALKKV--QPCPQVVRYLGSGCTNG--MNYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDI
.|.|.    . ...|..|.  ||.|  ..|.....    | ..    ||.||. .| ||..||. .  . |   |.|| .  || ||. .|  | .|||.
MKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDV

KPSNFVTGL---PGTPDHTTCYLIDFGLAR--RFRRSNGEIRPPR-ENAGFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWRKYKEKDDI
||.||  |        .| | |..|||..|  ...  ..|.|.|| ...||||| |||..|.| ..|..| ||. | . |.||. .|.||||. |..|. 
KPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHV

GRCKEES---IS----PHLVRNLPR-EFQPFLAHLQTLRYEDEPDYDLL
.. |..    ..      . .. |. ||.  .  . ...|.|.|||. .
EKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase LmjF34.3020.AA CK1 307-585 29 4.4e-41 139.21 In-house 1-271 (271) Show / Hide 
Range on Protein: 307-585
Range on HMM: 1-271/271
Sequence Identity: 29% (88 aa)

WIIINRIGAGSFGETFAAMEVDGPAEEADSLTVAAENLKLLENLPPAEERNEVCIKVEQENKN--VLRLEALALKKVQP------CPQVVRYLGSGCT--
  .. .||.||||. . .. .    ||                       |.| ||.| ...    |  ||  .|  |       |. . .   .|.   
YRVGRKIGQGSFGDIYLGINM-TNGEE-----------------------NHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQ

NGMNYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFR-RSNGEIRPPRENA
. .|..||. || .| .|    . . | ..|.|  .   .. |  ||  ...|||||| ||. |. .  .....|.|||||| |.|  ....  | ||| 
GDYNIMVMDLLGPSLEDLFNFCN-RKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENK

GFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWR--KYKEKDD----IGRCKEESISPHLVRN-LPREFQPFLAHLQTLRYEDEPDYD
.. || ||||. .|  .| .| ||. ||  .|. |. |.|||   | ..|..    |.  |      .| .. .| ||. .| .   |..|..|||.
NLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase LmjF34.3020.AA CK1-D 400-587 36 1.4e-31 108.66 In-house 70-261 (261) Show / Hide 
Range on Protein: 400-587
Range on HMM: 70-261/261
Sequence Identity: 36% (71 aa)

NYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFRRSN-GEIRPPRENAGFR
| .||. ||  | .|    .   | . | |  .   .. |  .|    .|||||| ||. || |   . . |.||||||.|.| ..  .  | |||    
NVMVMDLLGPSLEDLFNYCHR-KFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGL-GKRGN-MVYIIDFGLAKRYRDARTHQHIPYRENKNLT

GTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWRKYK---EKDDIGRCKEESISPH---LVRNLPREFQPFLAHLQTLRYEDEPDYDLL
|| ||||.  |.  |  | ||| || ..|. |. |.|||   |    ..   |  |  .| .   | . .| ||| .... ..|...| |||  |
GTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase LmjF34.3020.AA Dual 400-591 29 1.4e-30 99.98 In-house 87-282 (282) Show / Hide 
Range on Protein: 400-591
Range on HMM: 87-282/282
Sequence Identity: 29% (59 aa)

NYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFRR-SNGEIRPPRENAGFR
.|.||   |. | | ||    | ..  .    .   |.||.  | .| .||.|||.||  ||    | || |. ||...| .   .|.. |..| .  . 
KYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGL--GMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMY

GTSRYASVASHHHRELGRVDDLWS---LLFMLVEFATGTLPWRKYKEKDDIGRCKEE---SISPHLVRNLPREFQPFLAHLQTLRYEDEPDYDLLLTLM
|. |||. |    .. || ||| .   ..| |   . | ..|||  .   .   |..      .| . . ||.. | .     . |.  |||| ..  .
GCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHG-MSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase LmjF34.3020.AA CK1-A 357-587 32 1.2e-29 101.81 In-house 25-261 (261) Show / Hide 
Range on Protein: 357-587
Range on HMM: 25-261/261
Sequence Identity: 32% (77 aa)

NEVCIKVEQENKNV--LRLEALALKKVQPCPQVVRYLGSGCTNGMNYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKP
.|| ||.|...     |  ||   . .| |. . . .  ||    | .||. ||  | .|    .   | . | |      .. |  ||  . .||||||
EEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKR-RFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKP

SNFVTGLPGTPDHTTCYLIDFGLARRFRRSNGEIR-PPRENAGFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWR------KYKEKDDIG
 ||. |.         .|||||||...| |. ..  | ||     || ||||.  |   |  | ||. |. .... |  |.|||       | .  . | 
DNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKIS

RCKEESISPHLVRNLPREFQPFLAHLQTLRYEDEPDYDLL
  |      .| .  | ||  .... . ||.|..|||  |
EKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase LmjF34.3020.AA CK1-Unclassified 442-537 44 8.7e-29 82.1 In-house 120-216 (244) Show / Hide 
Range on Protein: 442-537
Range on HMM: 120-216/244
Sequence Identity: 44% (44 aa)

VHDLGLVHRDIKPSNFVTG-LPGTPDHTTCYLIDFGLARRFRRS--NGEIRPPRENAGFRGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPW
.|  ...|||||| ||. | | .   |...|.|||||. |....  .|.  | ||| .. || ||||. .|   | .| ||| ||   |. |. |.|||
LHNKNFIHRDIKPDNFLMGKLGKN--HHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPW
Kinase LmjF34.3020.AA CK1-G 400-587 32 1.2e-28 94.15 In-house 71-266 (266) Show / Hide 
Range on Protein: 400-587
Range on HMM: 71-266/266
Sequence Identity: 32% (64 aa)

NYLVMEKLGSNLAELRRRSQHGTFNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFR--RSNGEIRPPRENAGF
| .||. ||  |  |       .| . |..   .  .. .. ||.  |. ||.|| ||  | |...|. . ..||||.|. ..  . .  | | ||    
NIMVMDLLGPSLEDLFDWCDR-KFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHI-PYREHKSL

RGTSRYASVASHHHRELGRVDDLWSLLFMLVEFATGTLPWR-----KYKEK-DDIGRCKEESISPHLVRN--LPREFQPFLAHLQTLRYEDEPDYDLL
 || || |.  |  ||  | ||. .|  |   |  | |||        ||. . ||  | .     |. |  .| .|  .|     | ....|||| |
TGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase LmjF34.3020.AA S_TKc 307-595 18 3.9e-15 45.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 307-595
Range on HMM: 1-231/231
Sequence Identity: 18% (56 aa)

WIIINRIGAGSFGETFAAMEVDGPAEEADSLTVAAENLKLLENLPPAEERNEVCIKVEQENKNVLRLEALALKKVQPCPQVVRYLGSGCTNGMNYLVMEK
. |.. || |.||. . . ...                             .| ||.     . .| |   |||   .| .|.....  . .  |.||| 
YEILRKIGKGAFGKVYKCRHKK--------------------------TGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEY

LGS---NLAELRRRSQHGT----FNIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFRRSNGEIRPPRENAGFRG
..    .| .. .. ...     |.  .. .     . |.   |..| .|||.||.|            .  ..||||||..               | |
CDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-------------TTFCG

TSRYAS--VASHHHRELGR-VDDLWSLLFMLVEFATGTLPWRKYKEKDDIGRCKEESISPHLVRNLPREFQPFLAHLQTLRYEDEPDYDLLLT-----LM
|  | .  |        |.   | ||.  .| |...|  |..   . . . .              ..|.  |. .. .   |. |    .|.      .
TPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HRAL
|  .
HPWF
Kinase LmjF34.3020.AA Pkinase 307-538 20 1.6e-13 48.94 Pfam 1-213 (293) Show / Hide 
Range on Protein: 307-538
Range on HMM: 1-213/293
Sequence Identity: 20% (52 aa)

WIIINRIGAGSFGETFAAMEVDGPAEEADSLTVAAENLKLLENLPPAEERNEVCIKVEQENKNVLRL--------EALALKKVQPCPQVVRYLGSGCTNG
. |. .||.||||. . ..... .                           .|..|.    ..            |.  .|... .| .||....  ...
YHIGRKIGSGSFGCVYKCHHKGTGK--------------------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKD

MNYLVMEKL--G-SNLAELR----RRSQHGTF--NIYTTLKAGVSCLTAIRGVHDLGLVHRDIKPSNFVTGLPGTPDHTTCYLIDFGLARRFRRSNGEIR
  |.||| .  | . ...|     . ..||.|     .  .     | ..   |. | .|||.||.|.     |..|  .  ..|||||. |.     . 
HIYMVMEYCEGGLY-VMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-----Y-

PPRENAGFRGTSRYASVASHH-HRELGRVDDLWSLLFMLVEFATGTLPWR
. . . .| ||..|..   .  ... |.  | ||.  .| |...| .|..
NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase LmjF34.3020.AA TTBK 307-327 38 0.000126 12.31 In-house 1-21 (257) Show / Hide 
Range on Protein: 307-327
Range on HMM: 1-21/257
Sequence Identity: 38% (8 aa)

WIIINRIGAGSFGETFAAMEV
| .. .|| | ||| . |...
WKVVKKIGGGGFGEIYEAKDM
Kinase LmjF34.3020.AA CK1-Unclassified 309-325 47 0.001543 6.33 In-house 3-19 (244) Show / Hide 
Range on Protein: 309-325
Range on HMM: 3-19/244
Sequence Identity: 47% (8 aa)

IINRIGAGSFGETFAAM
.| .||.||||| . ..
VIEKIGQGSFGEIYKCI
Kinase LmjF34.3020.AA CK1-A 307-327 28 0.010234 5.22 In-house 1-21 (261) Show / Hide 
Range on Protein: 307-327
Range on HMM: 1-21/261
Sequence Identity: 28% (6 aa)

WIIINRIGAGSFGETFAAMEV
. .. .||.||||. . ....
YRLVRKIGSGSFGDIYLGINI
Kinase LmjF34.3020.AA CK1-Unclassified 398-414 41 0.023152 2.8 In-house 77-93 (244) Show / Hide 
Range on Protein: 398-414
Range on HMM: 77-93/244
Sequence Identity: 41% (7 aa)

GMNYLVMEKLGSNLAEL
..|..||. ||..| .|
DYNIMVMDLLGPSLEDL
Kinase LmjF34.3020.AA TTBKL 307-334 28 0.130184 1.3 In-house 1-28 (288) Show / Hide 
Range on Protein: 307-334
Range on HMM: 1-28/288
Sequence Identity: 28% (8 aa)

WIIINRIGAGSFGETFAAMEVDGPAEEA
| |.  || | ||. . .. . .. ..|
WMIVKMIGEGGFGQVYHVWDMKDKKDCA
Kinase LmjF34.3020.AA CK1-D 307-334 32 0.244492 0.28 In-house 1-28 (261) Show / Hide 
Range on Protein: 307-334
Range on HMM: 1-28/261
Sequence Identity: 32% (9 aa)

WIIINRIGAGSFGETFAAMEVDGPAEEA
. |  .||.||||. .   ..    | |
YRIGRKIGSGSFGDIYHGTNIQTNEEVA