Gene LmjF12.0130 (L.major)

LmjF12.0130

Species: L.major
Alias: LmjF12.0130, LmajK050
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF12.0130.AA Protein None 583 None Fasta, JSON
LmjF12.0130.kin_dom Protein Kinase Domain None 568 None Fasta, JSON

Protein domain

Protein domains of LmjF12.0130.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF12.0130.AA CMGC 9-390 13 5.5e-33 105.03 In-house 1-331 (513) Show / Hide 
Range on Protein: 9-390
Range on HMM: 1-331/513
Sequence Identity: 13% (71 aa)

FTVIEQIGSGNYGSLYRVID---------GEAATLAD--RIIATKKLQDTINHPHV--------------LREVSAQRHAQ---------------KCSP
...|..||.| ||  |. .|         |  |.. .  .|.| ||.     ...               |||..  .| .               |  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQ-AHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHN

HIVKLLHVVPRDR----------------VRAALVLEYVPLDLRTFLNAFYCN---------------QAKSSAPTWCATAGADELKSAAAPPCH-----
.||||. .. ..                 .   || ||.. ||  ..     .               .     |                   |     
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKH-----P-------------------HRRPPH

----IPLIYVRRMLRGLIEALH--CLHARG--IAHRDVKPENILVEP------------LGLGHPLRCVCPPMGSFGPAGEAAGCWVHAPHCPDPRQEER
    ... ..| . . ....|.   .| ..  | ||| ||||||. .                                                     
NIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE----------------------------------------

GVTRPMQPQGTLEPCQFFRRYSVALHHELTGDELASAIHRLHCETCRPCPCARAGAGKHAPQQHRDSSEMKTGNSCAQERQADAVDEESPANVDDGEADK
                                                                                                    
----------------------------------------------------------------------------------------------------

LTAPMSPPLMPD--------VKLCDFGSARHIGTLRLRSAEEQR-------------EELTPGPTTPVYCAPEMMLLQR----------YGTSVDMWAVG
           .        .|.||||.||....     ...|.             . .|.   |  | ||| .|  .          |.|..|||.||
---------D-WNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVG

AILFEMLTG
 |..||.||
CIFAEMYTG
S_TKc LmjF12.0130.AA S_TKc 9-576 13 2e-31 111.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-576
Range on HMM: 1-231/231
Sequence Identity: 13% (77 aa)

FTVIEQIGSGNYGSLYRVIDGEAATLADRIIATKKLQDTINHPHVLREVSAQRHAQKCSPHIVKLLHVVPRDRVRAALVLEYVPL---DLRTFLNAFYCN
......||.| .|. |.... .     .|| | |..       |..||..  ..     |.||||. |      .  .|.||..    ||....    ..
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK-----EHIRREIQILKK---HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRH

QAKSSAPTWCATAGADELKSAAAPPCH--IPLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILVEPLGLGHPLRCVCPPMGSFGPAGEAAGCWVHAPH
                        . .  .|   .|.... ...||  .| .|| |||.||||||.            .   . || | .          
------------------------GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL---------

CPDPRQEERGVTRPMQPQGTLEPCQFFRRYSVALHHELTGDELASAIHRLHCETCRPCPCARAGAGKHAPQQHRDSSEMKTGNSCAQERQADAVDEESPA
                                                                                                    
----------------------------------------------------------------------------------------------------

NVDDGEADKLTAPMSPPLMPDVKLCDFGSARHIGTLRLRSAEEQREELTPGPTTPVYCAPEMMLLQRYGT-SVDMWAVGAILFEMLTGEFFLGVGTLRSF
                                                |    || |.|||..    ||. ..|.|..| ||.|||.|.           
------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------

SGDVVVRDDYCVMHRLNRMFRHLGTPSVEEWRCIAHPHYYPDEMLAHLPQVRDAALFRCLAQPIDTDGSFRRDSGDIKSNGDAKTADVQTDLNVRPSAGT
               ...||...|                                                                            
--------------QMQMMFKKIG----------------------------------------------------------------------------

CSCAQAPVNGTTDSHAARASAPPRDATAARHPLNVSDFLYQHIGESGVDFLRSLLRYDPAKRMTSAEALR-------HPFL
                                            ... ||.| .|..||.||.|  |||.       ||..
-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF12.0130.AA CDK 324-576 18 1.2e-23 72.37 In-house 151-284 (284) Show / Hide 
Range on Protein: 324-576
Range on HMM: 151-284/284
Sequence Identity: 18% (49 aa)

DVKLCDFGSARHIGT-LRLRSAEEQREELTPGPTTPVYCAPEMML-LQRYG--TSVDMWAVGAILFEMLT---GE-FFLGVGTLRSFSGDVVVRDDYCVM
..|. ||| ||  |  .    . | . ..|.   |  | |||  |  ..|.  |..|||.|| |. ||.|   .. .| |                    
RLKIADFGLARAFGIPHQ--MS-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSE----------------I

HRLNRMFRHLGTPSVEEWR-CIAHPHYYPDEMLAHLPQVRDAALFRCLAQPIDTDGSFRRDSGDIKSNGDAKTADVQTDLNVRPSAGTCSCAQAPVNGTT
. | . || .|||. . |  .   |.|                                                                         
DQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------------------------------------------------------

DSHAARASAPPRDATAARHPLNVSDFLYQHIGESGVDFLRSLLRYDPAKRMTSAEALRHPFL
                                    |.| ..| |||.||... .|| ||..
------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF12.0130.AA CDC2 9-169 25 6.9e-17 47.93 In-house 1-136 (301) Show / Hide 
Range on Protein: 9-169
Range on HMM: 1-136/301
Sequence Identity: 25% (43 aa)

FTVIEQIGSGNYGSLYRVIDGEAATLADRIIATKKLQDTINHPH------VLREVSAQRHAQKCS--PHIVKLLHVVPRDRVRAALVLEYVPLDLRTFLN
.. || || | ||  |. .| .  .    |.| ||   . .          .|| |     ..    | ||||  |.     .  .| ||.  ||. .. 
YQKIEKIGEGTYGVVYKCKDMQTNQ----IVALKKIRLEQEDEGDGVPSTAIREISC---LKELKDHPNIVKLHDVIHQ--NKLYMVFEYLDMDLKKYMD

-AFYCNQAKSSAPTWCATAGADELKSAAAPPCHIPLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILV
  .  |                          |.|...|.  .  .....| .|.|.| ||| || |||.
MSIPKN-------------------------KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILI
Kinase LmjF12.0130.AA Pkinase 9-169 19 1.2e-15 56.43 Pfam 1-141 (293) Show / Hide 
Range on Protein: 9-169
Range on HMM: 1-141/293
Sequence Identity: 19% (33 aa)

FTVIEQIGSGNYGSLYRVIDGEAAT-LADRIIATKKLQDTINHPHVL-REVSAQRHAQKCSPHIVKLLHVVPRDRVRAALVLEYVPL-----DLRTFLNA
......||||..|. |. ..       |  ||  ..  .  .  |.. .|..  .. .  .|.||.|.... ...    .|.||..      || ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIST

FYCNQAKSSAPTWCATAGADELKSAAAPPCHI--PLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILV
                             . .  .   ...... ....|  .|..|| |||.||||||.
--------------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI
Kinase LmjF12.0130.AA CDK 9-169 22 5.6e-15 44.21 In-house 1-141 (284) Show / Hide 
Range on Protein: 9-169
Range on HMM: 1-141/284
Sequence Identity: 22% (40 aa)

FTVIEQIGSGNYGSLYRVIDGEAA-TLADRIIATKKLQDTIN----H----PH-VLREVSAQRHAQKCSPHIVKLLHVVPRDR----------VRAALVL
.  .|.|| | ||  |. .| .      ..|.| ||.    .    .    |.  .||.|  ..     |.||||. |.. .            .  .| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL---HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVF

EYVPLDLRTFLNAFYCNQAKSSAPTWCATAGADELKSAAAPPCHIPLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILV
||.. || ...                                      .. ... |...|| .| ..| ||| || |||.
EYMDHDLKKYMD-------------------------------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILI
Kinase LmjF12.0130.AA CDK4 520-576 35 3.3e-14 44.92 In-house 235-290 (290) Show / Hide 
Range on Protein: 520-576
Range on HMM: 235-290/290
Sequence Identity: 35% (20 aa)

RASAPPRDATAARHPLNVSDFLYQHIGESGVDFLRSLLRYDPAKRMTSAEALRHPFL
| .. |.|. . ||| .. ||  .|. ..| |.|   |.|...|||.  ..| ||..
RDVSLPWDHFPQRHPRPFKDFC-PHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase LmjF12.0130.AA Ciliate-E2 321-392 22 1e-13 43.42 In-house 193-294 (365) Show / Hide 
Range on Protein: 321-392
Range on HMM: 193-294/365
Sequence Identity: 22% (24 aa)

LMPDVKLCDFGSARHIGTL----------RLRSAEEQREELTPGPT--------------TPVYCAPEMMLLQR---------YGTSVDMWAVGAILFEM
|.  .|..||| .. . .            .     .... |||                || | |||.   .          |....|.|..| ||.||
LF--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LTGEF
|.|..
LFGKP
Kinase LmjF12.0130.AA Pkinase 324-392 40 2.3e-13 48.34 Pfam 150-210 (293) Show / Hide 
Range on Protein: 324-392
Range on HMM: 150-210/293
Sequence Identity: 40% (28 aa)

DVKLCDFGSARHIGTLRLRSAEEQREELTPGPTTPVYCAPEMML-LQRYGTSVDMWAVGAILFEMLTGEF
.||.||||.|...        .   . .|    || |.|||  .  | ||..||||..| ||.|||.|..
CVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRP
Kinase LmjF12.0130.AA Ciliate-E2-Unclassified 325-392 27 3.1e-13 42.28 In-house 186-268 (352) Show / Hide 
Range on Protein: 325-392
Range on HMM: 186-268/352
Sequence Identity: 27% (23 aa)

VKLCDFGSARHIGTLRLRSAEEQ-------REELTPGPT-TPVYC----APEMMLLQRYGTS----VDMWAVGAILFEMLTGEF
.|..|||....... .    ..|       .....   . || |     |||..  | |..|    .|.|..| ||.|||.|..
IKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase LmjF12.0130.AA CMGC 547-576 43 3.2e-13 38.86 In-house 484-513 (513) Show / Hide 
Range on Protein: 547-576
Range on HMM: 484-513/513
Sequence Identity: 43% (13 aa)

ESGVDFLRSLLRYDPAKRMTSAEALRHPFL
. ..|.|  .|.|||.||.| ..||.||..
PQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF12.0130.AA CDC2 545-576 43 4.9e-13 35.88 In-house 270-301 (301) Show / Hide 
Range on Protein: 545-576
Range on HMM: 270-301/301
Sequence Identity: 43% (14 aa)

IGESGVDFLRSLLRYDPAKRMTSAEALRHPFL
. . |.| |...|.|||.|| .. |||.||..
LDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase LmjF12.0130.AA Ciliate-E2-Unclassified 9-169 17 3.8e-12 38.47 In-house 1-177 (352) Show / Hide 
Range on Protein: 9-169
Range on HMM: 1-177/352
Sequence Identity: 17% (36 aa)

FTVIEQIGSGNYGSLYRVIDGEAATLA-------DRIIATKKLQDTINHPHVLREVSAQRH----------------AQKCSPHIVKLLHVVPRDRVRAA
...|.|||.|..|. |.... .   ..       . .|  .|.. . .  ... .   ...                 .  .|.|||....  .|.    
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCF-QDKQNIY

LVLEYVP-LDLRTFLN--------------------AFYCNQAKSSAPTWCATAGADELKSAAAPPCHIPLIYVR---RMLRGLIEALHCLHARG-IAHR
.|.||.. .||. ...                     | ..|||.                             .   .... ....|  ||  . | ||
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKY-----------------------------KKAKFYFAQILQGLEYLHHKNNIIHR

DVKPENILV
| ||||||.
DIKPENILF
Kinase LmjF12.0130.AA MAPK 324-390 37 7.2e-12 37.11 In-house 155-231 (328) Show / Hide 
Range on Protein: 324-390
Range on HMM: 155-231/328
Sequence Identity: 37% (29 aa)

DVKLCDFGSARHIGTLRLRSAEEQRE------ELTPGPTTPVYCAPEMMLL---QRYGTSVDMWAVGAILFEMLT-G
|.|.|||| ||.| .      .....       .|.  .|  | ||| ||    ..| ..||||.|| |. |||| .
DLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDR
Kinase LmjF12.0130.AA CAMK 324-392 22 1.1e-11 33.16 In-house 234-332 (425) Show / Hide 
Range on Protein: 324-392
Range on HMM: 234-332/425
Sequence Identity: 22% (23 aa)

DVKLCDFGSARHIGTLR-------LRSAEEQREE----------LTPGPTTPVYCA-PEMML--------------LQRYGTSVDMWAVGAILFEMLTGE
..|..||| |...             ..| . ..          ..    || |.| ||. .               . || ..|||..| ||. ||.|.
NIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY

F
.
P
Kinase LmjF12.0130.AA DYRK 550-576 44 3.8e-11 38.16 In-house 294-320 (320) Show / Hide 
Range on Protein: 550-576
Range on HMM: 294-320/320
Sequence Identity: 44% (12 aa)

VDFLRSLLRYDPAKRMTSAEALRHPFL
.||.. .| .||.||.| ..||.||..
KDFIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF12.0130.AA CAMK 544-576 31 4.7e-11 31.13 In-house 385-425 (425) Show / Hide 
Range on Protein: 544-576
Range on HMM: 385-425/425
Sequence Identity: 31% (13 aa)

HIGES--------GVDFLRSLLRYDPAKRMTSAEALRHPFL
.| ..          |..|..|..|| |||| ...|.||..
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF12.0130.AA CAMK 138-169 50 1.4e-10 29.61 In-house 181-212 (425) Show / Hide 
Range on Protein: 138-169
Range on HMM: 181-212/425
Sequence Identity: 50% (16 aa)

VRRMLRGLIEALHCLHARGIAHRDVKPENILV
.||. | ...|.| .| ..|.||| ||||||.
ARRYFRQICSAVHYCHSHNIVHRDLKPENILL
Kinase LmjF12.0130.AA STE 321-391 23 5.4e-10 31.61 In-house 184-265 (359) Show / Hide 
Range on Protein: 321-391
Range on HMM: 184-265/359
Sequence Identity: 23% (22 aa)

LMPDVKLCDFGSARHIGTL--RLRSAE--------EQREEL-----TPGPTTPVYCAPEMMLLQR------YGTSVDMWAVGAILFEMLTGE
|.  ||||||| .  .     .. . .         . ..      ||      . |||... ..      |.|..|.| .|  . ||.||.
LL--VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LmjF12.0130.AA STE 132-169 35 4.1e-09 28.44 In-house 147-185 (359) Show / Hide 
Range on Protein: 132-169
Range on HMM: 147-185/359
Sequence Identity: 35% (14 aa)

HIPLIYVRRMLRGLIEA-LHCLHARGIAHRDVKPENILV
..|   .....| .... |. ||  .| |||.|| |||.
RFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL
Kinase LmjF12.0130.AA CDK4 360-387 57 1e-08 25.78 In-house 175-202 (290) Show / Hide 
Range on Protein: 360-387
Range on HMM: 175-202/290
Sequence Identity: 57% (16 aa)

YCAPEMMLLQRYGTSVDMWAVGAILFEM
| |||  | . | | ||||.|| | .||
YRAPEVLLQSYYNTPVDMWSVGCIFAEM
Kinase LmjF12.0130.AA Ciliate-E2 542-576 25 1e-08 26.02 In-house 326-365 (365) Show / Hide 
Range on Protein: 542-576
Range on HMM: 326-365/365
Sequence Identity: 25% (10 aa)

YQHIGESGVDFLRS----LLRYDPAKRMT-SAEALRHPFL
.... ... |...     .| .|| ||.|   ..| ||..
WKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF12.0130.AA Ciliate-E2 145-169 57 1.7e-08 25.28 In-house 169-194 (365) Show / Hide 
Range on Protein: 145-169
Range on HMM: 169-194/365
Sequence Identity: 57% (15 aa)

LIEALHCLHARG-IAHRDVKPENILV
.|.||. || .. | ||| ||||||.
IILALEYLHSKNNIIHRDIKPENILF
Kinase LmjF12.0130.AA MAPK 550-576 48 2.1e-08 24.93 In-house 302-328 (328) Show / Hide 
Range on Protein: 550-576
Range on HMM: 302-328/328
Sequence Identity: 48% (13 aa)

VDFLRSLLRYDPAKRMTSAEALRHPFL
.|.|  .|  || || | .|||.||..
IDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF12.0130.AA STE 547-576 37 1.5e-07 22.87 In-house 328-359 (359) Show / Hide 
Range on Protein: 547-576
Range on HMM: 328-359/359
Sequence Identity: 37% (12 aa)

ESGVDFLRSLLRYDPAKRMTSAEALR--HPFL
..  ||..  |..|| || |. . |.  |||.
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF12.0130.AA Pkinase 547-576 40 1.7e-07 27.58 Pfam 264-293 (293) Show / Hide 
Range on Protein: 547-576
Range on HMM: 264-293/293
Sequence Identity: 40% (12 aa)

ESGVDFLRSLLRYDPAKRMTSAEALRHPFL
|.. ||....|..||.|| | ...| ||..
EECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF12.0130.AA CDK4 128-169 40 1.9e-07 21.38 In-house 102-143 (290) Show / Hide 
Range on Protein: 128-169
Range on HMM: 102-143/290
Sequence Identity: 40% (17 aa)

APPCHIPLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILV
.||  .|   ...| . |. ..  ||.  | ||| ||.||||
CPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILV
Kinase LmjF12.0130.AA Ciliate-E2-Unclassified 534-576 23 5.8e-07 20.21 In-house 302-352 (352) Show / Hide 
Range on Protein: 534-576
Range on HMM: 302-352/352
Sequence Identity: 23% (12 aa)

PLNVSDFLY----QHIGESGVDFLR----SLLRYDPAKRMTSAEALRHPFL
..... |      .|. ... ||..    ..| ..| ||.|  ..| ||..
NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF12.0130.AA CDC2 360-389 50 8.4e-07 16.37 In-house 171-204 (301) Show / Hide 
Range on Protein: 360-389
Range on HMM: 171-204/301
Sequence Identity: 50% (17 aa)

YCAPEMML-LQRYGTSVDMWAVGAILFEM---LT
| ||| .|  .|| |.||||..| |. ||    |
YRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVT
Kinase LmjF12.0130.AA DYRK 360-394 42 1e-06 21.28 In-house 170-204 (320) Show / Hide 
Range on Protein: 360-394
Range on HMM: 170-204/320
Sequence Identity: 42% (15 aa)

YCAPEMMLLQRYGTSVDMWAVGAILFEMLTGEFFL
| ||| .|  .|....||| .| || |..||. ..
YRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLF
Kinase LmjF12.0130.AA CAMK 14-92 16 2e-05 12.7 In-house 1-143 (425) Show / Hide 
Range on Protein: 14-92
Range on HMM: 1-143/425
Sequence Identity: 16% (23 aa)

QIGSGNYGSLYRVIDGEA-------------ATLADRIIATKKLQD-------------------------TINHPHVLREVSAQRHAQK-----CSPHI
..|.|..|  ...|. .                 |  || .|||.|                           .   |.||..  .. |.       |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLHVVPRDRV------------------RAALVL---EYVP
.||..|   ...                  .  .|.   ||..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCS
Kinase LmjF12.0130.AA CDK4 9-99 31 3.3e-05 13.57 In-house 1-99 (290) Show / Hide 
Range on Protein: 9-99
Range on HMM: 1-99/290
Sequence Identity: 31% (32 aa)

FTVIEQIGSGNYGSLYRVIDGEAATLADRIIATKKLQDTINHP------HVLREVSAQRH-AQKCSPHIVKLL---HVVPRDR--VRAALVLEYVPLDLR
.  .  ||.| ||  ||. | .      ...| |.    |.         ..||.|  || .|.  | ||||.   ||  .||  .   .|.| .  ||.
YQCVAEIGEGAYGTVYRARDLHTG----HFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLH

TFL
|.|
TYL
Kinase LmjF12.0130.AA MAPK 152-169 55 4.3e-05 13.31 In-house 133-150 (328) Show / Hide 
Range on Protein: 152-169
Range on HMM: 133-150/328
Sequence Identity: 55% (10 aa)

LHARGIAHRDVKPENILV
.|  .. ||| ||.||||
IHSANVIHRDLKPSNILV
Kinase LmjF12.0130.AA DYRK 133-169 36 7e-05 14.5 In-house 100-137 (320) Show / Hide 
Range on Protein: 133-169
Range on HMM: 100-137/320
Sequence Identity: 36% (14 aa)

IPLIYVRRMLRGLIEALHCLHAR-GIAHRDVKPENILV
..| .||.... . ..|  ||    | | | |||||..
FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIML
Kinase LmjF12.0130.AA TyrKc 9-576 10 0.00012 -147.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-576
Range on HMM: 1-280/280
Sequence Identity: 10% (61 aa)

FTVIEQIGSGNYGSLYR-VIDGEAATLADRIIATKKLQDTINHPHVLREVSAQRHA-QKCSPHIVKLLHVVPRDR------VRAALVLEYVPL-DLRTFL
 | ....|.|..|  |. . .        .  | |.|..   .   .|| .  ..   .  |.||.|. |.  .           .|.||.|. ||. .|
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA-REDFMREARIMCKLGGHH-PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

----NAFYCNQAKSSAPTWCATAGADELKSAAAPPCHIPLIYVRRMLRGLIEALHCLHARGIAHRDVKPENILVEPLGLGHPLRCVCPPMGSFGPAGEAA
    .                                ...     .     .    || ... |||    |.||   .                      
RKHRPK-------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------

GCWVHAPHCPDPRQEERGVTRPMQPQGTLEPCQFFRRYSVALHHELTGDELASAIHRLHCETCRPCPCARAGAGKHAPQQHRDSSEMKTGNSCAQERQAD
                                                                                                    
----------------------------------------------------------------------------------------------------

AVDEESPANVDDGEADKLTAPMSPPLMPDVKLCDFGSARHIGTL---RLRSAEEQREELTPGPT--TPV-YCAPEMMLLQRYGTSVDMWAVGAILFEMLT
                             || .||| .| |.        | .  |   . |     |.  .||| .   .. |  | |. |  ..|..|
----------------------------TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFT

GEFFLGVG-TLRSFSGDVVVRDDYCVMHRLNRMFRHLGTPSVEEWRCIAHPHYYPDEMLAHLPQVRDAALFRCLAQPIDTDGSFRRDSGDIKSNGDAKTA
       | ... .  .  |. .    .|. ..  ..  | .                                                          
YGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY--P-MS---------------------------------------------------------

DVQTDLNVRPSAGTCSCAQAPVNGTTDSHAARASAPPRDATAARHPLNVSDFLYQHIGESGVDFLRSLLRYDPAKRMTSAEALRHPFL
                                                   |   .  .   .  ..  ..||..| | .|   | ..
---------------------------------------------------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF12.0130.AA Ciliate-E2 9-55 13 0.00018 11.24 In-house 1-96 (365) Show / Hide 
Range on Protein: 9-55
Range on HMM: 1-96/365
Sequence Identity: 13% (13 aa)

FTVIEQIGSGNYG-----SLYRV----------------------------------IDGEAATLADRII----------ATKKLQDTINHPHVLR
. .|..||.||.|     . ..|                                   . |.    ..|.            |... ..|||....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIK
Kinase LmjF12.0130.AA STE 9-28 35 0.000654 9.84 In-house 1-20 (359) Show / Hide 
Range on Protein: 9-28
Range on HMM: 1-20/359
Sequence Identity: 35% (7 aa)

FTVIEQIGSGNYGSLYRVID
.. ||.||.|..|. |. ..
WEGIEKIGKGAFGTVYKAMN
Kinase LmjF12.0130.AA MAPK 9-57 21 0.000766 8.91 In-house 1-55 (328) Show / Hide 
Range on Protein: 9-57
Range on HMM: 1-55/328
Sequence Identity: 21% (12 aa)

FTVIEQIGSGNYGSLYRVIDGEAATL--ADRIIATKKLQ----DTINHPHVLREV
.. ...||.| ||    .|| .  .    ....| ||..    ...   ...||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREI
Kinase LmjF12.0130.AA DYRK 323-337 33 0.025105 4.84 In-house 144-158 (320) Show / Hide 
Range on Protein: 323-337
Range on HMM: 144-158/320
Sequence Identity: 33% (5 aa)

PDVKLCDFGSARHIG
...|..||||. ...
STIKVIDFGSSCFEH