Gene LmjF27.1940 (L.major)

LmjF27.1940

Species: L.major
Alias: LmajK051, LmjF27.1940
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF27.1940.AA Protein None 960 None Fasta, JSON
LmjF27.1940.kin_dom Protein Kinase Domain None 488 None Fasta, JSON

Protein domain

Protein domains of LmjF27.1940.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF27.1940.AA CDK 496-765 27 8.7e-77 245.17 In-house 91-284 (284) Show / Hide 
Range on Protein: 496-765
Range on HMM: 91-284/284
Sequence Identity: 27% (78 aa)

KDVFLVMDYCPYDLGSYMRRYATAAELHGDGGDCKSTRASAQVPYFHITPRNAHPQAAASYVARAKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDG
. ...|..|...|| .||.                                              |.. .|.||.....|. .|.|||||..| |. ..|
NKLYMVFEYMDHDLKKYMD---------------------------------------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNG

Y-----VKVCDFGLGRLYR-------EGQALTPTVVTLMYRAPELHFGVVDYS--HKMDVWSVGCIFAELFL---RRPLFHASTDSHHLLAVCEVLGIPT
      .|. |||| |..        . ...|. |||| |||||| .|  .||     |.|||||||||.|.   |.|||. ... . |  .....| ||
EVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPT

EESFPGLYHLPQTKTMMQSLPRWNRTSRLASLFQRGAVLPTVAHGDVPVAAEGALLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
|.. ||. .||                                                  ||| . |. .| .| || .|||||.|
EDNWPGVTKLPDY------------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF27.1940.AA CMGC 278-765 15 5.7e-76 248.91 In-house 1-513 (513) Show / Hide 
Range on Protein: 278-765
Range on HMM: 1-513/513
Sequence Identity: 15% (104 aa)

YTRVGRISQGVYGVVFRAVTTADYERQHRQQSRHRVARPGSAASSAAVPSARV---------RTYALKHIK-KMWLEDSQV------GLPPYLMREIDLL
|. ...| .| ||||.... .   ...                                   . .|.| || .   |. .       |.|    ||| .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKD------------------------NGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKIL

LRLQ-----------------HPNIMGALELVL-------------LDPTPVPRRLASPPESCSPSSSSESSSSSSSSESPSTEQHAEEATECDRALRRL
 .|.                 |.|| . .. .              .                                                     
KHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHI-----------------------------------------------------

RSTTEDTAGQNLAKKAKIDNAEEPPPQREEARPATQAQPTGEKGTAQDAAATRPLAAVGAASKAKDVFLVMDYCPYDLGSYMRRYAT-------------
                                                         .    . ....||..|...||  |.... .             
---------------------------------------------------------I-SQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEH

--AAELHGDGGDCKSTRASAQVPYFHITPRNAHPQAAASYVARA-----KSIV------YQILRAVA--FLHDSR--ILHRDLKTSNVLLREDGYV----
  . .                                     |      |...      |||||...  ..|  .  |.||||| .|.|. ... .    
ENKHP------------------------------------HRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRM

----------------KVCDFGLGRLYREG----------------------QALTPTVVTLMYRAPELHFGV---------VDYSHKMDVWSVGCIFAE
                |.||||| | | .                       ...|. |||. |||||. .|           .|. ..|.|||||||||
MWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAE

LFLR--------RPLFHASTD-----------SHHLLAVCEVLGIPT---------------EESFPGLYHLPQTKTMMQSL------------------
....        .|||. ...            ..|   ..||| ||               || .|.   ||  .....                    
MYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQ

----PRWNRTSRLASLFQRGAVLPTVAHGD----------VPVAAEGA--------LLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
      | .   . .|| .   . .                ... .          .... ..|||   ||..| .|..|..|||||.|
SNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSH-KFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF27.1940.AA CDC2 498-765 32 6.8e-60 182.53 In-house 75-301 (301) Show / Hide 
Range on Protein: 498-765
Range on HMM: 75-301/301
Sequence Identity: 32% (89 aa)

VFLVMDYCPYDLGSYMRRYATAAELHGDGGDCKSTRASAQVPYFHITPRNAHPQAAASYVARAKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYV
...| .|. .||  ||...                                        ..  ||. ||||..|.|.|  ||.||||| .| |. ..| .
LYMVFEYLDMDLKKYMDMSIPKN--------------------------------KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNI

KVCDFGLGRLYRE-GQALTPT--VVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAEL---FLRRPLFHASTDSHHLLAVCEVLGIPTEESFPGLYHLPQT
|. ||||.|       ..|.   |||| |||||. .|  .||   |.||.||||||.     ..||||.      |  . ..|| |.|...||.. ||  
KIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDY

KTMMQSLPRWNRTSRLASLFQR---GAVLPTVAHGDVPVAAEGALLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
|   .. |||...  | ... .   .               .   |.. |.||| . || .| .| || ||||||.|
K---NTFPRWKPQD-LSKICPNNQKK-------------KNQ-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase LmjF27.1940.AA Pkinase 560-765 26 3e-52 184.69 Pfam 110-293 (293) Show / Hide 
Range on Protein: 560-765
Range on HMM: 110-293/293
Sequence Identity: 26% (58 aa)

AKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYV----KVCDFGLGRL--YREGQALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELFL
.|...|||||.....|. .|.||||| .|.|. ..|..    |.||||| ..  |  .. .|  ..|. |.|||.. |  .|..| |.||.|||..|...
CKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC

RRPLFHAS----TDSHHLLAVCEVLGIPTEESFPGLYHLPQTKTMMQSLPRWNRTSRLASLFQRGAVLPTVAHGDVPVAAEGALLPESGVDLLASVLQWN
.||.|  .    .   ..  .|...| |.....| ..  .  .  ..   .                         . . .  ...|.. |.. . |...
GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------------------F-HWTFHNWSEECKDFIKWCLCKD

PRRRPSAAEALQHPFF
| .||.|...||||.|
PKKRPTAEQILQHPWF
Kinase LmjF27.1940.AA MAPK 561-765 30 7.1e-52 177.63 In-house 118-328 (328) Show / Hide 
Range on Protein: 561-765
Range on HMM: 118-328/328
Sequence Identity: 30% (69 aa)

KSIVYQILRA--VAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREGQ---------------ALTPTVVTLMYRAPELHFG--VVDYSHKMDV
....|||||.  . ..|  ...||||| ||.|. |.. .|.||||| |     .                .|. |.|  |||||. ..    .|. ..|.
QYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDM

WSVGCIFAELFL-RRPLFHASTDSHHLLAVCEVLGIPTEESFPGLYHLP-QTKTMMQSL--PRWNRTSRLASLFQR--GAVLPTVAHGDVPVAAEGALLP
|||||||||.   |.|||  .   . .  . |||| |.||    .   .   ... |||  ...     ....|    .                  .  
WSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICM-SEHARNYIQSLGNLPKYPKKPWEKMFPNANF------------------NAN

ESGVDLLASVLQWNPRRRPSAAEALQHPFF
   .|||   |...| .| ...||||||.|
PQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF27.1940.AA CDK7 561-689 43 1.5e-48 127.15 In-house 105-234 (288) Show / Hide 
Range on Protein: 561-689
Range on HMM: 105-234/288
Sequence Identity: 43% (57 aa)

KSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYRE-GQALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELFLRRPLFH
|..  ..|. . ..|   |||||||  | |. |.| .|. |||| | |    ...|. |||  |||||| ||   |    |.|||||||||| || | . 
KAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLP

ASTDSHHLLAVCEVLGIPTEESFPGLYHLP
   |   |  ... || ||||  |..  ..
GDSDIDQLTRIFQTLGTPTEEEWPNMCCMM
Kinase LmjF27.1940.AA PITSLRE 561-694 47 3.1e-48 166.56 In-house 109-243 (295) Show / Hide 
Range on Protein: 561-694
Range on HMM: 109-243/295
Sequence Identity: 47% (64 aa)

KSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREG-QALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELFLRRPLFH
|. . | ||.|...||  |.|||||||| |.   |  |.|||||.| | .   ..|| |||| ||||||  |   ||   |.|||||||||. . .||| 
KCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQ

ASTDSHHLLAVCEVLGIPTEESFPGLYHLPQTKTM
 . .   .  .   .| ||| . ||   ||  | |
GKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMM
Kinase LmjF27.1940.AA CDK5 560-710 36 3.9e-41 127.42 In-house 100-252 (287) Show / Hide 
Range on Protein: 560-710
Range on HMM: 100-252/287
Sequence Identity: 36% (57 aa)

AKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREG---QALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELF-LRR
.||. || |. .|| |. ..||||||  | |    |  |  |||| | .  |   .  .  |||| ||.|   .|   ||   |.||.||||||.    |
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAF--GIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGR

PLFHASTDSHHLLAVCEVLGIPTEESFPGLYHLPQTKTMMQSLPRWNRTSRLASL
|||  . ..  |  . ...| |.|.. |.. .||. |  .| .| .. .  ....
PLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQI
Kinase LmjF27.1940.AA CDK4 560-683 50 3.4e-40 135.49 In-house 112-234 (290) Show / Hide 
Range on Protein: 560-683
Range on HMM: 112-234/290
Sequence Identity: 50% (62 aa)

AKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREGQALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELFLRRPLFH
.| .  |.||.| |||  || |||||  |.|.  || ||  |||| | |    |||| |||| |||||       |    | |||||||||.. ||||| 
IKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCIFAEMYCRRPLFC

ASTDSHHLLAVCEVLGIPTEESFP
 . .   |  . .| | |.|.  |
GQSEKDQLHKIFDVMGLPPEDDWP
Kinase LmjF27.1940.AA S_TKc 278-765 14 2.1e-39 138.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 278-765
Range on HMM: 1-231/231
Sequence Identity: 14% (75 aa)

YTRVGRISQGVYGVVFRAVTTADYERQHRQQSRHRVARPGSAASSAAVPSARVRTYALKHIKKMWLEDSQVGLPPYLMREIDLLLRLQHPNIMGALELVL
|. .  | .| .|.|.... .                                | .|.| ||                                      
YEILRKIGKGAFGKVYKCRHKK-----------------------------TGRIVAIKIIK--------------------------------------

LDPTPVPRRLASPPESCSPSSSSESSSSSSSSESPSTEQHAEEATECDRALRRLRSTTEDTAGQNLAKKAKIDNAEEPPPQREEARPATQAQPTGEKGTA
                                                                                           .   |    
------------------------------------------------------------------------------------------EHIRREIQIL

QDAAATRPLAAVGAASKAKDVFLVMDYCPY---DLGSYMRRYAT------AAELHGDGGDCKSTRASAQVPYFHITPRNAHPQAAASYVARAKSIVYQIL
.           ..    .....||.||.    || .|.... .        | |                                    |....|||.
KK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H------------------------------------ARFYMYQIC

RAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREGQALTPTVVTLMYRAPELHFGVVDYSH-KMDVWSVGCIFAELFLRRPLFHASTDSHHL
.|....|. .|.||||| .|.|| |   .|.||||| |..      |  ..|. |.|||.      |.. | |.||.|||..|.. ..|.|.      ..
CALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QM

LAVCEVLGIPTEESFPGLYHLPQTKTMMQSLPRWNRTSRLASLFQRGAVLPTVAHGDVPVAAEGALLPESGVDLLASVLQWNPRRRPSAAEALQ------
 .. ...|                                                           .... |..   ||..|..||.| ||||      
QMMFKKIG-----------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPFF
 ||.|
CHPWF
Kinase LmjF27.1940.AA CDK10 558-689 42 9.2e-39 132.31 In-house 100-232 (285) Show / Hide 
Range on Protein: 558-689
Range on HMM: 100-232/285
Sequence Identity: 42% (56 aa)

ARAKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYRE-GQALTPTVVTLMYRAPELHFGVVDYSHKMDVWSVGCIFAELFLRRP
.. | |. |.||.. .|||  ..||||| ||.|. ..| .|| |||| | |    . .|| .||| |||||| .|  .    .|.| |||| .|| . .|
TQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

LFHASTDSHHLLAVCEVLGIPTEESFPGLYHLP
|.  . . | .  . ..|| | |. .||  .||
LMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLP
Kinase LmjF27.1940.AA CRK7 561-696 29 1.4e-35 120.0 In-house 115-291 (343) Show / Hide 
Range on Protein: 561-696
Range on HMM: 115-291/343
Sequence Identity: 29% (52 aa)

KSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYRE---GQALTPTVVTLMYRAPELHFGVVDY----------------------
|..  |.|  .. .|.  .||||.| ||.|.   | ||  |||| |||      . .|  |.|| ||.|||  |   |                      
KCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLI

----------------SHKMDVWSVGCIFAELFLRRPLFHASTDSHHLLAVCEVLGIPTEESFPGLYHLPQTKTMMQ
                    |.||.|||..||| ..|.| ..     |  . .. | |. .. | .. ||  .||..
SIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKP
Kinase LmjF27.1940.AA CDK5 734-765 56 1.6e-11 32.19 In-house 256-287 (287) Show / Hide 
Range on Protein: 734-765
Range on HMM: 256-287/287
Sequence Identity: 56% (18 aa)

LPESGVDLLASVLQWNPRRRPSAAEALQHPFF
| | | |||   || ||  | ||..||.||.|
LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase LmjF27.1940.AA CDK4 736-765 46 1.5e-10 32.21 In-house 261-290 (290) Show / Hide 
Range on Protein: 736-765
Range on HMM: 261-290/290
Sequence Identity: 46% (14 aa)

ESGVDLLASVLQWNPRRRPSAAEALQHPFF
..| |||   | .|. .|.|| ..||||.|
KQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase LmjF27.1940.AA TyrKc 278-765 10 6.2e-09 -78.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 278-765
Range on HMM: 1-280/280
Sequence Identity: 10% (59 aa)

YTRVGRISQGVYGVVFRAVTTADYERQHRQQSRHRVARPGSAASSAAVPSARVRTYALKHIK---KMWLEDSQVGLPPYLMREIDLLLRL--QHPNIM--
 |    .  | .|.|.... .                                       |.   ||  ||.       .|||. .. .|  .||||   
ITLGKKLGEGAFGEVYKGTWK---------------------------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRL

--------------------------GALELVLLDPTPVPRRLASPPESCSPSSSSESSSSSSSSESPSTEQHAEEATECDRALRRLRSTTEDTAGQNLA
                          |.|   | .. |                                                              
YGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-------------------------------------------------------------

KKAKIDNAEEPPPQREEARPATQAQPTGEKGTAQDAAATRPLAAVGAASKAKDVFLVMDYCPYDLGSYMRRYATAAELHGDGGDCKSTRASAQVPYFHIT
                                                                                                    
----------------------------------------------------------------------------------------------------

PRNAHPQAAASYVARAKSIVYQILRAVAFLHDSRILHRDLKTSNVLLREDGYVKVCDFGLGRLYREG----------QA----LTPTVVTLMYRAPE-LH
            ..   |. .|| .  ..||. .. |||| . |.|. |.. ||..|||| |   ..           .     . |.. .   ||| . 
----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

FGVVDYSHKMDVWSVGCI------FAELFLRRPLF--HASTDSHHLLAVCEVLGIPTE----ESFPGLYHLPQTKTMMQSLPRWNRTSRLASLFQRGAVL
.|.  ...| |||| |        . .     . .     .. ....   . . .| .                                          
YGK--FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------

PTVAHGDVPVAAEGALLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
                 |.   ..  .  . .|  ||. .|   | .|
-----------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF27.1940.AA PITSLRE 731-765 40 6.4e-09 28.81 In-house 261-295 (295) Show / Hide 
Range on Protein: 731-765
Range on HMM: 261-295/295
Sequence Identity: 40% (14 aa)

GALLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
.... . | |||   |  || .| .| .||.||.|
ENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase LmjF27.1940.AA CDK7 739-765 29 6.4e-09 19.43 In-house 262-288 (288) Show / Hide 
Range on Protein: 739-765
Range on HMM: 262-288/288
Sequence Identity: 29% (8 aa)

VDLLASVLQWNPRRRPSAAEALQHPFF
.||..  .  || .| .....|..|.|
LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase LmjF27.1940.AA Pkinase_Tyr 489-604 21 1.9e-08 29.25 Pfam 70-157 (270) Show / Hide 
Range on Protein: 489-604
Range on HMM: 70-157/270
Sequence Identity: 21% (26 aa)

VGAAS-KAKD--VFLVMDYCPY-DLGSYMRRYATAAELHGDGGDCKSTRASAQVPYFHITPRNAHPQAAASYVARAKSIVYQILRAVAFLHDSRILHRDL
.|. . . .   ...|| |.|. || .| |.                                  ..  .  . .  .. .|| .. ..|.. .. ||||
YGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR--------------------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

KTSNVLLREDGYVKVCDFGL
 . |.|. |.. ||.|||||
AARNCLVTENNVVKICDFGL
Kinase LmjF27.1940.AA CRK7 733-765 39 6.3e-08 23.21 In-house 311-343 (343) Show / Hide 
Range on Protein: 733-765
Range on HMM: 311-343/343
Sequence Identity: 39% (13 aa)

LLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
..|.  .|||   |  .|  | .| |.|||..|
FMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase LmjF27.1940.AA Pkinase 278-369 21 5e-06 22.27 Pfam 1-62 (293) Show / Hide 
Range on Protein: 278-369
Range on HMM: 1-62/293
Sequence Identity: 21% (21 aa)

YTRVGRISQGVYGVVFRAVTTADYERQHRQQSRHRVARPGSAASSAAVPSARVRTYALKHIKKMWLEDSQVG-----LPPYLMREIDLLLRLQHPNI
|.....| .| .|.|....   . .                             ..|.| |||   |.|..      |     .|| ...||.||||
YHIGRKIGSGSFGCVYKCHHKGTGK-----------------------------IVAVKIIKKR-HEKSWKDQTHRRL-----SEIQIMKRLNHPNI
Kinase LmjF27.1940.AA CDK10 733-765 36 0.000252 10.66 In-house 253-285 (285) Show / Hide 
Range on Protein: 733-765
Range on HMM: 253-285/285
Sequence Identity: 36% (12 aa)

LLPESGVDLLASVLQWNPRRRPSAAEALQHPFF
.| .||  ||  .. .||..|  | |.|.  .|
WLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase LmjF27.1940.AA CDK10 338-376 38 0.000339 10.2 In-house 29-67 (285) Show / Hide 
Range on Protein: 338-376
Range on HMM: 29-67/285
Sequence Identity: 38% (15 aa)

IKKMWLEDSQVGLPPYLMREIDLLLRLQHPNIMGALELV
.||. ..  . |||   .||| ||....|.||.   | |
LKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVV
Kinase LmjF27.1940.AA CDK5 333-369 40 0.000401 8.39 In-house 27-60 (287) Show / Hide 
Range on Protein: 333-369
Range on HMM: 27-60/287
Sequence Identity: 40% (15 aa)

YALKHIKKMWLEDSQVGLPPYLMREIDLLLRLQHPNI
.||| ..   |..   | |   .||| ||  |.|.||
VALKRVR---LDSEDEGVPSTAIREICLLKELKHKNI
Kinase LmjF27.1940.AA CDK 278-295 44 0.000454 8.73 In-house 1-18 (284) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/284
Sequence Identity: 44% (8 aa)

YTRVGRISQGVYGVVFRA
| .. .| .| ||||..|
YEKLEKIGEGTYGVVYKA
Kinase LmjF27.1940.AA PITSLRE 278-296 47 0.000529 10.71 In-house 1-19 (295) Show / Hide 
Range on Protein: 278-296
Range on HMM: 1-19/295
Sequence Identity: 47% (9 aa)

YTRVGRISQGVYGVVFRAV
.  . ||  |.||||.||.
FQCLNRIHEGTYGVVYRAK
Kinase LmjF27.1940.AA CDC2 278-295 38 0.000907 6.88 In-house 1-18 (301) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/301
Sequence Identity: 38% (7 aa)

YTRVGRISQGVYGVVFRA
|... .|  | ||||...
YQKIEKIGEGTYGVVYKC
Kinase LmjF27.1940.AA CDC2 338-369 42 0.002377 5.57 In-house 29-63 (301) Show / Hide 
Range on Protein: 338-369
Range on HMM: 29-63/301
Sequence Identity: 42% (15 aa)

IKKMWLEDSQVG--LPPYLMREIDLLLRLQ-HPNI
.||  ||  . |   |   .||| .|  |. ||||
LKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNI
Kinase LmjF27.1940.AA CDK7 334-371 33 0.005093 3.4 In-house 28-66 (288) Show / Hide 
Range on Protein: 334-371
Range on HMM: 28-66/288
Sequence Identity: 33% (13 aa)

ALKHIK-KMWLEDSQVGLPPYLMREIDLLLRLQHPNIMG
| | || .   .. . |.    .||| .|  .||.|. |
AIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIG
Kinase LmjF27.1940.AA CDK 331-369 40 0.005774 5.14 In-house 30-69 (284) Show / Hide 
Range on Protein: 331-369
Range on HMM: 30-69/284
Sequence Identity: 40% (17 aa)

RTYALKHIK---KMWLEDSQVGLPPYLMREIDLLLRLQHPNI
. .||| |.   .  .|.   |.|    ||| ||  | ||||
QIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL-HPNI
Kinase LmjF27.1940.AA CDK5 278-295 38 0.00847 4.13 In-house 1-18 (287) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/287
Sequence Identity: 38% (7 aa)

YTRVGRISQGVYGVVFRA
| .. .|  | ||.|..|
YEKMEKIGEGTYGTVYKA
Kinase LmjF27.1940.AA MAPK 356-374 45 0.009686 5.04 In-house 53-72 (328) Show / Hide 
Range on Protein: 356-374
Range on HMM: 53-72/328
Sequence Identity: 45% (9 aa)

REIDLLLRL-QHPNIMGALE
||| || .. .|.||.. |.
REIKLLRHFHHHENIIKLLD
Kinase LmjF27.1940.AA MAPK 278-296 47 0.010548 4.91 In-house 1-19 (328) Show / Hide 
Range on Protein: 278-296
Range on HMM: 1-19/328
Sequence Identity: 47% (9 aa)

YTRVGRISQGVYGVVFRAV
|. . .| || ||||. |.
YQILKPIGQGAYGVVCSAI
Kinase LmjF27.1940.AA CDK10 278-295 38 0.01132 4.82 In-house 1-18 (285) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/285
Sequence Identity: 38% (7 aa)

YTRVGRISQGVYGVVFRA
. .. |.  | ||.|.||
FEKLNRVGEGTYGIVYRA
Kinase LmjF27.1940.AA CDK4 278-295 50 0.019053 3.96 In-house 1-18 (290) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/290
Sequence Identity: 50% (9 aa)

YTRVGRISQGVYGVVFRA
|  |  | .| || |.||
YQCVAEIGEGAYGTVYRA
Kinase LmjF27.1940.AA PITSLRE 355-377 50 0.034444 4.03 In-house 48-71 (295) Show / Hide 
Range on Protein: 355-377
Range on HMM: 48-71/295
Sequence Identity: 50% (12 aa)

MREID-LLLRLQHPNIMGALELVL
.|||  .|  ||||||   .| |.
LREINMILMALQHPNIVNVKEIVM
Kinase LmjF27.1940.AA CDK7 278-295 27 0.074683 0.23 In-house 1-18 (288) Show / Hide 
Range on Protein: 278-295
Range on HMM: 1-18/288
Sequence Identity: 27% (5 aa)

YTRVGRISQGVYGVVFRA
|. .  |  | ...|..|
YEKIKHIGEGQFATVYKA
Kinase LmjF27.1940.AA CDK10 498-511 64 0.082643 1.77 In-house 75-88 (285) Show / Hide 
Range on Protein: 498-511
Range on HMM: 75-88/285
Sequence Identity: 64% (9 aa)

VFLVMDYCPYDLGS
.||||.||  || |
IFLVMQYCEQDLAS
Kinase LmjF27.1940.AA Pkinase_Tyr 354-369 47 7.601323 0.1 Pfam 50-66 (270) Show / Hide 
Range on Protein: 354-369
Range on HMM: 50-66/270
Sequence Identity: 47% (8 aa)

LMREIDLLLRL-QHPNI
.|||. ..  | .||||
FMREAKIMKQLGHHPNI