Gene LmjF21.1080 (L.major)

LmjF21.1080

Species: L.major
Alias: LmajK054, LmjF21.1080
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK5

Sequence

Name Sequence Type Origin Length Description Download
LmjF21.1080.AA Protein None 301 None Fasta, JSON
LmjF21.1080.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of LmjF21.1080.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF21.1080.AA CDK5 5-297 57 3.6e-172 548.75 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-287/287
Sequence Identity: 57% (169 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATI
||. |||||||||.|||||.  |   |||||.||||| ||||.||||||.|||||.|.||| | || ||| .||.|||..| |||||.|  ||..|...|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

QHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMA-TGTPLF
. ||  ||.|.||||.. |||||||||||||... ||||.|||| | | |||| .. |||||||||||||.|| .|  ..|.||.|||| ||| .| |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

AGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSN-NMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLEKLLRYEPSERITAADALNHPYF
 | .. |||.|||. .|||.   |||. . |. . |.   | .  . .. |...        ||   | |||.|.|...| .||.|..||.||||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMY--PAHQSWQQIV------PKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase LmjF21.1080.AA CDK 5-297 46 1.8e-170 549.8 In-house 1-284 (284) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-284/284
Sequence Identity: 46% (152 aa)

YERQEKIGEGTYGVVYKARDTSTS-----ATVALKRIRLDS-----EEEGVPCTAIREISLLKELRHENIVKLLDVCHSE-----------HRLTIVFEY
||. ||||||||||||||||. |        ||||.||...     |.||.|.|||||||||||| |.|||||.||||..           ..|..||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LDLDLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKE-----LKLGDFGLGRSFAI------PVRKFTNEVVTLWYRPPD
.| |||||.|          |...|. ||||...||.. ..||||||||.||..  |     ||..|||| | | |      |.|..|.||||||||.|.
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

VLLGSMQYG--PPVDVWSVGCIFSEMAT---GTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLG
.|||| .|.  .|.|.|||||||.||.|   . ||| |... ||| .|||..|||.  .||.. ..|.                                
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------------

CAGVDLLEKLLRYEPSERITAADALNHPYF
    |||.|.| |.|. ||.| .||.||||
----DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF21.1080.AA CDC2 5-297 49 1.5e-166 516.35 In-house 1-301 (301) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-301/301
Sequence Identity: 49% (153 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEG--VPCTAIREISLLKELR-HENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENG---N
|.. |||||||||||||..|. |   ||||.|||..|.||  || |||||||.||||. |.||||| || |. ..| .|||||| |||||.|....   .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFT--NEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEM
.. .... .|  .|.||.||||| ..||||||||.||... ..|..||||.| | ||.|. |   ||||||||.| .|||. .|  |||.||.||||.||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYP---NSNNMLSQPEFLQNFEPEWSNVLGSVPGYEK--LGCAGVDLLEKLLRYEPSERITA
   .|  |||.|.   ||| .|||.|||||.  ||.. |.|   |.  .. .  . . .. . ..       ..   |   |.|||...|.|.|. ||.|
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKK-------KNQSCLDPEGIDLLMQMLQYDPQKRISA

ADALNHPYF
 .||.||||
KEALQHPYF
Kinase LmjF21.1080.AA CMGC 5-297 27 2.1e-137 454.5 In-house 1-513 (513) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-513/513
Sequence Identity: 27% (140 aa)

YERQEKIGEGTYGVVYKARDTSTS--------------ATVALKRIRLDS---------EEEGVPCTAIREISLLKELR-----------------HENI
||  .||||||||||||.||. |                 ||.|.|...          |..|.|..|.|||..||.|.                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VKLLDVCHSEH-----------------RLTIVFEYLDLDLKKYLDRENG--------NLDAAT------------IQHFM------RDLLRGVA--FCH
|||.|......                  | .||||.| ||..|... ..        .|.               |..||      . .|||..  .||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

QRS--VLHRDLKPQNLLISREKEL--------------------KLGDFGLGRSFAIP---------------------VRKFTNEVVTLWYRPPDVLLG
..   ..||||||.|.||. ..||                    |..|||| |.. ..                     .| .|..|||.|||.| .|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

S---------MQYGPPVDVWSVGCIFSEMATG--------TPLFAGKND-----------ADQLMRIFRFLGTPN---------------NRVWPSMNQY
.         |.|..|.|.||||||| || ||         ||| |...            ||| .||. ||||.                . ||.|...
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNSNNMLS----------QPE-----------FLQNFEPEWSNVLGSVPG-----------------------------YEKLGCAGVDLLEKLLRYEPS
|. |....          ..|           | .   . |.|.    |                               ...   ..|||.|.|.|.|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

ERITAADALNHPYF
.||||..||.||||
KRITAEQALQHPYF
Kinase LmjF21.1080.AA PFTAIRE 5-297 47 3.2e-126 425.65 In-house 1-287 (287) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-287/287
Sequence Identity: 47% (141 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATI
||. || |||.|  |||..   .   |||| |||. .|||.|.||||| ||||.|.| ||| | |. | .  ||.||||.. ||..|.|. .| ..   .
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

QHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGTPLFA
. |.  |||| ..|||| ||||||||||||||   |||| |||| |   .| . . .||||||||||||||||  |   .|.| ||||| || .| |.| 
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GK-NDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQ--PEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLEKLLRYEPSERITAADALNHPYF
|  .  ||| .||. ||||.   ||   . || .    .      .. .  | . .. .|.       . ||. |.|..|| .|. |..|. ||||
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQW-PRIYYIPH-------AEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase LmjF21.1080.AA PCTAIRE 5-297 49 2.6e-125 422.62 In-house 1-291 (291) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-291/291
Sequence Identity: 49% (148 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATI
| . .| |||||  ||| |   |   |||| |||.  ||| |||||||.||||.|.| ||| | |. | .| ||.||||.| |||.|.|     ..   .
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

QHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGTPLFA
  |.  |||| |.||.| .||||||||||||  . |||| |||| |   .| . . .|||||||||||||.|| .|  ..|.| ||||| ||.|| ||| 
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP

GKN------DADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSN--VLGSVPGYEKLGCAGVDLLEKLLRYEPSERITAADALNHPY
|          |||  |||.|||| .. ||            | .|| .   |.. .  ..   |  .|.   . |||..||.||. .|. |..|..|||
GSTDSHYPGVKDQLHMIFRILGTPDEKTWP---------GVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPY

F
|
F
Kinase LmjF21.1080.AA CDK7 5-244 41 1e-112 301.57 In-house 1-244 (288) Show / Hide 
Range on Protein: 5-244
Range on HMM: 1-244/288
Sequence Identity: 41% (102 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIR-LDSEEE---GVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLD
||  ..||||....||||.|..|   || |.|. | . .|   |.  |||||| .|.|..|.|.. |.|.      .  ||...| ||          | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

AATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGT
 | |  .|  .|.|. .||.  .||||||| |||.. . .||..|||| |..  | | .|  ||| ||| |  | |  .||. ||.||||||| |    .
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPE
| . | .| ||| |||. ||||. . || | . .. . . ..|.
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPG
Kinase LmjF21.1080.AA PITSLRE 5-297 41 1.1e-107 364.06 In-house 1-295 (295) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-295/295
Sequence Identity: 41% (124 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLD--SEEEGVPCTAIREIS-LLKELRHENIVKLLDVC--HSEHRLTIVFEYLDLDLKKYLDREN---
..   .|.||||||||.|.|. |   |||||. ..   | || | |..|||. .|..|.|.|||... .          .|.||.. |||  ..  .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

GNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEM
       |  .|  |||||.. |   ..|||||  |||.| .  ||..||||.| .  |....|  ||||||| | .|||.  | .|||.||||||| |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

ATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGS-VPGYEKLGCAGVDLLEKLLRYEPSERITAADALNHP
 |. ||| ||.. ||...||  .|||. . ||  .  |....| .       |..   | | . .|. ...   | ||| ..| | | .|||| ||| ||
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNN-------FPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHP

YF
.|
WF
Kinase LmjF21.1080.AA S_TKc 5-297 28 2.9e-100 340.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-231/231
Sequence Identity: 28% (89 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDL---DLKKYLDRENGN---
||  .|||.|..|.|||.|...|   ||.|.|.         ....|||..||. .|.|||||.||... ..| .|.||.|    ||..|... ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGP-PVDVWSVGCIFSE
  ..  .....|. .......||.. ..||||||.|.|...  ..|..|||| | .       |  ..|.||..| ||    .||. ..|.||.|||. |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLEKLLRYEPSERITAADALN--
|..| |.|       |....|. .|                                                 . |...|.|...|..|.|| .||.  
MLCGYPPFP------QMQMMFKKIG----------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----HPYF
     ||.|
WDIKCHPWF
Kinase LmjF21.1080.AA Pkinase 5-297 31 8.9e-93 319.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAIR--EISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDL-----DLKKYLD-REN
|.. .|||.|..|.|||... .|. .||.|.|....|..... |..|  ||...|.|.|.|||.|.|..... .. .|.||..      ||. |.  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GNL--DAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKEL----KLGDFGLGRSF-AIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSV
|..  .  .....|. .|||...||.....||||||.|.||... ..    |..|||| . |   . . .|  ..|.||..| |..|.  |||.||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIFSEMATGTPLFAGK----NDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLEKLLRYEPSER
|||. ||..| |.| |.    | .||. .|.| .|.|. . ||  .  .... .  . .                .   ..  .. |.....|.. |..|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H------------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

ITAADALNHPYF
.||...|.||.|
PTAEQILQHPWF
Kinase LmjF21.1080.AA CDK4 5-229 48 3.2e-92 312.7 In-house 1-235 (290) Show / Hide 
Range on Protein: 5-229
Range on HMM: 1-235/290
Sequence Identity: 48% (115 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEE--GVPCTAIREISLLKELR---HENIVKLLDVCH------SEHRLTIVFEYLDLDLKKYLD
|.    |||| || ||.|||. |   ||||..|  ..||  |.|   |||||... |    | |||||.||||      .|  .|.|||  | ||. |||
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

RENG-NLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCI
.     . . ||.| |..||||| | |  .. ||||||||.|.......|| |||| | .     ..|  ||||||| | ||| |  |  ||| ||||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQM-ALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

FSEMATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPS
|.||    ||| |....||| .||   |.|    ||.
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPR
Kinase LmjF21.1080.AA CRK7 5-228 37 1.1e-87 297.58 In-house 1-278 (343) Show / Hide 
Range on Protein: 5-228
Range on HMM: 1-278/343
Sequence Identity: 37% (105 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSE---EEGVPCTAIREISLLKELRHENIVKLLDVCHS--------EHR--LTIVFEYLDLDLKKY
||. . ||||||| ||||....|   ||||..|.| |   .|| | |||||| .|..| |.|||.| ..  .        .|.     |||| | ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LDRENG---NLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPV--RKFTNEVVTLWYRPPDVLLGSMQY------
|  |..   .     . .||. || |.. ||.. .||||.|  |.|.    |.|. |||| | .      |..|| |.|||||||  |||  .|      
L--ESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHIL

--------------------------------GPPVDVWSVGCIFSEMATGTPLFAGKNDADQLMRIFRFLGTPNNRVWP
                                || .|.||.|||. | .|..|.| |.|  .||  |..  |.||  .||
KELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWP
Kinase LmjF21.1080.AA Pkinase_Tyr 5-148 28 2.4e-21 72.91 Pfam 1-157 (270) Show / Hide 
Range on Protein: 5-148
Range on HMM: 1-157/270
Sequence Identity: 28% (46 aa)

YERQEKIGEGTYGVVYKARDT----STSATVALKRIRLDSEEEGVPCTA------IREISLLKEL-RHENIVKLLDVCH-SEHR--LTIVFEYLDL-DLK
 .  .|.||| .|.|||.. .    .|  .|| | ..     ||    .      .||....|.| .|.|||.|. ||   .    . ||.||  . ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KYLDRE---NGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGL
.|| .    ...|.  .. .. ..  .| .. ...   ||||   | |.....  | .||||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase LmjF21.1080.AA TyrKc 5-297 20 1.9e-13 -5.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-297
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

YERQEKIGEGTYGVVYKARDTSTSATVALKRIRLDSEEEGVPCTAI-REISLLKEL--RHENIVKLLDVCHSE-------HRLTIVFEYLDL-DLKKYLD
 .  .|.||| .|.|||.. .    .|| | .. |.        .. ||......|  .|.|||.|. || ..       . | ||.|| .. |||.|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSF-----------AIPVRK--FTNEVVTLWYRPPDVLLGSMQY
.  ..|  ..  .|. .  .| .. |.. . ||||   | |.....  | .|||| |              . ...   .. .. .   .| ..     .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

GPPVDVWSVGCIFSEMAT-GTPLFAG-----KNDAD--QLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAG--
 .  |||| |    |. | | .   |     .....  .. .  . .  | |   | |                                .   .|    
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-------------------------------F--VCCPDEM

VDLLEKLLRYEPSERITAADALNHPYF
 .. ..  ...|..| | ..   | .|
YQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF21.1080.AA CDK7 271-297 33 4.4e-13 30.76 In-house 262-288 (288) Show / Hide 
Range on Protein: 271-297
Range on HMM: 262-288/288
Sequence Identity: 33% (9 aa)

VDLLEKLLRYEPSERITAADALNHPYF
.||.....  .|..|.|....|..|||
LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase LmjF21.1080.AA CDK4 270-297 50 1.2e-11 36.06 In-house 263-290 (290) Show / Hide 
Range on Protein: 270-297
Range on HMM: 263-290/290
Sequence Identity: 50% (14 aa)

GVDLLEKLLRYEPSERITAADALNHPYF
| |||.| |.|... |..|  .|.||||
GDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase LmjF21.1080.AA CRK7 271-297 44 1.6e-10 32.26 In-house 317-343 (343) Show / Hide 
Range on Protein: 271-297
Range on HMM: 317-343/343
Sequence Identity: 44% (12 aa)

VDLLEKLLRYEPSERITAADALNHPYF
.||| |.| . |. |.|| ..|.|..|
LDLLDKMLCLDPKKRFTAEECLQHDWF