Gene LmjF36.4250 (L.major)

LmjF36.4250

Species: L.major
Alias: LmajK066, LmjF36.4250
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF36.4250.AA Protein None 807 None Fasta, JSON
LmjF36.4250.kin_dom Protein Kinase Domain None 518 None Fasta, JSON

Protein domain

Protein domains of LmjF36.4250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF36.4250.AA CMGC 16-398 15 9.7e-70 228.05 In-house 1-368 (513) Show / Hide 
Range on Protein: 16-398
Range on HMM: 1-368/513
Sequence Identity: 15% (82 aa)

YIPNKVLGTGTYGQVIRCYD--------------NVTGKDVAVKVAQSDAAYRRSAL-------------NEISALLCLK---------------ENED-
|   |..| ||||.| .|.|              . |.. ||.|   ..  | . |.              ||. | .|.               ...  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

SVNILDSFEDAG-----------------HVCIVSELLDRNLFEVLRHRGFG-------PLSLRE------------VRQVA------LRVLSALA--SL
 |...|.| . .                 |...| |..| .|......  |        |||  .            ..           .| .|.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HNSG--YIHCDIKPENIMLRRSTPV-------SSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQLWRNTNSIDSLVGNT
|  .   ||.|.|||||..   . .       |.                                                                  
HSHWGNIIHRDLKPENILINHNCELITRMMWKSE------------------------------------------------------------------

HSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGNKGIESQERTQFNPD
                                                                                             .   ||.
---------------------------------------------------------------------------------------------D-W-NPC

ANPYRRTCLIDFGAVRRFNEN------------------------TYYDVQSLWYRAPEVLCGLP----------YTTAIDSWSVGCVLFELFTG-----
 .   |  ..|||  | ....                         . .|...||||||.|.| .          |||.|| |||||...|..||     
-QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLI

---KPFFPGESL-----------QHQLSLIVQ
   ||.|||.|            ..|| .|..
FRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFK
Kinase LmjF36.4250.AA S_TKc 16-533 13 1.9e-57 198.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-533
Range on HMM: 1-231/231
Sequence Identity: 13% (70 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDSVNILDSFEDAGHVCIVSELLDR---NLFEVLRHRGFGP----
|   ...| |..|.| .|... ||. ||.|.        .....||. |      .  |...|.|.| .|...| |..|    .||.....|| ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSD--SSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQLW
..  ..| ..  ...||. .|. | ||.|.|||||.| . .   .|  .. ..                                               
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------------------------------------------

RNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGNK
                                                                                                    
----------------------------------------------------------------------------------------------------

GIESQERTQFNPDANPYRRTCLIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTT-AIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
                                   .  . ..||.|||||   .|.. ..| ||.||.|.|...|.| ||      |. .. ...|    
-----------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----

AALTLGCLATQFQLPMVYVSHDARREHVRQWILSSREAGLQRWRKHQIQKLQEAHIAGNQQLWLHRTADVPNTKSEEDALLTATPYGESDVDGASEELEL
                                                                                                  . 
-------------------------------------------------------------------------------------------------SPE

LVDLVCDLLNPDESQRLSCTQALR-------HPFL
. |... .|. | ..|... .||.       ||..
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF36.4250.AA CLK 16-386 19 1.4e-45 134.22 In-house 1-249 (350) Show / Hide 
Range on Protein: 16-386
Range on HMM: 1-249/350
Sequence Identity: 19% (77 aa)

YIPNKVLGTGTYGQVIRCYDNVTGK-DVAVKVAQSDAAYRRSALNEIS-ALLCLKEN--------EDSVNILDSFED-AGHVCIVSELLDRNLFEVLRHR
|   ..|| || | | .| |.  ||  ||.|.  .   ||  |  ||.  .  ..|.        |... ..|.|.   ||.||| ||. ........  
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

G------FGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSS----DSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALK
.      . |. .. .|. |   ..|. .||  . .| | ||||| .     |.|    .. .| . .  . |                           
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF-----VDSRFTHFDCTFKYNHKKKIN---------------------------

LDSNANAHNQLWRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRN
                                                                                                    
----------------------------------------------------------------------------------------------------

DLRVNCNALGNKGIESQERTQFNPDANPYRRT-----CLIDFGAVR--RFNENTYYD-VQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPG
                  ... |    .|..      |.||||  .  ||     .. |..  ||||||  ||.. .  | ||.||.|||| ||  .|..
------------------KKS-NNCVCHYWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQT
Kinase LmjF36.4250.AA DYRK 16-146 38 3.3e-45 156.52 In-house 1-138 (320) Show / Hide 
Range on Protein: 16-146
Range on HMM: 1-138/320
Sequence Identity: 38% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKEN--EDSVNI---LDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPL-
|   ...| |..|||..|.|. |...||.|.  .  .. |.|..||. | .|...  .|. ..   .|.|   .|.||| |||. ||.|.|. ..| .. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLREVRQVALRVLSALASLHNS-GYIHCDIKPENIMLR
||. ||..|  .| .|  ||..  .||||.|||||||.
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLK
Kinase LmjF36.4250.AA Pkinase 16-398 16 9.1e-39 138.15 Pfam 1-229 (293) Show / Hide 
Range on Protein: 16-398
Range on HMM: 1-229/293
Sequence Identity: 16% (69 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYR---RSALN--EISALLCLKENEDSVNI---LDSFEDAGHVCIVSELLDR-----NLFEVLR
|   ...| |..|.| .|..  ||| ||||.   . .     .....  ||. .. |.    . ||   .|.||| .|...| |...       ||....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

---HRGFGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNA
   |..|  .| .|.. ... .|..|. .|. | ||.|.|||||.. .   ...                                              
TWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------------------------------------------

NAHNQLWRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVN
                                                                                                    
----------------------------------------------------------------------------------------------------

CNALGNKGIESQERTQFNPDANPYRRTCLIDFGAVRR--FNENTYYDVQ--SLWYRAPEVLC-GLPYTTAIDSWSVGCVLFELFTGKPFFPGE----SLQ
                         . ...|||  .      |. ...   ..||.||||.  | .|....| ||.||.|.|...|.| |||.    .  
-------------------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-H

HQLSLIVQ
 |. .|..
DQMQMICR
Kinase LmjF36.4250.AA HIPK 16-145 38 2.6e-37 114.71 In-house 1-134 (329) Show / Hide 
Range on Protein: 16-145
Range on HMM: 1-134/329
Sequence Identity: 38% (52 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLK-ENEDSVNI---LDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPLSL
|    .|| ||.|||..|    |.  ||.|.   .. | |   .|.| | ||. || |  ..   .. |... |.|.| |.|. ||.. ..   | || |
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

REVRQVALRVLSALASLHNSGYIHCDIKPENIML
. .| . . || ||. | . | || |.|||||||
KHIRPILQQVLTALMKLKELGLIHADLKPENIML
Kinase LmjF36.4250.AA DYRK2 16-152 35 4.3e-32 101.41 In-house 1-142 (318) Show / Hide 
Range on Protein: 16-152
Range on HMM: 1-142/318
Sequence Identity: 35% (51 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDS-----VNILDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPLS
|   .|.| | .|||..|||  |.. ||.|.      . . |. ||  |  ....        | .||.|   .|.||. |||. || | .. . |  .|
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVS
|..||  |  .| .|  ||    |||| |||||.|.  .. .
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSG
Kinase LmjF36.4250.AA DYRK 328-405 50 4.4e-32 112.9 In-house 148-225 (320) Show / Hide 
Range on Protein: 328-405
Range on HMM: 148-225/320
Sequence Identity: 50% (39 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
.||||     ..  |  .||  ||||||..|.|| .||| ||.||.| |||||.|.||||. ..|| .|..  | |..
VIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPK
Kinase LmjF36.4250.AA DYRK2 328-405 43 1.6e-29 92.88 In-house 145-223 (318) Show / Hide 
Range on Protein: 328-405
Range on HMM: 145-223/318
Sequence Identity: 43% (34 aa)

LIDFGAVRRFNE-NTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
.||||  .  ..   | ..||. |||||| .|..| .||| || ||.. ||.||.|.||||  . |. ..    | |..
VIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLGMPPK
Kinase LmjF36.4250.AA YAK 16-146 37 2.6e-27 89.55 In-house 1-140 (347) Show / Hide 
Range on Protein: 16-146
Range on HMM: 1-140/347
Sequence Identity: 37% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCL-----KENED----SVNILDSFEDAGHVCIVSELLDRNLFEVLRHRGF
||   .|| ||.|||. |  . |   .||||  .  ||   | |||  |  |      .|.      ....|.|    | |.| |.|  ||.| |    |
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

GPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLR
  .|   .||    .| ..  | |.  |||| |||||||.
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLC
Kinase LmjF36.4250.AA CAMK 21-145 16 5.3e-26 80.18 In-house 1-212 (425) Show / Hide 
Range on Protein: 21-145
Range on HMM: 1-212/425
Sequence Identity: 16% (36 aa)

VLGTGTYGQVIRCYDNVTG------------KDVAVKV-----AQSD------------------------AAYRRSALNEISALLCLKE------NEDS
.||.|..|.| .|..  |.            . ||.|.     ....                        .  |.. ..||. .  |..       .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNILDSFEDAGH-------------------VCIVS---ELLDRN-----LFEVLRHRGF-------------GPLSLREVRQVALRVLSALASLHNSGY
..... .||. .                   ...|    |. .       ||. .. .|              | .. ||.|..   ..||.. .|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHCDIKPENIML
.|.|.|||||.|
VHRDLKPENILL
Kinase LmjF36.4250.AA MAPK 345-405 44 5.9e-23 76.04 In-house 192-256 (328) Show / Hide 
Range on Protein: 345-405
Range on HMM: 192-256/328
Sequence Identity: 44% (29 aa)

VQSLWYRAPEVLCG---LPYTTAIDSWSVGCVLFELFT-GKPFFPGESLQHQLSLIVQHVGHPSQ
|   ||||||....     ||.|.| ||||| . |. | .||.|||.. ..|. ||.. .| ||.
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSE
Kinase LmjF36.4250.AA YAK 328-403 40 3.6e-21 68.33 In-house 149-224 (347) Show / Hide 
Range on Protein: 328-403
Range on HMM: 149-224/347
Sequence Identity: 40% (31 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHP
.||||         |  .|. .||.||.. . .|.|.|| || ||.. ||| | | ||| |   |.. |.   | |
IIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIFPGNSEYNQIKRIIDMLGYP
Kinase LmjF36.4250.AA DYRK1 328-417 38 4.7e-21 70.29 In-house 147-236 (321) Show / Hide 
Range on Protein: 328-417
Range on HMM: 147-236/321
Sequence Identity: 38% (35 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQAALTLGCLATQF
.||||.  . ..  |  .|| .||.|||| |..| .||| ||.||.| |. || | | | . . |.. ||  .| | .. .  .  | ..
IIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKY
Kinase LmjF36.4250.AA DYRK1 16-146 33 6.7e-20 66.17 In-house 1-138 (321) Show / Hide 
Range on Protein: 16-146
Range on HMM: 1-138/321
Sequence Identity: 33% (47 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDS------VNILDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPL
|  .  .| | .|||.. ||... . ||.|. .   ..   |. ||  || |  ..|       |..   |    |.|.| |||  ||...||   |   
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEI-RLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV

SLREVRQVALRVLSALASLHNSGY--IHCDIKPENIMLR
||  .|. |  .. ||  .       ||||.|||||.|.
SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC
Kinase LmjF36.4250.AA PRP4 328-388 50 8.1e-17 58.14 In-house 148-209 (320) Show / Hide 
Range on Protein: 328-388
Range on HMM: 148-209/320
Sequence Identity: 50% (32 aa)

LIDFGAVRRFNEN--TYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGES
..|||   . .||  | |  .|  |||||.. | ||  .|| ||||| |.||.|||  ||| .
MCDFGSASHIHENEITPY-LVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFPGKT
Kinase LmjF36.4250.AA HIPK 318-417 39 1.5e-16 48.21 In-house 137-236 (329) Show / Hide 
Range on Protein: 318-417
Range on HMM: 137-236/329
Sequence Identity: 39% (41 aa)

PDANPYRRTCLIDFGAVRRFNE---NTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQAALTLGCLA
|   || |   ||||    . .   |||  .|| .|||||.. |||.  ..|.|| |||. ||| | | .|| .   |   | |  . | .  |  .| .
PTRCPY-RVKVIDFGSASHVSKVVCNTY--LQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKK

TQF
..|
HRF
Kinase LmjF36.4250.AA PRP4 16-144 30 4.4e-13 44.3 In-house 1-138 (320) Show / Hide 
Range on Protein: 16-144
Range on HMM: 1-138/320
Sequence Identity: 30% (42 aa)

YIPNKVLGTGTYGQVIRCYDNVTGK-DVAVKVAQSDAAYRRSALNEISALLCLKEN----EDSVNIL---DSFEDAGHVCIVSELLDRNLFEVLRHRGFG
|  .   | | .. |.|| |.  |. .||.|.  .    ... | |.  |  | ..    .|   ..   ..|.   | |.| | .  || |||   | .
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

P-LSLREVRQVALRVLSALASLHNSGYIHCDIKPENIM
  |.|  ||  |   . ||  | .....| |||| ||.
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNIL
Kinase LmjF36.4250.AA CAMK 508-533 34 7.7e-09 23.87 In-house 400-425 (425) Show / Hide 
Range on Protein: 508-533
Range on HMM: 400-425/425
Sequence Identity: 34% (9 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
||.. .|..| ..|....|.|.||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF36.4250.AA CAMK 352-382 31 5.2e-08 21.15 In-house 288-332 (425) Show / Hide 
Range on Protein: 352-382
Range on HMM: 288-332/425
Sequence Identity: 31% (14 aa)

APEVLCG--------------LPYTTAIDSWSVGCVLFELFTGKP
||||| |               .|. ..| ||.|..|. . .|.|
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP
Kinase LmjF36.4250.AA Pkinase 508-533 30 1.6e-07 27.65 Pfam 268-293 (293) Show / Hide 
Range on Protein: 508-533
Range on HMM: 268-293/293
Sequence Identity: 30% (8 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
|.....|..| ..|....|.| ||..
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF36.4250.AA CMGC 504-533 33 4.2e-07 18.4 In-house 484-513 (513) Show / Hide 
Range on Protein: 504-533
Range on HMM: 484-513/513
Sequence Identity: 33% (10 aa)

ELLVDLVCDLLNPDESQRLSCTQALRHPFL
....||.. .|  | ..|... |||.||..
PQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF36.4250.AA MAPK 16-45 36 6.2e-07 19.78 In-house 1-36 (328) Show / Hide 
Range on Protein: 16-45
Range on HMM: 1-36/328
Sequence Identity: 36% (13 aa)

YIPNKVLGTGTYGQVIRCYDNV------TGKDVAVK
| . | .| | ||.|  ..|.       .|| ||.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK
Kinase LmjF36.4250.AA DYRK 502-533 28 1e-06 20.8 In-house 289-320 (320) Show / Hide 
Range on Protein: 502-533
Range on HMM: 289-320/320
Sequence Identity: 28% (9 aa)

ELELLVDLVCDLLNPDESQRLSCTQALRHPFL
. ....|..  .|. | ..|... |||.||..
DDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF36.4250.AA CLK 500-533 41 2e-06 14.4 In-house 317-350 (350) Show / Hide 
Range on Protein: 500-533
Range on HMM: 317-350/350
Sequence Identity: 41% (14 aa)

SEELELLVDLVCDLLNPDESQRLSCTQALRHPFL
..| . | ||.  .|  | |.|..| .|| ||| 
DPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase LmjF36.4250.AA MAPK 507-533 33 3e-06 17.22 In-house 302-328 (328) Show / Hide 
Range on Protein: 507-533
Range on HMM: 302-328/328
Sequence Identity: 33% (9 aa)

VDLVCDLLNPDESQRLSCTQALRHPFL
.||.. .|  | ..|..  .||.||..
IDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF36.4250.AA TyrKc 16-428 11 8e-06 -128.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-428
Range on HMM: 1-280/280
Sequence Identity: 11% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCL-KENEDSVNILDSFEDA-------GHVCIVSELLDR-NLFEVL-RHRG
   .|.|| | .|.| ..  .    .||||. ..||  |.  ..|.. .  | ....  |...    .        . ..|| |. .  .| . | .||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

FGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQL
   |....  . .. . .  . ||  ..|| |.   |... .                                                          
K--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------------------------------------

WRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGN
                                                                                                    
----------------------------------------------------------------------------------------------------

KGIESQERTQFNPDANPYRRTCLIDFGAVRRFNEN-------TYYDVQ---SLW------YRAPEVLCGLPYTTAIDSWSVGCVLFELFT-GKPFFPG--
                   .    |||  |   .         ||...   .          |||..    .||. | || | ...|.|| |..  ||  
-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMI

----------ESLQHQLSLIVQHV--------GHPSQAALTLGCLATQFQ--LPMVYVSHDA
          | ...   .   .          ..    . . | . .      .  . .. 
QQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF36.4250.AA YAK 504-533 30 1.2e-05 14.79 In-house 318-347 (347) Show / Hide 
Range on Protein: 504-533
Range on HMM: 318-347/347
Sequence Identity: 30% (9 aa)

ELLVDLVCDLLNPDESQRLSCTQALRHPFL
....|..  ||. .   | .  ||  |||.
DCFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase LmjF36.4250.AA MAPK 86-143 30 2.4e-05 14.21 In-house 91-148 (328) Show / Hide 
Range on Protein: 86-143
Range on HMM: 91-148/328
Sequence Identity: 30% (18 aa)

VCIVSELLDRNLFEVLRHRGFGPLSLREVRQVALRVLSA--LASLHNSGYIHCDIKPENI
..||.|| . .|  ... .   |||   ..     .| .  |  .|  . ||.|.||.||
IYIVMELMETDLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNI
Kinase LmjF36.4250.AA DYRK2 517-533 47 7.6e-05 11.33 In-house 302-318 (318) Show / Hide 
Range on Protein: 517-533
Range on HMM: 302-318/318
Sequence Identity: 47% (8 aa)

DESQRLSCTQALRHPFL
| |.|..  |||.||..
DPSERMTPSQALKHPWI
Kinase LmjF36.4250.AA PRP4 517-533 47 0.000158 12.59 In-house 304-320 (320) Show / Hide 
Range on Protein: 517-533
Range on HMM: 304-320/320
Sequence Identity: 47% (8 aa)

DESQRLSCTQALRHPFL
| . | .| .||.|||.
DPKKRITCNEALKHPFI
Kinase LmjF36.4250.AA DYRK1 508-533 38 0.002515 6.97 In-house 296-321 (321) Show / Hide 
Range on Protein: 508-533
Range on HMM: 296-321/321
Sequence Identity: 38% (10 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
||.  .|. |  ||..  .||.|.|.
DLIKRMLQYDPKQRITPYYALQHSFF
Kinase LmjF36.4250.AA HIPK 507-533 29 0.009163 3.98 In-house 303-329 (329) Show / Hide 
Range on Protein: 507-533
Range on HMM: 303-329/329
Sequence Identity: 29% (8 aa)

VDLVCDLLNPDESQRLSCTQALRHPFL
|..   ..  |  .|..  .||.||| 
VHVLKKMCTWDAHKRITPCEALNHPFV