Gene LmjF14.0830 (L.major)

LmjF14.0830

Species: L.major
Alias: LmajK068, LmjF14.0830
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF14.0830.AA Protein None 990 None Fasta, JSON
LmjF14.0830.kin_dom Protein Kinase Domain None 488 None Fasta, JSON

Protein domain

Protein domains of LmjF14.0830.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF14.0830.AA CMGC 463-805 17 2.4e-62 203.31 In-house 271-647 (513) Show / Hide 
Range on Protein: 463-805
Range on HMM: 271-647/513
Sequence Identity: 17% (86 aa)

YVVREVIGKGSFGTVLHCVD--------------QKYHEAVAVKVIRSGPYFESQGW-------------FEAQVVAHL--NNDPAL-----------QN
| . ..||.|..|.|  |.|               .. | ||.| |.. . .| |.               | .   ||  |.||              |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

LVVQLRKVFLWKG-----------------HMVLVFEPLSFSLYRLITLTK--YNG------------------------VSLDLTRKFAYQMIKVLL--
 .|.|. .|  |.                 |. |||| .  .||..|  ..  |.|                         .. . | ..||... |   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

VLEQHQPPIIHCDLKPENVLLRDPSRS------------------EVRVIDFGSACYQQQP-------------QWNPPPAQVVLPSTSPSSSSGPPWDS
 . .|   |||.||||||.|. .  ..                  .....|||.|..  ..             .                         
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKN-------------------------

VAEGASGGVKPTAAADDDDSSGPQSPPKGPQQRPQATAGSTTASTDAALASGVAAPTAEEAGTVKKASDAAPAVAAAAGTATGDDRGGDII--------M
                                                                                         .         .
-----------------------------------------------------------------------------------------VNKDDKPNRPY

PKYIQSRYYRSPEVILELG----------YTTAIDRWSLGCFLVEMHTG--------VPLFPGKNE-----------GDMVAYFTSILGPLPDYMI
  |...|.||.||..|  .          |||.|| ||.|| . || ||         |||||..|            |. .    .||. . .||
THYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMI
Kinase LmjF14.0830.AA S_TKc 463-950 16 6.4e-57 196.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 463-950
Range on HMM: 1-231/231
Sequence Identity: 16% (81 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHLNNDPALQNLVVQLRKVFLWKGHMVLVFEPLSF---SLYRLITLTKYNG
| . ..||||.||.|  |.. | .. ||.|.|.       . . | |.  .          .|.|  ||   .|. .|.| ..    .|...|   ...|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VSLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSACYQQQPQWNPPPAQVVLPSTSPSSSSGPPWDSVAEGASGGV
     .   .|...||... |  . .|   |||.||||||.|| .    .. ..|||.|.                                        
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE----HIKICDFGLARQL--------------------------------------

KPTAAADDDDSSGPQSPPKGPQQRPQATAGSTTASTDAALASGVAAPTAEEAGTVKKASDAAPAVAAAAGTATGDDRGGDIIMPKYIQSRYYRSPEVILE
                                                                                     .. ...|..|||.  
-----------------------------------------------------------------------------------TTFCGTPWYMAPEVL--

LGYTT-AIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMIAASPKRKQLYYTCPSDPSTNSGGGESAHGVATVGIGPAEDAPPGLTPMS
 ||.. ..| ||.|| | || .| |.||     .| . |  |.                                                         
-GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------------------------------------------------

SAPGHAMGSPFFLRTPRVEGEGAAAAAVAGSSSNSPPLSLEEILGVHKGGPRGCRAGQPGHDEAAYEVFCDFIHKLLQYDPRKRVSCQQAIQ-------H
                                                                  . ..||| |.||.||.|| .. .| |       |
-----------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PFL
|..
PWF
Kinase LmjF14.0830.AA DYRK 463-619 41 5.5e-56 192.31 In-house 1-159 (320) Show / Hide 
Range on Protein: 463-619
Range on HMM: 1-159/320
Sequence Identity: 41% (67 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHLNND-PALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLTKYNGV-
| . |.||||||| |  | |.| .| ||.|.||. ..|  |.  | .   .||.  |  .  .|..   | ...|. .|||.|| .|| ..  .. .|. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDP-SRSEVRVIDFGSACYQQQ
|| |.||||.|. . |..|...   ||||||||||..|..| ..|.. ||||||.|.  |
SLNLVRKFAQQILTCLKFLHKNE-NIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ
Kinase LmjF14.0830.AA DYRK2 463-619 41 7.1e-52 166.8 In-house 1-156 (318) Show / Hide 
Range on Protein: 463-619
Range on HMM: 1-156/318
Sequence Identity: 41% (65 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHL-NNDPALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLTKYNGVS
| . ||||||||| |. | | |... ||.|.||    | .|   | ..  |.  .|.  .  .| ..  |   .|. ..|| || .|| .|   ...| |
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSACYQQQ
| | |.||..... |  | ..   ||||||||||.||. . || . |||||| |.  |
LQLVRRFAHSILQCLRFLHKNN--IIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQ
Kinase LmjF14.0830.AA DYRK1 463-619 44 2.5e-48 166.88 In-house 1-158 (321) Show / Hide 
Range on Protein: 463-619
Range on HMM: 1-158/321
Sequence Identity: 44% (70 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHLNN-DPALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLTKYNGVS
| .   ||||||| |    |.. .| ||.|.|.    |  |   | ...  .|. |.  .  .|.|.. | .. |. |||| ||. || |.  |.. |||
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSACYQQQ
| |||||| ||.. || .      ||||||||||.||. | || ...|||||.|   |
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQ
Kinase LmjF14.0830.AA YAK 463-616 38 3.6e-39 130.48 In-house 1-157 (347) Show / Hide 
Range on Protein: 463-616
Range on HMM: 1-157/347
Sequence Identity: 38% (62 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHLNN--DPALQN---LVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLTKY
|.|  . |.| || |  |      | .||||| . . .  |.  |.|.   ||   ||   |    .. .   | .| |. |||| || .|| ..  .|.
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

NGVSLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSACY
 | |  | | .  |    . |||  |  ||||||||||..|. | . |...|||||.|.
CGFSFQLIRQWTKQILDGMCVLENKQ--IIHCDLKPENIMLCKPNKPEIKIIDFGSSCQ
Kinase LmjF14.0830.AA DYRK 740-818 52 2.1e-34 120.62 In-house 163-242 (320) Show / Hide 
Range on Protein: 740-818
Range on HMM: 163-242/320
Sequence Identity: 52% (42 aa)

KYIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMIAAS-PKRKQLYYTC
.|||||.||.||||| . | .||| ||||| |.|..|| |||||.|| |. |..  .||. |  || ..  .||. ...|
TYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC
Kinase LmjF14.0830.AA CLK 463-601 26 4.9e-33 95.84 In-house 1-150 (350) Show / Hide 
Range on Protein: 463-601
Range on HMM: 1-150/350
Sequence Identity: 26% (41 aa)

YVVREVIGKGSFGTVLHCVDQKY-HEAVAVKVIRSGPYFESQGWFEAQ-VVAHLNND--PALQNL--VVQLRKVFLW-KGHMVLVFEPLSFSLYRLITLT
|..  . | | ||.|. |.| |.    ||.|.||.   .  . | | . .  ..|.   | ....  .....  |   .||. .||| .  |.| ..  .
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

K------YNGVSLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDP
.      | .  .| .|..||| .. .  |.  .  ..| |||||| .. |.
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMK--LTHTDLKPENICFVDS
Kinase LmjF14.0830.AA DYRK1 740-815 55 4.7e-29 98.85 In-house 162-237 (321) Show / Hide 
Range on Protein: 740-815
Range on HMM: 162-237/321
Sequence Identity: 55% (42 aa)

KYIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMIAASPKRKQLY
.|||||.||||||.|.. | .||| ||||| ||||||| ||| |.|| | .     .||  |..||  .|| .. .
QYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYF
Kinase LmjF14.0830.AA HIPK 463-614 37 7.8e-29 87.54 In-house 1-152 (329) Show / Hide 
Range on Protein: 463-614
Range on HMM: 1-152/329
Sequence Identity: 37% (57 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWFEAQVVAHLNNDPALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLTKYNGVSL
| | |..|.| || |  |  .  .| ||.|...  ||.  ||  | .. . | .  | .  .|    .|  | |. |||| |   ||      |.    |
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

DLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRS--EVRVIDFGSA
   |    | .. |. | .    .|| ||||||..| ||.|    |.|||||||
KHIRPILQQVLTALMKLKELG--LIHADLKPENIMLVDPTRCPYRVKVIDFGSA
Kinase LmjF14.0830.AA DYRK2 741-798 58 1.8e-28 89.45 In-house 162-219 (318) Show / Hide 
Range on Protein: 741-798
Range on HMM: 162-219/318
Sequence Identity: 58% (34 aa)

YIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILG
|||||.||.||||| . | .||| ||.|| ..|. ||.||||| ||.|  |..  .||
YIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLG
Kinase LmjF14.0830.AA YAK 740-786 55 1.5e-22 73.13 In-house 164-210 (347) Show / Hide 
Range on Protein: 740-786
Range on HMM: 164-210/347
Sequence Identity: 55% (26 aa)

KYIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNE
.|||.|.|||||.|.   |.|.|| ||||| ..|   |.|.|||  |
TYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIFPGNSE
Kinase LmjF14.0830.AA MAPK 586-785 17 2.6e-21 70.28 In-house 138-239 (328) Show / Hide 
Range on Protein: 586-785
Range on HMM: 138-239/328
Sequence Identity: 17% (38 aa)

IIHCDLKPENVLLRDPSRSEVRVIDFGSACYQQQP-------------QWNPPPAQVVLPSTSPSSSSGPPWDSVAEGASGGVKPTAAADDDDSSGPQSP
.||.||||.|.|.   .  .... ||| |.   .              |                                                   
VIHRDLKPSNILVN--ENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQ---------------------------------------------------

PKGPQQRPQATAGSTTASTDAALASGVAAPTAEEAGTVKKASDAAPAVAAAAGTATGDDRGGDIIMPKYIQSRYYRSPEVILE---LGYTTAIDRWSLGC
                                                                 |  |.  |.||.||..|     .||.|.| ||.||
--------------------------------------------------------------KMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGC

FLVEMHT-GVPLFPGKN
 . || | . ||||||.
IFAEMLTDRKPLFPGKD
Kinase LmjF14.0830.AA DYRK1 894-950 50 1.7e-20 68.26 In-house 265-321 (321) Show / Hide 
Range on Protein: 894-950
Range on HMM: 265-321/321
Sequence Identity: 50% (29 aa)

LEEILGVHKGGPRGCRAGQPGHDEAAYEVFCDFIHKLLQYDPRKRVSCQQAIQHPFL
|.|||||. ||| | |.| |||  . |  | | |...|||||..|..  .|.||.|.
LHEILGVETGGPGGRRKGEPGHSVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase LmjF14.0830.AA Pkinase 744-950 17 1.9e-20 73.41 Pfam 174-293 (293) Show / Hide 
Range on Protein: 744-950
Range on HMM: 174-293/293
Sequence Identity: 17% (38 aa)

SRYYRSPEVIL-ELGYTTAIDRWSLGCFLVEMHTGVPLFPGK----NEGDMVAYFTSILGPLPDYMIAASPKRKQLYYTCPSDPSTNSGGGESAHGVATV
...|..||||.   .|....| ||.|| | || .| |.|||.    |  |. . .  |.|| ... .  .  .   . . . . .               
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------

GIGPAEDAPPGLTPMSSAPGHAMGSPFFLRTPRVEGEGAAAAAVAGSSSNSPPLSLEEILGVHKGGPRGCRAGQPGHDEAAY---EVFCDFIHKLLQYDP
                                                                          . | .  .   | ..||| ..|..||
--------------------------------------------------------------------------F-HWTF-HNWSEECKDFIKWCLCKDP

RKRVSCQQAIQHPFL
 || ...|. |||..
KKRPTAEQILQHPWF
Kinase LmjF14.0830.AA PRP4 463-614 31 1.6e-19 68.21 In-house 1-154 (320) Show / Hide 
Range on Protein: 463-614
Range on HMM: 1-154/320
Sequence Identity: 31% (49 aa)

YVVREVIGKGSFGTVLHCVDQKYHE-AVAVKVIRSGPYFESQGWFEAQVVAHLNND---PALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLI-TLTKY
| |   .|.| |..|  | ||      ||.|.||. .     |  |  .   ||.    .     .|..  .| .. || ||||..| .|  ..    | 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

NGVSLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSA
 | .|.  | .|.|.   |  | . .  |.| |.|| |.|    |..    .|||||
VGLHLKAVRSYAQQLFLALKHLKKCN--ILHADIKPDNILVNE-SKNTLKMCDFGSA
Kinase LmjF14.0830.AA Pkinase 463-615 28 4.1e-19 68.67 Pfam 1-160 (293) Show / Hide 
Range on Protein: 463-615
Range on HMM: 1-160/293
Sequence Identity: 28% (48 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQG---WF--EAQVVAHLNNDPALQNLVVQLRKVFLWKGHMVLVFEPLSFSLYRLITLT--
|.. ..||.||||.| .|..... . ||||.|.     ...    .   |.|. ..| | |     .|.|. .|  |.|. .|.| .   || .. |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPN----IVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDY

----KYNGV--SLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEV----RVIDFGSAC
    .....  | .  ....||... |  .  |.  |||.||||||.|.   .. ..    ...|||.|.
ISTWRHGCFYFSEWECKFYMYQILRGLEYC--HSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAK
Kinase LmjF14.0830.AA CLK 742-812 39 1.3e-18 51.78 In-house 208-283 (350) Show / Hide 
Range on Protein: 742-812
Range on HMM: 208-283/350
Sequence Identity: 39% (30 aa)

IQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILG-PLPDYMIAASP----KRK
...| || |||||.||. .  | || || |.|  ||. ||.. .. .  |    |.| |.|  || ..     |.|
VSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQK
Kinase LmjF14.0830.AA HIPK 741-815 38 1.5e-18 54.54 In-house 163-237 (329) Show / Hide 
Range on Protein: 741-815
Range on HMM: 163-237/329
Sequence Identity: 38% (29 aa)

YIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMIAASPKRKQLY
|.|||||| ||.|| | .  ..| ||||| . | . | ||.|| .| | . |.    .   .... |  | ....
YLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFF
Kinase LmjF14.0830.AA DyrkP 741-805 47 6.5e-17 51.6 In-house 165-229 (323) Show / Hide 
Range on Protein: 741-805
Range on HMM: 165-229/323
Sequence Identity: 47% (31 aa)

YIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMI
|.||| || ||||.   |   || ||||| | |. ||  ||   |   ..|    |.||.|..|.
YVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGLLARVIGIIGPFPEWMM
Kinase LmjF14.0830.AA PRP4 740-805 43 6.9e-16 54.69 In-house 164-229 (320) Show / Hide 
Range on Protein: 740-805
Range on HMM: 164-229/320
Sequence Identity: 43% (29 aa)

KYIQSRYYRSPEVILELGYTTAIDRWSLGCFLVEMHTGVPLFPGKNEGDMVAYFTSILGPLPDYMI
.| .||.||.||.|.   |  .|| || || | |. ||  .||||   .|   |. . | .|  ||
PYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFPGKTNNHMLKLFMDYKGKMPNKMI
Kinase LmjF14.0830.AA DYRK 892-950 35 3.7e-14 49.56 In-house 264-320 (320) Show / Hide 
Range on Protein: 892-950
Range on HMM: 264-320/320
Sequence Identity: 35% (21 aa)

LSLEEILGVHKGGPRGCRAGQPGHDEAAYEVFCDFIHKLLQYDPRKRVSCQQAIQHPFL
... .... ....| | | . |.|. . .. | ||| |.||.||.||....|| |||..
PKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF14.0830.AA CMGC 923-950 50 1.4e-13 40.05 In-house 486-513 (513) Show / Hide 
Range on Protein: 923-950
Range on HMM: 486-513/513
Sequence Identity: 50% (14 aa)

FCDFIHKLLQYDPRKRVSCQQAIQHPFL
. |.. |.||||| || ...|| |||..
AIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF14.0830.AA YAK 920-950 51 2.3e-13 41.35 In-house 317-347 (347) Show / Hide 
Range on Protein: 920-950
Range on HMM: 317-347/347
Sequence Identity: 51% (16 aa)

YEVFCDFIHKLLQYDPRKRVSCQQAIQHPFL
...| |||  ||| .||.|.. .|| ||||.
RDCFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase LmjF14.0830.AA DyrkP 586-616 54 3.7e-13 39.0 In-house 127-157 (323) Show / Hide 
Range on Protein: 586-616
Range on HMM: 127-157/323
Sequence Identity: 54% (17 aa)

IIHCDLKPENVLLRDPSRSEVRVIDFGSACY
.|||||||||.|..  .. .|..|||||.|.
LIHCDLKPENILMKSYPKCQVKIIDFGSSCF
Kinase LmjF14.0830.AA MAPK 924-950 40 2.7e-10 31.57 In-house 302-328 (328) Show / Hide 
Range on Protein: 924-950
Range on HMM: 302-328/328
Sequence Identity: 40% (11 aa)

CDFIHKLLQYDPRKRVSCQQAIQHPFL
.|.. |.|. || || . ..|.|||..
IDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF14.0830.AA CLK 923-950 53 5.2e-10 25.46 In-house 323-350 (350) Show / Hide 
Range on Protein: 923-950
Range on HMM: 323-350/350
Sequence Identity: 53% (15 aa)

FCDFIHKLLQYDPRKRVSCQQAIQHPFL
. | | |.| ||| ||..|..| |||| 
LFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase LmjF14.0830.AA PRP4 925-950 46 1.9e-09 30.81 In-house 295-320 (320) Show / Hide 
Range on Protein: 925-950
Range on HMM: 295-320/320
Sequence Identity: 46% (12 aa)

DFIHKLLQYDPRKRVSCQQAIQHPFL
|.. |.|. || ||..| .| .|||.
DLLDKCLMLDPKKRITCNEALKHPFI
Kinase LmjF14.0830.AA DYRK2 921-950 40 3.4e-08 22.38 In-house 289-318 (318) Show / Hide 
Range on Protein: 921-950
Range on HMM: 289-318/318
Sequence Identity: 40% (12 aa)

EVFCDFIHKLLQYDPRKRVSCQQAIQHPFL
| | ||| . .. || .| . .|| .||..
ENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase LmjF14.0830.AA DyrkP 922-950 37 7.6e-07 17.84 In-house 295-323 (323) Show / Hide 
Range on Protein: 922-950
Range on HMM: 295-323/323
Sequence Identity: 37% (11 aa)

VFCDFIHKLLQYDPRKRVSCQQAIQHPFL
.| ||....|| |  .| . . |.|||..
MFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase LmjF14.0830.AA MAPK 463-494 28 5e-06 16.46 In-house 184-221 (328) Show / Hide 
Range on Protein: 463-494
Range on HMM: 184-221/328
Sequence Identity: 28% (11 aa)

YVVREVIGKGSFGTVLHCVDQK------YHEAVAVKVI
|.  . ||.|..|.|  ..|..      . . ||.| |
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI
Kinase LmjF14.0830.AA TyrKc 463-689 13 0.000522 -157.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 463-689
Range on HMM: 1-280/280
Sequence Identity: 13% (39 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVIRSGPYFESQGWF-EAQVVAHL--NNDPALQNLVVQLRKVFLWK-------GHMVLVFEPLSF-SLYRL
 .  ...| | ||.| ...     . ||||.....     .    ||..  .|  ...      .|.|  | . .       . . .|.|  .  .|   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHP-----NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

ITLTKYNGVSLDLTRKFAYQMIKVLLVLEQHQPPIIHCDLKPENVLLRDPSRSEVRVIDFGSACYQQQP-------QWNPP----PAQVVLP--------
.  .. . ....   .|..|  .    |...  ..|| ||   |.|. ..    |.. ||| . .           .   .     .  .||        
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

--STSPSSSS----------------GPPWDSVAEGASGGVKPTAAADDDDSSGPQSPPKG------------------------PQQRPQATAGSTTA
      .. |                ..|.  ...     .... .  . .. .   .|.                         | .||  ..     
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF14.0830.AA HIPK 923-950 32 0.002821 5.62 In-house 302-329 (329) Show / Hide 
Range on Protein: 923-950
Range on HMM: 302-329/329
Sequence Identity: 32% (9 aa)

FCDFIHKLLQYDPRKRVSCQQAIQHPFL
| .   |..  |. ||..  .|..||| 
FVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase LmjF14.0830.AA CLK 605-614 70 0.011401 3.02 In-house 185-194 (350) Show / Hide 
Range on Protein: 605-614
Range on HMM: 185-194/350
Sequence Identity: 70% (7 aa)

EVRVIDFGSA
...|||||||
HICVIDFGSA
Kinase LmjF14.0830.AA DyrkP 463-494 25 0.10024 0.68 In-house 1-32 (323) Show / Hide 
Range on Protein: 463-494
Range on HMM: 1-32/323
Sequence Identity: 25% (8 aa)

YVVREVIGKGSFGTVLHCVDQKYHEAVAVKVI
| . | .|   |   . | |..    . .|.|
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKII