Gene LmjF33.1830 (L.major)

LmjF33.1830

Species: L.major
Alias: LmajK070, LmjF33.1830
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
LmjF33.1830.AA Protein None 957 None Fasta, JSON
LmjF33.1830.kin_dom Protein Kinase Domain None 300 None Fasta, JSON

Protein domain

Protein domains of LmjF33.1830.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF33.1830.AA DYRK2 83-382 46 1.5e-141 463.28 In-house 1-318 (318) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-318/318
Sequence Identity: 46% (147 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKANNFFPMT
||||. .|.| ||||.|. ||     ||.|||||. . ..||  |||.|.|    |. . . .|.| | | ||.|.||  |||. |||| .| |.|   .
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVK-NMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELANGDP
|.|.|  |. .|  | || ..||.|||||||||||.   .| .|||| ||  |.    .|||||||||||||||   ||..||| ||||||. ||  | |
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

VFPGEDEKDQLGCIMEYLGPPPQSFVEIS---SARRRREFFD--------------ERYKPRPRTTCKGKQREPGSRSLAKFVSVSEDDDFLSFVRLFLQ
 ||||.|.||..|.|| || ||..|.. .     .||. ||.              ... |. ..  .|| | |||.|.....  .||..|. |..  ..
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFE

WEPSKRVPPREAMKHRWI
|.||.|  |..| || ||
WDPSERMTPSQALKHPWI
Kinase LmjF33.1830.AA DYRK 83-382 45 5.4e-133 448.14 In-house 1-320 (320) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-320/320
Sequence Identity: 45% (145 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKANNFFPM-
||||. .|.| ||||.|. ||    .||.|.|||. . ..||  ||..|.. |. ||   | .|.| | |..|.|.||  |||  |||| || |.| .  
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

TLSLIRSIAARMLVTLTFLARE-NIVHCDLKPENILLRDN-DPSVVKVIDLGSASFDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELANG
.|.|.|..|  .|. | ||... ||.|||||||||.|..  ..| .|||| ||..|  . .|||||||||||||||   .|..||| ||.|||| ||  |
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG

DPVFPGEDEKDQLGCIMEYLGPPPQSFVEISSARRRREFFDE------------RY------KPRPRTTCKGKQREPGSRSLAKFVSVSEDDDFLSFVRL
 | ||||.| ||| ||||.||.||. ... .. ||...|||.            ..       |..  | .|. | ||.|..  .    .|..|. |.. 
WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQ-CDDHQFKDFIKK

FLQWEPSKRVPPREAMKHRWI
 |||.|.||. | .|..| |.
CLQWDPHKRITPSQALQHPWF
Kinase LmjF33.1830.AA CMGC 83-382 18 8.3e-91 298.57 In-house 1-513 (513) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-513/513
Sequence Identity: 18% (97 aa)

YEILKELGSGAFGQVFKAID--------------HLDSSIVAVKMIRNQRKILQQAE-------------QEIRMLQHVN----------DRDPKGLYG-
|||.| .|.|..|.|.|..|              | .  |||.| |.|.     ||               ||..|.|.|          | || .    
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRD-DPDNKHHN

-IVRMTDNFKFRG-----------------HTCISYELLGSNLYEHLKANN--FFP------------------------MTLSLIRSIAARMLVTLT--
 ||.. | |....                 | ..  |... .||. .| |.  . .                        ... .|| ..  .|  |   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FLAREN--IVHCDLKPENILLRDNDPS------------------VVKVIDLGSASFDVKN------------------------MYTYIQSRFYRAPEV
.. . .  |.|.||||||||. .|  .                  ..|..| |.| .  ..                        ...|...|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

IMEQK----------YDKAIDWWSFGCILCELANG--------DPVFPGEDE-----------KDQLGCIMEYLGPPPQSFVEISS-----ARRRREFFD
..  |          |...|| ||.|||. |. .|        .| |||..|            ||| .|.. ||.|. .. . .      ... .|...
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

ERYKPRPRT-------------TC------------KGKQREPGSRSLAKFVSV-------------------------------SEDDDFLSFVRLFLQ
   .|.  .              .            ..... .  ..| .. .                                 .|.... ..   ||
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQ

WEPSKRVPPREAMKHRWI
..|.||  . .|..| ..
YDPDKRITAEQALQHPYF
Kinase LmjF33.1830.AA DYRK1 83-320 44 1.1e-82 281.04 In-house 1-238 (321) Show / Hide 
Range on Protein: 83-320
Range on HMM: 1-238/321
Sequence Identity: 44% (106 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKANNFFPMT
|||   .| |.|||| || ||..   ||.|.|.|..  ..||  |||.|  .| .|.   | ||..   |.|| | |. .|||  |||. |.  .|  . 
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LSLIRSIAARMLVTLTFLARE--NIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELANGD
| |.| .|  |. .| |..    .|.|||||||||||.    | .|.|| ||.    . .| ||||||||.|||... .|| ||| || |||| |.  |.
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

PVFPGEDEKDQLGCIMEYLGPPPQSFVEISSARRRREFFD
|.| | .| ||.  |.| || ||. ....  | . . .|.
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQ--APKAHKYFE
Kinase LmjF33.1830.AA S_TKc 83-382 25 1.1e-73 251.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-231/231
Sequence Identity: 25% (80 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGS---NLYEHLKANNF-
||||...|.||||.|.|.... .  |||.|.|.      .....||..|..       .   ||.. | |   .| ..  |...    .|....| ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

---FPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVKNMYTYIQSRFYRAPEVIMEQKYDK-AIDWWSFGCILC
   ||..   .|.... ..  | .. . .|.|.||||||||| .    ..|..| |.| .     .|.. ...|.||||.   .|.| ..||||.|||| 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELANGDPVFPGEDEKDQLGCIMEYLGPPPQSFVEISSARRRREFFDERYKPRPRTTCKGKQREPGSRSLAKFVSVSEDDDFLSFVRLFLQWEPSKRVPPR
|.. | | ||      |.  ... .|                                                   ......|.|  ||..|.||    
EMLCGYPPFP------QMQMMFKKIG---------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-

EAMK-------HRWI
||..       | |.
EALQDEWDIKCHPWF
Kinase LmjF33.1830.AA YAK 83-303 42 1.4e-71 242.38 In-house 1-225 (347) Show / Hide 
Range on Protein: 83-303
Range on HMM: 1-225/347
Sequence Identity: 42% (96 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDR-DPKGLY---GIVRMTDNFKFRGHTCISYELLGSNLYEHLKANNF
| .|  || | |||| |    .   ..||| | |    .|||  ||..|.  |.. || .      |.|| | | .. | |. .|.|  |||| || |.|
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

FPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELAN
  .  .|||      |  .  |.  .|.|||||||||.|.  .   .|.|| ||.    | .|||||.|.||.||.|.   |  .|| || |||. ||  
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL

GDPVFPGEDEKDQLGCIMEYLGPPP
| |.|||  | .|.  | . || ||
GLPIFPGNSEYNQIKRIIDMLGYPP
Kinase LmjF33.1830.AA HIPK 83-321 38 5.5e-63 197.02 In-house 1-239 (329) Show / Hide 
Range on Protein: 83-321
Range on HMM: 1-239/329
Sequence Identity: 38% (94 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKANNFFPMT
||.|  || | |||| |.  .  . .||.|...|.     | . |...|. . . ..   | .||. . |. . |||. .|.|  |||. .| |.| |. 
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE-YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

LSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDND--PSVVKVIDLGSASFDVKNMY-TYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELANG
|  || |    |  |  |    ..| |||||||.| |    |  ||||| ||||   |    ||.|||.|||||.|.  .. ...| || ||.. ||  |
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG

DPVFPGEDEKDQLGCIMEYLGPPPQSFVEISSARRRREFFDE
 | .|| || ||   | .  . | .. ..  .|..   |||.
WPLYPGADEYDQIRYICQTQHLPHEHLLH--AACKKHRFFDR
Kinase LmjF33.1830.AA Pkinase 83-382 25 2.1e-61 215.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-293/293
Sequence Identity: 25% (83 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQ-----EIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELL-GS----NLYEH
|.|.. .|||.||.|.|.... .. ||||| |. ...  .. ..     ||......|       . |||. | |  ..| ..  |.. |      |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LK---ANNFFPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSV---VKVIDLGSA----SFDVKNMYTYIQSRFYRAPEVIM-EQKYD
..    ..|  ..   .....  .|  | .. ...|.|.||||||||.  |.. .   ||..| |.|          |.|.  ...|.|||||.  |.|.
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

KAIDWWSFGCILCELANGDPVFPGE----DEKDQLGCIMEYLGPPPQSFVEISSARRRREFFDERYKPRPRTTCKGKQREPGSRSLAKFVSVSEDDDFLS
...|.||.|||| |...| | |||.    .  ||. .| . .|||. .  . .. ..... |   . .                  .... .  ......
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------------F-HWTF-HNWSEECKD

FVRLFLQWEPSKRVPPREAMKHRWI
|..  |.. |.||  ......| |.
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF33.1830.AA CLK 83-224 34 5.5e-51 150.7 In-house 1-159 (350) Show / Hide 
Range on Protein: 83-224
Range on HMM: 1-159/350
Sequence Identity: 34% (55 aa)

YEILKELGSGAFGQVFKAIDHLDS-SIVAVKMIRNQRKILQQAEQEIR-MLQHVNDR-DPKGLYG--IVRMTDNFKF-RGHTCISYELLGSNLYEHLKAN
|||.. ||.|.|| |.. .||  . . ||.| |||  |   .|  ||.  ....|   || . |   ...| | |..  || ||. ||.| ..|. .|.|
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

N------FFPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDN-----DPSV
|      . |  .. ||..|.  .  . ||    ..| |||||||.. |      |...
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTF
Kinase LmjF33.1830.AA DyrkP 83-283 37 1.3e-45 147.75 In-house 1-205 (323) Show / Hide 
Range on Protein: 83-283
Range on HMM: 1-205/323
Sequence Identity: 37% (77 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKAN----NF
| |.  ||| || .  .  |     .. .|.| | .    |.  ||..|. .|         ..|. | |  . |  |  |||  ||||  | |      
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

FPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELAN
   |.  .  |   .|..| ..    ..||||||||||..      ||.|| ||. |    .  |.||| |||||||.  |||  || || |||| ||  
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWT

GDPVF
|  .|
GNVLF
Kinase LmjF33.1830.AA PRP4 83-300 36 2.3e-41 143.74 In-house 1-222 (320) Show / Hide 
Range on Protein: 83-300
Range on HMM: 1-222/320
Sequence Identity: 36% (81 aa)

YEILKELGSGAFGQVFKAIDHLDSS-IVAVKMIRNQRKILQQAEQEIRMLQHVNDR--DPKGLYGIVRMTDNFKFRGHTCISYELLGSNLYEHLKAN-NF
|..    |.| |. | .. |       ||.| |||     .  . |. .||  ||   |.   . .||| . |..| | |. .| .  || | ||     
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

FPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSAS-FDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELA
  . |  .|| |  ... |. | . ||.| |.|| |||   .  .. | .| ||||      .  | .||||||||.|.  .|| .|| || || | ||.
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNESK-NTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY

NGDPVFPGEDEKDQLGCIMEYLG
 |   |||    . |  .|.| |
TGKIMFPGKTNNHMLKLFMDYKG
Kinase LmjF33.1830.AA Ciliate-E2 83-382 15 7.7e-40 134.43 In-house 1-365 (365) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-365/365
Sequence Identity: 15% (68 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVA---------------------VKMIRNQRKILQQAEQEIRMLQHVNDRDPKGLYG---------------IV
|...| .|.|.||.|.|. . ..   .|                     . | ... . ..| .|||.... .|. .    |                |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-F----YKKINEKNILEQLNHPNII

RMTDNFK--FRGHTCISYELLGS-NLYEHLKANNFF---------PMTLSLIRSIAARMLV---------------TLTFLAREN-IVHCDLKPENILLR
.| . |.   . .  .  |..   .|....| |. .         ..|.  |. | .  |                 | .|  .| |.| |.||||||. 
KMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-

DNDPSVVKVIDLGSASFDVKN-----------MYTYIQ------------------------SRFYRAPEVIMEQK---------YDKAIDWWSFGCILC
      .|.||.| . .  ..           .|.. .                        .  | |||... .|         ||...|.||.|.|| 
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

ELANGDPVFPGEDEKDQLGCIMEYLGPPPQSFVEISSARRRREFFDERYKPRPRTTCKGKQREPGSRSLAKFVS------------------------VS
|.  | | |                                                           . .                            .
EMLFGKPPF-----------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKK

EDDDFLSFVRL----FLQWEPSKRVP-PREAMKHRWI
 ...   . .      || .|.||   . ....| |.
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF33.1830.AA CLK 225-382 28 3.8e-21 59.5 In-house 186-350 (350) Show / Hide 
Range on Protein: 225-382
Range on HMM: 186-350/350
Sequence Identity: 28% (47 aa)

VKVIDLGSAS---FDVKNMYTYIQSRFYRAPEVIMEQKYDKAIDWWSFGCILCELANGDPVFPGEDEKDQLGCIMEYLG-PPPQSFVEISS-ARRRREFF
..||| |||    ||    .| ...| |||||||..  .    | ||.|||| ||  |. .|.. |... |  . . .| | ||.    .   .  ...|
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYF

-DERYKPRPRTTCKGKQREPGSRSLAKFVSVS--EDDDFLSFVRLFLQWEPSKRVPPREAMKHRWI
 . |   .. .. .|.        | .. .    | . .   .|  |  .||||.  ..| .|.. 
YHNRLDWDW-HNSDGRYVMENCKPLKQYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase LmjF33.1830.AA TyrKc 83-382 19 1.4e-10 -51.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 83-382
Range on HMM: 1-280/280
Sequence Identity: 19% (64 aa)

YEILKELGSGAFGQVFKAIDHLDSSIVAVKMIRNQRKILQQAEQEIRMLQHV--NDRDPKGLYGIVRMT-DNFKFRGHTCISYELLGS-NLYEHLKANNF
 . .|.||.||||.|.|..       |||||...    ..   .|.|.. ..  .      |||...    ||   .  .|  |.    .| ..|...  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

FPMTLSLIRSIAARMLVTLTFLARENIVHCDLKPENILLRDNDPSVVKVIDLGSASFDVKNM--------YTYI----QSR-----FYRAPEVIMEQKYD
   ...   |..        .|.. |..| ||   |.|. .|   .||. | |  | |...         |       ...        |||.|.. |. 
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFG-LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAIDWWSFGCILCELANGDPVFPGEDEKDQLGCIMEYLG-----PPPQSFVEISSARRRREFFDE----RYKPRPRTTCKGKQREPGSRSLAKFVSVSED
 . | ||||  . |.                 . . | |      ..|  .|   ...|..  ..                            |  |   
TKSDVWSFGVCMWEIFT--------------YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------F--VCCP

DDFLSFVRLFLQWEPSKRVPPREAMKHRWI
|.  .  .   . .|..|   .|   |. .
DEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF33.1830.AA Pkinase_Tyr 83-116 36 1e-06 23.04 Pfam 1-38 (270) Show / Hide 
Range on Protein: 83-116
Range on HMM: 1-38/270
Sequence Identity: 36% (14 aa)

YEILKELGSGAFGQVFKAIDH----LDSSIVAVKMIRN
 ...|.||.||||.|.|.. .     .   |||||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE
Kinase LmjF33.1830.AA DyrkP 351-382 37 6.4e-05 11.39 In-house 292-323 (323) Show / Hide 
Range on Protein: 351-382
Range on HMM: 292-323/323
Sequence Identity: 37% (12 aa)

EDDDFLSFVRLFLQWEPSKRVPPREAMKHRWI
.|  |. |||  || .  .|   .||..| |.
DDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase LmjF33.1830.AA DYRK1 348-382 28 0.00025 10.55 In-house 287-321 (321) Show / Hide 
Range on Protein: 348-382
Range on HMM: 287-321/321
Sequence Identity: 28% (10 aa)

SVSEDDDFLSFVRLFLQWEPSKRVPPREAMKHRWI
||..   |   ..  ||..| .|. | .|..| ..
SVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase LmjF33.1830.AA YAK 355-382 39 0.000874 8.3 In-house 320-347 (347) Show / Hide 
Range on Protein: 355-382
Range on HMM: 320-347/347
Sequence Identity: 39% (11 aa)

FLSFVRLFLQWEPSKRVPPREAMKHRWI
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FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase LmjF33.1830.AA PRP4 363-382 45 0.009044 6.07 In-house 301-320 (320) Show / Hide 
Range on Protein: 363-382
Range on HMM: 301-320/320
Sequence Identity: 45% (9 aa)

LQWEPSKRVPPREAMKHRWI
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LMLDPKKRITCNEALKHPFI
Kinase LmjF33.1830.AA HIPK 363-382 35 0.021543 2.79 In-house 310-329 (329) Show / Hide 
Range on Protein: 363-382
Range on HMM: 310-329/329
Sequence Identity: 35% (7 aa)

LQWEPSKRVPPREAMKHRWI
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CTWDAHKRITPCEALNHPFV