Gene LmjF10.0490 (L.major)

LmjF10.0490

Species: L.major
Alias: LmajK078, LmjF10.0490
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF10.0490.AA Protein None 388 None Fasta, JSON
LmjF10.0490.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of LmjF10.0490.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF10.0490.AA MAPK 33-320 41 7.69999999999e-128 431.01 In-house 1-328 (328) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-328/328
Sequence Identity: 41% (135 aa)

YTLLKILGMGAYGIACSCLDGD------TGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFF-HHENLLNVVNILPPLK----REYHSFEDVYVVTPLMDV
|..|| .| ||||. ||. |        .|.|| |||  ..|... . ||..||| ..|.| ||||  .. .|. | .    .. ..|.|.|.|..||. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DMNVVLRSRQVLEESHMQYFVYQILRG--LKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYS--------------ELTDYVITRWYRPP
|.. ...|.| |.. |.|||.||||||  |||.||||| ||||||.|.. |  |.||| ||||.||.|  |.               .|.|| ||||| |
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

ELLLE--NTNYSTAVDIWSVGCIFAEMYN-RKPVFPGRNTMDQLRMIAQHIGKPPASIVEHRE-A------LEKLNELPDGSL-NIPKLVPGLA--GNTE
|..|    ..|..|||.||||||||||.. ||| |||....||. .| . .|.|.   ..  .        .. |. ||     .  |. |.     | .
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

GIDFLSKMWTLDPSKRPTAADMLAHPYL
 ||.|.|| ..||.|| |... |.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF10.0490.AA ERK 33-257 47 8.60000000001e-112 377.7 In-house 1-238 (307) Show / Hide 
Range on Protein: 33-257
Range on HMM: 1-238/307
Sequence Identity: 47% (114 aa)

YTLLKILGMGAYGIACSCLDGD-----TGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFH-HENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVV
| ..| .|.||||. ||. |       ||.|| |||  ..| .  . || |||| ..|.|. |||. .  .|. |  .|  ...|.|.|..||. |.  .
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE--QYNDIYCVEELMETDLHQI

LRSRQVLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYSE--------LTDYVITRWYRPPELLLENTNYSTAV
 .|.| |.. | |||.||||.||||.||||| |||||| |.  |  | ||| ||||.| .|. |.|        .|.||.|||||.||..| ...|..|.
INSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAM

DIWSVGCIFAEMYNRKPVFPGRNTMDQLRMIAQHIGKP-P
||||.|||||||..|||.|||.....|.. | | ||.| .
DIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHS
Kinase LmjF10.0490.AA CMGC 33-320 23 1.4e-111 368.13 In-house 1-513 (513) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YTLLKILGMGAYGIACSCLD--------------GDTGEKVSIKKCRDVFRDVEDGK----------RVLREIDMMRFF-----------------HHEN
|. .| .| |.||. ..| |               .|.|.| ||| . .| . |..|          | |||| ... .                 ||.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LLNVVNILPPLK-REYHS---------FEDVYVVTPLMDVDMNVVLRSRQ---------VLEESH------------MQYFV------YQILRGLK--YL
...  .|. . . . ...         |...| |. .|| |   .... |          |.| |             .||.      ||||||||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAN--VAHRDLKPANLVTNISCEL--------------------KIIDFGLSRSVDVPYSE---------------------LTDYVITRWYRPPELLL
||..  . ||||||.|.  |  |||                    ||.||||.|..... ..                     .|.|| |||||.||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

ENTNYS---------TAVDIWSVGCIFAEMYNR--------KPVFP-----------GRNTMDQLRMIAQHIGKPPASIVEH----------REALEKLN
  ..|.         |..|.|||||||||||..        || ||           |... ||| .| . .|.|. .. .            |   . .
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMI

ELPDGSL---------------------------NIPKLVPGLA----------------------------------------GNTEGIDFLSKMWTLD
.||.  .                             ..  . .                                          . ..||.|.|| ..|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PSKRPTAADMLAHPYL
|.||.||.. |.|||.
PDKRITAEQALQHPYF
Kinase LmjF10.0490.AA ERK5 33-320 41 8.7e-93 314.57 In-house 1-295 (295) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-295/295
Sequence Identity: 41% (123 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVVLRSRQV
|  .  .| ||||. ||     .|..| |||    |  |   || .||. ..| |.|.|.. . .|| | |  |  . |||||  ||. |.  .. | | 
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMP-KVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSR-----SVDVPYSELTDYVITRWYRPPELLLENTNYSTAVDIWSVGCIF
.   |. ||.|||||||||.|||.| ||||||.||. |  ||||| |||. |     | |     .|.|| ||||| |||..   .|  |.|.|||||||
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIF

AEMYNRKPVFPGRNTMDQLRMIAQHIGKPPASIV-----EHREALEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMWTLDPSKRPTAADMLAHPYL
 ||  |. .|||.| ..||..| . .| ||. ..     .|  .  . |  .    .. |. |.      ..| |..|   .||.| |..  | ||.|
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKA--DRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase LmjF10.0490.AA p38 33-262 43 2.6e-92 312.97 In-house 1-229 (289) Show / Hide 
Range on Protein: 33-262
Range on HMM: 1-229/289
Sequence Identity: 43% (101 aa)

YTLLKILGMGAYGIACSCLDGDTGEK---VSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVVLRS
|  |. .| ||||  |.  | .||.|   | ||| .  | .... ||  ||.   .  .||| .   ..  |  ..  .|.|||.||..|. | | ....
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

RQVLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYSELTDYVITRWYRPPELLLENTNYSTAVDIWSVGCIFAE
 . | . | |. |||||||||| |||.. |||||| |.  |  |||.| ||||.|. |   .|.|.|| ||||| || .|    |  .||||||||| ||
QR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCD---DEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAE

MYNRKPVFPGRNTMDQLRMIAQHIGKPPASIVE
.  ... ||| . .|||. | . .|.|.. ...
LITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQ
Kinase LmjF10.0490.AA nmo 37-320 41 2.3e-90 278.05 In-house 5-292 (292) Show / Hide 
Range on Protein: 37-320
Range on HMM: 5-292/292
Sequence Identity: 41% (121 aa)

KILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVVLRSRQVLEES
. .| ||.|.  |  |   | .| .||  .|| ..   ||| ||. |. ||.|.| |   .|| |.. ..  |...|||| ||  |.  .. | | |   
RPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHKDF--FQEIYVVTELMQSDLHKIIVSPQHLSSD

HMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYS-ELTDYVITRWYRPPELLLENTNYSTAVDIWSVGCIFAEMYNRKP
|.. |.||||||||||||||. |||.|| ||. |  | ||| |||| |  .   | ..|  |.| .|| ||.|.    |. |||||||||||||.  |. 
HVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRI

VFPGRNTMDQLRMIAQHIGKPPASIVEHREALE-KLNELPDGSLNIPKL--VPGLAG----NTEGIDFLSKMWTLDPSKRPTAADMLAHPYL
.|  .. ..|| || . .| |  |. . . | |   . .  ...  |.|  . .|.     . | .. |..|   ||.||  . | ||||||
LFQAQSPIQQLQMITDLLGTP--SMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase LmjF10.0490.AA ERK7 33-320 38 3.4e-84 286.02 In-house 1-292 (292) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-292/292
Sequence Identity: 38% (116 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFH-HENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVVLRSRQ
| ..| || |||||    .|  |.. | .||  | ||.  |  |  ||| ... || |.|.. ..|...      .   |.|.|   |. |.. | |  .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIR-----ADNDRDIYLVFEFMETDLHAVIRKGN

VLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPY------SELTDYVITRWYRPPELLLENTNYSTAVDIWSVGC
.|.. | || .||.|| .||.||.|| ||||||.|.  .  | .|. |||| ||.            ||.|| ||||| || ||  ..|  .|| ||.||
ILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGC

IFAEMYNRKPVFPGRNTMDQLRMIAQHIGKPPASIVEHREA------LEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMWTLDPSKRPTAADMLAHPY
| .||   ||.|||  ||.|.  | . |.|| .  .|  .       ||..|. .  .|.  ...|     ...|| | ..  . | || || . |.|||
ILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLD--QMMP--QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPY

L
 
V
Kinase LmjF10.0490.AA S_TKc 33-320 27 3.9e-84 286.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDV---DMNVVLRS
|..|...| ||.|  . | . .||..| ||. .         ....|||....  ||.|. .   .           ...|.|. ..|    |.  ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKK

RQV------LEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYSELTDYVITRWYRPPELLLENTNYST-AVDIWS
|.       . | | ....|||...|.|.|| .. ||||||.|.  .   ..||.||||.| .       | .. |.||..||.|     |.. ..|.||
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWS

VGCIFAEMYNRKPVFPGRNTMDQLRMIAQHIGKPPASIVEHREALEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMWTLDPSKRPTAADMLA------
.|||..||. ..| ||      |. |. ..||                                     |..||..|... ||.||||| . |.      
CGCILYEMLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYL
 ||..
CHPWF
Kinase LmjF10.0490.AA ERK1 33-320 43 1.9e-82 280.19 In-house 1-289 (289) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-289/289
Sequence Identity: 43% (128 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDVDMNVVLRSRQV
|| |. .| ||||. || .|  ....| |||    |      .| |||| ..  |.|||..|. .|.        .. |||.|  ||. |.  .|.. | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDII--RADTIEQMRDVYIVQCLMETDLYKLLKT-QH

LEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYSE---LTDYVITRWYRPPELLLENTNYSTAVDIWSVGCIFAE
|   |. ||.|||||||||.||||| ||||||.||. |  |.||| |||| |  |        ||.|| ||||| ||..|    |  ..|||||||| ||
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE

MYNRKPVFPGRNTMDQLRMIAQHIGKPPASIVE---HREALEKLNELPDGS-LNIPKLVPGLAGNTEGIDFLSKMWTLDPSKRPTAADMLAHPYL
|   .|.|||.  .|||  |   .| |    ..    . | . |  ||  . .   .| |        .|.| || |  | || |  . ||||||
MLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFP--KADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase LmjF10.0490.AA CDK 33-320 31 3.8e-79 252.85 In-house 1-284 (284) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-284/284
Sequence Identity: 31% (101 aa)

YTLLKILGMGAYGIACSCLDGDTG-----EKVSIKKCRDVF---RDVEDGKR--VLREIDMMRFFHHENLLNVVNILPPLKREY---HSF-EDVYVVTPL
|  |. .| |.||.   . | .||     . | .|| |      .. ..|     .||| ...   |.|  ..  . .  ....   ...   .| | . 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MDVDMNVVLRSRQVLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCE-----LKIIDFGLSRSVDV------PYSELTDYVITRWYRPPEL
|| |   ...          . . .|.|||| |.|| .. ||||||.|.  |   |     ||| ||||.|   .      |  ..|  |.|.|||.|||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

LLENTNYS--TAVDIWSVGCIFAEMYN---RKPVFPGRNTMDQLRMIAQHIGKPPASIVEHREALEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMWT
||  ..||  |..|.||||||||||..   ||| |||..  ||| .| . .| |  ..    . |                           |.|.|| .
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKMLC

LDPSKRPTAADMLAHPYL
.||.|| .| . | |||.
YDPKKRISAEQALQHPYF
Kinase LmjF10.0490.AA Pkinase 33-320 26 1.4e-75 262.25 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-293/293
Sequence Identity: 26% (83 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLR--EIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDV-----DMNV
|......| |..|  . | . .||..| .|. . . .. .  .. .|  || .|. ..|.| .    .            ..|.|.....      |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-------KDHIYMVMEYCEGGLYVMDLFD

VLR--SRQVL--EESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCEL----KIIDFGLSRSV-DVPYSELTDYVITRWYRPPELLLENTNYST
...  .. ..  .| . . ..|||||||.|.|| .. ||||||.|.  .  ...    ||.||||.. .   ..| .|... |.||..||...... |..
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

AVDIWSVGCIFAEMYNRKPVFPGR----NTMDQLRMIAQHIGKPPASIVEHREALEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMWTLDPSKRPTAA
.||.||.|||..||....| |||.    | .||. ||..  |.|. .  .        . ...    .   .   . . |..||.......||.|||||.
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAE

DMLAHPYL
. | ||..
QILQHPWF
Kinase LmjF10.0490.AA MAPK-Unclassified 33-186 42 1.7e-61 210.65 In-house 1-159 (575) Show / Hide 
Range on Protein: 33-186
Range on HMM: 1-159/575
Sequence Identity: 42% (68 aa)

YTLLKILGMGAYGIACSCLDGDT-GEKVSIKKCRDVFRDVEDGKRVLREIDMMRFFHHENLLNVVNILPPLKREYHSFEDVYVVTPLMDV---DMNVVLR
|.. | .| ||||. |   |  . . .| |||   .| .. | |||||||   |   |.|.... .|. .   .   | |.|.|. .|     |.  ...
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

SRQ-VLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSV
|.|  ... | ||| |||||||||||||...||||||.||  |  | ..| |||.|||.
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSI
Kinase LmjF10.0490.AA MAPK-Unclassified 192-257 37 1.9e-28 99.71 In-house 404-500 (575) Show / Hide 
Range on Protein: 192-257
Range on HMM: 404-500/575
Sequence Identity: 37% (36 aa)

ELTDYVITRWYRPPELLLENTNYSTAVDIWSVGCIFAEMYNR-----------KPVFPGRN--------------------TMDQLRMIAQHIGKPP
..| || ||||| ||..| . .|.|.|||||.||||||| ..           .| |||..                      ||. ||    | ||
HMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPP
Kinase LmjF10.0490.AA TyrKc 33-320 21 4e-13 -10.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-320
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

YTLLKILGMGAYGIACSCLDGDTGEKVSIKKCRDVFRDVEDGKRVLREIDMMRFF--HHENLLNVVNILPPLKREYHSF---EDVYVVTPLMDV-DMNVV
 ||.|.|| ||.|. . .      ..| .|....        .  .||. .|. .  ||.|... . .    .|    |   | ...|. .|.  | .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYMPHGDLKDY

LRSRQV-LEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVP---------YSE----LTDY-VITRWYRPPELLLEN
||...  |  ... .| .|| .|  |||| |. ||||   |   .     || |||||| ..           |.      ... .  ||. .|| .  |
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--N

TN-YSTAVDIWSVGCIFAEMYNRKPVFPGR-----NTMDQLRMIAQHIGKPPASIV----EHREALEKLNELPDGSLNIPKLVPGLAGNTEGIDFLSKMW
.. ..|. |.|| |    |.. .    .        . ....   .. . .|                                     .|  .  .. |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F--VCCPDEMYQIMKQCW

TLDPSKRPTAADMLAHPYL
  ||..||| ..   | ..
HEDPEDRPTFSEI--HECF
Kinase LmjF10.0490.AA p38 294-320 55 7.6e-10 29.53 In-house 263-289 (289) Show / Hide 
Range on Protein: 294-320
Range on HMM: 263-289/289
Sequence Identity: 55% (15 aa)

IDFLSKMWTLDPSKRPTAADMLAHPYL
|| | ||  ||| || ||.. ..|||.
IDLLEKMLELDPDKRITAEEAMQHPYF
Kinase LmjF10.0490.AA ERK 290-320 48 6.9e-09 29.42 In-house 277-307 (307) Show / Hide 
Range on Protein: 290-320
Range on HMM: 277-307/307
Sequence Identity: 48% (15 aa)

NTEGIDFLSKMWTLDPSKRPTAADMLAHPYL
| ..|| |.|| . ||.|| |... |.|||.
NPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase LmjF10.0490.AA MAPK-Unclassified 289-320 53 8.2e-09 27.46 In-house 544-575 (575) Show / Hide 
Range on Protein: 289-320
Range on HMM: 544-575/575
Sequence Identity: 53% (17 aa)

GNTEGIDFLSKMWTLDPSKRPTAADMLAHPYL
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GNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase LmjF10.0490.AA Pkinase_Tyr 33-222 25 1e-06 22.83 Pfam 1-199 (270) Show / Hide 
Range on Protein: 33-222
Range on HMM: 1-199/270
Sequence Identity: 25% (53 aa)

YTLLKILGMGAYGIACSCLDG----DTGEKVSIKKCRDVFRDVED--GKRVLREIDMMRFF-HHENLLNVVNILPPLKREYHSFED--VYVVTPLMDV-D
 |..| || ||.|  . .       .|. .| .|....   . |.   .  .||. .|. . ||.|... . .        .  |   .|.|...|   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT------DQGEPNQIYIVMEYMPHGD

MNVVLRS----RQVLEESHMQYFVYQILRGLKYLHSANVAHRDLKPANLVTNISCELKIIDFGLSRSVDVPYSELTD-YVIT------RWYRPPELLLEN
.   ||.    .| |  ...  . .|| .|. ||.| |  ||||   |   . .   || ||||.| .   |.. .  .. .      .|. .|| . ..
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI---YNDDYYYRKRGGGKLPIKWM-APECINYG

TNYSTAVDIWS
  ..|. |.||
K-FTTKSDVWS
Kinase LmjF10.0490.AA Pkinase_Tyr 301-320 40 6.241465 0.39 Pfam 253-270 (270) Show / Hide 
Range on Protein: 301-320
Range on HMM: 253-270/270
Sequence Identity: 40% (8 aa)

WTLDPSKRPTAADMLAHPYL
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WHYDPEDRPTFSEI--HEQL