Gene LmjF19.1440 (L.major)

LmjF19.1440

Species: L.major
Alias: LmajK080, LmjF19.1440
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF19.1440.AA Protein None 363 None Fasta, JSON
LmjF19.1440.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of LmjF19.1440.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF19.1440.AA MAPK 30-318 41 1e-140 473.78 In-house 1-328 (328) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-328/328
Sequence Identity: 41% (138 aa)

YDLVKVVGFGACGTVCSAVANG------SGERVAIKRLSRVFGDLREGKRILREMEIMTSL-KHNNLIRLHHFMRP------QSKETFEDIYLVMDLYDT
|...| .|.|| |.||||. .       .|..||||..||.| ..   ||..||  ..  . .|.| |.| . ..|       |.| |.|||.||.| .|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLNRIIRSRQKLTDEHLQYFMIQAFRG--LHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLAR--DDQ-------VMS----SSDLTQYVVTRWYRPP
||..||.|.|.|.|.| |||| |  ||  | |.||| | ||||||||.||| .| | ||||||||  |..       ..     . ..|.||.||||| |
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVLGMG--SNQYTSAVDVWSLGLIFAELMV-GRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLS-S-EAKAFILSQ---PHRPALSFRDLFSM----ATE
|.. ..  .. || |||.||.| ||||..  .. |.||.||| |. .|...||.|| ....... | .|. .| |    |..|. .....|.     |. 
EIM-LNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP

EATDLLSKLLVFHPARRLTAKQVMEHPYF
.| |||.|.||| | .|.|... ..||||
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF19.1440.AA ERK 30-318 43 3.7e-131 442.03 In-house 1-307 (307) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-307/307
Sequence Identity: 43% (135 aa)

YDLVKVVGFGACGTVCSAVANG-----SGERVAIKRLSRVFGDLREGKRILREMEIMTSLK-HNNLIRLHHFMRPQSKETFEDIYLVMDLYDTDLNRIIR
| ..| .|.|| |.||||. ..     .|..||||  ...| .... ||.|||  ..  .| | |.| |.. |.| |.| ..|||.| .| .||| .||.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

SRQKLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLAR----DDQVMSSS---DLTQYVVTRWYRPPEVLGMGSNQYTSAVD
|.| |.|.| |||| |  .|| |.|||.|.||||||||.||| .| | ||||||||    . |  ...   ..|.||.|||||.||..    . ||.|.|
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIM-LSWQKYTKAMD

VWSLGLIFAELMVGRALLPGTDYIGQLVMIVNLLGSP-SIDDMEFL-SSEAKAFILSQPH--RPALSFRDLFSMAT--EEATDLLSKLLVFHPARRLTAK
.|| | ||||.. .. |.|| ||..|.  | ...|.| | .|..   | .|. .| ..|.  ||. .. ..|. |    .| |||.|.||| |  |.|..
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVE

QVMEHPYF
.  |||||
ECLEHPYF
Kinase LmjF19.1440.AA CMGC 30-318 23 3.9e-113 373.31 In-house 1-513 (513) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-513/513
Sequence Identity: 23% (121 aa)

YDLVKVVGFGACGTVCSAVA--------------NGSGERVAIKRLSRVFGDLREGK----------RILREMEIMTSLK-----------------HNN
|. .|..| |. |.|....               . ..|.||||.....| . ...|          |.||| .|.  |.                 |||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LIRLHHFMRPQ-SKET-----------FEDIYLVMDLYDTDLNRIIRSRQ---------KLTDEH------------LQYFM------IQAFRGLH--YL
...|. . ..  |. .           |...|||... |.|| ..|.. |         .|.. |             .|||       | .|||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAK--VMHRDLKPSNLLVNADCAL--------------------AICDFGLARDDQVMS--------------------SSDLTQYVVTRWYRPPEVLG
||..  ..||||||.|.|.| .| |                     ||||||||   . |                    .  .|.||||||||.||.| 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

MGS--------NQYTSAVDVWSLGLIFAELMVG--------RALLP-----------GTDYIGQLVMIVNLLGSPS---------------IDDME----
  .        ..||...|.||.| ||||.. |        . | |           |...| || .|...||.|.                ...     
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------FLSSEAKAFILS---QPHRPALSFRDLFSM-----------------------------------ATEEATDLLSKLLVFHP
                  ..|. |. .| |    | .|  ....||                                     ....| |||.|.|.. |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ARRLTAKQVMEHPYF
..|.||.| ..||||
DKRITAEQALQHPYF
Kinase LmjF19.1440.AA p38 30-318 42 6.4e-111 374.79 In-house 1-289 (289) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-289/289
Sequence Identity: 42% (126 aa)

YDLVKVVGFGACGTVCSAVANGSGER---VAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRP--QSKETFEDIYLVMDLYDTDLNRIIRS
|  .. || || |.||.|.. ..|..   ||||.|.| | .    ||. ||.     ..| | | |     |  .| . |.|.|.|. . ..|||.|...
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

RQKLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIF
 |.|.|.| |.   |  ||| | ||| . ||||||||. || || | | ||||||    .  ...|.||.||||| ||..      || .||.||.| | 
-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR----HCDDEMTGYVATRWYRAPEIMLNWMH-YTQTVDIWSVGCIM

AELMVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSE-AKAFILSQPHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTAKQVMEHPYF
|||. ||.| ||.|.| ||  |....|.|.   .. ..|| |...| | | .|   |...|..|.  | ||| |.|.  | .|.||.. |.||||
AELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase LmjF19.1440.AA nmo 31-318 43 4.4e-105 324.17 In-house 2-292 (292) Show / Hide 
Range on Protein: 31-318
Range on HMM: 2-292/292
Sequence Identity: 43% (127 aa)

DLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQSKETFEDIYLVMDLYDTDLNRIIRSRQKLTD
.  . .|.|| | | |     .| |||.|..  || .|   ||. ||. .. . ||.| . .   ..|  |. |..|| | .|   || .|| | |.|. 
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQHLSS

EHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIFAELMVG
.|.. |. |  ||| |||||...|||.|| |||||..| | ||||||||  .   | ..|| ||| .|| ||.| ||. .||||||.|| | |||||.  
DHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEIL-MGARHYTSAVDIWSVGCIFAELLGR

RALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFSMAT-----EEATDLLSKLLVFHPARRLTAKQVMEHPYF
| |      | || ||..||| ||..|| .    ||| .| .||.|  ..  |. ..       || .||...|.| | .|. .|. ..||| 
RILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPP-CLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase LmjF19.1440.AA ERK5 30-318 39 1.2e-91 310.78 In-house 1-295 (295) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-295/295
Sequence Identity: 39% (118 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQS-KETFEDIYLVMDLYDTDLNRIIRSRQKL
|. .  .| || | ||||.    |..||||..   |  . . || .||. |.   .|.|.| ..  ..|.     . |.| |.|| . ||  || | | .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

TDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMSSSD----LTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIF
| ||. ||. |  ||| |.|||.|.||||||||||||  | | | |||.||    .|. .    .|.|| ||||| ||.. . |..|| |.|||| | ||
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELM-FSSHDYTQAIDVWSVGCIF

AELMVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEA-KAFILS-QPHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTAKQVMEHPYF
 |..  | . ||  || || .|.  || |.   ..  |..  .... .  | |    .  ..  |   | |||...|.| |. |.|. . . ||. 
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase LmjF19.1440.AA ERK1 30-318 43 6e-91 308.46 In-house 1-289 (289) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-289/289
Sequence Identity: 43% (127 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQSKETFEDIYLVMDLYDTDLNRIIRSRQKLT
|  .. .| || | ||||. .  ..|||||..|  |      .| |||..|.|  || |.| ..  .| .. | . |.|.| .| .||| ..... |.| 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKT-QHLS

DEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLAR--DDQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIFAEL
 .|. ||. |  ||| |.||| |.||||||||||.|  | | ||||||||  | .      || || ||||| ||.. . |  || ..|.|| | | ||.
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIM-LNSKGYTKSIDIWSVGCILAEM

MVGRALLPGTDYIGQLVMIVNLLGSPSIDDME-FLSSEAKAFILSQPHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTAKQVMEHPYF
.  | . ||  |. ||  |. .||||| ||..  .   |.... | ||.| .... ||  | . | ||| |.| | | .|.|  . . ||| 
LSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase LmjF19.1440.AA S_TKc 30-318 26 9.3e-91 308.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-231/231
Sequence Identity: 26% (81 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQSKETFEDIYLVMDLYDT---DLNRIIRSRQ
|......| || |.|. .. ...|..||||...         ..|.||..|. . .| |...|. ...       ...|.||.. |.   || ..|..|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRG

K------LTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTS-AVDVWS
.      ..  | ...| | ...| |.|| ...||||||.|.|..    . ||||||||          | ...|.||..||||     .|.  ..|.||
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCDWWS

LGLIFAELMVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTAKQVME-----
.| |..|...|. . |      |. |. ...|                                    ..|| |...|.|.. |..|.|| ....     
CGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HPYF
  ||.|
KCHPWF
Kinase LmjF19.1440.AA ERK7 30-318 37 8e-90 304.72 In-house 1-292 (292) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-292/292
Sequence Identity: 37% (112 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSLK-HNNLIRLHHFMRPQSKETFEDIYLVMDLYDTDLNRIIRSRQKL
|.. | .| || | |  |.   ... ||.|.    | .     |  ||. ..  .. | |.|||   .| .      ||||| .  .|||. .||  . |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADND---RDIYLVFEFMETDLHAVIRKGNIL

TDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDDQVMS-----SSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLI
 | | || | | .| . |.||..|.||||||||.|....| . .|||||||             .|| || ||||| ||.| .|| .|| .|| ||.| |
KDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEIL-LGSHRYTKGVDMWSIGCI

FAELMVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQ-PHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTAKQVMEHPYF
 .|.. |... |||  . |.  |..... |.  |.| . |.  . .|.| ....  .. ... .. ..| ||| .|||| | .||||.| ..||| 
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase LmjF19.1440.AA Pkinase 30-318 29 1.8e-84 291.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILR--EMEIMTSLKHNNLIRLHHFMRPQSKETFEDIYLVMDLYDT-----DLNRII
| .....| |. |.|. ..  |.|..||.|.....  .  . .. .|  | .|| .|.| | .||.....        .||.||.. .      || ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

R--SRQKL--TDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCAL----AICDFGLARD-DQVMSSSDLTQYVVTRWYRPPEVLGMGSNQYTS
.  .. ..  ...... .| | .||| |.|| ...||||||.|.|.. .. .     |||||||.  |   ..| .| ...|.||..|||.  |.. |..
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

AVDVWSLGLIFAELMVGRALLPGT----DYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFSMATEEATDLLSKLLVFHPARRLTA
.||.||.|.|..|.. || . ||     . . |..||.. .| |   | . ..|.   | ...   .   .. .   ..||. |.....| . |..|.||
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTA

KQVMEHPYF
.|...||.|
EQILQHPWF
Kinase LmjF19.1440.AA CDK 30-318 30 1.7e-80 257.19 In-house 1-284 (284) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-284/284
Sequence Identity: 30% (96 aa)

YDLVKVVGFGACGTVCSAVANGSG-----ERVAIKRLSRVFG---DLREGKRI--LREMEIMTSLKHNNLIRLH-HFMRPQSKETF-----EDIYLVMDL
|. .. .| |..|.|  |    .|     . ||.|..        . .||  |  .||  ..  | | | ..||  ..  ..  ..       .|.|.. 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

YDTDLNRIIRSRQKLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCA-----LAICDFGLARDDQVM-----SSSDLTQYVVTRWYRPPEV
 |.||  ...          . .| |  |||||.|| ..|||||||.|.|.| .       | | ||||||  ...      .  .|  |||.|||.||.
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

LGMGSNQYT--SAVDVWSLGLIFAELMV---GRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFSMATEEATDLLSKL
| .|| .|.   ..|.||.| ||||..    ...|.||.  | || .| ...|.|. |.   ...                             |||.|.
L-LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LVFHPARRLTAKQVMEHPYF
|.. |..|..|.| ..||||
LCYDPKKRISAEQALQHPYF
Kinase LmjF19.1440.AA MAPK-Unclassified 30-182 44 1.4e-64 220.91 In-house 1-163 (575) Show / Hide 
Range on Protein: 30-182
Range on HMM: 1-163/575
Sequence Identity: 44% (72 aa)

YDLVKVVGFGACGTVCSAVANGS-GERVAIKRLSRVFGDLREGKRILREMEIMTSLKHNNLIRLHHFMRPQSKET--FEDIYLVMDLYDT---DLNRIIR
|.. |..| || | || |. . . .  ||||.. ..| .    ||.|||  |   | | |.|..    .. . .   | |||.|||.. |   ||  ||.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

SRQ-KLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLAR---DDQ
|.| .. ..| |||. |  ||| ||||| . ||||||||||.| ||.. |||||..|   |.|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIEDNQ
Kinase LmjF19.1440.AA MAPK-Unclassified 186-318 32 1.2e-39 138.03 In-house 402-575 (575) Show / Hide 
Range on Protein: 186-318
Range on HMM: 402-575/575
Sequence Identity: 32% (57 aa)

SSDLTQYVVTRWYRPPEVLGMGSNQYTSAVDVWSLGLIFAELMVG-----------RALLPGTD--------------------YIGQLVMIVNLLGSPS
. ..|||||||||| || . . .  |. .|| ||.| ||||.|             | |.||.|                    ...|. ||.  ||.| 
CYHMTQYVVTRWYRAPEIM-LSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPP

IDDMEFL-SSEAKAFILSQPHRPALSFRDLFSMATE----------EATDLLSKLLVFHPARRLTAKQVMEHPYF
  |. |  .. |. .| |    . . | ||.  ..           |. |...|.|.| | .| || |  |||||
EEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase LmjF19.1440.AA Pkinase_Tyr 30-221 30 1.4e-16 56.79 Pfam 1-201 (270) Show / Hide 
Range on Protein: 30-221
Range on HMM: 1-201/270
Sequence Identity: 30% (63 aa)

YDLVKVVGFGACGTVCSAVAN----GSGERVAIKRLSRVFGDLRE--GKRILREMEIMTSL-KHNNLIRLHHFMRPQSKETFEDIYLVMDLYDT-DLNRI
  . |. | || |.|. ....    . .  ||.| | .   . ..   .  .||..||..| .| |..||.    .|..     ||.|| .    ||   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDY

IRS----RQKLTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARD---DQVM-SSSDLTQYVVTRWYRPPEVLGMGSNQYTS
 |.    .|.|| ..|  . .|  .|. ||.| .  ||||   | ||. .    |||||||||   |     ... .  .  .|. .||..  |   .|.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWM-APECINYGK--FTT

AVDVWSLG
. |||| |
KSDVWSFG
Kinase LmjF19.1440.AA TyrKc 30-318 21 4.5e-16 37.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-318
Range on HMM: 1-280/280
Sequence Identity: 21% (71 aa)

YDLVKVVGFGACGTVCSAVANGSGERVAIKRLSRVFGDLREGKRILREMEIMTSL--KHNNLIRLHHFMRPQSKETF---EDIYLVMDLYDT-DLNRIIR
  | |. | || |.|. ....   . ||.| |          . ..||..||..|  .| |..||.   . |.   |   | ...|| . .  ||.  .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLR

SRQK-LTDEHLQYFMIQAFRGLHYLHSAKVMHRDLKPSNLLVNADCALAICDFGLARDD----------QVMSSSD--LTQY-VVTRWYRPPEVLGMGSN
.... |. ..| .|..|. .|  |||| .. ||||   | ||...    |.||||.||           .. ...    . . .  ||. .||..    .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--NYG

QYTSAVDVWS----------LGLIFAEL-----MVGRALLPGTDYIGQLVMIVNLLGSPSIDDMEFLSSEAKAFILSQPHRPALSFRDLFSMATEEATDL
 .|.. ||||          .|    .      |  . ..   .  . .    | .  | .                            |  ...|  ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS---------------------------FVCCPDEMYQI

LSKLLVFHPARRLTAKQVMEHPYF
 ..   . |. | | ...  | .|
MKQCWHEDPEDRPTFSEI--HECF