Gene LmjF30.0370 (L.major)

LmjF30.0370

Species: L.major
Alias: LmajK081, LmjF30.0370
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF30.0370.AA Protein None 410 None Fasta, JSON
LmjF30.0370.kin_dom Protein Kinase Domain None 329 None Fasta, JSON

Protein domain

Protein domains of LmjF30.0370.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF30.0370.AA MAPK 32-360 35 2.4e-120 406.12 In-house 1-328 (328) Show / Hide 
Range on Protein: 32-360
Range on HMM: 1-328/328
Sequence Identity: 35% (130 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEP------VAIKKVMHLFDDAVDAKRVLREVKLLAYL-KHPNILSLKDLFKSP-----DPVDTYSELYVVTDLMES
|. . ..| |||| ||||.|  ||.       |||||... |......||..||.||| .. .|.|| .|.| |.       .. . . ..|.|..|||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DMDAILRSPRIRLAAGHGQYFTLQLLCA--LQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDDT---------------MTQYVFTRWYRP
|. .|..|..  |   | |||. |.|..  |.||||| |.||||||.|.| ...| ||..||||||.|  ...               ||.|| ||||| 
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PELLLV--CKHCNYSADMWAVGCLAAEMFT-GKPLFPGKDYINQINLIVELLGIPDLARDLPPST-SKEAIHYLSSL---PPSKGKKLEEYAPELRRRFD
||..|    .|.. . |||.|||  ||| | .||||||||||.|.|||.|.|| |    ..   . |..| .|..||   |. ..| .|.  |  .    
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF---

ETTFYDSFDTELEEAIAVEGAIIARPRPHPPEEYYAEFVDFIFGLLCYNPAKRRTAKESIAHAWL
                                    . .|... .|  .| || |..| ..|  .
--------------------------------NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF30.0370.AA CMGC 32-360 21 7.1e-109 359.05 In-house 1-513 (513) Show / Hide 
Range on Protein: 32-360
Range on HMM: 1-513/513
Sequence Identity: 21% (119 aa)

YNVQHFVGRGAYGFVCSAVD--------------AVTNEPVAIKKVMHLFDDAVDAK----------RVLREVKLLAYLK-----------------HPN
| .   .|.|.|| |....|                ||| |||||..  | .  .||          | |||.|.| .|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILSLKDLFKSPDPVDT-----------YSELYVVTDLMESDMDAILRSPR--------IRLAAGH------------GQYFT------LQLLCALQ--YI
|..|.| |.....  .           . .|| |...|. |   .... .        . |   |             .||.       |.|..|   |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAH--VLHRDLKPGNLLTDSECNL--------------------KLGDFGLARGIGHDD----------------------TMTQYVFTRWYRPPELLL
||.   ..|||||| |.| ...| |                    |..|||||| ... .                      ..|.|| |||||.||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

VC---------KHCNYSADMWAVGCLAAEMFTG--------KPLFP-----------GKDYINQINLIVELLGIPD--------------LARDLPPSTS
 .         .| ... |||.|||  |||.||        |||||           ||..|.|...|...|| |.                .. |  ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

---------------------KEAIHYLSS---LPPSKGKKLEEYAPELRR---------RFDETTFYDSFDTELEEAIAVEGAIIARPRPHPPEEYY--
                     . | .|..|   .|. ..|....  | ...         .|  .  |.                         |.    
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IYE-------------------------EKFKSH

------------AEFVDFIFGLLCYNPAKRRTAKESIAHAWL
             ...|.. ..|.|.|.|| ||..  .| ..
KFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF30.0370.AA ERK 32-285 43 1.4e-102 347.11 In-house 1-269 (307) Show / Hide 
Range on Protein: 32-285
Range on HMM: 1-269/307
Sequence Identity: 43% (119 aa)

YNVQHFVGRGAYGFVCSAVDAV-----TNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLK-HPNILSLKDLFKSPDPVDTYSELYVVTDLMESDMDAIL
|.   ..|.|||| ||||.|       |...|||||..  ||.....|| ||| ||| ..| |.|| .|.|....  |   | ..|.|..|||.|.. | 
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

RSPRIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIG--HDD-------TMTQYVFTRWYRPPELLLVCKHCNYSA
.|.  .|   | |||. |.||.| ||||| |.||||||.|.|  | | ||  ||||||..   ...        ||.|| |||||.||..|  . .. . 
NSQQ-ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAM

DMWAVGCLAAEMFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPP--SKGKKLEE
|.|..||  |||. .|||||||||..|||.| ...| |    ||   .|..|  |...||    ..| .|.
DIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWEN
Kinase LmjF30.0370.AA p38 32-281 41 2.1e-88 299.99 In-house 1-249 (289) Show / Hide 
Range on Protein: 32-281
Range on HMM: 1-249/289
Sequence Identity: 41% (105 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEP---VAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKS-PDPVDTYSELYVVTDLMESDMDAILRS
|.   .|| |||| ||.|.|. |..    ||||| |  | ....|||  ||..||  ..| |...| | |    . ..  .. |.|| .|..|   |...
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

PRIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDDTMTQYVFTRWYRPPELLLVCKHCNYSADMWAVGCLAAE
 |  |   | |.   |.| .| ||||| . ||||||.|.    .| |.  ||||||    || ||.|| ||||| || .|   | .  .|.| ||| .||
QR--LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAE

MFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPPSKGK
. ||..||||.|.|.|.. |....| || .  .    |.||  |. |.|. . .
LITGRTLFPGDDHIDQLQRIMKVCGTPD-EEFWQKIQSEEARNYIQSYPQMPRR
Kinase LmjF30.0370.AA S_TKc 32-360 23 9e-85 288.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-360
Range on HMM: 1-231/231
Sequence Identity: 23% (81 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVDTYSELYVVTDLMES---DMDAILRSP
| .   .|.||.| |. ...  |.. ||||..          ....||...|   .||||  |.| | .       ..||.|.....    |.  .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

RIR-----LAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDDTMTQYVFTRWYRPPELLLVCKHCNY-SADMWAVG
. .     .   | .... |..|||.|.|| ...|||||| |.| |.  ..|..|||||| .      | .. |.||..||.|    . .. ..|.|..|
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CLAAEMFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPPSKGKKLEEYAPELRRRFDETTFYDSFDTELEEAIAVEGAIIARPR
|. .||..|.|.||      |.... ...|                                                                      
CILYEMLCGYPPFP------QMQMMFKKIG----------------------------------------------------------------------

PHPPEEYYAEFVDFIFGLLCYNPAKRRTAKESIA-------HAWL
         |. ||| ..|...|.|| || |  .       | |.
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF30.0370.AA ERK7 32-289 39 3.3e-80 272.77 In-house 1-260 (292) Show / Hide 
Range on Protein: 32-289
Range on HMM: 1-260/292
Sequence Identity: 39% (106 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLK-HPNILSLKDLFKSPDPVDTYSELYVVTDLMESDMDAILRSPRI
|.... .|.|||| |  |.|  | . ||.||.   | ...|| |  ||. .|  .. ||||..| . ..     |    .|.| . ||.|. |. |  .|
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRD----IYLVFEFMETDLHAVIRKGNI

RLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDD-------TMTQYVFTRWYRPPELLLVCKHCNYSADMWAVGC
 |   | ||   ||| |..|.||..|.|||||| |.| |||| .|. |||||| |.. .        .| || ||||| || ||  ..     ||| .||
-LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGC

LAAEMFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPPSKGKKLEEYAPE
  .|| .|||.|||   .|||..|.|... |  . |.    |. |.  |.... .| |.|..  |.
ILGEMLRGKPMFPGTSTMNQIEKILETIPKPT-QEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ
Kinase LmjF30.0370.AA ERK5 32-289 40 5.2e-80 272.13 In-house 1-263 (295) Show / Hide 
Range on Protein: 32-289
Range on HMM: 1-263/295
Sequence Identity: 40% (106 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVDTYSELYVVTDLMESDMDAILRSPRIR
|..   .| |||| ||||.   . . |||||.   ||    ||| .||.|.|   .| ||. ..|. .   |   . . ||| ||||||.  |. |    
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP-

LAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGH------DDTMTQYVFTRWYRPPELLLVCKHCNYSADMWAVGCLA
..  |  ||  |.|  |.|.||| |.|||||| |||    | ||.||||.|||.           ||.|| ||||| |||..  .      |.|.|||. 
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIF

AEMFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSS-LPPSKGKKLEEYAPE
 || . . .|||| ||.|..||.. ||.|  .  .    .     |. . .|. . | .|.  |.
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHM-IQAVSADHVYNYFQKNFPNRQPKDWEKVYPK
Kinase LmjF30.0370.AA CDK 32-360 27 1.4e-74 237.97 In-house 1-284 (284) Show / Hide 
Range on Protein: 32-360
Range on HMM: 1-284/284
Sequence Identity: 27% (100 aa)

YNVQHFVGRGAYGFVCSAVDAVTN-----EPVAIKKVM--HL----FDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVDTY-----SELYVVTD
|     .|.|.|| |  | |  |.     . ||.||..  .      .. .     .||..||  | |||| .|.| . . .. ..      . || | .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFP-ITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMESDMDAILRSPRIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECN-----LKLGDFGLARGIG-------HDDTMTQYVFTRWYRPP
 |. |   ...           . ...||| .| |.|| ...|||||| |.| ..  .     ||..||||||  |          |.|  | |.|||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELLLVCKHCN--YSADMWAVGCLAAEMFT---GKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPPSKGKKLEEYAPELRRRFDETT
|||| .|| .   . |||.|||  |||||   .||||||.  |.|. .| ...| |.   . |  |.                                 
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTED-NWPGVTKLPDY-----------------------------

FYDSFDTELEEAIAVEGAIIARPRPHPPEEYYAEFVDFIFGLLCYNPAKRRTAKESIAHAWL
                                    |.. ..|||.|.|| .|..   | ..
------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF30.0370.AA nmo 33-254 43 3.2e-74 227.48 In-house 2-223 (292) Show / Hide 
Range on Protein: 33-254
Range on HMM: 2-223/292
Sequence Identity: 43% (98 aa)

NVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVDTYSELYVVTDLMESDMDAILRSPRIRL
.    .| ||.| | |  |      ||.||. . | . | .||| ||.|.|.. || |.||..|. ..|. .| . |.||||.|| ||.  |. ||   |
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPH-KDFFQEIYVVTELMQSDLHKIIVSPQ-HL

AAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDDT--MTQYVFTRWYRPPELLLVCKHCNYSADMWAVGCLAAEMFT
.. | . |  |.|  |.|.|||..||||.|||||| .|.| ||. ||||||   .|.   ||| | | .|| ||.|.  .|     |.|.|||. ||.  
SSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLG

GKPLFPGKDYINQINLIVELLGIP
 . ||  .  |.|...|..||| |
RRILFQAQSPIQQLQMITDLLGTP
Kinase LmjF30.0370.AA ERK1 32-276 45 1.7e-72 247.12 In-house 1-244 (289) Show / Hide 
Range on Protein: 32-276
Range on HMM: 1-244/289
Sequence Identity: 45% (113 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVDTYSELYVVTDLMESDMDAILRSPRIR
|   ...| ||||.||||.| |... |||||.   |.     .| |||.|.|   || ||. ..|. .. | ..   ..|.| .||| |.  .|..   .
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKISP-FEHQTYCQRTLREIKILTRFKHENIINIQDIIRA-DTIEQMRDVYIVQCLMETDLYKLLKT--QH

LAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLAR--GIGHDDT--MTQYVFTRWYRPPELLLVCKHCNYSADMWAVGCLAAE
|.  |  ||  |.|  |.||||| |||||||| |||    | ||. ||||||    .|| |  .| || ||||| ||..|  |    | |.|.|||. ||
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE

MFTGKPLFPGKDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLP
|   .|.|||| |. |.|.|. .|| |  . ||     . |  || |||
MLSNRPIFPGKHYLDQLNHILGVLGSPSQD-DLNCIINEKARNYLQSLP
Kinase LmjF30.0370.AA Pkinase 32-275 24 5.3e-67 233.71 Pfam 1-273 (293) Show / Hide 
Range on Protein: 32-275
Range on HMM: 1-273/293
Sequence Identity: 24% (69 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVMHLFDDAVDAKRVLR--EVKLLAYLKHPNILSLKDLFKSPDPVDTYSELYVVTDLMES-----DMDAI
| .   .|.|..| |. ...  |.. ||.|..    ..    .. .|  |..... |.||||. |.| | .       ...|.|....|      |  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

LR-SPRIRL--AAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNL----KLGDFGLARG--IGHDDTMTQYVFTRWYRPPELLLVCKHCNYS
.. . . ..     . . . .|.|..|.|.||  ..|||||| |.| |.....    |..|||||.   . ..  || .. |.||..||... ...  ..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADMWAVGCLAAEMFTGKPLFPGK----DYINQINLIVELLG-IPDLARDLPPSTS-----------------KEAIHYLSSL
.|||..||. .||..|.|.|||.    . ..|. .|.. .| ...  .. . | |                 .|... ....
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC
Kinase LmjF30.0370.AA MAPK-Unclassified 32-185 43 6.9e-62 211.91 In-house 1-159 (575) Show / Hide 
Range on Protein: 32-185
Range on HMM: 1-159/575
Sequence Identity: 43% (69 aa)

YNVQHFVGRGAYGFVCSAVDAVT-NEPVAIKKVMHLFDDAVDAKRVLREVKLLAYLKHPNILSLKDLFKSPDPVD-TYSELYVVTDLMES---DMDAILR
| .|  .| |||| || |.|  . | .|||||| |.| . .|.||||||. .| || ||||. ..| |   ..    .  .|.|.|.|..   |.  |..
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

SPRIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGI
|.   .   | |||. |.|  | |.||| ..|||||| ||| .  |...  |||..| |
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSI
Kinase LmjF30.0370.AA MAPK-Unclassified 191-255 33 7.9e-22 75.33 In-house 405-500 (575) Show / Hide 
Range on Protein: 191-255
Range on HMM: 405-500/575
Sequence Identity: 33% (32 aa)

MTQYVFTRWYRPPELLLVCKHCNYSADMWAVGCLAAEMFTG-----------KPLFPGKD--------------------YINQINLIVELLGIPD
||||| ||||| ||..|. .      |.|..||. |||              .|||||.|                    .. ||..|.. || |.
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPP
Kinase LmjF30.0370.AA TyrKc 32-359 19 7.2e-12 -30.75 SMART 1-280 (280) Show / Hide 
Range on Protein: 32-359
Range on HMM: 1-280/280
Sequence Identity: 19% (69 aa)

YNVQHFVGRGAYGFVCSAVDAVTNEPVAIKKVM-HLFDDAVDAKRVLREVKLLAYL--KHPNILSLKDLFKSP--DPVDTY---SELYVVTDLMES-DMD
    .  |.||.| |. ..     ..||.|..  .        .  .|| ...  |  .||||. |     ..       .     |..|. .|.  | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLK

AILRSPRIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHD-------DTMTQ-------Y-VFTRWYRPPELLL
  ||..| .|   .  .| .|  |  .|.|| .. ||||   | | ...   | .||||.| |..|       |. ..       . .  ||. .|| . 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-

VCKHCNYSADMWAVGCLAAEMFT-GKPLFPG-----KDYINQINLIVELLGIPDLARDLPPSTSKEAIHYLSSLPPSKGKKLEEYAPELRRRFDETTFYD
  . ..   | |. | .  |.|| |..  ||     .. .  |... .    |  . |. |  |                                    
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS------------------------------------

SFDTELEEAIAVEGAIIARPRPHPPEEYYAEFVDFIFGLLCYNP-AKRRTAKESIAHAW
                     .. |.| |         . | .  .. |   . | . .
-----------------F---VCCPDEMYQ-IM-----KQCWHEDPEDRPTFSEIHECF
Kinase LmjF30.0370.AA Pkinase_Tyr 32-193 26 4.7e-09 31.29 Pfam 1-170 (270) Show / Hide 
Range on Protein: 32-193
Range on HMM: 1-170/270
Sequence Identity: 26% (46 aa)

YNVQHFVGRGAYGFVCSAVDA----VTNEPVAIKKVMHLFDDAVD--AKRVLREVKLLAYL-KHPNILSLKDLFKSPDPVDTYSE--LYVVTDLMES-DM
    .  |.||.| |. ..       |. |||.|.. .   .  .   .  .||.|..  | .||||..|          |      .|.|. .|.  |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT-----DQGEPNQIYIVMEYMPHGDL

DAILRSP---RIRLAAGHGQYFTLQLLCALQYIHSAHVLHRDLKPGNLLTDSECNLKLGDFGLARGIGHDDTM-TQ
.  ||..   . .|   .   . .|  ....| .| .  ||||   | | ...   | .|||||| | .||.  ..
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRK
Kinase LmjF30.0370.AA Pkinase 318-360 25 9e-06 21.52 Pfam 230-293 (293) Show / Hide 
Range on Protein: 318-360
Range on HMM: 230-293/293
Sequence Identity: 25% (16 aa)

IARPRPHPPEEYY---------------------AEFVDFIFGLLCYNPAKRRTAKESIAHAWL
| .|..| ....                       |. ||| ..||..|.|| ||..   | |.
IMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF30.0370.AA nmo 326-360 31 4.7e-05 10.81 In-house 258-292 (292) Show / Hide 
Range on Protein: 326-360
Range on HMM: 258-292/292
Sequence Identity: 31% (11 aa)

PEEYYAEFVDFIFGLLCYNPAKRRTAKESIAHAWL
|..   | |. .  .| ..| ||  .|. .|| .|
PDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase LmjF30.0370.AA ERK7 334-360 37 6.1e-05 12.48 In-house 266-292 (292) Show / Hide 
Range on Protein: 334-360
Range on HMM: 266-292/292
Sequence Identity: 37% (10 aa)

VDFIFGLLCYNPAKRRTAKESIAHAWL
.| .  ||..|| || ||.. ..| . 
IDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase LmjF30.0370.AA ERK1 334-360 40 0.003239 7.92 In-house 263-289 (289) Show / Hide 
Range on Protein: 334-360
Range on HMM: 263-289/289
Sequence Identity: 40% (11 aa)

VDFIFGLLCYNPAKRRTAKESIAHAWL
.|..  .| .|| || |  | .|| .|
LDLLDKMLTFNPHKRITVEEALAHPYL
Kinase LmjF30.0370.AA p38 340-360 38 0.011112 4.66 In-house 269-289 (289) Show / Hide 
Range on Protein: 340-360
Range on HMM: 269-289/289
Sequence Identity: 38% (8 aa)

LLCYNPAKRRTAKESIAHAWL
.|   | || ||.| ..|...
MLELDPDKRITAEEAMQHPYF
Kinase LmjF30.0370.AA ERK 340-360 33 0.017779 5.27 In-house 287-307 (307) Show / Hide 
Range on Protein: 340-360
Range on HMM: 287-307/307
Sequence Identity: 33% (7 aa)

LLCYNPAKRRTAKESIAHAWL
.|  .| || |..| ..|  .
MLVFDPDKRITVEECLEHPYF
Kinase LmjF30.0370.AA MAPK-Unclassified 335-360 38 0.204764 0.24 In-house 550-575 (575) Show / Hide 
Range on Protein: 335-360
Range on HMM: 550-575/575
Sequence Identity: 38% (10 aa)

DFIFGLLCYNPAKRRTAKESIAHAWL
||.  .| .|| || || .   |   
DFVQKMLQFNPWKRITADQALEHPYF