Gene LmjF19.0180 (L.major)

LmjF19.0180

Species: L.major
Alias: LmajK089, LmjF19.0180
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
LmjF19.0180.AA Protein None 407 None Fasta, JSON
LmjF19.0180.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of LmjF19.0180.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF19.0180.AA RCK 4-289 50 3.4e-180 576.75 In-house 1-298 (298) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-298/298
Sequence Identity: 50% (154 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECLQLREIQSLRKVQ-HPNLVKLKEVVREKT--ELFMIFEYCEKNIFQIQRQ---RADEM
|... |||||..|.| ||||. |||||| |||||.|.||||| .||||.||||.  |||..|||||.|...  .|. .|||...|..|  .    |   .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

SGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISG----------DLVKVADFGLAKEIRSRPPFTEYVSTRWYRAPELVLHSTHYNSPVD
. ..      |..|| |.|.|   .|| ||.||||||||....|          |..|.|||||..||||.||.|.|||||||||||. |..|.||||.|
PENQR----SIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMD

IWACAVIFAELYLCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTATQCLQHP
|||   |..|||  ||||||.|| ||.||||.|.|.| . .|..||.||. || .|| . ..|| .... ... ...||  ||. .| .|.|| |.||||
IWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHP

YF
||
YF
Kinase LmjF19.0180.AA MAK 4-289 43 2.5e-161 517.66 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-352/352
Sequence Identity: 43% (155 aa)

YTVMGQLGDGSFGTVSKAQN------------------------------TSTGEIVAVKKMKQRFHSWEECLQLREIQSLRKVQ-HPNLVKLKEVVR--
|... |||||..|.| .|.                               . |||.||.|.||. |.|||||..|||. ||.| . |||.||||||.|  
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

EKTELFMIFEYCEKNIFQIQRQRADEMSGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISG------------------DLVKVADFGLA
|  .|...||| . | .|.   |      .  |.  .||.|| | | | . .|| || |||.||||....|                  .|.|.||||||
ENDHLYFVFEYMKENLYQMMKDRD-----RRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLA

KEIRSRPPFTEYVSTRWYRAPELVLHSTHYNSPVDIWACAVIFAELYLCRPLFPGTSESDQLFKICSVLGSPAPNE----------------WDEGYQLA
 ||||.||.| |||||||||||  |.|| |.||.|.||   | ||||  ||||||.|| ||.||||.|||.|   .                |..|||||
REIRSKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLA

RRMNMRFPTVAP---TPLRHILTTAPP-AAVDLMAQMLRFNPAERPTATQCLQHPYF
  ||.||| . |   .|| |.. .. .  |..||  ||...| .|||| ||...|||
HMMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase LmjF19.0180.AA CMGC 4-289 23 8.3e-122 402.33 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YTVMGQLGDGSFGTVSKAQN--------------TSTGEIVAVKKMKQRFHSWEECL-----------QLREIQSLRKVQ-----------------HPN
|......| |..|.| |...              . |.||||.||.|..|   |...            ||||. |....                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVKLKEVVREKT-----------------ELFMIFEYCEKNIFQIQRQRADEMSG--TVAFSDKE------------IRSIM------CQTLLGVQ--AI
.|||..... |                  .|...|||.... .|. ..  . . |   . .|. .            |...|       | | |.    .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HKAG--FMHRDLKPENLLISGD---------------------LVKVADFGLAK--EIRSRP--------------------PFTEYVSTRWYRAPELVL
|...  ..||||||||.||. .                      .|..|||||.  ...|..                    |.|.||.||||||||. |
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

HS---------THYNSPVDIWACAVIFAELYLC--------RPLFPGTSE-----------SDQLFKICSVLGSPA---------------PN-------
 .         .||..|.|.|... ||||.|.         .||||| ||            ||||||. |||.|                ..       
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------EWDEGYQLARRMNMRFPTVAPTPLRHILTT-----------------------------------APPAAVDLMAQMLRFNP
                  .|.|........| |||.. | |.. .                                      ..| |.||. .||...|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

AERPTATQCLQHPYF
..|.|| |.||||||
DKRITAEQALQHPYF
Kinase LmjF19.0180.AA CDK 4-289 33 7.89999999999e-105 336.34 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-284/284
Sequence Identity: 33% (108 aa)

YTVMGQLGDGSFGTVSKAQNTSTG-----EIVAVKKMK---QRFHSWE-ECLQ---LREIQSLRKVQHPNLVKLKEVVREK-----------TELFMIFE
|    ..| |..|.| ||... ||     .||| || .   .   . | | .    .|||  |..  ||| |||..|.  |           . |.|.||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YCEKNIFQIQRQRADEMSGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGDL------VKVADFGLAKEIRS-------RPPFTEYVST
|..    .. .                |...| | | |.  .|. ..||||||| |.||. .       .|.||||||..  .       . ..|  | |
YMDHDLKKYMD----------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT

RWYRAPELVLHSTHYN--SPVDIWACAVIFAELYL---CRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAA
.||||||| | |.||.   |.|.|..  ||||...    .|||||.|| ||||||. ..|.| .. | .  .|                           
LWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------

VDLMAQMLRFNPAERPTATQCLQHPYF
 ||. .|| ..|. | .|.|.||||||
-DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF19.0180.AA CDK7 4-289 37 7e-100 266.67 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-288/288
Sequence Identity: 37% (109 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMK-----QRFHSWEECLQLREIQSLRKVQHPNLVKLKEVVREKTELFMIFEYCEKNIFQIQRQRADEMS
|. . ..| | |.||.||. ..||.|||.|| |       .    .   .|||  |.  ||.| . |  .   |. . ..|.. .     . .       
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKS----

GTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGD-LVKVADFGLAKEIRS-RPPFTEYVSTRWYRAPELVLHSTHYNSPVDIWACAVIFA
  . .   .| ..| .||.|. . |.    |||||| |||.. .  .|.||||||. . |    .|  | |||||||||     || . ||.|.  .|||
--IILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFA

ELYLCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMR-FPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTATQCLQHPYF
|| |  | .||.|. ||| .|.. || | . || .  ...  . .. ||  . |||||| | |.  ..|||. |. .|| .| |.||||..|||
ELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase LmjF19.0180.AA Pkinase 4-289 33 8.6e-98 335.98 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-293/293
Sequence Identity: 33% (102 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECLQLR---EIQSLRKVQHPNLVKLKEVVREKTELFMIFEYCEK-----NIF----QIQR
|.. ...| ||||.| |... .||.|||||..| |  ..... ..|   ||| .....||| |.|......|... |..||||.       |        
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

QRADEMSGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLIS--GDL---VKVADFGLAKE--IRSRPPFTEYVSTRWYRAPELVLHSTHYNS
    ...|.. ||..|....| |.| |.. .|. |..||||||||.||.  |..   ||..||||||   . . . .| .. |.||.|||.......| .
----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

PVDIWACAVIFAELYLCRPLFPGT----SESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTA
.||.|.| .|..|... ||.|||     .  ||...|| ..| | . .|.. .   ...  |. . . . ..   . ..... |..  .|...|..||||
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTA

TQCLQHPYF
.|.||||.|
EQILQHPWF
Kinase LmjF19.0180.AA S_TKc 4-289 29 1.7e-92 314.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-231/231
Sequence Identity: 29% (87 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECLQLREIQSLRKVQHPNLVKLKEVVREKTELFMIFEYCEK---NIFQIQRQRADEMSGT
|... ..| |.||.| |.....||.|||.|..|        .  .|||| |.| .|||.|||..| .. ..|.|..|||.    . |.. ..|  .  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR-

VAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGDLVKVADFGLAKEIRSRPPFTEYVSTRWYRAPELVLHSTHYNS-PVDIWACAVIFAELY
. |.  ..|..|.|...... .|. |..||||||||.|..   .|..|||||...      | .. |.||.|||..    .|.  ..|.|.| .|..|..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

LCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTATQCLQ-------HPYF
  .|.||   . ...||..                                        .| | |.. ..|...|..|||| ..||       ||.|
CGYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF19.0180.AA CDC2 4-289 36 5.3e-84 257.97 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-301/301
Sequence Identity: 36% (113 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEEC-----LQLREIQSLRKVQ-HPNLVKLKEVVREKTELFMIFEYCEKNIFQIQRQRADEM
|.    .| |..| | |.... |..|||.||   |  . .|        .|||  | . . |||.|||..|. .   |.|.|||.. .  . ...    .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI--RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN

SGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGD-LVKVADFGLAKEIR--SRPPFTE-YVSTRWYRAPELVLHSTHYNSPVDIWACAV
     ..   ..|.| | | ||   |  . ||||||| |.||. .  .|.||||||. .   .|.  ||  | |.||||||. | . .|. |||.|.   
---KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

IFAELYLC---RPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTT---------APPAAVDLMAQMLRFNPAERPTAT
||||...    .|||.| || ||||||  .||.|  ..| . .||    .. ||   |. |..|.           ..| ..||  |||. .|. | .| 
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQL-PDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAK

QCLQHPYF
. ||||||
EALQHPYF
Kinase LmjF19.0180.AA MAPK 4-289 31 5.9e-83 281.9 In-house 1-328 (328) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-328/328
Sequence Identity: 31% (106 aa)

YTVMGQLGDGSFGTVSKAQNTS------TGEIVAVKKMKQRFHSWEECLQ-LREIQSLRKV-QHPNLVKLKEVVREK-----------TELFMIFEYCEK
|.   ..| |..|.| .|  ..      .|..||.||. . |..   |   .|||  ||   .|.| .||... . .            .. ...|..| 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NIFQIQRQRADEMSGTVAFSDKEIRSIMCQTLLG--VQAIHKAGFMHRDLKPENLLISGD-LVKVADFGLAKEIRSR-------PPF--------TEYVS
.  || ...          ||. |...| | | |  .. || |.  ||||||.|.|.  . ..|..|||||  | .        . .        ||||.
DLHQIIKSQQ-------PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVA

TRWYRAPELVLH--STHYNSPVDIWACAVIFAELYL-CRPLFPGTSESDQLFKICSVLGSPAPNEW-DEG-YQLARRMNMRF---PTVAPTPLRHILTT-
||||||||. |   ..||.  ||.|..  ||||..   .|||||..  ||...| .|||.| .  .   . .. || .  ..   |   . |.....   
TRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNA

---APPAAVDLMAQMLRFNPAERPTATQCLQHPYF
   | | |.||. .|| |.| .| |. ..||||||
NFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF19.0180.AA MOK 4-289 38 2.2e-80 251.57 In-house 1-283 (283) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECLQLREIQSLRKVQ-HPNLVKLKEVV--REKTELFMIFEYCEKNIFQIQRQRADEMSGT
|  .|..|.|.|  | | |    |.  | |.|||.| | |.  .||||| .|... |||...|.|||  |   .| .| |  . ||. . | |   .   
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYL---

VAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGDLVKVADFGLAKEIRSRPPFTEYVSTRWYRAPELVLHSTHYNSPVDIWACAVIFAELYL
   ..| |.  | | .  .. .|. |  ||| ||||.||  | .|.||||  . . |. |.|||.||||||||| .|   .|   .|.|.   .| |.  
---PQKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIAS

CRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTATQCLQHPYF
 .|||||  | ||. ||  |.| |.        . .| ||  ||      .  ... . . ....| .|  . | || || | .|||||
LHPLFPGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase LmjF19.0180.AA CDKL 4-289 37 1.5e-79 270.58 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-286/286
Sequence Identity: 37% (109 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQ-RFHSWEECLQLREIQSLRKVQHPNLVKLKEVVREKTELFMIFEYCEKNIFQIQRQRADEMSGTVA
|  .| .| || |.| |  |  ||.|||.|| |  .    .    .|||  |.   |.|.| |.|| | | .|.. ||||....  .  .     .|   
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEE---YPNG---

FSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLIS--GDLVKVADFGLAKEIRSRPP--FTEYVSTRWYRAPELVLHSTHYNSPVDIWACAVIFAEL
  .. .|..| |.| ...  ||    ||| ||||.||.   . ||  |||.|. . . |    |.|| |||||||||..  | | .|||||| . ..||.
VDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEM

YLCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTV-APTPLRHILTTAP-PAAVDLMAQMLRFNPAERPTATQCLQHPYF
    ||.|| |. |||..|  .||   |      ..  .   |.|| .  . ||.  . ..  ..| |.| ..|  .|.||.|..|...||||
IDGQPLWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase LmjF19.0180.AA CDK4 4-289 37 2.1e-66 226.77 In-house 1-290 (290) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-290/290
Sequence Identity: 37% (114 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEE-----CLQLREI---QSLRKVQHPNLVKLKEV------VREKTELFMIFEYCEKNIFQI
|  .  .| | .||| .|  . || .|| |.   |  . ||        .|||     | .  ||| |||..|      .| .. . |.|| |.    . 
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQV--RIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTY

QRQRADEMSGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLI-SGDLVKVADFGLAKEIRSRPPFTEYVSTRWYRAPELVLHSTHYNSPVDI
 ..     .|    . . |. .| | | ||   |     ||||||.|.|. |   || ||||||..  .   .|  | | ||||||  | |. ||.|||.
LDKCP--PPG---MPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPVVVTLWYRAPEVLLQSY-YNTPVDM

WACAVIFAELYLCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQMLRFNPAERPTATQCLQHPY
|. . ||||.|  ||||.|.|| ||| ||  | | |   .|     |..     ||   |.|.. . .     . ||. .||..|.. |..| |||||||
WSVGCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWDH---FPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPY

F
|
F
Kinase LmjF19.0180.AA TyrKc 4-289 20 2.6e-15 25.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECLQLREIQSLRKV--QHPNLVKLKEVVREK-------TELFMIFEYCEKNIFQIQRQRA
 |   .|| | ||.| |.. .   . ||||..|       .   .||.. ..|.  .|||.|.|  |....         |....||...   .   .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DEMSGTVAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGDL-VKVADFGLAKEIRSR-------PPFT------EY--VSTRWYRAPELVLH
 .      .. |.  |.. |   | . .|. .. ||||   | |.. .. ||..||||...| .           .      .   .  ||. ||| .. 
RPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APE-CIN

STHYNSPVDIWACAVIFAELY-LCRPLFPG-----TSESDQLFKICSVLGSPAPNE----WDEGYQLARRMNMRFPTVAPTPLRHILTTAPPAAVDLMAQ
   ...  |.|.  |   |.. .. .  ||      | .. . .. .    | | .                                ..|..  ..| |
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------F-VCCPDEMYQIMKQ

MLRFNPAERPTATQCLQHPYF
  ...|..||| ...  | .|
CWHEDPEDRPTFSEI--HECF
Kinase LmjF19.0180.AA Pkinase_Tyr 4-84 26 4.6e-12 41.47 Pfam 1-91 (270) Show / Hide 
Range on Protein: 4-84
Range on HMM: 1-91/270
Sequence Identity: 26% (24 aa)

YTVMGQLGDGSFGTVSKAQNT----STGEIVAVKKMKQRFHSWE--ECLQLREIQSLRKV-QHPNLVKLKEVVR-EKTE--LFMIFEYCEK
 | . .|| |.||.| |.  .    .|.  ||||..|.  .. .      .||.. ...  .|||.|.|  |.  ..    .....||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase LmjF19.0180.AA Pkinase_Tyr 136-190 27 0.002743 11.76 Pfam 141-199 (270) Show / Hide 
Range on Protein: 136-190
Range on HMM: 141-199/270
Sequence Identity: 27% (17 aa)

NLLIS-GDLVKVADFGLAKEI----RS-RPPFTEYVSTRWYRAPELVLHSTHYNSPVDIWA
| |.. .  ||..|||||. |       |      .  .|. |||   ..  ...  |.|.
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKSDVWS