Gene LmjF07.0170 (L.major)

LmjF07.0170

Species: L.major
Alias: LmajK108, LmjF07.0170
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF07.0170.AA Protein None 1064 None Fasta, JSON
LmjF07.0170.kin_dom Protein Kinase Domain None 388 None Fasta, JSON

Protein domain

Protein domains of LmjF07.0170.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF07.0170.AA S_TKc 28-415 18 8.4e-68 232.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-415
Range on HMM: 1-231/231
Sequence Identity: 18% (72 aa)

YKIVEKMATGSFGVIFKVRRVTDHQVFVMKRIPLLGLTAPQRRDAAQEIILMRDLHHPCVVSQRDAFLYNEHDLCLVMDYYDG--GDMDTHMAAQRD--L
|.|..|   |.||. .|.| . ..... .|.|.         ... .|| ...  ||| .|   |.|    ..|..||.| ||  ||. ...  ..   |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

DMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDFGISERLGVDLANHTWVAGATMSGPHGSDGSSLTSVPAMVTATAAGSPS
. .|   ..  .. |.... .|.| |...|||.|  |... .    . ..|||.. .|                                          
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------------------------------------------

PARVNRVDDAMRSLSISGGLRPSTPGGAGAGAPVLSPLLHQQMAWSSGQWGAESHICSPNSSPYQPLSHMRQTSASSNAASSCSLQRLLNGGVEAAMKGT
                                                                                                . ||
----------------------------------------------------------------------------------------------TTFCGT

PLYMAPEVLQGGAASP-KSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRGQREPLPTHYPRPIADLISSMLCLDASQRPSCEEVLT-------VPCV
| |||||||     .. |.|.||.||.|||.|. . ||.  ... .  ...           ...  |.|. .|. | ..||.. |.|.        | .
PWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF07.0170.AA CAMK 33-415 13 3.8e-50 159.37 In-house 1-425 (425) Show / Hide 
Range on Protein: 33-415
Range on HMM: 1-425/425
Sequence Identity: 13% (73 aa)

KMATGSFGVIFKVRRV-TD-----------HQVFVMKRIPLLGLT--------------------------APQRRDAAQEIILMRD-------LHHPCV
.  .||||. .....  |            .| . .| |.   |.                          .  |.   .|| .|.        |.||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSQRDAFLYNEH------------------DLCLVM---DYYDGG----DMDTHMAAQRDL-----------DMYFELDQVMLWFVQLVLGAQYLHAHNV
..  ...  ...                  ....||   .| .||    |.  .  ....            . .|. ...  .| |.. . .|.| ||.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKTHNVFVRSKD----------------MSVVLGDFGISERLG-------------------VDLANHTWVAGATMSGPHGSDGSSLTSVPAMVTA
||||.|  |. . ...                  . . ||| . ..                    .                                 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW---------------------------------

TAAGSPSPARVNRVDDAMRSLSISGGLRPSTPGGAGAGAPVLSPLLHQQMAWSSGQWGAESHICSPNSSPYQPLSHMRQTSASSNAASSCSLQRLLNGGV
                                                                                                    
----------------------------------------------------------------------------------------------------

EAA--------MKGTPLYMA-PEVLQG--------------GAASPKSDVWSLGCVLYELLALRHPFESR-------------DLAPLVMRVLRGQREPL
           . ||| ||| ||||.|                 .||.|.||.|..|| .|  . ||..              ..  |  ....|. .  
TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFP

PTHYPR-----------------------PIADLISSMLCLDASQRPSCEEVLTVPCV
| . .                           |||..||. | ..|...|..|  | .
PPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF07.0170.AA NEK 28-178 32 7e-48 165.38 In-house 1-170 (286) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-170/286
Sequence Identity: 32% (56 aa)

YKIVEKMATGSFGVIFKVRRVTDHQV-----FVMKRIPLLGLTAPQRRDAA-QEIILMRDLHHPCVVSQRDAFLYNE-HDLCLVMDYYD-GGDMDTH---
|.|..|   ||||. .||||  | ..     .|.|.| . ...  ....|  .|... . |.|| .|. .|.|. .. . || ||.| . |||.. .   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

MAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAH-----NVVHRDIKTHNVFVRSKDMS---VVLGDFGIS
   |..   ||| .|.. ||.|..|. .|.| .     ...|||||. |.|  .....   | .||||||
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS
Kinase LmjF07.0170.AA STE 28-415 15 1.2e-43 151.29 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-415
Range on HMM: 1-359/359
Sequence Identity: 15% (76 aa)

YKIVEKMATGSFGVIFKVRRVT---------------DHQVFVMKRIPLLGLTA---------------PQRRDAAQEIILMRDLH--HPCVVSQRDAFL
....||   |.||. .| ...                 .... .|...|   ..                .. .  .|| .|....  || .|   ....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YN------EHDLCLVMDYYDGGDMD---THM-AAQRDLD------MYFELDQVMLWFVQLVLG-AQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDFGIS
..      ...|...| | |||  |    |    ...|.       .|. .|.    .|.. |  .||| |...|||||  |...      | | |||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

ERLGVDLA-------NHTWVAGATMSGPHGSDGSSLTSVPAMVTATAAGSPSPARVNRVDDAMRSLSISGGLRPSTPGGAGAGAPVLSPLLHQQMAWSSG
 .|  ..|       .                                                                                    
GQLTDSMANIQSNNII------------------------------------------------------------------------------------

QWGAESHICSPNSSPYQPLSHMRQTSASSNAASSCSLQRLLNGGVEAAMKGTPLYMAPEVLQG------GAASPKSDVWSLGCVLYELLALRHPFES-RD
                             .    |.   . ...    . ||| .|||||.|.      .  . |.|.|||||.. |..  ..|.    .
-----------------------------D----CI---ETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHP

L-----AP----------LVMRVLRGQREPLPT-------------------HYPRPIADLISSMLCLDASQRPSCEEVLT--VPCV
.     .|          ..  .. |.  |||.                   ..  .  | |.  |  | ..||. .. |    | .
MRAMFMIPFNYHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF07.0170.AA CAMKL 28-415 16 8.4e-42 131.08 In-house 1-297 (297) Show / Hide 
Range on Protein: 28-415
Range on HMM: 1-297/297
Sequence Identity: 16% (72 aa)

YKIVEKMATGSFGVIFKVRR-VTDHQVFVMKRIPLLGLT-APQRRDA------------AQEIILMRDLH---HPCVVSQRDAFLYNEH-----DLCLVM
|.|..   .||||.    .   |  .   .| |   ...  |. ..              .|| .|. |.   || ...  . .   ||     ...|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYYDGGD--MDTHMAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMS-VVLGDFGISERLG-VDLANHTWVAGATMSGPHG
 | .||.  .  .  ....    .. ..    | |.| . .|.| |..||||||  |. . ..... . . ||| |     .                  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC------------------

SDGSSLTSVPAMVTATAAGSPSPARVNRVDDAMRSLSISGGLRPSTPGGAGAGAPVLSPLLHQQMAWSSGQWGAESHICSPNSSPYQPLSHMRQTSASSN
                                                                                                    
----------------------------------------------------------------------------------------------------

AASSCSLQRLLNGGVEAAMK------GTPLYMAPEVLQG---GAASPKSDVWSLGCVLYELLALRHPFESR--------DLAPLVMRVLRGQREP-LPTH
              .    .      |.| |||||..||       || |.||.| .|| ..  . ||.          .   |  .. .|  .|  . |
--------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYH

YPRPIADLISSMLCLDASQRPSCEEVLTVPCV
 . .  |||..||  . ..||......  | .
VS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase LmjF07.0170.AA NEK 322-415 46 5.1e-40 138.74 In-house 186-286 (286) Show / Hide 
Range on Protein: 322-415
Range on HMM: 186-286/286
Sequence Identity: 46% (47 aa)

GTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLAL--RHPFESR--DLAPLVMRVLRG-QREPLPTH--YPRPIADLISSMLCLDASQRPSCEEVLTVPC
||| ||.|||.|.   . |||.|||||||||. .|  .||||.   ..  |.|.. .| | .|.| |  | .   .|||.||. | .|||||...|  |.
GTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPF

V
.
I
Kinase LmjF07.0170.AA NEK1 28-178 30 3.3e-34 116.14 In-house 1-168 (276) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-168/276
Sequence Identity: 30% (51 aa)

YKIVEKMATGSFGVIFKVRRVTDHQVFVMKRIPLLGLTAPQRRDAAQEIILMRDLHHPCVVSQRDAFLYNEH-DLCLVMDYYDGGDMDTHMAAQRDLDMY
| .  .   ||||  ..|..  | |..|.| | .       | ..  | .. . . || .|. ...|  | .  |  ||.| ||||.     .|.     
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVR--SKDM--------------SVVLGDFGIS
|  || | ||.|..|. .. |  .. |||||. |.|    ...|               | ||||||.
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIA
Kinase LmjF07.0170.AA NEK4 28-178 32 1.4e-32 114.39 In-house 1-149 (257) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-149/257
Sequence Identity: 32% (50 aa)

YKIVEKMATGSFGVIFKVRRVTDHQVFVMKRIPLLGLTAPQRRDAAQEIILMRDLHHPCVVSQRDAFLYNEH-DLCLVMDYYDGGDMDTHMAAQRDLDMY
| ..     ||.| .. ||   |   .|||.. |.     .|..| .|. |.  | || .|.  . .   .   |. || . .|||. . .  |.     
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQK--NQF

FELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDFGIS
 |  ||. ||||  .. ||.|  ...||| || |.|   | . . .||||||
LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNI-IKIGDFGIS
Kinase LmjF07.0170.AA NEK1 322-415 42 5.3e-32 108.37 In-house 183-276 (276) Show / Hide 
Range on Protein: 322-415
Range on HMM: 183-276/276
Sequence Identity: 42% (40 aa)

GTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRGQREPLPTHYPRPIADLISSMLCLDASQRPSCEEVLTVPCV
||| |  ||  |      |||.||||||||||..| ||||.. .  ||.....|   |.| || . .  |.|.|.  ... |||   .|. | .
GTPYYLSPEICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase LmjF07.0170.AA NEK8 37-182 28 1.5e-31 87.21 In-house 10-171 (278) Show / Hide 
Range on Protein: 37-182
Range on HMM: 10-171/278
Sequence Identity: 28% (47 aa)

GSFGVIFKVRRVTDH--QVFVMKRIPLLGLTAPQRRDAAQEIILMRDLHHPCVVSQRDAFLYNEHDLCLVMDYYDGGDMDTHMAAQRD---LDM------
|.||.    ||  |   .  . | |.. ... ..|..|  || .   |.|| ..|  | |.  .  |  .| | |||      . |..   ...      
GAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFM-EDNTLMIEMEYADGGTLYQMIQHQQNKLFEEERQLKQV

------YFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKD-MSVVLGDFGISERLG
      || . ..   |.| ...  ..| ||..|||.|| |.|   .. | | .||||||  ..
NHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFM-TRHRMVVKIGDFGISKIMN
Kinase LmjF07.0170.AA Pkinase 28-193 23 1.7e-31 112.47 Pfam 1-173 (293) Show / Hide 
Range on Protein: 28-193
Range on HMM: 1-173/293
Sequence Identity: 23% (42 aa)

YKIVEKMATGSFGVIFKVRRVTDHQVFVMKRIPLLGLTAPQRRDAAQ--EIILMRDLHHPCVVSQRDAFLYNEHDLCLVMDYYDGG----DMDTHMAAQR
|.|..|   ||||. .| ... . .....|.|.. .    ... ..   || .|. |.||..|  .|.| . . ....||.| .||    |  ... ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

DLDMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSV----VLGDFGISERL-GVDLANHTWVAG
.  .||. ...  .. |.. | .|.|.....|||.|  |...  ... .     ..|||... .        |...|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCG
Kinase LmjF07.0170.AA NEK8 322-415 38 1.3e-30 84.52 In-house 184-278 (278) Show / Hide 
Range on Protein: 322-415
Range on HMM: 184-278/278
Sequence Identity: 38% (37 aa)

GTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRG-QREPLPTHYPRPIADLISSMLCLDASQRPSCEEVLTVPCV
|||.|| ||  .|     |||.|.|||||||.. |.  ||   |  ||.   ..   ||.. ||      |... | .|. ||||  ...  | .
GTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase LmjF07.0170.AA NEK4 310-415 35 8.5e-27 93.35 In-house 150-257 (257) Show / Hide 
Range on Protein: 310-415
Range on HMM: 150-257/257
Sequence Identity: 35% (38 aa)

RLLN--GGVEAAMKGTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRGQREPLPTHYPRPIADLISSMLCLDASQRPSCE
| ||  . .   | ||| || ||.    .   |||.||||| .||.  |.| |. .|.  |. ... ||  |.|  |   ...|.  ||     .|||  
RVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIF

EVLTVPCV
...  | .
DIFQMPYI
Kinase LmjF07.0170.AA Pkinase 322-415 28 5.2e-24 85.97 Pfam 173-293 (293) Show / Hide 
Range on Protein: 322-415
Range on HMM: 173-293/293
Sequence Identity: 28% (35 aa)

GTPLYMAPEVLQ-GGAASPKSDVWSLGCVLYELLALRHPFESR-------DLAPLVMRVLRGQREPLPTHYP-------------------RPIADLISS
||| ||||||.. |   .||.|.||.||.|||.|  | || ..       ... ....  .  ... |. ..                   ..  |.|..
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

MLCLDASQRPSCEEVLTVPCV
.||.| ..||..|..|  | .
CLCKDPKKRPTAEQILQHPWF
Kinase LmjF07.0170.AA TKL 322-413 26 3e-23 80.55 In-house 235-364 (364) Show / Hide 
Range on Protein: 322-413
Range on HMM: 235-364/364
Sequence Identity: 26% (34 aa)

GTPLYMAPEVLQGG----------------AASPKSDVWSLGCVLYELLALRHPFESRDL----------APLVMRVLRGQREPLP------------TH
||| .||||||.|                  .|.|.||.| | ||.|.|. ..|..  .           . ..|....|.| |.|            ..
GTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPD

YPRPIADLISSMLCLDASQRPSCEEVLTVP
 |.....|.      |...|||..|.|   
CPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF07.0170.AA NEK-Unclassified 76-178 36 1.4e-22 71.32 In-house 44-144 (258) Show / Hide 
Range on Protein: 76-178
Range on HMM: 44-144/258
Sequence Identity: 36% (38 aa)

IILMRDLHHPCVVSQRDAFLYNEHDLCLVMDYYDGGDMDTHMAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDF
||..  | || .|   |.|  |   |    || |||..|  .  .|     |.   .| |..|..   || |   ..||| |. |.|   .|  | .|||
IIILSQLRHPHIVTYHDSFFENAK-LFYTQDYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFL-TDDDTVSMGDF

GIS
|||
GIS
Kinase LmjF07.0170.AA NEK11 310-415 37 2.7e-21 74.33 In-house 152-259 (259) Show / Hide 
Range on Protein: 310-415
Range on HMM: 152-259/259
Sequence Identity: 37% (40 aa)

RLLNGGVEAA--MKGTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRGQREPLPTHYPRPIADLISSMLCLDASQRPSCE
||| |  . |  . ||| ||.|| |.      |||.||| |.|||.  . | |   .   .|...  |.   ||  ||| .  .. .||  . | |||  
RLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAI

EVLTVPCV
..| .| .
DILKIPYM
Kinase LmjF07.0170.AA NEK-Unclassified 322-415 30 2.4e-20 63.8 In-house 159-258 (258) Show / Hide 
Range on Protein: 322-415
Range on HMM: 159-258/258
Sequence Identity: 30% (30 aa)

GTPLYMAPEVLQGGAASPKSDVWSLGCVLYELLALRHPFESRDLAPLVMRVLRGQR------EPLPTHYPRPIADLISSMLCLDASQRPSCEEVLTVPCV
||. .|.|||.|      .||||||||..||. .    |  . .  . | . ..        ||    |     ..|  ||  .  ||||  |..  . .
GTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase LmjF07.0170.AA TKL 34-178 16 9.9e-20 67.73 In-house 1-201 (364) Show / Hide 
Range on Protein: 34-178
Range on HMM: 1-201/364
Sequence Identity: 16% (36 aa)

MATGSFGVIFKVRRVTDH--------QVFVMKRIPLLGLTAPQR-------------------------RDAAQEIILMRDLHHPCVVSQRDAFLYNEHD
   |.||...| .             .. ..|...        .                             .|| .|. |.|| .|.   . ......
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LCLVMDYYDGGD-MDTHMAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAHN--------VVHRDIKTHNVFVRSKDM-----------
            ||.||.|..||.  ...            ..| . |  .  .| .|||..|        ..|||.|..|..| ..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

--SVVLGDFGIS
   . ..|||.|
DWCCKICDFGLS
Kinase LmjF07.0170.AA NEK11 28-178 30 2.3e-19 67.17 In-house 1-151 (259) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-151/259
Sequence Identity: 30% (47 aa)

YKIVEKMATGSFGVIFKV---RRVTDHQVFVMKRIPLLGLTAPQRRDAAQEIILMRDLHHPCVVSQRDAFLYNEHDLCLVMDYYDGGDMDTHMAAQRDLD
| .  |.  |||| .. |   .      . |.| |    |       |  |  |.  |||| .|    .|.  .   |.. .| .| |.| ..   ..  
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQD-NFCIITEYCEGRDLDYRIQEYKQAG

MYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDFGIS
  |   |.. ||.||.||  |.|   ..|||.|  |.|.  |   . .||||.|
KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFL--KNNLLKIGDFGVS
Kinase LmjF07.0170.AA TyrKc 28-415 15 1.8e-11 -37.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-415
Range on HMM: 1-280/280
Sequence Identity: 15% (66 aa)

YKIVEKMATGSFGVIFKVRRVTDHQVFV--MKRIPLLGLTAPQRRDAAQEIILMRDL--HHPCVVSQRDAFLYNE-------HDLCLVMDYYDGGDMDTH
 .  .|   | ||...| .     || |  .|           |.|  .|. .|. |  |||..|    .    .       . |..|| | ..|| . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

MAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSVVLGDFGISERLGVDLANHTWVAGATMSGPHGSDGSSLTSVPAMVTA
  . |.    . ...   . .|   | .||| .|..|||. . |. | ..                                                  
LRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------------------------------

TAAGSPSPARVNRVDDAMRSLSISGGLRPSTPGGAGAGAPVLSPLLHQQMAWSSGQWGAESHICSPNSSPYQPLSHMRQTSASSNAASSC-----SLQRL
                                                                                         .      | | 
----------------------------------------------------------------------------------------TVKISDFGLSRD

LNGG-------VEAAMK---GTP--L---YMAPEVLQGGAASPKSDVWSLGCVLYELLAL-RHPFES-----RDLAPLVMRVLRGQREPLPTH-------
.  .           .|   |.   |    ||||... |  ..|||||| | ...|.. .   | .       . . .. .| .| | | | .       
IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFV

-YPRPIADLISSMLCLDASQRPSCEEVLTVPCV
  |  . .....    |...||. .|.  . | 
CCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF07.0170.AA Pkinase_Tyr 74-178 25 3.5e-07 24.93 Pfam 52-158 (270) Show / Hide 
Range on Protein: 74-178
Range on HMM: 52-158/270
Sequence Identity: 25% (28 aa)

QEIILMRDL-HHPCVVSQRDAFL-YNEH-DLCLVMDYYDGGDMDTHMAAQRDLDMYFELDQVMLWFVQLVLGAQYLHAHNVVHRDIKTHNVFVRSKDMSV
.|. .|. | ||| .|.   . .   |.  ...|| |  .||....  ..|. .  . . .   . .|   | .||...| .|||. . |. | . .. |
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVV

VLGDFGIS
  .||| .
KICDFGLA
Kinase LmjF07.0170.AA Pkinase_Tyr 327-356 43 3e-06 22.05 Pfam 181-210 (270) Show / Hide 
Range on Protein: 327-356
Range on HMM: 181-210/270
Sequence Identity: 43% (13 aa)

MAPEVLQGGAASPKSDVWSLGCVLYELLAL
||||... |  . |||||| | ...|.. .
MAPECINYGKFTTKSDVWSFGVLMWEIFTY