Gene LmjF21.0130 (L.major)

LmjF21.0130

Species: L.major
Alias: LmajK187, LmjF21.0130
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
LmjF21.0130.AA Protein None 1722 None Fasta, JSON
LmjF21.0130.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of LmjF21.0130.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF21.0130.AA S_TKc 1463-1720 28 1e-67 232.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-231/231
Sequence Identity: 28% (79 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPLPSDESGMEVIEAEVLILQRVNDTHVVQLLSYAFEGDTIVIFMECMLA--GSLQNMIAAFRT-----
 .  |..|||.||.||.. . ..||.|||| ..        | |. |. ||.. .  ..|.|. .  . | . ..||..    |.|  .|   ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-IPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFGASAWLQELARKESKGEVCGTPVYLAPEAARGSPEK-ESDIWSCGIMFLQM
 .|  .|| .|. ....|  .||.|.|||| ||.|.||.   . ||.||| .. |           .|||| |.|||    .  | ..|.||||...  |
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEM

ITGRLPYSPEQLSLGAAALVYQIGSGIVQPNIPDDLDMLDAEFVRACLDDDPSKRTSAAGLLQ-------LALF
..|. |..         ......             .    .|.| ||. ||.|| .|  .||          |
LCGYPPFP-------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase LmjF21.0130.AA Pkinase 1463-1720 27 2.6e-63 221.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPLPSDESGMEVIEA---EVLILQRVNDTHVVQLLSYAFEGDTIVIFMECMLAG----SLQNMIA--AF
..  |..|.|||||||....  .|..||.| .......|..... .   |. |..|.|  ..|.|. .  ..| | . ||..  |    .|  .|   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RTI--PSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNC----KISDFGASAWLQELARKESKGEVCGTPVYLAPEAARGSPE--KESDIWS
...  .  ... .|. .||||  .||||.||||.||.|.|.. .|..    ||.||| .. .. . ...    .|||| |.|||  ||...  ...|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGIMFLQMITGRLPYSPEQ----LSLGAAALVYQIGSGIVQPNIPDD---------------------LDMLDAEFVRACLDDDPSKRTSAAGLLQLALF
||... .|..||.|.. ..      .   .....|.....  ..| .                      ...|  |.. ||. ||.|| .|. .||   |
CGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD--FIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF21.0130.AA STE 1463-1720 23 1e-57 198.05 In-house 1-359 (359) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-359/359
Sequence Identity: 23% (84 aa)

LRSTRILGKGSFGCVYLGMDA------HSGRL---------VAIKFLPLPSDE----------------SGMEVIEAEVLILQRVN--DTHVVQLLSYAF
..  ...|||.|| ||..|.       ..|..         .||| ..| ...                . |. |. |. |... |    ..|. . . |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------DTIVIFMECMLAGSLQNMIA-AFRT-------------IPSSTARVFMRDVLRG-LSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFGASA
 .       |.. |.|| | .|||  .|   . .             .| |  ... |..|.| |. |||...|||| ||.|.||     .|..||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

WLQE--------------LARKESKGEVCGTPVYLAPEAARGSPEK-------ESDIWSCGIMFLQMITGRLPYSP-EQL-SLGAAALVYQIGS-----G
 |..              . ...    ..||| . |||  ..  ..        .|||| |.. . |.||. |..    .  . ...  | ...      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

IVQ---PNIPDDLD-------------------MLDAEFVRACLDDDPSKRTSAAGLLQ--LALF
||.   | .||.|.                       .|.. ||. ||.|| .|  ||.     .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF21.0130.AA STE11 1463-1720 27 2.9e-51 176.62 In-house 1-303 (303) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-303/303
Sequence Identity: 27% (84 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPLPSDESG-------MEV------IEAEVLILQRVNDTHVVQLLSYAF---EGDTIVIFMECMLAGSL
 ..  |.|||.|| ||..|. . |.|.|.|  ..  ....       ..       |. |. ...  |  . |. .       . |.. |||| .  |||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

QNMIA-AFRT--IPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGN-CKISDFGASAWLQ-ELARKES-----------KGEVC----GTPV
  |.   . .   . .. |.. ...|.||. ||| |.||||.|. |.|| ..|| ||..|||..  |. .. ....           .|..     ||| 
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YLAPEAARGSP----EKESDIWSCGIMFLQMITGRLPYSPEQLSLGAAALVYQIGSG-IVQPNIPDDLD------MLDAEFVRACLDDDPSKRTSAAGLL
. |||  ....     . .|||| |   . |.||. |.. .. .  ..|  . ||.|   .|.||...           .|.| |.  ||.|| .|. ||
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWH-NYDH-NHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLL

QLALF
|   .
QHPFI
Kinase LmjF21.0130.AA CAMK 1468-1660 17 1.9e-43 137.42 In-house 1-334 (425) Show / Hide 
Range on Protein: 1468-1660
Range on HMM: 1-334/425
Sequence Identity: 17% (57 aa)

ILGKGSFGCVYLGMDAHSG------------RLVAIKFLP---LPSD------------------------ESGMEVIEAEVLILQR-------VNDTHV
.||.|||| |.|... ...            . ||||...   |...                        .. .. .. |. |...       ..  ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLLSYAF------------EGDT--------IVIFM---ECMLAG----SLQNMIAAF---------------RTIPSSTARVFMRDVLRGLSKLHSMG
..|. .                ..        ....|   | .  |     | ..| .                . .. . || ..| .. ..  .||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDMKPQNVLLSFT-----------------GNCKISDFGASAWLQELAR---------------------KESKGEVCGTPVYLA-PEAARG-----
..||| || |.||.                   .| ||.||| .. ...                         .   ..|||| | | ||  .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------SPE-KESDIWSCGIMFLQMITGRLPY
          .  ...|.||||..   | .|..|.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase LmjF21.0130.AA TKL 1469-1718 20 4.9e-39 136.01 In-house 1-364 (364) Show / Hide 
Range on Protein: 1469-1718
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

LGKGSFGCVYLG-MDAHS-------GRLVAIKFLPLPS-DESGM-------------------------EVIEAEVLILQRVNDTHVVQLLSYAFEGDT-
.|.|.||.|| |    ..       |. ||.| ..  . ||. .                         . .| |.... | .  ..||.. |.....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IVIFMECMLAGS-LQNMIAAFRTIPSSTARVFMRDVLRGLSKLHSMG--------VIHRDMKPQNVLLSFTGN--------------C
            . | || .  || | ...        .    ...|. ||.. ||||.        .|||| |..|.|.   ..              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KISDFGASAWLQELA-----------------RKESKGEVCGTPVYLAPEAARGSPE-----------------KESDIWSCGIMFLQMITGRLPYS--P
||.||| | ....                   ... .. .|||| ..|||. ||...                 . .|..| ||..  ..|...||.  |
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

EQLSLGA---AALVYQIGSGIVQPNIP------------DDLDMLDAEFVRACLDDDPSKRTSAAGLLQLA
.   ...    .  .....   .| ||            .| .   ..    | | ||.|| |.  .|.  
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF21.0130.AA STE20 1463-1661 28 1.7e-38 134.22 In-house 1-228 (288) Show / Hide 
Range on Protein: 1463-1661
Range on HMM: 1-228/288
Sequence Identity: 28% (65 aa)

LRSTRILGKGSFGCVYLGMDAHSGRL----VAIKFLPLPSDE---SGMEVIEAEVLILQRVNDTHVVQLLSYAFEG----DTIVIFMECMLAGSLQNMIA
   .. .|.||.| ||.. . ..|..    |||| ..| ...     .| |. |..|... .  ..|. .   . .    | . | || . .|||. .. 
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

AFR---------TIPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFGASAWLQEL---ARKESKGEVCGTPVYLAPEAARG--SP
..          ..  .   . .|.||.||. |||...|||| | .|.||.  |..|..||| .|.|...   ...  .  ..||| ..|||  ..  .|
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

EKE----SDIWSCGIMFLQMITGRLPYS
.|.    .|||| ||. . |..|. ||.
DKGYDYKCDIWSLGITAIEMAEGEPPYF
Kinase LmjF21.0130.AA STE11-Unclassified 1463-1720 27 1.3e-37 130.9 In-house 1-308 (308) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-308/308
Sequence Identity: 27% (84 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPL--PS--DESGMEV----IEAEVLILQRVNDTHVVQLLSYA--FEGDTIVIFMECMLAGSLQNMIAA
  .  ..|||||| ||..|... | ..|.| .     .  .|.  ..    |. |. .|.  |. . || .      ..| | |||| |  ||.  |.  
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

FRTIPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFGASA---------------------WLQ-ELA-RKESKGEVCGTPV---
..    ...... ...| ||. ||| |.||||.|. |.|. | |.||..|||..                       .. ...  ...  .  |||    
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

YLAPEAARGSPEK----ESDIWSCGIMFLQMITGRLPYSPEQLSL-GAAALVYQIGSGIVQPNIPDDLD---------MLDA--EFVRACLDDDPSKRTS
. |||  ..| ..     ||||| |   . |.||. |.|   ..    ..... |..    |.|| .|          ....  .| |.|.  ||.|| .
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWS--NCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPT

AAGLLQLALF
|  |||    
ANQLLQHPFI
Kinase LmjF21.0130.AA ASK 1468-1720 32 1.5e-37 122.3 In-house 1-254 (254) Show / Hide 
Range on Protein: 1468-1720
Range on HMM: 1-254/254
Sequence Identity: 32% (85 aa)

ILGKGSFGCVYLGMDAHSGRLVAIKFLPLPSDESGMEVIEAEVLILQRVNDTHVVQLLSYAFEGDTIVIFMECMLAGSLQNMIAAFRTIPS---STARVF
.||||..| || | | |  . .||| .|   ..    . | |. . ...    .|| |  . |.. . |||| .  ||| ... .         .| . .
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQPLHE-EIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFY

MRDVLRGLSKLHSMGVIHRDMKPQNVLL-SFTGNCKISDFGASAWLQELARKESKGEVCGTPVYLAPE----AARGSPEKESDIWSCGIMFLQMITGRLP
 . .| ||. ||   ..|||.|  |||.  . | .|||||| .  |  .    .     ||  |.|||      ||   |  |||| |   . | ||. |
TKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTE--TFTGTLQYMAPEVIDQGQRGY-GKPADIWSFGCTMVEMATGKPP

YSPEQLSLGAAALVYQIGSGIVQPNIPDDLDMLDAEFVRACLDDDPSKRTSAAGLLQLALF
.    |    ||. ...|   . |.||..|     .|.. | . || ||.||. |||    
F--HELGEPQAAM-FKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase LmjF21.0130.AA ULK 1463-1665 23 3.9e-37 127.19 In-house 1-263 (329) Show / Hide 
Range on Protein: 1463-1665
Range on HMM: 1-263/329
Sequence Identity: 23% (64 aa)

LRSTRILGKGSFGCVYLGMDAHS----GRLVAIKFLP-----LPSDESG----MEVIEAEVLILQRVNDT--------HVVQLLSYAFEG--DTIVIFME
    ..||||||| || | .  .    . .||.| ..       ..|.     .. .. |. |... ...        ..|.|. .  .   . | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

CMLAGSLQNMIAAFRT----------IPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFT------------GNCKISDFGASAWLQ-------
    | |.. |   ..          .. . |. |... | |.  ||....||||.||||.|..              | .||.||| .  ..       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ELARK-ESKGE-VCGTPVYLAPEAARGS-----PE-KESDIWSCGIMFLQMITGRLP---YSPEQL
 ... . |   . .|||| | ||.   |      .  ...|||| |..| .|..|. |   . ....
MMMTCVNE---KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQ
Kinase LmjF21.0130.AA Ciliate-E2 1463-1720 17 2.9e-36 121.97 In-house 1-365 (365) Show / Hide 
Range on Protein: 1463-1720
Range on HMM: 1-365/365
Sequence Identity: 17% (67 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPLPS--------------------DESGMEVIEAEVLILQRVNDTH-----------------VVQLL
    ...|.|.||.||.. .   ....|||.                          ... | |. |  |....|.                   .... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMY

SYAFE---GDTIVIFMECMLAGSLQNMIAAFRTIP-----------SSTARVFMRDVLR---------------GLSKLHSMG-VIHRDMKPQNVLLSFT
 ..|.    ..| . ||    |.|.  |  ...                .. .|. .|.               .|  ||| . .|||| ||.|.|.   
-ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

GNCKISDFGASAWLQEL--------ARKESKGEV----------------------CGTPVYLAPEAARGSPE----------KESDIWSCGIMFLQMIT
  .||.||| |  ...          .|. .                         |||| |.|||  .| ..          ...||||.|... .|..
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GRLPYSPEQLSLGAAALVYQIGSG-IVQPN----------------IPDDLDMLDAEFVRA----CLDDDPSKRTS-AAGLLQLALF
|..|.             .|.     .. .                ......     . .     .|. ||.|| . .  .|.   |
GKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF21.0130.AA ULK 1463-1661 23 8.1e-36 124.58 In-house 1-253 (324) Show / Hide 
Range on Protein: 1463-1661
Range on HMM: 1-253/324
Sequence Identity: 23% (61 aa)

LRSTRILGKGSFG-CVYLGMDAHS---GRLVAIKFLP---LPSDESG------MEVIEAEVLILQRVN---DTH--VVQLLSYAFEG--DTIVIFMECML
    ..|||||||  || | .  .   . .||.|  .   .  ...       .. .. |. |..  .     .  .|.|. .  .   . | |.||   
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGSLQNMIAAFRT---------IPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGN------------CKISDFGASAWLQELARKESKG--
 | |.. |   ..         .. . |. |... . |.  ||....||||.|||| |..                .||.|||       .|..  ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG-------FAKHVDNNNM

--EVC----------GTPVYLAPEAARGS-----PE-KESDIWSCGIMFLQMITGRLPYS
   .|          ||| | ||.   |      .  ...|||| |..| .|..|. |..
EQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFF
Kinase LmjF21.0130.AA TyrKc 1463-1718 22 9.8e-15 15.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 1463-1718
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

LRSTRILGKGSFGCVYLGMDAHSGRLVAIKFLPLPSDESGMEVIEAEVLILQRV--NDTHVVQLLSYAFEG-------DTIVIFMECMLAGSLQNMIAAF
..  ..|| | || ||.|.     . ||.| |   .    .| .  |  |. ..  .  ..|.|. .. ..       . . | || |  |.|.. . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RT-IPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFGASAWLQELARKESKG--------EVC-----GTP--V---YLAPEAA-
|  .. ..   |. .. .| . |||...||||    |.|..  . .||||||       |.|.   .                |.   .    .|||.  
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFG-------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

RGSPEKESDIWSCGIMFLQMIT-GRLPYSPE--QLSLGAAALVYQIGSGIVQPNIPD--------DLDMLDAEFVRACLDDDPSKRTSAAGLLQLA
 |    .||.|| |..   . | |  ||. .  |  . .. .. .. .|   |  |.          | .     . | . ||..| . . . .. 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF21.0130.AA Pkinase_Tyr 1463-1604 25 4.1e-09 31.48 Pfam 1-156 (270) Show / Hide 
Range on Protein: 1463-1604
Range on HMM: 1-156/270
Sequence Identity: 25% (39 aa)

LRSTRILGKGSFGCVYLGMDA----HSGRLVAIKFLPLPSDESG--MEVIEAEVLILQRV-NDTHVVQLLSYAF-EGDT--IVIFMECMLAGSLQNMIAA
..  . ||.|.|| ||.|         .  ||.| |.  ....   .|   .|. |.    .  ..|.|.     .|.   | | || |  |.| .   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----FRTIPSSTARVFMRDVLRGLSKLHSMGVIHRDMKPQNVLLSFTGNCKISDFG
     . .. ..   . ... .|.. |.|.. ||||    |.|.. .. .||.|||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase LmjF21.0130.AA STE20 1695-1720 42 0.001292 9.43 In-house 263-288 (288) Show / Hide 
Range on Protein: 1695-1720
Range on HMM: 263-288/288
Sequence Identity: 42% (11 aa)

EFVRACLDDDPSKRTSAAGLLQLALF
.||  ||. ||.|| .|  ||.   .
DFVDKCLQKDPEKRPTASQLLKHPFI