Gene LmjF05.0390 (L.major)

LmjF05.0390

Species: L.major
Alias: LmjF05.0390, LmajK192
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF05.0390.AA Protein None 719 None Fasta, JSON
LmjF05.0390.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of LmjF05.0390.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MORN LmjF05.0390.AA MORN 145-166 63 1.6e-12 48.86 SMART 1-22 (22) Show / Hide 
Range on Protein: 145-166
Range on HMM: 1-22/22
Sequence Identity: 63% (14 aa)

DTYEGEWLNGMMHGKGTYTWAD
|.||||| ||..||.|.|.||.
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 147-169 73 3.1e-11 45.54 Pfam 1-23 (23) Show / Hide 
Range on Protein: 147-169
Range on HMM: 1-23/23
Sequence Identity: 73% (17 aa)

YEGEWLNGMMHGKGTYTWADGDY
||||| ||.|||.|.|||.|||.
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 260-281 54 3.4e-09 37.8 SMART 1-22 (22) Show / Hide 
Range on Protein: 260-281
Range on HMM: 1-22/22
Sequence Identity: 54% (12 aa)

DVYEGEFARGKPNGRGTYLWAD
|.||||. .||. |.|.| ||.
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 262-284 56 3.6e-09 38.05 Pfam 1-23 (23) Show / Hide 
Range on Protein: 262-284
Range on HMM: 1-23/23
Sequence Identity: 56% (13 aa)

YEGEFARGKPNGRGTYLWADGAR
||||. .||..|.|.| |.|| |
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 192-214 30 2e-06 27.79 Pfam 1-23 (23) Show / Hide 
Range on Protein: 192-214
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

YTGEWADDMRQGYGRMLYAGGNV
| ||| .....|.|.. .. |..
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 213-234 45 6e-06 27.08 SMART 1-22 (22) Show / Hide 
Range on Protein: 213-234
Range on HMM: 1-22/22
Sequence Identity: 45% (10 aa)

NVYEGEWLAGMRHGSGKLVEPA
..||||| .|.||| |... . 
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 239-261 47 7e-06 26.15 Pfam 1-23 (23) Show / Hide 
Range on Protein: 239-261
Range on HMM: 1-23/23
Sequence Identity: 47% (11 aa)

YEGEFNRNEKEGRGVQTNSDGDV
||||. .. ..|.|| | .|||.
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 190-211 36 2.9e-05 24.72 SMART 1-22 (22) Show / Hide 
Range on Protein: 190-211
Range on HMM: 1-22/22
Sequence Identity: 36% (8 aa)

GLYTGEWADDMRQGYGRMLYAG
  |.||| ...|.|.|.. .| 
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 283-304 45 5.6e-05 23.78 SMART 1-22 (22) Show / Hide 
Range on Protein: 283-304
Range on HMM: 1-22/22
Sequence Identity: 45% (10 aa)

ARYIGMFKDGVKHGDGCEWLAN
.||.| ...| .|| |. | ||
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 215-237 43 6.8e-05 22.52 Pfam 1-23 (23) Show / Hide 
Range on Protein: 215-237
Range on HMM: 1-23/23
Sequence Identity: 43% (10 aa)

YEGEWLAGMRHGSGKLVEPAAHV
|||||  |..||.|... |   .
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 285-307 39 8.6e-05 22.16 Pfam 1-23 (23) Show / Hide 
Range on Protein: 285-307
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

YIGMFKDGVKHGDGCEWLANGDW
| | .|.|..|| |. . ..|| 
YEGEWKNGKMHGHGVYTWPDGDR
MORN LmjF05.0390.AA MORN 237-258 31 0.000663 18.16 SMART 1-22 (22) Show / Hide 
Range on Protein: 237-258
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

VMYEGEFNRNEKEGRGVQTNSD
 .||||. .. . |.|| . ..
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 170-190 33 0.001156 18.06 Pfam 1-21 (23) Show / Hide 
Range on Protein: 170-190
Range on HMM: 1-21/23
Sequence Identity: 33% (7 aa)

YQGDYVRGRMEGRGEMKDATG
|.|....|.|.|.| .. ..|
YEGEWKNGKMHGHGVYTWPDG
MORN LmjF05.0390.AA MORN 168-189 31 0.002304 14.11 SMART 1-22 (22) Show / Hide 
Range on Protein: 168-189
Range on HMM: 1-22/22
Sequence Identity: 31% (7 aa)

DYYQGDYVRGRMEGRGEMKDAT
| |.|....|.. |.| .  | 
DRYEGEWHNGKRHGHGVYWWAN
MORN LmjF05.0390.AA MORN 123-146 45 0.027387 13.07 Pfam 1-23 (23) Show / Hide 
Range on Protein: 123-146
Range on HMM: 1-23/23
Sequence Identity: 45% (11 aa)

YVGTIDENGEMAGYGKATWHSGDT
| |.   || | |.|. || .||.
YEGEW-KNGKMHGHGVYTWPDGDR
Kinase LmjF05.0390.AA STE11 449-711 40 2.9e-110 372.63 In-house 1-303 (303) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-303/303
Sequence Identity: 40% (124 aa)

WTPLKTIGKGSFGAVYTALLRN-GRTVCCKVIELGTVES-----EEEMDK------LRNEIALMRRLRHPNCVQYYG-SLEDKVKNTLNIFMEYVSGGTL
|.  . ||||.|| ||...  . |. .  | ||..  ..     |.|...      .. ||.||. |.|.| |.||| .|.|  ....||||||..||.|
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

TSFVT-KFKS--IPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGI-VKLADFGCSKAIDDVCSATHG-------CSTMVGTPY--------
 |    |.     .  . |. . |   |..|||. ||.||||||.|.|.  ||. .|||||||.| .   |. ||.       | .| ||||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVIKCEA-GGYGVKSDIWSIGCTIVEMLTGKPPWPECNS-MWAAVYKIANSTGLPTEIPADID------PKLMDLLQKCFERDPKLRPTAAGMLSH
|||||||| |  .||| |.||||.|||..||.||||||.....  .|| .||. . . . .|| ..       ....| |..|||.||| ||||.  | |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFL
||.
PFI
Kinase LmjF05.0390.AA S_TKc 449-711 31 1.9e-98 334.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-231/231
Sequence Identity: 31% (89 aa)

WTPLKTIGKGSFGAVYTALLRN-GRTVCCKVIELGTVESEEEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSG--GTLTSFVTKFKS-
.. |..||||.|| || .  .. || | .|.|           ...|.||..... .||| |..|.. .|   . | ..|||..|  |.| ..  | .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----IPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAIDDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGV-KSDIWS
     .|  . | ..||..|...|.|. ||.|||.| .|.|..    .|..||| .. .          .|..|||..|||||.     |||  |.|.||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-----GYGKCKCDWWS

IGCTIVEMLTGKPPWPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLS-------HPFL
.||.. |||.|.||.|      ....|.              .| . |...||...||. ||||   |        ||..
CGCILYEMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF05.0390.AA STE 449-711 29 8.4e-98 331.22 In-house 1-359 (359) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-359/359
Sequence Identity: 29% (106 aa)

WTPLKTIGKGSFGAVYTALLRN----------------GRTVCCKVIELGTVES--------------EEEMDKLRNEIALMRRLR--HPNCVQYYGSLE
|. .. ||||.|| ||.|. ..                |. .  |...| . ..              .|||... .|| .|....  ||| |.|||. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DKVKNTLNIFMEYVSGGTLTSFVT-KFKS-------------IPLETLRQWVYQMVCG-VKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSK
     .| ...|.|.|||..||.|....  |..              .| . ..  ..| . |  .|||. .|.|||||..|.|.     |||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

AIDDVCS------------ATH-GCSTMVGTPYWMAPEVIKCE----AGGYGVKSDIWSIGCTIVEMLTGKPPWPECNSM---WAAVYKIANST------
 ..| ..             .   . |.|||| |||||||...     .||..|.||||.||||.||.|||||| . . |   ...  ... .       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GLPTEIPADID-------------------PKLMDLLQKCFERDPKLRPTAAGMLS--HPFL
   | |  .| ...                   |.. | ..||...||. ||||  .|.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF05.0390.AA STE11-Unclassified 449-711 37 4.4e-92 312.21 In-house 1-308 (308) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-308/308
Sequence Identity: 37% (117 aa)

WTPLKTIGKGSFGAVYTAL-LRNGRTVCCKVIEL-GTV----ESEEE-MDKLRNEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSGGTLTSFVTK
|   . |||||||.||... . .|  .  | ||  ..     . ..|  . .. |..... |.|.| |||||  ..| .. .||||||..|| . |   |
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

FKSIPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAID------------------DVCSAT----HGCSTMVGTPY---
.     .. .  . |   |..|||. ||.||||||.|.|.  |||.||.||||.| |.                    |...      | .| ||||   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WMAPEVIK-CEAGGYGVKSDIWSIGCTIVEMLTGKPPWPECNS--MWAAVYKIANSTGLPTEIPADID-----------PKLMDLLQKCFERDPKLRPTA
||||||||    .|.. ||||||.|||..|| |||.||. |.     .|..||..|   | .|| .             ....|.|.|||..||| ||||
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIP-QIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTA

AGMLSHPFL
   |.|||.
NQLLQHPFI
Kinase LmjF05.0390.AA Pkinase 449-711 30 6.9e-86 296.43 Pfam 1-293 (293) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

WTPLKTIGKGSFGAVYTALLRNGRT-VCCKVIELGTVESEEEMDKLR-NEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSGG----TLTSFVT--
.. ...||.|||| || .  .. .  |..|.|.. . .|.... ..| .||..|.||.||| |..|.. ||  |. . . |||. ||     | ....  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

KFKSI--PLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIV----KLADFGCSKAIDDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGVKS
. ...  . .... ..||...|..|.|..||.|||.| .|.|.. .| .    |..|||..| .|   . .  ..| .|||..||||||. .. .|| |.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS--MTTFCGTPWYMAPEVIR-GGQYYGPKV

DIWSIGCTIVEMLTGKPPWPEC------NSMWAAVYKIANSTGLPTEIPADID-----------------PKLMDLLQKCFERDPKLRPTAAGMLSHPFL
|.||.||.. |||.|.||.|..      . |.  . .    .  . . . .|                  . . |.. .|...||| ||||.  | ||..
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF05.0390.AA MEKK2 449-711 42 2.3e-78 266.66 In-house 1-262 (262) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-262/262
Sequence Identity: 42% (112 aa)

WTPLKTIGKGSFGAVYTAL-LRNGRTVCCKVIELG--TVESEEEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSGGTLTSFVTKFKSI
|   | .|.| || ||       || .  | ..      |.  |.. |. || |.. |.|.  ||||| |.|. . || |||||..|| .   .  . ..
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGAL

PLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAIDDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGVKSDIWSIGCTIVE
  .  |..  |.. |..|||.  |||||||| |.|    | |||.||| || .  .|.   |  .. ||||||.||||  |  ||| | |.||||||.||
TETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGE--GYGRKADVWSIGCTVVE

MLTGKPPWPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
||| |||| |   | ||..|||     | ..|  .  .  | |..|| .  . || |. .| | | 
MLTEKPPWAEYEAM-AAIFKIATQPTNP-QLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase LmjF05.0390.AA MEKK15 449-711 40 4.4e-77 262.39 In-house 1-264 (264) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-264/264
Sequence Identity: 40% (110 aa)

WTPLKTIGKGSFGAVYTALLRNGRTVCCKVIELGTVE---SEEEMDKLRNEIALMRRLRHPNCVQYYG-SLEDKVKNTLNIFMEYVSGGTLTSFVTKFKS
|.  . .||| .| ||  |   |  .  | .|| ...   ....  ||  |. |.. |.| | | | | .|||   |..||||..| || ..| . .| .
WKKGNILGKGAYGTVYCGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLED---NVVNIFMQFVPGGSISSIINRFGP

IPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAIDDV-CSATH--GCSTMVGTPYWMAPEVIKCEAGGYGVKSDIWSIGC
..     ..  |.. ||.||||  .||||||| ||..   ||.|| |||| | .     . ||      | |||||||||||.    ||| |||||||||
LDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIM--ETGYGRKSDIWSIGC

TIVEMLTGKPPWPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
|. || |.|||| . . | ||.. |    ..  ..|.    .  .  . |  || . ||||  .| |||.
TVFEMATRKPPWADMDRM-AAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase LmjF05.0390.AA STE20 449-711 36 1.1e-75 257.77 In-house 1-288 (288) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-288/288
Sequence Identity: 36% (107 aa)

WTPLKTIGKGSFGAVYTALL-RNGRT----VCCKVIELGTVESE-EEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVK--NTLNIFMEYVSGGTLTSFVT
.. |. ||.||.|.||.|   ..|.     |. |...| . . | .|.. . .||  |....||| |.||||   . .  . | | ||| .||.||  ..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

KFKSIPL---------ETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAIDD--VCSATHGCS--TMVGTPYWMAPEVIKCEA
.. ..           |      .... | .|||. .|.|||||.||.|.. || ||||||| .  ...      | ..   |.||||||||||||.|. 
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

---GGYGVKSDIWSIGCTIVEMLTGKPPWPECNSMWAAVYKIANSTGLPTEI---PADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
   .||. |.|||| | |. ||..|.||  ... | |  ... |. . ||     |    |.. |.. || ..||. ||||  .|.|||.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF05.0390.AA CAMK 454-711 18 1.1e-69 223.47 In-house 1-425 (425) Show / Hide 
Range on Protein: 454-711
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

TIGKGSFGAVYTALLR-NG------------RTVCCKVIELGTVES-------------------------EEEMDKLRNEIALMRR-------LRHPNC
|.|.|||| |. .  . ..            . | .|.|.   . .                         .. ....|.||..|..       |.||| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYYGSLEDKV-----------------KNTLNIFM---EYVSGG----TLTSFVTKFKS---------------IPLETLRQWVYQMVCGVKYLHECGI
.. |   ||.                  .. . ..|   ||.|||     | ..... ..               .. .  |... |....|.|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKGDNVLVSVD-----------------GIVKLADFGCSKAIDDVC--------------------SATHGCSTMVGTPYWMA-PEVIKCE-----
||||.| .|.|.. .                 . .|..||| .. .|.                        .. ..|..|||. || |||.. .     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------AGGYGVKSDIWSIGCTIVEMLTGKPPWPEC---------------NSMWAAVYKIANSTGLPT--EIPAD----------------IDPKLMD
         .|| |.|.||.|.    ||.|.||. .                . ..  . |   .   |   .|...                ...  .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLQKCFERDPKLRPTAAGMLSHPFL
|..|. ..||. |.|..  |.||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF05.0390.AA ASK 455-711 40 2.7e-67 222.82 In-house 2-254 (254) Show / Hide 
Range on Protein: 455-711
Range on HMM: 2-254/254
Sequence Identity: 40% (106 aa)

IGKGSFGAVYTAL-LRNGRTVCCKVIELGTVESEEEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSGGTLTSFVTKFKSIPLE----T
.|||..| || .  ... . .  | |.   .  ...   | .|||| ..||| | ||| |.  .   . . |||| | || | . . . |  |..    |
LGKGTYGIVYAGRDMHTQVRIAIKEIP---ERDSRYVQPLHEEIALHKQLRHRNIVQYLGC--CSENGYFKIFMEQVPGGSLSALL-RSKWGPMKDNENT

LRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSV-DGIVKLADFGCSKAIDDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGVKSDIWSIGCTIVEMLT
.. .  |.. |.|||||  |||||||||||||    |.||..||| .| .  .  .|   .|  ||  .||||||     |||   ||||.|||.||| |
MNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCT---ETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMAT

GKPPWPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
||||. |  .  ||..|.      | ||| ..  .  . . .||| ||. |..|. .|  |||
GKPPFHELGEPQAAMFKVGMYKKHP-EIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase LmjF05.0390.AA Dicty2 455-711 39 1.3e-66 227.58 In-house 8-264 (264) Show / Hide 
Range on Protein: 455-711
Range on HMM: 8-264/264
Sequence Identity: 39% (106 aa)

IGKGSFGAVYTAL-LRNGRTVCCKVIE---LGTVESEEEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVKNTLNIFMEYVSGGTLTSFVTKFKSIPLETL
|||| || || .|    |  |  | |.     |  |||    . .|| | ..|.|.| | |... |  ..| |.|..||. .| |   . ||   | . .
IGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIE--TENHLYIILEYIENGSLSKIIKKFGCFPESLC

RQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGI---VKLADFG-CSKAI-DDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGVKSDIWSIGCTIVE
   .||.  |  |||. |..|||||..| |.. .|    .|||||| ... . .|  |..    | ||||||||||||    .    ..|||| |||| |
CIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRY----TVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTIIE

MLTGKPPWPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
.||| ||    | | .| ... .    |  .| || | . | |. || .|| .|.||   |.|| .
LLTGNPPYWDLNPM-HAMFRMVQDDHPP--LPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase LmjF05.0390.AA TKL 455-709 22 3e-64 219.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 455-709
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

IGKGSFGAVYTALLRN---------GRTVCCKVIELGTV------------------------ESEEEMDKLRNEIALMRRLRHPNCVQYYGSLEDKVKN
||.|.|| || . .|.         |..|  |..    .                        |.. .......|| .|.|||||| ||..|.  .  ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

T-----------LNIFMEYVSGGTLTSFVTKFKSIPLETLRQWVYQMVCGVKYLHECG--------IVHRDIKGDNVLVSVDGI--------------VK
.           | | |||..||.| ....      .. . .|.... .|. ||| ..        |.|||.| .|.||  ..               .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LADFGCSKAIDDVCSATHGCST----------------MVGTPYWMAPEVIK--------------CEAGGYGVKSDIWSIGCTIVEMLTGKPPWP-ECN
..||| |. ..   . ... .|                 .|||.||||||..              |. . |  |.|..| |  . |.||...|.  . .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

SMWA------AVYKIANSTGLPTEIP------------ADIDPKLMDLLQKCFERDPKLRPTAAGMLSHP
...       .  ... . ||. .||             |..| . .|.|.| . ||. ||..   |.. 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF05.0390.AA TyrKc 449-711 26 1.2e-30 109.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 449-711
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

WTPLKTIGKGSFGAVYTALLRNGRTVCCKVIELGTVESEEEMDKLRNEIALMRRL--RHPNCVQYYGSLEDK-----VKNTLNIFMEYVSGGTLTSFVTK
 | .|..| | || || . ..  ..|  |..  ..      .  ...|. .|..|  .||| |. ||   ..         | | |||...| | ..  |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

FKS-IPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAI----------DDVCSATHGCSTMVGTPYWMAPEVIKCEAGGY
 .  .....| .. .|  ||  |||. ...|||.   |.||. ...|| .||| |..|          |   ...|... ..    |||||.|    | .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

GVKSDIWSIGCTIVEMLT-GKPPWPEC----NSMWAAVYKIANSTGLPTEIPAD--------IDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
  |||.|| | .. |..| |..|.|.      |   .. .. .   .|  .|..          ... .. ..| ..||. ||| .    | ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP--QPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF05.0390.AA Pkinase_Tyr 452-711 28 4.9e-30 102.36 Pfam 4-270 (270) Show / Hide 
Range on Protein: 452-711
Range on HMM: 4-270/270
Sequence Identity: 28% (79 aa)

LKTIGKGSFGAVYTALLR-----NGRTVCCKVIELGTVESEE-EMDKLRNEIALMRRL-RHPNCVQYYGSLEDKVKN-TLNIFMEYVSGGTLTSFVTK--
.|..|.|.|| || . ..     .. .|  |..   .  .|.  .... .|...|. | .||| |..||   |. .   . | |||. .| | ..  |  
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

--FKSIPLETLRQWVYQMVCGVKYLHECGIVHRDIKGDNVLVSVDGIVKLADFGCSKAI--DDVCSATHGCSTMVGTPYWMAPEVIKCEAGGYGVKSDIW
   .......| |. .|  .|  ||.. ...|||.   |.||. ...|| .||| ...|  ||    . . ...     |||||.|.   | . .|||.|
EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECIN--YGKFTTKSDVW

SIGCTIVEMLT-GKPP-WPECNSMWAAVYKIANSTGLPTEIPADIDPKLMDLLQKCFERDPKLRPTAAGMLSHPFL
| | .. |..| |. | .|..    . ||.     |   ..| .  ... ||...| . ||. ||| .    | .|
SFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL