Gene LmjF33.1400 (L.major)

LmjF33.1400

Species: L.major
Alias: LmajK214, LmjF33.1400
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF33.1400.AA Protein None 1954 None Fasta, JSON
LmjF33.1400.kin_dom Protein Kinase Domain None 566 None Fasta, JSON

Protein domain

Protein domains of LmjF33.1400.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA LmjF33.1400.AA FHA 196-231 40 3.2e-07 31.27 Pfam 34-73 (73) Show / Hide 
Range on Protein: 196-231
Range on HMM: 34-73/73
Sequence Identity: 40% (16 aa)

RVSLTD--CSANGTYV--NGVLVGRGKCCDLHYGDDISIV
|. ..|  || |||.|  ||. ...|. ..|| || |.. 
RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA LmjF33.1400.AA FHA 68-95 38 3.8e-05 23.38 Pfam 1-31 (73) Show / Hide 
Range on Protein: 68-95
Range on HMM: 1-31/73
Sequence Identity: 38% (12 aa)

VRVGRAGGCDTVLS-DPR-VSSTHFTI-SLE
...||.  || ||. ||. ||  |..| ...
WTIGRDPDCDIVLDNDPSFVSRHHCEIRRYD
FHA LmjF33.1400.AA FHA 67-214 12 0.000798 19.65 SMART 1-49 (49) Show / Hide 
Range on Protein: 67-214
Range on HMM: 1-49/49
Sequence Identity: 12% (19 aa)

TVRVGRAGGCDTVLSDPRVSSTHFTISLELEPYGNSDHRNHRRGGGDHETPWLLRRSPKGSPAHTRGIHADANDDVASGADVPGSAVPGGLASSSSLSSP
|...||.  || .|..| .|  |..|.   ...                                                                   
TWTIGRHS-CDIQLPHPSISRHHCQIR---DGD-------------------------------------------------------------------

AAAGKGLNKDGRSDARALSGTTLPGWRVSRVSLTDCS---ANGTYVNGVLV
                                . |..    |||||||. |
-------------------------------YIIDLGEHSTNGTYVNGRRV
S_TKc LmjF33.1400.AA S_TKc 615-1180 14 1.4e-67 231.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 615-1180
Range on HMM: 1-231/231
Sequence Identity: 14% (82 aa)

LQWGGRIGFGASGDVFMGIDVSTATVVAIKVLKGSSLFQSSQPADTAVAKAHSKTTSGRPAVPSVQDDGTILNLSNISLGNGAVADPRAASEGWTCASHA
 . .  || || | |. .....|  .||||..|                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

LASPMTLSSHCATSLQVNHANEESIQISEASTPLTPASAVTSSSASAHGNTSAALVNMSSTPHCHTQVQQQQPPRPQSQDEHSASPLLRKHLREIIFLTT
                                                                                        .. .|||  |  
----------------------------------------------------------------------------------------EHIRREIQILKK

LQHRRIVRFLGFQFSGEGRLCLLMEYVAG--GTLQTLVKNFGV------FEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSSVKLTDFGTS
 .|  ||.....  .  ..|.. |||. |  |.| .. |. |       | | ..| |. ||...|||. ..|..| ||| .|||..|   .|..||| .
-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLA

RFLRVCAAEEKGAGEAAGADDERPGAEVRRARRRGESREIRHAPADRAHKRYHHASSPGADAAVEEDSRGEDIGVGNAEGCGDCCRGGSDEDAYSDDIHS
|.|                                                                                                 
RQL-------------------------------------------------------------------------------------------------

AEGTFEEDEEREDLNEDVGPERRLLCGTPLYMSPELIRTQEPTF-ASDMWALGCVVYEMATGGVLPWRPVHNLSAPAVIWYIGQRGEEGDGPSMDDVYTE
                      . .|||| ||.||..     .. ..|.|..||..|||.. |  |..       ..... .                  
----------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP------QMQMMFKKIG----------------

RDRLNRASTDPSLHESVDDSYDEGGGRRGHSSRGGSGGRWDRTPSPMLLDLLQSTLNMNPALRPTPVELLQ-------HPFI
                                            || ..|...  |...|. |||  |.||       ||..
--------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF33.1400.AA STE 786-1067 19 1.9e-45 157.31 In-house 59-264 (359) Show / Hide 
Range on Protein: 786-1067
Range on HMM: 59-264/359
Sequence Identity: 19% (63 aa)

QPPRPQSQDEHSASPLLRKHLREIIFLTTLQ--HRRIVRFLGFQFSG------EGRLCLLMEYVAGGTLQTLVK-NFGVFE-------------ENVIRL
| .  | ..| . .  . . |.|| ..  ..  |  ||...|  | .      .. |.. |||..||.|  ..| ..|...             |..|. 
Q-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY

YTLQILEG-LEYLKRKGVVHGDLKSANILVSEQSSVKLTDFGTSRFLRV------------CAAEEKGAGEAAGADDERPGAEVRRARRRGESREIRHAP
.. |||.| |.|| .....| |.|.||||.     |||.|||..  |              |                                      
ICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDC--------------------------------------

ADRAHKRYHHASSPGADAAVEEDSRGEDIGVGNAEGCGDCCRGGSDEDAYSDDIHSAEGTFEEDEEREDLNEDVGPERRLLCGTPLYMSPELIRTQEPT-
                                                                       |. . .|  ..||| .|.|| |. .. . 
---------------------------------------------------------------------I-ETMQQKRNTFVGTP-WMAPEVIQQNGQGR

-----FASDMWALGCVVYEMATG
     . .|.| |||.. |||||
DKGYDTKCDIWSLGCTIIEMATG
Kinase LmjF33.1400.AA CAMK 806-1067 13 3.2e-39 123.56 In-house 79-330 (425) Show / Hide 
Range on Protein: 806-1067
Range on HMM: 79-330/425
Sequence Identity: 13% (49 aa)

LREIIFLTTLQ-------HRRIVRFLGFQF------------SGEG-------RLCLLM---EYVAGG----TLQTLVKNF---------------GVFE
.|||  . .||       |. |.... .              . .        .... |   ||. ||     |   ..                 | |.
RREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFT

ENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQS-----------------SVKLTDFGTSRFLR-------------------VCAAEEKGAGE
|   | |  ||.....|.  ...|| |||  |||... .                  .|..||| .....                   .          
EREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW----------

AAGADDERPGAEVRRARRRGESREIRHAPADRAHKRYHHASSPGADAAVEEDSRGEDIGVGNAEGCGDCCRGGSDEDAYSDDIHSAEGTFEEDEEREDLN
                                                                                                    
----------------------------------------------------------------------------------------------------

EDV--GPERRLLCGTPLYMS-PELIRT-------------QEP-TFASDMWALGCVVYEMATG
 ..  |.  .  |||| ||. ||...              ... ....|||..|.. | | .|
TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCG
Kinase LmjF33.1400.AA STE11 808-907 40 9.9e-37 128.35 In-house 60-165 (303) Show / Hide 
Range on Protein: 808-907
Range on HMM: 60-165/303
Sequence Identity: 40% (43 aa)

EIIFLTTLQHRRIVRFLGFQFS--GEGRLCLLMEYVAGGTLQTLVK-NFGV--FEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSS-VKLT
||  . .|.| .|||..|.. .   .. ..  |||..||.|  . . ..|   |.|.||| || |||||| ||  .|..| |.| ||||.  ..  .||.
EIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLA

DFGTSR
|||...
DFGCAK
Kinase LmjF33.1400.AA Ciliate-E2-Unclassified 826-1067 16 6.7e-35 118.5 In-house 88-266 (352) Show / Hide 
Range on Protein: 826-1067
Range on HMM: 88-266/352
Sequence Identity: 16% (48 aa)

FQFSGEGRLCLLMEYVAGGTLQTLVKNFGV-----------------FEENVIR-----LYTLQILEGLEYLKRKG-VVHGDLKSANILVSEQS---SVK
..|  .  ... |||. ||.|.   |...                  |.|. ..      |. |||.||||| .|. ..| |.|  |||....     .|
YCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIK

LTDFGTSRFLRVCAAEEKGAGEAAGADDERPGAEVRRARRRGESREIRHAPADRAHKRYHHASSPGADAAVEEDSRGEDIGVGNAEGCGDCCRGGSDEDA
..||| |...  .  .. . .                                                                               
IIDFGISKKYQQNNNCD-TNQ-------------------------------------------------------------------------------

YSDDIHSAEGTFEEDEEREDLNEDVGPERRLL--------------CGTPLYM----SPELIRTQEPT----FASDMWALGCVVYEMATG
                               .              |||| ||    .||... |..     ...|.|.||.. ||| .|
-------------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase LmjF33.1400.AA STE11-Unclassified 808-907 41 1.2e-31 109.48 In-house 55-155 (308) Show / Hide 
Range on Protein: 808-907
Range on HMM: 55-155/308
Sequence Identity: 41% (42 aa)

EIIFLTTLQHRRIVRFLGFQ-FSGEGRLCLLMEYVAGGTLQTLVKNFGVFEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSSVKLTDFGTS
|.  | .| |  ||. .|..    |. ... |||..|| .  . ...| |.|.||. || ||||||.||  .|..| |.| ||||.  .  .||||||..
EMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNKYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCA

R
.
K
Kinase LmjF33.1400.AA Pkinase 803-909 31 1.3e-27 98.74 Pfam 43-162 (293) Show / Hide 
Range on Protein: 803-909
Range on HMM: 43-162/293
Sequence Identity: 31% (38 aa)

RKHLR--EIIFLTTLQHRRIVRFLGFQFSGEGRLCLLMEYVAGG----TLQTLVK--NFGVF--EENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILV
. |.|  ||  .  |.|  |||....  . ...... |||. ||     | ....  . |.|  .|.... | .|||.||||. ..|..| |||..|||.
QTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI

SEQSSV----KLTDFGTSRFL
...  .    |..||| ....
DNNGHIDACVKICDFGLAKQF
Kinase LmjF33.1400.AA Dicty2 808-905 39 1.5e-25 86.01 In-house 53-152 (264) Show / Hide 
Range on Protein: 808-905
Range on HMM: 53-152/264
Sequence Identity: 39% (40 aa)

EIIFLTTLQHRRIVRFLGFQFSGEGRLCLLMEYVAGGTLQTLVKNFGVFEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSS---VKLTDFG
||  | .|.|  ||.....  . |  |   .||. .| | . .|.|| | |  .  |  |.|.||.|| |.||.| | |.||||..   .   .||.|||
EIHLLKKLNHHNIVKYIEHIET-ENHLYIILEYIENGSLSKIIKKFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFG

T
.
V
Kinase LmjF33.1400.AA TKL 621-909 13 2.9e-24 84.28 In-house 1-204 (364) Show / Hide 
Range on Protein: 621-909
Range on HMM: 1-204/364
Sequence Identity: 13% (49 aa)

IGFGASGDVFMGIDVSTA--------TVVAIKVLKG------------------SSLFQSSQPADTAVAKAHSKTTSGRPAVPSVQDDGTILNLSNISLG
|| |..| |. |.   .         ..||.|..|                   .                                             
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNY---------------------------------------------

NGAVADPRAASEGWTCASHALASPMTLSSHCATSLQVNHANEESIQISEASTPLTPASAVTSSSASAHGNTSAALVNMSSTPHCHTQVQQQQPPRPQSQD
                                                                                                    
----------------------------------------------------------------------------------------------------

EHSASP---------LLRKHLREIIFLTTLQHRRIVRFLGFQFSGEGR------------LCLLMEYVAGGTLQTLVKNFGVFEENVIRLYTLQILEGLE
  |. .         .  .  .||  .  |.|  ||.|.|. ......            ||. |||. ||.|  ..        ...    |.|  |..
--SD-MQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMN

YLKR--------KGVVHGDLKSANILVSEQSS--------------VKLTDFGTSRFL
||          ....| ||||.|||| |                 .|..|||.|||.
YLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFM
Kinase LmjF33.1400.AA Ciliate-E2 806-909 26 3.3e-24 80.0 In-house 70-206 (365) Show / Hide 
Range on Protein: 806-909
Range on HMM: 70-206/365
Sequence Identity: 26% (38 aa)

LREII----------FLTTLQHRRIVRFLGFQFS-GEGRLCLLMEYVAGGTLQTLVKNF-----------GVFEENVIRLYTLQILE-------------
.|||            | .|.|  |...  .  .  .  . | |||. ||.|. . ||.           . | |. |. .. |||.             
MREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACI

--GLEYLKRKG-VVHGDLKSANILVSEQSSVKLTDFGTSRFL
  .||||. |. ..| |.|  |||.     .|..|||.|...
ILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKY
Kinase LmjF33.1400.AA Pkinase 1031-1180 23 5.8e-24 85.81 Pfam 171-293 (293) Show / Hide 
Range on Protein: 1031-1180
Range on HMM: 171-293/293
Sequence Identity: 23% (37 aa)

LCGTPLYMSPELIR-TQEPTFASDMWALGCVVYEMATGGVLPWRPV----HNLSAPAVIWYIGQRGEEGDGPSMDDVYTERDRLNRASTDPSLHESVDDS
.|||| ||.||.||  |. . ..|||..||..|||.. | .|..      . ..  ..|  |...  . | |  ...... .|  . .            
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H------------

YDEGGGRRGHSSRGGSGGRWDRTPS--PMLLDLLQSTLNMNPALRPTPVELLQHPFI
                  .| . .   . ..|.. . |...|. |||. ..||||..
----------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF33.1400.AA CMGC 806-909 19 1.8e-21 66.45 In-house 69-254 (513) Show / Hide 
Range on Protein: 806-909
Range on HMM: 69-254/513
Sequence Identity: 19% (36 aa)

LREIIFLTTLQ----------------HRR-IVRFLGFQFSGE----------------GRLCLLMEYVAGGTLQTLVKNFG---------VFEENV---
|||| .|  |.                |.  ||. . .  . .                  |.| .||. . .|  . ||            ..| .   
LREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM-DHDLYQYIKNNQFDYQGKRPMPLSE-HENK

---------IRLYT------LQILEGLE--YLKRKG--VVHGDLKSANILVSEQSSV--------------------KLTDFGTSRFL
         |. ..       |||.||.  |. ...  ..| ||| .|||....  .                    |. ||| .|..
HPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWY
Kinase LmjF33.1400.AA STE20 795-909 26 7.5e-21 73.16 In-house 37-167 (288) Show / Hide 
Range on Protein: 795-909
Range on HMM: 37-167/288
Sequence Identity: 26% (35 aa)

EHSAS----PLLRKHLREIIFLTTLQHRRIVRFLGFQFSG---EGRLCLLMEYVAGGTLQTLVKNFG---------VFEENVIRLYTLQILEGLEYLKRK
...      . .. .. || ..  ..|  ||...|  . .   .  | ..||| .||.|. ..|..          ...|  |   . ..|.||.|| ..
NLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSN

GVVHGDLKSANILVSEQSSVKLTDFGTSRFL
...| |.|..|||..|. .|||.||| .  |
HIIHRDIKADNILLTEDGEVKLADFGVCAQL
Kinase LmjF33.1400.AA STE11-Unclassified 1033-1180 23 1.7e-20 69.37 In-house 194-308 (308) Show / Hide 
Range on Protein: 1033-1180
Range on HMM: 194-308/308
Sequence Identity: 23% (39 aa)

GTPL---YMSPELIRT--QEPTF-ASDMWALGCVVYEMATGGVLPWRPVHNLSA---PAVIWYIGQRGEEGDGPSMDD-------VYTERDRLNRASTDP
|||    .|.||.|..  |. .  .|| |.|||.|.|||||     .|  |...   ...| .|.  ..    |. .                       
GTPYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATG----KHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISC--------------

SLHESVDDSYDEGGGRRGHSSRGGSGGRWDRTPSPMLLDLLQSTLNMNPALRPTPVELLQHPFI
                                 |. . |.|. ..  .|  |||  .|||||||
-------------------------------WISQECKDFLRKCFQIDPKKRPTANQLLQHPFI
Kinase LmjF33.1400.AA Pkinase_Tyr 806-904 30 1.3e-18 63.63 Pfam 51-156 (270) Show / Hide 
Range on Protein: 806-904
Range on HMM: 51-156/270
Sequence Identity: 30% (32 aa)

LREIIFLTTL-QHRRIVRFLGFQFSGEGR--LCLLMEYVAGGTLQTLVKN----FGVFEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSSV
.||.  ...| .|  |||..|   . ..   ... |||...| | .  ..     . .    .  . .|| .|.||| .|. .| ||   |.||.|.  |
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KLTDFG
| .|||
KICDFG
Kinase LmjF33.1400.AA Ciliate-E2 1031-1180 14 3e-18 59.24 In-house 247-365 (365) Show / Hide 
Range on Protein: 1031-1180
Range on HMM: 247-365/365
Sequence Identity: 14% (27 aa)

LCGTPLYMSPELIRTQE---------PTFASDMWALGCVVYEMATGGVLPWRPVHNLSAPAVIWYIGQRGEEGDGPSMDDVYTERDRLNRASTDPSLHES
.|||| ||.|| .. ..          ....|.|.||.. ||| .|  .|.                                                 
ICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG-KPPF-------------------------------------------------

VDDSYDEGGGRRGHSSRGGSGGRWDRT--------------------------PSPMLLDLLQS----TLNMNPALRPT-PVELLQHPFI
                      .                               |.   ||..      |. .|  |.| . ..|.||..
---------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF33.1400.AA TKL 1032-1178 15 1.3e-13 45.36 In-house 234-364 (364) Show / Hide 
Range on Protein: 1032-1178
Range on HMM: 234-364/364
Sequence Identity: 15% (27 aa)

CGTPLYMSPELIRTQ----------------EPTFASDMWALGCVVYEMATGGVLPWRPVHNLSAPAVI------WYIGQRGEEGDGPSMDDVYTERDRL
|||| .|.||..| |                | . ..|... | | .|..|. .    | ...  . .|      ... .....|  | ....  .    
CGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN----

NRASTDPSLHESVDDSYDEGGGRRGHSSRGGSGGRWDRTPS-PMLLDLLQSTLNMNPALRPTPVELLQHP
                            ..   . .. ..  | . .|.|   ...|  ||.  |.|.. 
----------------------------HH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF33.1400.AA STE11 1033-1067 47 3.8e-12 40.5 In-house 197-234 (303) Show / Hide 
Range on Protein: 1033-1067
Range on HMM: 197-234/303
Sequence Identity: 47% (18 aa)

GTPLYMSPELIRTQE---PTFASDMWALGCVVYEMATG
||| .|.|| |. .     . ..| |.|||.|.|||||
GTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATG
Kinase LmjF33.1400.AA STE20 1150-1180 45 3e-10 33.95 In-house 258-288 (288) Show / Hide 
Range on Protein: 1150-1180
Range on HMM: 258-288/288
Sequence Identity: 45% (14 aa)

SPMLLDLLQSTLNMNPALRPTPVELLQHPFI
|| . |.. . |...|. |||. .||.||||
SPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF33.1400.AA CMGC 1150-1180 38 3.8e-10 28.59 In-house 483-513 (513) Show / Hide 
Range on Protein: 1150-1180
Range on HMM: 483-513/513
Sequence Identity: 38% (12 aa)

SPMLLDLLQSTLNMNPALRPTPVELLQHPFI
.| ..|||.  | ..|. |.|. . ||||..
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF33.1400.AA TyrKc 615-1180 9 4e-10 -59.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 615-1180
Range on HMM: 1-280/280
Sequence Identity: 9% (57 aa)

LQWGGRIGFGASGDVFMGIDVSTATVVAIKVLKGSSLFQSSQPADTAVAKAHSKTTSGRPAVPSVQDDGTILNLSNISLGNGAVADPRAASEGWTCASHA
.. |  .| || | |. |.     . ||.|.|| ..                                                                
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------------------------------------------------------------

LASPMTLSSHCATSLQVNHANEESIQISEASTPLTPASAVTSSSASAHGNTSAALVNMSSTPHCHTQVQQQQPPRPQSQDEHSASPLLRKHLREIIFLTT
                                                                                       ..  .||.  .. 
---------------------------------------------------------------------------------------REDFMREARIMCK

L--QHRRIVRFLGFQFSGE------GRLCLLMEYVAGGTLQTLVKNFGV-FEENVIRLYTLQILEGLEYLKRKGVVHGDLKSANILVSEQSSVKLTDFGT
|  .|  |||..|   ...      . |...|||...| |.   .. .  .       . .|| .| ||| .|...| ||   |.||.|.  || .||| 
LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL

SRFLRVC-----AAEEKGA-----GE----------------------------------AAGADDERPG-----AEVRRARRRGESREIRHAPAD----
||..        . . . .     |                                       .   ||      . ...... .... .  |..    
SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPM

RAHKRYHHASSPGADAAVEEDSRGEDIGVGNAEGCGDCCRGGSDEDAYSDDIHSAEGTFEEDEEREDLNEDVGPERRLLCGTPLYMSPELIRTQEPTFAS
                                                                                                    
S---------------------------------------------------------------------------------------------------

DMWALGCVVYEMATGGVLPWRPVHNLSAPAVIWYIGQRGEEGDGPSMDDVYTERDRLNRASTDPSLHESVDDSYDEGGGRRGHSSRGGSGGRWDRTPSPM
                                                                                        .      . .. 
----------------------------------------------------------------------------------------F-----VCCPDE

LLDLLQSTLNMNPALRPTPVELLQHPFI
. .. ..  . .|. |||  |.  | ..
MYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF33.1400.AA STE 1150-1180 42 6e-10 31.45 In-house 327-359 (359) Show / Hide 
Range on Protein: 1150-1180
Range on HMM: 327-359/359
Sequence Identity: 42% (14 aa)

SPMLLDLLQSTLNMNPALRPTPVELLQ--HPFI
|| . | ..  |...|  |||. .||.  ||||
SPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF33.1400.AA CAMK 1143-1180 18 1.2e-07 19.92 In-house 362-425 (425) Show / Hide 
Range on Protein: 1143-1180
Range on HMM: 362-425/425
Sequence Identity: 18% (12 aa)

GRWDRTPSPM--------------------------LLDLLQSTLNMNPALRPTPVELLQHPFI
|..|  |...                            ||... |. .|  |.|  . |.||..
GKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF33.1400.AA Ciliate-E2-Unclassified 1152-1180 41 2e-07 21.88 In-house 324-352 (352) Show / Hide 
Range on Protein: 1152-1180
Range on HMM: 324-352/352
Sequence Identity: 41% (12 aa)

MLLDLLQSTLNMNPALRPTPVELLQHPFI
.. ||||. |. ||  |.|. ..|.||..
FINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF33.1400.AA STE20 1031-1067 35 8.3e-07 21.24 In-house 182-223 (288) Show / Hide 
Range on Protein: 1031-1067
Range on HMM: 182-223/288
Sequence Identity: 35% (15 aa)

LCGTPLYMSPELIRT-----QEPTFASDMWALGCVVYEMATG
..||| .|.||.|.      .. .. .| |.||    |||.|
FVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEG
Kinase LmjF33.1400.AA CMGC 1037-1068 28 2e-06 16.31 In-house 291-339 (513) Show / Hide 
Range on Protein: 1037-1068
Range on HMM: 291-339/513
Sequence Identity: 28% (14 aa)

YMSPELIRTQE----------PTFASDMWALGCVVYEMATG-------G
| .||..   .           | . |||..||. .|| ||       |
YRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRG
Kinase LmjF33.1400.AA STE11 1150-1180 45 2e-06 20.01 In-house 273-303 (303) Show / Hide 
Range on Protein: 1150-1180
Range on HMM: 273-303/303
Sequence Identity: 45% (14 aa)

SPMLLDLLQSTLNMNPALRPTPVELLQHPFI
|. . | |. ..  .|  |||  .|||||||
SEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Pkinase LmjF33.1400.AA Pkinase 615-647 33 2.6e-05 19.86 Pfam 1-33 (293) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-33/293
Sequence Identity: 33% (11 aa)

LQWGGRIGFGASGDVFMGIDVSTATVVAIKVLK
.. |..|| |..| |. .....|  .||.|..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK
Kinase LmjF33.1400.AA Pkinase_Tyr 1038-1072 36 3e-05 18.38 Pfam 181-216 (270) Show / Hide 
Range on Protein: 1038-1072
Range on HMM: 181-216/270
Sequence Identity: 36% (13 aa)

MSPELIRTQEPTFASDMWALGCVVYEMATGGVLP-W
|.|| |.. . | .|| |. | . .|. | |  | .
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase LmjF33.1400.AA Dicty2 1033-1067 43 3.8e-05 14.04 In-house 169-205 (264) Show / Hide 
Range on Protein: 1033-1067
Range on HMM: 169-205/264
Sequence Identity: 43% (16 aa)

GTPLYMSPELIRTQE--PTFASDMWALGCVVYEMATG
|||  | || |  .    . |.| | ||| . |. ||
GTPYWMAPEVIQMSGNHCCTACDIWSLGCTIIELLTG
Kinase LmjF33.1400.AA STE20 615-647 27 0.00014 13.0 In-house 1-37 (288) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-37/288
Sequence Identity: 27% (10 aa)

LQWGGRIGFGASGDVFMGIDVSTATV----VAIKVLK
 .   .|| |..|.|. .....|  .    ||||...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMN
Kinase LmjF33.1400.AA CAMK 620-647 25 0.000283 8.89 In-house 1-40 (425) Show / Hide 
Range on Protein: 620-647
Range on HMM: 1-40/425
Sequence Identity: 25% (10 aa)

RIGFGASGDVFMGIDVSTA------------TVVAIKVLK
 .| |. | |. .|. .|             . ||||...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIID
Kinase LmjF33.1400.AA STE 615-647 22 0.000343 10.84 In-house 1-48 (359) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-48/359
Sequence Identity: 22% (11 aa)

LQWGGRIGFGASGDVFMGIDV------STATV---------VAIKVLK
..  ..|| ||.| |. ....      .|  |         .|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMN
Kinase LmjF33.1400.AA Dicty2 1150-1180 38 0.000399 10.45 In-house 234-264 (264) Show / Hide 
Range on Protein: 1150-1180
Range on HMM: 234-264/264
Sequence Identity: 38% (12 aa)

SPMLLDLLQSTLNMNPALRPTPVELLQHPFI
|| ..| |.   .  | .|.|  .||.|| |
SPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase LmjF33.1400.AA Dicty2 616-644 46 0.012618 5.16 In-house 2-31 (264) Show / Hide 
Range on Protein: 616-644
Range on HMM: 2-31/264
Sequence Identity: 46% (14 aa)

QWG-GRIGFGASGDVFMGIDVSTATVVAIK
| |   || ||.| |. | .  |  .||||
QIGDEKIGKGAFGTVYKGLHIETGDFVAIK
Kinase LmjF33.1400.AA CMGC 615-647 25 0.014075 3.25 In-house 1-47 (513) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-47/513
Sequence Identity: 25% (12 aa)

LQWGGRIGFGASGDVFMGID--------------VSTATVVAIKVLK
 .  ..|| |. | |. ..|                |  .|||| .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIK
Kinase LmjF33.1400.AA STE11 615-647 36 0.017517 5.14 In-house 1-33 (303) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-33/303
Sequence Identity: 36% (12 aa)

LQWGGRIGFGASGDVFMGIDVSTATVVAIKVLK
 | |  || || | |.....|.| ...|.|  .
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIE
Kinase LmjF33.1400.AA Pkinase_Tyr 615-647 35 0.038357 7.88 Pfam 1-37 (270) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-37/270
Sequence Identity: 35% (13 aa)

LQWGGRIGFGASGDVFMGIDV----STATVVAIKVLK
.. |  .| || |.|..|.      .| . ||.|.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase LmjF33.1400.AA STE11-Unclassified 615-647 30 0.092482 2.09 In-house 1-33 (308) Show / Hide 
Range on Protein: 615-647
Range on HMM: 1-33/308
Sequence Identity: 30% (10 aa)

LQWGGRIGFGASGDVFMGIDVSTATVVAIKVLK
 | |  || |. | |. .....|  ..|.| ..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIE