Gene LmjF33.2290 (L.major)

LmjF33.2290

Species: L.major
Alias: LmajK215, LmjF33.2290
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF33.2290.AA Protein None 1984 None Fasta, JSON
LmjF33.2290.kin_dom Protein Kinase Domain None 502 None Fasta, JSON

Protein domain

Protein domains of LmjF33.2290.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF33.2290.AA S_TKc 1482-1983 13 7.6e-65 222.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 1482-1983
Range on HMM: 1-231/231
Sequence Identity: 13% (72 aa)

RRSYDILGTGAFSTVYRGLSMS-GNLVALKCFQLGARNIEVHAIVDEVRLFANLHHENVVQYLSLYVSGSHVIEIMEFVPG--GSLDTLLKSFGS-----
 .  ...| |||..||..   . | .||.|.            |  |...  . ||.|.|...  ... .|.  .||...|  |.| ...|. |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAIARATSSICSIDSVLEMRGTPGYMAPEVARGEVPTM-KSDVYSLGITI
 . .  .|.||. |...| |.|  .|.|.|.|| |.||    . |..|||.|                . ||| ||||||      .  |.|..|.|...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELLTGRLPWDYADAFAPKLSGKLTQPKSASEQRASQLQTCPAAGARGTRVADGSVAQVGADLSKKTWNAGIAATRGPSGGPMTDSRLDAATMLSNSSYA
 |.|.|. |..      ...  |.                                                                            
YEMLCGYPPFP-----QMQMMFKKIG--------------------------------------------------------------------------

GPATSMGETVCGFGSGLLSSKNQSGEAEHSFRRLEFSGSGAEIAEGNAGLCQHALASTLEERASATVASLRATTASLVKVAAGKNAAAEACDEDGTGMPL
                                                                                                    
----------------------------------------------------------------------------------------------------

GGSLKPSLEINQSRQQHHSIAYIPSSTSRRPSSAIFSSFYQNPRFAVSLHRRPIEQVLRSSTELVVYIGRGLVVPRIPDTLDEDVINFLELCLKPDPAER
                                                                                 ......|.. ||. ||..|
---------------------------------------------------------------------------------SPEAKDFIRKCLQKDPEKR

ASMSELML-------HPWL
 .  |..        |||.
PTA-EALQDEWDIKCHPWF
Kinase LmjF33.2290.AA Pkinase 1482-1682 27 5.8e-56 197.02 Pfam 1-213 (293) Show / Hide 
Range on Protein: 1482-1682
Range on HMM: 1-213/293
Sequence Identity: 27% (61 aa)

RRSYDILGTGAFSTVYRGLSMSGNL-VALKCFQLGARNIEVHAIV---DEVRLFANLHHENVVQYLSLYVSGSHVIEIMEFVPGG----SLDTLLK--SF
 .   ..| |.|..||..   . .  ||.|.. .  .. ... .     |... ..|.|.|.|...  . ...|.  .||...||    .| ....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSL--RPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQC----KLSDFGSAIARATSSICSIDSVLEMRGTPGYMAPEVAR-GEVPTMKSDV
|..   .. ...||. |.||| |.|  .|.|.|.|| |.|.  .|..    |..|||.|       . .        |||.|||||| | |.  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSLGITILELLTGRLPWD
.|.|... |.|.||.|..
WSCGCILYEMLCGRPPFP
Kinase LmjF33.2290.AA STE 1482-1681 27 2e-51 177.18 In-house 1-268 (359) Show / Hide 
Range on Protein: 1482-1681
Range on HMM: 1-268/359
Sequence Identity: 27% (74 aa)

RRSYDILGTGAFSTVYRGLSM----------------SGNLVALKCFQLGA-------------RNI---EVHAIVDEVRLFANLH--HENVVQYLSLYV
 .  ...| ||| |||... .                .|...| |   |               .|.   |.  |  |...  ...  |.|.|.|.  |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SG-------SHVIEIMEFVPGGSLDTLLK-SFGSLRP------------ESVR-RYMRDIARG-LSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAI
 .       ...  .||...||||| ..|  .| ..|            ||.  .. |.| .| |.|||  .|.| |||| |.||     .||.||| . 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ARATSSI-----------CSIDSVL-EMRGTPGYMAPEVARGEVPT------MKSDVYSLGITILELLTGRLPW
  . |.             ....    . ||| .||||| ...  .       |.|..|||.||.|..||. ||
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase LmjF33.2290.AA TKL 1488-1682 22 2.9e-49 169.97 In-house 1-290 (364) Show / Hide 
Range on Protein: 1488-1682
Range on HMM: 1-290/364
Sequence Identity: 22% (68 aa)

LGTGAFSTVYRGLSMS---------GNLVALKCFQLGARNI--------------------------EVHAIVDEVRLFANLHHENVVQYLSLYVSGSH-
.| |.|..||.|  .          |. || | |     .                           .   .. |...  .|.|.|.||..    .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VIEIMEFVPGGS-LDTLLKSFGSLRPESVRRYMRDIARGLSYLHTAN--------IVHCDIKPHNVLLAMDGQ--------------C
               .||..|||| |..|.       ..   | ..|||||..|||. |        |.|.|.|..|.|.  ...              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLSDFGSA--IARATSSICSIDSVLE-------------MRGTPGYMAPEVARGE----------------VPTMKSDVYSLGITILELLTGRLPWD
|..||| .  . . ... ..  .. |              .|||..||||| ||.                  . |.|||| || . |.||...|..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase LmjF33.2290.AA STE11 1482-1681 34 3.7e-45 156.35 In-house 1-238 (303) Show / Hide 
Range on Protein: 1482-1681
Range on HMM: 1-238/303
Sequence Identity: 34% (81 aa)

RRSYDILGTGAFSTVYRGLSMS-GNLVALKCFQLGARNI-------EVHA------IVDEVRLFANLHHENVVQYLSLYV---SGSHVIEIMEFVPGGSL
 .. .|.|.|||.|||... .. | |.| |  ...  |        |. .      | .|..|. .|.|.| |.|.   .   . .||  .||..|||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

DTLLK-SFGS--LRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQ-CKLSDFGSAIARATSSICSIDSVLE------MRGTPG--------
  .|.  .|   .    .|.| ..| .||.|||  .|.| |||. |.||  ||. |||.|||.|   |..  |.  .         |.|||         
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YMAPEVARGEV---PTMKSDVYSLGITILELLTGRLPW
.||||| ..|     . |.|. ||| |..| .||. ||
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPW
Kinase LmjF33.2290.AA MEKK15 1481-1688 37 4.4e-44 152.77 In-house 1-214 (264) Show / Hide 
Range on Protein: 1481-1688
Range on HMM: 1-214/264
Sequence Identity: 37% (81 aa)

WRRSYDILGTGAFSTVYRGLSMSGNLVALKCFQLGARN-----IEVHAIVDEVRLFANLHHENVVQYLSLYVSGSHVIEIMEFVPGGSLDTLLKSFGSLR
|..  .||| ||. ||| ||   | |.| |  .|   .      .   . .|| |   |.| |.| ||   .    |   |.||||||.  ..  ||.| 
WKKG-NILGKGAYGTVYCGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLD

PESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAIARATSSICSID-SVLE-MRGTPGYMAPEVARGEVPTMKSDVYSLGITILE
     .| . | .|  |||  ..|| |||  ||.|   |  || ||| |   .   |      .|  ||||| .|||||        |||..|.| |. |
EMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVFE

LLTGRLPWDYADAFA
. |.. ||   |  |
MATRKPPWADMDRMA
Kinase LmjF33.2290.AA Ciliate-E2-Unclassified 1483-1983 11 9.5e-41 139.07 In-house 2-352 (352) Show / Hide 
Range on Protein: 1483-1983
Range on HMM: 2-352/352
Sequence Identity: 11% (71 aa)

RSYDILGTGAFSTVYRGLSMSGN--------LVALKCFQLGARN----------IEVHAIVDEVR--------LFANLHHENVVQYLSLYVSGSHVIEIM
.   ..|.|.|..||.    . .         .. .. |.  .|          .. .   . .|        .. |. |...| ..    .  ... .|
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFVPGGSLDTLLKSFGS-----------------LRPESVR-----RYMRDIARGLSYLHTAN-IVHCDIKPHNVLLAMDG---QCKLSDFGSAIARATS
|...||.|   .|....                 .  . ..     .|.. |  ||.|||  | |.| |||| |.|.  .|   ..|..|||...   ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

SIC-----------SIDSVLEMRGTPGYM----APEVARGEVPT----MKSDVYSLGITILELLTGRLPWDYAD-------------------AFAPKLS
. |           . .    . |||.||    |||| .|. .      |.|..|||. . |.|.|..| .. .                    .  .. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GKLTQPKSASEQRASQLQTCPAAGARGTRVADGSVAQVGADLSKKTWNAGIAATRGPSGGPMTDSRLDAATMLSNSSYAGPATSMGETVCGFGSGLLSSK
... .||.   |                                                                                        
KNIQFPKFPWQQ----------------------------------------------------------------------------------------

NQSGEAEHSFRRLEFSGSGAEIAEGNAGLCQHALASTLEERASATVASLRATTASLVKVAAGKNAAAEACDEDGTGMPLGGSLKPSLEINQSRQQHHSIA
                                                                                                    
----------------------------------------------------------------------------------------------------

YIPSSTSRRPSSAIFSSFYQNPRFAVSLHRRPIEQVLRSSTELVVYIGRGLVVPRIPDTLDEDVINFLE----LCLKPDPAERASMSELMLHPWL
                                                       ||..... ...|..     .|| .| .| ...... |||.
-------------------------------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF33.2290.AA CAMK 1487-1682 17 7.3e-40 125.64 In-house 1-335 (425) Show / Hide 
Range on Protein: 1487-1682
Range on HMM: 1-335/425
Sequence Identity: 17% (59 aa)

ILGTGAFSTVYRGLSM-SG------------NLVALKCFQL-GARNIE--------------------------VHAIVDEVRLFAN-------LHHENV
.||.|.|..|...    ..              || |      ... .                           . .  |...  .       |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYLSLYV------------SGSH--------VIEIM---EFVPGG----SLDTLLKSFGS---------------LRPESVRRYMRDIARGLSYLHTAN
.. .  |             . |.        .. .|   |...||     |   ... |.               .  . .|||.| |. .. |.|  |
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHCDIKPHNVLLAMD-----------------GQCKLSDFGSAIARATSSICSID-------------------SVLEMRGTPGYMA-PEVARG-----
|||.|.|| |.||  .                 .. |..||| |.    .. .  .                      .. |||.||| ||| .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EVP-TMKSDVYSLGITILELLTGRLPWD
        . . . |.|. |.|.    .|.|..|..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY
Kinase LmjF33.2290.AA STE11-Unclassified 1483-1681 31 3.6e-39 136.45 In-house 2-238 (308) Show / Hide 
Range on Protein: 1483-1681
Range on HMM: 2-238/308
Sequence Identity: 31% (74 aa)

RSYDILGTGAFSTVYRGLSMS-GNLVALKCFQLGARNI-------E-VHAIVDEVRLFANLHHENVVQYLSLY--VSGSHVIEIMEFVPGGSLDTLLKSF
 . ...|.|.| .|| ..  . | ..| |    .  |.       | . .| .|...  .|.|.| |||.     ......  .|| .||||.. .|. .
QKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNKY

GSLRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAIARATS----------------SIC-SIDS----VLEMRGTPG---Y
| .  .  . | ..|  ||.|||  .|.| |||. |.|.  || |||.|||.|  .. .                .|| .|.|      .|.|||    .
GCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFW

MAPEVAR---GEVPTMKSDVYSLGITILELLTGRLPW
||||| .    .  . |||. ||| |..|  ||. ||
MAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPW
Kinase LmjF33.2290.AA MEKK2 1481-1699 39 5.8e-38 132.43 In-house 1-226 (262) Show / Hide 
Range on Protein: 1481-1699
Range on HMM: 1-226/262
Sequence Identity: 39% (89 aa)

WRRSYDILGTGAFSTVYRGLSM-SGNLVALKCFQLGARNI----EVHAIVDEVRLFANLHHENVVQYL-SLYVSGSHVIEI-MEFVPGGSLDTLLKSFGS
|||   .|| |||  ||    .  |  .| |  |    |     ||.|.  |..|  || || .|||   |   . ... | ||..||||.   || .|.
WRRG-KLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGA

LRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAIARATSSICSIDSVLEMRGTPGYMAPEVARGEVPTMKSDVYSLGITILE
|  .  |.| | |  |..|||   ||| |||  |.|    |  ||.||| |  |      .|  .  . ||| .|.|||  ||    | ||.|.| |. |
LTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFG-ASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVE

LLTGRLPWDYADAFAP--KLSGKLTQPK
.|| . ||   .| |   |.  . |.|.
MLTEKPPWAEYEAMAAIFKIATQPTNPQ
Kinase LmjF33.2290.AA ULK 1482-1685 22 2.1e-35 121.07 In-house 1-262 (329) Show / Hide 
Range on Protein: 1482-1685
Range on HMM: 1-262/329
Sequence Identity: 22% (58 aa)

RRSYDILGTGAFSTVYRGLSMSGN---LVALKCFQLG---ARNIEVH--------AIVDEVRLFANLH--------HENVVQYLSLYVSG--SHVIEIME
    ..|| |.| .||.|  .  .    .. .| ..     ....           .  |...   |.        |.|.|...  . .    ..  |||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FVPGGSLDTLLKSFGS----------LRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMD------------GQCKLSDFGSAIARATS--SIC
. .|| |....|  .           |  . .. ....|. |. .||  ||.|.|||| |.|.  .            |..|..||| |     .  .. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

SIDSVL---EMRGTPGYMAPEVAR----GEVPT-MKSDVYSLGITILELLTGRLP---WDYAD
 . . .     .||| ||||..      .. ..  |.|..|||. . |.|.|. |   | . |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FND
Kinase LmjF33.2290.AA STE-Unique 1555-1681 24 5.6e-32 110.57 In-house 372-553 (616) Show / Hide 
Range on Protein: 1555-1681
Range on HMM: 372-553/616
Sequence Identity: 24% (44 aa)

IMEFVPGGSLDTLLKSFGS---------LRPESVRRYMRDIARGLSYLHTAN--IVHCDIKPHNVLLAMDG-----QCKLSDFGSAIARATSSI------
.||. ..|.|....|. |          .. . | .| . |. || |||.    |.| |.||||.... ||       |..||| |.  .  .       
FMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNS

----------------------------CSIDSVLEMRGTPGYMAPEVARGE-----VPTMKSDVYSLGITILELLTGRLPW
                             .. .   ..|||.||.||| ...         |.|..|||........|  ||
KNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPW
Kinase LmjF33.2290.AA Pkinase_Tyr 1488-1622 27 6.1e-23 78.31 Pfam 7-156 (270) Show / Hide 
Range on Protein: 1488-1622
Range on HMM: 7-156/270
Sequence Identity: 27% (41 aa)

LGTGAFSTVYRGLSM-----SGNLVALKCFQLGARNIE--VHAIVDEVRLFANL-HHENVVQYLSLYV-SGSH--VIEIMEFVPGGSLDTLLKS----FG
|| ||| .||.|         .  || |.   ||   .    .   |...  .| ||.|.|...   .  | .  .. .||..|.|.|.. |..     .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

SLRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFG
.| ..    . ..||.|..||.  |..| |.   |.|.. ....| .|||
PLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase LmjF33.2290.AA TyrKc 1482-1983 13 3.8e-16 38.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 1482-1983
Range on HMM: 1-280/280
Sequence Identity: 13% (70 aa)

RRSYDILGTGAFSTVYRGLSMSGNLVALKCFQLGARNIEVHAIVDEVRLFANL--HHENVVQYLSLYVSG-------SHVIEIMEFVPGGSLDTLLKSFG
 .  ..|| ||| .||.|       || |. . .|    . .. .| |.  .|  ||.|.|. .   ...         .  .||..|.|.|.  |.. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-LRPESVRRYMRDIARGLSYLHTANIVHCDIKPHNVLLAMDGQCKLSDFGSAIARATSSI------CSIDSVLEMRGTPG-----YMAPEVARGEVPTM
  | ..    .. .||.| .|||  |..| |.   |.|.. ....| ||||   .|.  .        .  .. | .|. .      ||||. .  . | 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFG--LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSLGITILELLT-GRLPWDY--------ADAFAPKLSG-KLTQPKS----ASEQRASQLQTCPAAGARGTRVADGSVAQVGADLSKKTWNAGIAAT
||||.| |... |..| |  |.          .....   .|  . ||..    .                                             
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------------------------

RGPSGGPMTDSRLDAATMLSNSSYAGPATSMGETVCGFGSGLLSSKNQSGEAEHSFRRLEFSGSGAEIAEGNAGLCQHALASTLEERASATVASLRATTA
                                                                                                    
----------------------------------------------------------------------------------------------------

SLVKVAAGKNAAAEACDEDGTGMPLGGSLKPSLEINQSRQQHHSIAYIPSSTSRRPSSAIFSSFYQNPRFAVSLHRRPIEQVLRSSTELVVYIGRGLVVP
                                                                                                    
----------------------------------------------------------------------------------------------------

RIPDTLDEDVINFLELCLKPDPAERASMSELMLHPWL
    .  ... .  . | . ||..| ..||.  |  .
-F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF33.2290.AA STE 1946-1983 23 1.2e-12 41.14 In-house 301-359 (359) Show / Hide 
Range on Protein: 1946-1983
Range on HMM: 301-359/359
Sequence Identity: 23% (14 aa)

PRIPDTLD-------------------EDVINFLELCLKPDPAERASMSELML--HPWL
|..||.|.                   .. ..|...||. || .|.. |.|.   ||..
PPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF33.2290.AA CAMK 1949-1983 20 2e-10 29.04 In-house 392-425 (425) Show / Hide 
Range on Protein: 1949-1983
Range on HMM: 392-425/425
Sequence Identity: 20% (7 aa)

PDTLDEDVINFLELCLKPDPAERASMSELMLHPWL
. ..........  .|..|| .|.. .. . |||.
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF33.2290.AA STE11 1938-1983 30 3.3e-10 33.41 In-house 251-303 (303) Show / Hide 
Range on Protein: 1938-1983
Range on HMM: 251-303/303
Sequence Identity: 30% (16 aa)

YIGRG-LVVPRIPDTLD------EDVINFLELCLKPDPAERASMSELMLHPWL
.||.|    | ||. .       |.  .|| .|...|| .|.. ..|  ||..
KIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase LmjF33.2290.AA MEKK15 1936-1983 34 2.4e-09 30.04 In-house 216-264 (264) Show / Hide 
Range on Protein: 1936-1983
Range on HMM: 216-264/264
Sequence Identity: 34% (17 aa)

VVYIGRG-LVVPRIPDTLDEDVINFLELCLKPDPAERASMSELMLHPWL
. ||| .  ..|..|.   ||  .| ..||  |  ||.. |.|. ||..
MFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase LmjF33.2290.AA STE11-Unclassified 1946-1983 26 6e-09 27.92 In-house 260-308 (308) Show / Hide 
Range on Protein: 1946-1983
Range on HMM: 260-308/308
Sequence Identity: 26% (13 aa)

PRIPDTLD-----------EDVINFLELCLKPDPAERASMSELMLHPWL
| || .|            ..  .||..|.. || .|.. ..|  ||..
PQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQLLQHPFI
Kinase LmjF33.2290.AA STE-Unique 1948-1983 36 9.9e-08 22.93 In-house 581-616 (616) Show / Hide 
Range on Protein: 1948-1983
Range on HMM: 581-616/616
Sequence Identity: 36% (13 aa)

IPDTLDEDVINFLELCLKPDPAERASMSELMLHPWL
||. .  . . |.|.||...|  |.| ..|  |.||
IPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase LmjF33.2290.AA ULK 1946-1983 23 1e-06 19.49 In-house 287-329 (329) Show / Hide 
Range on Protein: 1946-1983
Range on HMM: 287-329/329
Sequence Identity: 23% (10 aa)

PRIP-----DTLDEDVINFLELCLKPDPAERASMSELMLHPWL
...|     ... .......  .|. |. .| |  ||  |||.
LQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase LmjF33.2290.AA Pkinase 1952-1983 31 1e-06 24.32 Pfam 262-293 (293) Show / Hide 
Range on Protein: 1952-1983
Range on HMM: 262-293/293
Sequence Identity: 31% (10 aa)

LDEDVINFLELCLKPDPAERASMSELMLHPWL
..|. . |.. ||..||..| .  ... |||.
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF33.2290.AA STE-Unique 1483-1550 22 3e-06 17.81 In-house 1-74 (616) Show / Hide 
Range on Protein: 1483-1550
Range on HMM: 1-74/616
Sequence Identity: 22% (17 aa)

RSYDILGTGAFSTVYRGL-SMSGNLVALKCFQLGARNIE-----VHAIVDEVRLFANLHHENVVQYLSLYVSGS
.  ...|.|.| .|..      .. .| |   |  . ..     |  |. |. . . |||.|.| |.  . .|.
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG
Kinase LmjF33.2290.AA MEKK2 1946-1983 26 0.000713 9.92 In-house 225-262 (262) Show / Hide 
Range on Protein: 1946-1983
Range on HMM: 225-262/262
Sequence Identity: 26% (10 aa)

PRIPDTLDEDVINFLELCLKPDPAERASMSELMLHPWL
|..|. . ..  .||..| .   ..| |  ||. | . 
PQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase LmjF33.2290.AA Pkinase_Tyr 1648-1681 41 0.001498 12.65 Pfam 181-216 (270) Show / Hide 
Range on Protein: 1648-1681
Range on HMM: 181-216/270
Sequence Identity: 41% (15 aa)

MAPEVARGEVPTMKSDVYSLGITILELLT-GRLP-W
||||. .  . | ||||.| |... |..| |. | .
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTY
Kinase LmjF33.2290.AA TKL 1946-1981 18 0.003758 7.21 In-house 317-364 (364) Show / Hide 
Range on Protein: 1946-1981
Range on HMM: 317-364/364
Sequence Identity: 18% (9 aa)

PRIP------------DTLDEDVINFLELCLKPDPAERASMSELMLHP
| ||            .. ...... .. | ..|| .| |..|.. . 
PPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL