Gene LmjF34.2090 (L.major)

LmjF34.2090

Species: L.major
Alias: LmjF34.2090, LmajK220
External Links:
Annotation:

Classification

Group: STE
Family: STE7
Subfamily: MEK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF34.2090.AA Protein None 385 None Fasta, JSON
LmjF34.2090.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of LmjF34.2090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF34.2090.AA S_TKc 58-326 26 6.7e-63 216.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-231/231
Sequence Identity: 26% (75 aa)

LKRVRQLGQGTQGNVSMYVTAD-KSVFAVKKITIPVTLDTRTRQTVAAELRNIFSAQSNEYTVNLYNAFYRNRALRLVMEYMDW--GNIDELIAEKVK--
 . .|..|.|. | |   .  . . ..|.|.|           ...  |..   .    .. |.|| .|.    | .||||.|   |.  ..| .. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----IPPTVCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAETIGVNSFVGTATYMSPERIQGRRYST-P
    .|. .. ... |.. ||. .| . .|            ||||.||.|.||..  ..|..|||.|.       ..|.||  ||.|| .    |.. .
LRFPFPE-HARFYMYQICCALEYCHSH-GI------------IHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCK

SDIWSVGVVVAQMLLGHYPFSSVGKGFMALLREINSVEKYPLMEETGCSQEAQDFIDSCLRQDPDDRSSAFELLE-------SPWI
.|.||.|.... || |  ||.      ..... |              |.|| |||. ||. ||..| .| |.|.        ||.
CDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF34.2090.AA STE 58-326 22 8.4e-60 204.99 In-house 1-359 (359) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-359/359
Sequence Identity: 22% (86 aa)

LKRVRQLGQGTQGNVSMYVTADKS----------------VFAVKKITIPVTL--------------DTRTRQTVAAELRNIFSAQS-NEYTVNLYNAFY
.......|.|. | |   .  ...                ..|.|.. .                  ..  .| .  |..     ..  .. |. | ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RNR-------ALRLVMEYMDWGNIDELIAEKVKIPP--------------TVCGYIASQMLHA-LAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLST
..         | ..||||| | .|..| .| ...               .. .||. | |.. |. ||             |.. |||||||||.||  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH-------------SHHIIHRDIKPANILL--

TGCVKLADFGIATSAETI------------------GVNSFVGTATYMSPERIQGRR------YSTPSDIWSVGVVVAQMLLGHYPF---SSVGKGFMAL
   |||.|||.... . .                    |.||||  .|.||.||...      |.| .||||.| ..  |. |..|.   .     ||..
---VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIP

-----------LREINSVEKYPLME-----------------ETGCSQEAQDFIDSCLRQDPDDRSSAFELLE--SPWI
           |  |.  .  || .                  . .|.| .|||. ||. ||..| .| .||.   |.|
FNYHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Pkinase LmjF34.2090.AA Pkinase 58-326 24 1.6e-58 205.53 Pfam 1-293 (293) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

LKRVRQLGQGTQGNVSMYVTADKSV---FAVKKITIPVTLDTRTRQTVA-AELRNIFSAQSNEYTVNLYNAFYRNRALRLVMEYMDWG----NIDELIA-
....|..|.|. | |  |   .|.    .|||.|  . . .   .. .  .|..   .  . .. | || .|.... . .||||.. |       ..|  
YHIGRKIGSGSFGCV--YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-EKVKI--PPTVCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCV----KLADFGIAT---SAETIGVNSFVGTATYMSPER
 .. ..  .. .|  .. |.| .|. .| .             . ||||.||.|.|.. .| .    |..|||.|           ..|.||  ||.|| 
WRHGCFYFSEWECKFYMYQILRGLEYCHSM-------------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV

IQ-GRRYSTPSDIWSVGVVVAQMLLGHYPFSSVGK----GFMALLREINSVEK--YPLMEETGCS-------------------QEAQDFIDSCLRQDPD
|. |. |....|.||.|.....||.|. ||.  |.    . .  .  |. . .  ..  ... ||                   .|..|||..||..|| 
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFP--GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

DRSSAFELLESPWI
.| .| ..|..||.
KRPTAEQILQHPWF
Kinase LmjF34.2090.AA STE7 58-326 28 2.8e-55 189.94 In-house 1-288 (288) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-288/288
Sequence Identity: 28% (88 aa)

LKRVRQLGQGTQGNVSM-YVTADKSVFAVKKITIPVTLDT-RTRQTVAAELRNIFSAQSNEYTVNLYNAFYRNRA--LRLVMEYMDWGNID---ELIAEK
|... .|| |  |.| . .   .  ..|||  .|..|..  . ..    ||  ... .  .|.|  | |||..      ..||||| | .|   ... ..
LEHIGELGHGNYGVVYKMRHKPSGKIMAVK--RIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKV

------VKIPPTVCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAE-TI-GVNSFVGTATYMSPERIQG-
       .||  . |.|| . ...|  ||.| .|            ||||.|| |.|. . |.|||.||||.   . ..   ..|||...||.||||.| 
YRGIKKGRIPEQILGKIAVAVIKGLHYLHEKHKI------------IHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGN

-RRYSTPSDIWSVGVVV-AQMLLGHYPFSSVGK----------------GFMALLREINSVEKYPLMEETGCSQEAQDFIDSCLRQDPDDRSSAFELLE-
   |.  ||.||.|.    .| .| ||. .                   ... .|..|    ..|  .  . | | |||.. ||. ||..| . ..|.. 
KQHYDVRSDVWSLGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP--KFSPEFQDFVNKCLQKDPNERPKYHQLMKE

SPWI
 |.|
HPFI
Kinase LmjF34.2090.AA STE7-Unclassified 185-326 34 5.4e-44 152.48 In-house 136-301 (301) Show / Hide 
Range on Protein: 185-326
Range on HMM: 136-301/301
Sequence Identity: 34% (57 aa)

HKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAETIG--VNSFVGTATYMSPERIQGR-----RYSTPSDIWSVGVVVAQMLLGHYPFS---------
|... .||||||| |.|..  | ||..|||..  .|     ....||. .|||||||||.      ||  |||||.| .   . .| ||..         
HEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPHRPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYN

-SVGK---GFMALLREINSVEKYPLMEET---GCSQEAQDFIDSCLRQDPDDRSSAFELLE-SPWI
 ..     .|  ||  |.  .  .| ...     | |..|||. |.  .| .|.....||.  |||
QNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHPWI
Kinase LmjF34.2090.AA STE20 58-326 26 1.4e-41 144.51 In-house 1-288 (288) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-288/288
Sequence Identity: 26% (81 aa)

LKRVRQLGQGTQGNVSMYVTADK---SV----FAVKKITIPVTLDT-RTRQTVAAELRNIFSAQSNEYTVNLYNAFYRN----RALRLVMEYMDWGNIDE
 . ....|||. | |  |.  .|    .     |.||. .    .    ....  | .     . ... |. |......      | .||||.. | . .
YELLEKIGQGSYGKV--YKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD

LIAEKVKIPP---------TVCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAET-----IG-V-NSFVG
.. ...|.               ||  ..| .|. ||             | ..|||||| .|.||.. | ||||||| . . ..     ..   |.|||
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLH-------------SNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVG

TATYMSPERIQG-----RRYSTPSDIWSVGVVVAQMLLGHYPFSSVGKGFMALLREIN--SVEKYPLME--ETGCSQEAQDFIDSCLRQDPDDRSSAFEL
|  .|.|| ||.       | . .||||.|     |. |. |.. .    |  . .|   . .. .|..   . .|.| .||.|.|| .||..| .| .|
TPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHP--MRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQL

LESPWI
|. |.|
LKHPFI
Kinase LmjF34.2090.AA CAMK 63-326 17 8.9e-40 125.37 In-house 1-425 (425) Show / Hide 
Range on Protein: 63-326
Range on HMM: 1-425/425
Sequence Identity: 17% (75 aa)

QLGQGTQGNVSMYVTA-DK------------SVFAVKKITIPVTLD-------------------------TRTRQTVAAELRNIFSAQ------SNEYT
.||.|. | |   .   ..              .|.| |      |                          ..|. |  |..   . |      . .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLYNAFY------------RNRA--------LRLVM---EYMDWG----NIDELIAEK---------------VKIPPTVCGYIASQMLHALAVLHTKS
..|| ..               .         . .||   ||.. |     . . | |.                ...   . ..  |.. |.. .| . 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

NIVTEPNQHKSLRQIHRDIKPANVLLSTT-----------------GCVKLADFGIATSAETIG-------------------------VNSFVGTATYM
 ||            |||.|| |.||..                  . .|..||| |.  .                             . |.||  ||
-IV------------HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

S-PERIQG--------------RRYSTPSDIWSVGVVVAQMLLGHYPFSSV-----------GKGFMALLREINSVE-KYPLME----------------
. || ..|              . |. ..|.||.||.   || |..|| .            |.    |.. | . .  .|  .                
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDI

-----ETGCSQEAQDFIDSCLRQDPDDRSSAFELLESPWI
     .  .|||..|.| ..|. ||..| .. . |. ||.
SDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF34.2090.AA Ciliate-E2 58-326 20 2.7e-38 129.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-365/365
Sequence Identity: 20% (80 aa)

LKRVRQLGQGTQGNVSMY-VTADKSVFAVKKITIPVTLDTRT-------------RQTVAAELRNIFSAQS----------------------NEYTVNL
 | ....|||..| |    |  ..  || |.|.    .  |.              .    ....|.. ..                      . . ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID--QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

YNAFY--RNRALRLVMEYMDWGNIDELIAEK----VKIPP-------TVCGYIASQMLH---------------ALAVLHTKSNIVTEPNQHKSLRQIHR
| .|.   .  . ||||| . |.  ..| ..     ....         ..||  | |                ||  || | ||            |||
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNI------------IHR

DIKPANVLLSTTGCVKLADFGIATSAETI---------------------------------GVNSFVGTATYMSPERIQ---------GRRYSTPSDIW
|||| |.|.     .|..|||... . .                                   .|...||. ||.|| ..         . .|.. .|||
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SVGVVVAQMLLGHYPFSSVGKGFMALLREINS-VEKYPLMEET--------------GCSQEAQDFIDS----CLRQDPDDRSS-AFELLESPWI
|.||.  .|| | .||          ...|     ..|  | .               .|||..|.|      .|  ||. | . . ..|. ||.
SLGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF34.2090.AA MEK1 58-266 33 2.6e-37 124.75 In-house 1-195 (297) Show / Hide 
Range on Protein: 58-266
Range on HMM: 1-195/297
Sequence Identity: 33% (70 aa)

LKRVRQLGQGTQGNVSMYVTADKSVFAVKKITIPVTLDTRTRQTVAAELRNIFSAQSNEYTVNLYNAFYRNRALRLVMEYMDWGNIDELIAEKVKIPPTV
....  ||.|  | | | .   ..   . .  | . .    |. .  ||. .    |  | |  | ||| .  . . ||||| | .| .. .  .||  .
FEKIGELGHG-NGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQVLHECNS-PYIVGFYGAFYSDGEISICMEYMDGGSLDQVLKKAGRIPEKI

CGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAETIGVNSFVGTATYMSPERIQGRRYSTPSDIWSVGVVV
 | ..  .|. |. |. | .|            .|||.||.|.|    | .|| |||..        ||||||  ||||||.||  |.  |||||.|. .
LGKVSVAVLRGLTYLRDKHKI------------MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYTVQSDIWSMGLSL

AQMLLGHYP
  |..| ||
VEMAIGRYP
Kinase LmjF34.2090.AA Ciliate-E2-Unclassified 59-326 21 4.5e-37 126.14 In-house 2-352 (352) Show / Hide 
Range on Protein: 59-326
Range on HMM: 2-352/352
Sequence Identity: 21% (78 aa)

KRVRQLGQGTQGNVSMYVT-ADKSVFAVKKITIPVTLDT-RTRQTV--------AAELRN-------------IFSAQSNEYTVNLYNAFYRNRALRLVM
| ..|.||| .| | . .   .|  ....|. . .  .  .  ...        . . ..             |..   ... |... .|     . .||
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYMDWGNIDELIAEK-----------------VKIPPTVCG-----YIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTG---CVKL
||.. |.  . | ..                  ...   .      ... | | .|  || | ||            ||||||| |.|..  |   ..|.
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNI------------IHRDIKPENILFDNNGKNYYIKI

ADFGIATSAE-----------------TIGVNSFVGTATYM----SPERIQGRRYSTP----SDIWSVGVVVAQMLLGHYPFSS-VGKG-----------
.||||.   .                     ..|.||  ||    .|| .||  |...    .||||.||.  .|| | |||..   .            
IDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN

--FMALLREI-NSVEKYPLMEE----TGCSQEAQDFID----SCLRQDPDDRSSAFELLESPWI
  .. |...| .   ..| ...     . |.||.|||     ..|  .|. | .. ..|. ||.
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF34.2090.AA STE11 191-326 31 9.2e-37 128.46 In-house 138-303 (303) Show / Hide 
Range on Protein: 191-326
Range on HMM: 138-303/303
Sequence Identity: 31% (52 aa)

IHRDIKPANVLLSTTGC-VKLADFGIATSAETIG------------VNSFVGTAT--------YMSPERIQGRR---YSTPSDIWSVGVVVAQMLLGHYP
||||||.||.|| ..|. .||||||.|.. ..|.             .|. ||          .|.|| | .     |....||||.| .|  |. |  |
IHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPP

FSSVGK-GFMALLREINS-VEKYPLMEETG----CSQEAQDFIDSCLRQDPDDRSSAFELLESPWI
..  .   . |. . . .    .|. |.       |.|..||.. |. .|| .| .| .||. |.|
WHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase LmjF34.2090.AA MEK5 58-326 28 2.4e-33 117.09 In-house 1-254 (254) Show / Hide 
Range on Protein: 58-326
Range on HMM: 1-254/254
Sequence Identity: 28% (78 aa)

LKRVRQLGQGTQGNV-SMYVTADKSVFAVKKITIPVTLDTRTRQTVAAELRNIFSAQSNEYTVNLYNAFYRNRALRLVMEYMDWGNIDELIAEKVKIPPT
..    || |  | |   |      ..||| | . .||.   .. . .||  ..   |  | .  | ||.    . .  |.|| | .|       .||  
IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLE--LQKQIMSELEILYKCDS-PYIIGFYGAFFVENRISICTEFMDGGSLDMYR----CIPEH

VCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSAETIGVNSFVGTATYMSPERIQGRRYSTPSDIWSVGVV
. | ..  .   |  |              .|. .|||.||.|.|  | | .|| |||..|         ..||  || |||| | .|   ||.||.|. 
ILGRMTVAIVKGLNYLW-------------NLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITRTYIGTNAYMAPERISGDQYGIHSDVWSLGIF

VAQMLLGHYPFSSVGKGF-----MALLREINSVEKYPLMEETGCSQEAQDFIDSCLRQDPDDRSSAFELLESPWI
.  | .| .|.  . .       ..||  |   |. | .     |.   .||  |... | ||    .|.. |.|
FMEMATGRFPYPQIQRDQGELMPIQLLQCIVD-EHPPRLPVDKFSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI
Kinase LmjF34.2090.AA STE7-Unclassified 58-179 27 1.7e-13 44.0 In-house 1-142 (301) Show / Hide 
Range on Protein: 58-179
Range on HMM: 1-142/301
Sequence Identity: 27% (40 aa)

LKRVRQLGQGTQGNVSM-YVTA------DKSVFAVKKITIPVTLDTRTRQTVAAELRNIFSAQSNEYTVNLYNAFYRNRA---LRLVMEYMDWGNID---
|.|.. || |  |.|.. .  .      |. ..| |.|.  .  |   ..    ||  ... |  .| |  | |.|       . ..||||| | .|   
LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPT-MDNDNEFMKQILRELKTLHKCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKI

ELIAEKVK--------IPPTVCGYIASQMLHALAVLHTKSNIV
..  . ..        ||  | |.|| | .|.|  || | .|.
DIYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHII
Kinase LmjF34.2090.AA TyrKc 58-324 19 3.7e-12 -26.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 58-324
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

LKRVRQLGQGTQGNVSMYVTADKSVFAVKKITIPVTLDTRTRQTVAAELRNIFSA-QSNEYTVNLYNAFYRN-------RALRLVMEYMDWGNIDELIAE
..  ..|| |  | |   .     | |||..          |.    |.|   .   ...  |.|| .             | .|||||..|. .. . .
ITLGKKLGEGAFGEVYKGTWK-IQV-AVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KVK-IPPTVCGYIASQMLHALAVLHTKSNIVTEPNQHKSLRQIHRDIKPANVLLSTTGCVKLADFGIATSA----------ETIGV----NS-FVGTATY
. . ...    ... |     . || |             . ||||.   |.|..  ..|| .||| .             ... .    .. ..     
HRPKLCMKDLLSFCWQIACGMEYLHSK-------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MSPERIQGRRYSTPSDIWSVGVVVAQML-LGHYPFSS------VGKGFMALLREINSVEKYPLMEETG----CSQEAQDFIDSCLRQDPDDRSSAFELLE
|.|| |. ....| ||.|| ||.   .. .|  | .         .  ...... .  .. |  ..      |..|  . . .| . ||.|| .  |. |
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

SP
  
CF
Kinase LmjF34.2090.AA MEK1 285-326 35 2e-06 17.13 In-house 256-297 (297) Show / Hide 
Range on Protein: 285-326
Range on HMM: 256-297/297
Sequence Identity: 35% (15 aa)

EKYPLMEETGCSQEAQDFIDSCLRQDPDDRSSAFELLESPWI
|. | ...   |.| |||.| ||.. ||.|    .|.  ..|
EPPPKLPHRVFSEEFQDFVDKCLIKNPDERADLKQLMVHTFI
Kinase LmjF34.2090.AA Pkinase_Tyr 191-216 46 0.001581 12.57 Pfam 133-158 (270) Show / Hide 
Range on Protein: 191-216
Range on HMM: 133-158/270
Sequence Identity: 46% (12 aa)

IHRDIKPANVLLSTTGCVKLADFGIA
||||.   |.|.. ...|| .||| |
IHRDLAARNCLVTENNVVKICDFGLA
Kinase LmjF34.2090.AA Pkinase_Tyr 234-256 47 0.014908 9.27 Pfam 181-203 (270) Show / Hide 
Range on Protein: 234-256
Range on HMM: 181-203/270
Sequence Identity: 47% (11 aa)

MSPERIQGRRYSTPSDIWSVGVV
|.|| |. ....| ||.|| ||.
MAPECINYGKFTTKSDVWSFGVL