Gene 87430.m00080 (T.vaginalis)

87430.m00080

Species: T.vaginalis
Alias: 87430.m00080, TvagK0962
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
87430.m00080.AA Protein None 333 None Fasta, JSON
87430.m00080.kin_dom Protein Kinase Domain None 220 None Fasta, JSON

Protein domain

Protein domains of 87430.m00080.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87430.m00080.AA Ciliate-E2 78-287 17 6.5e-28 92.88 In-house 51-365 (365) Show / Hide 
Range on Protein: 78-287
Range on HMM: 51-365/365
Sequence Identity: 17% (55 aa)

AIKFMPKRRSISIRNKRQVS--------------IFSTISHTNIIKISQYIQ--AAKYYIYVTPYYNLGDLYFALLEREMK----------FTIQQVAKM
|.| | |.  ..| .. ..               | ....| ||||.  . |    ... .|. |.. |||.  . ..  |          ||.......
AMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYI

MWGLID---------------LLNYLHNRN-IVHGNISLENIILESESKAILTGFSHASEQFIE---------VNDYKKTV-------------------
|. ...                |.|||..| |.| .| .|||..       .. |  . .. ..          . |.                      
MKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMF

--------FIAPEVEQNRI---------LNFSTDIFALGTAFYFLLTK----------CNVNITSIDMDDD---------ISQKLCPSARNLLSG----M
        . |||. ..            ... ||..||  .|..|..          |.... . ....|         . .|. ... .|..     |
NTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRM

LKPNPAERFG-MNQIIAHEFF
|. .| .|.. ..||. |..|
LQKDPEKRITGWEQILNHPWF
Kinase 87430.m00080.AA Ciliate-E2-Unclassified 78-287 18 2e-19 64.02 In-house 28-352 (352) Show / Hide 
Range on Protein: 78-287
Range on HMM: 28-352/352
Sequence Identity: 18% (59 aa)

AIKFMPKRRSIS---------------IRNKRQ---VS--------IFSTISHTNIIKISQYIQAAKYYIYVTPYYNLGDLYFALLEREM----------
|.| | | ....               . |...   ..        |.. . | .|.|   . |  .. . |. | . ||| . . .|.           
AMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFH

------KFTIQQVA-----KMMWGLIDLLNYLHNRN-IVHGNISLENIILESES---KAILTGFSHAS---------------EQFIEVNDYKKTV----
      .|| ||..     .... ... |.|||  | |.| .| .|||.. ..    .  ...|. ..                |..  . .. ..    
NMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPN

FI----APEVEQNRILN----FSTDIFALGTAFYFLLT--KCNVNITSID----------------MDDDISQK---------------LCPSARNLLS-
..    |||| |.   .    .. ||..||  .|..|.   .    ....                . ..| ||               . |.| .... 
YMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIND

---GMLKPNPAERFGMNQIIAHEFF
    ||| || .| ...||. | .|
LLQKMLKKNPNKRITFEQILNHPWF
S_TKc 87430.m00080.AA S_TKc 51-287 19 7.1e-16 55.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 51-287
Range on HMM: 1-231/231
Sequence Identity: 19% (49 aa)

YNIICNLSENDDSNCFYAINMDTHAKCAIKFMPKRRSISIRNKRQVSIFSTISHTNIIKISQYIQAAKYYIYVTPYYNL--GDLYFALLEREMK-----F
| |.  . .   . .. ... .|. ..||| ..      .. .| ..| .   | ||.|.  ..|  ...  |. | .   |||.  . .|  .     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TIQQVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESESKAILTGFSHASEQFIEVNDYKKTV-FIAPEVEQNRILNF-STDIFALGTAFYFLLTKCNV
.  .....|. ... |.|.|...|.|  .  ||| | .     .. |  | .     . .  |  ..||||      .. . |. ..|  .| .|. .  
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPP

NITSIDMDDDISQKLC-PSARNLLSGMLKPNPAERFGMNQIIA-------HEFF
       .. . .|.. |.|.......|. .|..| .  .. .       |..|
FP----QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87430.m00080.AA Ciliate-E2a 96-183 29 5.6e-14 37.56 In-house 50-142 (275) Show / Hide 
Range on Protein: 96-183
Range on HMM: 50-142/275
Sequence Identity: 29% (27 aa)

VSIFSTISHTNIIKISQYIQAAKYYIYVTPYYNLGDLYFALLERE-MKFTIQQVAKMMWGLI-DLLNYLHNRNIVHGNISLENIILE---SES
..| ....| ||||.  . .  ..| .|. |.. |.||  . .   ... ||.....|. |. . |.|.|.|||.|  . .|||...   ..|
INIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNS
Kinase 87430.m00080.AA CAMK 72-190 14 5e-12 34.32 In-house 30-240 (425) Show / Hide 
Range on Protein: 72-190
Range on HMM: 30-240/425
Sequence Identity: 14% (31 aa)

DTHAKCAIKFMPKRRSIS---------------------------IRN--KRQVSIFST-------ISHTNIIKISQYIQ--------------------
. . |.|||...|..  .                            |   .| ..| ..       ..| ||||. ....                    
N-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTK

AAKYYIYV--TPYYNLGDL--Y-FALLERE---------------MKFTIQQVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESES------------
  ..|.    . |   |.|  . |  . .                 .|| ........ ... ..|.|..||||  . .||| | . .            
DKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIF

-----KAILTGF
     .  .. |
DWNNNNIKIIDF
Kinase 87430.m00080.AA AGC 254-287 22 9.6e-12 25.14 In-house 352-395 (395) Show / Hide 
Range on Protein: 254-287
Range on HMM: 352-395/395
Sequence Identity: 22% (10 aa)

QKLCPSARNLLSGMLKPNPAERFG----------MNQIIAHEFF
... | |..|....|...|..| |           ..| .|..|
RWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 87430.m00080.AA DCAMKL 96-176 41 6.4e-11 29.65 In-house 66-145 (279) Show / Hide 
Range on Protein: 96-176
Range on HMM: 66-145/279
Sequence Identity: 41% (34 aa)

VSIFSTISHTNIIK-ISQYIQAAKYYIYVTPYYNLGDLYFALLEREMKFTIQQVAKMMWGLIDLLNYLHNRNIVHGNISLEN
||| . |.|..||. . .. ....||. |  |   |||. |. |   |||  . | ||  |   |.||| .||||  | .||
VSIMQKIKHPHIIQLYEHWDTETHYYL-VMEYVQGGDLFDAITE-NTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPEN
Kinase 87430.m00080.AA CAMK-Unique 68-182 18 1.1e-10 31.26 In-house 18-193 (363) Show / Hide 
Range on Protein: 68-182
Range on HMM: 18-193/363
Sequence Identity: 18% (32 aa)

AINMDTHAKCAIKFMPKRRSISIRNKRQ---------------------VSIFSTISHTNIIKISQY----IQAAK---------------YYIYVTPYY
...  |  |.|.|   | .  ....| |                     ..|  . .| ||||. ..     . .|               |.  |. | 
CMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYC

NLGDLYFALLER-------------------EMKFTI--QQVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESE
. |||. .....                   . .|.    ...  |  |   ..|.|. .|||... |||| . ..
QGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYS
Kinase 87430.m00080.AA CAMKL 68-179 20 5.9e-10 27.81 In-house 18-160 (297) Show / Hide 
Range on Protein: 68-179
Range on HMM: 18-160/297
Sequence Identity: 20% (29 aa)

AIN-MDTHAKCAIKFMPKRRSISIRNKRQ----------------VSIFSTIS---HTNIIKISQYIQAAKY------YIYVTPYYNLGD--LYFALLER
|.. . |  | |||.. |..   . ....                ..| . ..   | ||||. . |.  ..      .  |. |   |.  |.  . ..
ATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKH

E---MKFTIQQVAKMMWGLIDLLNYLHNRNIVHGNISLENIIL
.    ...  .  .. . ... .||.|...|||  | .||| |
GHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILL
Kinase 87430.m00080.AA CAMK 247-287 24 9e-10 26.92 In-house 381-425 (425) Show / Hide 
Range on Protein: 247-287
Range on HMM: 381-425/425
Sequence Identity: 24% (11 aa)

DMDDDISQK----LCPSARNLLSGMLKPNPAERFGMNQIIAHEFF
. .||||.     . .....|...||...| .|.   |. .|...
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 87430.m00080.AA SAK 51-237 22 1.4e-09 28.48 In-house 1-195 (254) Show / Hide 
Range on Protein: 51-237
Range on HMM: 1-195/254
Sequence Identity: 22% (44 aa)

YNIICNLSENDDSNCFYAINMDTHAKCAIKFMPKR----RSISIRNKRQVSIFSTISHTNIIKISQYIQAAKYYIYVTPYYNLGDLYFALLEREMKFTIQ
|..   |        . |  . ||   ||| . |.      .  | .. | | . . |  |... .| . . |   |      |..   . .|   || .
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

QVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESESKAILTGFSHASEQFIEVNDYKKTV-----FIAPEVEQNRILNFSTDIFALGTAFYFLLT
  ...|  ..  . |||  .|.|  ..| ||.|  . .  .  |  |. |    ..   |.     .|.||.         .|...||  .| ||.
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLAT-QLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLI
Kinase 87430.m00080.AA CAMKL 259-287 34 1.4e-09 26.57 In-house 269-297 (297) Show / Hide 
Range on Protein: 259-287
Range on HMM: 269-297/297
Sequence Identity: 34% (10 aa)

SARNLLSGMLKPNPAERFGMNQIIAHEFF
..|.|...||..|| .|. . ||  |...
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 87430.m00080.AA Pkinase 78-169 23 1.9e-09 34.47 Pfam 28-131 (293) Show / Hide 
Range on Protein: 78-169
Range on HMM: 28-131/293
Sequence Identity: 23% (25 aa)

AIKFMPKRRSISIRNKR-----QVSIFSTISHTNIIKISQYIQAAKYYIY-VTPYYNLG----DLYFALL-EREMKF--TIQQVAKMMWGLIDLLNYLHN
|.| ..||.  |  ...      ..|   ..| ||...  . .  | .|| |..| . |    ||.  .  .|. .|  . ... ..|. ..  |.|.|.
AVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS

RNIVH
..|.|
MGIIH
Kinase 87430.m00080.AA PLK1 51-236 23 1.8e-08 23.66 In-house 1-193 (253) Show / Hide 
Range on Protein: 51-236
Range on HMM: 1-193/253
Sequence Identity: 23% (47 aa)

YNIICNLSENDDSNCFYAINMDTHAKCAIKFMPKRRSISIRNK----RQVSIFSTISHTNIIKISQYIQAAKYYIYVTPYYNLGDLYFALLEREMKFTIQ
|.    | .     |.  .. ||.   | | .||   |    .    . ..|   ..| .|.|. ..    | ..|..         . |  |    | .
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFE-DKQNVYIVLELCRRRSLMELHKRRKAITEP

QVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESESKAILTGFSHASEQFIEVN-DYKKTV-----FIAPEVEQNRILNFSTDIFALGTAFYFLL
     |  ...   |||| .|.|  . | |. |. . .  .  |  |   ..| . . |||      .||||| ...   |  ||...|  .| ||
ECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLAT--KCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILL
Kinase 87430.m00080.AA Ciliate-E2a 254-287 26 3.6e-08 20.19 In-house 242-275 (275) Show / Hide 
Range on Protein: 254-287
Range on HMM: 242-275/275
Sequence Identity: 26% (9 aa)

QKLCPSARNLLSGMLKPNPAERFGMNQIIAHEFF
.|.  .. .|...||...| .|.  .|.  | .|
EKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
TyrKc 87430.m00080.AA TyrKc 36-287 14 4e-06 -123.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 36-287
Range on HMM: 1-280/280
Sequence Identity: 14% (45 aa)

VEKVSQAQE-----LLKGNNYNIICNLSENDDSNCFYAINMDTHAKCAIKFMPKRRSISIRNKRQVSIFSTI--SHTNIIKISQYIQAA-------KYYI
...  .  |       ||  .                        ..|.| . .         |  .| . .  .| ||...  ..          . . 
ITLGKKLGEGAFGEVYKGTWK-----------------------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM

YVTPYYNLGDLYFALLEREMKFTIQQVAKMMWGLIDLLNYLHNRNIVHGNISLENIILESE----------SKAILTG-FSHASEQFIEVND--YKKTVF
 |. |  .|||   | ... |.. ..  ...|   .  .||| .|..|  .   |. . ..          |..|  .  . .|.. . .     .||..
IVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

----IAPEVEQNRILNFSTD----------IFALGTAFYFLLTKCNVNITSIDMDDDISQK---LCPSA-------------RNLLSGMLKPNPAERFGM
     |||. . .. .. .|          || .|   |   ..    .. ...  .. |     .|                .. .   . .|..|  .
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

NQIIAHEFF
..|  ||.|
SEI--HECF
Kinase 87430.m00080.AA AGC 72-182 16 8e-06 9.42 In-house 28-191 (395) Show / Hide 
Range on Protein: 72-182
Range on HMM: 28-191/395
Sequence Identity: 16% (27 aa)

DTHAKCAIKFMPKRR-SISIR--NKRQ----------------VSIFSTIS----------HTNIIK-ISQYIQAAKY--YIYVTPYYN--------LGD
||   .|.| . |..  . ..    ..                  |.....          | .|.|      |  ..     |  |..         |.
DTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGG

-LYFALLE---REMKFTIQQVAKMMW-------GLIDLLNYLHN-RNIVHGN-ISLENIILESE
  .|  |    .| .|. ...  ..         ..  | |||. ..|.|   . .||| | ..
CELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED
Kinase 87430.m00080.AA PLK1 252-287 33 8e-06 14.79 In-house 218-253 (253) Show / Hide 
Range on Protein: 252-287
Range on HMM: 218-253/253
Sequence Identity: 33% (12 aa)

ISQKLCPSARNLLSGMLKPNPAERFGMNQIIAHEFF
| ... . |..|.  ||.|.| .|  ..|..  |||
IPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 87430.m00080.AA Pkinase 258-287 23 1.5e-05 20.7 Pfam 264-293 (293) Show / Hide 
Range on Protein: 258-287
Range on HMM: 264-293/293
Sequence Identity: 23% (7 aa)

PSARNLLSGMLKPNPAERFGMNQIIAHEFF
.... .....|...|..| .  ||  |..|
EECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87430.m00080.AA SAK 260-287 35 0.0001 11.72 In-house 227-254 (254) Show / Hide 
Range on Protein: 260-287
Range on HMM: 227-254/254
Sequence Identity: 35% (10 aa)

ARNLLSGMLKPNPAERFGMNQIIAHEFF
|. |.  ||. ||.|| ... .. | | 
AQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase 87430.m00080.AA DCAMKL 259-287 37 0.000336 8.36 In-house 251-279 (279) Show / Hide 
Range on Protein: 259-287
Range on HMM: 251-279/279
Sequence Identity: 37% (11 aa)

SARNLLSGMLKPNPAERFGMNQIIAHEFF
||..| | ||. .|  |.   || .|   
SAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase 87430.m00080.AA CAMK-Unique 258-287 13 0.006092 5.32 In-house 334-363 (363) Show / Hide 
Range on Protein: 258-287
Range on HMM: 334-363/363
Sequence Identity: 13% (4 aa)

PSARNLLSGMLKPNPAERFGMNQIIAHEFF
..| ... . ..  |. |   .... |...
QEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 87430.m00080.AA Ciliate-E2a 208-237 30 0.009691 3.92 In-house 176-211 (275) Show / Hide 
Range on Protein: 208-237
Range on HMM: 176-211/275
Sequence Identity: 30% (11 aa)

FIAPEVEQNRI------LNFSTDIFALGTAFYFLLT
..||||  |.          . |.. .|  ||.||.
YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLC