Gene 95305.m00245 (T.vaginalis)

95305.m00245

Species: T.vaginalis
Alias: TvagK0738, 95305.m00245
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
95305.m00245.AA Protein None 442 None Fasta, JSON
95305.m00245.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of 95305.m00245.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD 95305.m00245.AA PBD 14-48 28 0.000968 17.01 SMART 1-38 (38) Show / Hide 
Range on Protein: 14-48
Range on HMM: 1-38/38
Sequence Identity: 28% (11 aa)

ISDPF-DVKKHVHVT-LDS-TGTYQNIPRSMLSAIPIA
|| |. ..|  |||   |  ||.....| .  . ..  
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
PBD 95305.m00245.AA PBD 13-40 33 0.007233 12.97 Pfam 1-30 (60) Show / Hide 
Range on Protein: 13-40
Range on HMM: 1-30/60
Sequence Identity: 33% (10 aa)

EISDP-FDVKKHVHVTLDS-TGTYQNIPRS
.|| | ...| ..||. |. ||.. . |..
MISTPLTNFKHTMHVGWDGQTGFFTGMPPE
PBD 95305.m00245.AA PBD 74-131 41 6.4e-21 75.55 Pfam 1-60 (60) Show / Hide 
Range on Protein: 74-131
Range on HMM: 1-60/60
Sequence Identity: 41% (25 aa)

RISKP-TDVEHKIHVTMDSENG-FVGLPPEFEKLLKGSGITKEEAVAHPENTVNVLNFFN
 ||.| |...|..||. |...| |.|.||| .|||..|||.|.|   .|. .. |. | .
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD 95305.m00245.AA PBD 75-109 39 5.4e-11 43.76 SMART 1-38 (38) Show / Hide 
Range on Protein: 75-109
Range on HMM: 1-38/38
Sequence Identity: 39% (15 aa)

ISKPT-DVEHKIHVT-MDS-ENGFVGLPPEFEKLLKGS
|| || ...|..||   |  . .|.|||.. ..||| .
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase 95305.m00245.AA PAKA 169-414 44 7.50000000001e-118 397.83 In-house 4-260 (260) Show / Hide 
Range on Protein: 169-414
Range on HMM: 4-260/260
Sequence Identity: 44% (115 aa)

MQKLDEGSTCTVYTAMYHGRK----VAVKEMLLNEKNEK-NLLDETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDGGALTNVATFCD------CQEP
|.|. .|....||.|   . .    ||.| | ... . | ... | ..| . . . ||...|.| |   ||..||||.|| || | | |.       .| 
MEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYMDEG

HIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELIQAFPYGFAVDIWSLGILCRELAEGEPPY
.|||  | .| .|...|... |||||| ||.||   |.||..|||. ||||    ||...||||||||||.|.   |.  ||||||||...|..||||||
QIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEPPY

VTEPPMRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
  ||| ||..|| . |.|.| ...  |.|| |||..||. ..  |.|| |||.|||.
LNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 95305.m00245.AA STE20 166-414 42 3.8e-116 392.16 In-house 1-288 (288) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-288/288
Sequence Identity: 42% (123 aa)

LIDMQKLDEGSTCTVYTAMYH---GRK----VAVKEMLLNEK----NEK-NLLDETRLMYSMQDDHIVKFYDAYRVG----NTLWIIMEYMDGGALTNVA
  ...|. .||...||.| ||   |..    ||.| | |...    .|. ... | . |   .  .|||.|..| ..    . |||.|||..|| || . 
YELLEKIGQGSYGKVYKA-YHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM

TFC-DCQ---------EPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTA----TAD-KRKSIVGTPYWMAPELIQA---
..|  |.         |..|||  |..| .|.| |....|||||| ||.||.| |.|||||||. ||||     | . ||...||||||||||.||    
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

--FPYGFAVDIWSLGILCRELAEGEPPYVTEPPMRALFLIV--SRGIPEISN--KEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
   .|.. .||||||| . |.|||||||  ..||||.|.|   ... |. ..  ..  |||| ||...|||..|. ||.| .||.||||
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 95305.m00245.AA STE 166-414 31 5.5e-108 365.05 In-house 1-359 (359) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-359/359
Sequence Identity: 31% (115 aa)

LIDMQKLDEGSTCTVYTAMYH-----------------GRKVAVKEMLLNEKN------------------EKNLLDETRLMYSMQ--DDHIVKFYDAYR
. ...|. .|.. |||.||.|                 |. .|.|.| |...|                  ....| | ..|  ..   ..|||.|..| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG-------NTLWIIMEYMDGGALTNVAT-FCDCQ--------------EPHIAYFARDILLA-LKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTA
..       ..|||.||||||| |. .    . |.              |. |||..|.|| . |.| | ...|||||| .|.||     |||.|||  .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTA---------------TAD-KRKSIVGTPYWMAPELIQA------FPYGFAVDIWSLGILCRELAEGEPPYVTEPPMRALFLIVSR-----------
|||                | . ||...|||| ||||| ||        .|.. .||||||... |.|.|.||. ...||||.|.|              
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GIPEISN-----------------KEVRSPEFIDFLNRCLQRNPAMRPSAAELLE--HPFI
    ..| . .                 ..  ||||.||.|.|||..|  ||.| .||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95305.m00245.AA PAKB 166-414 48 1.1e-89 304.2 In-house 1-252 (252) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-252/252
Sequence Identity: 48% (122 aa)

LIDMQKLDEGSTCTVYTAMYH--GRKVAVKEMLLNEKNEKNLL-DETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDGGALTNVATFCDCQEPHIAYF
| .  |  |||| .|  |     || |||| | |       ||  |   |   | . ||..|. | ||. ||..||.|.||||| . |    .|. ||. 
LDNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTRMNEEQIATV

ARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELIQAFPYGFAVDIWSLGILCRELAEGEPPYVTEPP
 | .| || |.|||  |||||| | .|| . |.||| |||. ||.     |||| ||||||||||.|   |||  ||||||||.  |. .|||||  |||
CRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPP

MRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
..|.  |     | ..|    ||.  .||.|.| |.|. | .|.|||.|||.
LQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase 95305.m00245.AA YSK 220-414 48 9.4e-88 264.26 In-house 59-257 (257) Show / Hide 
Range on Protein: 220-414
Range on HMM: 59-257/257
Sequence Identity: 48% (97 aa)

IVKFYDAYRVGNTLWIIMEYMDGGALTNVATF---CDCQEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKS
| |.| .|  .  |||||||  || .            .|..||   | ||..|.|.| ..|||||||  |||||| |.|||.|||  .|.| |  ||  
ITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNT

IVGTPYWMAPELIQA--FPYGFAVDIWSLGILCRELAEGEPPYVTEPPMRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
 ||||||||||.|.     | | .|||||||   |.| |||||    |||..|||...  |. . ..  |  |..| . ||  .|. |||| ||| | ||
FVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLE-GRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 95305.m00245.AA S_TKc 166-414 29 6e-82 279.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

LIDMQKLDEGSTCTVYTAMYHG--RKVAVKEMLLNEKNEKNLLDETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDG--GALTNVATFCDC-------
   ..|. .|.  .|| .  ..  |.||.|..       .... | ... . . ..|||.||...  . |...|||.||  | |  .   . .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELIQAFPYGF-AVDIWSLGILCRELAEG
 | |...... |..||.|.| .. ||||.| .|.||.|   .|..|||  .||       ....|||..||||..   .||. ..|.||.|..  |.. |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

EPPYVTEPPMRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLE-------HPFI
.||.     | ..| ..             |||..||...|||..|. ||.| |.|.       ||..
YPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95305.m00245.AA MST 169-414 43 4.8e-81 257.35 In-house 4-254 (254) Show / Hide 
Range on Protein: 169-414
Range on HMM: 4-254/254
Sequence Identity: 43% (109 aa)

MQKLDEGSTCTVYTAMYH--GRKVAVKEMLLNEKNEKNLLDETRLMYSMQDDHIVKFYDAYR--VGNTLWIIMEYMDGGALTNV--ATFCDCQEPHIAYF
. || .||   || | .   |  ||.| .   .    ... | . |  .. ..|||.|. |.    |..||.||| ..| .  .  .|     |  ||  
VEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIACI

ARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELIQAFPYGFAVDIWSLGILCRELAEGEPPYVTEPP
 .| |. |.| |   |||||||  | ||.. |  ||||||  .||| |  || . .||||||||| ||   |   .||||||| . |.|||.|||    |
LYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHP

MRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
|||.|.| .. .|  .. |  |.||.||. .|||.||  |..| .||.||||
MRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 95305.m00245.AA Pkinase 166-414 25 3.9e-69 240.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LIDMQKLDEGSTCTVYTAMYHGRK--VAVKEMLLNEKNEKNL-----LDETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDGG----ALT------NV
.   .|. .||  .|| .. .|    ||||.. . ..... .     | | ..| ... ..||..||... .. ....|||..||     |       . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ATFCDCQEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKV----KLADFGYTAQL-TATADKRKSIVGTPYWMAPELIQ-AFPYGFAVDIWS
 .|   .| ..  ... || .|.|.|... ||||.| .|.|....| .    |..|||  .|. .      ....|||..||||.|. . .|| .||.||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGILCRELAEGEPPYVTE----PPMRALFLIVSRGI--PEISNKEVRS-------------------PEFIDFLNRCLQRNPAMRPSAAELLEHPFI
.|... |.. |.||.  .    . .. ...|. ..   .. .  . .|                   .|..||...||...|. ||.|...|.||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95305.m00245.AA SLK 169-414 36 2.2e-64 216.07 In-house 4-259 (259) Show / Hide 
Range on Protein: 169-414
Range on HMM: 4-259/259
Sequence Identity: 36% (93 aa)

MQKLDEGSTCTVYTAMYHGRKVAVKEMLLNEKNEKNLLD---ETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDGGALTNVATFCD--CQEPHIAYFA
.  | .|    || |  . .||      .. |.| .| |   |  .. ...  .||| |.|| . | ||...|. ||||. |.    .   .|. |.| .
IGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQYVC

RDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELI-----QAFPYGFAVDIWSLGILCRELAEGEPPYV
. .. ||...| .. ||||.|  |.|.   |.|.|||||  |... | .|| . .|||||||||..     .  || . .|||||||   |.|..|||. 
KHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPPHH

TEPPMRALFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
   ||| |. |     |.. .    | || ||| .||...|  |...|.|..|...
EMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 95305.m00245.AA KHS 169-414 39 4.1e-64 214.49 In-house 4-258 (258) Show / Hide 
Range on Protein: 169-414
Range on HMM: 4-258/258
Sequence Identity: 39% (101 aa)

MQKLDEGSTCTVYTA--MYHGRKVAVKEMLLNEKNEKNLL-DETRLMYSMQDDHIVKFYDAYRVGNTLWIIMEYMDGGALTNVATFC-DCQEPHIAYFAR
.|..  |    || |  .  .  .||| . ..  ..  ..  |  .|   .   || .. .|   . |||.|||  ||.| ..       .|  ||| .|
LQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCR

DILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADKRKSIVGTPYWMAPELI---QAFPYGFAVDIWSLGILCRELAEGEPPYVTEP
..| .|.|.|.. |.|||||  |.||...|.||||||| .||.|||  |||| .|||||||||     .   |.   |||..||   ||||  ||     
ETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPMFDLH

PMRALFLIVSRGI--PEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
|||||||.   .   |.. .|.  |. | .|.  .| .||  ||.|  ||.|||.
PMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 95305.m00245.AA MKC 220-414 35 7.4e-63 215.13 In-house 63-260 (260) Show / Hide 
Range on Protein: 220-414
Range on HMM: 63-260/260
Sequence Identity: 35% (73 aa)

IVKFYDAYRVGN-TLWIIMEYMDGGALTNVATF-CDCQEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATADK-RKS
|||.. .. ... ..|..||.|.|| |.. .      .|  ||| .. .| .| | |..| .|||.|  |.  .  |..|| |||    | . . . ...
IVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHKFCESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFG----LCIDVSHEKEE

I--VGTPYWMAPELIQAFPYGFAVDIWSLGILCRELAEGEPPYVTEPPMRALFLIVSRGIPE---ISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEH
|  .| |.||.|| ||  ... ..||||.||   |.| |.||.  . .| | |.  . |.        ..  |..| |||. ||| .|. ||.| .|| |
IHMCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPPH-HKSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKH

PFI
|||
PFI
Kinase 95305.m00245.AA PAKL 267-414 48 2e-58 200.42 In-house 108-256 (256) Show / Hide 
Range on Protein: 267-414
Range on HMM: 108-256/256
Sequence Identity: 48% (72 aa)

LLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTATAD-KRKSIVGTPYWMAPELIQAFPYGFAVDIWSLGILCRELAEGEPPYVTEPPMRA
|. | | | .| ||||||  |.||.|.. ||.||||   ||  . |   ....||||||||| |   .|   .|||||||   |.|.|.||  . |||||
LKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRA

LFLIVSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
.  |  .  |  ||    ||.| ||| .|..  |  |.|. .|| ||||
MYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 95305.m00245.AA TyrKc 166-414 22 8.2e-26 93.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 166-414
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

LIDMQKLDEGSTCTVYTAMYHGRKVAVKEMLLNEKNEKNLLDETRLMYSM--QDDHIVKFYDAYRVG-------NTLWIIMEYMDGGALTNVATFCD--C
.   .|| ||  ..|| ...  ..|||| .  .   .. ...| |.| .   . ..||..| . . .         |.|.||||..|.| .    .    
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

QEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFGYTAQLTAT-------ADKRKSI-VGTP-----YWMAPELIQAFPYGFAVDIW
. ..  .|. .|     | | .| ||||. . |.|..| . || .||| .  ..           .||.   |.       ||||| |.   . .. |.|
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SLGILCRELAE-GEPPYVT-----EPPMRALFLIVSRGIPEISNKEV------RSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
| |... |.   |..||        .. ... .. ... ...            ..|  .   .| ...|..||. .|.  | ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 95305.m00245.AA Pkinase_Tyr 166-302 24 6.7e-16 54.48 Pfam 1-156 (270) Show / Hide 
Range on Protein: 166-302
Range on HMM: 1-156/270
Sequence Identity: 24% (38 aa)

LIDMQKLDEGSTCTVYTAMYH------GRKVAVKEM--LLNEKN--EKNLLDETRLMYSM-QDDHIVKFYDAYR-VGNT--LWIIMEYMDGGALTNVATF
.. ..|| ||.  .|| . ..      . .|||| .     ...   . .. | ..| .. . ..||..| .    |    ..|.|||| .| | .    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

C-----DCQEPHIAYFARDILLALKYMHAQNKIHRDIKTDNVLLSETGKVKLADFG
          ...  ....|  .. | ...| ||||. . |.|..|...|| .|||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 95305.m00245.AA Pkinase_Tyr 323-414 27 1e-06 23.41 Pfam 180-270 (270) Show / Hide 
Range on Protein: 323-414
Range on HMM: 180-270/270
Sequence Identity: 27% (26 aa)

WMAPELIQAFPYGFAVDIWSLGILCRELAE-GEPP-YVTEPPMRALFLI-VSRGIPEISNKEVRSPEFIDFLNRCLQRNPAMRPSAAELLEHPFI
||||| |.   .  . |.|| |.|. |.   || | |   .. . . .|  ...  ..   |  ..|  | . .| . .|..||. .|.  | ..
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC--PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL