87955.m00279

Species: T.vaginalis
Alias: 87955.m00279, TvagK0065
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87955.m00279.AA Protein None 231 None Fasta, JSON
87955.m00279.kin_dom Protein Kinase Domain None 171 None Fasta, JSON

Protein domain

Protein domains of 87955.m00279.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87955.m00279.AA CAMKL 3-174 35 4.8e-63 199.98 In-house 99-293 (297) Show / Hide
Range on Protein: 3-174
Range on HMM: 99-293/297
Sequence Identity: 35% (71 aa)

IQEYCSGGE--MFTKV--RTGPN--IRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGD--AKIIDFGLSEVVN------DVNLKTHCGTLI
. |||||||  .| ..  . ...  . |.|  ||  ||.||.||.| ..| |||||.||| ||.||.  .||||||.|          .  |||.||.. 
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YMAPEMLSQ--RQFDGKAVDIWAIGICIYAMVTRTFPWKSTT-------DEELLHEIIQADIFFPN---FVCPTISELLHGTLVKNPSERAPAAELIS
|||||...   ...||..||||..|.  ||||. ..|..  |       .  .|...|  . ..|.   .|      |... |..||..|. . .. .
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

Kinase 87955.m00279.AA CAMK 3-174 22 5.6e-59 188.37 In-house 135-421 (425) Show / Hide
Range on Protein: 3-174
Range on HMM: 135-421/425
Sequence Identity: 22% (64 aa)

IQ---EYCSGGEM----FTKVRTGPN---------------IRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNN-----------------GD
.    |||||||.    | ...  ..               . |.|  ||  ||.||..|.| .||.|||.|.||| ||.|                 ..
VMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNN

AKIIDFGLSEVVNDVN-------------------------LKTHCGTLIYMA-PEMLSQ-------------RQFDGKAVDIWAIGICIYAMVTRTFPW
 ||||||.. .... .                         .|| |||. ||| ||.|..             .. .|...|.|..|.  |.|.. ..|.
IKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF

KST-------------TDEELLHEIIQADIFFPNFVCPT------------------------ISELLHGTLVKNPSERAPAAELIS
 .              .|.||.. |....  || .  ..                           |. . |...|..|. ...  .
YGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN

Kinase 87955.m00279.AA AGC 5-166 22 7.6e-54 136.51 In-house 113-373 (395) Show / Hide
Range on Protein: 5-166
Range on HMM: 113-373/395
Sequence Identity: 22% (59 aa)

EYCS---------GG-EMFTKVR---TGPNIRESEIIRYSLQ-------IISAINYLHT-RNIMHRD-IKLENIVLDNNGDAKIIDFGLSEVVND-----
||..         || |.|.  .         |...  |  .       |..|. |||  ..| ||| .|.|||.||..|  |. ||||. ....     
EYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKG

-----------------------------------------------VNLKTHCG--TLIYMAPEMLSQRQFDGKAVDIWA--IGICIYAMVTRTFPWKS
                                               .  .| ||  |  |||||.|      |||.|.|.   |...| |.|   |  .
QQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYG

TTDE----------ELLHEII------QADIFFP----------NFVCPTISELLHGTLVKNPSER
 ...          |. . |.      . .. ||           .. |    |. . |.|.|..|
DNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR

Kinase 87955.m00279.AA MARK 5-174 40 7.8e-54 174.42 In-house 82-258 (262) Show / Hide
Range on Protein: 5-174
Range on HMM: 82-258/262
Sequence Identity: 40% (71 aa)

EYCSGGEMFTKVRTG--PNIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNG--DAKIIDFGLSEVV-NDVNLKTHCGTLIYMAPEMLSQRQ
||.||||..  ..      . |.|  |.  ||.||.||.| .|| |||||.||| .| ||  ..||||||.|  . ..  |.|.|||. |||||..... 
EYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKP

FDGKAVDIWAIGICIYAMVTRTFPWKSTT--DEELLHEIIQADIFFPNFVCPTISELLHGTLVKNPSERAPAAELIS
 ||..||||. |.  |.||. .||.. .|  ..||  .|   .  .| .| . .  |..  |. ||.||. . |. .
YDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK

Pkinase 87955.m00279.AA Pkinase 2-176 26 9.7e-51 179.68 Pfam 77-293 (293) Show / Hide
Range on Protein: 2-176
Range on HMM: 77-293/293
Sequence Identity: 26% (57 aa)

VIQEYCSGG----EMFTKVR--TGPNI--RESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGDA----KIIDFGLSE---VVNDVNLKTHCGT
...||| ||    . |. ..   . ..   | |...| .||.....|.| ..|.|||.|.||| .||||.     ||.||||..     |.. ..| |||
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT

LIYMAPEMLSQRQFDGKAVDIWAIGICIYAMVTRTFPWKST------TDEELLHEIIQADIFFPNFVC---------------------PTISELLHGTL
. ||||| .  .| .|..||.|..|. .| |... .|...       .. ... .| .... |. .                       ..  ... . |
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

VKNPSERAPAAELISI--I
 |.|..|  |...     .
CKDPKKRPTAEQILQHPWF

Kinase 87955.m00279.AA Ciliate-E2 3-166 24 8.8e-49 165.58 In-house 112-352 (365) Show / Hide
Range on Protein: 3-166
Range on HMM: 112-352/365
Sequence Identity: 24% (62 aa)

IQEYCSGGEMFTKVR------------TGPNIRESEIIRYSLQIIS---------------AINYLHTRN-IMHRDIKLENIVLDNNGDAKIIDFGLSEV
. |||.||..|   .               .. | ||.... ||..               |..||| .| |.|||||.|||..      ||||||||  
VMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKK

VNDVNLKTH---------------------------------CGTLIYMAPEMLSQRQFDG--------KAVDIWAIGICIYAMVTRTFPWKSTTDEELL
..| | ..                                  |||. |||||.|.  . |.        ...|||..|...| |..  .|.        .
YDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------Q

HEIIQADIFFP----------------NFVCPTIS--ELLHG----TLVKNPSER
 .|.| .| ||                ..   . .   |.       |.|.|..|
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR

Kinase 87955.m00279.AA Ciliate-E2-Unclassified 3-166 27 1.7e-48 166.32 In-house 99-340 (352) Show / Hide
Range on Protein: 3-166
Range on HMM: 99-340/352
Sequence Identity: 27% (67 aa)

IQEYCSGGEMFTKVRTGPN-----------------IRESEII-----RYSLQIISAINYLHTRN-IMHRDIKLENIVLDNNG---DAKIIDFGLSE---
. ||| ||...   .  ..                 . | ...     .|  ||.....|||  | | |||||.|||..||||     ||||||.|    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------VVNDVNLKTHCGTLIYM----APEMLSQRQFDG---KAVDIWAIGICIYAMVTRTFPWKSTTDEE----------------LLHEI
              .  . ...| |||..||    |||.| . . |.   ...|||. |...|.|.. ..| .....|.                |. .|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IQADIFFPNFVC----PTIS--------ELLHGTLVKNPSER
.| .|.||.|       ..|        .||.  |.|||..|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR

Kinase 87955.m00279.AA AMPK 2-167 38 3.4e-47 138.2 In-house 77-243 (254) Show / Hide
Range on Protein: 2-167
Range on HMM: 77-243/254
Sequence Identity: 38% (64 aa)

VIQEYCSGGEMFTKVRTGPNIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGDAKIIDFGLSEVVNDVN-LKTHCGTLIYMAPEMLSQRQF
.. || |||| |  .     . | |  |.  ||||.. |.|  .| ||| |.||. || |   || ||||| . .| . ||| ||   | |||| | .  
MVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLY

DGKAVDIWAIGICIYAMVTRTFPWKSTTDEELLHEIIQADIFFPNFVCPTISELLHGTLVKNPSERA
 |  ||||  |.  |||. .. |       .|   |.. .   | |. | ...|... | ..| .|.
CGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRI

Kinase 87955.m00279.AA ULK 3-166 25 4.2e-40 137.7 In-house 98-317 (329) Show / Hide
Range on Protein: 3-166
Range on HMM: 98-317/329
Sequence Identity: 25% (56 aa)

IQEYCSGGEMFTKVR----------TGPNIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNN------------GDAKIIDFGLSEVVNDVN-
|.||| ||  ..             .. .. |.|.| .  ||...  .|| .||.|||||..|| ..|.            | .|| |||.. .|.. | 
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNM

----LKTHC------GTLIYMAPEMLS----QRQFDGKAVDIWAIGICIYAMVTRTFP---WKSTTDE-----ELLHE-------IIQADIFFP-----N
    ..|        || .||||. |.    | ... . .||| .|. .| |..   |   |  ...      .|.         | .  . ||     .
EQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

FVCPTISELLHGTLVKNPSER
 . | . .|. . |......|
QISPECKDLIRRMLQYDEKDR

Kinase 87955.m00279.AA ULK 3-166 25 9.3e-39 135.08 In-house 95-312 (324) Show / Hide
Range on Protein: 3-166
Range on HMM: 95-312/324
Sequence Identity: 25% (56 aa)

IQEYCSGGEMFTKVR---------TGPNIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNN------------GDAKIIDFGLSEVVND----
|.||| ||  ..            .. .. |.|.| .  ||...  .|| .||.|||||..|| . |.            | .|| |||.. .|..    
IMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

-VNLKTHC------GTLIYMAPEMLS----QRQFDGKAVDIWAIGICIYAMVTRTFP---WKSTTDE----ELLHE-------IIQADIFFP-----NFV
   ..| .      || .||||. |.    | ... . .||| .|. .| |..   |   |  ....    .|..        | .  | ||     . .
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKI

CPTISELLHGTLVKNPSER
 | . .|. . |......|
SPECKDLIRRMLQYDEKDR

Kinase 87955.m00279.AA QIK 2-166 35 1.9e-38 134.06 In-house 75-260 (272) Show / Hide
Range on Protein: 2-166
Range on HMM: 75-260/272
Sequence Identity: 35% (66 aa)

VIQEYCSGGEMFTKVRT-GP-------------------NIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGDAKIIDFGLSEVVNDVN-L
.. ||||.||||  .   |                     . |.|  |   ||.||. |.| ||| |||.| ||| |||| . ||.|||.|        |
IVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLL

KTHCGTLIYMAPEMLSQRQFDGKAVDIWAIGICIYAMVTRTFPWKSTTDEELLHEIIQADIFFPNFVCPTISELLHGTLVKNPSER
.| ||.  | ||||.  ...||  |||| .|.  |..|.  .|  . |...| . ..      | |.     .|    || .|. |
MTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHR

S_TKc 87955.m00279.AA S_TKc 1-181 22 6.8e-24 86.62 SMART 19-231 (231) Show / Hide
Range on Protein: 1-181
Range on HMM: 19-231/231
Sequence Identity: 22% (54 aa)

MVIQ--------------------------------------------EYCSG--GEMFTKVRTGPN------IRESEIIRYSLQIISAINYLHTRNIMH
  .                                             |||.|  |..|.  .  .       . | .. .|  ||..|..|.| ..|.|
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIH

RDIKLENIVLDNNGDAKIIDFGLSEVVNDVNLKTHCGTLIYMAPEMLSQRQFDGKAVDIWAIGICIYAMVTRTFPWKSTTDEELLHEIIQADIFFPNFVC
||.| ||| ||.    ||.||||. ..     .| |||. |||||.|   .......|.|..|...| |...  |.    ..... ..|           
RDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------S

PTISELLHGTLVKNPSERAPAAELIS----IISRSAL
|   ... . |.|.|..|  | |.      | .   .
PEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

TyrKc 87955.m00279.AA TyrKc 1-176 14 1.7e-08 -85.43 SMART 1-280 (280) Show / Hide
Range on Protein: 1-176
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

MVIQEYCSGGE-------------------------------MFTKV--------------------------------------------RTGPNIRES
 .  .    |.                               . .|.                                            ...|..  .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

EIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGDAKIIDFGLSEVVNDV-------NLKTH----CGT--LIY--MAPEMLSQRQFDGKAVDIWAI
. . ...|| .  .||| .|. |||.   |. ...|. .|| |||||  . |          ...    .|   | .  |||| .  . |   . |.|. 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSF

GICIYAMVTRTF-PWKS-----TTDEELLHEIIQADIFFPNFV--------CPT-ISELLHGTLVKNPSERAPAAELISII
|.|.. . |.   |.        ...|... . | .   .           ||. . ..       .|..|   .|.....
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Pkinase_Tyr 87955.m00279.AA Pkinase_Tyr 1-72 26 6.9e-08 27.33 Pfam 83-158 (270) Show / Hide
Range on Protein: 1-72
Range on HMM: 83-158/270
Sequence Identity: 26% (20 aa)

MVIQEYCSGGEMFTKVRT----GPNIRESEIIRYSLQIISAINYLHTRNIMHRDIKLENIVLDNNGDAKIIDFGLS
... ||. .| . .  |.    ....  .... ...|| .. .||. .|. |||.   |. ...|. .|| ||||.
YIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA