Gene 82761.m00463 (T.vaginalis)

82761.m00463

Species: T.vaginalis
Alias: TvagK0582, 82761.m00463
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
82761.m00463.AA Protein None 373 None Fasta, JSON
82761.m00463.kin_dom Protein Kinase Domain None 314 None Fasta, JSON

Protein domain

Protein domains of 82761.m00463.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82761.m00463.AA CDK 13-326 30 7.5e-90 287.65 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-284/284
Sequence Identity: 30% (107 aa)

FDIVETVGKGAYGAVSKAKMKGTN-----QIVALKKVSRDQI---AMKNGFPENAMREIKILRALSQNENVVHLFKIESDLQT---------KDVYMVFE
....| .| |.|| | ||. | |.     |||||||.  ..      | |||  | |||..|. |  ..|.| |. .  . ..         . .|||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YCEFDLQGLIYQWFTSGKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNT-----IRMGDFGLAREFPK---EKDRISKESSPW
|.. || ...                   .|||..|.|. ...|||..| |||.||.|| .  . .     .  .||||||.|     ..   ... .. 
YMDHDLKKYMD------------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTH-

NVVTIWYRAPELCLGAKHYG--PEIDNWSLGCVLYEMIT---GKVLFKSPLDNGKENVVSQLKSIISKCGTF--DKWPEAQEYMFYEKNYKEALSSFHAE
.||| ||||||| ||.|||.  ..|| ||.||...||.|   .| ||    .        ||. |.  |||   | ||.  ..  |              
EVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSE------IDQLFKIFRICGTPTEDNWPGVTKLPDY--------------

ASSIRQYLEQVIPEEAKEAIPLMEGLLQVNPKERMSIREAFLHPFL
                     |....|. .|| |.|  .|  ||..
--------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 82761.m00463.AA CMGC 13-326 21 1.1e-89 294.79 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-513/513
Sequence Identity: 21% (112 aa)

FDIVETVGKGAYGAVSKAKM--------------KGTNQIVALKKVSR--DQIA-----MKNGFPENAMREIKILRALS---------------QNEN-V
..|.. .|.|.|| | |..               . ||.|||.||...  ...      .|.|||  | ||||||. |.               ...| .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VHLFKIESDLQTK---------------DVYMVFEYCEFDLQGLIYQWFT-----SGKLPQEFD-------------KYLK-YVKCYFRQILQVIY--FC
|.|. |  . ...               ..|.||||.. || ..|..  .      ..   |               ||.  ... |..|||. .   .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIR-YMYQILRGLKLKYC

HSRN--IYHRDIKPSNIYVKLDNT--------------------IRMGDFGLAREFPKEKDRIS----------------KESSPWNVVTIWYRAPELCL
||..  | |||.||.|| .  ...                    .. .|||||| . ...| .                  .    .||| ||||||. |
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GA---------KHYGPEIDNWSLGCVLYEMITG--------KVLFKSPLDNGKENV----------VSQLKSIISKCGTF-----------------DKW
|.         .||...|| ||.||...||.||        | ||.     |. ..          . ||. |.  .||.                 ..|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFP-----GHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEW

PEAQE-------------------YMFYEKNYKEALSSFHAEASSIRQYLEQVIPE--------------------------------EAKEAIPLMEGL
|.  .                   ..   .||..   .|        . |.  .|.                                . ..|| |....
PNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKM

LQVNPKERMSIREAFLHPFL
|| .|..|... .|  ||..
LQYDPDKRITAEQALQHPYF
Kinase 82761.m00463.AA S_TKc 13-326 26 3.7e-76 260.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-231/231
Sequence Identity: 26% (88 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMREIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEF---DLQGLIYQWF
..|....||||.| | |.. |.|..|||.|...           |...|||.||.   . .|.|.|. .  |   ...|||.|||.    ||  .| .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

TSGK---LPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAPELCLGAKHY
. |.   .|         ...|..||.. . .|||..| |||.||.|| .    .|  .||||||..               ..| ||.|||..    .|
RHGLRFPFP------E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GY

GP-EIDNWSLGCVLYEMITGKVLFKSPLDNGKENVVSQLKSIISKCGTFDKWPEAQEYMFYEKNYKEALSSFHAEASSIRQYLEQVIPEEAKEAIPLMEG
|. ..| ||.||.||||..|. .|             |.. .. |.|                                            .||. ....
GKCKCDWWSCGCILYEMLCGYPPFP------------QMQMMFKKIG-------------------------------------------SPEAKDFIRK

LLQVNPKERMSIREAFL-------HPFL
.||..|..|... ||.        ||..
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82761.m00463.AA CDC2 13-229 40 3.6e-73 224.06 In-house 1-209 (301) Show / Hide 
Range on Protein: 13-229
Range on HMM: 1-209/301
Sequence Identity: 40% (90 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMREIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEFDLQGLIY-QWFTS
.  .| .|.| || | |.| . |||||||||.  .|     |.|. |.||| .| .| . .|.| |. .      . .||||||...||  .   .  . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

GKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAPELCLGAKHYGPEID
 ..|...      || |. |||| . |||.| | |||.||.|| .  . .|. .|||||| |.  .. .  |    .||| ||||||. ||.|.|  ..|
KHMPPQL------VKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTE---HEVVTLWYRAPEILLGCKRYSTPVD

NWSLGCVLYEM---ITGKVLF
 ||.||...||   .| | ||
MWSIGCIFAEMFMDVTKKPLF
Kinase 82761.m00463.AA Pkinase 13-326 26 1.6e-68 238.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-293/293
Sequence Identity: 26% (89 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMR--EIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEF-----DLQGLI
. |....|.|..| | |.. |||..|||.|..... . ..  ..... |  ||.|.. | . .|.| |. .  |   ...|||.||||      ||  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSW--KDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYI

YQWFTSGKLPQEFDKYL----KYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTI----RMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAP
           . .. .    . .|.|..|||. ...|||..| |||.||.|| .. ...|    . .|||||. |       ...   . ..|.||.||
ST---------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAP

ELCLGAKHYGPEIDNWSLGCVLYEMITGKVLFKSPLDNGKENVVSQLKSIISKCGTFDKWPEAQE----YMFYEKNYKEALSSFHAEASSIRQYLEQVIP
|...|...|||..| ||.||.||||..|. .|.   . . .| ..|.. |  . |.  .... ..    | |  .  . .            . .. . .
EVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------------F-HWTF-H

EEAKEAIPLMEGLLQVNPKERMSIREAFLHPFL
.  .|.. .....|...||.| ...... ||..
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82761.m00463.AA CRK7 13-326 31 4e-58 198.97 In-house 1-343 (343) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-343/343
Sequence Identity: 31% (117 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQI-AMKNGFPENAMREIKILRALSQNENVVHLFKIESDL-------QTK-DVYMVFEYCEFDLQG
..... .| | || | ||| | |...||||||  |     | |||  | ||||||| | . .|.| |  |  |        ..|  .||||||   || |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQL-NHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMG

LIYQWFTSGKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPK-EKDRISKESSPWNVVTIWYRAPELCLG
|      |. . ..| .    .||...|.|  .  || .|. ||||| ||| .     . . |||||| . . || |.        |.| |||.||| ||
LL----ESKEM-HHFSH--QQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTN----RVITLWYRPPELLLG

AKHY--------------------------------------GPEIDNWSLGCVLYEMITGKVLFKSPLDNGKENVVSQLKSIISKCGT--FDKWPEAQE
...|                                      ||||| || || | |  |.| .|.       .|   || .|   ||.   . |||. .
EERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQG------NNEMAQLEKIYKICGSPNPNNWPEVMK

YMFYEKNYKEALSSFHAEASSIRQYLEQVIPEEA-----KEAIPLMEGLLQVNPKERMSIREAFLHPFL
  ...         .       | ..|...  .      ||.  |. ..|  .|| |..  |.  |...
LPWWNT--------MKPKRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 82761.m00463.AA CDK5 13-326 34 2.1e-57 179.71 In-house 1-287 (287) Show / Hide 
Range on Protein: 13-326
Range on HMM: 1-287/287
Sequence Identity: 34% (109 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMREIKILRALSQNENVVHLFK-IESDLQTKDVYMVFEYCEFDLQGLIYQWFTS
.. .| .| | || | ||. | |  |||||.|  |.     | |  |.||| .|. | . .|.| |.  | |.   |   .|||.|  ||   . .    
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDS--EDEGVPSTAIREICLLKEL-KHKNIVRLHDVIHSE---KKLTLVFEFCDQDLKKYMDSCNG-

GKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAPELCLGAKHYGPEID
     | |. .  .| .  | |. . |||.... ||| || |  .    . ...|||||| |       | |     ||| |||.|   .|.|||   ||
-----EMDMHI--IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHE-----VVTLWYRPPDVLMGSKHYSTSID

NWSLGCVLYEMI-TGKVLFKSPLDNGKENVVSQLKSIISKCGT--FDKWPEAQEYMFYEKNYKEALSSFHAEASSIRQYLEQVIPEEAKEAIPLMEGLLQ
 || ||.. ||. .|. ||         .|  ||| |    ||   ||||   .   | |   ... ...|. |     ..|..|.  ..   |....||
MWSCGCIFAEMANAGRPLFPG------NDVEDQLKRIFKIMGTPCEDKWPSITKLPDY-KPNHQQYPMYPAHQS-----WQQIVPKLDEKGMDLLQKMLQ

VNPKERMSIREAFLHPFL
.||..|.|  .|  ||. 
CNPNQRISAKAALHHPYF
Kinase 82761.m00463.AA CDK-DD1 13-229 36 9e-52 157.83 In-house 1-200 (379) Show / Hide 
Range on Protein: 13-229
Range on HMM: 1-200/379
Sequence Identity: 36% (80 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFP-ENAMREIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEFDLQGLIYQWFTS
. |.. .| | || | ||  |.|  .||||...   ..  .| | .    |.| |  |    |.|||  .    ..    ||||| |.|| ...      
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFK--DWNQEDGEPKV----ECKYLMQLRHCKNIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCY

GKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPK-EKDRISKESSPWNVVTIWYRAPELCLGAKHYGPEI
  ||.        .||.|.| |  |  ||.  | ||||||.|  .       ..|||..  . |      |      .||. |||.||| .|   |||||
MSLPC--------IKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSH-----QVVSLWYRPPELLMGSCQYGPEI

DNWSLGCVLYEMITGKVLF
| || ||.| ||||.  .|
DMWSVGCILMEMITNFYMF
Kinase 82761.m00463.AA ERK7 13-229 36 3.6e-49 166.16 In-house 1-207 (292) Show / Hide 
Range on Protein: 13-229
Range on HMM: 1-207/292
Sequence Identity: 36% (81 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKV---SRDQIAMKNGFPENAMREIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEFDLQGLIYQWF
..| . .|||||| | ||  | | |.|||||.    |.|.           ||| .|... . .|...|  .      .|.|.|||. | ||   | .  
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQ-----RTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRK--

TSGKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSPWN---VVTIWYRAPELCLGAKHY
  |.. ..  |     .. . |.|. | . || |. |||.||||| .  . .... ||||||   . ..   .|. |     | | ||||||  ||...|
--GNILKDIHK-----QYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY--DEQNPMLTEYVATRWYRAPEILLGSHRY

GPEIDNWSLGCVLYEMITGKVLF
 . .| ||.||.| ||..|| .|
TKGVDMWSIGCILGEMLRGKPMF
Kinase 82761.m00463.AA PITSLRE 13-230 37 8.4e-45 155.16 In-house 1-208 (295) Show / Hide 
Range on Protein: 13-230
Range on HMM: 1-208/295
Sequence Identity: 37% (83 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMREIK-ILRALSQNENVVHLFKIESDLQTKDVYMVFEYCEFDLQGLIYQWF--
| .. ... |.|| |..|| | |. |||||..  ..   | |||  ..|||. ||.|| | .|.| .  |        .|||.|| | || .|.      
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMAL-QHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRR

-TSGKLPQEFDKYLKYVKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAPELCLGAKHYGP
  . |...        .||   | |  . . |.  | ||| | ||.          .|||||||.      ...     .||| ||||||| ||.| | .
NQPFKPGE--------IKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTP-----CVVTLWYRAPELLLGCKKYST

EIDNWSLGCVLYEMITGKVLFK
 .| || ||.. |.||.|.||.
PVDMWSVGCIFAEFITMKPLFQ
Kinase 82761.m00463.AA MAPK 140-326 29 1.2e-39 134.62 In-house 134-328 (328) Show / Hide 
Range on Protein: 140-326
Range on HMM: 134-328/328
Sequence Identity: 29% (61 aa)

HSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKEKDRISKESSP---------WNVVTIWYRAPELCLG--AKHYGPEIDNWSLGCVLYEMIT-GKV
|| |. |||.||||| |  . . ...|||||| .  |.  . ..  |          .|.| ||||||. |.  ..||   .| ||.|| . ||.| .|.
HSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKP

LFKSPLDNGKENVVSQLKSIISKCGTFDKWPEAQEYMFYE--KNYKEALSSFHAEASSIRQYLEQVIPE----EAKEAIPLMEGLLQVNPKERMSIREAF
||.       .. . |.. |.. .||    |. . . . .  ..... ..|.       .. .|...|        .|| |.| .|. .|..| .. || 
LFP------GKDYIDQWNLIMEVLGT----PSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEAL

LHPFL
 ||..
QHPYF
Kinase 82761.m00463.AA CDKL 125-229 43 1e-31 105.68 In-house 100-200 (286) Show / Hide 
Range on Protein: 125-229
Range on HMM: 100-200/286
Sequence Identity: 43% (46 aa)

VKCYFRQILQVIYFCHSRNIYHRDIKPSNIYVK-LDNTIRMGDFGLAREFPKEKDRISKESSPWNVVTIWYRAPELCLGAKHYGPEIDNWSLGCVLYEMI
|. |  |||. | |||. |. |||||| ||..   . .. ..|||.||  ..... |  .     | | ||||||| .|   ||...| |..|||. |||
VRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTD----YVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMI

TGKVLF
.|  |.
DGQPLW
Kinase 82761.m00463.AA MAPK 13-107 29 9.7e-22 71.78 In-house 1-108 (328) Show / Hide 
Range on Protein: 13-107
Range on HMM: 1-108/328
Sequence Identity: 29% (33 aa)

FDIVETVGKGAYGAVSKAKMKG------TNQIVALKKVS---RDQIAMKNGFPENAMREIKILRALSQNENVVHLFKIESDL-----QT----KDVYMVF
..|.. .|.|||| | .|. |       ....||.||.|   .... .|      . ||||.|| . . ||.. |. |          .    .|.|.|.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-----RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVM

EYCEFDLQGLIYQ
|..| ||. .|..
ELMETDLHQIIKS
Kinase 82761.m00463.AA CDKL 13-98 42 5.3e-14 44.25 In-house 1-81 (286) Show / Hide 
Range on Protein: 13-98
Range on HMM: 1-81/286
Sequence Identity: 42% (37 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKK--VSRDQIAMKNGFPENAMREIKILRALSQNENVVHLFKIESDLQTKDVYMVFEYCE
...   || |.|| | | . | |.|||| ||   |.|. . |     .||||||.|. | . || | |  ||   . .  ..|||||.
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVK----KIAMREIKMLKQLKH-ENIVNL--IEVFRRKRKLHLVFEYCD
Kinase 82761.m00463.AA TyrKc 13-288 19 3.1e-11 -41.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-288
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

FDIVETVGKGAYGAVSKAKMKGTNQIVALKKVSRDQIAMKNGFPENAMREIKILRAL-SQNENVVHLFKIESD-----LQTKDVYMVFEYCEF-DLQGLI
    .. | ||.| | |...|   . || |..  |         |  |||..|.. |  ...|.| |. . ..     .  . ...|.||..  ||.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-YQWFTSGKLPQEFDKYLKYVKCYFRQILQVIYFC----------HSRNIYHRDIKPSNIYVKLDNTIRMGDFGLAREFPKE------KDRISKES--SP
 .   .                    .  . ..||          ||.|. |||.   |. |. ..|.. .||||.|.   .      || ..| .  . 
RKHRPK-------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGG

WNVVTIWYRAPELCLGAKHYGPEIDNWSLGCVLYEMIT-GKVLFKSPLDNGKENVVSQLKSIISKCGTFDKWPEAQEYM----FYEKNYKEALSSFHA--
  .. |   ||| |.  . . .. | || | ...|. | |.     .  .      ...   . . .  .. |.. . |      .. |.  ..  |.  
KTMLPIRWMAPE-CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDP

----EASSIRQYL
      | |....
EDRPTFSEIHECF
Kinase 82761.m00463.AA ERK7 285-326 38 4.1e-10 30.46 In-house 251-292 (292) Show / Hide 
Range on Protein: 285-326
Range on HMM: 251-292/292
Sequence Identity: 38% (16 aa)

RQYLEQVIPEEAKEAIPLMEGLLQVNPKERMSIREAFLHPFL
|. |.|..|.  ..|| |.  ||. |||.|... .|  ||. 
RKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 82761.m00463.AA CDC2 285-326 29 1.2e-08 22.12 In-house 251-301 (301) Show / Hide 
Range on Protein: 285-326
Range on HMM: 251-301/301
Sequence Identity: 29% (15 aa)

RQYLEQVIPE---------EAKEAIPLMEGLLQVNPKERMSIREAFLHPFL
.| |....|            .|.| | . .|| .|  | |..||  ||..
PQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 82761.m00463.AA Pkinase_Tyr 13-78 30 1e-06 23.09 Pfam 1-69 (270) Show / Hide 
Range on Protein: 13-78
Range on HMM: 1-69/270
Sequence Identity: 30% (22 aa)

FDIVETVGKGAYGAVSKAKMK----GTNQIVALKKVSRDQIAMK-NGFPENAMREIKILRALSQNENVVHL
  . .. |.||.| | |...|    .|.. || |.. ...   . | . |  |||.||.. | ...|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRL
Kinase 82761.m00463.AA CDKL 288-326 32 1e-06 18.46 In-house 247-286 (286) Show / Hide 
Range on Protein: 288-326
Range on HMM: 247-286/286
Sequence Identity: 32% (13 aa)

LEQVIPEEA-KEAIPLMEGLLQVNPKERMSIREAFLHPFL
||.  |.   |.|. .|...|. .| |||.  ..  ||. 
LEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 82761.m00463.AA CDK-DD1 300-326 37 6e-06 13.64 In-house 353-379 (379) Show / Hide 
Range on Protein: 300-326
Range on HMM: 353-379/379
Sequence Identity: 37% (10 aa)

IPLMEGLLQVNPKERMSIREAFLHPFL
. |.|..|  .|| |.. .||  ||. 
LDLIERMLTLCPKKRINTKEALQHPWF
Kinase 82761.m00463.AA PITSLRE 302-326 36 0.000506 10.78 In-house 271-295 (295) Show / Hide 
Range on Protein: 302-326
Range on HMM: 271-295/295
Sequence Identity: 36% (9 aa)

LMEGLLQVNPKERMSIREAFLHPFL
|. ..|  |||.|..  .|  ||. 
LLNQMLTYNPKNRITASDALKHPWF
Kinase 82761.m00463.AA Pkinase_Tyr 159-171 53 5.992044 0.45 Pfam 147-159 (270) Show / Hide 
Range on Protein: 159-171
Range on HMM: 147-159/270
Sequence Identity: 53% (7 aa)

DNTIRMGDFGLAR
.|... .||||||
NNVVKICDFGLAR