Gene 84511.m00300 (T.vaginalis)

84511.m00300

Species: T.vaginalis
Alias: TvagK0284, 84511.m00300
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84511.m00300.AA Protein None 1113 None Fasta, JSON
84511.m00300.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 84511.m00300.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84511.m00300.AA MLK 220-474 35 3.4e-88 299.3 In-house 1-291 (291) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-291/291
Sequence Identity: 35% (103 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSF-----ELFYREISIFTKINHPA----LLPFVGVTITH-P-FYIVTEFMEGGCLYN
......||.|.| .|.  .  |     ||||||. .|  |   |      . | .|. .. ...||       .|.|| . . . |.||.|..|||.|||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

RLHDREP-------------LRDPTKLTIIAIGVAHAMKYLHSHK---IIHRDLKSLNVLLDA------NDFPKVCDFGMSRIMPENGEMMSGSVGTVQW
 ||....               |.  .  .|  .|..| ||||..   |||||||| |.|.|.      ..  |.|||| || . .... | .  ||. |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEVL---RSERYSEKADVYSFGILLWELLTGDAPFK-QMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
|||||.   |.|.||||.||.|.|..|||.||.  |.|  .   ..   |   . || .|.. . ...||.| ||..|| |||.|  | . |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 84511.m00300.AA TKL 226-474 26 2.2e-85 290.0 In-house 1-364 (364) Show / Hide 
Range on Protein: 226-474
Range on HMM: 1-364/364
Sequence Identity: 26% (100 aa)

IGHGAFADVYWSYQINDKT------NNKIVAVKKLKAVH-------------------------FSQYSFELFYREISIFTKINHPALLPFVGVTITHP-
|| |.|. . .  . .  .       .| |||||.|  .                         ...  .. . .|| .  ...|| ...|.|. .  | 
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------FYIVTEFMEGGCLYNRLHDREPLRDPTKLTIIAIGVAHAMKYLHSHK--------IIHRDLKSLNVLLDAN--------------DF
             ..||.|...||.|...||       . ..  .|...| .| ||||..        |||||||| |.|.| |              ..
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKVCDFGMSRIMPENGE-------------------MMSGSVGTVQWMAPEVLRSE----------------RYSEKADVYSFGILLWELLTGDAPFKQM
.|.|||| || | ..|.                   . .  .|| .|||||||| .                 ||||.|||||||.|||.||.  |....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

RDVQVT---------LAVLSSNARPMMP------------PNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
   ..            | . . || .|            |.. ....||.. |||.||.||| |..| | |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 84511.m00300.AA Dicty4 220-476 38 5.8e-72 239.33 In-house 1-277 (277) Show / Hide 
Range on Protein: 220-476
Range on HMM: 1-277/277
Sequence Identity: 38% (108 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKL--KAVHFSQYSFELFYREISIFTKINHPALLPFVGVTIT---HP--FYIVTEFMEGGCLYNRLHD
 .  ..|| |.|. ||       .   |.||||||  . . |...  . | .|..|  || || .. | |  .    ||  . ||||.|  | ||. |||
INIEQRIGKGSFGEVYKG-----TWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD

------REPLRDPTKLTI---IAIGVAHAMKYLHS--HKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENG--EM-MSGSVGTVQWMAPEVLRSERYS
       .   | .  .    .|. .|  | .||.    |||||||| | | |.|   |||||| |..| .       ... .||. ||||||.....| 
KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

EKADVYSFGILLWELLTGDAPFK--QMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKM--LES
||||||||||.|||.||...|.    |  .|.  || .   || .|.........||. ||| || .|| || | .   ||.
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 84511.m00300.AA TyrKc 220-474 29 8.2e-71 242.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-280/280
Sequence Identity: 29% (86 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYREISIFTKI--NHPALLPFVGVTIT--------HPFYIVTEFMEGGCLYNR
  |.|..|.|||  ||    .        ||||.||. .      | |.||..| .|.  .|| .. ..|| ..        .| .||.|.|..|.| ..
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LHDREPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPEN------GEMMS-----GSV--GTVQWMAPEVLRSER
|....|   . .|  ... .|  | ||||...|||||   |.|...|   |..|||.||   .       ... .     |.     . |||||...  .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YSEKADVYSFGILLWELLT-GDAPFKQM----RDVQVTLAVLSSNARPMMPPN--------VSTRLAKLIKVCWDSDPDKRPDFETIAKML
...| ||.|||...||..| |. |   |     . |  .. . .  |.. |||         .. . ...| ||. ||..|| |..| . .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84511.m00300.AA Pkinase_Tyr 220-474 31 5e-70 237.79 Pfam 1-270 (270) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-270/270
Sequence Identity: 31% (87 aa)

FDLKKIIGHGAFADVYWSYQI-NDKTNNKIVAVKKLKAVHFSQYS--FELFYREISIFTKI-NHPALLPFVGVTI--THP--FYIVTEFMEGGCLYNRLH
  . | .|.||| .||  .    .. ..  ||||.||  . ..     | | ||..| ... .|| .. ..|| .    |   |||.|.|..|.|.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----REPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIM--PENG-EMMSGSVGTVQWMAPEVLRSERYSEKADVY
.    ..||  .. |  ... .| .| ||.|...|||||   |.|.. | . |.||||..| .   ..   . .|.   . |||||...  ....| ||.
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SFGILLWELLT-GDAP-FKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
|||.|.||..| |. | .. | . .|  ..  .. |  .|.| .  . .|.| ||. ||..|| |. |  .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 84511.m00300.AA HH498 220-474 31 1.2e-69 219.91 In-house 1-284 (284) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-284/284
Sequence Identity: 31% (92 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSF------ELFYREISIFTKINHPALLPFVGVTITHP--FYIVTEFMEGGCLYNRL-
.  ...|| |.| .||  .       |||||||  .|  |.  |         | ||.||  . |||    ||. ..  |  | |||.. ..| |. .| 
IEFHEKIGSGSFGKVYKGE-----WRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILN

-------------HDRE---PLRDPTKLTIIAIGVAHAMKYLHS---HKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGS-VGTVQWMAPE
             |         |.    .|.. ||| | |||.   | |||||| | |.|....   .| ||| ||   . ..    .  |   |||||
TIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPE

VLR-SERYSEKADVYSFGILLWELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPN----VSTRLAKLIKVCWDSDPDKRPDFETIAKML
|   . .||.|.||.|... .||..|.  ||     .     .     || .|      .  .   ||  ||.  |. ||||  |  .|
VFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 84511.m00300.AA TKL-Unique 245-474 32 2.4e-68 233.4 In-house 19-290 (290) Show / Hide 
Range on Protein: 245-474
Range on HMM: 19-290/290
Sequence Identity: 32% (89 aa)

NNKIVAVKKLKA-VHFSQYSFELFYREISIFTKIN-HPALLPFVGVTI----THP-FYIVTEFMEGGCLYNRLH---------DREPLRDPTKLTIIAIG
. ..||.|...    .|  . . |..|...  |.. || .. ..|...    . | ..||.|...|| ||. ||          ..   .. .   .|| 
RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAID

VAHAMKYLHSHK--IIHRDLKSLNVLLDAN-----DFPKVCDFGMSRIMP-ENGEMMSGS--------VGTVQWMAPEVLRS--ERYSEKADVYSFGILL
.| .| |||. .  ||||||||.|.|.| |        |.|||| |..   .| .  ...        .|. .||||||||.  . ||||.||||||| |
IAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL

WELLTGDA------PFKQMRDVQVTLAVLS--SNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
||..|..       |.. | . |.  .| .   | ||. |..   .. .||. ||..||..|| |..| . |
WEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 84511.m00300.AA LRRK 220-476 27 1.9e-63 217.12 In-house 1-351 (351) Show / Hide 
Range on Protein: 220-476
Range on HMM: 1-351/351
Sequence Identity: 27% (97 aa)

FDLKKIIGHGAFA-DVYWSYQIN---------------------DKTNNKI--VAVKKLKA--------------------------------VHFSQYS
.   . || |.|.  ||    ..                       . ..   ||.||..                                   ..  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FELFYREISIFTKINHPALLPFVGVTITHPFYIVTEFMEGGCLYNRLHDRE--PL-----R-DPTKLTIIAIGVAHAMKYLHSHK--IIHRDLKSLNVLL
| .| .|..|  . ||| ... .|..| ||. .|.|..  | || .||...  ..     . ... .  ||. .| .|.|||||.  |||||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DANDFP------------KVCDFGMSR-IMPENGEMMSGSVGTVQWMAPEVLR---SERYSEKADVYSFGILLWELLTGD-APFKQMR-------DVQVT
   . .            |..||| ||   .   .  .|.||. .|||||..|    | |.||.|.||||..||||||..  || ..          |. 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

LAVLSSNARPMMPPN-VST-----RLAKLIKVCWDSDPDKRPDFETIAKMLES
.... .  ||  |..         .. .||. ||. ||.||| |..| | |..
DKII-EGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 84511.m00300.AA Dicty4-Unclassified 220-474 34 5.8e-63 214.47 In-house 1-263 (263) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-263/263
Sequence Identity: 34% (94 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQY--SFELFYREISIFTKINHPALLPFVGVTITHP------FYIVTEFMEGGCLYNRLH
    . || |.|. |   .  | |   | |||||.    |.      . | .|. |   | || |.   |  |  |      . ||.|||  | |    |
IQIDQFIGKGHFSKV---HKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIH

-----DREPLR-DPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGSVG-TVQWMAPEVLRSERYSEKADVY
        |.. | |    .|. .|  | .||.  .||||.|| |.|.| .   |. |||.||    |  |    .. |. | .||.|. | |  |.|||
SKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMT--TIAGTPKWESPECLMHESYNQKSDVY

SFGILLWELLTGDAPFKQMR-DVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
|....|.||.||| |.      . .   | .   || .| |.   . |||| ||  || ||| .. | . |
SYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 84511.m00300.AA TK 220-474 17 9.3e-63 208.91 In-house 1-486 (486) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-486/486
Sequence Identity: 17% (85 aa)

FDLKKIIGHGAFA---DVY--WSYQINDKTNNK--------------------IVAVKKLKAVH-FSQYSFEL--------------FYREISIFT--KI
  | | .|.|.|    .||  . ...|.. ...                     |||| ||. .  ||  |..              . .|....   . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPALLPFVG-VTIT------------HPFYIVTEFMEGGC----LYNRLHDREPLRDPTKLTI------------------------------------
.|| .. ..| .|              .|..||.|.|..|.    | . |... | . .   ..                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAIGVAHAMKYLHSH------KIIHRDLKSLNVLLDANDF-----------PKVCDFGMS--
                                      ..  .| .| ||||.      ...||||   |.|.. |.             |..|||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RIMPENGEMMSGS-VGT-------------------------VQWMAPEVLRSE---------RYSEKADVYSFGILLWELLT-GDAPFKQMRD
      | ......  . |  ||                         . |||||.|..          ....| ||.|||.|.||..| |..|.  . .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

V---------QVTLAVLSSN--------------ARPMMPPNVS--------------TRLAKLIKVCWDSDPDKRPDFETIAKML
          |  .  | .                |.  ||. .              . .. |.. ||. ||..||.|... ..|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 84511.m00300.AA S_TKc 220-474 28 2.9e-61 210.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYREISIFTKINHPALLPFVGVTITHPFYIVTEFMEG--GCLYNRLHDREPL-
... ..||.|||. ||  . ..    ..|||.|..|         | ..|||.|  | .|| .  . .|  .. .|.|.|...|  | |. ....| .  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG

----RDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGSVGTVQWMAPEVLRSERYSE-KADVYSFGILLW
     ..     ..  .. |..|.|||.|||||||  |.|||     |.||||..|..       .  .||  .||||||    |.  |.|..|.|..|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAK---------ML
|.|.|  ||    ..|... ..            |  .  .|. |.. ||.|||    . .          .
EMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84511.m00300.AA Dicty5 267-478 38 1.6e-57 196.58 In-house 43-260 (260) Show / Hide 
Range on Protein: 267-478
Range on HMM: 43-260/260
Sequence Identity: 38% (85 aa)

FYREISIFTKIN--HPALLPFVGVTITHPFY--IVTEFMEGGCLYNRLHD-RE----PLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDAND
||||. |   .   || .  . |       |  .|||.   | | | | | |     |.  ...|  .||..| .|..|||  ||||||||.|.|.  | 
FYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENW

FPKVCDFGMSRIMPENGEMMSGSVGTVQWMAPEVLRSERYSEKADVYSFGILLWELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCW
  |. ||| ||   .|   |   |||  |||.|.  .  | .|.||||||| |||..| . |.. .      . | .   || .|. . |  ..||| ||
KIKIIDFGTSRFV-DNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCW

DSDPDKRPDFETIAKMLESGE
   | .|| |  | |..||  
QQKPHNRPSFKEICKYFESII
Kinase 84511.m00300.AA UTK 220-474 29 2.5e-57 194.69 In-house 1-296 (296) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-296/296
Sequence Identity: 29% (88 aa)

FDLKKIIGHGAFADVYW-SY-QINDKTNNKIVAVKKLKAVHFSQYSFE---LFYREIS---IFTKIN-HPALLPFVGV-TITHPFYIVTEFMEGGCLYN-
  | . .|.||| .|.  .. |...     .||||.... ...| . |    | .|     .  . . || .| .||| |   |..||||.||.| | . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

--RLHD----REPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDAN-------DFPKVCDFG---MSRIMP---------ENGEMMSGSVGT
  | ..    .. . . ....  |  .|..| ||||....||||   |.|....        . |..|||   ||| ..         |  . |. ... 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

--VQWMAPEVLRSE-RYSEKADVYSFGILLWELLT-GDAPFKQMRDVQVTLAVLSSN-ARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML
  ..|||||.| .  |...| ||.|||...||..| | .|.. | ..||...|.  . .|.  |. .. .. .| . || .||..|||||.. . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase 84511.m00300.AA Pkinase 220-474 28 4.6e-56 197.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 220-474
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYR--EISIFTKINHPALLPFVGVTITHP-FYIVTEFMEGG----CLYNRLH-
. ....|| |.|. |   |.  .| ..||||||..| .| .    .   |  ||.|  ..|||  . . ..  ...  |.|.|..|||     |. ... 
YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

DREPLR--DPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFP----KVCDFGMSRIM-PENGEMMSGSVGTVQWMAPEVLR-SERYSEKADV
.|.     ..  .  ..  .. ...|.||..|||||||. |.|.| |. .    |.|||| .. .   |.. |.. .||  .|||||.| .. |. |.|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGILLWELLTGDAPFKQM-----RDVQVTLAVLSSNARPMMPP--------------------NVSTRLAKLIKVCWDSDPDKRPDFETIAKM--L
.|.|..|.|.|.|  ||..      .| .. ..   .   .   |                    |.|  . ..|| |.. || ||| .| | .   .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84511.m00300.AA TKL 1103-1113 54 0.054853 2.96 In-house 354-364 (364) Show / Hide 
Range on Protein: 1103-1113
Range on HMM: 354-364/364
Sequence Identity: 54% (6 aa)

RPTMLSILSRL
||... ||.||
RPSFQEILKRL
Kinase 84511.m00300.AA TKL-Unique 1102-1113 41 0.150734 1.45 In-house 279-290 (290) Show / Hide 
Range on Protein: 1102-1113
Range on HMM: 279-290/290
Sequence Identity: 41% (5 aa)

IRPTMLSILSRL
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QRPSFDEIIHRL