Gene 84511.m00300 (T.vaginalis)
84511.m00300
Species: T.vaginalis
Alias: TvagK0284, 84511.m00300
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
84511.m00300.AA | Protein | None | 1113 | None | Fasta, JSON |
84511.m00300.kin_dom | Protein Kinase Domain | None | 254 | None | Fasta, JSON |
Protein domains of 84511.m00300.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 84511.m00300.AA | MLK | 220-474 | 35 | 3.4e-88 | 299.3 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-291/291 Sequence Identity: 35% (103 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSF-----ELFYREISIFTKINHPA----LLPFVGVTITH-P-FYIVTEFMEGGCLYN ......||.|.| .|. . | ||||||. .| | | . | .|. .. ...|| .|.|| . . . |.||.|..|||.||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN RLHDREP-------------LRDPTKLTIIAIGVAHAMKYLHSHK---IIHRDLKSLNVLLDA------NDFPKVCDFGMSRIMPENGEMMSGSVGTVQW ||.... |. . .| .|..| ||||.. |||||||| |.|.|. .. |.|||| || . .... | . ||. | VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW MAPEVL---RSERYSEKADVYSFGILLWELLTGDAPFK-QMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML |||||. |.|.||||.||.|.|..|||.||. |.| . .. | . || .|.. . ...||.| ||..|| |||.| | . | MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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Kinase | 84511.m00300.AA | TKL | 226-474 | 26 | 2.2e-85 | 290.0 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 226-474 Range on HMM: 1-364/364 Sequence Identity: 26% (100 aa) IGHGAFADVYWSYQINDKT------NNKIVAVKKLKAVH-------------------------FSQYSFELFYREISIFTKINHPALLPFVGVTITHP- || |.|. . . . . . .| |||||.| . ... .. . .|| . ...|| ...|.|. . | IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC -------------FYIVTEFMEGGCLYNRLHDREPLRDPTKLTIIAIGVAHAMKYLHSHK--------IIHRDLKSLNVLLDAN--------------DF ..||.|...||.|...|| . .. .|...| .| ||||.. |||||||| |.|.| | .. GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC PKVCDFGMSRIMPENGE-------------------MMSGSVGTVQWMAPEVLRSE----------------RYSEKADVYSFGILLWELLTGDAPFKQM .|.|||| || | ..|. . . .|| .|||||||| . ||||.|||||||.|||.||. |.... CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY RDVQVT---------LAVLSSNARPMMP------------PNVSTRLAKLIKVCWDSDPDKRPDFETIAKML .. | . . || .| |.. ....||.. |||.||.||| |..| | | PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 84511.m00300.AA | Dicty4 | 220-476 | 38 | 5.8e-72 | 239.33 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 220-476 Range on HMM: 1-277/277 Sequence Identity: 38% (108 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKL--KAVHFSQYSFELFYREISIFTKINHPALLPFVGVTIT---HP--FYIVTEFMEGGCLYNRLHD . ..|| |.|. || . |.|||||| . . |... . | .|..| || || .. | | . || . ||||.| | ||. ||| INIEQRIGKGSFGEVYKG-----TWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD ------REPLRDPTKLTI---IAIGVAHAMKYLHS--HKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENG--EM-MSGSVGTVQWMAPEVLRSERYS . | . . .|. .| | .||. |||||||| | | |.| |||||| |..| . ... .||. ||||||.....| KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN EKADVYSFGILLWELLTGDAPFK--QMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKM--LES ||||||||||.|||.||...|. | .|. || . || .|.........||. ||| || .|| || | . ||. EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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Kinase | 84511.m00300.AA | TyrKc | 220-474 | 29 | 8.2e-71 | 242.48 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-280/280 Sequence Identity: 29% (86 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYREISIFTKI--NHPALLPFVGVTIT--------HPFYIVTEFMEGGCLYNR |.|..|.||| || . ||||.||. . | |.||..| .|. .|| .. ..|| .. .| .||.|.|..|.| .. ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY LHDREPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPEN------GEMMS-----GSV--GTVQWMAPEVLRSER |....| . .| ... .| | ||||...||||| |.|...| |..|||.|| . ... . |. . |||||... . LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YSEKADVYSFGILLWELLT-GDAPFKQM----RDVQVTLAVLSSNARPMMPPN--------VSTRLAKLIKVCWDSDPDKRPDFETIAKML ...| ||.|||...||..| |. | | . | .. . . |.. ||| .. . ...| ||. ||..|| |..| . . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 84511.m00300.AA | Pkinase_Tyr | 220-474 | 31 | 5e-70 | 237.79 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-270/270 Sequence Identity: 31% (87 aa) FDLKKIIGHGAFADVYWSYQI-NDKTNNKIVAVKKLKAVHFSQYS--FELFYREISIFTKI-NHPALLPFVGVTI--THP--FYIVTEFMEGGCLYNRLH . | .|.||| .|| . .. .. ||||.|| . .. | | ||..| ... .|| .. ..|| . | |||.|.|..|.|.. |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR D----REPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIM--PENG-EMMSGSVGTVQWMAPEVLRSERYSEKADVY . ..|| .. | ... .| .| ||.|...||||| |.|.. | . |.||||..| . .. . .|. . |||||... ....| ||. KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW SFGILLWELLT-GDAP-FKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML |||.|.||..| |. | .. | . .| .. .. | .|.| . . .|.| ||. ||..|| |. | .| SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | 84511.m00300.AA | HH498 | 220-474 | 31 | 1.2e-69 | 219.91 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-284/284 Sequence Identity: 31% (92 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSF------ELFYREISIFTKINHPALLPFVGVTITHP--FYIVTEFMEGGCLYNRL- . ...|| |.| .|| . ||||||| .| |. | | ||.|| . ||| ||. .. | | |||.. ..| |. .| IEFHEKIGSGSFGKVYKGE-----WRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILN -------------HDRE---PLRDPTKLTIIAIGVAHAMKYLHS---HKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGS-VGTVQWMAPE | |. .|.. ||| | |||. | |||||| | |.|.... .| ||| || . .. . | ||||| TIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPE VLR-SERYSEKADVYSFGILLWELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPN----VSTRLAKLIKVCWDSDPDKRPDFETIAKML | . .||.|.||.|... .||..|. || . . || .| . . || ||. |. |||| | .| VFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL |
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Kinase | 84511.m00300.AA | TKL-Unique | 245-474 | 32 | 2.4e-68 | 233.4 | In-house | 19-290 (290) | Show / Hide |
Range on Protein: 245-474 Range on HMM: 19-290/290 Sequence Identity: 32% (89 aa) NNKIVAVKKLKA-VHFSQYSFELFYREISIFTKIN-HPALLPFVGVTI----THP-FYIVTEFMEGGCLYNRLH---------DREPLRDPTKLTIIAIG . ..||.|... .| . . |..|... |.. || .. ..|... . | ..||.|...|| ||. || .. .. . .|| RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAID VAHAMKYLHSHK--IIHRDLKSLNVLLDAN-----DFPKVCDFGMSRIMP-ENGEMMSGS--------VGTVQWMAPEVLRS--ERYSEKADVYSFGILL .| .| |||. . ||||||||.|.|.| | |.|||| |.. .| . ... .|. .||||||||. . ||||.||||||| | IAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL WELLTGDA------PFKQMRDVQVTLAVLS--SNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML ||..|.. |.. | . |. .| . | ||. |.. .. .||. ||..||..|| |..| . | WEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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Kinase | 84511.m00300.AA | LRRK | 220-476 | 27 | 1.9e-63 | 217.12 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 220-476 Range on HMM: 1-351/351 Sequence Identity: 27% (97 aa) FDLKKIIGHGAFA-DVYWSYQIN---------------------DKTNNKI--VAVKKLKA--------------------------------VHFSQYS . . || |.|. || .. . .. ||.||.. .. . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA FELFYREISIFTKINHPALLPFVGVTITHPFYIVTEFMEGGCLYNRLHDRE--PL-----R-DPTKLTIIAIGVAHAMKYLHSHK--IIHRDLKSLNVLL | .| .|..| . ||| ... .|..| ||. .|.|.. | || .||... .. . ... . ||. .| .|.|||||. |||||||| |.|| FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL DANDFP------------KVCDFGMSR-IMPENGEMMSGSVGTVQWMAPEVLR---SERYSEKADVYSFGILLWELLTGD-APFKQMR-------DVQVT . . |..||| || . . .|.||. .|||||..| | |.||.|.||||..||||||.. || .. |. WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE LAVLSSNARPMMPPN-VST-----RLAKLIKVCWDSDPDKRPDFETIAKMLES .... . || |.. .. .||. ||. ||.||| |..| | |.. DKII-EGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | 84511.m00300.AA | Dicty4-Unclassified | 220-474 | 34 | 5.8e-63 | 214.47 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-263/263 Sequence Identity: 34% (94 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQY--SFELFYREISIFTKINHPALLPFVGVTITHP------FYIVTEFMEGGCLYNRLH . || |.|. | . | | | |||||. |. . | .|. | | || |. | | | . ||.||| | | | IQIDQFIGKGHFSKV---HKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIH -----DREPLR-DPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGSVG-TVQWMAPEVLRSERYSEKADVY |.. | | .|. .| | .||. .||||.|| |.|.| . |. |||.|| | | .. |. | .||.|. | | |.||| SKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMT--TIAGTPKWESPECLMHESYNQKSDVY SFGILLWELLTGDAPFKQMR-DVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML |....|.||.||| |. . . | . || .| |. . |||| || || ||| .. | . | SYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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Kinase | 84511.m00300.AA | TK | 220-474 | 17 | 9.3e-63 | 208.91 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-486/486 Sequence Identity: 17% (85 aa) FDLKKIIGHGAFA---DVY--WSYQINDKTNNK--------------------IVAVKKLKAVH-FSQYSFEL--------------FYREISIFT--KI | | .|.|.| .|| . ...|.. ... |||| ||. . || |.. . .|.... . ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG NHPALLPFVG-VTIT------------HPFYIVTEFMEGGC----LYNRLHDREPLRDPTKLTI------------------------------------ .|| .. ..| .| .|..||.|.|..|. | . |... | . . .. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY --------------------------------------IAIGVAHAMKYLHSH------KIIHRDLKSLNVLLDANDF-----------PKVCDFGMS-- .. .| .| ||||. ...|||| |.|.. |. |..|||.| DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ ------RIMPENGEMMSGS-VGT-------------------------VQWMAPEVLRSE---------RYSEKADVYSFGILLWELLT-GDAPFKQMRD | ...... . | || . |||||.|.. ....| ||.|||.|.||..| |..|. . . GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS V---------QVTLAVLSSN--------------ARPMMPPNVS--------------TRLAKLIKVCWDSDPDKRPDFETIAKML | . | . |. ||. . . .. |.. ||. ||..||.|... ..| NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | 84511.m00300.AA | S_TKc | 220-474 | 28 | 2.9e-61 | 210.78 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-231/231 Sequence Identity: 28% (78 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYREISIFTKINHPALLPFVGVTITHPFYIVTEFMEG--GCLYNRLHDREPL- ... ..||.|||. || . .. ..|||.|..| | ..|||.| | .|| . . .| .. .|.|.|...| | |. ....| . YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG ----RDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFPKVCDFGMSRIMPENGEMMSGSVGTVQWMAPEVLRSERYSE-KADVYSFGILLW .. .. .. |..|.|||.||||||| |.||| |.||||..|.. . .|| .|||||| |. |.|..|.|..|. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY ELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAK---------ML |.|.| || ..|... .. | . .|. |.. ||.||| . . . EMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 84511.m00300.AA | Dicty5 | 267-478 | 38 | 1.6e-57 | 196.58 | In-house | 43-260 (260) | Show / Hide |
Range on Protein: 267-478 Range on HMM: 43-260/260 Sequence Identity: 38% (85 aa) FYREISIFTKIN--HPALLPFVGVTITHPFY--IVTEFMEGGCLYNRLHD-RE----PLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDAND ||||. | . || . . | | .|||. | | | | | | |. ...| .||..| .|..||| ||||||||.|.|. | FYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLITENW FPKVCDFGMSRIMPENGEMMSGSVGTVQWMAPEVLRSERYSEKADVYSFGILLWELLTGDAPFKQMRDVQVTLAVLSSNARPMMPPNVSTRLAKLIKVCW |. ||| || .| | ||| |||.|. . | .|.||||||| |||..| . |.. . . | . || .|. . | ..||| || KIKIIDFGTSRFV-DNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCW DSDPDKRPDFETIAKMLESGE | .|| | | |..|| QQKPHNRPSFKEICKYFESII |
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Kinase | 84511.m00300.AA | UTK | 220-474 | 29 | 2.5e-57 | 194.69 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-296/296 Sequence Identity: 29% (88 aa) FDLKKIIGHGAFADVYW-SY-QINDKTNNKIVAVKKLKAVHFSQYSFE---LFYREIS---IFTKIN-HPALLPFVGV-TITHPFYIVTEFMEGGCLYN- | . .|.||| .|. .. |... .||||.... ...| . | | .| . . . || .| .||| | |..||||.||.| | . VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY --RLHD----REPLRDPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDAN-------DFPKVCDFG---MSRIMP---------ENGEMMSGSVGT | .. .. . . .... | .|..| ||||....|||| |.|.... . |..||| ||| .. | . |. ... LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR --VQWMAPEVLRSE-RYSEKADVYSFGILLWELLT-GDAPFKQMRDVQVTLAVLSSN-ARPMMPPNVSTRLAKLIKVCWDSDPDKRPDFETIAKML ..|||||.| . |...| ||.|||...||..| | .|.. | ..||...|. . .|. |. .. .. .| . || .||..|||||.. . . WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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Kinase | 84511.m00300.AA | Pkinase | 220-474 | 28 | 4.6e-56 | 197.36 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 220-474 Range on HMM: 1-293/293 Sequence Identity: 28% (84 aa) FDLKKIIGHGAFADVYWSYQINDKTNNKIVAVKKLKAVHFSQYSFELFYR--EISIFTKINHPALLPFVGVTITHP-FYIVTEFMEGG----CLYNRLH- . ....|| |.|. | |. .| ..||||||..| .| . . | ||.| ..||| . . .. ... |.|.|..||| |. ... YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST DREPLR--DPTKLTIIAIGVAHAMKYLHSHKIIHRDLKSLNVLLDANDFP----KVCDFGMSRIM-PENGEMMSGSVGTVQWMAPEVLR-SERYSEKADV .|. .. . .. .. ...|.||..|||||||. |.|.| |. . |.|||| .. . |.. |.. .|| .|||||.| .. |. |.|. WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM YSFGILLWELLTGDAPFKQM-----RDVQVTLAVLSSNARPMMPP--------------------NVSTRLAKLIKVCWDSDPDKRPDFETIAKM--L .|.|..|.|.|.| ||.. .| .. .. . . | |.| . ..|| |.. || ||| .| | . . WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 84511.m00300.AA | TKL | 1103-1113 | 54 | 0.054853 | 2.96 | In-house | 354-364 (364) | Show / Hide |
Range on Protein: 1103-1113 Range on HMM: 354-364/364 Sequence Identity: 54% (6 aa) RPTMLSILSRL ||... ||.|| RPSFQEILKRL |
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Kinase | 84511.m00300.AA | TKL-Unique | 1102-1113 | 41 | 0.150734 | 1.45 | In-house | 279-290 (290) | Show / Hide |
Range on Protein: 1102-1113 Range on HMM: 279-290/290 Sequence Identity: 41% (5 aa) IRPTMLSILSRL .||. .|..|| QRPSFDEIIHRL |