94179.m00345

Species: T.vaginalis
Alias: 94179.m00345, TvagK0336
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94179.m00345.AA Protein None 1108 None Fasta, JSON
94179.m00345.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of 94179.m00345.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94179.m00345.AA MLK 220-473 34 8.1e-89 301.37 In-house 1-291 (291) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-291/291
Sequence Identity: 34% (102 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRI-----VAVKKMKAAHFTQYSL-----EMFMREITIFSKMNHPA----ILPFVGVTITP-P-FYIVTEFMEG
......||.|.| .|.     . .. |..     ||||. .|  |   |      . | .|. ......||     | .|.|| . | . |.||.|..||
IQFHEWIGSGSFGKVW-----KGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEG

GCLYNRLHDNQP-------------LRDPTKLTIIAIGVAHAMKYLHSQG---IVHRDLKSLNVLLDA------NDFPKVCDFGMSRTLPENGELMSGSV
|.||| ||....               |.  .  .|  .|..| ||||.    |.|||||| |.|.|.      ..  |.|||| || . .... | .  
GSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNA

GTVQWMAPEVL---KSERYTEKADVYSYGVLLWELLTGDSPFK-KMRDVQVTIAVLSSNARPMMPPN-PSRISKLIKICWDTDPDKRPDFETIAKIL
||. ||||||.   ..|.|.||.||.|.||.|||.||.  |.|  .   .. . |   . || .|.. | ...||.|.||..|| |||.|  | ..|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 94179.m00345.AA TKL 226-473 26 7.4e-83 281.58 In-house 1-364 (364) Show / Hide
Range on Protein: 226-473
Range on HMM: 1-364/364
Sequence Identity: 26% (98 aa)

IGHGAFADVYWSYQVSDNMNN----------RIVAVKKMKAAH-------------------------FTQYSLEMFMREITIFSKMNHPAILPFVGVTI
|| |.|. ||       . ..          . |||||.|  .                         ...   . . .|| . |. .|| |..|.|. .
IGSGGFGEVY-----KGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCC

TPP--------------FYIVTEFMEGGCLYNRLHDNQPLRDPTKLTIIAIGVAHAMKYLHSQG--------IVHRDLKSLNVLLDAN------------
 ||              ..||.|...||.|...||       . ..  .|...| .| ||||..        |.|||||| |.|.| |            
CPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

--DFPKVCDFGMSRTLPENGE-------------------LMSGSVGTVQWMAPEVLKSE----------------RYTEKADVYSYGVLLWELLTGDSP
  ...|.|||| ||.. ..|.                     .  .|| .|||||||. .                 |.||.||||.|..|||.||.  |
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

FKKMRDVQVT---------IAVLSSNARPMMPPNPSR-------------ISKLIKICWDTDPDKRPDFETIAKIL
....   ..          . | . . || .|| ...             ..||.. |||.||.||| |..| |.|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 94179.m00345.AA TyrKc 220-473 30 1.7e-74 254.7 SMART 1-280 (280) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-280/280
Sequence Identity: 30% (89 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKMKAAHFTQYSLEMFMREITIFSKM--NHPAILPFVGVTIT--------PPFYIVTEFMEGGCLYNR
  |.|..|.|||  ||           . ||||..|. .     .|.||||. | .|   .|| |. ..|| ..        .| .||.|.|..|.| ..
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LHDNQPLRDPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLDANDFPKVCDFGMSRTLPEN------GELMS-----GSV--GTVQWMAPEVLKSER
|....|   . .|  ... .|  | ||||....||||   |.|...|   |..|||.|| . .       ..  .     |.     . |||||...  .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTEKADVYSYGVLLWELLT-GDSPFKKM----RDVQVTIAVLSSNARPMMPPN---------PSRISKLIKICWDTDPDKRPDFETIAKIL
.|.| ||.|.||..||..| |..|   |     . |  |. . .  |.. |||         |. . ...| ||. ||..|| |..| ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 94179.m00345.AA HH498 220-473 31 1.9e-72 228.9 In-house 1-284 (284) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-284/284
Sequence Identity: 31% (92 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKMKAAHFTQYSL------EMFMREITIFSKMNHPAILPFVGVTITPP--FYIVTEFMEGGCLYNRL-
.  .. || |.| .||  .       | |||||  .|  |   |        || ||. | .. |||    ||. ..  |  | |||.. ..| |. .| 
IEFHEKIGSGSFGKVYKGE-----WRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILN

-------------HDNQ---PLRDPTKLTIIAIGVAHAMKYLHS---QGIVHRDLKSLNVLLDANDFPKVCDFGMSRTLPENGELMSGS-VGTVQWMAPE
             | ..      |.    .|.. ||| | |||.   . |.|||| | |.|....   .| ||| || . . ..    .  |   |||||
TIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPE

VLK-SERYTEKADVYSYGVLLWELLTGDSPFKKMRDVQVTIAVLSSNARPMMPPN-----PSRISKLIKICWDTDPDKRPDFETIAKIL
| . . .|..|.||.||.  .||..|.  ||     .     .     || .|       | ..| || .||.  |. ||||  |  ||
VFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL

Kinase 94179.m00345.AA Pkinase_Tyr 220-473 32 5e-70 237.78 Pfam 1-270 (270) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-270/270
Sequence Identity: 32% (90 aa)

FDLKKVIGHGAFADVYWSYQV-SDNMNNRIVAVKKMKAAHFTQYS--LEMFMREITIFSKM-NHPAILPFVGVTI--TPP--FYIVTEFMEGGCLYNRLH
  . |..|.||| .||  .   ..  ..  ||||..|  . ..    .|.||||. | ... .|| |. ..|| .    |   |||.|.|..|.|.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----NQPLRDPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLDANDFPKVCDFGMSRTLPENGEL---MSGSVGTVQWMAPEVLKSERYTEKADVY
.    .|||  .. |  ... .| .| ||.|....||||   |.|.. | . |.||||..|.. . ..     .|.   . |||||...  ..|.| ||.
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGVLLWELLT-GDSP-FKKMRDVQVTIAVL-SSNARPMMPPN-PSRISKLIKICWDTDPDKRPDFETIAKIL
|.|||.||..| |..| .. | . .  .. .  .. |  .|.| |  | .|.| ||. ||..|| |. |  .|
SFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 94179.m00345.AA Dicty4 220-475 36 2.9e-67 223.43 In-house 1-277 (277) Show / Hide
Range on Protein: 220-475
Range on HMM: 1-277/277
Sequence Identity: 36% (103 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKM--KAAHFTQYSLEMFMREITIFSKMNHPAILPFVGVTI----TP-PFYIVTEFMEGGCLYNRLHD
 .  . || |.|. ||       .    .|||||.  .   | .. |. | .|..| .|  || |. | |  .    .|  . ||||.|  | ||. |||
INIEQRIGKGSFGEVYKG-----TWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD

-----NQPLRDP-TKLTI---IAIGVAHAMKYLHS--QGIVHRDLKSLNVLLDANDFPKVCDFGMSR---TLPENGELMSGSVGTVQWMAPEVLKSERYT
      |    . .  .    .|. .|  | .||.    |.|||||| | | |.|   |||||| |.   .  ...  ... .||. ||||||. ...|.
KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

EKADVYSYGVLLWELLTGDSPFK--KMRDVQVTIAVLSSNARPMMPPN-PSRISKLIKICWDTDPDKRPDFETIAKI--LES
|||||||.| .|||.||.. |.    |  .|. .|| .   || .|.. | ....||. |||.|| .|| || | ..  ||.
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 94179.m00345.AA TKL-Unique 248-473 32 4.2e-67 229.24 In-house 22-290 (290) Show / Hide
Range on Protein: 248-473
Range on HMM: 22-290/290
Sequence Identity: 32% (87 aa)

IVAVKKMKA-AHFTQYSLEMFMREITIFSKMN-HPAILPFVGVTI----TPP-FYIVTEFMEGGCLYNRLH---------DNQPLRDPTKLTIIAIGVAH
.||.|. .  . .   ... | .|... .| . || |. ..|...    .|| ..||.|...|| ||. ||          |    .. .   .|| .| 
PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQ

AMKYLHSQG--IVHRDLKSLNVLLDAN-----DFPKVCDFGMSRTLP-ENGELMSGS--------VGTVQWMAPEVLKS--ERYTEKADVYSYGVLLWEL
.| |||. .  | ||||||.|.|.| |        |.|||| |...  .| .  ...        .|. .|||||||..  . |.||.||||.|. |||.
GMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI

LTGDS------PFKKMRDVQVTIAVLS--SNARPMMPPN-PSRISKLIKICWDTDPDKRPDFETIAKIL
.|..       |...| . |.  .| .   | ||. |.. | ....||. ||. ||..|| |..| . |
ATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 94179.m00345.AA TK 220-473 17 3.5e-64 213.79 In-house 1-486 (486) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-486/486
Sequence Identity: 17% (86 aa)

FDLKKVIGHGAFA---DVYWSYQVSDN----------------------MNNRIVAVKKMK---AAHFTQYSLEM------------FMREITIFS--KM
  | |..|.|.|    .||     ..|                      ...  |||| .|   |.. ..  .|.            ...|. ...  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPAILPFVG-VTIT------------PPFYIVTEFMEGGC----LYNRLHDNQPLRDPTKLTI------------------------------------
.|| |. ..| .|              .|..||.|.|..|.    | . |... | . .   ..                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAIGVAHAMKYLHSQ------GIVHRDLKSLNVLLDANDF-----------PKVCDFGMS--
                                      ..  .| .| ||||.      ..|||||   |.|.. |.             |..|||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RTLPENGELMSGS-VGT-------------------------VQWMAPEVLKSE---------RYTEKADVYSYGVLLWELLT-GDSPFKKMRD
      | ......  . |  ||                         . |||||.|..          ..|.| ||.|.|||.||..| |. |.  . .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

V---------QVTIAVLSS---------------NARPMMPPNP--------------SRISKLIKICWDTDPDKRPDFETIAKIL
          |  .  | .               . .|  |  |                .  |.. ||. ||..||.|... . |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 94179.m00345.AA LRRK 220-475 28 6.4e-64 218.66 In-house 1-351 (351) Show / Hide
Range on Protein: 220-475
Range on HMM: 1-351/351
Sequence Identity: 28% (100 aa)

FDLKKVIGHGAFA-DVY---WS------------------YQVSDNMNNRI--VAVKKMKA--------------------------------AHFTQYS
.   . || |.|.  ||   |                   ||   |  ..   ||.||..                                 . ..  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LEMFMREITIFSKMNHPAILPFVGVTITPPFYIVTEFMEGGCLYNRLHDNQ--PL-----R-DPTKLTIIAIGVAHAMKYLHSQG--IVHRDLKSLNVLL
.  | .|..| |..||| |.. .|..|  |. .|.|..  | || .||...  ..     . ... .  ||. .| .|.||||.   |.|||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DANDFP------------KVCDFGMSR--TLPENGELMSGSVGTVQWMAPEVLK---SERYTEKADVYSYGVLLWELLTGD-SPFKKMR--D----VQVT
   . .            |..||| ||  .   .| . .|.||. .|||||...    | ||||.|.||.|..||||||..  ||  .   |        
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG-VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

IAVLSSNARPMMP---PNPS----RISKLIKICWDTDPDKRPDFETIAKILES
    ..  ||  |    .|     . ..||. ||..||.||| |..| |.|..
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 94179.m00345.AA Dicty4-Unclassified 220-473 33 1.4e-63 216.64 In-house 1-263 (263) Show / Hide
Range on Protein: 220-473
Range on HMM: 1-263/263
Sequence Identity: 33% (91 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKMKAAHFTQY--SLEMFMREITIFSKMNHPAILPFVGVTITP-----PFYIVTEFMEGGCLYNRLH-
    . || |.|. |.       |   . |||||.    |      .. | .|. |   . ||  .   |  | |      . ||.|||  | |    | 
IQIDQFIGKGHFSKVHKG-----NWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHS

----DNQPLR-DPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLDANDFPKVCDFGMSRTLPENGELMSGSVGTVQWMAPEVLKSERYTEKADVYSY
     .||.. | |    .|. .|  | .||.  ..|||.|| |.|.| .   |. |||.||   ..   |    ||. | .||.|. | |. |.|||||
KPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVI-DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GVLLWELLTGDSPFKKMR-DVQVTIAVLSSNARPMMPPN-PSRISKLIKICWDTDPDKRPDFETIAKIL
...|.||.||| |.      . . . | .   || .| | .  ..|||| ||  || ||| .. | . |
AMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 94179.m00345.AA S_TKc 220-472 29 3.9e-62 213.66 SMART 1-231 (231) Show / Hide
Range on Protein: 220-472
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKMKAAHFTQYSLEMFMREITIFSKMNHPAILPFVGVTITPPFYIVTEFMEG--GCLYNRLHDNQPL-
... ..||.|||. ||  . ..    .||||.|..|         |...||| | .| .|| |  . .|  .  .|.|.|...|  | |. .......  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG

----RDPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLDANDFPKVCDFGMSRTLPENGELMSGSVGTVQWMAPEVLKSERYTE-KADVYSYGVLLW
     ..     ..  .. |..|.||.||.|||||  |.|||     |.||||..| |       .  .||  .||||||    |.  |.|..| |..|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGDSPFKKMRDVQVTIAVLSSNARPMMPPNPSRISKLIKICWDTDPDKRPDFETIAK----------I
|.|.|  ||    ..|... ..           |. .. .|. |.. ||.|||    . .          .
EMLCGYPPFP---QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 94179.m00345.AA DRK 248-475 37 8.1e-59 197.84 In-house 24-258 (258) Show / Hide
Range on Protein: 248-475
Range on HMM: 24-258/258
Sequence Identity: 37% (90 aa)

IVAVKKMKAAHFT-QYSLEMFMREITIFSKMNHPAILPFVGV-TITPPFYIVTEFMEGGCLYNRLHDNQPLRDPTKLTIIAIGVAHAMKYLHSQG--IVH
.||||....        |  | |||.. ..  || |  | |  .. |   |..|.|  | ||| |||     |   .  ... .|  | |||.    |.|
QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIH

RDLKSLNVLLDANDFPKVCDFGMSRT----LPENGELMSGSVGTVQWMAPEVLKSERYTEKADVYSYGVLLWELLTGDSPFKKMRDVQVTIAVLSSNARP
||||| | | | .   || ||| | |      . .  |   .||  | ||||| ..||||||||||... |||..|   |.  |   || ..|     ||
RDLKSHNLLVDEHWQVKVADFGLS-TRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRP

MMPPN-PSRISKLIKICWDTDPDKRPDFETIAKILES
 ||.. |    .|.. ||..||  || .. . ..||.
PMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA

Kinase 94179.m00345.AA Dicty5 264-477 37 9.6e-58 197.33 In-house 40-260 (260) Show / Hide
Range on Protein: 264-477
Range on HMM: 40-260/260
Sequence Identity: 37% (85 aa)

LEMFMREITIFSKMN--HPAILPFVGVTITPPFY--IVTEFMEGGCLYNRLHD--N---QPLRDPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLD
.. | ||.|| | .   || .  . |       |  .|||.   | | | | |  .   ||.  ...|  .||..| .|..||| .|.||||||.|.|. 
WNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLH-MAIDIAQSMRHLHSMNIIHRDLKSMNFLIT

ANDFPKVCDFGMSRTLPENGELMSGSVGTVQWMAPEVLKSERYTEKADVYSYGVLLWELLTGDSPFKKMRDVQVTIAVLSSNARPMMPPN-PSRISKLIK
 |   |. ||| ||   .|   |   |||  |||.|. ..  |..|.||||.|. |||..| ..|.. .      . | .   || .|.  |. ||.|||
ENWKIKIIDFGTSRFV-DNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIK

ICWDTDPDKRPDFETIAKILESGE
 ||   | .|| |  | |..||  
KCWQQKPHNRPSFKEICKYFESII

Kinase 94179.m00345.AA Pkinase 220-476 26 1.1e-55 196.07 Pfam 1-293 (293) Show / Hide
Range on Protein: 220-476
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

FDLKKVIGHGAFADVYWSYQVSDNMNNRIVAVKKMKAAHFTQYSLEMFMR--EITIFSKMNHPAILPFVGVTITPP-FYIVTEFMEGG----CLYNRLH-
. ....|| |.|. |   |.  .  ...|||||..|  |     ..   |  || |  ..||| |. . ..  ...  |.|.|..|||     |. ... 
YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-DNQPL-RDPTKLTIIAIGVAHAMKYLHSQGIVHRDLKSLNVLLDANDFP----KVCDFGMSRTL-PENGELMSGSVGTVQWMAPEVLK-SERYTEKADV
 .. ..  ..  .  ..  .. ...|.||.||.|||||. |.|.| |. .    |.|||| .. .   |.. |.. .||  .|||||.. .. |. |.|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSYGVLLWELLTGDSPFK------KMRDVQVTIAVLSSNARPMMPPNP---------------------SRISKLIKICWDTDPDKRPDFETIAKILES-
.|.|..|.|.|.|  ||.      . .| .. |.   .   .   |..                     .   ..|| |.. || |||    .. ||.. 
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHP

-G
  
WF