Gene 81869.m00145 (T.vaginalis)

81869.m00145

Species: T.vaginalis
Alias: 81869.m00145, TvagK0014
External Links:
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
81869.m00145.AA Protein None 271 None Fasta, JSON
81869.m00145.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 81869.m00145.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81869.m00145.AA AGC 13-262 23 2.2e-98 254.33 In-house 1-395 (395) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-395/395
Sequence Identity: 23% (93 aa)

FDVGDVIGEGRFGKVFVAREK------KSRFVCVLKIIRKKL---LTKHNLEKQLISE-------------IGLHSSFN---------HPNILR-LYGYF
|..  |||.| ||||. .|.|       .  .. .|...||    ..|.| ... ..|               |    .         ||.| . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

FDDER--IMMILEYAA----------HGTLSDLLK---KHTKFDEPTAAKYFKQ-------ILSAVEHIHS-KEVLHRD-LKPSNIMISLDNTLLLGDFG
 |...  . ...||.            . |   |.   |  .|||..|  |. .       |..|.|..|| . . ||| ||| ||..  |  . | |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAIKGNAP-----------------------------------------------------AGEIVG--TLDYISPEILNNKEYGRSADVWA--LGSILF
.. .|.                                                       .  ..|  | .|..||||    ||...| |.  || ...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGKCPFESD----------DPKETVRKIQ------NAEFSFP----------DYISPLARKLISSILQIDPTSRPT----------AKDLLNDPWI
|.|||. || .|          .|.|.  ||.      | .  ||          ...|| |. ||.  |. ||. |..          |... | || 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc 81869.m00145.AA S_TKc 13-262 33 2.5e-95 323.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-231/231
Sequence Identity: 33% (88 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLISEIGLHSSFNHPNILRLYGYFFDDERIMMILEYAAH--GTLSDLLKKHTK---
......||.| ||||. .|.||.  .. .|||.          .....|| .... .|||| .||..| | ... |..||. .  |.| |..||. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEPTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDNTLLLGDFGFAIKGNAPAGEIVGTLDYISPEILNNKEYGR-SADVWALGSILFELLT
   |.| .|..|..||..|.|..||. ..||||||.||...   .. ..|||.| .       ..||..|..||.|    ||. ..|.|..| ||.|.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GKCPFESDDPKETVRKIQNAEFSFPDYISPLARKLISSILQIDPTSRPTAKDLLN-------DPWI
|. ||.  ..... .||           || |. .|. .|| ||. |||| ..|.       .||.
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81869.m00145.AA CAMK 18-262 22 1.6e-94 305.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-262
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

VIGEGRFGKVFVAREKKSR------------FVCVLKIIRKKLLTK-------------------------HNLEKQLISEIGLHSS-------FNHPNI
..|.|.||||. ...|..               .  ||| || |..                          . .|.. .|| ....        .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLYGYFFD-------------------DERIMMIL---EYAAHG----TLSDLLKKHTK---------------FDEPTAAKYFKQILSAVEHIHSKEV
..|| .. |                   |... |..   ||.  |     | | ...|..               |.|  |..||.||.|||...||. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKPSNIMISLD-----------------NTLLLGDFGFA--IKG------------------------NAPAGEIVGTLDYIS-PEILNNKE----
 |||||| ||... .                 |.. . |||||  ...                        . .  . .||. |.. ||.|| |     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YGRSADVWALGSILFELLTGKCPFESD-------------DPKETVRKIQNAEFSFPDY------------------------ISPLARK
          ||...|.|..| ||. .|.|. ||..|             ...|. .||......||..                        .|. .. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISSILQIDPTSRPTAKDLLNDPWI
||...|| ||. |.|... ||.||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 81869.m00145.AA Pkinase 13-262 29 9.2e-93 319.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLIS--EIGLHSSFNHPNILRLYGYFFDDERIMMILEYAAHG----TLSDLLK--K
. .| .||.| ||.|. ...|... . ..|||.|.  .|.. .....   || .. ..|||||.|||..| |. .| |..||. .|     |.|...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HTKF--DEPTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDNTL----LLGDFGFA----IKGNAPAGEIVGTLDYISPEILN-NKEYGRSADVWA
|..|  .| .. .|..|||...|..||. ..||||||.||.|. ....     ..|||.|    .  |  .  ..||..|..||... ...||...|.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGSILFELLTGKCPFESD------DPKETVRKIQNAEFSFPDYIS---------------------PLARKLISSILQIDPTSRPTAKDLLNDPWI
.| ||.|.|.|. || ..      |... ...|  ....|. . .                     . ....|...|. ||..||||...|..||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81869.m00145.AA CAMKL 13-262 28 1.4e-87 279.58 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-297/297
Sequence Identity: 28% (86 aa)

FDVGDVIGEGRFGKVFVARE-KKSRFVCVLKIIRKKLLT-KHNLEKQ-----------LISEIGLHSSFN---HPNILRLYGYFFDDER------IMMIL
...|...|.| ||||  |.  .  .     ||| || .. . . .|            .  || .....|   |||| .||  . ..|       | ...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAAHGT--LSDLLKKH----TKFDEPTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDN--TLLLGDFGFAIK---G----NAPAGEIVGTLDYI
||.  |   | | ..||     ...|. | .||.||.|||...||. . |||.|| ||... ..  .. . ||||...   .    .    .  |.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEILNN--K-EYGRSADVWALGSILFELLTGKCPFESDDPK-------ETVRKIQNAEFSFP--DYISPLARKLISSILQIDPTSRPTAKDLLNDPWI
.|||..   |  .|. .|.|..| ||. ...|. ||. |. .       .  .||    . .|   ..|  .| ||...|| .|. |||.....|.|| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81869.m00145.AA PLK 13-262 31 8.8e-81 262.81 In-house 1-258 (258) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-258/258
Sequence Identity: 31% (82 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLISEIGLHSSFNHPNILRLYGYFFDDERIMMILEYAAHGTLSDLLKKH-TKFDEP
. .| ..|.| | |.. ... ... |   |.. |.|..|... . ...|| .|.. .||||.... .| |.| . . |||. ...| ...|.. ... ||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

TAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDNTLLLGDFGFAIKGNAPAGE---IVGTLDYISPEIL--NNKEYGRSADVWALGSILFELLTGKC
 .  |  || ......|.....|||||..|. .. .. . .|||| | . . .  .   . ||  ||.||.|  |.. ..  .|.|.|| |.  ||.|| 
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFESDDPKETVRKIQNAEFSFPDY--ISPLARKLISSILQIDPTSRPTAKDLLNDPWI
|||..| ||| ..|.....|||..  ||. |. || ..|. .|..|||.. .|..|. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 81869.m00145.AA Aur 13-159 45 1.3e-79 209.5 In-house 1-150 (257) Show / Hide 
Range on Protein: 13-159
Range on HMM: 1-150/257
Sequence Identity: 45% (68 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLISEIGLHSSFNHPNILRLYGYFFDDERIMMILEYAAHGTLSDLLKKH--TKFDE
|..|   |.|.||.|. ||.||. | . ||...|. . |...|.||  || ..|. ||||||..|||| ||.||  ||||| .|.|  .|.|.   .|||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

PTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMIS-LDNTLLLGDFGFAI
..||||..|| .|... ||| . |||.|| ||... ..... ..||| ..
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSV
Kinase 81869.m00145.AA MARK 13-262 32 6.6e-79 257.59 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-262/262
Sequence Identity: 32% (86 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLISEIGLHSSFNHPNILRLYGYFF--DDER-IMMILEYAAHGTLSDLLKKH--TK
. .. .||.| ..|| .|. |...    .||. |. |.. .  | . .|| .... .|||| .|. ..   . .. | .|.|||  | | | .|.|   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDEPTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDN--TLLLGDFGFAIKG--NAPAGEIVGTLDYISPEILNNKEYG-RSADVWALGSILFELL
  |. | ..|.||.|||.  ||| . |||.|| ||.|  ..     . ||||.|.   .    .  ||. | .|||.. |.|  . .|.|.|| .|. ..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGKCPFESDD--PKETVRKIQNAEFSFPDYISPLARKLISSILQIDPTSRPTAKDLLNDPWI
.|. ||. |.   ||  .||.. ....|...|. .|.||...|...|  |||.......||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81869.m00145.AA Ciliate-E2 13-262 23 1.4e-77 264.02 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

FDVGDVIGEGRFGKVFVAREKKSR-----------------------FVCVLKIIRKKLLTKHNLEKQLISEIG----------LHSSFNHPNILRLYGY
...  .||.| ||.|. .. .| .                       .   .||..|. .   . |.... ||           . .. |||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FF--DDERIMMILEYAAHGTLSDLLKKH-----------TKFDEPTAAKYFKQILS---------------AVEHIHSKE-VLHRDLKPSNIMISLDNTL
|   ||. | ...||. .|.| |..|..            .|.|  .....||||.               |.|..|||  ..|||.||.||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

LLGDFGFAIK--------------GNAPAGE---------------------IVGTLDYISPEILNNKE---------YGRSADVWALGSILFELLTGKC
 . |||.. |              .. .                        |.||. | .|||||.|.         |. ..|.|.|| ||.|.|.|| 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFESDDPKETVRKIQNAEFSFP------------------DYISPLARKLISS----ILQIDPTSRPT-AKDLLNDPWI
||         ..|.. ...||                  ...|. .  ||.     .|| ||  |.| ....|| ||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81869.m00145.AA STE 13-262 22 5.2e-72 245.54 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-359/359
Sequence Identity: 22% (81 aa)

FDVGDVIGEGRFGKVFVAREKK---------------SRFVCVLKIIRKK-------------LLTK-HNLEKQLISEIGLHSSFN--HPNILRLYGYFF
..  ..||.| ||.|. |. .|               . ...  |.....             | .| |. ..|.. || ... .|  |||| . ||..|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DD-------ERIMMILEYAAHGTLSDLLK-KH-------------TKFDEPTAAKYFKQILSA-VEHIHSKEVLHRDLKPSNIMISLDNTLLLGDFGFAI
..       . . ...|| . |.|.|..| |.             ..|.|.  |.. .||| .  ...||. . |||.||.||..       | |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KGNA-------------------PAGEIVGTLDYISPEILNN------KEYGRSADVWALGSILFELLTGKCPFESDDPK----ETVRKIQNAE------
. .                        .|||  . .||....      |.|....|.| ||  . |..||| |.    |     .. ...  ..      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---FSFPDYIS----------------------PLARKLISSILQIDPTSRPTAKDLLN--DPWI
   .  |   .                      |  .  |.  ||.||  ||||..||.   |.|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81869.m00145.AA Ciliate-E2-Unclassified 13-262 22 8.6e-72 244.82 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)

FDVGDVIGEGRFGKVFVAREKKSRFV------CVLKIIRKKLLTK---HNLEKQLISEIGLHSSFN--------------HPNILRLYGYFFDDERIMMI
. .. .||.| ||||. ...||  ..      .. .|. .|.  .   ...|.. . ..   ....              ||.|.... .| |.. | ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYAAHGTLSDLLKKHTK-----------------FDEPTAA-----KYFKQILSAVEHIHSKE-VLHRDLKPSNIMISLDN---TLLLGDFGFAIKGNA
.||. .|.|.. .||  |                 |.|  |.     .||.|||.. |..|.|  ..|||.||.||... ..    . . |||...| . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

P------------------AGEIVGTLDYI----SPEILNNKEYGRS----ADVWALGSILFELLTGKCPFESDDPKE----------------TVRKIQ
.                  .  ..||. |.    .||.| ...|. |    .|.|.|| ||.|.|.|..||.. . ..                  ..|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NAEFSFP--------DYISPLARKLIS----SILQIDPTSRPTAKDLLNDPWI
. ...||        . .|| |  .|.    ..|. .| .|.|....|| ||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81869.m00145.AA ULK 13-262 27 7.8e-70 238.31 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-262
Range on HMM: 1-329/329
Sequence Identity: 27% (92 aa)

FDVGDVIGEGRFGKVFVAREKKSR----FVCVLKIIRKKLLTKHNLE-------KQLISEIGLHSSFN--------HPNILRLYGYFFDDER--IMMILE
. . ...|.| ||||. .| ||.      ... |.| |. . . | |       ..|..|| .    .        |||| .|| .| ..    | .|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAAHGTLSDLLKKHTKFDEPT----------AAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDN------------TLLLGDFGFAIKGNAP-----
|  .|.|....||. |. |.|          | ..|||||..  ..|.. . |||.||.||.|. ..            .| ..||||| . . .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-AGEIV------GTLDYISPEILN----NKEYGRS-ADVWALGSILFELLTGKCPFESDDPKETV-----RK----------IQNAEFSFPDY-----IS
 .   |      ||  | .|.||.    .|.|. . .|.| || |..|.|.||.||..  . ...     .           |..  . ||..     ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PLARKLISSILQIDPTSRPTAKDLLNDPWI
|  . ||.  ||.|.. | .  .|.| ||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81869.m00145.AA Aur 170-262 42 9.2e-52 134.52 In-house 163-257 (257) Show / Hide 
Range on Protein: 170-262
Range on HMM: 163-257/257
Sequence Identity: 42% (40 aa)

GTLDYISPEILNNKEYGRSADVWALGSILFELLTGKCPFES-DDPKETVRKIQ-NAEFSFPDYISPLARKLISSILQIDPTSRPTAKDLLNDPWI
|||||..||. ...... . |.|.|| ...||..|. |||| .. .|| ..|. . ...||..||. |. ||| ||| || .| | .. .| |||
GTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 81869.m00145.AA TyrKc 13-260 21 5.9e-23 83.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-260
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FDVGDVIGEGRFGKVFVAREKKSRFVCVLKIIRKKLLTKHNLEKQLISEIGLHSSF--NHPNILRLYGYFFDD-------ERIMMILEYAAHGTLSDLLK
   |...||| ||.|. .. |     .  | ...        .. ...|. . ...  .||||.||||.  ..       | .|...||..|| | | |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KHTK-FDEPTAAKYFKQILSAVEHIHSKEVLHRDLKPSNIMISLDNTLLLGDFGFAIKGNAP-----AGEIVGT-----LD------YISPEILNNKEYG
|| . .  ..  ..  || .  |..||| . ||||   |.... ..|   .||| . ..        ...   .      .        .|| .| ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RSADVWALGSILFELLT-GKCPFES-----DDPKETVRKIQNAEF-SFPDY--------ISPLARKLISSILQIDPTSRPTAKDLLNDP
   |||. |  ..|..| |. | .       ...| ...... .    |..         ..   .....  . || .||| ...  . 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81869.m00145.AA Pkinase_Tyr 13-137 28 5.1e-21 71.8 Pfam 1-137 (270) Show / Hide 
Range on Protein: 13-137
Range on HMM: 1-137/270
Sequence Identity: 28% (39 aa)

FDVGDVIGEGRFGKVFVAREK----KSRFVCVLKIIRKKLLTKHN-LEKQLISEIGLHSSF-NHPNILRLYGYFF-DDER--IMMILEYAAHGTLSDLLK
   | ..||| ||.|. .. |    . .  .  |.. |   .... . . ...|. . ... .||||.||||    ..|   |....||..|| | | |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KH----TKFDEPTAAKYFKQILSAVEHIHSKEVLHRDL
||     ... ..  ..  || .. |. .||   ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 81869.m00145.AA Pkinase_Tyr 176-222 26 0.392334 4.46 Pfam 182-231 (270) Show / Hide 
Range on Protein: 176-222
Range on HMM: 182-231/270
Sequence Identity: 26% (13 aa)

SPEILNNKEYGRSADVWALGSILFELLT-GKCP-FESDDPKETVRKI-QN
.|| .|....    |||. |  ..|..| |. | ..  .. | ...| ..
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